Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintracellularly calcium-gated channel activity

BEST1 TTYH3

5.56e-0420352GO:0141147
GeneOntologyMolecularFunctionintracellularly calcium-gated chloride channel activity

BEST1 TTYH3

5.56e-0420352GO:0005229
GeneOntologyMolecularFunctioncysteine-type endopeptidase inhibitor activity involved in apoptotic process

VIL1 RPS6KA1

8.04e-0424352GO:0043027
GeneOntologyMolecularFunctiontransforming growth factor beta receptor binding

SMURF1 SMURF2

1.34e-0331352GO:0005160
GeneOntologyBiologicalProcessregulation of G protein-coupled receptor signaling pathway

GIPR PDE3A PLD2 RGS3 CNTN2

1.11e-05181345GO:0008277
DomainHECT

SMURF1 ITCH SMURF2

1.71e-0527353PF00632
DomainHECTc

SMURF1 ITCH SMURF2

1.71e-0527353SM00119
DomainHECT_dom

SMURF1 ITCH SMURF2

1.71e-0527353IPR000569
DomainHECT

SMURF1 ITCH SMURF2

1.71e-0527353PS50237
DomainWW

SMURF1 ITCH SMURF2

9.24e-0547353PF00397
DomainWW

SMURF1 ITCH SMURF2

9.84e-0548353SM00456
DomainC2

SMURF1 ITCH SMURF2 RGS3

1.02e-04131354PF00168
DomainWW_DOMAIN_2

SMURF1 ITCH SMURF2

1.18e-0451353PS50020
DomainWW_DOMAIN_1

SMURF1 ITCH SMURF2

1.18e-0451353PS01159
DomainC2

SMURF1 ITCH SMURF2 RGS3

1.22e-04137354SM00239
DomainWW_dom

SMURF1 ITCH SMURF2

1.25e-0452353IPR001202
DomainC2

SMURF1 ITCH SMURF2 RGS3

1.40e-04142354PS50004
Domain-

SMURF1 ITCH SMURF2 RGS3

1.64e-041483542.60.40.150
DomainC2_dom

SMURF1 ITCH SMURF2 RGS3

2.43e-04164354IPR000008
DomainKringle

HGF HGFAC

4.56e-0417352IPR000001
DomainKringle

HGF HGFAC

4.56e-0417352PF00051
DomainKRINGLE_1

HGF HGFAC

4.56e-0417352PS00021
DomainKringle_CS

HGF HGFAC

4.56e-0417352IPR018056
DomainKR

HGF HGFAC

4.56e-0417352SM00130
DomainKRINGLE_2

HGF HGFAC

4.56e-0417352PS50070
DomainKringle-like

HGF HGFAC

1.63e-0332352IPR013806
PathwayREACTOME_MET_RECEPTOR_ACTIVATION

HGF HGFAC

6.10e-056292M27644
PathwayREACTOME_MET_RECEPTOR_ACTIVATION

HGF HGFAC

6.10e-056292MM15346
PathwayPID_TGFBR_PATHWAY

SMURF1 ITCH SMURF2

1.81e-0454293M286
PathwayBIOCARTA_EFP_PATHWAY

SMURF1 SMURF2

4.82e-0416292M22011
PathwayKEGG_ENDOCYTOSIS

SMURF1 ITCH PLD2 SMURF2

4.86e-04181294M1519
Pubmed

A role for ubiquitin ligases and Spartin/SPG20 in lipid droplet turnover.

SMURF1 ITCH SMURF2

5.21e-08835319307600
Pubmed

Patched-1 proapoptotic activity is downregulated by modification of K1413 by the E3 ubiquitin-protein ligase Itchy homolog.

SMURF1 ITCH SMURF2

1.11e-071035325092867
Pubmed

Damage-induced ubiquitylation of human RNA polymerase II by the ubiquitin ligase Nedd4, but not Cockayne syndrome proteins or BRCA1.

SMURF1 ITCH SMURF2

1.53e-071135317996703
Pubmed

USP11 augments TGFβ signalling by deubiquitylating ALK5.

SMURF1 ITCH SMURF2

1.53e-071135322773947
Pubmed

NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.

SMURF1 ITCH SMURF2

2.04e-071235324107629
Pubmed

HECT E3 Ubiquitin Ligase Itch Functions as a Novel Negative Regulator of Gli-Similar 3 (Glis3) Transcriptional Activity.

SMURF1 ITCH SMURF2

3.37e-071435326147758
Pubmed

Assembly and structure of Lys33-linked polyubiquitin reveals distinct conformations.

SMURF1 ITCH SMURF2

5.18e-071635325723849
Pubmed

RNF11 sequestration of the E3 ligase SMURF2 on membranes antagonizes SMAD7 down-regulation of transforming growth factor β signaling.

SMURF1 ITCH SMURF2

6.29e-071735328292929
Pubmed

SCFFBXL¹⁵ regulates BMP signalling by directing the degradation of HECT-type ubiquitin ligase Smurf1.

SMURF1 ITCH SMURF2

8.95e-071935321572392
Pubmed

Activation of hepatocyte growth factor in the injured tissues is mediated by hepatocyte growth factor activator.

HGF HGFAC

9.84e-0723528631970
Pubmed

The functions and regulation of Smurfs in cancers.

SMURF1 SMURF2

9.84e-07235231899247
Pubmed

Smurf2 induces ubiquitin-dependent degradation of Smurf1 to prevent migration of breast cancer cells.

SMURF1 SMURF2

9.84e-07235218927080
Pubmed

Structure and function of hepatocyte growth factor.

HGF HGFAC

9.84e-0723521838014
Pubmed

Multiple myeloma cells catalyze hepatocyte growth factor (HGF) activation by secreting the serine protease HGF-activator.

HGF HGFAC

9.84e-07235215172968
Pubmed

SMURF1 and SMURF2 in Progenitor Cells from Articular Cartilage and Meniscus during Late-Stage Osteoarthritis.

SMURF1 SMURF2

9.84e-07235233090007
Pubmed

Trans-ethnic meta-analysis identifies common and rare variants associated with hepatocyte growth factor levels in the Multi-Ethnic Study of Atherosclerosis (MESA).

HGF HGFAC

9.84e-07235225998175
Pubmed

Elevated serum concentrations of activated hepatocyte growth factor activator in patients with multiple myeloma.

HGF HGFAC

9.84e-07235218691255
Pubmed

Cytoplasmic YAP1-mediated ESCRT-III assembly promotes autophagic cell death and is ubiquitinated by NEDD4L in breast cancer.

SMURF1 ITCH SMURF2

1.23e-062135337005481
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

SMURF1 ITCH SMURF2

2.39e-062635326949039
Pubmed

Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer.

HGF HGFAC

2.95e-06335218422749
Pubmed

Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma.

SMURF1 SMURF2

2.95e-06335237537194
Pubmed

GPR119 regulates murine glucose homeostasis through incretin receptor-dependent and independent mechanisms.

GIPR GPR119

2.95e-06335221068156
Pubmed

The Smurf ubiquitin ligases regulate tissue separation via antagonistic interactions with ephrinB1.

SMURF1 SMURF2

2.95e-06335223475958
Pubmed

Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2.

SMURF1 SMURF2

2.95e-06335225051198
Pubmed

Activation of hepatocyte growth factor (HGF) by endogenous HGF activator is required for metanephric kidney morphogenesis in vitro.

HGF HGFAC

2.95e-06335211032833
Pubmed

USF2 inhibits the transcriptional activity of Smurf1 and Smurf2 to promote breast cancer tumorigenesis.

SMURF1 SMURF2

2.95e-06335230244169
Pubmed

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice.

SMURF1 SMURF2

2.95e-06335215173588
Pubmed

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception.

SMURF1 SMURF2

2.95e-06335224925320
Pubmed

GIPR Is Predominantly Localized to Nonadipocyte Cell Types Within White Adipose Tissue.

GIPR NDOR1

5.90e-06435235192688
Pubmed

Non-proteolytic ubiquitin modification of PPARγ by Smurf1 protects the liver from steatosis.

SMURF1 SMURF2

5.90e-06435230566427
Pubmed

Long non-coding RNA ARHGAP5-AS1 inhibits migration of breast cancer cell via stabilizing SMAD7 protein.

SMURF1 SMURF2

5.90e-06435234370213
Pubmed

Tumor necrosis factor promotes Runx2 degradation through up-regulation of Smurf1 and Smurf2 in osteoblasts.

SMURF1 SMURF2

5.90e-06435216373342
Pubmed

Nedd8 targets ubiquitin ligase Smurf2 for neddylation and promote its degradation.

SMURF1 SMURF2

5.90e-06435227086113
Pubmed

Role of hypoxia on microRNA-dependant regulation of HGFA - HGF - c-Met signalling pathway in human progenitor and mature endothelial cells.

HGF HGFAC

5.90e-06435236182093
Pubmed

The WW1 Domain Enhances Autoinhibition in Smurf Ubiquitin Ligases.

SMURF1 SMURF2

5.90e-06435231628949
Pubmed

An integrated bioinformatics platform for investigating the human E3 ubiquitin ligase-substrate interaction network.

SMURF1 SMURF2

9.82e-06535228839186
Pubmed

Impaired Smad7-Smurf-mediated negative regulation of TGF-beta signaling in scleroderma fibroblasts.

SMURF1 SMURF2

9.82e-06535214722617
Pubmed

Pivotal role of the C2 domain of the Smurf1 ubiquitin ligase in substrate selection.

SMURF1 SMURF2

9.82e-06535221402695
Pubmed

NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.

SMURF1 SMURF2

9.82e-06535228798345
Pubmed

Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity.

SMURF1 SMURF2

9.82e-06535220937913
Pubmed

Inhibition of HECT E3 ligases as potential therapy for COVID-19.

SMURF1 SMURF2

9.82e-06535233762578
Pubmed

N4WBP5A (Ndfip2), a Nedd4-interacting protein, localizes to multivesicular bodies and the Golgi, and has a potential role in protein trafficking.

SMURF1 ITCH

1.47e-05635215252135
Pubmed

Smad6-specific recruitment of Smurf E3 ligases mediates TGF-β1-induced degradation of MyD88 in TLR4 signalling.

SMURF1 SMURF2

1.47e-05635221897371
Pubmed

ICAP-1 monoubiquitylation coordinates matrix density and rigidity sensing for cell migration through ROCK2-MRCKα balance.

SMURF1 SMURF2

1.47e-05635228049720
Pubmed

Cerebral cavernous malformation 2 protein promotes smad ubiquitin regulatory factor 1-mediated RhoA degradation in endothelial cells.

SMURF1 SMURF2

1.47e-05635219318350
Pubmed

Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways.

SMURF1 SMURF2

1.47e-05635222921829
Pubmed

Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment.

ITCH SMURF2

1.47e-05635220676133
Pubmed

Ubiquitination-mediated degradation of SIRT1 by SMURF2 suppresses CRC cell proliferation and tumorigenesis.

SMURF1 SMURF2

1.47e-05635232361710
Pubmed

MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway.

SMURF1 ITCH

1.47e-05635235820905
Pubmed

Hepatitis C virus/human interactome identifies SMURF2 and the viral protease as critical elements for the control of TGF-β signaling.

SMURF1 SMURF2

1.47e-05635223781096
Pubmed

CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription.

SMURF1 SMURF2

2.06e-05735214701756
Pubmed

A cell-based high-throughput screening method based on a ubiquitin-reference technique for identifying modulators of E3 ligases.

SMURF1 SMURF2

2.06e-05735230587574
Pubmed

SET9-Mediated Regulation of TGF-β Signaling Links Protein Methylation to Pulmonary Fibrosis.

SMURF1 SMURF2

2.06e-05735227292644
Pubmed

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.

ITCH SMURF2

2.06e-05735223644597
Pubmed

The Nedd8 Non-covalent Binding Region in the Smurf HECT Domain is Critical to its Ubiquitn Ligase Function.

SMURF1 SMURF2

2.06e-05735228169289
Pubmed

Selective compounds enhance osteoblastic activity by targeting HECT domain of ubiquitin ligase Smurf1.

SMURF1 SMURF2

2.74e-05835228881580
Pubmed

Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.

HGF DDR1

2.74e-05835233930309
Pubmed

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain.

ITCH SMURF2

2.74e-05835217719543
Pubmed

Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.

SMURF1 SMURF2

2.74e-05835220484049
Pubmed

Formin 2 Regulates Lysosomal Degradation of Wnt-Associated β-Catenin in Neural Progenitors.

SMURF1 SMURF2

3.53e-05935229659741
Pubmed

Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1).

SMURF1 SMURF2

4.40e-051035215221015
Pubmed

Transforming growth factor-beta stimulates p300-dependent RUNX3 acetylation, which inhibits ubiquitination-mediated degradation.

SMURF1 SMURF2

4.40e-051035215138260
Pubmed

Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis.

HGF DDR1

7.62e-051335236198802
Pubmed

K27-linked ubiquitination of BRAF by ITCH engages cytokine response to maintain MEK-ERK signaling.

ITCH SMURF2

8.89e-051435231015455
Pubmed

TSC-22 promotes transforming growth factor β-mediated cardiac myofibroblast differentiation by antagonizing Smad7 activity.

SMURF1 SMURF2

8.89e-051435221791611
Pubmed

Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer.

SMURF1 SMURF2

8.89e-051435229263404
Pubmed

A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.

SMURF1 ITCH

1.17e-041635222496338
Pubmed

A strategy for modulation of enzymes in the ubiquitin system.

USP14 ITCH

1.33e-041735223287719
Pubmed

PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.

PDE3A CNTN2

2.04e-042135239304345
Pubmed

Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung.

MFAP4 ZDHHC6

2.04e-042135215328023
Pubmed

Neuronal basic helix-loop-helix proteins Neurod2/6 regulate cortical commissure formation before midline interactions.

NDOR1 CNTN2

2.04e-042135223303943
Pubmed

USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling.

ITCH SMURF2

2.24e-042235224850914
Pubmed

Bone morphogenetic proteins.

SMURF1 SMURF2

2.46e-042335215621726
Pubmed

Regulation of planar cell polarity by Smurf ubiquitin ligases.

SMURF1 SMURF2

2.91e-042535219379695
Pubmed

Bmp2 and Notch cooperate to pattern the embryonic endocardium.

SMURF1 SMURF2

3.15e-042635229853617
Pubmed

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

HGF DDR1

3.66e-042835218593464
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

GIPR HGF HGFAC

4.05e-0414335320424473
Pubmed

TRAF4 promotes TGF-β receptor signaling and drives breast cancer metastasis.

SMURF1 SMURF2

4.20e-043035223973329
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SMURF1 USP14 DDR1 BEST1 TTYH3 ITCH SMURF2

6.09e-04148935728611215
Pubmed

14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation.

SMURF1 PDE3A

8.26e-044235223444366
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

SMURF1 ITCH SMURF2

9.38e-0419135333762435
InteractionRNF11 interactions

SMURF1 USP14 DDR1 ITCH SMURF2

1.03e-05169355int:RNF11
InteractionTIGIT interactions

DDR1 ITCH ZDHHC6

1.21e-0526353int:TIGIT
InteractionFBXL15 interactions

SMURF1 ITCH SMURF2

1.70e-0529353int:FBXL15
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ITCH SMURF2 RGS3

1.83e-0536263823
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FANCC MFAP4 TTYH3 XKR6

8.76e-061673546c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCellControl-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

HGF TTYH3 TRIM47 CARNS1

1.10e-05177354470f54fe2b21c7350ea471e02039461a3808f700
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|368C / Donor, Lineage, Cell class and subclass (all cells)

TTYH3 ITCH PLD2 RPS6KA1

1.13e-05178354536a601abcc60867949ea06e9aafb6c7b799b56b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.46e-05190354841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.49e-05191354b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.52e-051923546f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.52e-051923543d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.52e-05192354deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.55e-05193354fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4 PDE3A

1.58e-0519435460622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial|6m / Sample Type, Dataset, Time_group, and Cell type.

HGF BNC2 MFAP4 ACBD3

1.78e-052003542cc98abf11f5b58707de45a2282f03d47f00f035
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

HGF BNC2 MFAP4 ACBD3

1.78e-052003540f7431f670f3a175377cefae3479403a881bb8fb
ToppCellcontrol-Myeloid-Monocyte-derived_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FANCC GIPR CARNS1

2.03e-0414635369e9c1ec6eec1151290227902e75e77a4aecc8db
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l14|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HGF HGFAC CARNS1

2.29e-041523530fda8980b10ce16179dea92301db74d728f41794
ToppCellmetastatic_Brain-Fibroblasts-Smooth_muscle_cells|metastatic_Brain / Location, Cell class and cell subclass

MFAP4 PDE3A CNTN2

2.96e-041663530da2c6ea1e62f1aafabafbbfbbcc6f7011739346
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST1 TTYH3 SLC15A3

3.01e-041673532dc3de562a26077cb76855b725cf278a272d3276
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BEST1 ACBD3 ACOX2

3.01e-041673538fede587572d465cb63f7828141a574185bbb819
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MFAP4 XKR6 TRIM47

3.07e-04168353d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZDHHC6 RGS3 RPS6KA1

3.12e-0416935396aafb687b34d4b59f75c24e176b0b442e864245
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

VIL1 BEST1 TTYH3

3.17e-041703533a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCellControl-Myeloid-MoAM2,_CCL18|Control / Condition, Lineage and Cell class

HGF TTYH3 TRIM47

3.40e-041743534c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

3.75e-0418035308ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

APOO SLC15A3 ACBD3

3.75e-04180353310a311c3ed924c912a800cf287a825de44b8775
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

3.75e-041803539b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

3.81e-041813539e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellfacs-Marrow-T-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGF DDR1 RPS6KA1

3.81e-041813537286700396676fdc41d9723979b8b408177aceb9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VIL1 GIPR USP14

3.81e-04181353c35ca98c474e31917e0a53c092397e0d8d18b37c
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SMURF1 HGF TTYH3

3.81e-041813532b9b460239d67fd480cee60820cdb306109d3567
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

3.81e-04181353a8e9ea73c24109a5d4d28bc0577cc869ad932a4d
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SMURF1 HGF TTYH3

3.81e-041813532a1aa4a0ec7bc367857beaff543135e4345c835b
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 PLD2 RGS3

3.81e-04181353709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MFAP4 PDE3A

3.87e-04182353af65f0fc3f9e5d9ce69ee5faaf5b6cb7f8412e0c
ToppCellNS-moderate-d_16-33-Lymphoid-NK|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BNC2 MFAP4 PDE3A

3.87e-04182353fb503f8ecd013f1f2161a5841572b57cfcddb6fa
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MFAP4 PDE3A

3.87e-04182353b7d532feb73167e05475855061b35a209583f44c
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MFAP4 PLD2 RGS3

3.94e-04183353ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

3.94e-041833537eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

3.94e-0418335393213124e55d1b673dd345188caf8b5bd31d99fe
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MFAP4 WDR5B CARNS1

3.94e-04183353dc9602bed3136db91faeffef177006246dc92743
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.06e-041853539f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HGFAC DDR1 PDE3A

4.06e-04185353487fa382232564f075960899d50afa0edae5d258
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

HGF BNC2 PDE3A

4.06e-04185353fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HGF BNC2 PDE3A

4.13e-041863538915436d09775f2828a7678af203b1082b36e21c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

4.13e-0418635390eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

4.13e-04186353bd8a9753df219084e19e7f94447856e86608325c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.19e-0418735313731298bc562ec29582f5da1b4c97261284f6f1
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMURF1 ITCH RGS3

4.19e-041873533699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMURF1 ITCH RGS3

4.19e-04187353033ba52c0c2f9978784947098fa697368ae44834
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A TRIM47 RGS3

4.19e-0418735366ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A TRIM47 RGS3

4.26e-0418835350b27fc12347ca16bd62333baf345c83cb422a8f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

4.26e-04188353d9692b6048d9b85524a07a1807bdd4757731c151
ToppCellP07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A TRIM47 RGS3

4.26e-041883535bc1537e079c7435196c163bff5f639ea392a33a
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A TRIM47 RGS3

4.33e-041893538e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.33e-04189353a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4

4.33e-041893532a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A TRIM47 RGS3

4.33e-04189353fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.33e-0418935345e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.39e-041903537986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_MOBP_COL18A1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

4.39e-04190353396b7225c2430db3dc55a3d0db70239b71987229
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HGF BNC2 MFAP4

4.39e-04190353d60395739458d7f47a3350ade751fe3819500320
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BEST1 CARNS1 CNTN2

4.46e-041913532110a1dd10730ad7ee7a265fb1716ab3ddafcf4a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.46e-04191353fa380a8752de158974b2ae5e741573439719cc0d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.46e-04191353156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.46e-0419135314057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.53e-04192353dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.53e-04192353162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MFAP4 PDE3A

4.53e-04192353bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.53e-041923534e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HGF MFAP4 PDE3A

4.53e-041923530ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

HGF BNC2 MFAP4

4.60e-04193353ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.67e-041943538c37bedb23285735ff3828db3889897fada8c95d
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BNC2 MFAP4 PDE3A

4.67e-041943536e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.67e-041943535f5f0cdeacd5e1b28717d78dabdb9eb95f661e36
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.67e-0419435385e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCell18-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

BNC2 MFAP4 RGS3

4.74e-04195353f86737bff21d81673238813df61a15cfe88d0b15
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HGF BNC2 MFAP4

4.74e-04195353f54bc4454270ff06e85596f98199372b50d0179f
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 MFAP4 PDE3A

4.81e-04196353dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDR1 TTYH3 CNTN2

4.81e-04196353256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MIIP BNC2 PDE3A

4.88e-04197353bed8a9b73af5caee51b1232b31c24a59353658df
ToppCellBronchial-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MIIP BNC2 PDE3A

4.88e-04197353b7d5073d44aa1e2cb83ea8d8104c5ed662665755
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BEST1 TTYH3 PLD2

4.88e-04197353e2983ae16c72371fbf0e5c123de9f4d900724e5e
ToppCell10x5'v1-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TTYH3 SLC15A3 TRIM47

4.88e-04197353075044c17f1c52008cd3c292c15cbf485b50411e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TTYH3 SLC15A3 ACOX2

4.88e-04197353989eaf7ecef8683e3ec6ec024fd193a2f5861b26
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 MFAP4 TRIM47

4.95e-04198353c66097ae9ba0b50561083c423565665958ef0bb8
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

HGF BNC2 MFAP4

4.95e-041983533ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Proliferative_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MFAP4 TRIM47 RGS3

4.95e-0419835377c81ec602ab553a544c3d9b1e66181b6f000d12
ToppCellMonocytes-Phagocytic_CD16+_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

BEST1 TTYH3 SLC15A3

4.95e-0419835309009cc966bf1503c3b15dfa079a6c5f6ad1f507
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BNC2 PDE3A RGS3

4.95e-0419835322e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellbackground-Hepatic_Stellate_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

HGF MFAP4 PDE3A

4.95e-04198353bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell10x3'2.3-week_12-13-Myeloid_macrophage-stroma-stromal_macrophage|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

BEST1 TTYH3 SLC15A3

4.95e-041983539a89083280d4253f282300cdf1e61746d1f32407
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BNC2 MFAP4 PDE3A

4.95e-0419835321cf4d81386761d09d0f6829c01c198e5524176d
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

BNC2 MFAP4 PDE3A

5.03e-041993534bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HGF BNC2 MFAP4

5.03e-04199353a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellTransverse-Macrophage-LYVE1_Macrophage|Transverse / Region, Cell class and subclass

HGF TTYH3 SLC15A3

5.03e-04199353facf79c256db5ae57bdb613e86ec90616a6f67ca
ToppCellTransverse-(6)_Macrophage-(61)_LYVE1_Macrophage|Transverse / shred on region, Cell_type, and subtype

HGF TTYH3 SLC15A3

5.03e-04199353dcc2a7f4d1fa30aaaad655dd59c5a2b039d264bf
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF BNC2 PDE3A

5.10e-04200353cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF BNC2 MFAP4

5.10e-042003533dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCell15-Airway|15 / Age, Tissue, Lineage and Cell class

BNC2 MFAP4 RGS3

5.10e-04200353ba4b8d5becf81351901c2ecac74ffa28e29586f3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HGF BNC2 PDE3A

5.10e-04200353311fab076f2ceb258e3970eb21e39344b894042a
ToppCellBiopsy_Other_PF-Mesenchymal|Biopsy_Other_PF / Sample group, Lineage and Cell type

HGF MFAP4 PDE3A

5.10e-04200353d6fcdd48858b53b5a8d18ae14b2dc4d9af41b070
ToppCellNeuronal-Inhibitory-iA|Neuronal / cells hierarchy compared to all cells using T-Statistic

HGFAC DDR1 PDE3A

5.10e-042003535ef4a3dc18a44292184a59ced916183c0699b01e
Diseasehigh grade glioma (is_marker_for)

HGF DDR1 CNTN2

1.42e-0542333DOID:3070 (is_marker_for)
Diseasevital capacity

USP14 BNC2 BEST1 PDE3A TCF20 CARNS1 SMURF2 RPS6KA1

5.04e-051236338EFO_0004312
DiseaseLiver Cirrhosis, Experimental

HGF MFAP4 TCF20 SLC15A3 RGS3 ACOX2

1.93e-04774336C0023893
Diseasejoint hypermobility measurement

XKR6 SMURF2

6.27e-0433332EFO_0007905
Diseasetongue squamous cell carcinoma (is_marker_for)

FANCC HGF

7.88e-0437332DOID:0050865 (is_marker_for)
Diseasediet measurement

GIPR BNC2 ITCH XKR6 TCF20 RGS3

9.68e-041049336EFO_0008111
Diseasehepatocyte growth factor measurement

HGF HGFAC

1.11e-0344332EFO_0006903
DiseaseThrombus

HGF PDE3A

1.22e-0346332C0087086
DiseaseThrombosis

HGF PDE3A

1.38e-0349332C0040053
Diseaselow density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio

GIPR HGFAC XKR6

1.44e-03200333EFO_0004611, EFO_0020945
Diseaserisk-taking behaviour

BNC2 XKR6 TCF20 RGS3 CNTN2

1.49e-03764335EFO_0008579
Diseasecorpus callosum posterior volume measurement

HGF XKR6

1.55e-0352332EFO_0010298
Diseasefactor XI measurement, fibrinogen measurement, tissue plasminogen activator measurement, factor VII measurement

HGFAC ITCH

1.80e-0356332EFO_0004619, EFO_0004623, EFO_0004694, EFO_0004791
Diseasepyroglutamine measurement

BNC2 CARNS1

1.93e-0358332EFO_0005408
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

GIPR HGFAC PDE3A

1.94e-03222333EFO_0008317, EFO_0020943
DiseaseC-reactive protein measurement

GIPR HGFAC BNC2 XKR6 PLD2 RPS6KA1

1.98e-031206336EFO_0004458
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

GIPR HGFAC PDE3A

2.02e-03225333EFO_0008317, EFO_0020947
DiseaseFEV/FEC ratio

BNC2 PDE3A SYS1 ITCH SMURF2 CNTN2

2.16e-031228336EFO_0004713
Diseasearterial stiffness measurement

BNC2 TCF20

2.34e-0364332EFO_0004517
Diseaseaspartate aminotransferase measurement

HGFAC PDE3A XKR6 CNTN2 ACOX2

3.11e-03904335EFO_0004736
Diseasemonounsaturated fatty acids; 16:1, 18:1 measurement

HGFAC BEST1

3.45e-0378332EFO_0022187

Protein segments in the cluster

PeptideGeneStartEntry
WLEDGRELGYAYRAL

ACOX2

96

Q99424
LHGLGWTLRDYVRGY

BNC2

206

Q6ZN30
ELYGCLWRDGLLSYT

DDR1

181

Q08345
GFYLRDWILELYGVD

CARNS1

696

A5YM72
SEEGHFRYYLLLGWG

GIPR

251

P48546
LLCWRGSIYKLLYGE

BEST1

21

O76090
EISGWYYLLGEHLGR

RGS3

251

P49796
VSGERLYDWGLRGYI

APOO

161

Q9BUR5
WRPYLAYLAGVLGIL

PDE3A

236

Q14432
LYLVLERYLWLLGVG

GPR119

256

Q8TDV5
EQRWGFGLEELYGLA

ACBD3

76

Q9H3P7
GWGYTGLINYDGLLR

HGF

616

P14210
YLYGIISWGDGCGRL

HGFAC

611

Q04756
WELLDRQGAYFYLAG

NDOR1

536

Q9UHB4
GLDYGGVAREWFFLL

ITCH

586

Q96J02
LDRVGIHGWSYGGYL

DPP8

746

Q6V1X1
ALLWLLAFYYGPRDG

FANCC

421

Q00597
NGILLGYEIRYWKAG

CNTN2

841

Q02246
GWLADVYLGRYRAVA

SLC15A3

91

Q8IY34
YYGSLGLWLALVDGL

SYS1

26

Q8N2H4
VLGEGALDRGTYYWE

TRIM47

471

Q96LD4
GAGALYDYGRWLVVV

MT-ND6

141

P03923
LGFGRADGEYWLGLQ

MFAP4

101

P55083
RLRPYLGYDWIAGSL

MIIP

171

Q5JXC2
EGLDYGGVAREWLYL

SMURF1

436

Q9HCE7
GLDYGGVAREWLYLL

SMURF2

431

Q9HAU4
FILATRGLRYWLYGD

ZDHHC6

356

Q9H6R6
RGLRYWLYGDKILDD

ZDHHC6

361

Q9H6R6
KWLGHFYGGDCYLLL

VIL1

416

P09327
GDVGTDLWLALDYYR

XKR6

141

Q5GH73
ADRLIIIWGAYDGKY

WDR5B

61

Q86VZ2
WANGIYLVCGRLYGL

TCF20

1861

Q9UGU0
LYGAVAERLWEYGFL

ZSCAN29

441

Q8IWY8
LSGGGDWHIAYVLLY

USP14

466

P54578
DWYRWLGYLGLLLLD

TTYH3

206

Q9C0H2
VVAFLGGLDLAYGRW

PLD2

451

O14939
GGLDLAYGRWDDLHY

PLD2

456

O14939
YDEGCDIWSLGILLY

RPS6KA1

591

Q15418