Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction[heparan sulfate]-glucosamine N-sulfotransferase activity

NDST2 NDST4

4.96e-054582GO:0015016
GeneOntologyMolecularFunctionN-acetylglucosamine deacetylase activity

NDST2 NDST4

4.96e-054582GO:0050119
DomainHSNSD

NDST2 NDST4

5.86e-054592PF12062
DomainHeparan_SO4_deacetylase

NDST2 NDST4

5.86e-054592IPR021930
DomainPTPc_motif

PTPRC PTPRO DUSP4

8.58e-0459593SM00404
DomainTyr_Pase_cat

PTPRC PTPRO DUSP4

8.58e-0459593IPR003595
DomainTyr_Pase_AS

PTPRC PTPRO DUSP4

1.59e-0373593IPR016130
DomainTYR_PHOSPHATASE_1

PTPRC PTPRO DUSP4

2.54e-0386593PS00383
DomainTYR_PHOSPHATASE_2

PTPRC PTPRO DUSP4

2.63e-0387593PS50056
DomainTYR_PHOSPHATASE_dom

PTPRC PTPRO DUSP4

2.63e-0387593IPR000387
Domain-

PTPRC PTPRO DUSP4

3.08e-03925933.90.190.10
DomainPID

TBC1D4 NUMB

3.52e-0328592PF00640
DomainProt-tyrosine_phosphatase-like

PTPRC PTPRO DUSP4

3.79e-0399593IPR029021
DomainPID

TBC1D4 NUMB

4.58e-0332592PS01179
Domain-

RIPOR2 NF1 ZER1 ARMC2

5.31e-032225941.25.10.10
DomainSulfotransferase_dom

NDST2 NDST4

5.77e-0336592IPR000863
DomainSulfotransfer_1

NDST2 NDST4

5.77e-0336592PF00685
DomainPTPc

PTPRC PTPRO

5.77e-0336592SM00194
DomainANF_lig-bd_rcpt

TAS1R1 GRIA3

6.09e-0337592IPR001828
DomainANF_receptor

TAS1R1 GRIA3

6.09e-0337592PF01094
DomainEGF

FRAS1 FAT1 TENM4 VWA2

6.47e-03235594SM00181
DomainPeripla_BP_I

TAS1R1 GRIA3

6.74e-0339592IPR028082
DomainTYR_PHOSPHATASE_PTP

PTPRC PTPRO

6.74e-0339592PS50055
DomainPTB

TBC1D4 NUMB

7.08e-0340592SM00462
DomainARM_REPEAT

ZER1 ARMC2

7.08e-0340592PS50176
DomainARM

ZER1 ARMC2

7.08e-0340592SM00185
DomainPTPase_domain

PTPRC PTPRO

7.43e-0341592IPR000242
DomainY_phosphatase

PTPRC PTPRO

7.43e-0341592PF00102
DomainPTB/PI_dom

TBC1D4 NUMB

7.43e-0341592IPR006020
DomainEGF-like_dom

FRAS1 FAT1 TENM4 VWA2

7.91e-03249594IPR000742
Pubmed

Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development.

NDST2 NDST4 PROX1

5.45e-062060317107998
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TBC1D4 WDR11 RPS6KA2 FBRSL1 ADGRG1 NUMB SCAF11 H6PD SHROOM2 ARMC2 TET3 DNAH1

7.54e-061489601228611215
Pubmed

AMACO is a component of the basement membrane-associated Fraser complex.

FRAS1 VWA2

8.77e-06360224232570
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

FRAS1 TENM4 ERAP2 NDST2 H6PD

9.71e-0616460532409323
Pubmed

Alternatively spliced isoforms of WT1 control podocyte-specific gene expression.

MAGI2 PTPRO H6PD

1.55e-052860325993318
Pubmed

Lowered expression of heparan sulfate/heparin biosynthesis enzyme N-deacetylase/n-sulfotransferase 1 results in increased sulfation of mast cell heparin.

NDST2 NDST4

1.75e-05460222049073
Pubmed

Regulated translation of heparan sulfate N-acetylglucosamine N-deacetylase/n-sulfotransferase isozymes by structured 5'-untranslated regions and internal ribosome entry sites.

NDST2 NDST4

1.75e-05460212070138
Pubmed

Mesenchymal cells with leukocyte and lymphendothelial characteristics in murine embryos.

PTPRC PROX1

1.75e-05460216502417
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FRAS1 FAT1 SZT2 RPS6KA2 ZDHHC5 FBRSL1 AMBRA1 ZER1 CHD8 ATG2A

1.79e-051105601035748872
Pubmed

Rewiring of RSK-PDZ Interactome by Linear Motif Phosphorylation.

MAGI2 SHROOM2 SNTB1

2.81e-053460330726710
Pubmed

Multiple isozymes of heparan sulfate/heparin GlcNAc N-deacetylase/GlcN N-sulfotransferase. Structure and activity of the fourth member, NDST4.

NDST2 NDST4

2.92e-05560211087757
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SZT2 FBRSL1 KIAA1549 AMBRA1 CHD8 SCAF11 ATG2A

3.48e-0552960714621295
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

FAT1 NF1 ZDHHC5 KIAA1549 NUMB FAM135A SNTB1

5.51e-0556960730639242
Pubmed

Sall1 plays pivotal roles for lens fiber cell differentiation in mouse.

PTPRC PROX1

6.11e-05760230929925
Pubmed

Coordinated lymphangiogenesis is critical in lymph node development and maturation.

PTPRC PROX1

6.11e-05760227623309
Pubmed

Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.

PTPRC PTPRO

6.11e-05760215978577
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MAGI2 UNC5A FRAS1 RIPOR2 TENM4 TET3

7.27e-0540760612693553
Pubmed

FGF signaling sustains the odontogenic fate of dental mesenchyme by suppressing β-catenin signaling.

NDST2 NDST4

8.14e-05860224067353
Pubmed

Syntrophins regulate alpha1D-adrenergic receptors through a PDZ domain-mediated interaction.

MAGI2 SNTB1

8.14e-05860216533813
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TRIM5

8.14e-05860210331952
Pubmed

Cellular phenotypes and spatio-temporal patterns of lymphatic vessel development in embryonic mouse hearts.

PTPRC PROX1

8.14e-05860222753134
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

MAGI2 NF1 OSBPL6 KIAA1549 NUMB GRIA3

9.83e-0543060632581705
Pubmed

Genetic epistasis between heparan sulfate and FGF-Ras signaling controls lens development.

NDST2 PROX1

1.05e-04960221536023
Pubmed

Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System.

PTPRC PROX1

1.05e-04960229768210
Pubmed

Expression of lymphatic endothelium-specific hyaluronan receptor LYVE-1 in the developing mouse kidney.

PTPRC PROX1

1.31e-041060221181199
Pubmed

Hyperactive KRAS/MAPK signaling disrupts normal lymphatic vessel architecture and function.

PTPRC PROX1

1.31e-041060237842094
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

TENM4 WDR11 FAM135A DNAH1

1.45e-0415360410718198
Pubmed

Genome-wide CRISPR screening reveals genetic modifiers of mutant EGFR dependence in human NSCLC.

NF1 ACRBP SOCS5 AMBRA1 CHD8

1.53e-0429360531741433
Pubmed

Developmental and regional expression of heparan sulfate sulfotransferase genes in the mouse brain.

NDST2 NDST4

1.59e-041160215944372
Pubmed

Absence of Nkx2-3 homeodomain transcription factor induces the formation of LYVE-1-positive endothelial cysts without lymphatic commitment in the spleen.

PTPRC PROX1

1.59e-041160221705651
Pubmed

A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature.

PTPRC PROX1

1.91e-041260236697821
Pubmed

Potential functions of embryonic cardiac macrophages in angiogenesis, lymphangiogenesis and extracellular matrix remodeling.

PTPRC PROX1

1.91e-041260233130914
Pubmed

Variant heparan sulfates synthesized in developing mouse brain differentially regulate FGF signaling.

NDST2 NDST4

1.91e-041260212460940
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

NUDT19 FRAS1 WDR11 ERAP2 ZDHHC5 KIAA1549 NUMB FAM135A LCMT2 SNTB1

2.12e-041487601033957083
Pubmed

Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development.

PTPRC PROX1

2.26e-041360222354871
Pubmed

Lens induction requires attenuation of ERK signaling by Nf1.

NF1 PROX1

2.26e-041360221233129
Pubmed

Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits.

PTPRC CHD8

2.26e-041360228402856
Pubmed

A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development.

PTPRC PROX1

3.03e-041560229773646
Pubmed

Brain-specific angiogenesis inhibitor-1 signaling, regulation, and enrichment in the postsynaptic density.

MAGI2 SNTB1

3.03e-041560223782696
Pubmed

Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction.

PTPRC PROX1

3.03e-041560229853539
Pubmed

cKit Lineage Hemogenic Endothelium-Derived Cells Contribute to Mesenteric Lymphatic Vessels.

PTPRC PROX1

3.46e-041660225772358
Pubmed

The Genetic Basis of Baculum Size and Shape Variation in Mice.

PTPRC RBL1

3.46e-041660226935419
Pubmed

Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax.

PTPRC PROX1

3.91e-041760221515254
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TBC1D4 PTPRC WDR11 DUSP4 ZDHHC5 KIAA1549 NUMB SNTB1

4.25e-04104960827880917
Pubmed

REST corepressors RCOR1 and RCOR2 and the repressor INSM1 regulate the proliferation-differentiation balance in the developing brain.

RIPOR2 PROX1

4.40e-041860228049845
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

FRAS1 GRIA3

4.40e-041860214730302
Pubmed

Deciphering the heterogeneity of the Lyve1+ perivascular macrophages in the mouse brain.

PTPRC PROX1

4.40e-041860236450771
Pubmed

Generalist genes analysis of DNA markers associated with mathematical ability and disability reveals shared influence across ages and abilities.

FRAS1 TENM4

4.40e-041860220602751
Pubmed

Evidence for distinct functions for human DNA repair factors hHR23A and hHR23B.

SZT2 UBA3

4.40e-041860216712842
Pubmed

Genes, plasticity and mental retardation.

NF1 GRIA3

4.91e-041960218329113
Pubmed

Lymph sacs are not required for the initiation of lymph node formation.

PTPRC PROX1

4.91e-041960219060331
Pubmed

Proteostasis is essential during cochlear development for neuron survival and hair cell polarity.

NF1 GRIA3

4.91e-041960231321879
Pubmed

Gene Expression by Mouse Inner Ear Hair Cells during Development.

PCDH15 PROX1

4.91e-041960225904789
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

RIPOR2 PTPRC SOCS5 TACC2 SHROOM2 FAM135A LCMT2 TRIM5

5.28e-04108460811544199
Pubmed

Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease.

MAGI2 SCAF11

5.45e-042060219668339
Pubmed

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.

AMBRA1 TRIM5

5.45e-042060225127057
Pubmed

Chromatin remodeling protein HELLS is critical for retinoblastoma tumor initiation and progression.

RBL1 PROX1

6.61e-042260232071286
Pubmed

NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development.

NDST2 NDST4

6.61e-042260219299468
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

TBC1D4 WDR11 AMBRA1 CHD8

7.02e-0423260425515538
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FBRSL1 KIAA1549 CHD8

7.21e-0410160310997877
Pubmed

YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells.

PTPRC PROX1

7.23e-042360231980640
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

WDR11 NDST2 PCDH15 TACC2 VWA2

7.52e-0441560516385451
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

FRAS1 WDR11 RBL1 FBRSL1 AMBRA1 CHD8

8.86e-0465060638777146
Pubmed

The candidate splicing factor Sfswap regulates growth and patterning of inner ear sensory organs.

NUMB PROX1

9.26e-042660224391519
Pubmed

Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation.

PTPRC PROX1

9.26e-042660220978081
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

ZDHHC5 KIAA1549 NUMB FAM135A

1.12e-0326360434702444
Pubmed

A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation.

PTPRC PROX1

1.15e-032960237160119
Pubmed

Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.

CYP1A2 FMO1

1.23e-033060220529763
Pubmed

Genome-wide association study of anthropometric traits and evidence of interactions with age and study year in Filipino women.

MAGI2 PCDH15

1.49e-033360220966902
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

MAGI2 TBC1D4 KIAA1549

1.49e-0313060312421765
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

WDR11 NUMB TACC2 FAM135A

1.50e-0328560434369648
Pubmed

Efficient isolation of novel mouse genes differentially expressed in early postimplantation embryos.

NF1 CHD8

1.58e-03346027490078
Pubmed

A genome-wide association study (GWAS) for bronchopulmonary dysplasia.

MAGI2 NDST4

1.58e-033460223897914
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WDR11 SOCS5 ZDHHC5 FAM135A LCMT2

1.61e-0349360515368895
Cytoband10q26

WDR11 TACC2

4.18e-042360210q26
GeneFamilyCadherin related

FAT1 PCDH15

5.73e-041738224
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRC PTPRO

8.81e-0421382813
GeneFamilySulfotransferases, membrane bound

NDST2 NDST4

2.73e-0337382763
GeneFamilyPDZ domain containing

MAGI2 SHROOM2 SNTB1

3.96e-031523831220
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 RIPOR2 RPS6KA2 PCDH15 NDST4 PROX1

2.61e-071966067af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FMO1 PTPRO DUSP4 NDST4 PROX1

8.96e-071306058bd038b0423960ffdc6c8b128c46a55386f9c58c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 FMO1 PTPRO NDST4 PROX1

1.94e-06152605fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellT_cells-Tph_and_Tfh|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TBC1D4 PTPRC DUSP4 ADGRG1 ITM2A

2.65e-06162605146058f2d60846376078916055d08f68562e3a7c
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 FMO1 PTPRO NDST4 PROX1

2.73e-061636058d17f44faf0549fe71a9a45f811f50d767275414
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 TBC1D4 SNTB1

3.97e-06176605327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 TBC1D4 SNTB1

4.68e-061826055e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 TBC1D4 SNTB1

4.80e-06183605738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 TBC1D4 SNTB1

4.80e-0618360592fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT1 TENM4 PCDH15 DNAH1

4.93e-061846052cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT1 TENM4 PCDH15 DNAH1

4.93e-06184605ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 FAT1 TENM4 PCDH15 DNAH1

4.93e-061846052b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRAS1 FAT1 PCDH15 NDST4 PROX1

5.20e-06186605310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 TBC1D4 SNTB1

5.62e-06189605904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RIPOR2 PTPRC ERAP2 DUSP4 ITM2A

6.06e-061926051b0138fd0bfdee266325751f8b2d163d91a71bf5
ToppCell(07)_Ionocytes|World / shred by cell type by condition

FMO1 TBC1D4 DUSP4 SNTB1 PROX1

7.22e-061996058194777d367405a7840787e977854b5c07e3bd6b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Tmem182|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FMO1 PTPRO NDST4 PROX1

2.38e-05124604690595d710b57b7cff8029a3bb06a8dd7e3c03c1
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP1A2 FRAS1 PCDH15 NDST4

4.39e-0514560496712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 PTPRO NDST4 PROX1

5.27e-051526048ff5a178a8f3550d89a003c0858820aab3773386
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGI2 PTPRC RPS6KA2 NDST4

5.41e-051536043b1b0cc8e9dd2b1484649789330713282ee44414
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT1 FMO1 NDST4 PROX1

5.98e-05157604516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellnormal-na-Lymphocytic_T-T4_reg-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

6.91e-0516360443887e7687fc6367efac0c1f56a9534b06f47b7f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FMO1 PTPRO NDST4 PROX1

7.08e-0516460408819970174a3eb4eee8e1e675075828665b845e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 SNTB1

7.08e-05164604382e42701779d12a7948690b3be72d06dd75c8b4
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 RPS6KA2 KIAA1549 FAM135A

8.90e-05174604f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellT_cells-Tph_and_Tfh|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

TBC1D4 DUSP4 ADGRG1 ITM2A

9.30e-0517660456c055488e34605d32562571a2fee621b47c9441
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PTPRO PCDH15 TACC2 PROX1

9.30e-0517660405ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell(1)_T_regulatory|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TBC1D4 PTPRC DUSP4 ITM2A

9.51e-051776045cda56b10df1ee8971ce8470d52062e01b703a4e
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

RIPOR2 PTPRC OTUD6A KIAA1549

9.72e-0517860434ec499d03cc198cfefa19a724d4c81974052f65
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

9.72e-0517860490dedb3cef9b01907b9f8eec64218d6d2072be1f
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBC1D4 RBL1 DUSP4 ITM2A

9.72e-05178604f94e306b9550f3d1b5de0bb806790c17823d439e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-T4_reg|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

9.72e-05178604d6312286bf6cc5b107ccd7adb583d9667d4e1d21
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

COL8A2 NF1 ATG2A ITM2A

9.93e-051796049d51318ac198a8801bd5c7031ebf2b0c74ffeeb6
ToppCellnormal_Lymph_Node-T/NK_cells-Exhausted_CD8+_T|normal_Lymph_Node / Location, Cell class and cell subclass

PTPRC DUSP4 ATG2A ITM2A

9.93e-051796043dc929a10381b7d86650c6cd8f354892fe1d93e7
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_4|COVID-19_Convalescent / Disease condition and Cell class

COL8A2 NF1 ATG2A ITM2A

9.93e-05179604366e4a31db9e80fd1770ac9f1ae148fefeb9f7df
ToppCellASK428-Immune-NK_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

RIPOR2 PTPRC ADGRG1 ITM2A

1.01e-04180604857d09446e3e6737e83d0f10bfda2ba282d5ba75
ToppCellControl-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

RIPOR2 TBC1D4 DUSP4 ITM2A

1.01e-0418060447036eee4c128fbb443d1fc767b4de5cced93f0e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FRAS1 RIPOR2 SNTB1

1.04e-041816049d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 RIPOR2 TBC1D4 SNTB1

1.04e-04181604071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellLA-17._Lymphocyte|LA / Chamber and Cluster_Paper

RIPOR2 PTPRC OTUD6A KIAA1549

1.04e-041816043fd9f805fa46141b0fa7023ee5d8688d338635d5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FAT1 RIPOR2 SNTB1

1.04e-041816046956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Treg|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RIPOR2 TBC1D4 PTPRC ITM2A

1.04e-041816043754970d62eea1d2522b11d977eea4362f90d21e
ToppCellControl-Lymphoid-T_Regulatory|Control / Disease state, Lineage and Cell class

RIPOR2 TBC1D4 DUSP4 ITM2A

1.06e-0418260431bb838cc2900f3c9da9f835d79d557a08abb928
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FRAS1 RIPOR2 SNTB1

1.06e-04182604eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCellwk_08-11-Mesenchymal-Chondrocyte-Resting_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

COL8A2 ITIH6 FAM135A ITM2A

1.06e-0418260400a148b1e499bf16325491536d187d4dd6b70c06
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRAS1 FAT1 FMO1 KIAA1549

1.08e-041836046878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

FAT1 RIPOR2 FMO1 KIAA1549

1.10e-0418460451ed1ebfdef45149541917c66cbacad87072e51f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 RIPOR2 TBC1D4 SNTB1

1.10e-04184604da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellIPF-Lymphoid-T_Regulatory|IPF / Disease state, Lineage and Cell class

RIPOR2 TBC1D4 DUSP4 ITM2A

1.13e-04185604221cbd09d94cc0947d0e3c1aa14716d17cb2068d
ToppCellIPF-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

RIPOR2 TBC1D4 DUSP4 ITM2A

1.13e-0418560477fbecdab10bacc005b1c7e22ca414cfecef13c1
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-Treg|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBC1D4 PTPRC DUSP4 ITM2A

1.13e-04185604c1a44b7eed72a673923a7c44d06f891f18aa5aad
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-CD4_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

RIPOR2 TBC1D4 PTPRC ITM2A

1.13e-0418560432f43ddc8a899827924834546db33928e353271b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 RIPOR2 TBC1D4 SNTB1

1.15e-041866045c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FRAS1 RIPOR2 SNTB1

1.15e-04186604f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FRAS1 NUMB ITM2A SNTB1

1.17e-04187604ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellmetastatic_Brain-T/NK_cells-Treg|metastatic_Brain / Location, Cell class and cell subclass

TBC1D4 PTPRC DUSP4 ITM2A

1.17e-041876041b88e1399809c50a0156096d9c82b1d9e58bb720
ToppCell367C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NDST2 OSBPL6 KIAA1549 ITM2A

1.17e-041876047d416693cb719df4197a11acc6b4e19171352515
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|tumor_Lung / Location, Cell class and cell subclass

RIPOR2 PTPRC ADGRG1 ATG2A

1.17e-04187604530839fb53bb285b22919fde6aa16ce1399615ef
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 FMO1 KIAA1549 NUMB

1.17e-041876049d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell367C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NDST2 OSBPL6 KIAA1549 ITM2A

1.17e-04187604b1341d272d9fc07c6f7590d6d398d7a5cf42240b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI2 FRAS1 RIPOR2 PROX1

1.17e-04187604c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRAS1 FAT1 PCDH15 PROX1

1.20e-041886040501a8aa850bd2e347020abd1cac4d8075738189
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO PCDH15 KIAA1549 GRIA3

1.20e-041886047471c194276161422326647f09022e94f3d1640c
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPRC DUSP4 ATG2A ITM2A

1.20e-041886042513ca0efa73c09a3406b99e2876982d78b173d7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO PCDH15 KIAA1549 GRIA3

1.20e-04188604053c251d3ddbeb866f34565aefca4535517b4387
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

1.20e-04188604e5c480b9a030536578f1cc91fb61738f752525b3
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 RPS6KA2 SHROOM2 DNAH1

1.22e-041896048e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell(1)_T_CD4_reg|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

TBC1D4 PTPRC DUSP4 ITM2A

1.22e-0418960428f28672fd260bb2a8d64152737a7242347c3174
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRAS1 FAT1 PCDH15 PROX1

1.22e-04189604f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell3'_v3-Lung-Lymphocytic_T_CD8-Tem/emra_CD8|Lung / Manually curated celltypes from each tissue

RIPOR2 PTPRC ADGRG1 ITM2A

1.22e-04189604f43bb9db7bb2d19c9849cd3ed892fe3e09e7dfe2
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIPOR2 RPS6KA2 SHROOM2 DNAH1

1.22e-04189604fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellnormal-na-Lymphocytic_T-T4_reg-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

1.25e-04190604d8c1998eb02d5105598608d4733b63978ffa3eb2
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TBC1D4 PTPRC DUSP4 ITM2A

1.25e-04190604b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCellASK428-Immune-NK_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

RIPOR2 PTPRC ADGRG1 ITM2A

1.25e-04190604d649f7e17c4227787465dfc02037f791ff85378b
ToppCellmetastatic_Lymph_Node-T/NK_cells-Treg|metastatic_Lymph_Node / Location, Cell class and cell subclass

TBC1D4 PTPRC DUSP4 ITM2A

1.25e-041906040523f1039b39a45a23f2f4444e5b47ed581fc4bb
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO PCDH15 KIAA1549 GRIA3

1.25e-041906049b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCellnormal-na-Lymphocytic_T-T4_reg|normal / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

1.25e-04190604b8897c3e0fe8bb7efaf6a3787104d454d81a4c92
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO PCDH15 KIAA1549 GRIA3

1.25e-04190604d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_CD8+_T|metastatic_Brain / Location, Cell class and cell subclass

PTPRC DUSP4 ATG2A ITM2A

1.27e-04191604b98367fdb56ccb335d61035e69cd43c61a7fa816
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPRC ADGRG1 ATG2A ITM2A

1.27e-04191604b2d0ea24970da09209da9d9dda76e30fbfe22917
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FAT1 RIPOR2 TBC1D4 SNTB1

1.27e-04191604d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-T4_reg-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TBC1D4 PTPRC DUSP4 ITM2A

1.27e-04191604c5e22df4a8741b8096cdd1618271fd48d6265846
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRAS1 FAT1 PCDH15 PROX1

1.27e-041916047b386512284dfaa0e95358b28ee82632ee965e64
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO PCDH15 KIAA1549 GRIA3

1.27e-04191604ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO PCDH15 KIAA1549 GRIA3

1.27e-04191604478e8341ee03b05501e2233e02cef5f97492c95d
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRAS1 FAT1 PCDH15 PROX1

1.27e-04191604fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RIPOR2 PTPRC NUMB TET3

1.27e-0419160447a2afc4102199b4bc76bd01b2967c8016186462
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Treg|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TBC1D4 PTPRC DUSP4 ITM2A

1.30e-04192604c550b49abd30234851e19f35ad5ab8aba44bd3b5
ToppCellnormal_Lymph_Node-T/NK_cells-Treg|normal_Lymph_Node / Location, Cell class and cell subclass

TBC1D4 PTPRC DUSP4 ITM2A

1.30e-04192604d2c2a98d331522a3ab7973bfaf4396ef4d684888
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT1 TENM4 NDST4 GRIA3

1.30e-0419260472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPRC ADGRG1 ATG2A ITM2A

1.30e-0419260401d01c9293f2439dc4c34c648273319c9beee5c7
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

PTPRC ADGRG1 ATG2A ITM2A

1.30e-041926040f8c63de26128694f4522f9f6d029e4628c890bc
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT1 RIPOR2 RPS6KA2 PCDH15

1.30e-0419260467d6230e32d446dcb12047fae2c3f1faa80dd720
ToppCellILEUM-inflamed-(1)_Tregs|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TBC1D4 PTPRC DUSP4 ITM2A

1.30e-041926041fe3417dfd1cf1758fd82c9ac13dbd88bdf0b548
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Treg|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TBC1D4 PTPRC DUSP4 ITM2A

1.30e-041926040deb6aa323e1de72ee8a2002449e523dd4f0bf5d
ToppCellT/NK_cells-CD8+_Effector_T_cell|World / Lineage and Cell class

PTPRC DUSP4 ATG2A ITM2A

1.33e-0419360479fa0f482cd98642b1d38835cda98622f21e5bd0
ToppCelltumor_Lung-T/NK_cells-Treg|tumor_Lung / Location, Cell class and cell subclass

TBC1D4 PTPRC DUSP4 ITM2A

1.33e-04193604675645fb2e8e75fedba2ab51f67200961bfd2436
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|367C / Donor, Lineage, Cell class and subclass (all cells)

PTPRC DUSP4 ATG2A ITM2A

1.33e-041936048f8d2006fb40a207c743cfd2e9a9f47c2bac1eea
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RIPOR2 PTPRC DUSP4 ITM2A

1.33e-04193604465061688bc09c6d8adc2f662a385dab8918ebbf
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-6_SST_MTHFD2P6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RIPOR2 RPS6KA2 PCDH15 NDST4

1.33e-041936048b77625bf3c87d39767fb391d1beaca4ab02342b
DrugSB 203580; Up 200; 1uM; MCF7; HT_HG-U133A

CYP1A2 TBC1D4 NF1 DUSP4 NDST2 NUMB ZER1

9.46e-072006076899_UP
DrugPancuronium bromide [15500-66-0]; Down 200; 5.4uM; MCF7; HT_HG-U133A

CYP1A2 TBC1D4 NDST2 NUMB ZER1 TRIM5

1.28e-051966067329_DN
DrugBenzylpenicillin sodium [69-57-8]; Up 200; 11.2uM; MCF7; HT_HG-U133A

FRAS1 NF1 RPS6KA2 NOX3 H6PD PROX1

1.32e-051976063577_UP
DrugD-cycloserine [68-41-7]; Down 200; 39.2uM; HL60; HT_HG-U133A

CYP1A2 NF1 RPS6KA2 AMBRA1 ZER1 SNTB1

1.32e-051976066139_DN
DrugChenodiol [474-25-9]; Down 200; 10.2uM; PC3; HT_HG-U133A

CYP1A2 NF1 SZT2 ERAP2 RBL1 RPS6KA2

1.36e-051986067310_DN
Diseasealpha wave measurement, electroencephalogram measurement

NOX3 DNAH1

1.69e-0410582EFO_0004357, EFO_0006870
DiseaseMacrocephaly

CHD8 TET3

2.06e-0411582C0221355
Diseasefish consumption measurement

NF1 TENM4 NOX3

2.76e-0464583EFO_0010139
Disease1,3,7-trimethylurate measurement

CYP1A2 FRAS1

3.92e-0415582EFO_0021172
Diseaseintellectual disability (implicated_via_orthology)

RBL1 NDST2 NDST4

4.40e-0475583DOID:1059 (implicated_via_orthology)
Diseaseintracerebral hemorrhage

ADGRG1 TRIM5

4.48e-0416582EFO_0005669
Diseasealcohol use disorder measurement

MAGI2 NF1 WDR11 ZDHHC5

8.40e-04214584EFO_0009458
Diseasemean reticulocyte volume

RIPOR2 TBC1D4 PTPRC RBL1 FBRSL1 ARMC2 RHNO1

9.42e-04799587EFO_0010701
DiseaseCerebral Astrocytoma

NF1 KIAA1549

1.11e-0325582C0750935
DiseaseIntracranial Astrocytoma

NF1 KIAA1549

1.11e-0325582C0750936
DiseasePilocytic Astrocytoma

NF1 KIAA1549

1.11e-0325582C0334583
DiseaseAstrocytoma

NF1 KIAA1549

1.11e-0325582C0004114
DiseaseJuvenile Pilocytic Astrocytoma

NF1 KIAA1549

1.11e-0325582C0280783
DiseaseDiffuse Astrocytoma

NF1 KIAA1549

1.11e-0325582C0280785
DiseaseGrade I Astrocytoma

NF1 KIAA1549

1.11e-0325582C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NF1 KIAA1549

1.11e-0325582C0205768
DiseaseMixed oligoastrocytoma

NF1 KIAA1549

1.11e-0325582C0547065
DiseaseChildhood Cerebral Astrocytoma

NF1 KIAA1549

1.11e-0325582C0338070
Diseasebrain cancer (implicated_via_orthology)

NUMB PROX1

1.20e-0326582DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

NF1 KIAA1549

1.20e-0326582C0334581
DiseaseProtoplasmic astrocytoma

NF1 KIAA1549

1.20e-0326582C0334580
DiseaseFibrillary Astrocytoma

NF1 KIAA1549

1.20e-0326582C0334582
DiseaseAnaplastic astrocytoma

NF1 KIAA1549

1.29e-0327582C0334579
Diseaseazoospermia (implicated_via_orthology)

NDST2 NDST4

1.29e-0327582DOID:14227 (implicated_via_orthology)
Diseaseprostate carcinoma

WDR11 DUSP4 PCDH15 FBRSL1 ADGRG1 SHROOM2 ARMC2

1.76e-03891587EFO_0001663
Diseaseaspartate aminotransferase measurement

PLB1 NF1 PTPRC WDR11 ERAP2 OSBPL6 TRIM5

1.91e-03904587EFO_0004736

Protein segments in the cluster

PeptideGeneStartEntry
DSPYFRHSSVSFFPS

FBRSL1

486

Q9HCM7
RHSSVSFFPSFPPAI

FBRSL1

491

Q9HCM7
LHFLEPSQFPSESEF

CHD8

991

Q9HCK8
SITFSHYPPATLDSF

C8orf86

136

Q6ZUL3
FHSESLSSNPSSFAP

ACRBP

256

Q8NEB7
NRPPSSFSLHASSFE

ARMC2

66

Q8NEN0
ATTPSFSFVQTEPFH

AMBRA1

336

Q9C0C7
SGPPDLATHFFTEFD

ATG2A

446

Q2TAZ0
FRHSSFLPFTIPHST

CYP1A2

376

P05177
SFHETFEVPTPSCSA

KCNJ9

321

Q92806
EVHTPFQASVDSFSP

KIAA1107

941

Q9UPP5
DFASSFFSTPPLELS

KIAA1549

621

Q9HCM3
HVDEFLPFFSNPETS

OTUD6A

181

Q7L8S5
PSLEPISFEESFFTF

FAT1

1351

Q14517
PTHDIFSFYVSDGTS

FRAS1

1926

Q86XX4
PALHRSSFPDSTEAF

MAGI2

721

Q86UL8
FSRTAFPSLPDTDDH

NUDT19

96

A8MXV4
ESKHTEPSFPESFAS

KIAA2026

976

Q5HYC2
PSSFATHPNTDLVFE

FAM135A

776

Q9P2D6
HTSFVTPSFPTDADV

GRIA3

121

P42263
FFPTPSNTTSDFLFE

NDST4

651

Q9H3R1
PRDASFHIFPSTSTA

OSBPL6

191

Q9BZF3
FHIFPSTSTAESSPA

OSBPL6

196

Q9BZF3
FSHDSPSVPTFIAVS

PTPRO

796

Q16827
SHTPTPVSLFRETFF

OTOP2

276

Q7RTS6
LSSDSSFCFPRPHFS

PCDH15

1656

Q96QU1
PTFSSFSSDFVKHLS

DNAH1

3581

Q9P2D7
AHATPAFTAVLTSPF

COL8A2

571

P25067
ESPSPFESFLKVFSF

FMO1

506

Q01740
SFPTTKTYFPHFDLS

HBA1;

36

P69905
LPSAASFTFSFHSPP

ADGRG1

151

Q9Y653
PSFSDSDPAAIIHDF

ITM2A

131

O43736
PSIFTFSSSVDGDPH

ITIH6

1071

Q6UXX5
SQFSVPSSYHFTEDP

ERAP2

36

Q6P179
KPDSFHSLTPTFAAV

H6PD

326

O95479
FSFPVSVGVHSAPSS

DUSP4

366

Q13115
PRTIFPTSTISFEHF

SCAF11

266

Q99590
TFPHYEASSATTSPF

NUMB

561

P49757
QSFSSVPEHFTLPDS

SZT2

511

Q5T011
FPHLTFESPQSSSSE

RHNO1

91

Q9BSD3
TSDPPSSQSFSFHRD

SNTB1

226

Q13884
HTAPVSPHSTFFDTF

SOCS5

236

O75159
SPHSTFFDTFDPSLV

SOCS5

241

O75159
PSDFHTADFTASEEP

RBL1

231

P28749
ATTGFTTSTFRHPFP

PROX1

471

Q92786
KFSDSHPELAASPFT

SHROOM2

121

Q13796
QPFFYETTPSLHSED

PLB1

281

Q6P1J6
HPFTLTSAPQEDFFS

NOX3

336

Q9HBY0
GTPETPTFKDHSFFR

RIPOR2

346

Q9Y4F9
SAFQDSSFHTPSVPF

TRIM5

411

Q9C035
FTHPDFEPSTESLQF

UBA3

51

Q8TBC4
PHESFFSLFSDPRST

ZER1

66

Q7Z7L7
SDFLPDTQLFPHFTE

TPRX1

341

Q8N7U7
FACHSTESSPDFTLP

TAS1R1

21

Q7RTX1
SSTPHLEFPLDSFST

VWA2

96

Q5GFL6
FFHAIISSSSEFPPQ

NF1

1346

P21359
FFLSLHPAVTSSFPS

NDST2

621

P52849
HPAVTSSFPSPSTFE

NDST2

626

P52849
TTEGKPSSFFPEDSF

TENM4

416

Q6N022
SPFRPPSHSFSAVFD

TACC2

2011

O95359
PEEHSSFAPDSSAFP

TET3

411

O43151
LPSLHTSFSAPSFTA

TBC1D4

696

O60343
LDSHLSFFASKPSPT

UNC5A

786

Q6ZN44
SFRSPTFGKSFHFDP

ZDHHC5

406

Q9C0B5
TLSHTLVFPSSEAFP

LCMT2

316

O60294
FAPPTSFSHFTDQEL

nan

151

Q8N1Y9
ILSFSFDPFDPSHLT

WDR11

161

Q9BZH6
PTHTTAFSPASTFER

PTPRC

51

P08575
FHFDPEFTARTPTDS

RPS6KA2

346

Q15349