Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RASGRF1 RASGRF2 MYCBP2 ARHGEF5 GMIP RGS12 ARHGEF15 ARHGEF10L ARHGAP4 TBC1D10B ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	9.25e-06	507	154	15	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RASGRF1 RASGRF2 MYCBP2 ARHGEF5 GMIP RGS12 ARHGEF15 ARHGEF10L ARHGAP4 TBC1D10B ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	9.25e-06	507	154	15	GO:0030695
GeneOntologyMolecularFunction	microtubule binding	MAP1A GAS2L3 MAP4 KIF26A APC2 CAMSAP3 TOGARAM1 KIFC2 TTBK2 DST MACF1	2.80e-05	308	154	11	GO:0008017
GeneOntologyMolecularFunction	tubulin binding	MAP1A GAS2L3 MAP4 KIF26A APC2 CAMSAP3 WIPF3 TOGARAM1 KIFC2 TTBK2 DST MACF1 GNAS	2.85e-05	428	154	13	GO:0015631
GeneOntologyMolecularFunction	GTPase activator activity	GMIP RGS12 ARHGEF15 ARHGEF10L ARHGAP4 TBC1D10B ARAP3 AGAP1 AGAP2 AGAP3	6.33e-05	279	154	10	GO:0005096
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	DUT HMGA1 NFATC4	5.40e-04	21	154	3	GO:0042975
GeneOntologyBiologicalProcess	activation of GTPase activity	RASGRF1 ARHGEF5 APC2 GMIP ARHGEF15 TBC1D10B AGAP1 AGAP2 AGAP3	1.22e-07	109	153	9	GO:0090630
GeneOntologyBiologicalProcess	positive regulation of GTPase activity	RASGRF1 ARHGEF5 APC2 GMIP ARHGEF15 TBC1D10B ARAP3 AGAP1 AGAP2 AGAP3	1.46e-05	244	153	10	GO:0043547
GeneOntologyBiologicalProcess	microtubule polymerization or depolymerization	MAP1A MAP4 APC2 CAMSAP3 TOGARAM1 NCKAP5L TTBK2 INPP5J	3.72e-05	168	153	8	GO:0031109
GeneOntologyBiologicalProcess	negative regulation of microtubule polymerization or depolymerization	MAP1A APC2 CAMSAP3 TTBK2 INPP5J	3.75e-05	51	153	5	GO:0031111
GeneOntologyBiologicalProcess	regulation of GTPase activity	RASGRF1 ARHGEF5 APC2 GMIP ARHGEF15 TBC1D10B ARAP3 PLXNC1 AGAP1 AGAP2 AGAP3	4.23e-05	335	153	11	GO:0043087
GeneOntologyBiologicalProcess	supramolecular fiber organization	CARMIL2 MAP1A GAS2L3 MAP4 ARHGEF5 COL27A1 APC2 SH3KBP1 CAMSAP3 WIPF3 TOGARAM1 NCKAP5L EMILIN1 ARHGEF15 ARHGEF10L TTBK2 LDB3 CST3 INPP5J	8.92e-05	957	153	19	GO:0097435
GeneOntologyBiologicalProcess	microtubule cytoskeleton organization	MAP1A GAS2L3 MAP4 APC2 CAMSAP3 CUL9 TOGARAM1 PARD3B NCKAP5L KIFC2 TTBK2 DST CCDC120 SAC3D1 CEP131 INPP5J	9.25e-05	720	153	16	GO:0000226
GeneOntologyBiologicalProcess	microtubule depolymerization	MAP1A APC2 CAMSAP3 NCKAP5L TTBK2	1.31e-04	66	153	5	GO:0007019
GeneOntologyBiologicalProcess	regulation of microtubule polymerization or depolymerization	MAP1A APC2 CAMSAP3 TOGARAM1 TTBK2 INPP5J	1.55e-04	108	153	6	GO:0031110
GeneOntologyBiologicalProcess	negative regulation of synapse maturation	ARHGEF15 NFATC4	1.63e-04	3	153	2	GO:2000297
GeneOntologyBiologicalProcess	negative regulation of microtubule depolymerization	MAP1A APC2 CAMSAP3 TTBK2	1.77e-04	38	153	4	GO:0007026
GeneOntologyBiologicalProcess	microtubule-based protein transport	MAP1A CAMSAP3 CEP131	2.52e-04	17	153	3	GO:0099118
GeneOntologyBiologicalProcess	protein transport along microtubule	MAP1A CAMSAP3 CEP131	2.52e-04	17	153	3	GO:0098840
GeneOntologyBiologicalProcess	regulation of microtubule depolymerization	MAP1A APC2 CAMSAP3 TTBK2	2.62e-04	42	153	4	GO:0031114
GeneOntologyCellularComponent	microtubule	MAP1A GAS2L3 MAP4 KIF26A APC2 CAMSAP3 AKNA TOGARAM1 NCKAP5L KIFC2 ARHGAP4 DST MACF1 CEP170B	4.47e-05	533	155	14	GO:0005874
Domain	GAR	GAS2L3 DST MACF1	9.58e-06	6	148	3	PS51460
Domain	GAS2	GAS2L3 DST MACF1	9.58e-06	6	148	3	PF02187
Domain	-	GAS2L3 DST MACF1	9.58e-06	6	148	3	3.30.920.20
Domain	GAS_dom	GAS2L3 DST MACF1	9.58e-06	6	148	3	IPR003108
Domain	GAS2	GAS2L3 DST MACF1	9.58e-06	6	148	3	SM00243
Domain	CH	GAS2L3 CAMSAP3 SPECC1 MICALL1 DST MACF1	1.93e-05	70	148	6	PF00307
Domain	CH	GAS2L3 CAMSAP3 SPECC1 MICALL1 DST MACF1	2.46e-05	73	148	6	PS50021
Domain	CH-domain	GAS2L3 CAMSAP3 SPECC1 MICALL1 DST MACF1	2.87e-05	75	148	6	IPR001715
Domain	PH_dom-like	RASGRF1 RASGRF2 ARHGEF5 RGS12 SH2B1 ARHGEF15 ARHGEF10L ARAP3 RALGPS1 EPB41L1 AGAP1 AGAP2 AGAP3	3.54e-05	426	148	13	IPR011993
Domain	-	RASGRF1 RASGRF2 ARHGEF5 RGS12 SH2B1 ARHGEF10L ARAP3 RALGPS1 EPB41L1 AGAP1 AGAP2 AGAP3	6.76e-05	391	148	12	2.30.29.30
Domain	ArfGap	ARAP3 AGAP1 AGAP2 AGAP3	7.71e-05	29	148	4	SM00105
Domain	ARFGAP	ARAP3 AGAP1 AGAP2 AGAP3	7.71e-05	29	148	4	PS50115
Domain	ArfGap	ARAP3 AGAP1 AGAP2 AGAP3	7.71e-05	29	148	4	PF01412
Domain	ArfGAP	ARAP3 AGAP1 AGAP2 AGAP3	7.71e-05	29	148	4	IPR001164
Domain	PH	RASGRF1 RASGRF2 ARHGEF5 SH2B1 ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	8.97e-05	229	148	9	PF00169
Domain	MIRO-like	AGAP1 AGAP2 AGAP3	1.32e-04	13	148	3	IPR013684
Domain	Roc	AGAP1 AGAP2 AGAP3	1.32e-04	13	148	3	PF08477
Domain	DH_1	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	1.42e-04	63	148	5	PS00741
Domain	CH	GAS2L3 SPECC1 MICALL1 DST MACF1	1.65e-04	65	148	5	SM00033
Domain	RhoGEF	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	2.04e-04	68	148	5	SM00325
Domain	RhoGEF	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	2.34e-04	70	148	5	PF00621
Domain	DH_2	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	2.34e-04	70	148	5	PS50010
Domain	-	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	2.50e-04	71	148	5	1.20.900.10
Domain	DH-domain	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	2.50e-04	71	148	5	IPR000219
Domain	-	GAS2L3 SPECC1 MICALL1 DST MACF1	2.50e-04	71	148	5	1.10.418.10
Domain	SH3	MPP3 AMPH TSPOAP1 ARHGEF5 SH3KBP1 ARHGAP4 DST MACF1	3.31e-04	216	148	8	PS50002
Domain	SH3_domain	MPP3 AMPH TSPOAP1 ARHGEF5 SH3KBP1 ARHGAP4 DST MACF1	3.75e-04	220	148	8	IPR001452
Domain	PH	RASGRF1 RASGRF2 ARHGEF5 SH2B1 ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	3.81e-04	278	148	9	SM00233
Domain	PH_DOMAIN	RASGRF1 RASGRF2 ARHGEF5 SH2B1 ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	3.91e-04	279	148	9	PS50003
Domain	PH_domain	RASGRF1 RASGRF2 ARHGEF5 SH2B1 ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	4.01e-04	280	148	9	IPR001849
Domain	SH3_2	MPP3 AMPH TSPOAP1 ARHGEF5 SH3KBP1	6.07e-04	86	148	5	PF07653
Domain	SH3_2	MPP3 AMPH TSPOAP1 ARHGEF5 SH3KBP1	6.07e-04	86	148	5	IPR011511
Domain	FYrich_C	KMT2B KMT2D	6.14e-04	5	148	2	IPR003889
Domain	FYrich_N	KMT2B KMT2D	6.14e-04	5	148	2	IPR003888
Domain	FYRC	KMT2B KMT2D	6.14e-04	5	148	2	SM00542
Domain	FYRN	KMT2B KMT2D	6.14e-04	5	148	2	SM00541
Domain	FYRN	KMT2B KMT2D	6.14e-04	5	148	2	PF05964
Domain	FYRC	KMT2B KMT2D	6.14e-04	5	148	2	PF05965
Domain	FYRC	KMT2B KMT2D	6.14e-04	5	148	2	PS51543
Domain	FYRN	KMT2B KMT2D	6.14e-04	5	148	2	PS51542
Domain	EPHD	KMT2B KMT2D MLLT6	6.72e-04	22	148	3	PS51805
Domain	-	DST MACF1	9.16e-04	6	148	2	3.90.1290.10
Domain	F_BAR	GMIP FCHO2 ARHGAP4	9.87e-04	25	148	3	IPR031160
Domain	F_BAR	GMIP FCHO2 ARHGAP4	9.87e-04	25	148	3	PS51741
Domain	RASGEF	RASGRF1 RASGRF2 RALGPS1	1.11e-03	26	148	3	PS00720
Domain	AT_hook	KMT2B HMGA1 SCML4	1.24e-03	27	148	3	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2B HMGA1 SCML4	1.24e-03	27	148	3	IPR017956
Domain	APC_su10/DOC_dom	MYCBP2 CUL9	1.28e-03	7	148	2	IPR004939
Domain	Plectin	DST MACF1	1.28e-03	7	148	2	PF00681
Domain	DOC	MYCBP2 CUL9	1.28e-03	7	148	2	PS51284
Domain	ANAPC10	MYCBP2 CUL9	1.28e-03	7	148	2	PF03256
Domain	Plectin_repeat	DST MACF1	1.28e-03	7	148	2	IPR001101
Domain	APC10	MYCBP2 CUL9	1.28e-03	7	148	2	SM01337
Domain	PLEC	DST MACF1	1.28e-03	7	148	2	SM00250
Domain	RASGEF_CAT	RASGRF1 RASGRF2 RALGPS1	1.53e-03	29	148	3	PS50009
Domain	RasGEF	RASGRF1 RASGRF2 RALGPS1	1.69e-03	30	148	3	PF00617
Domain	-	RASGRF1 RASGRF2 RALGPS1	1.69e-03	30	148	3	1.10.840.10
Domain	RASGEF_cat_dom	RASGRF1 RASGRF2 RALGPS1	1.69e-03	30	148	3	IPR001895
Domain	RasGEF	RASGRF1 RASGRF2 RALGPS1	1.69e-03	30	148	3	SM00147
Domain	Ras_GEF_dom	RASGRF1 RASGRF2 RALGPS1	1.69e-03	30	148	3	IPR023578
Domain	fn3	BOC TSPOAP1 SPEG VWA1 FNDC1 FSD1L	1.86e-03	162	148	6	PF00041
Domain	-	ZNF185 CRIP3 MICALL1 LDB3	2.31e-03	70	148	4	2.10.110.10
Domain	LIM	ZNF185 CRIP3 MICALL1 LDB3	2.44e-03	71	148	4	SM00132
Domain	Znf_LIM	ZNF185 CRIP3 MICALL1 LDB3	2.44e-03	71	148	4	IPR001781
Domain	LIM_DOMAIN_1	ZNF185 CRIP3 MICALL1 LDB3	2.44e-03	71	148	4	PS00478
Domain	LIM_DOMAIN_2	ZNF185 CRIP3 MICALL1 LDB3	2.44e-03	71	148	4	PS50023
Pathway	PID_RHOA_REG_PATHWAY	ARHGEF5 ARHGEF15 ARHGEF10L ARHGAP4 ARAP3	2.24e-05	46	105	5	M68
Pathway	REACTOME_CDC42_GTPASE_CYCLE	RASGRF2 ARHGEF5 GMIP ARHGEF15 ARHGAP4 ARAP3	7.08e-05	94	105	6	MM15598
Pathway	REACTOME_RHOA_GTPASE_CYCLE	RASGRF2 ARHGEF5 GMIP ARHGEF15 ARHGEF10L ARHGAP4 ARAP3	9.07e-05	142	105	7	MM15576
Pathway	REACTOME_RHOA_GTPASE_CYCLE	RASGRF2 ARHGEF5 GMIP ARHGEF15 ARHGEF10L ARHGAP4 ARAP3	1.23e-04	149	105	7	M41805
Pathway	REACTOME_RHO_GTPASE_CYCLE	RASGRF2 ARHGEF5 WIPF3 GMIP ARHGEF15 ARHGEF10L ZNF512B ARHGAP4 DST ARAP3 RBMX SPEN	1.28e-04	450	105	12	M27078
Pathway	REACTOME_CDC42_GTPASE_CYCLE	RASGRF2 ARHGEF5 WIPF3 GMIP ARHGEF15 ARHGAP4 ARAP3	1.57e-04	155	105	7	M41808
Pathway	REACTOME_RHO_GTPASE_CYCLE	RASGRF2 ARHGEF5 GMIP ARHGEF15 ARHGEF10L ZNF512B ARHGAP4 DST ARAP3 RBMX SPEN	4.22e-04	439	105	11	MM15595
Pathway	REACTOME_RAC1_GTPASE_CYCLE	RASGRF2 ARHGEF5 WIPF3 GMIP ARHGEF15 ARHGAP4 ARAP3	4.47e-04	184	105	7	M41809
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	MPP3 CRYBG2 ANKS6 KMT2B MYCBP2 KIF26A SPEG AKNA C15orf39 CUL9 FHIP1B KIFC2 ARHGEF10L C6orf132 MICALL1 PKMYT1 SCAF1 NCOR2 KMT2D DST ARAP3 TULP4 RALGPS1 BRD4 SAC3D1 MLLT6 CEP131 WDR90 SNAPC4 MBD5 SPEN CEP170B SOWAHB AGAP3	1.04e-18	1105	160	34	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ITCH CARMIL2 TTC28 MYCBP2 MAP4 ARHGEF5 CAMSAP3 PARD3B KIAA1191 NCKAP5L SPECC1 RGS12 C6orf132 MICALL1 USP31 TBC1D10B BMPR2 DST BRD4 MACF1 CEP131 GNAS DCLK1 CEP170B EPB41L1 AGAP3	3.03e-14	861	160	26	36931259
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	MAP1A RASGRF1 MYCBP2 MAP4 WDR7 SH3KBP1 CAMSAP3 HCN2 SPECC1 BMPR2 DST AJM1 MACF1 PRRC2A DCLK1 CEP170B EPB41L1 AGAP2	4.68e-14	347	160	18	17114649
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAP1A TCOF1 TSPOAP1 ARHGEF5 APC2 FAM186B SH2B1 C6orf132 NCOR2 LARP4B TULP4 ATXN2 NFATC4 MLLT6 WDR90 MGA SPEN	1.84e-11	430	160	17	35044719
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ITCH MAP1A TTC28 TCOF1 ATXN7L1 CUL9 ZC3H18 NCKAP5L FBXL6 ZNF512B ARHGAP4 SCAF1 MSH6 NCOR2 TBC1D10B LARP4B BCL11B BRD4 FOXL2NB MACF1 TAF4B MGA IRX2 CEP170B AGAP3	6.36e-11	1116	160	25	31753913
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ITCH TCOF1 PRR36 MYCBP2 WDR7 APC2 SH3KBP1 CAMSAP3 HCN2 CCDC177 NCOR2 BCL11B DST ATXN2 MACF1 CEP131 MGA PRRC2A GOLGA1 DCLK1 CEP170B EPB41L1 AGAP2	1.15e-10	963	160	23	28671696
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	MAP1A MAP4 HMGA1 NCKAP5L NCOR2 KMT2D RBMX CEP131 MGA SPEN CEP170B	1.05e-09	184	160	11	32908313
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	KMT2B TCOF1 MYCBP2 MAP4 CAMSAP3 ZC3H18 HMGA1 MICALL1 SCAF1 MSH6 NCOR2 TBC1D10B KMT2D RBMX BRD4 SAC3D1 SNAPC4 SPEN PRRC2A	3.49e-09	774	160	19	15302935
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	AMPH CARMIL2 MAP1A PRR36 MAP4 WDR7 SH3KBP1 ZNF185 CAMSAP3 CCDC177 SPECC1 ARCN1 USP31 DST AJM1 RBMX SORCS2 MACF1 PRRC2A DCLK1 CEP170B EPB41L1 AGAP2 AGAP3	4.43e-08	1431	160	24	37142655
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	AMPH MAP1A WDR7 CAMSAP3 MACF1 GNAS DCLK1 CEP170B EPB41L1 AGAP1 AGAP2	8.43e-08	281	160	11	28706196
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	APC2 CAMSAP3 FCHO2 HCN2 CCDC177 SPECC1 TBC1D10B MACF1 CEP170B EPB41L1 AGAP1 AGAP2 AGAP3	1.12e-07	430	160	13	32581705
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RASGRF1 MYCBP2 MAP4 TOGARAM1 ZC3H18 HMGA1 SCAF1 DCAF10 RBMX MACF1 SPEN PRRC2A	1.27e-07	361	160	12	26167880
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	AMPH MAP1A MYCBP2 MAP4 TSPOAP1 NACA SH3KBP1 CAMSAP3 HMGA1 NFS1 ARCN1 LARP4B AJM1 MACF1 CEP131 DCLK1 CEP170B EPB41L1 AGAP2 AGAP3	3.21e-07	1139	160	20	36417873
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	KMT2B MAP4 SH3KBP1 CUL9 NFS1 HCN2 KIFC2 TULP4 BRD4 KCNN1 SPEN	4.07e-07	329	160	11	17474147
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MAP1A TTC28 TCOF1 C15orf39 CUL9 ZC3H18 NCKAP5L NCOR2 PPP4R2 MACF1 CEP131 GNAS SPEN CEP170B	6.43e-07	588	160	14	38580884
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	TCOF1 MAP4 CAMSAP3 FCHO2 MSH6 LARP4B RBMX CEP131 SPEN CDCA5 PRRC2A EPB41L1 AGAP3	6.61e-07	503	160	13	16964243
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	CEBPD KMT2B MYCBP2 MAP4 C15orf39 HMGA1 TGIF1 MSH6 NCOR2 KMT2D ATXN2 PPP4R2 RBMX BRD4 SUGP1 MLLT6 SPEN CDCA5 PRRC2A	8.60e-07	1103	160	19	34189442
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	RASGRF2 PRR36 ARHGEF5 NACA SH3KBP1 DUT CAMSAP3 GMIP ARHGEF15 ARCN1 ARHGEF10L ARHGAP4 ARAP3 MGA CDCA5 PRRC2A AGAP3	1.24e-06	916	160	17	32203420
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MAP1A SPEG AJM1 MACF1 PRRC2A DCLK1 CEP170B EPB41L1 AGAP2	1.36e-06	231	160	9	16452087
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CABLES2 ITCH MYCBP2 MAP4 ATXN7L1 CAMSAP3 PARD3B ZNF767P SH2B1 NCOR2 BMPR2 TULP4 ATXN2 RALGPS1 MACF1 GNAS MBD5 PRDM15 CEP170B EPB41L1 AGAP1 AGAP3	1.43e-06	1489	160	22	28611215
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	KMT2B MAP4 NACA CAMSAP3 ZNF767P SPECC1 C6orf132 FBXL6 SCAF1 MSH6 LARP4B DST ATXN2 MACF1 CEP131 SPEN PRRC2A DCLK1 CEP170B EPB41L1 AGAP1 AGAP3	1.56e-06	1497	160	22	31527615
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ITCH TTC28 TCOF1 MYCBP2 APC2 CUL9 ADAMTS8 SPECC1 SH2B1 ARCN1 ZNF512B RNF123 DST KCNN1 MACF1 PRRC2A DCLK1 AGAP1 AGAP2 AGAP3	2.06e-06	1285	160	20	35914814
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	MAP4 SH3KBP1 ZNF185 SPECC1 C6orf132 MICALL1 TBC1D10B BMPR2 DST MACF1 CCDC120 JPT1 EPB41L1	2.39e-06	565	160	13	25468996
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TTC28 ATXN7L1 CUL9 SH2B1 DST MACF1 MBD5	2.51e-06	130	160	7	12421765
Pubmed	Human transcription factor protein interaction networks.	KMT2B ATXN7L1 NACA SH3KBP1 C15orf39 CUL9 ZC3H18 ZNF512B NCOR2 LARP4B KMT2D MIDN DST ATXN2 NFATC4 SUGP1 MLLT6 CEP131 MGA SPEN PRRC2A	2.75e-06	1429	160	21	35140242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TTC28 WDR7 TSPOAP1 SPEG CUL9 FHIP1B USP31 MACF1 SPEN CEP170B EPB41L1	3.22e-06	407	160	11	12693553
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KMT2B TTC28 MYCBP2 CAMSAP3 C15orf39 NCOR2 KMT2D DST BRD4 CEP131 MGA	4.15e-06	418	160	11	34709266
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	CABLES2 ITCH PARD3B FCHO2 SPECC1 USP31 TBC1D10B DST MACF1 EPB41L1 AGAP1	4.44e-06	421	160	11	36976175
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GAS2L3 TCOF1 MYCBP2 MAP4 NACA HMGA1 SPECC1 ARCN1 ZNF512B SCAF1 DST RBMX MACF1 CEP131 GNAS MGA SPEN	5.48e-06	1024	160	17	24711643
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYCBP2 DUSP2 CAMSAP3 HMGA1 FCHO2 NCKAP5L ZNF512B USP31 MSH6 NCOR2 TBC1D10B KMT2D ATXN2 PPP4R2 CEP131 PRRC2A EPB41L1	7.51e-06	1049	160	17	27880917
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP1 AGAP2 AGAP3	7.87e-06	9	160	3	12640130
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TCOF1 ZC3H18 ZNF512B BCL11B BRD4 SPEN	8.54e-06	103	160	6	32744500
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KMT2B TTC28 TCOF1 MYCBP2 MAP4 ARCN1 MSH6 KMT2D BRD4 MGA SPEN PRRC2A	9.87e-06	549	160	12	38280479
Pubmed	High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.	ANKS6 MYCBP2 CAMSAP3 C15orf39 ZC3H18 C6orf132 CCDC120 DCLK1 AGAP3	1.36e-05	307	160	9	37499664
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ANKS6 ITCH CARMIL2 FCHO2 SPECC1 RGS12 MICALL1 TBC1D10B SLITRK2 PLXNC1 EPB41L1 AGAP1	1.41e-05	569	160	12	30639242
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	COL27A1 TOGARAM1 KIAA1191 SH2B1 ARHGEF15 LARP4B LDB3 TULP4 MACF1 MBD5 MGA	1.94e-05	493	160	11	15368895
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	AMPH TCOF1 MAP4 NACA GMIP CEP41 DCLK1 EPB41L1	1.98e-05	246	160	8	15345747
Pubmed	RASGRF2 controls nuclear migration in postnatal retinal cone photoreceptors.	RASGRF1 RASGRF2	2.10e-05	2	160	2	26743081
Pubmed	A model of partnership co-opted by the homeodomain protein TGIF and the Itch/AIP4 ubiquitin ligase for effective execution of TNF-alpha cytotoxicity.	ITCH TGIF1	2.10e-05	2	160	2	20064471
Pubmed	The PTH-Gαs-protein kinase A cascade controls αNAC localization to regulate bone mass.	NACA GNAS	2.10e-05	2	160	2	24550008
Pubmed	AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton.	AGAP1 AGAP2	2.10e-05	2	160	2	12388557
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	2.10e-05	2	160	2	11002341
Pubmed	RBMX is a component of the centromere noncoding RNP complex involved in cohesion regulation.	RBMX CDCA5	2.10e-05	2	160	2	29383807
Pubmed	Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma.	MEF2B KMT2D	2.10e-05	2	160	2	21796119
Pubmed	The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with Actin Filaments to Coordinate Their Dynamics.	CAMSAP3 MACF1	2.10e-05	2	160	2	27693509
Pubmed	Distinct roles for Ras-guanine nucleotide-releasing factor 1 (Ras-GRF1) and Ras-GRF2 in the induction of long-term potentiation and long-term depression.	RASGRF1 RASGRF2	2.10e-05	2	160	2	16467520
Pubmed	Kabuki syndrome stem cell models reveal locus specificity of histone methyltransferase 2D (KMT2D/MLL4).	KMT2B KMT2D	2.10e-05	2	160	2	35640156
Pubmed	A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth.	ARHGEF5 ARHGEF15	2.10e-05	2	160	2	28185854
Pubmed	Ras-GRF2 regulates nestin-positive stem cell density and onset of differentiation during adult neurogenesis in the mouse dentate gyrus.	RASGRF1 RASGRF2	2.10e-05	2	160	2	28966131
Pubmed	The environment versus genetics in controlling the contribution of MAP kinases to synaptic plasticity.	RASGRF1 RASGRF2	2.10e-05	2	160	2	17141611
Pubmed	The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3.	AGAP1 AGAP2	2.10e-05	2	160	2	16079295
Pubmed	Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.	CAMSAP3 MACF1	2.10e-05	2	160	2	27802168
Pubmed	Comparison of methylation episignatures in KMT2B- and KMT2D-related human disorders.	KMT2B KMT2D	2.10e-05	2	160	2	35506254
Pubmed	The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice.	RASGRF1 RASGRF2	2.10e-05	2	160	2	31182637
Pubmed	Transgenerational rescue of a genetic defect in long-term potentiation and memory formation by juvenile enrichment.	RASGRF1 RASGRF2	2.10e-05	2	160	2	19193896
Pubmed	Activation of H-Ras in the endoplasmic reticulum by the RasGRF family guanine nucleotide exchange factors.	RASGRF1 RASGRF2	2.10e-05	2	160	2	14749369
Pubmed	A murine CDC25/ras-GRF-related protein implicated in Ras regulation.	RASGRF1 RASGRF2	2.10e-05	2	160	2	8293576
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	KMT2B ZC3H18 SPECC1 SCAF1 TBC1D10B KMT2D SUGP1 SPEN	2.29e-05	251	160	8	31076518
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MAP1A MYCBP2 RBMX MACF1 MGA	2.75e-05	76	160	5	27542412
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	MAP4 DUT ARHGEF15 NCOR2 MACF1 SPEN	3.66e-05	133	160	6	15604093
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF26A NACA AKNA ARHGEF10L MICALL1 ZNF512B ARHGAP4 DST RALGPS1 WDR90 AGAP1	3.68e-05	529	160	11	14621295
Pubmed	A protein interaction landscape of breast cancer.	TTC28 TCOF1 SPCS1 ZNF185 CUL9 ZC3H18 SPECC1 MSH6 DST AEBP2 MACF1 EPB41L1	4.04e-05	634	160	12	34591612
Pubmed	Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2.	APC2 BCL11B DCLK1	4.17e-05	15	160	3	22573669
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	TTC28 ZNF185 CAMSAP3 PARD3B KIAA1191 FCHO2 FHIP1B NCKAP5L RGS12 ARCN1 MICALL1 CEP41 MGA CEP170B	4.34e-05	853	160	14	28718761
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	MAP4 PAXX ZC3H18 MSH6 BRD4 SUGP1 MGA SPEN	5.34e-05	283	160	8	30585729
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	TCOF1 MYCBP2 MAP4 CUL9 ZC3H18 MSH6 LARP4B DST RBMX MACF1 SPEN PRRC2A	5.36e-05	653	160	12	22586326
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MAP1A TTC28 KIAA1191 DST MACF1 CEP131 CEP170B	5.49e-05	209	160	7	36779422
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	TCOF1 MAP4 CAMSAP3 ZC3H18 NFS1 MSH6 NCOR2 LARP4B DCAF10 PPP4R2 GNAS PRRC2A	5.52e-05	655	160	12	35819319
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	GAS2L3 MAP4 SPECC1 ARCN1 MSH6 BCL11B ATXN2 SUGP1 PRRC2A	5.83e-05	370	160	9	22922362
Pubmed	Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis.	KIF26A BCL11B	6.29e-05	3	160	2	36228617
Pubmed	RasGRF suppresses Cdc42-mediated tumour cell movement, cytoskeletal dynamics and transformation.	RASGRF1 RASGRF2	6.29e-05	3	160	2	21685891
Pubmed	Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.	KMT2B KMT2D	6.29e-05	3	160	2	32544095
Pubmed	Pike. A nuclear gtpase that enhances PI3kinase activity and is regulated by protein 4.1N.	EPB41L1 AGAP2	6.29e-05	3	160	2	11136977
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	6.29e-05	3	160	2	12399109
Pubmed	The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.	KMT2B KMT2D	6.29e-05	3	160	2	23358417
Pubmed	Structural insights into the recruitment of SMRT by the corepressor SHARP under phosphorylative regulation.	NCOR2 SPEN	6.29e-05	3	160	2	24268649
Pubmed	Targeted disruption of Ras-Grf2 shows its dispensability for mouse growth and development.	RASGRF1 RASGRF2	6.29e-05	3	160	2	11909944
Pubmed	In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target Slug.	HMGA1 BMPR2	6.29e-05	3	160	2	27045138
Pubmed	HIC1 controls cellular- and HIV-1- gene transcription via interactions with CTIP2 and HMGA1.	HMGA1 BCL11B	6.29e-05	3	160	2	27725726
Pubmed	Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer's-like impairment in mice.	ARHGEF5 ARHGEF15	6.29e-05	3	160	2	28346227
Pubmed	Developmentally regulated role for Ras-GRFs in coupling NMDA glutamate receptors to Ras, Erk and CREB.	RASGRF1 RASGRF2	6.29e-05	3	160	2	15029245
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	PARD3B MICALL1 TBC1D10B BMPR2 DST GNAS EPB41L1 AGAP1 AGAP3	6.73e-05	377	160	9	38117590
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	CRYBG2 TTC28 PARD3B ZC3H18 HMGA1 LARP4B KMT2D BRD4 AEBP2 SPEN	6.80e-05	469	160	10	27634302
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ATXN7L1 ZNF512B MSH6 RBMX BRD4 SUGP1 MGA	8.02e-05	222	160	7	37071664
Pubmed	Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance.	MAP1A TCOF1 MAP4 SH3KBP1 PPP4R2 JPT1 MGA	8.96e-05	226	160	7	31452512
Pubmed	mTOR Inhibition via Rapamycin Treatment Partially Reverts the Deficit in Energy Metabolism Caused by FH Loss in RPE Cells.	ITCH MAP1A NCKAP5L DST MGA	9.31e-05	98	160	5	34943047
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	ANKS6 TCOF1 C15orf39 CAVIN3 GMIP KIAA1191 FCHO2 NCKAP5L ARCN1 LARP4B ARAP3 CEP41 SUGP1 GNAS AGAP1	9.62e-05	1038	160	15	26673895
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	KMT2B MYCBP2 ZNF689 SPECC1 FBXL6 ZNF512B KMT2D AEBP2 MBD5 MGA	1.06e-04	495	160	10	27705803
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	MAP1A COL27A1 CUL9 ZC3H18 HMGA1 EMILIN1 MSH6 MACF1 TAF4B PRRC2A	1.08e-04	496	160	10	31343991
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MAP1A TCOF1 MAP4 NACA DUT HMGA1 ARCN1 ZNF512B MSH6 DST SUGP1 MACF1 JPT1 PRRC2A	1.13e-04	934	160	14	33916271
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	TTC28 TCOF1 MAP4 ZC3H18 FCHO2 ARCN1 MICALL1 TBC1D10B DST MACF1 PRRC2A EPB41L1	1.15e-04	708	160	12	39231216
Pubmed	Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	KIF26A ATXN7L1 ZNF512B USP31 MACF1	1.18e-04	103	160	5	10574462
Pubmed	Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.	KMT2B KMT2D	1.25e-04	4	160	2	19221051
Pubmed	MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.	KMT2B KMT2D	1.25e-04	4	160	2	20808952
Pubmed	Mutations in Mll2, an H3K4 methyltransferase, result in insulin resistance and impaired glucose tolerance in mice.	KMT2B KMT2D	1.25e-04	4	160	2	23826075
Pubmed	Interaction of the Epstein-Barr virus mRNA export factor EB2 with human Spen proteins SHARP, OTT1, and a novel member of the family, OTT3, links Spen proteins with splicing regulation and mRNA export.	NCOR2 SPEN	1.25e-04	4	160	2	16129689
Pubmed	DUB3 Promotes BET Inhibitor Resistance and Cancer Progression by Deubiquitinating BRD4.	NCOR2 BRD4	1.25e-04	4	160	2	30057199
Pubmed	A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.	KMT2B KMT2D	1.25e-04	4	160	2	23129768
Pubmed	Structural and spatial determinants regulating TC21 activation by RasGRF family nucleotide exchange factors.	RASGRF1 RASGRF2	1.25e-04	4	160	2	19692568
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	1.25e-04	4	160	2	8954775
Interaction	MAPRE3 interactions	MAP1A TTC28 GAS2L3 MAP4 APC2 CAMSAP3 NCKAP5L SPECC1 C6orf132 TTBK2 LARP4B DST MACF1 CEP131 PRRC2A DCLK1 CEP170B	2.52e-12	230	155	17	int:MAPRE3
Interaction	TOP3B interactions	MPP3 CRYBG2 ANKS6 KMT2B MYCBP2 KIF26A SPEG AKNA C15orf39 CUL9 FHIP1B KIFC2 ARHGEF10L C6orf132 FBXL6 MICALL1 PKMYT1 SCAF1 NCOR2 LARP4B KMT2D DST ARAP3 TULP4 ATXN2 RALGPS1 BRD4 SAC3D1 MLLT6 CEP131 WDR90 GNAS SNAPC4 MBD5 SPEN PRRC2A CEP170B SOWAHB AGAP3	4.69e-12	1470	155	39	int:TOP3B
Interaction	DCTN1 interactions	MAP1A GAS2L3 PRR36 MYCBP2 MAP4 NACA CAMSAP3 NCKAP5L SPECC1 ZNF512B MSH6 DST PPP4R2 CEP41 MACF1 CEP131 DCLK1 CEP170B AGAP3	9.70e-09	497	155	19	int:DCTN1
Interaction	YWHAB interactions	CARMIL2 TTC28 RASGRF1 MYCBP2 ARHGEF5 SPEG CAMSAP3 PARD3B NCKAP5L SPECC1 RGS12 C6orf132 MICALL1 USP31 TBC1D10B DST RALGPS1 RBMX MACF1 CEP131 DCLK1 CEP170B EPB41L1 AGAP1 AGAP2 AGAP3	6.05e-08	1014	155	26	int:YWHAB
Interaction	YWHAE interactions	CARMIL2 TTC28 RASGRF1 MYCBP2 ARHGEF5 CAMSAP3 PARD3B ZC3H18 HMGA1 NCKAP5L SPECC1 RGS12 C6orf132 MICALL1 USP31 NCOR2 MIDN DST BRD4 MACF1 CEP131 MGA PRRC2A DCLK1 CEP170B EPB41L1 AGAP1 AGAP3	3.19e-07	1256	155	28	int:YWHAE
Interaction	TRIM36 interactions	MAP1A GAS2L3 MAP4 CAMSAP3 SPECC1 ZNF512B USP31 DCLK1 CEP170B	1.75e-06	144	155	9	int:TRIM36
Interaction	YWHAZ interactions	CARMIL2 TTC28 RASGRF1 RASGRF2 MYCBP2 WDR7 ARHGEF5 SPEG CAMSAP3 PARD3B ZC3H18 NCKAP5L SPECC1 RGS12 C6orf132 MICALL1 USP31 DST NFATC4 BRD4 MACF1 CEP131 PRRC2A DCLK1 CEP170B EPB41L1 AGAP1	2.74e-06	1319	155	27	int:YWHAZ
Interaction	YWHAH interactions	CARMIL2 TTC28 MYCBP2 ARHGEF5 SPEG CAMSAP3 PARD3B KIAA1191 NCKAP5L SPECC1 RGS12 C6orf132 MICALL1 USP31 TBC1D10B DST BRD4 MACF1 CEP131 DCLK1 CEP170B EPB41L1 AGAP1 AGAP3	3.74e-06	1102	155	24	int:YWHAH
Interaction	SYNGAP1 interactions	AMPH MAP1A MYCBP2 MAP4 WDR7 SH3KBP1 FCHO2 GNAS EPB41L1 AGAP1 AGAP2 AGAP3	4.70e-06	307	155	12	int:SYNGAP1
Interaction	SFN interactions	ITCH MAP1A MYCBP2 MAP4 ARHGEF5 CAMSAP3 PARD3B ZC3H18 NCKAP5L SPECC1 RGS12 C6orf132 USP31 DST RBMX MACF1 CEP131 CEP170B	6.52e-06	692	155	18	int:SFN
Interaction	RCOR1 interactions	KMT2B TTC28 MYCBP2 CAMSAP3 C15orf39 HMGA1 NCKAP5L MSH6 NCOR2 KMT2D DST BRD4 CEP131 MGA SPEN	6.59e-06	494	155	15	int:RCOR1
Interaction	SLC6A4 interactions	DUSP2 APC2 CAMSAP3 FCHO2 HCN2 CCDC177 SPECC1 TBC1D10B MACF1 CEP170B EPB41L1 AGAP1 AGAP2 AGAP3	7.42e-06	437	155	14	int:SLC6A4
Interaction	SSPOP interactions	TTC28 ATXN7L1 RNF123	1.53e-05	7	155	3	int:SSPOP
Interaction	YWHAQ interactions	ITCH CARMIL2 TTC28 MYCBP2 MAP4 ARHGEF5 SPEG CAMSAP3 PARD3B NCKAP5L SPECC1 RGS12 C6orf132 USP31 DST NFATC4 BRD4 MACF1 CEP131 DCLK1 CEP170B EPB41L1 AGAP1	1.53e-05	1118	155	23	int:YWHAQ
Interaction	YWHAG interactions	ITCH CARMIL2 TTC28 MYCBP2 ARHGEF5 SPEG CAMSAP3 PARD3B NCKAP5L SPECC1 RGS12 C6orf132 MICALL1 USP31 TBC1D10B DST MACF1 CEP131 GNAS DCLK1 CEP170B EPB41L1 AGAP1 AGAP3	2.95e-05	1248	155	24	int:YWHAG
Interaction	MAPRE1 interactions	APC2 CAMSAP3 KIAA1191 NCKAP5L SPECC1 TTBK2 DST BRD4 MACF1 CEP131 WDR90 PRRC2A GOLGA1 CEP170B	4.47e-05	514	155	14	int:MAPRE1
Interaction	DPYSL2 interactions	ITCH MAP1A MAP4 NACA CAVIN3 FAM186B MICALL1 LARP4B RNF123 BRD4 AGAP2	4.71e-05	327	155	11	int:DPYSL2
Interaction	RAC1 interactions	ITCH CARMIL2 RASGRF1 RASGRF2 DUSP2 GMIP FCHO2 NCKAP5L SPECC1 MICALL1 ARHGAP4 TBC1D10B BMPR2 MIDN DST RBMX MACF1 GNAS EPB41L1 AGAP1 AGAP2	6.69e-05	1063	155	21	int:RAC1
Interaction	CEBPA interactions	ITCH CEBPD KMT2B RASGRF1 MYCBP2 MAP4 C15orf39 HMGA1 TGIF1 MSH6 NCOR2 KMT2D ATXN2 NFATC4 PPP4R2 RBMX BRD4 SUGP1 MACF1 MLLT6 SPEN CDCA5 PRRC2A	8.12e-05	1245	155	23	int:CEBPA
Interaction	SRPK2 interactions	MPP3 RASGRF1 TCOF1 MYCBP2 MAP4 TOGARAM1 ZC3H18 HMGA1 FBXL6 SCAF1 DCAF10 RBMX MACF1 SPEN PRRC2A EPB41L1	1.34e-04	717	155	16	int:SRPK2
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	MEF2B PEX11G PRR36 C19orf67 APC2 CAMSAP3 GMIP HCN2 MIDN BRD4 SUGP1 KCNN1 LYL1	5.00e-06	797	160	13	chr19p13
Cytoband	12q13.12	NCKAP5L FAM186B KMT2D	3.20e-04	38	160	3	12q13.12
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 RASGRF2 SH2B1 ARAP3 RALGPS1 AGAP1 AGAP2 AGAP3	2.33e-05	206	103	8	682
GeneFamily	ArfGAPs	ARAP3 AGAP1 AGAP2 AGAP3	3.58e-05	33	103	4	395
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF1 RASGRF2 ARHGEF5 ARHGEF15 ARHGEF10L	3.69e-05	66	103	5	722
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP1 AGAP2 AGAP3	1.15e-04	17	103	3	1291
GeneFamily	LIM domain containing	ZNF185 CRIP3 MICALL1 LDB3	3.55e-04	59	103	4	1218
GeneFamily	Ataxins\|Trinucleotide repeat containing	NCOR2 KMT2D ATXN2	3.77e-04	25	103	3	775
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	8.80e-04	8	103	2	939
GeneFamily	Fibronectin type III domain containing	BOC TSPOAP1 VWA1 FNDC1 FSD1L	2.22e-03	160	103	5	555
GeneFamily	Ankyrin repeat domain containing	ANKS6 ARAP3 SOWAHB AGAP1 AGAP2 AGAP3	2.62e-03	242	103	6	403
GeneFamily	T-boxes	TBX18 MGA	4.63e-03	18	103	2	766
Coexpression	LIAO_METASTASIS	GAS2L3 MAP4 NACA HMGA1 KIFC2 SH2B1 MICALL1 ARHGAP4 PLXNC1 ALPK3 HES4 SAC3D1 GNAS SNAPC4 PRRC2A	1.22e-06	540	160	15	M13809
CoexpressionAtlas	gudmap_RNAseq_e15.5_Podocytes_2500_K0	AMPH ANKS6 CEBPD KIF26A SPEG DUSP2 WIPF3 C15orf39 CAVIN3 SEMA3G NCKAP5L ADAM8 EMILIN1 ARHGEF15 FBXL6 MICALL1 TBX18 SCAF1 MIDN ARAP3 SORCS2 GNAS FAM181B LYL1	3.23e-06	1143	156	24	gudmap_RNAseq_e15.5_Podocytes_2500_K0
CoexpressionAtlas	mendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K3	AMPH PRR36 ARHGEF5 ZNF185 CAMSAP3 WIPF3 C15orf39 HMGA1 ARHGEF10L C6orf132 PKMYT1 USP31 TGIF1 MIDN BCL11B RALGPS1 SORCS2 CCDC120 MLLT6 JPT1 IRX2 CEP170B EPB41L1	5.26e-05	1266	156	23	mendel_RNAseq_e12.5_Urothelium_ShhCreRFP_2500_K3
CoexpressionAtlas	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0	MPP3 AEN AMPH TSPOAP1 SPEG PAXX WIPF3 HMGA1 NCKAP5L ADAM8 SH2B1 ARHGEF10L PKMYT1 TGIF1 SCAF1 MIDN BCL11B RALGPS1 CCDC120 SAC3D1 MLLT6 PRRC2A CEP170B	5.86e-05	1275	156	23	gudmap_RNAseq_e11.5_Ureteric_stalks_2500_K0
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 AKNA SCML4 RNF123 BCL11B AEBP2 TAF4B AGAP2	2.20e-07	174	159	8	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 AKNA SCML4 RNF123 BCL11B AEBP2 TAF4B AGAP2	2.20e-07	174	159	8	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 KIF26A PARD3B EMILIN1 ARHGEF15 BMPR2 ARAP3 PLXNC1	4.83e-07	193	159	8	d485634c564b268e344b6a2863c26f6adaec9e38
ToppCell	COVID-19_Severe-cDC\|COVID-19_Severe / disease group, cell group and cell class	CEBPD DUSP2 ADAM8 CRIP3 MIDN DST FCGRT CST3	5.22e-07	195	159	8	6419090b19de7b5d5140eaecf231860273da2c0d
ToppCell	COVID-19_Moderate-cDC\|World / disease group, cell group and cell class	CEBPD GAS2L3 ADAM8 SPECC1 CRIP3 DST FCGRT CST3	5.43e-07	196	159	8	92a236adf386f05d020b1954bbdc5bd32346cbf0
ToppCell	Healthy-cDC\|Healthy / disease group, cell group and cell class	CEBPD HMGA1 ADAM8 SPECC1 CRIP3 DST FCGRT CST3	5.86e-07	198	159	8	4cf874333b9fd6cd22ee647cd12c032fc6d05740
ToppCell	control-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CEBPD C15orf39 ARHGEF10L MIDN DST FCGRT PLXNC1 CST3	5.86e-07	198	159	8	35499a5231818e3432cf69b5c4a58c02f7771db8
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEBPD GAS2L3 ZDHHC1 MIDN FCGRT CST3 HES4 JPT1	5.86e-07	198	159	8	e2038d9239e23d670d539f1c58475fd0de028e51
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KMT2B MAP1A NCKAP5L TTBK2 BCL11B CEP170B VWA5B1	2.02e-06	163	159	7	953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCell	normal_Lung-Myeloid_cells-CD163+CD14+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	CEBPD TCOF1 DUSP2 SH3KBP1 ADAM8 CST3 VWA5B1	2.28e-06	166	159	7	07b498eb341abec02a3ccaae320bdbb5cd6883c5
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.36e-06	176	159	7	9d4a4dfeebb5a8a0f3ab18c37c8ddc2cd2158575
ToppCell	LPS-IL1RA+antiTNF-Lymphocytic_NKT-T_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.36e-06	176	159	7	bb41e9478373726eb460af764de0277b2d09928e
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-T-cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.36e-06	176	159	7	bfbab3c5b738b3b0b1540f2059d0245fbd8c0031
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.36e-06	176	159	7	ea27e18407b8a13e8212830da859efeb8f158690
ToppCell	droplet-Liver-LIVER_HEP-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 MYCBP2 MAP4 PARD3B BMPR2 PLXNC1 MACF1	3.90e-06	180	159	7	dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCell	LPS_only-Lymphocytic_NKT-T_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.90e-06	180	159	7	dcef253f2e97e4436b1b04e8a06a53ff6e64522c
ToppCell	droplet-Liver-LIVER_HEP\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 MYCBP2 MAP4 PARD3B BMPR2 PLXNC1 MACF1	3.90e-06	180	159	7	423454e3390080ae03bb3cbb267255ebfe4df080
ToppCell	LPS_only-Lymphocytic_NKT-T_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CARMIL2 DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	4.05e-06	181	159	7	a4347ae554e6dcf03c7001a2b69332b377c7c034
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 PARD3B EMILIN1 ARHGEF15 ARAP3 PLXNC1 INPP5J	4.35e-06	183	159	7	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 PARD3B EMILIN1 ARHGEF15 ARAP3 PLXNC1 INPP5J	4.35e-06	183	159	7	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A GAS2L3 APC2 VWA1 FNDC1 SORCS2 FAM181B	4.67e-06	185	159	7	ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRAG1 NCKAP5L EMILIN1 TBX18 NFATC4 WDR90 SNAPC4	4.67e-06	185	159	7	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IRAG1 NCKAP5L EMILIN1 TBX18 NFATC4 WDR90 SNAPC4	4.67e-06	185	159	7	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEBPD GAS2L3 C15orf39 HMGA1 ARHGEF10L FCGRT CST3	5.01e-06	187	159	7	5917bdfe84cf5941e21b415aebbab3090cc5d576
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1A RASGRF2 KIF26A SEMA3G ARHGEF15 FNDC1 FAM181B	5.01e-06	187	159	7	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	10x5'v1-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	AMPH VWA1 DST IRX2 DCLK1 EPB41L1 AGAP1	5.38e-06	189	159	7	473b01c9162b12b90a617c600238436177a0d18d
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TCOF1 HMGA1 SPECC1 CRIP3 DST FCGRT CST3	5.57e-06	190	159	7	4b25d49f033bbd326b47cf5602af3f0262cfc367
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MPP3 CARMIL2 RASGRF1 MYCBP2 TSPOAP1 CAMSAP3 KIFC2	5.57e-06	190	159	7	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-conventional_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TCOF1 HMGA1 SPECC1 CRIP3 DST FCGRT CST3	5.96e-06	192	159	7	8e606eae3e5b07a856d3c2a74186d486da96309c
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 PARD3B EMILIN1 ARHGEF15 BMPR2 ARAP3 PLXNC1	6.17e-06	193	159	7	826b8dd801298b3e0cd76232feae5a14026b8806
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC28 PARD3B EMILIN1 ARHGEF15 BMPR2 ARAP3 PLXNC1	6.17e-06	193	159	7	87d3a577d37fb0cb4b6313c596310de452bc3872
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AMPH CEBPD FCHO2 ARHGAP4 MIDN FCGRT CST3	6.17e-06	193	159	7	1db487e5f81849740d57cc3e2b5739e8f7581efb
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	AMPH CEBPD FCHO2 ARHGAP4 MIDN FCGRT CST3	6.38e-06	194	159	7	a94f9f7179a5733e3c378ff8b337e288785433a1
ToppCell	Bronchial_Brush-Immune-Dendritic_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	CEBPD DUSP2 ADAM8 SPECC1 PLXNC1 CST3 HES4	6.38e-06	194	159	7	dbcc00940538efc0f89f074dbe822c50efa5ad8e
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MPP3 ADAM8 SPECC1 CRIP3 DST FCGRT CST3	6.60e-06	195	159	7	dd28c63b53f2a97e3fac127294a465870dc371b3
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	6.60e-06	195	159	7	0fcc41cda3e5f921748cf7e7fe48dd7ca1de4636
ToppCell	PBMC-Severe-Myeloid-cDC-cDC-cDC_9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MPP3 ADAM8 SPECC1 CRIP3 DST FCGRT CST3	6.60e-06	195	159	7	d6ff38535898f90be6719cd5152291f2f4f8a746
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	6.82e-06	196	159	7	e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEBPD C15orf39 ZDHHC1 FCGRT PLXNC1 CST3 HES4	6.82e-06	196	159	7	51fc8bb9a806f8fbf78d5d80d535f1068a9770c2
ToppCell	PBMC-Control-Myeloid-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	6.82e-06	196	159	7	d376168e15ec1cf618723259966c76be3698b9b0
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	6.82e-06	196	159	7	4e1f8828413896ab8a4ec92a89d6789e8e37e05a
ToppCell	Control-Myeloid-cDC\|Control / Disease group, lineage and cell class	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	6.82e-06	196	159	7	85d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	6.82e-06	196	159	7	553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	6.82e-06	196	159	7	0f3c7fd450aaa1f866b8558692534c0ea2a34e75
ToppCell	PBMC-Control-Myeloid-cDC-cDC\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	6.82e-06	196	159	7	4a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG COL27A1 IRAG1 SPECC1 TBX18 LDB3 FAM181B	7.05e-06	197	159	7	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	7.05e-06	197	159	7	f73ece3aca28c0db5db0f12e026d42c6c36b9efb
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	7.05e-06	197	159	7	e70e7d97823a762def3970d94a0e897981a6c922
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	C15orf39 ZDHHC1 FCGRT PLXNC1 CST3 HES4 LYL1	7.05e-06	197	159	7	989eaf7ecef8683e3ec6ec024fd193a2f5861b26
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	7.05e-06	197	159	7	2b3a56bb1d40bc1284a5931c4e7b373660de5402
ToppCell	COVID-19_Severe-Lymphoid_T/NK-CD8+_Tem\|COVID-19_Severe / Disease group, lineage and cell class	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	7.05e-06	197	159	7	f0bac4d5c3160933ac3786cec8dadffb35d711ea
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RASGRF1 VWA1 HCN2 USP31 LDB3 DST AGAP1	7.05e-06	197	159	7	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	PBMC-Severe-Lymphocyte-T/NK-CD8+_T-CD8+_Tem-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DUSP2 PAXX AKNA BCL11B MACF1 MLLT6 AGAP1	7.05e-06	197	159	7	bce0135a96910d2bace62a3408a1a6fdac0cf0df
ToppCell	normal_Lymph_Node-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	CEBPD TCOF1 DUSP2 AKNA ADAM8 MIDN CST3	7.05e-06	197	159	7	2b3cd318c988364adcba4441444045914d58fe46
ToppCell	COVID-19_Moderate-cDC\|COVID-19_Moderate / disease group, cell group and cell class	CEBPD ADAM8 SPECC1 CRIP3 DST FCGRT CST3	7.05e-06	197	159	7	ff45a212434a1b128e1a217c6abdec6380938da9
ToppCell	normal_Lung-Myeloid_cells-CD1c+_DCs\|Myeloid_cells / Location, Cell class and cell subclass	CEBPD TCOF1 DUSP2 SH3KBP1 HMGA1 ADAM8 CST3	7.05e-06	197	159	7	d051617f7cf96485715c343cff72833c2124512d
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 FNDC1 LDB3	7.29e-06	198	159	7	e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCell	PBMC\|World / Compartment, Disease Groups and Clusters	CEBPD TCOF1 DUSP2 SH3KBP1 SPECC1 MIDN GNAS	7.29e-06	198	159	7	84f5b43dad0c57556171dbc0b799735654582ecf
ToppCell	remission-Non-classical_Monocyte\|World / disease stage, cell group and cell class	IRAG1 ZDHHC1 FCGRT PLXNC1 CST3 HES4 LYL1	7.29e-06	198	159	7	1c170655070acca00520b7cf9c510a04c0a90a8f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CAVIN3 HMGA1 SPECC1 CRIP3 DST FCGRT CST3	7.29e-06	198	159	7	d0371e2ca9e25727b35985940f6228f9d8e49727
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	7.29e-06	198	159	7	b0e090000d1cdee4628f4ab252f6b444658f80f5
ToppCell	systemic_lupus_erythematosus-managed-Myeloid-conventional_dendritic_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	7.29e-06	198	159	7	99f98e240d81cfe5b485da2598f8392d7cbd9013
ToppCell	COVID-19_Severe-cDC\|World / disease group, cell group and cell class	CEBPD HMGA1 SPECC1 CRIP3 DST FCGRT CST3	7.29e-06	198	159	7	c452334249f047265ae89dcabe7de446d968cae6
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	CEBPD C15orf39 ZDHHC1 FCGRT PLXNC1 CST3 HES4	7.53e-06	199	159	7	fa5ad81554969fffe5e779614d071d9194a7182c
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 FCHO2 ARHGEF15 BMPR2 DST ARAP3 MACF1	7.78e-06	200	159	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	distal-mesenchymal-Airway_Smooth_Muscle-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 LDB3 HES4	7.78e-06	200	159	7	f09eaa52e11262ec47f3dcb4d890e240eaaa2b3d
ToppCell	COVID-19-COVID-19_Mild-Myeloid-cDC\|COVID-19_Mild / Disease, condition lineage and cell class	CEBPD ADAM8 SPECC1 CRIP3 DST FCGRT CST3	7.78e-06	200	159	7	b8f52e65813d331c49cdd5f354fdfec6fc8c339e
ToppCell	COVID-19-COVID-19_Convalescent-Myeloid-CD16+_Monocyte\|COVID-19_Convalescent / Disease, condition lineage and cell class	IRAG1 ZDHHC1 FCGRT PLXNC1 CST3 HES4 LYL1	7.78e-06	200	159	7	f24abb2d54d6423ee886285e3c66a874ec59e1a3
ToppCell	medial-2-mesenchymal-Airway_Smooth_Muscle\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 LDB3 HES4	7.78e-06	200	159	7	16b00eacbea4d75cf814803d3fc0b82c2b8c0a9c
ToppCell	COVID\|World / Condition, Cell_class and T cell subcluster	CEBPD FCHO2 ARHGEF10L FCGRT CST3 GNAS LYL1	7.78e-06	200	159	7	04a932fe2431e7886120c219ce666f90d3030a1c
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MAP4 FCHO2 ARHGEF15 BMPR2 DST ARAP3 MACF1	7.78e-06	200	159	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	COVID-19-COVID-19_Severe-Myeloid-cDC\|COVID-19_Severe / Disease, condition lineage and cell class	CEBPD ADAM8 SPECC1 CRIP3 DST FCGRT CST3	7.78e-06	200	159	7	e7b808d8ed65343a4345fafb03015fe4f7ce302f
ToppCell	Sepsis-ICU-NoSEP-Myeloid-cDC2\|ICU-NoSEP / Disease, condition lineage and cell class	RASGRF1 DUSP2 HMGA1 ADAM8 DST CST3 TAF4B	7.78e-06	200	159	7	59cb0b0dee2599b3d3014b66d71d84c22b5de4b2
ToppCell	distal-mesenchymal-Airway_Smooth_Muscle-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 LDB3 HES4	7.78e-06	200	159	7	bc969a956f62570419a5faaf0ab0fd17b343c5ca
ToppCell	medial-mesenchymal-Airway_Smooth_Muscle\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 LDB3 HES4	7.78e-06	200	159	7	c1d9748aaae489d26e24602a5dcbe7f5fa9a5548
ToppCell	medial-mesenchymal-Airway_Smooth_Muscle-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 LDB3 HES4	7.78e-06	200	159	7	6a5047018b12be3bc4b55a64d42e52e96c624003
ToppCell	distal-mesenchymal-Airway_Smooth_Muscle\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SPEG CAVIN3 ADAMTS8 IRAG1 EMILIN1 LDB3 HES4	7.78e-06	200	159	7	1b5ac5b3ddd4df32e940531cc020998f8cd95c2c
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ANKS6 SPECC1 ZNF512B PLXNC1 RALGPS1 MLLT6	1.60e-05	149	159	6	a85a051e0d82430160967e72fa04b55f43e84513
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_4\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ANKS6 SPECC1 ZNF512B PLXNC1 RALGPS1 MLLT6	1.67e-05	150	159	6	7a381f5ae94eba5eb60dcbf83416b4eb18c279ea
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRDM10-DT GMIP KMT2D PPP4R2 AEBP2 AGAP2	1.80e-05	152	159	6	0652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCell	facs-Skin-nan-24m-Epithelial-inner_bulge\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPP3 SH3KBP1 FAM186B SLITRK2 CST3 SOWAHB	2.01e-05	155	159	6	fa2776d258e0420b2895de1008e292ad7725dac0
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPD KIF26A VWA1 ARHGEF15 ARAP3 FCGRT	2.23e-05	158	159	6	a2efcc184ef13d81373e3690253ba35f6be09c5f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPD KIF26A VWA1 ARHGEF15 ARAP3 FCGRT	2.23e-05	158	159	6	e52eff2bd1e7e0ce9c278ed5109802865e0fe69c
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEBPD KIF26A VWA1 ARHGEF15 ARAP3 FCGRT	2.23e-05	158	159	6	ba9998cbf786c515d30fe42de02c7a246db1b6f9
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DUSP2 ADAMTS8 EMILIN1 HES4 GNAS DCLK1	2.57e-05	162	159	6	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DUSP2 ADAMTS8 EMILIN1 HES4 GNAS DCLK1	2.57e-05	162	159	6	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	MAP4 ARHGEF10L MTF1 LYL1 MGA SPEN	2.57e-05	162	159	6	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DUSP2 ADAMTS8 EMILIN1 HES4 GNAS DCLK1	2.57e-05	162	159	6	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	DUSP2 ADAMTS8 IRAG1 ADAM8 FNDC1 BRWD1-AS2	2.66e-05	163	159	6	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C19orf67 DUSP2 AKNA ADAM8 SCML4 BCL11B	2.95e-05	166	159	6	9fae71b0a42a9b2222453c03e0a1e83f30117ae9
ToppCell	COVID-CD8-exh_CD4\|COVID / Condition, Cell_class and T cell subcluster	ARHGEF5 ZNF185 KIAA1191 NFS1 LARP4B DCAF10	2.95e-05	166	159	6	4ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell	CV-Mild-3\|Mild / Virus stimulation, Condition and Cluster	CABLES2 TCOF1 PKMYT1 AJM1 WDR90 SNAPC4	2.95e-05	166	159	6	5599f90fc0e15a3670b03187085eba91228390a2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RASGRF2 CAVIN3 SEMA3G SPECC1 ARHGEF15 ARAP3	2.95e-05	166	159	6	8e5f2afbeffae5e77fcb29e8fe9f5aa49779b619
ToppCell	Adult-Endothelial-endothelial_cell_of_artery-D122\|Adult / Lineage, Cell type, age group and donor	RASGRF2 KIF26A SPEG SEMA3G ARHGEF15 ARAP3	3.15e-05	168	159	6	8c3e1e45b422813bcdfa4273b1167db649a312f5
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6\|TCGA-Liver / Sample_Type by Project: Shred V9	BOC MAP1A KIF26A IRAG1 LDB3 DCLK1	3.26e-05	169	159	6	e992530776cab922d0360b275fb9cb8bd0017b06
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells-T-cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.48e-05	171	159	6	539ea88acc6f948efdeae8b69e5c5ffaee29f1d9
ToppCell	LPS-IL1RA-Lymphocytic_NKT-T_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DUSP2 HMGA1 SCML4 TBC1D10B BCL11B TAF4B	3.60e-05	172	159	6	0fc692be845d4225ff8b63bf9195724fc8510c2c
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 SH3KBP1 SCML4 PKMYT1 ARHGAP4 BCL11B	3.84e-05	174	159	6	fedadde222df1952d6456f4f3413c01579146e1f
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	TTC28 GAS2L3 ARHGEF10L DST FCGRT CST3	3.84e-05	174	159	6	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	facs-Lung-EPCAM-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DUSP2 SH3KBP1 SCML4 PKMYT1 ARHGAP4 BCL11B	3.84e-05	174	159	6	e69a011ae9698368923223d3af3243e609c08c83
Drug	Cyclobenzaprine hydrochloride [6202-23-9]; Up 200; 12.8uM; HL60; HT_HG-U133A	AEN TCOF1 MYCBP2 MAP4 ADAM8 LARP4B ARAP3 SUGP1 SNAPC4 LYL1	1.03e-06	192	159	10	1332_UP
Drug	Riboflavine [83-88-5]; Up 200; 10.6uM; HL60; HG-U133A	RGS12 ARHGEF15 ARHGAP4 MTF1 FCGRT SUGP1 SAC3D1 SNAPC4 PRRC2A	1.05e-05	197	159	9	1767_UP
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	TTC28 MAP4 C15orf39 SH2B1 FBXL6 MICALL1 PLXNC1 GPR153 SUGP1	1.10e-05	198	159	9	4805_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MAP1A C15orf39 GMIP GPR153 BRD4 KCNN1 TAF4B PRRC2A INPP5J	1.10e-05	198	159	9	7035_UP
Drug	bromfenacoum	MAP4 NACA CAMSAP3 ZC3H18 HMGA1 KIAA1191 SPECC1 SCAF1 DST ATXN2 SORCS2 MACF1 CEP170B INPP5J EPB41L1	4.79e-05	644	159	15	ctd:C013418
Drug	tertiary carboxamide	BOC DST	4.85e-05	2	159	2	CID006419719
Drug	tetrabromobisphenol A	BOC CEBPD COL27A1 DUSP2 AKNA CAVIN3 HMGA1 EMILIN1 KIFC2 SCML4 LDB3 SLITRK2 ARAP3 NFATC4 FCGRT GPR153 AEBP2 SORCS2	5.30e-05	891	159	18	ctd:C020806
Drug	chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A	CEBPD C15orf39 GMIP ARHGEF10L FBXL6 FCGRT SUGP1 PRRC2A	6.80e-05	194	159	8	1217_DN
Drug	Tiabendazole [148-79-8]; Down 200; 19.8uM; MCF7; HT_HG-U133A	KMT2B TTC28 MAP4 DUSP2 MICALL1 TGIF1 LARP4B BCL11B	6.80e-05	194	159	8	2840_DN
Drug	Nialamide [51-12-7]; Down 200; 13.4uM; MCF7; HT_HG-U133A	MPP3 CRYBG2 KMT2B TTC28 PRR36 ADAM8 RGS12 NCOR2	7.05e-05	195	159	8	3871_DN
Drug	Oxethazaine [126-27-2]; Up 200; 8.6uM; PC3; HG-U133A	NACA GMIP ADAM8 MICALL1 RNF123 MTF1 CST3 PRRC2A	7.05e-05	195	159	8	1903_UP
Drug	Clofazimine [2030-63-9]; Down 200; 8.4uM; MCF7; HT_HG-U133A	MPP3 PRR36 CUL9 RGS12 ARHGEF10L FBXL6 GPR153 SUGP1	7.05e-05	195	159	8	5277_DN
Drug	Sulfisoxazole [127-69-5]; Up 200; 15uM; MCF7; HT_HG-U133A	MAP1A SEMA3G ADAM8 RGS12 LDB3 GPR153 CEP41 KCNN1	7.31e-05	196	159	8	5622_UP
Drug	Methiazole; Down 200; 15uM; MCF7; HT_HG-U133A	CRYBG2 ADAM8 MICALL1 ARHGAP4 NCOR2 PLXNC1 SUGP1 LYL1	7.31e-05	196	159	8	3878_DN
Drug	Budesonide [51333-22-3]; Down 200; 9.2uM; HL60; HG-U133A	MAP4 TOGARAM1 ARHGEF15 TTBK2 TULP4 MTF1 SNAPC4 PRRC2A	7.31e-05	196	159	8	1716_DN
Drug	Pyrazinamide [ 98-96-4]; Up 200; 32.4uM; MCF7; HT_HG-U133A	MPP3 AEN ATXN7L1 CUL9 RGS12 SUGP1 GNAS LYL1	7.58e-05	197	159	8	2839_UP
Drug	Fosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A	PRR36 CUL9 ADAM8 RGS12 FBXL6 SUGP1 GOLGA1 INPP5J	7.58e-05	197	159	8	4823_DN
Drug	Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A	MAP4 CUL9 ADAM8 LARP4B RNF123 SUGP1 PRRC2A AGAP2	7.58e-05	197	159	8	2641_DN
Drug	Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	TCOF1 ATXN7L1 SPEG ADAM8 MSH6 NCOR2 RALGPS1 SUGP1	7.58e-05	197	159	8	6758_DN
Drug	Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; PC3; HT_HG-U133A	MAP4 C15orf39 FBXL6 BCL11B FCGRT BRD4 SUGP1 EPB41L1	7.58e-05	197	159	8	6360_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	TTC28 PRR36 MAP4 SH2B1 TTBK2 MTF1 PLXNC1 CEP170B	7.85e-05	198	159	8	4800_DN
Drug	Chlorzoxazone [95-25-0]; Down 200; 23.6uM; PC3; HT_HG-U133A	KMT2B MAP4 SPEG ADAM8 SH2B1 MICALL1 ZNF512B SNAPC4	7.85e-05	198	159	8	2100_DN
Drug	Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; PC3; HT_HG-U133A	MPP3 ITCH MAP4 ADAM8 SH2B1 MTF1 CEP131 GNAS	7.85e-05	198	159	8	2097_DN
Drug	Levodopa [59-92-7]; Up 200; 20.2uM; PC3; HG-U133A	MAP4 SEMA3G ARHGEF15 ATXN2 MTF1 TAF4B SNAPC4 EPB41L1	8.13e-05	199	159	8	1892_UP
Drug	Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	GMIP ADAM8 RNF123 RALGPS1 CEP131 SNAPC4 PRRC2A CEP170B	8.13e-05	199	159	8	3430_DN
Drug	LY 294002; Down 200; 10uM; PC3; HT_HG-U133A	AEN TCOF1 SPEG C15orf39 ZNF512B MTF1 SUGP1 EPB41L1	8.13e-05	199	159	8	1227_DN
Disease	cystatin C measurement, chronic kidney disease	ATXN2 CST3	2.67e-05	2	153	2	EFO_0003884, EFO_0004617
Disease	complex cortical dysplasia with other brain malformations (is_implicated_in)	KIF26A APC2	1.59e-04	4	153	2	DOID:0090131 (is_implicated_in)
Disease	cortical surface area measurement	ITCH MYCBP2 DUT CUL9 PARD3B FCHO2 IRAG1 PKMYT1 BCL11B ATXN2 RALGPS1 FOXL2NB HES4 MACF1 PRRC2A DCLK1 AGAP1 AGAP3	2.21e-04	1345	153	18	EFO_0010736
Disease	calcium measurement	MAP1A ATXN7L1 SEMA3G FCHO2 IRAG1 RGS12 BCL11B FCGRT AEBP2 MACF1 GNAS	4.55e-04	628	153	11	EFO_0004838
Disease	fatty acid measurement	MPP3 AMPH MEF2B SPCS1 GMIP RGS12 FCGRT SUGP1 MACF1	4.74e-04	436	153	9	EFO_0005110
Disease	Polycystic kidney disease, type 2	ANKS6 BRD4	5.51e-04	7	153	2	C2751306
Disease	vitamin k-dependent protein S measurement	COL27A1 AKNA	5.51e-04	7	153	2	EFO_0020850
Disease	total blood protein measurement	CABLES2 MEF2B SH3KBP1 RGS12 NCOR2 KMT2D ATXN2 FCGRT MACF1	5.85e-04	449	153	9	EFO_0004536
Disease	facial hair thickness measurement	FOXL2NB MACF1 AGAP3	6.07e-04	32	153	3	EFO_0007823
Disease	cortical thickness	KMT2B MYCBP2 CUL9 ADAMTS8 IRAG1 SPECC1 MICALL1 BCL11B ATXN2 PLXNC1 RALGPS1 FOXL2NB MACF1 AGAP1 AGAP3	7.02e-04	1113	153	15	EFO_0004840
Disease	Polycystic Kidney, Type 1 Autosomal Dominant Disease	ANKS6 BRD4	7.33e-04	8	153	2	C0887850
Disease	diastolic blood pressure, systolic blood pressure	SPEG DUT ADAMTS8 RGS12 ZNF512B TBX18 MSH6 BCL11B ATXN2 PLXNC1 BRD4	7.76e-04	670	153	11	EFO_0006335, EFO_0006336
Disease	Polycystic Kidney, Autosomal Dominant	ANKS6 BRD4	9.39e-04	9	153	2	C0085413
Disease	multiple sclerosis	MEF2B TTC28 RASGRF1 TSPOAP1 ZNF767P USP31 NCOR2 ATXN2 PLXNC1 AGAP2	1.11e-03	594	153	10	MONDO_0005301
Disease	tauopathy (implicated_via_orthology)	MAP4 SH3KBP1	1.17e-03	10	153	2	DOID:680 (implicated_via_orthology)
Disease	level of Ceramide (d42:1) in blood serum	MEF2B SUGP1	1.17e-03	10	153	2	OBA_2045187
Disease	coagulation factor XA measurement	COL27A1 AKNA	1.42e-03	11	153	2	EFO_0020266
Disease	coagulation factor X measurement	COL27A1 AKNA	2.01e-03	13	153	2	EFO_0020265
Disease	dystonia (is_implicated_in)	KMT2B TSPOAP1	2.33e-03	14	153	2	DOID:543 (is_implicated_in)
Disease	serum non-albumin protein measurement	CARMIL2 FCHO2 NCOR2 MIDN ATXN2 FCGRT PRRC2A	2.86e-03	361	153	7	EFO_0004568
Disease	Cardiovascular Abnormalities	ANKS6 APC2	3.06e-03	16	153	2	C0243050
Disease	T-Cell Lymphoma	KMT2D MGA	3.06e-03	16	153	2	C0079772
Disease	atrial fibrillation	ZNF689 NACA HMGA1 NCOR2 HES4 MBD5 SPEN	3.32e-03	371	153	7	EFO_0000275
Disease	birth weight, parental genotype effect measurement	COL27A1 HMGA1 ZNF512B ARAP3 ATXN2	3.33e-03	192	153	5	EFO_0004344, EFO_0005939
Disease	copine-1 measurement	NFS1 EPB41L1	3.45e-03	17	153	2	EFO_0008102
Disease	alcoholic liver cirrhosis	SUGP1 TAF4B	3.45e-03	17	153	2	EFO_1000802
Disease	Colorectal Carcinoma	BOC RASGRF2 TCOF1 APC2 ARHGEF10L MSH6 BCL11B ARAP3 GNAS DCLK1	3.73e-03	702	153	10	C0009402
Disease	serum albumin measurement	MAP1A MAP4 SH3KBP1 FCHO2 RGS12 SCAF1 ATXN2 FCGRT MACF1	3.85e-03	592	153	9	EFO_0004535
Disease	loneliness measurement	DCAF10 MACF1 MBD5 AGAP3	4.03e-03	124	153	4	EFO_0007865
Disease	factor VIII measurement, Ischemic stroke	FCHO2 ATXN2	4.31e-03	19	153	2	EFO_0004630, HP_0002140
Disease	hemifacial microsomia	PARD3B AGAP1	4.31e-03	19	153	2	MONDO_0015398
Disease	PR interval	CRYBG2 MYCBP2 CUL9 TGIF1 BMPR2 LDB3 ALPK3 MACF1	4.42e-03	495	153	8	EFO_0004462
Disease	tea consumption measurement	CUL9 PKMYT1 MSH6 SUGP1	4.63e-03	129	153	4	EFO_0010091
Disease	neutrophil percentage of leukocytes	CEBPD TSPOAP1 ZNF689 DUT ZC3H18 GMIP SCML4 ATXN2 SNAPC4	4.68e-03	610	153	9	EFO_0007990
Disease	mean corpuscular hemoglobin concentration	TTC28 FCHO2 ZNF767P SPECC1 SH2B1 ARHGEF15 TGIF1 TTBK2 BMPR2 ATXN2 BRD4 MACF1 AGAP1	5.08e-03	1105	153	13	EFO_0004528
Disease	vital capacity	HMGA1 ADAMTS8 SH2B1 TBX18 NCOR2 DST TULP4 MTF1 NFATC4 BRD4 SNAPC4 VWA5B1 AGAP1 AGAP3	5.12e-03	1236	153	14	EFO_0004312
Disease	sexual dimorphism measurement	ITCH KMT2B RASGRF1 DUT HMGA1 NFS1 NCOR2 NFATC4 ALPK3 MACF1 MGA EPB41L1 AGAP2	5.12e-03	1106	153	13	EFO_0021796
Disease	urate measurement, bone density	TTC28 WDR7 HCN2 FNDC1 LARP4B BCL11B PLXNC1 TAF4B DCLK1	5.14e-03	619	153	9	EFO_0003923, EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
APCSRRPAPGKASGP	AEN	91	Q8WTP8
VPGKRLPRATPATAP	AGAP3	426	Q96P47
PQLRAAPPTRTPSAK	BRWD1-AS2	11	P59051
GPPGTSALPRLSRSP	MLLT6	581	P55198
RLSPLPPGSPGSAAR	AEBP2	16	Q6ZN18
RPSPRTVKSFPLAAP	ARHGEF10L	846	Q9HCE6
AAQRSGPRAPSPTKP	CDCA5	11	Q96FF9
GPRAPSPTKPLRRSQ	CDCA5	16	Q96FF9
PGKRPPRATSACAPI	AGAP1	406	Q9UPQ3
SPVSNKAGPSPPRRG	ARAP3	686	Q8WWN8
RALSGRKGPAAPPPT	CAVIN3	191	Q969G5
SRPSNRAAALPPKPA	BRD4	871	O60885
PPPPLGATSRTKRFV	ADAMTS8	201	Q9UP79
RRPKLEAPPSPSLGS	CARMIL2	1386	Q6F5E8
TPGPSSPRQPRKALV	ARHGEF5	1121	Q12774
VPPPRPASRPKLTSG	FCHO2	461	Q0JRZ9
PTVSPRGPRKSLVPG	ALPK3	1391	Q96L96
ARSKSAPRAPPGLTP	AJM1	91	C9J069
ALAAGSPARPPPARS	AJM1	851	C9J069
GSARKRSSPKGPPLP	CEP41	281	Q9BYV8
VPRGPSNPRKSVSSP	SPECC1	121	Q5M775
PGKRPPRAISAFGPS	AGAP2	736	Q99490
KPPALLPPSASRASL	ARHGEF15	71	O94989
KLPAASPRHIRPSGP	FAM186B	811	Q8IYM0
RTPRQPPRGPSAAAK	FBXL6	66	Q8N531
ARHPASSVALKRPPP	ADAM8	736	P78325
LGSRRKPAAPPPSPA	CEP170B	1076	Q9Y4F5
KGFQPPSPSLRPRPA	DMRTC1;	161	Q5HYR2
GPKAASPSPARRVPA	CAMSAP3	751	Q9P1Y5
RAPSPSGLMSPSRLP	CAMSAP3	1071	Q9P1Y5
KSRPPNSVLPRPSSA	ATXN7L1	391	Q9ULK2
PAPARPRSPSQTRKG	AMPH	286	P49418
PPKRSAPSGPVRSSS	RBMX	161	P38159
AGSLPTPPVPRHRKS	RALGPS1	326	Q5JS13
TAHTTGPPPKPRRSK	TSPOAP1	1726	O95153
AVSPRKSPRPAGPQL	PAXX	146	Q9BUH6
PSPEPSPFGSRTKKR	FHIP1B	581	Q8N612
GSSPRGKSRSPAPPA	NCOR2	1016	Q9Y618
KSPRVPRLGGKPSSP	PARD3B	351	Q8TEW8
RRLPSSPASPSPKGT	EPB41L1	536	Q9H4G0
KPKRGVPTSASAPPR	KIAA0100	1501	Q14667
TPGKGPADRASRAPP	MAP1A	2631	P78559
APPKRPAVASARPSI	MAP4	751	P27816
PKGSIRPSISNPRIP	GOLGA1	751	Q92805
PGPPRASLRAKTSPE	LDB3	161	O75112
AAPGPKPAAPTRGLR	NFS1	16	Q9Y697
PRTPAKVPTSAPSLG	NCKAP5L	791	Q9HCH0
FVPAKRPIAARPSPG	MGA	1521	Q8IWI9
PTLLRPPDGPRAASA	GMIP	716	Q9P107
PTPRAGSRPSTAKPS	DST	7536	Q03001
RQKPPAPRASGGPAL	FOXL2NB	81	Q6ZUU3
PSPKRTSVGSRPPAV	FSD1L	346	Q9BXM9
APPAAPTRASPLGAR	ATXN2	116	Q99700
ASPPRSGVSLARPAP	ATXN2	131	Q99700
VAKSEPARPSPGSPR	KCNN1	46	Q92952
PPALKSTPGAPRDQR	LARP4B	696	Q92615
PSPSPTSPGSLRKQR	DCLK1	331	O15075
PHTRATRTKPCGLPP	CCDC120	506	Q96HB5
APAPALPPTGDKTSR	DUSP2	146	Q05923
AGSKAELPPTVSRPP	IRAG1	366	Q9Y6F6
EPPSMRLKARPSSPG	FCGRT	201	P55899
VSLAPPARPRPGSSF	PLXNC1	91	O60486
ARSPRRPGAPSLSPA	DCAF10	51	Q5QP82
RPGPGPRSASASLLP	GPR153	486	Q6NV75
APVPSRRNPPGGKSS	JPT1	136	Q9UK76
EGRSSSPVPPPRLKA	LCA10	106	Q71F78
PARGGRKPSPPEAAS	KIF26A	871	Q9ULI4
KRPAPRAPSASPLAL	MICALL1	476	Q8N3F8
SPPPVVPATCSRKRG	KMT2B	456	Q9UMN6
KRPLAAPSAPTVAAP	FAM181B	126	A6NEQ2
PSTTPHSSPKQRPRG	KIAA1191	176	Q96A73
PGPETPAISPSKRAR	DUT	91	P33316
GPRPLARSASPPKAK	MSH6	56	P52701
LSPPPEAAPRGGRKT	IRX2	296	Q9BZI1
SLRPPGAPATFLRPS	MEF2B	286	Q02080
RSGGRKSLSQPTPPP	MACF1	6961	Q9UPN3
PSLSNGGFKPSRPPR	ITCH	241	Q96J02
ATRASPPRSPAEPKG	C6orf132	271	Q5T0Z8
TSGSPRSPAGPEKPR	APC2	1761	O95996
SQPPRSATPPARLAK	APC2	1856	O95996
RKPAPLPSPGLNSAA	BCL11B	671	Q9C0K0
ARKSSGQPGRLPPPT	BOC	811	Q9BWV1
SSPRQTPAPGPAREK	CEBPD	166	P49716
PRSGKTPASIRKPPS	GAS2L3	646	Q86XJ1
PSRAAPGKSEPPSKR	FNDC1	1151	Q4ZHG4
KAGPSPSRDLHPARP	CRYBG2	851	Q8N1P7
LKLRSPDASPSRAPP	GNAS	166	O95467
PSTAADPGPSKPRRA	BMPR2	921	Q13873
APSGLFSKRRAPGPP	C2CD4D	21	B7Z1M9
ARASTSSPKPLVPRP	C19orf67	61	A6NJJ6
RSKQAGSSPRPPPGL	AKNA	1311	Q7Z591
RPVKFPSLPRSPASS	ANKS6	611	Q68DC2
RGPRGTVAPATPTKP	COL27A1	286	Q8IZC6
PFSGTTPSRKPLPKR	EDDM13	101	A0A1B0GTR0
SPPRPRTGLPQGKKS	CRIP3	96	Q6Q6R5
GPSRRPASLSPAAPA	HES4	151	Q9HCC6
AALAAGPTPPGPRKR	LYL1	211	P12980
IKVPPRSPRSTIGSP	MBD5	486	Q9P267
SKGRDRSPAPSPVLP	CUL9	1451	Q8IWT3
STLRGKPRPPPVSAQ	C5orf49	11	A4QMS7
LPASPAPRAARKASP	CCDC177	196	Q9NQR7
ALGPASSTPRPLARP	EMILIN1	136	Q9Y6C2
SRPAAGKPRPPPSQL	SAC3D1	101	A6NKF1
SLTGLPPPVSRRPGS	CEP131	21	Q9UPN4
PPPVSRRPGSAATTK	CEP131	26	Q9UPN4
PRLGPTPAARAAAPS	HCN2	846	Q9UL51
PRTLPGSRHKPAPTK	CABLES2	271	Q9BTV7
VSPAAGSSPGKPPRL	CST3	21	P01034
KVAPAPARPSGPSKA	ARCN1	211	P48444
GSRAPPGRLLPSAPT	KIFC2	766	Q96AC6
PGTPRPLNRPKVSLS	PPP4R2	171	Q9NY27
DKSRSPRSPPGKPQG	PRB2	106	P02812
RGRPRKQPPVSPGTA	HMGA1	26	P17096
AAGTLPSPQSLRKPP	MPP3	301	Q13368
TSTPGASPAPRSRKP	MIDN	251	Q504T8
VSAPPKVSSGPRLPA	TAF4B	76	Q92750
PPKASRPRLSIPCSS	SH2B1	311	Q9NRF2
SPRKGAAPAPPRKTG	TCOF1	446	Q13428
TPASPRPASPCGKRR	NFATC4	256	Q14934
GKSPRLCRKFSSPPP	RASGRF2	716	O14827
ASSRRKGCSSPPPPE	MTF1	646	Q14872
SPASAGLRRNPALPP	PRDM15	166	P57071
TPPRKDAAPALGPLS	PRR36	286	Q9H6K5
SPGRAPAPSALPRAK	GPR150	276	Q8NGU9
PKTNSLSRPGALPPR	SH3KBP1	406	Q96B97
PSRASKGPGPTARAP	SORCS2	6	Q96PQ0
TPRDSAGVSPFPPKR	PRRC2A	1546	P48634
PALNPTRAPKASRPP	SLITRK2	291	Q9H156
PLRGRSTSPKPKSVP	MYCBP2	2891	O75592
PGSRAPSPRLPNKTI	WIPF3	126	A6NGB9
PRATRKFSSPPPLSI	RASGRF1	731	Q13972
PPRSRKPSKAGTAPS	SOWAHB	526	A6NEL2
SPGPRSPKAPPSSRL	ARHGAP4	901	P98171
PATSASPPGPTLKAR	C15orf39	991	Q6ZRI6
RKPNSRPAPGVGSLP	PRDM10-DT	116	Q96N53
APTCPRTPKPTSRGR	ZNF837	176	Q96EG3
RKSPPEALSGSLPPA	SUGP1	336	Q8IWZ8
LPKPPRSPSRSPSHS	INPP5J	341	Q15735
SPKPSSPGSVLARPS	TGIF1	286	Q15583
PSPSPRSSPRLNKGR	ZNF767P	111	Q75MW2
RSPTAPFTSPLPRGK	PEX11G	156	Q96HA9
SAKACTPDGPRPRPR	VWA1	416	Q6PCB0
PRLPLRKPSVGSPSL	TULP4	566	Q9NRJ4
PSPTASGRAALAPRP	WDR90	276	Q96KV7
PPASLRSSVPPSKRG	RGS12	511	O14924
AAAVPTTPRRGRPPK	SPEN	1941	Q96T58
SALLPPPSPRVGKRS	SPEG	306	Q15772
KARVPTVPPRPGSSL	SPEG	2306	Q15772
PAKGSIPISRLFPPR	PKMYT1	56	Q99640
SPARSLARPGTPLPS	TBX18	121	O95935
RGPSPAPASSPKREV	SCAF1	716	Q9H7N4
PAPGTALPAPDRKRF	RNF123	1196	Q5XPI4
PKSPVVPRRSPSASP	TTBK2	1141	Q6IQ55
KSRSPSPRSLPPALS	SPCS1	46	Q9Y6A9
TPSRTAPGALTAKPP	TBC1D10B	156	Q4KMP7
SKPGPISRPVTISRP	ZNF512B	171	Q96KM6
PATAPARPLRLPSGN	TTC28	2451	Q96AY4
APLPAQGPGKARPSR	ZNF689	6	Q96CS4
PQASLLASTGPRPKP	SNAPC4	876	Q5SXM2
SSGPSPGPSVPRLRL	SEMA3G	21	Q9NS98
PATRSPFPPGKSRTS	USP31	1136	Q70CQ4
PSSRRGLNGTKPVPP	TOGARAM1	901	Q9Y4F4
PPRPSTPDLSKARGS	WDR7	921	Q9Y4E6
AAPSRPGAPAAGPRK	WWC2-AS2	31	Q96NR7
SSAGEVPKPRPPSTR	ZNF185	66	O15231
SAPGLRPPASSPKRN	SCML4	301	Q8N228
AKHSRPASPDPTPGR	ZDHHC1	336	Q8WTX9
TPSPHRPSIRTKGEP	ZC3H18	611	Q86VM9
RASPSRPATPAPVLG	VWA5B1	796	Q5TIE3
PLASSPESARPKPRA	KMT2D	4951	O14686
TPALGPSAPQKPLRR	KIAA1522	841	Q9P206
ARATPAPKGIPASPS	NACA	921	E9PAV3