Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionphosphatidylinositol binding

OBSCN ZCCHC2 PHLDA1 CERT1 TPCN1

2.11e-04316355GO:0035091
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

OBSCN PHLDA1 CERT1 TPCN1

3.93e-04199354GO:1901981
GeneOntologyCellularComponentaxon cytoplasm

BLOC1S1 DST DYNC1H1

2.18e-0468363GO:1904115
DomainTAS2R

TAS2R45 TAS2R46

1.14e-0326362PF05296
DomainT2R

TAS2R45 TAS2R46

1.14e-0326362IPR007960
Domain-

HCFC1 KLHL20

1.23e-03273622.130.10.80
DomainGal_Oxidase_b-propeller

HCFC1 KLHL20

1.95e-0334362IPR015916
DomainFN3

OBSCN NCAM2 HCFC1

5.37e-03185363SM00060
DomainGal_Oxase/kelch_b-propeller

HCFC1 KLHL20

5.77e-0359362IPR011043
DomainFN3

OBSCN NCAM2 HCFC1

6.57e-03199363PS50853
DomainCH

ASPM DST

6.96e-0365362SM00033
DomainFN3_dom

OBSCN NCAM2 HCFC1

7.52e-03209363IPR003961
DomainKelch_1

HCFC1 KLHL20

8.03e-0370362PF01344
DomainKelch_1

HCFC1 KLHL20

8.03e-0370362IPR006652
DomainCH

ASPM DST

8.03e-0370362PF00307
DomainIQ

OBSCN ASPM

8.26e-0371362PF00612
Domain-

ASPM DST

8.26e-03713621.10.418.10
DomainCH

ASPM DST

8.71e-0373362PS50021
DomainIGv

OBSCN NCAM2

9.18e-0375362SM00406
DomainCH-domain

ASPM DST

9.18e-0375362IPR001715
DomainIQ

OBSCN ASPM

1.06e-0281362SM00015
DomainIQ_motif_EF-hand-BS

OBSCN ASPM

1.30e-0290362IPR000048
DomainIQ

OBSCN ASPM

1.38e-0293362PS50096
Pubmed

Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.

OBSCN PRUNE2

1.04e-06236217360660
Pubmed

EGF/TGFβ1 co-stimulation of oral squamous cell carcinoma cells causes an epithelial-mesenchymal transition cell phenotype expressing laminin 332.

LAMA5 EGF

3.12e-06336220819124
Pubmed

Structure and function of hemidesmosomes: more than simple adhesion complexes.

LAMA5 DST

1.04e-05536210201522
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

OBSCN LAMA5 DST TTC5 HCFC1 DYNC1H1 RIC1 TPCN1

1.39e-05110536835748872
Pubmed

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.

ACADM UCP2

5.70e-051136215616563
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

LAMA5 DST

5.70e-05113628707838
Pubmed

The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides.

TAS2R45 TAS2R46

6.83e-051236212379855
Pubmed

Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.

LAMA5 DST

8.07e-05133629670011
Pubmed

Haplotypes at the Tas2r locus on distal chromosome 6 vary with quinine taste sensitivity in inbred mice.

TAS2R45 TAS2R46

8.07e-051336215938754
Pubmed

Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.

EPO ACTL6B

8.07e-051336211239002
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

ASPM BLMH DYNC1H1

9.16e-058436329563501
Pubmed

Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.

EPO ACTL6B

9.41e-05143629799793
Pubmed

A novel family of mammalian taste receptors.

TAS2R45 TAS2R46

2.16e-042136210761934
Pubmed

Evolutionary relationships of the Tas2r receptor gene families in mouse and human.

TAS2R45 TAS2R46

2.38e-042236212734386
Pubmed

The molecular receptive ranges of human TAS2R bitter taste receptors.

TAS2R45 TAS2R46

2.60e-042336220022913
Pubmed

Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.

ACADM UCP2

3.08e-042536223968980
Pubmed

Receptors for bitter and sweet taste.

TAS2R45 TAS2R46

3.08e-042536212139982
Pubmed

Molecular mechanisms of bitter and sweet taste transduction.

TAS2R45 TAS2R46

3.33e-042636211696554
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

DST COG1 DYNC1H1 KLHL20

3.36e-0432236426514267
Pubmed

Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.

TAS2R45 TAS2R46

3.60e-042736212581520
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

OBSCN DST ACADM DYNC1H1

3.73e-0433136429199018
Pubmed

Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.

TAS2R45 TAS2R46

3.87e-042836215744053
Pubmed

Global analysis of gene expression in the developing brain of Gtf2ird1 knockout mice.

PRUNE2 ACTL6B

4.16e-042936221909369
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

ASPM SLC12A8 DST

4.31e-0414236311812828
Pubmed

Adaptive diversification of bitter taste receptor genes in Mammalian evolution.

TAS2R45 TAS2R46

4.45e-043036212679530
Pubmed

Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.

TAS2R45 TAS2R46

4.45e-043036217273929
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

DST ACADM ERCC6L HCFC1 RIC1

5.24e-0465036538777146
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

ASPM LAMA5 DST TOP1

5.28e-0436336414691545
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

BLMH N4BP2L2 ACADM CERT1 HCFC1 KLHL20

5.32e-04100536619615732
Pubmed

Tandem immunoprecipitation of phosphotyrosine-mass spectrometry (TIPY-MS) indicates C19ORF19 becomes tyrosine-phosphorylated and associated with activated epidermal growth factor receptor.

EGF HCFC1

5.39e-043336218271526
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DST ERCC6L HCFC1 TOP1 DYNC1H1

7.71e-0470836539231216
Cytoband7q22

EPO ACTL6B

3.90e-04383527q22
GeneFamilyTaste 2 receptors

TAS2R45 TAS2R46

1.43e-03392621162
GeneFamilySolute carriers

SLC34A2 SLC12A8 UCP2

1.85e-02395263752
GeneFamilyFibronectin type III domain containing

OBSCN NCAM2

2.20e-02160262555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN NCAM2

2.23e-02161262593
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM MED12L EGF MYZAP GP1BA

3.45e-0718735569068480f6819a6c8560ecbb05deb156b4055e12
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM MED12L EGF MYZAP GP1BA

3.45e-071873559c8b932a15b8b50982cba4cf8db750e257eb9503
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM MED12L EGF MYZAP GP1BA

3.45e-0718735546e15419e80bd7180f3171a99d845b01bb635e53
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ASPM MED12L EGF MYZAP GP1BA

3.45e-071873550d17b07770e4c881a7ca53a5bd42471457d198fb
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.31e-051853549bff336510c80cd762b4e41b4570475033e709ca
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.31e-05185354452d49c7835a4d55e41caefa44dac5cab30e7ced
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic-Megakaryocytic-Megakaryocyte|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.31e-0518535453f5136ee1bd101dd5ac8a2c9e63b0c3b987657e
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Hematopoietic-Megakaryocytic|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.31e-0518535467ac5c2bacdbdcb40ee65c44da55b3f597b410ee
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.34e-051863549e2e8e2c3de711734cdb4775bafb0757b4db97b1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.34e-051863541dfd3fc4012bf0254adfa1f5eddadc9b6107455b
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.34e-051863548fbf5cb31192066b4c202f80baf6d7f2bdefedb9
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Hematopoietic-Megakaryocytic|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.34e-0518635449d23c985b2f5e16790f4d7ccf81ef7b794c0877
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.37e-05187354644d49bf66745d2e2d0f9bb3290d3e60c4ca7c4a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.37e-05187354ff84f75c10037f27c1f56eb1accd150cfe52f8e4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.37e-05187354854ef90afa59b18ee9f38cfb4659808b79c25202
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L EGF MYZAP GP1BA

1.37e-05187354eac261f16d3a9e9213199872dffccb9f4e1d6f18
ToppCelldroplet-Kidney-KIDNEY-1m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTOV1 DST EGF ACADM

1.58e-05194354837cee7e6147d92a2f4b86f1ed761a9bfe65b61d
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland-SMG_Mucous|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SLC12A8 EGF TAS2R46 ZCWPW2

1.71e-051983542ae9564da9913510141994262f3739eb095e0a68
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ASPM MED12L TOP1 UCP2

1.78e-05200354fa1eaf008b54bdf7bbcdec8134460c5f64490de9
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ASPM MED12L EGF UCP2

1.78e-05200354f99e214eb680fd82a33f2b1524fbfca265d1cc42
ToppCellLPS_IL1RA-Hematopoietic_Erythro-Megakary|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ASPM MED12L EGF UCP2

1.78e-05200354d85074b362b11e5a523a5325d203a61aa2759a7a
ToppCellLPS_only-Hematopoietic_Erythro-Megakary|LPS_only / Treatment groups by lineage, cell group, cell type

ASPM MED12L TOP1 UCP2

1.78e-05200354ce8281c9556a1f64f8ca8a029110077d4ef5b35e
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_only / Treatment groups by lineage, cell group, cell type

ASPM MED12L TOP1 UCP2

1.78e-0520035483c4181c083b364f0d3a89ae7a0504781fa9fa9f
ToppCellLPS_only-Hematopoietic_Erythro-Megakary-Erythro-Mega|LPS_only / Treatment groups by lineage, cell group, cell type

ASPM MED12L TOP1 UCP2

1.78e-05200354f15baf287ec467664c23faa53fdea45257f7b9d0
ToppCellFetal_29-31_weeks-Immune-mast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MED12L ACTL6B EGF

1.99e-04145353dc89d817a9bef24a07e992efdab4136f12ceb399
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

PRUNE2 EPO DST

2.47e-041563539a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellGoblet|World / Class top

SLC34A2 SLC12A8 EGF

2.51e-04157353b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCellFetal_29-31_weeks-Immune-mast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MED12L EGF GP1BA

2.56e-041583530c27c475289c70b17b6a66fc71f628511c5f0ae1
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYZAP KLHL20 TPCN1

2.61e-04159353709b57f992a29878cc899d760d144d36cb5cb280
ToppCelldroplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NCAM2 EGF

2.71e-04161353f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCelldroplet-Lung-nan-3m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 NCAM2 EGF

2.71e-04161353110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC34A2 MYZAP TPCN1

2.76e-04162353bc63a96ad3ba0b3433e3679d7a005f47709ff384
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

MED12L EGF GP1BA

2.76e-04162353e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCellFetal_29-31_weeks-Immune-mast_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MED12L EGF GP1BA

2.81e-0416335303b2ec226adffba3ce893f3d12e549c841e662fd
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MED12L EGF GP1BA

2.91e-04165353d2ab667ff53f538b12ee4e07ea4b4d118600a228
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM MED12L UCP2

2.91e-04165353cece16b03282d27fb49102eb9c104a2024efd28c
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

3.07e-041683532f69e248c6fab1421c0081e01e1920e6ffcde344
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

3.07e-041683532d056cfbb470a088a0682576753535fb4528d48f
ToppCellwk_15-18-Hematologic-Meg-ery-Megakaryocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MED12L EGF GP1BA

3.12e-04169353d571e84e01e3316748d4407ed98881b17484e035
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte2_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MED12L EGF GP1BA

3.17e-041703533886a77bc3ddbeb42a8149b759fe578871676d6e
ToppCellwk_20-22-Hematologic-Meg-ery-Megakaryocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MED12L EGF GP1BA

3.17e-04170353eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OBSCN DST MYZAP

3.17e-04170353af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCellwk_08-11-Hematologic-Meg-ery-Megakaryocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MED12L EGF GP1BA

3.23e-041713539dda25df493766723335851b3c3d89735b6e8051
ToppCellCOVID-19-lung-RBC|lung / Disease (COVID-19 only), tissue and cell type

MED12L EGF GP1BA

3.23e-041713530e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

OBSCN DST MYZAP

3.28e-041723539a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ASPM MED12L UCP2

3.34e-04173353b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EGF UCP2 GP1BA

3.45e-04175353c33317d8d60ea88ec326daf91dfd3416a62f9938
ToppCellCOVID-mDC1-|COVID / Condition, Cell_class and T cell subcluster

MED12L LAMA5 MYZAP

3.45e-0417535383a95d6fc2ddf3ec53f05825bbc982fb8d2ccd15
ToppCellCOVID-mDC1|COVID / Condition, Cell_class and T cell subcluster

MED12L LAMA5 MYZAP

3.45e-04175353b9280444016e21c28131a61df65cc5c56d402412
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ASPM ERCC6L UCP2

3.45e-04175353f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MED12L EGF GP1BA

3.45e-04175353b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tnaive/CM_CD4|GI_large-bowel / Manually curated celltypes from each tissue

OBSCN TIGD2 ZCWPW2

3.57e-04177353eb87ea93e36a8f97442ec8515f658ee61932dc0f
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ASPM SLC12A8 ERCC6L

3.57e-041773534197cf2b1e743230c821f422836fa5991b155a52
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L MYZAP GP1BA

3.63e-041783535caeffb70cbb868586bd260b44ccd3751bbfa615
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L MYZAP GP1BA

3.63e-041783532c581a338bf33dbd2be9abe87d0a84f97dfb546f
ToppCellIIF-Other-Platelet|IIF / Disease, Lineage and Cell Type

EGF MYZAP GP1BA

3.63e-04178353529c0d2159e539546876246122f2e999170a6b20
ToppCellE17.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

OBSCN DST MYZAP

3.63e-041783530139b42494c1186390b12106dea7957e2b6717c2
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic-Megakaryocytic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L MYZAP GP1BA

3.63e-04178353afc3220e2319cb38d59307db1b793a3915e1d5c4
ToppCellPBMC-Convalescent-Hematopoietic-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

3.63e-04178353f5d83ad082e31d5601890d245b9fb4f9ef6a062b
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

3.63e-04178353a2a8fc14f492a4695e6991a357b6626145f1bf7f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Hematopoietic|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MED12L MYZAP GP1BA

3.63e-041783534ff23a0bb20c4373db14bfaad18b5fa5c7c78e76
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

3.69e-04179353510927794bbd21814eba75286e0801eb1fd2e8a6
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA5 DST EGF

3.69e-04179353a09647750eba9d93c5efc1db3b555fefb5eec7b5
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

EGF MYZAP GP1BA

3.69e-041793533b1616e974ea7792ff5c37da3b0281f28edfbb56
ToppCellPBMC-Convalescent-Hematopoietic|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

3.69e-0417935335271a4396a533f6d960ce55d171a32d9d2fd1a4
ToppCellPBMC-Convalescent-Hematopoietic-Platelet|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

3.69e-04179353906a5ebbbac660b6fd498ced09d0ada40a3e64af
ToppCellCOVID-19_Convalescent-Hematopoietic_Mega-Platelet|COVID-19_Convalescent / Disease group, lineage and cell class

EGF MYZAP GP1BA

3.75e-04180353deed53167504c91220b35a63366ed7d8f02a5254
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

3.75e-041803535568063c2518fadb638e665635061ec10d00fb6a
ToppCellPBMC-Mild-Hematopoietic-Platelet-Platelet-plt_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

3.75e-041803531be264962fd4ed0bb59f9b8a6956c4239ca32e05
ToppCellCOVID-19_Convalescent-Hematopoietic_Mega|COVID-19_Convalescent / Disease group, lineage and cell class

EGF MYZAP GP1BA

3.75e-0418035317323d382ae322e388e230fdad13e3464ea73e8e
ToppCell3'_v3-bone_marrow-Hematopoietic_Erythro-Mega-Erythrocytic-Meg|bone_marrow / Manually curated celltypes from each tissue

MED12L EGF GP1BA

3.75e-0418035344ba37bead1ac39bce4d3eef00961063c50ced0d
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-5|TCGA-Breast / Sample_Type by Project: Shred V9

EPO ERCC6L TOP1

3.87e-041823539e48d5b634603bc7a8d29290202a311457678328
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega-Mega-Mast|blood / Manually curated celltypes from each tissue

MED12L EGF GP1BA

3.87e-041823531923b5669901f828e890416c22d1f1d21a4a2c6a
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN MYZAP ACADM

3.87e-04182353c4a7007c864a9455a7e7447e28ccd380878a6a0f
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

MED12L EGF GP1BA

3.87e-041823533100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCell18-Distal-Immune-Hematopoietic,_B_Cells|Distal / Age, Tissue, Lineage and Cell class

MED12L EGF UCP2

3.87e-04182353cd0b9f0a25147ec3bc1e32d698511d1c3b33891f
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EGF UCP2 GP1BA

3.87e-04182353e5e16abf4d3bd5a97e7c573b99f7a3d9a5add120
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN MYZAP ACADM

3.87e-04182353c315d820ffad912c014ba5eac6f5fa6de1a94384
ToppCellremission-Platelet|remission / disease stage, cell group and cell class

EGF MYZAP GP1BA

3.87e-0418235365e2798aacd670cbc3a8c8e9d1a2f7768513bb70
ToppCellBasal|World / shred by cell class for mouse tongue

LAMA5 DST UCP2

3.94e-04183353c6729a207526ff4aa48176207b9353176f631fea
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MED12L EGF GP1BA

3.94e-041833539c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCellCalu_3-infected|Calu_3 / Cell line, Condition and Strain

N4BP2L2 DST ZCCHC2

3.94e-041833538f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

MED12L EGF GP1BA

3.94e-041833536cbc88c27dc957d182526e84824f70c8e860bf74
ToppCell10x3'2.3-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MED12L EGF GP1BA

4.00e-04184353ba65e3972b2b8d825a2c1a9d03d092cc1afad073
ToppCell15-Distal-Immune-Hematopoietic,_B_Cells|Distal / Age, Tissue, Lineage and Cell class

EGF UCP2 GP1BA

4.00e-04184353c294cd421f277992b56ae9c40b8f3948e33148fe
ToppCellcontrol-Others-Megakaryocytes|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EGF MYZAP GP1BA

4.00e-04184353213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCellcontrol-Others|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

EGF MYZAP GP1BA

4.00e-04184353a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCellmegakaryocytic|World / Lineage and Cell class

MED12L EGF GP1BA

4.00e-04184353b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 SLC12A8 DST

4.06e-041853531c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellURO-Lymphocyte-T_NK-T_NK_proliferative|URO / Disease, Lineage and Cell Type

ASPM TAS2R46 ERCC6L

4.06e-041853530ae9c646679c69a553eda670aef0e0495feb0286
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

LAMA5 SLC34A2 ZCWPW2

4.06e-041853530563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCellPBMC-Severe-Hematopoietic-Platelet-Platelet-plt_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

4.06e-04185353698ff44fd2d9b3ad5cea45f4cff9bfc64c559b62
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

4.06e-04185353709236097cbfc254796fcc69b5f5178b73dad9bd
ToppCellPBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

4.06e-04185353af078a6c4a3e0b54b7d8ab7b30dcd06053ebfd28
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

4.13e-0418635306281df5e9665ccc510279bf7e552845c63d5dab
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

EGF MYZAP GP1BA

4.13e-041863533bf38c80d892a73391009b426dec8ae26a027351
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

4.13e-04186353107bc473f5e57238390f8e0ab9f7263a8f93948c
ToppCellPBMC-Control-Hematopoietic-Platelet|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

EGF MYZAP GP1BA

4.13e-041863537496137cebc191aecd1e6ae7fa33118b128fbfe6
ToppCellPBMC-Control-Hematopoietic-Platelet|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGF MYZAP GP1BA

4.13e-041863539c2fd0bbc968c317a763f52e72fa7182c3c49850
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGF MYZAP GP1BA

4.13e-0418635313a9ddcf93b0c4319ab9d484af5e2056e9754caa
DrugGW8510; Down 200; 10uM; PC3; HT_HG-U133A

ASPM N4BP2L2 ERCC6L PHLDA1 KLHL20

9.53e-061823657067_DN
DrugEllipticine [519-23-3]; Down 200; 16.2uM; MCF7; HT_HG-U133A

N4BP2L2 ZCCHC2 ERCC6L KLHL20 UCP2

9.53e-061823656253_DN
Drughistidinol

BLMH TOP1 UCP2

1.16e-0528363CID000000776
Drugbiotinamidocaproyl hydrazide

EPO EGF

1.46e-054362CID000083900
Diseasediabetic neuropathy (is_implicated_in)

EPO UCP2

1.16e-0414342DOID:9743 (is_implicated_in)
DiseaseGastric ulcer

EPO EGF

1.95e-0418342C0038358
DiseaseDisease Exacerbation

PTOV1 EGF TOP1

9.05e-04165343C0235874
Diseasemean platelet volume

EPO N4BP2L2 ACTL6B CERT1 UCP2 GP1BA

9.86e-041020346EFO_0004584
Diseasehigh grade glioma (is_implicated_in)

EPO EGF

1.08e-0342342DOID:3070 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
AQFAKQTGQWIGMVE

BLOC1S1

96

P78537
GTFQQMWISKQEYEE

ACTL6B

401

O94805
DEYIINGQKMWITNG

ACADM

181

P11310
AVQSEGVMIQEWYKA

ASPM

2786

Q8IZT6
WKLFGNITQEQNMIV

RIC1

526

Q4ADV7
ANWQLVVEEGEMKVY

CERT1

416

Q9Y5P4
QWFDVGVIKGTNVMV

HCFC1

1811

P51610
PEVEQAMKQWEYNEK

MED12L

221

Q86YW9
ANDVEVKWIEYQNMV

DST

266

Q03001
TGVWLYVDDQLQQMK

LAMA5

3211

O15230
QIVNNKFLAWSGVME

PTOV1

251

Q86YD1
VAQAQTEVMWYKDGK

OBSCN

1006

Q5VST9
VAQAQTEVMWYKDGK

OBSCN

1466

Q5VST9
VFNAVMAWVKYSIQE

KLHL20

231

Q9Y2M5
KEVLLQQSVMGYQVW

COG1

671

Q8WTW3
KNVSGMAINWINEEV

EGF

116

P01133
YAWKRMEVGQQAVEV

EPO

76

P01588
QWDMLVNIVEKYGVI

BLMH

146

Q13867
ENVYVWKQGVDVKAM

GP1BA

241

P07359
GMWVEKVLQLYQITQ

DYNC1H1

2201

Q14204
VIQWVYTLVNMGVAA

SLC12A8

611

A0AV02
GVIITTYQMLINNWQ

ERCC6L

196

Q2NKX8
VVNMNQIVWTKEYEG

TAS2R45

146

P59539
VINMNQIIWTKEYEG

TAS2R46

146

P59540
NQWEQEKSYLGEMTN

PRUNE2

1996

Q8WUY3
DGIQNWTMKNVTYKE

SLC34A2

331

O95436
MQYSEQNGIVDWRKQ

ZCCHC2

531

Q9C0B9
RVMIEWFNQQKTDGI

TIGD2

81

Q4W5G0
GSWNVVMFVTYEQLK

UCP2

281

P55851
LQWTMGYEVQITAAN

NCAM2

656

O15394
GWNAEITLQMVQYKN

PHLDA1

271

Q8WV24
AVMVYNIVQSWGVLI

TTC5

366

Q8N0Z6
VNNWYIIMEGVTSQT

TPCN1

646

Q9ULQ1
VENMYVNKVWVQCEN

ZCWPW2

21

Q504Y3
WTENIQGSIKYIMLN

TOP1

416

P11387
DNTNIQAWEMKPYVE

N4BP2L2

476

Q92802
QNQQKEMVVYGWSTS

MYZAP

81

P0CAP1