Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	diacylglycerol-dependent serine/threonine kinase activity	PRKCA PRKCB PRKCE PRKCH	2.22e-08	16	39	4	GO:0004697
GeneOntologyMolecularFunction	histone H3T6 kinase activity	PRKCA PRKCB	3.72e-06	2	39	2	GO:0035403
GeneOntologyMolecularFunction	diacylglycerol-dependent, calcium-independent serine/threonine kinase activity	PRKCE PRKCH	1.11e-05	3	39	2	GO:0004699
GeneOntologyMolecularFunction	histone H3 kinase activity	PRKCA PRKCB	2.42e-04	12	39	2	GO:0140996
GeneOntologyMolecularFunction	glycosphingolipid binding	LAMB1 LAMA1	2.86e-04	13	39	2	GO:0043208
GeneOntologyMolecularFunction	muscle alpha-actinin binding	LDB3 NRAP	3.84e-04	15	39	2	GO:0051371
GeneOntologyMolecularFunction	protein-hormone receptor activity	LEPR INSR	8.38e-04	22	39	2	GO:0016500
GeneOntologyMolecularFunction	protein serine/threonine kinase binding	PRKCE PRKCH	9.98e-04	24	39	2	GO:0120283
GeneOntologyMolecularFunction	histone modifying activity	PRKCA PRKCB SMYD5 CREBBP	1.01e-03	229	39	4	GO:0140993
GeneOntologyMolecularFunction	protein kinase binding	PRKCB PRKCE PRKCH ZFYVE26 LDB3 RHOBTB2 INSR	1.35e-03	873	39	7	GO:0019901
GeneOntologyMolecularFunction	histone kinase activity	PRKCA PRKCB	1.36e-03	28	39	2	GO:0035173
GeneOntologyMolecularFunction	alpha-actinin binding	LDB3 NRAP	1.67e-03	31	39	2	GO:0051393
GeneOntologyMolecularFunction	sphingolipid binding	LAMB1 LAMA1	2.00e-03	34	39	2	GO:0046625
GeneOntologyMolecularFunction	kinase binding	PRKCB PRKCE PRKCH ZFYVE26 LDB3 RHOBTB2 INSR	2.44e-03	969	39	7	GO:0019900
GeneOntologyMolecularFunction	lipid binding	LAMB1 PRKCA RASGRP4 ZFYVE26 PLA2G2C INSR LAMA1	2.72e-03	988	39	7	GO:0008289
GeneOntologyMolecularFunction	actinin binding	LDB3 NRAP	3.19e-03	43	39	2	GO:0042805
GeneOntologyMolecularFunction	glycolipid binding	LAMB1 LAMA1	4.13e-03	49	39	2	GO:0051861
GeneOntologyMolecularFunction	integrin binding	LAMB1 PRKCA VWF	4.80e-03	175	39	3	GO:0005178
GeneOntologyMolecularFunction	peptide hormone binding	LEPR INSR	5.17e-03	55	39	2	GO:0017046
GeneOntologyMolecularFunction	protein serine kinase activity	PRKCA PRKCB PRKCE PRKCH	5.35e-03	363	39	4	GO:0106310
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMB1 VWF LAMA1	5.85e-03	188	39	3	GO:0005201
GeneOntologyMolecularFunction	protein kinase activity	PRKCA PRKCB PRKCE PRKCH INSR	5.96e-03	600	39	5	GO:0004672
GeneOntologyMolecularFunction	zinc ion binding	NFXL1 PRKCA PRKCB CREBBP ZFPL1 UBR4	7.18e-03	891	39	6	GO:0008270
GeneOntologyMolecularFunction	protein kinase C binding	PRKCB LDB3	7.37e-03	66	39	2	GO:0005080
GeneOntologyCellularComponent	laminin-1 complex	LAMB1 LAMA1	1.07e-05	3	40	2	GO:0005606
GeneOntologyCellularComponent	presynaptic cytosol	PRKCA PRKCB PRKCE	1.13e-04	49	40	3	GO:0099523
GeneOntologyCellularComponent	laminin complex	LAMB1 LAMA1	1.59e-04	10	40	2	GO:0043256
GeneOntologyCellularComponent	cytosolic region	PRKCA PRKCB PRKCE	3.25e-04	70	40	3	GO:0099522
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMB1 LAMA1	4.77e-04	17	40	2	GO:0098637
GeneOntologyCellularComponent	ciliary basal body	PRKCA CAMSAP2 RTTN CDC45	5.16e-04	195	40	4	GO:0036064
GeneOntologyCellularComponent	cell-cell junction	PRKCA PRKCH LDB3 NRAP ZYX LAMA1	8.43e-04	591	40	6	GO:0005911
GeneOntologyCellularComponent	endosome	ZFYVE26 ANKRD50 DAGLA SLC36A2 RHOBTB2 UBR4 DOP1A INSR	1.43e-03	1167	40	8	GO:0005768
GeneOntologyCellularComponent	microtubule organizing center	PRKCA PRKCB ZFYVE26 CAMSAP2 UBR4 RTTN CDC45	1.62e-03	919	40	7	GO:0005815
GeneOntologyCellularComponent	calyx of Held	PRKCA PRKCB	2.16e-03	36	40	2	GO:0044305
GeneOntologyCellularComponent	centrosome	PRKCB ZFYVE26 CAMSAP2 UBR4 RTTN CDC45	3.23e-03	770	40	6	GO:0005813
Domain	DAG/PE-bd	PRKCA PRKCB PRKCE RASGRP4 PRKCH	6.04e-10	21	39	5	IPR020454
Domain	C1_1	PRKCA PRKCB PRKCE RASGRP4 PRKCH	1.18e-07	57	39	5	PF00130
Domain	ZF_DAG_PE_1	PRKCA PRKCB PRKCE RASGRP4 PRKCH	2.12e-07	64	39	5	PS00479
Domain	ZF_DAG_PE_2	PRKCA PRKCB PRKCE RASGRP4 PRKCH	2.12e-07	64	39	5	PS50081
Domain	C1	PRKCA PRKCB PRKCE RASGRP4 PRKCH	2.29e-07	65	39	5	SM00109
Domain	PE/DAG-bd	PRKCA PRKCB PRKCE RASGRP4 PRKCH	2.48e-07	66	39	5	IPR002219
Domain	Pkinase_C	PRKCA PRKCB PRKCE PRKCH	1.02e-06	37	39	4	IPR017892
Domain	Pkinase_C	PRKCA PRKCB PRKCE PRKCH	1.72e-06	42	39	4	PF00433
Domain	AGC-kinase_C	PRKCA PRKCB PRKCE PRKCH	5.51e-06	56	39	4	IPR000961
Domain	AGC_KINASE_CTER	PRKCA PRKCB PRKCE PRKCH	5.51e-06	56	39	4	PS51285
Domain	S_TK_X	PRKCA PRKCB PRKCE PRKCH	5.51e-06	56	39	4	SM00133
Domain	Protein_kinase_C_a/b/g	PRKCA PRKCB	1.27e-05	3	39	2	IPR014375
Domain	Growth_fac_rcpt_	LAMB1 ADGRE3 SLIT3 INSR LAMA1	1.75e-05	156	39	5	IPR009030
Domain	Prot_kin_PKC_delta	PRKCE PRKCH	2.54e-05	4	39	2	IPR014376
Domain	EGF	LAMB1 ADAM28 ADGRE3 SLIT3 LAMA1	1.23e-04	235	39	5	SM00181
Domain	C2	PRKCA PRKCB PRKCE PRKCH	1.57e-04	131	39	4	PF00168
Domain	EGF-like_dom	LAMB1 ADAM28 ADGRE3 SLIT3 LAMA1	1.61e-04	249	39	5	IPR000742
Domain	C2	PRKCA PRKCB PRKCE PRKCH	1.87e-04	137	39	4	SM00239
Domain	C2	PRKCA PRKCB PRKCE PRKCH	2.14e-04	142	39	4	PS50004
Domain	-	PRKCA PRKCB PRKCE PRKCH	2.51e-04	148	39	4	2.60.40.150
Domain	Zinc_finger_PHD-type_CS	SHPRH NFXL1 JADE3	3.36e-04	65	39	3	IPR019786
Domain	C2_dom	PRKCA PRKCB PRKCE PRKCH	3.71e-04	164	39	4	IPR000008
Domain	LIM	LDB3 NRAP ZYX	4.01e-04	69	39	3	PF00412
Domain	-	LDB3 NRAP ZYX	4.18e-04	70	39	3	2.10.110.10
Domain	Znf_LIM	LDB3 NRAP ZYX	4.36e-04	71	39	3	IPR001781
Domain	LIM_DOMAIN_1	LDB3 NRAP ZYX	4.36e-04	71	39	3	PS00478
Domain	LIM_DOMAIN_2	LDB3 NRAP ZYX	4.36e-04	71	39	3	PS50023
Domain	LIM	LDB3 NRAP ZYX	4.36e-04	71	39	3	SM00132
Domain	Laminin_N	LAMB1 LAMA1	5.01e-04	16	39	2	IPR008211
Domain	LAMININ_NTER	LAMB1 LAMA1	5.01e-04	16	39	2	PS51117
Domain	Laminin_N	LAMB1 LAMA1	5.01e-04	16	39	2	PF00055
Domain	LamNT	LAMB1 LAMA1	5.01e-04	16	39	2	SM00136
Domain	CTCK_1	VWF SLIT3	6.36e-04	18	39	2	PS01185
Domain	CT	VWF SLIT3	9.56e-04	22	39	2	SM00041
Domain	Protein_kinase_ATP_BS	PRKCA PRKCB PRKCE PRKCH INSR	1.09e-03	379	39	5	IPR017441
Domain	Cys_knot_C	VWF SLIT3	1.24e-03	25	39	2	IPR006207
Domain	CTCK_2	VWF SLIT3	1.24e-03	25	39	2	PS01225
Domain	EGF_LAM_2	LAMB1 LAMA1	1.78e-03	30	39	2	PS50027
Domain	EGF_LAM_1	LAMB1 LAMA1	1.78e-03	30	39	2	PS01248
Domain	EGF_1	LAMB1 ADAM28 SLIT3 LAMA1	1.92e-03	255	39	4	PS00022
Domain	LRRCT	CHAD SLIT3	2.03e-03	32	39	2	PF01463
Domain	EGF-like_CS	LAMB1 ADAM28 SLIT3 LAMA1	2.09e-03	261	39	4	IPR013032
Domain	EGF_2	LAMB1 ADAM28 SLIT3 LAMA1	2.21e-03	265	39	4	PS01186
Domain	-	SHPRH ZFYVE26 TRIM25 JADE3 ZFPL1	2.31e-03	449	39	5	3.30.40.10
Domain	Laminin_EGF	LAMB1 LAMA1	2.42e-03	35	39	2	PF00053
Domain	EGF_Lam	LAMB1 LAMA1	2.42e-03	35	39	2	SM00180
Domain	PROTEIN_KINASE_ATP	PRKCA PRKCB PRKCE PRKCH INSR	2.54e-03	459	39	5	PS00107
Domain	Znf_RING/FYVE/PHD	SHPRH ZFYVE26 TRIM25 JADE3 ZFPL1	2.54e-03	459	39	5	IPR013083
Domain	LAM_G_DOMAIN	SLIT3 LAMA1	2.85e-03	38	39	2	PS50025
Domain	Laminin_EGF	LAMB1 LAMA1	2.85e-03	38	39	2	IPR002049
Domain	ZF_RING_1	SHPRH NFXL1 TRIM25 ZFPL1	3.09e-03	291	39	4	PS00518
Domain	Laminin_G_2	SLIT3 LAMA1	3.15e-03	40	39	2	PF02210
Domain	Prot_kinase_dom	PRKCA PRKCB PRKCE PRKCH INSR	3.33e-03	489	39	5	IPR000719
Domain	ZF_RING_2	SHPRH NFXL1 TRIM25 ZFPL1	3.37e-03	298	39	4	PS50089
Domain	PROTEIN_KINASE_DOM	PRKCA PRKCB PRKCE PRKCH INSR	3.45e-03	493	39	5	PS50011
Domain	Znf_FYVE_PHD	SHPRH ZFYVE26 JADE3	3.55e-03	147	39	3	IPR011011
Domain	LamG	SLIT3 LAMA1	3.80e-03	44	39	2	SM00282
Domain	Znf_RING	SHPRH NFXL1 TRIM25 ZFPL1	4.63e-03	326	39	4	IPR001841
Domain	Kinase-like_dom	PRKCA PRKCB PRKCE PRKCH INSR	5.15e-03	542	39	5	IPR011009
Pathway	PID_NFAT_3PATHWAY	PRKCA PRKCB PRKCE PRKCH CREBBP	9.77e-08	53	31	5	M113
Pathway	WP_FOCAL_ADHESION	LAMB1 PRKCA PRKCB CHAD VWF ZYX LAMA1	1.98e-07	199	31	7	M39402
Pathway	KEGG_FOCAL_ADHESION	LAMB1 PRKCA PRKCB CHAD VWF ZYX LAMA1	1.98e-07	199	31	7	M7253
Pathway	PID_RAS_PATHWAY	PRKCA PRKCB PRKCE RASGRP4	5.04e-07	30	31	4	M269
Pathway	WP_KISSPEPTINKISSPEPTIN_RECEPTOR_SYSTEM_IN_THE_OVARY	PRKCA PRKCB PRKCE PRKCH	1.49e-06	39	31	4	M39905
Pathway	WP_HIPPO_SIGNALING_REGULATION	PRKCA PRKCB PRKCE PRKCH INSR	2.16e-06	98	31	5	M39830
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	PRKCA PRKCB PRKCE PRKCH CREBBP	2.50e-06	101	31	5	M39387
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	PRKCA PRKCB PRKCE PRKCH CREBBP	2.50e-06	101	31	5	MM15829
Pathway	BIOCARTA_KERATINOCYTE_PATHWAY	PRKCA PRKCB PRKCE PRKCH	2.93e-06	46	31	4	M19118
Pathway	BIOCARTA_KERATINOCYTE_PATHWAY	PRKCA PRKCB PRKCE PRKCH	2.93e-06	46	31	4	MM1428
Pathway	WP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION	PRKCA PRKCB PRKCE PRKCH	2.93e-06	46	31	4	M46450
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	PRKCA PRKCB PRKCE PRKCH	3.48e-06	48	31	4	M10775
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	PRKCA PRKCB PRKCE PRKCH PLA2G2C	4.75e-06	115	31	5	M9387
Pathway	PID_TXA2PATHWAY	PRKCA PRKCB PRKCE PRKCH	6.49e-06	56	31	4	M99
Pathway	WP_WNT_SIGNALING	PRKCA PRKCB PRKCE PRKCH	9.15e-06	61	31	4	MM15893
Pathway	PID_ENDOTHELIN_PATHWAY	PRKCA PRKCB PRKCE PRKCH	1.04e-05	63	31	4	M8
Pathway	WP_ONCOSTATIN_M_SIGNALING	PRKCA PRKCB PRKCE PRKCH	1.18e-05	65	31	4	M39562
Pathway	REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	PRKCA PRKCB PRKCE PRKCH VWF DAGLA	1.90e-05	261	31	6	M1077
Pathway	WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3	PRKCA PRKCB PRKCE PRKCH	2.09e-05	75	31	4	M39568
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	PRKCE PRKCH DAGLA	2.14e-05	25	31	3	MM14511
Pathway	KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY	PRKCA PRKCB PRKCE PLA2G2C	2.56e-05	79	31	4	M11816
Pathway	BIOCARTA_GH_PATHWAY	PRKCA PRKCB INSR	2.72e-05	27	31	3	M9043
Pathway	REACTOME_EFFECTS_OF_PIP2_HYDROLYSIS	PRKCE PRKCH DAGLA	2.72e-05	27	31	3	M12123
Pathway	PID_IL8_CXCR1_PATHWAY	PRKCA PRKCB PRKCE	3.04e-05	28	31	3	M252
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMB1 CHAD VWF LAMA1	3.26e-05	84	31	4	M7098
Pathway	WP_G_PROTEIN_SIGNALING_PATHWAYS	PRKCA PRKCB PRKCE PRKCH	4.28e-05	90	31	4	MM15882
Pathway	WP_G_PROTEIN_SIGNALING	PRKCA PRKCB PRKCE PRKCH	4.47e-05	91	31	4	M39426
Pathway	WP_RAS_SIGNALING	PRKCA PRKCB RASGRP4 PLA2G2C INSR	4.63e-05	184	31	5	M39764
Pathway	BIOCARTA_ION_PATHWAY	PRKCA PRKCB	4.66e-05	5	31	2	MM1574
Pathway	BIOCARTA_PLCD_PATHWAY	PRKCA PRKCB	4.66e-05	5	31	2	MM1587
Pathway	BIOCARTA_ION_PATHWAY	PRKCA PRKCB	4.66e-05	5	31	2	M22059
Pathway	BIOCARTA_PLCD_PATHWAY	PRKCA PRKCB	4.66e-05	5	31	2	M22080
Pathway	REACTOME_DISINHIBITION_OF_SNARE_FORMATION	PRKCA PRKCB	4.66e-05	5	31	2	M26920
Pathway	WP_FOCAL_ADHESION	LAMB1 CHAD VWF ZYX LAMA1	5.00e-05	187	31	5	MM15913
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMB1 PRKCA LAMA1	5.02e-05	33	31	3	M39503
Pathway	BIOCARTA_GH_PATHWAY	PRKCA PRKCB INSR	5.02e-05	33	31	3	MM1404
Pathway	WP_PI3KAKT_SIGNALING	LAMB1 PRKCA CHAD VWF INSR LAMA1	8.19e-05	339	31	6	M39736
Pathway	BIOCARTA_ERBB4_PATHWAY	PRKCA PRKCB	9.76e-05	7	31	2	MM1563
Pathway	BIOCARTA_PKC_PATHWAY	PRKCA PRKCB	9.76e-05	7	31	2	MM1572
Pathway	BIOCARTA_ERBB4_PATHWAY	PRKCA PRKCB	9.76e-05	7	31	2	M22043
Pathway	BIOCARTA_PKC_PATHWAY	PRKCA PRKCB	9.76e-05	7	31	2	M22057
Pathway	REACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_MYELOID_CELLS	PRKCB CREBBP	9.76e-05	7	31	2	M27799
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	HRH1 PRKCA PRKCE PRKCH DAGLA	1.01e-04	217	31	5	M18437
Pathway	KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION	PRKCA PRKCB INSR	1.04e-04	42	31	3	M16473
Pathway	PID_THROMBIN_PAR1_PATHWAY	PRKCA PRKCB ZYX	1.12e-04	43	31	3	M238
Pathway	WP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES	PRKCA PRKCB PRKCE PRKCH	1.23e-04	118	31	4	M39852
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US27_TO_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	1.30e-04	8	31	2	M47555
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_PLCG_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	1.30e-04	8	31	2	M47479
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMB1 PRKCA LAMA1	1.37e-04	46	31	3	M239
Pathway	BIOCARTA_PLC_PATHWAY	PRKCA PRKCB	1.67e-04	9	31	2	M22029
Pathway	BIOCARTA_PLC_PATHWAY	PRKCA PRKCB	1.67e-04	9	31	2	MM1551
Pathway	KEGG_TIGHT_JUNCTION	PRKCA PRKCB PRKCE PRKCH	1.90e-04	132	31	4	M11355
Pathway	BIOCARTA_PPARA_PATHWAY	PRKCA PRKCB CREBBP	1.98e-04	52	31	3	M2404
Pathway	BIOCARTA_SRCRPTP_PATHWAY	PRKCA PRKCB	2.08e-04	10	31	2	MM1341
Pathway	BIOCARTA_AGPCR_PATHWAY	PRKCA PRKCB	2.08e-04	10	31	2	MM1352
Pathway	KEGG_MEDICUS_REFERENCE_TAC3_TACR3_PLC_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	2.08e-04	10	31	2	M47644
Pathway	PID_CD8_TCR_PATHWAY	PRKCA PRKCB PRKCE	2.09e-04	53	31	3	M88
Pathway	REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	PRKCB PRKCE PRKCH VWF DAGLA	2.23e-04	257	31	5	MM15454
Pathway	BIOCARTA_CBL_PATHWAY	PRKCA PRKCB	2.54e-04	11	31	2	MM1360
Pathway	KEGG_MEDICUS_REFERENCE_KISS1_KISS1R_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	2.54e-04	11	31	2	M47637
Pathway	BIOCARTA_SRCRPTP_PATHWAY	PRKCA PRKCB	2.54e-04	11	31	2	M10994
Pathway	BIOCARTA_MYOSIN_PATHWAY	PRKCA PRKCB	2.54e-04	11	31	2	M7014
Pathway	BIOCARTA_AGPCR_PATHWAY	PRKCA PRKCB	2.54e-04	11	31	2	M19829
Pathway	PID_INTEGRIN4_PATHWAY	LAMB1 LAMA1	2.54e-04	11	31	2	M158
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	PRKCA PRKCB PRKCE PRKCH	2.87e-04	147	31	4	MM15854
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	LAMB1 PRKCA LAMA1	2.88e-04	59	31	3	M27218
Pathway	BIOCARTA_PRION_PATHWAY	LAMB1 LAMA1	3.05e-04	12	31	2	M22020
Pathway	KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	3.05e-04	12	31	2	M47597
Pathway	KEGG_MEDICUS_REFERENCE_TRH_TRHR_PLCB_PKC_SIGNALING_PATHWAY	PRKCA PRKCB	3.05e-04	12	31	2	M47649
Pathway	KEGG_MEDICUS_REFERENCE_TSH_DUOX2_TG_SIGNALING_PATHWAY	PRKCA PRKCB	3.05e-04	12	31	2	M47628
Pathway	BIOCARTA_CBL_PATHWAY	PRKCA PRKCB	3.05e-04	12	31	2	M16973
Pathway	WP_CALCIUM_REGULATION_IN_CARDIAC_CELLS	PRKCA PRKCB PRKCE PRKCH	3.18e-04	151	31	4	M39329
Pathway	WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS	PRKCA PRKCB PRKCE PRKCH	3.43e-04	154	31	4	MM15974
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	PRKCA PRKCB	3.60e-04	13	31	2	M47656
Pathway	WP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS	PRKCA PRKCB PRKCE PRKCH	3.60e-04	156	31	4	M39475
Pathway	PID_TCR_PATHWAY	PRKCA PRKCB PRKCE	3.66e-04	64	31	3	M34
Pathway	PID_CD8_TCR_DOWNSTREAM_PATHWAY	PRKCA PRKCB PRKCE	3.84e-04	65	31	3	M272
Pathway	WP_INSULIN_SIGNALING	PRKCA PRKCB PRKCH INSR	3.96e-04	160	31	4	MM15956
Pathway	WP_INSULIN_SIGNALING	PRKCA PRKCB PRKCH INSR	3.96e-04	160	31	4	M39482
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	LAMB1 PRKCA LAMA1	4.01e-04	66	31	3	MM15925
Pathway	WP_AGERAGE_PATHWAY	PRKCA PRKCB INSR	4.01e-04	66	31	3	M39420
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	4.19e-04	14	31	2	M47383
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	4.19e-04	14	31	2	M47384
Pathway	PID_TCR_RAS_PATHWAY	PRKCA PRKCB	4.19e-04	14	31	2	M134
Pathway	WP_6Q16_COPY_NUMBER_VARIATION	LEPR INSR	4.19e-04	14	31	2	M48100
Pathway	BIOCARTA_TRKA_PATHWAY	PRKCA PRKCB	4.19e-04	14	31	2	M9134
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING	LAMB1 CHAD VWF INSR LAMA1	4.69e-04	302	31	5	M39719
Pathway	KEGG_LONG_TERM_DEPRESSION	PRKCA PRKCB PLA2G2C	4.77e-04	70	31	3	M8232
Pathway	KEGG_LONG_TERM_POTENTIATION	PRKCA PRKCB CREBBP	4.77e-04	70	31	3	M3115
Pathway	BIOCARTA_CDMAC_PATHWAY	PRKCA PRKCB	4.83e-04	15	31	2	MM1358
Pathway	BIOCARTA_TRKA_PATHWAY	PRKCA PRKCB	4.83e-04	15	31	2	MM1523
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY	PRKCA PRKCB	4.83e-04	15	31	2	M47382
Pathway	REACTOME_DEPOLYMERIZATION_OF_THE_NUCLEAR_LAMINA	PRKCA PRKCB	4.83e-04	15	31	2	M27360
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	PRKCA PRKCB	4.83e-04	15	31	2	M27413
Pathway	REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY	TRIM25 CREBBP	4.83e-04	15	31	2	M953
Pathway	BIOCARTA_MEF2D_PATHWAY	PRKCA PRKCB	5.51e-04	16	31	2	MM1483
Pathway	BIOCARTA_SPPA_PATHWAY	PRKCA PRKCB	5.51e-04	16	31	2	M8731
Pathway	BIOCARTA_CDMAC_PATHWAY	PRKCA PRKCB	5.51e-04	16	31	2	M4388
Pathway	REACTOME_HEMOSTASIS	PRKCA PRKCB PRKCE PRKCH VWF DOCK8 DAGLA	5.56e-04	679	31	7	M8395
Pathway	KEGG_VEGF_SIGNALING_PATHWAY	PRKCA PRKCB PLA2G2C	6.07e-04	76	31	3	M1749
Pubmed	Protein kinase C isoform expression and activity in the mouse heart.	PRKCA PRKCB PRKCE PRKCH	2.25e-11	6	40	4	11668067
Pubmed	Translocation of diacylglycerol kinase theta from cytosol to plasma membrane in response to activation of G protein-coupled receptors and protein kinase C.	PRKCA PRKCB PRKCE PRKCH	2.25e-11	6	40	4	15632189
Pubmed	The Protein-tyrosine-phosphatase SHP2 is phosphorylated on serine residues 576 and 591 by protein kinase C isoforms alpha, beta 1, beta 2, and eta.	PRKCA PRKCB PRKCH INSR	5.23e-11	7	40	4	11781100
Pubmed	Distribution of the extended family of protein kinase C isoenzymes in fetal organs of mice: an immunohistochemical study.	PRKCA PRKCB PRKCE PRKCH	1.05e-10	8	40	4	7606770
Pubmed	aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb.	PRKCA PRKCB PRKCE PRKCH	1.88e-10	9	40	4	17203073
Pubmed	Inhibition of protein kinase C by a synthetic peptide corresponding to cytoplasmic domain residues 828-848 of the human immunodeficiency virus type 1 envelope glycoprotein.	PRKCA PRKCB PRKCE PRKCH	1.88e-10	9	40	4	7850771
Pubmed	Human immunodeficiency virus-1 recombinant gp120 induces changes in protein kinase C isozymes--a preliminary report.	PRKCA PRKCB PRKCE PRKCH	1.88e-10	9	40	4	8206685
Pubmed	Regulation of HIV-1 gag protein subcellular targeting by protein kinase C.	PRKCA PRKCB PRKCE PRKCH	1.88e-10	9	40	4	7876252
Pubmed	Cypher, a striated muscle-restricted PDZ and LIM domain-containing protein, binds to alpha-actinin-2 and protein kinase C.	PRKCA PRKCB PRKCE LDB3	1.88e-10	9	40	4	10391924
Pubmed	Phosphorylation of HIV-1 gag proteins by protein kinase C.	PRKCA PRKCB PRKCE PRKCH	1.88e-10	9	40	4	8473314
Pubmed	Phosphorylation of the cytoplasmic domain of the integrin CD18 chain by protein kinase C isoforms in leukocytes.	PRKCA PRKCB PRKCE PRKCH	1.88e-10	9	40	4	11700305
Pubmed	The phorbol ester TPA strongly inhibits HIV-1-induced syncytia formation but enhances virus production: possible involvement of protein kinase C pathway.	PRKCA PRKCB PRKCE PRKCH	3.13e-10	10	40	4	1970444
Pubmed	Human immunodeficiency virus induces phosphorylation of its cell surface receptor.	PRKCA PRKCB PRKCE PRKCH	3.13e-10	10	40	4	3259291
Pubmed	Effect of serine and tyrosine phosphorylation on retroviral proteinase substrates.	PRKCA PRKCB PRKCE PRKCH	3.13e-10	10	40	4	10491200
Pubmed	Inhibition of protein kinase C and anti-CD3-induced Ca2+ influx in Jurkat T cells by a synthetic peptide with sequence identity to HIV-1 gp41.	PRKCA PRKCB PRKCE PRKCH	3.13e-10	10	40	4	2139676
Pubmed	Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol.	PRKCA PRKCB PRKCE PRKCH	4.92e-10	11	40	4	14613966
Pubmed	IL-16- and other CD4 ligand-induced migration is dependent upon protein kinase C.	PRKCA PRKCB PRKCE PRKCH	4.92e-10	11	40	4	8599832
Pubmed	Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.	PRKCA PRKCB PRKCE PRKCH	4.92e-10	11	40	4	2182321
Pubmed	In vitro phosphorylation of human immunodeficiency virus type 1 Tat protein by protein kinase C: evidence for the phosphorylation of amino acid residue serine-46.	PRKCA PRKCB PRKCE PRKCH	4.92e-10	11	40	4	8914829
Pubmed	Expression profile of protein kinase C isozymes in preimplantation mouse development.	PRKCA PRKCB PRKCE PRKCH	4.92e-10	11	40	4	16183862
Pubmed	Involvement of protein kinase C in HIV-1 gp120-induced apoptosis in primary endothelium.	PRKCA PRKCB PRKCE PRKCH	7.37e-10	12	40	4	11141237
Pubmed	HIV-1 Tat and AIDS-associated cancer: targeting the cellular anti-cancer barrier?	PRKCA PRKCB PRKCE PRKCH	7.37e-10	12	40	4	18577246
Pubmed	c-FLIPL regulates PKC via AP-2 to inhibit Bax-mediated apoptosis induced by HIV-1 gp120 in Jurkat cells.	PRKCA PRKCB PRKCE PRKCH	7.37e-10	12	40	4	19363595
Pubmed	HIV-1 Tat protein induces interleukin-10 in human peripheral blood monocytes: involvement of protein kinase C-betaII and -delta.	PRKCA PRKCB PRKCE PRKCH	7.37e-10	12	40	4	11919157
Pubmed	HIV-1 reverse transcriptase is phosphorylated in vitro and in a cellular system.	PRKCA PRKCB PRKCE PRKCH	1.06e-09	13	40	4	10641798
Pubmed	The inhibition of differentiation caused by TGFbeta in fetal myoblasts is dependent upon selective expression of PKCtheta: a possible molecular basis for myoblast diversification during limb histogenesis.	PRKCA PRKCB PRKCE PRKCH	1.06e-09	13	40	4	8948582
Pubmed	EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland.	PRKCA PRKCB PRKCE PRKCH	1.06e-09	13	40	4	12761849
Pubmed	Dual inhibition of classical protein kinase C-α and protein kinase C-β isoforms protects against experimental murine diabetic nephropathy.	PRKCA PRKCB LEPR	1.41e-09	3	40	3	23434935
Pubmed	Role of protein kinase C in selective inhibition of mouse retinal neurites during contacts with chondroitin sulfates.	PRKCA PRKCB PRKCE	1.41e-09	3	40	3	18313852
Pubmed	PKC activation in Niemann pick C1 cells restores subcellular cholesterol transport.	PRKCA PRKCB PRKCE	1.41e-09	3	40	3	23977398
Pubmed	HIV-1 envelope glycoproteins induce activation of activated protein-1 in CD4+ T cells.	PRKCA PRKCB PRKCE PRKCH	1.49e-09	14	40	4	7642615
Pubmed	G proteins Gαi1/3 are critical targets for Bordetella pertussis toxin-induced vasoactive amine sensitization.	HRH1 PRKCA PRKCB PRKCE	2.03e-09	15	40	4	24478091
Pubmed	Extracellular human immunodeficiency virus type 1 Tat protein is associated with an increase in both NF-kappa B binding and protein kinase C activity in primary human astrocytes.	PRKCA PRKCB PRKCE PRKCH	2.03e-09	15	40	4	8627654
Pubmed	HIV envelope gp120 activates human arterial smooth muscle cells.	PRKCA PRKCB PRKCE PRKCH	2.03e-09	15	40	4	11504923
Pubmed	A synthetic peptide with sequence identity to the transmembrane protein GP41 of HIV-1 inhibits distinct lymphocyte activation pathways dependent on protein kinase C and intracellular calcium influx.	PRKCA PRKCB PRKCE PRKCH	2.70e-09	16	40	4	1832084
Pubmed	[HIV-1 Tat protein induces IL-10 production by human monocytes: implications of the PKC and calcium pathway].	PRKCA PRKCB PRKCE PRKCH	2.70e-09	16	40	4	11833470
Pubmed	Inhibition of TRPC6 by protein kinase C isoforms in cultured human podocytes.	PRKCA PRKCB PRKCH	5.63e-09	4	40	3	26404773
Pubmed	Effects of the antiandrogen flutamide on the expression of protein kinase C isoenzymes in LNCaP and PC3 human prostate cancer cells.	PRKCA PRKCB PRKCE	5.63e-09	4	40	3	15499829
Pubmed	Differentiation of nonbeating embryonic stem cells into beating cardiomyocytes is dependent on downregulation of PKC beta and zeta in concert with upregulation of PKC epsilon.	PRKCB PRKCE PRKCH	5.63e-09	4	40	3	12648500
Pubmed	Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway.	PRKCA PRKCB PRKCE PRKCH	7.17e-09	20	40	4	11044099
Pubmed	Extracellular HIV-1 Tat protein induces a rapid and selective activation of protein kinase C (PKC)-alpha, and -epsilon and -zeta isoforms in PC12 cells.	PRKCA PRKCB PRKCE PRKCH	8.85e-09	21	40	4	9446795
Pubmed	The human immunodeficiency virus coat protein gp120 promotes forward trafficking and surface clustering of NMDA receptors in membrane microdomains.	PRKCA PRKCB PRKCE PRKCH	8.85e-09	21	40	4	22114277
Pubmed	Human immunodeficiency virus Tat protein induces interleukin 6 mRNA expression in human brain endothelial cells via protein kinase C- and cAMP-dependent protein kinase pathways.	PRKCA PRKCB PRKCE PRKCH	8.85e-09	21	40	4	9671211
Pubmed	HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.	PRKCA PRKCB PRKCE PRKCH	1.08e-08	22	40	4	11154208
Pubmed	The Nef protein of human immunodeficiency virus type 1 enhances serine phosphorylation of the viral matrix.	PRKCA PRKCB PRKCE PRKCH	1.08e-08	22	40	4	9151826
Pubmed	A new member of the third class in the protein kinase C family, PKC lambda, expressed dominantly in an undifferentiated mouse embryonal carcinoma cell line and also in many tissues and cells.	PRKCA PRKCB PRKCE	1.41e-08	5	40	3	7513693
Pubmed	IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes.	PRKCA PRKCB PRKCE	1.41e-08	5	40	3	15488737
Pubmed	Cell type-specific expression of the genes for the protein kinase C family: down regulation of mRNAs for PKC alpha and nPKC epsilon upon in vitro differentiation of a mouse neuroblastoma cell line neuro 2a.	PRKCA PRKCB PRKCE	1.41e-08	5	40	3	2590242
Pubmed	Protein kinase C activity regulates the onset of anaphase I in mouse oocytes.	PRKCA PRKCB PRKCE	1.41e-08	5	40	3	15229137
Pubmed	High-molecular weight hyaluronan reduced renal PKC activation in genetically diabetic mice.	PRKCB PRKCE LEPR	1.41e-08	5	40	3	20713153
Pubmed	Release of calcium from inositol 1,4,5-trisphosphate receptor-regulated stores by HIV-1 Tat regulates TNF-alpha production in human macrophages.	PRKCA PRKCB PRKCE PRKCH	1.57e-08	24	40	4	10843712
Pubmed	Signalling crosstalk in FGF2-mediated protection of endothelial cells from HIV-gp120.	PRKCA PRKCB PRKCE PRKCH	1.86e-08	25	40	4	15689238
Pubmed	Role of phosphorylation in the nuclear biology of HIV-1.	PRKCA PRKCB PRKCE PRKCH	2.58e-08	27	40	4	21651489
Pubmed	Mechanism of HIV-1-TAT induction of interleukin-1beta from human monocytes: Involvement of the phospholipase C/protein kinase C signaling cascade.	PRKCA PRKCB PRKCE PRKCH	2.58e-08	27	40	4	20336759
Pubmed	Differential expression of protein kinase C isoforms in coronary arteries of diabetic mice lacking the G-protein Gα11.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	21190563
Pubmed	Regulation of the tumour suppressor Fbw7α by PKC-dependent phosphorylation and cancer-associated mutations.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	20815813
Pubmed	Localization of protein kinase C isoforms in the optic pathway of mouse embryos and their role in axon routing at the optic chiasm.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	24863469
Pubmed	Diacylglycerol kinase θ counteracts protein kinase C-mediated inactivation of the EGF receptor.	PRKCA PRKCE PRKCH	2.81e-08	6	40	3	22732145
Pubmed	Expression and activity of protein kinase C isoenzymes during normal and abnormal murine palate development.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	10879655
Pubmed	The use of fluorescent phorbol esters in studies of protein kinase C-membrane interactions.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	12093536
Pubmed	An immunohistochemical study of protein kinase C distribution in fetal mouse vertebral column.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	7985811
Pubmed	Platelet P-selectin expression: requirement for protein kinase C, but not protein tyrosine kinase or phosphoinositide 3-kinase.	PRKCA PRKCE PRKCH	2.81e-08	6	40	3	12783114
Pubmed	PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5.	PRKCA PRKCB PRKCE	2.81e-08	6	40	3	30485813
Pubmed	Protein kinase C isoforms differentially phosphorylate human choline acetyltransferase regulating its catalytic activity.	PRKCA PRKCB PRKCE	4.92e-08	7	40	3	15381704
Pubmed	The myristoylated alanine-rich C-kinase substrate (MARCKS) is sequentially phosphorylated by conventional, novel and atypical isotypes of protein kinase C.	PRKCA PRKCB PRKCE	4.92e-08	7	40	3	7588787
Pubmed	Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells.	PRKCA PRKCB PRKCE	4.92e-08	7	40	3	12618484
Pubmed	Oxygen deprivation triggers upregulation of early growth response-1 by the receptor for advanced glycation end products.	PRKCA PRKCB PRKCE	4.92e-08	7	40	3	18323529
Pubmed	Conventional protein kinase C-α (PKC-α) and PKC-β negatively regulate RIG-I antiviral signal transduction.	PRKCA PRKCB TRIM25	4.92e-08	7	40	3	22114345
Pubmed	Developmental expression of MARCKS and protein kinase C in mice in relation to the exencephaly resulting from MARCKS deficiency.	PRKCA PRKCB PRKCE	7.86e-08	8	40	3	8922669
Pubmed	PC phosphorylation increases the ability of AFAP-110 to cross-link actin filaments.	PRKCA PRKCB PRKCE	7.86e-08	8	40	3	12134071
Pubmed	Protein-protein interaction of zinc finger LIM domains with protein kinase C.	PRKCA PRKCB PRKCE	7.86e-08	8	40	3	8940095
Pubmed	Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations.	PRKCA PRKCB PRKCE	7.86e-08	8	40	3	15894802
Pubmed	Ca2+/calmodulin-dependent protein kinase II regulates Tiam1 by reversible protein phosphorylation.	PRKCA PRKCB PRKCE	7.86e-08	8	40	3	10212259
Pubmed	Signaling pathways triggered by HIV-1 Tat in human monocytes to induce TNF-alpha.	PRKCA PRKCB PRKCE PRKCH	1.08e-07	38	40	4	12482669
Pubmed	Btk regulation in human and mouse B cells via protein kinase C phosphorylation of IBtkγ.	PRKCA PRKCB PRKCE	1.68e-07	10	40	3	21482705
Pubmed	Convergence of multiple signaling cascades at glycogen synthase kinase 3: Edg receptor-mediated phosphorylation and inactivation by lysophosphatidic acid through a protein kinase C-dependent intracellular pathway.	PRKCA PRKCB PRKCH	1.68e-07	10	40	3	11884598
Pubmed	Phosphorylation of tau is regulated by PKN.	PRKCA PRKCB PRKCE	2.31e-07	11	40	3	11104762
Pubmed	Association of CPI-17 with protein kinase C and casein kinase I.	PRKCA PRKCE PRKCH	6.35e-07	15	40	3	15003508
Pubmed	Distinct and complementary roles for α and β isoenzymes of PKC in mediating vasoconstrictor responses to acutely elevated glucose.	PRKCA PRKCB	1.29e-06	2	40	2	26660275
Pubmed	Insulin inhibits phagocytosis in normal human neutrophils via PKCalpha/beta-dependent priming of F-actin assembly.	PRKCA PRKCB	1.29e-06	2	40	2	16673150
Pubmed	Heterogeneity of cellular proliferation within transitional cell carcinoma: correlation of protein kinase C alpha/betaI expression and activity.	PRKCA PRKCB	1.29e-06	2	40	2	16517978
Pubmed	Monoclonal anti-mouse laminin antibodies: AL-1 reacts with laminin alpha1 chain, AL-2 with laminin beta1 chain, and AL-4 with the coiled-coil domain of laminin beta1 chain.	LAMB1 LAMA1	1.29e-06	2	40	2	16631359
Pubmed	Mechanism of lipid induced insulin resistance: activated PKCε is a key regulator.	PRKCE LEPR	1.29e-06	2	40	2	21236337
Pubmed	Effects of azidothymidine on protein kinase C activity and expression in erythroleukemic cell K562 and acute lymphoblastic leukemia cell HSB-2.	PRKCA PRKCB	1.29e-06	2	40	2	25693686
Pubmed	Protein kinase C alpha and epsilon phosphorylation of troponin and myosin binding protein C reduce Ca2+ sensitivity in human myocardium.	PRKCA PRKCE	1.29e-06	2	40	2	19655190
Pubmed	Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held.	PRKCA PRKCB	1.29e-06	2	40	2	21658591
Pubmed	Curcumin Inhibits Protein Kinase Cα Activity by Binding to Its C1 Domain.	PRKCA PRKCE	1.29e-06	2	40	2	27776404
Pubmed	Maternal obesity modulates sexually dimorphic epigenetic regulation and expression of leptin receptor in offspring hippocampus.	LEPR INSR	1.29e-06	2	40	2	32173454
Pubmed	HIV-1 Nef alters the expression of betaII and epsilon isoforms of protein kinase C and the activation of the long terminal repeat promoter in human astrocytoma cells.	PRKCB PRKCE	1.29e-06	2	40	2	10417813
Pubmed	Opposing effects of PKCalpha and PKCepsilon on basolateral membrane dynamics in intestinal epithelia.	PRKCA PRKCE	1.29e-06	2	40	2	12372816
Pubmed	Cross down-regulation of leptin and insulin receptor expression and signalling in a human neuronal cell line.	LEPR INSR	1.29e-06	2	40	2	15715521
Pubmed	Reactivation of fetal splicing programs in diabetic hearts is mediated by protein kinase C signaling.	PRKCA PRKCB	1.29e-06	2	40	2	24151077
Pubmed	Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity.	PRKCA PRKCB	1.29e-06	2	40	2	29307535
Pubmed	Genes encoding catalytic subunits of protein kinase A and risk of spina bifida.	PRKCA PRKCB	1.29e-06	2	40	2	16080189
Pubmed	Receptor-specific regulation of atrial GIRK channel activity by different Ca2+-dependent PKC isoforms.	PRKCA PRKCB	1.29e-06	2	40	2	31525436
Pubmed	Insulin and leptin receptors as possible new candidates for endocrine control in normal and disturbed human pregnancy.	LEPR INSR	1.29e-06	2	40	2	19246519
Pubmed	Protein kinase C modulates agonist-sensitive release of Ca2+ from internal stores in HEK293 cells overexpressing the calcium sensing receptor.	PRKCA PRKCE	1.29e-06	2	40	2	15572354
Pubmed	Form and function: the laminin family of heterotrimers.	LAMB1 LAMA1	1.29e-06	2	40	2	10842354
Pubmed	Interaction of the human insulin receptor tyrosine kinase from the baculovirus expression system with protein kinase C in a cell-free system.	PRKCA INSR	1.29e-06	2	40	2	8463287
Pubmed	Unravelling the different functions of protein kinase C isoforms in platelets.	PRKCA PRKCB	1.29e-06	2	40	2	21596041
Interaction	LDB3 interactions	PRKCA PRKCB PRKCE LDB3	1.97e-07	29	36	4	int:LDB3
Interaction	TIAM1 interactions	PRKCA PRKCB PRKCE CAMSAP2 CREBBP ZFPL1	1.56e-06	205	36	6	int:TIAM1
Interaction	ITGB2 interactions	PRKCA PRKCB PRKCE PRKCH UBR4	3.58e-06	132	36	5	int:ITGB2
Interaction	PRKCD interactions	PRKCA PRKCB PRKCE LDB3 CREBBP INSR	3.69e-06	238	36	6	int:PRKCD
Interaction	AFAP1 interactions	PRKCA PRKCB PRKCE TRIM25	4.16e-06	61	36	4	int:AFAP1
Interaction	CHAT interactions	PRKCA PRKCB PRKCE	4.19e-06	18	36	3	int:CHAT
Interaction	PPP1R14A interactions	PRKCA PRKCE PRKCH	7.88e-06	22	36	3	int:PPP1R14A
Interaction	PRKCE interactions	PRKCA PRKCB PRKCE PRKCH LDB3	1.34e-05	173	36	5	int:PRKCE
Interaction	TIAM2 interactions	PRKCA PRKCB PRKCE	1.85e-05	29	36	3	int:TIAM2
Interaction	IFNAR2 interactions	PRKCB TRIM25 CREBBP	3.02e-05	34	36	3	int:IFNAR2
Interaction	PRKCH interactions	PRKCA PRKCE PRKCH	3.29e-05	35	36	3	int:PRKCH
Interaction	PTPN11 interactions	PRKCA PRKCB PRKCH TRIM25 LEPR INSR	4.36e-05	368	36	6	int:PTPN11
Interaction	CISH interactions	PRKCA PRKCB LEPR	4.94e-05	40	36	3	int:CISH
Interaction	AKAP13 interactions	PRKCA PRKCH TRIM25 ZYX	5.32e-05	116	36	4	int:AKAP13
Interaction	NUMB interactions	PRKCA PRKCB PRKCE PRKCH ZFPL1	5.46e-05	232	36	5	int:NUMB
Interaction	GRM5 interactions	PRKCA PRKCB PRKCE	6.15e-05	43	36	3	int:GRM5
Interaction	PRKCG interactions	PRKCA PRKCB PRKCE LDB3	6.28e-05	121	36	4	int:PRKCG
Interaction	HIPK3 interactions	TRIM25 CREBBP ZYX	6.59e-05	44	36	3	int:HIPK3
Interaction	ITGB1 interactions	PRKCA PRKCE ZFPL1 UBR4 INSR LAMA1	6.93e-05	400	36	6	int:ITGB1
Interaction	IBTK interactions	PRKCA PRKCB PRKCE TRIM25	7.35e-05	126	36	4	int:IBTK
Interaction	PRKCA interactions	PRKCA PRKCB PRKCE PRKCH LDB3 INSR	7.73e-05	408	36	6	int:PRKCA
Interaction	TAFA2 interactions	TRIM25 LEPR INSR	8.04e-05	47	36	3	int:TAFA2
Interaction	MARK2 interactions	PRKCE CAMSAP2 CREBBP ZFPL1 INSR	1.20e-04	274	36	5	int:MARK2
Interaction	NIBAN2 interactions	TRIM25 ZYX ZFPL1 INSR	1.20e-04	143	36	4	int:NIBAN2
Interaction	GNA12 interactions	PRKCA PRKCB PRKCE	1.36e-04	56	36	3	int:GNA12
Interaction	H3C1 interactions	SHPRH PRKCA PRKCB SMYD5 PRR14L CREBBP UBR4 CDC45	1.53e-04	901	36	8	int:H3C1
Interaction	AKAP12 interactions	PRKCA PRKCB PRKCE ZFPL1	1.68e-04	156	36	4	int:AKAP12
Interaction	PFKFB2 interactions	PRKCA TRIM25 DOCK8	1.84e-04	62	36	3	int:PFKFB2
Interaction	ACHE interactions	LAMB1 LAMA1	2.02e-04	12	36	2	int:ACHE
Interaction	RBCK1 interactions	PRKCA PRKCB TRIM25 CREBBP	2.66e-04	176	36	4	int:RBCK1
Interaction	HSP90AA1 interactions	PRKCA PRKCB PRKCE PRKCH PRR14L TRIM25 CREBBP RHOBTB2 UBR4	2.92e-04	1263	36	9	int:HSP90AA1
Interaction	PRKD1 interactions	PRKCE PRKCH ZYX UBR4	3.15e-04	184	36	4	int:PRKD1
Interaction	TMEM53 interactions	PRKCA TRIM25	3.21e-04	15	36	2	int:TMEM53
Interaction	SLC43A2 interactions	HRH1 TRIM25	3.21e-04	15	36	2	int:SLC43A2
Interaction	IGFL3 interactions	LAMB1 INSR LAMA1	3.24e-04	75	36	3	int:IGFL3
Interaction	TRAPPC3 interactions	TRIM25 INSR CDC45	3.36e-04	76	36	3	int:TRAPPC3
Interaction	JADE1 interactions	TRIM25 JADE3 CREBBP	3.50e-04	77	36	3	int:JADE1
Interaction	EGLN3 interactions	NFXL1 PRR14L TRIM25 ANKRD50 CAMSAP2 CREBBP ZFPL1 UBR4 CDC45	3.53e-04	1296	36	9	int:EGLN3
Interaction	RGS2 interactions	PRKCA PRKCB ZYX	3.91e-04	80	36	3	int:RGS2
Interaction	RPS6KA2 interactions	PRKCA PRKCE TRIM25 CREBBP	4.01e-04	196	36	4	int:RPS6KA2
Interaction	CD96 interactions	LAMB1 UBR4	4.15e-04	17	36	2	int:CD96
GeneFamily	C2 domain containing protein kinases	PRKCA PRKCB PRKCE PRKCH	1.47e-09	10	31	4	835
GeneFamily	LIM domain containing	LDB3 NRAP ZYX	1.39e-04	59	31	3	1218
GeneFamily	Laminin subunits	LAMB1 LAMA1	1.86e-04	12	31	2	626
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	PRKCA PRR14L DOCK8 CREBBP RHOBTB2	7.82e-06	180	40	5	M8239
Coexpression	GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN	PRKCA PRKCB PRR14L TRIM25 CREBBP	1.27e-05	199	40	5	M6987
Coexpression	NABA_CORE_MATRISOME	LAMB1 CHAD VWF SLIT3 LAMA1	5.48e-05	270	40	5	MM17057
Coexpression	NABA_CORE_MATRISOME	LAMB1 CHAD VWF SLIT3 LAMA1	5.97e-05	275	40	5	M5884
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 PRKCH VWF LEPR INSR	8.45e-07	195	40	5	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 CHAD RASGRP4 ZYX	1.24e-05	159	40	4	3bab00f8fb7d9232538e50f83dd0fd70ddd16819
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 CHAD RASGRP4 ZYX	1.27e-05	160	40	4	5bec867def73fa8531f8dad611679f4b44f573bd
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	PRKCB JADE3 DOCK8 ADAM28	1.54e-05	168	40	4	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NRAP INSR LAMA1	1.58e-05	169	40	4	8dba7546adc6b1345933eec81fc77fc9611fae60
ToppCell	facs-Lung-Endomucin-24m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF NRAP INSR LAMA1	1.58e-05	169	40	4	d2862a7ddee6d7a65d84ef9d0800ba6f4690973f
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRR14L VWF ZYX SLC36A2	1.62e-05	170	40	4	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	3'_v3-Lung-Lymphocytic_B-Memory_B_cells\|Lung / Manually curated celltypes from each tissue	PRKCB CHAD JADE3 ADAM28	1.65e-05	171	40	4	9ecef653f6916572bf5fbee5aea6c577d04e96ba
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 ZYX SLC36A2 SLIT3	1.77e-05	174	40	4	3c47d069bd836599a8d40eae485c23d4d3487517
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRKCB RASGRP4 DOCK8 ADAM28	1.85e-05	176	40	4	926ed37e636fe4dd3a18731cea15761f0c2c285a
ToppCell	390C-Endothelial_cells-Endothelial-E-\|390C / Donor, Lineage, Cell class and subclass (all cells)	HRH1 PRKCE VWF LEPR	1.94e-05	178	40	4	804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell	390C-Endothelial_cells-Endothelial-E\|390C / Donor, Lineage, Cell class and subclass (all cells)	HRH1 PRKCE VWF LEPR	1.94e-05	178	40	4	ad6dc4a375664c919bd48c35c48a561fc5a7de8c
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.07e-05	181	40	4	091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.11e-05	182	40	4	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	P28-Mesenchymal\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.11e-05	182	40	4	69f9d44694fe4f55a971ae0ac5dc3e7448ee78f3
ToppCell	3'_v3-blood-Lymphocytic_B-Memory_B_cells\|blood / Manually curated celltypes from each tissue	CHAD JADE3 ADAM28 RHOBTB2	2.16e-05	183	40	4	e3a418b745d7f040adf47be9e1043b945cae47ed
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PRKCH VWF ANKRD50 CDC45	2.21e-05	184	40	4	688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell	P28-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.21e-05	184	40	4	924400f47e6b2cdf7b0d538df75857935cf0209b
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.25e-05	185	40	4	46460e74cc613df9043f5404e7342aa13cc34873
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LAMB1 PRKCH VWF INSR	2.30e-05	186	40	4	a906020a8df6fcca474b278f746c553b177a56b4
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.30e-05	186	40	4	88e6246172d816806a498a5c1f38e699f2f5d7c2
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	PRKCB PRKCE JADE3 ADAM28	2.35e-05	187	40	4	af1327559f7e01bec070881cae52834917c3da65
ToppCell	P15-Mesenchymal\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 PRKCA ZYX SLC36A2	2.40e-05	188	40	4	f1ba0b661621a65c91432e62ba73531bdf18e7c1
ToppCell	COVID-19-lung-Artery_EC\|lung / Disease (COVID-19 only), tissue and cell type	HRH1 PRKCH VWF LEPR	2.40e-05	188	40	4	eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 PRKCH VWF INSR	2.45e-05	189	40	4	d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	LAMB1 ZYX SLC36A2 SLIT3	2.45e-05	189	40	4	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 PRKCH VWF INSR	2.45e-05	189	40	4	476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 PRKCH VWF INSR	2.45e-05	189	40	4	3fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCell	COVID-19-lung-Artery_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HRH1 PRKCH VWF LEPR	2.50e-05	190	40	4	07b675befcd1d0a9c90cb17b5d22323468325d51
ToppCell	LV-08._Macrophage\|World / Chamber and Cluster_Paper	HRH1 PRKCB DOCK8 ADAM28	2.55e-05	191	40	4	e7a0bc46ba9ba772636a583f3387748418e18832
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCE PRKCH VWF	2.55e-05	191	40	4	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	HRH1 LAMB1 PRKCH DOCK8	2.55e-05	191	40	4	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	PRKCH VWF ANKRD50 LEPR	2.60e-05	192	40	4	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 VWF LEPR INSR	2.60e-05	192	40	4	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	LPS-IL1RA+antiTNF-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCE PRKCH VWF	2.60e-05	192	40	4	04f5a2e3dd6beff027b89d66eefdd92036e041af
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRH1 VWF LEPR INSR	2.60e-05	192	40	4	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	LV-08._Macrophage\|LV / Chamber and Cluster_Paper	HRH1 PRKCB DOCK8 ADAM28	2.60e-05	192	40	4	7be12d580aaf2f2f1562203fcad3a44639b8c5a6
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCE PRKCH VWF	2.60e-05	192	40	4	c07d7b40b2aa4eb27ac85801c014a656e2fd01dc
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRKCE PRKCH VWF LEPR	2.66e-05	193	40	4	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRKCE PRKCH VWF LEPR	2.66e-05	193	40	4	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	Control-Endothelial-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCH VWF LEPR	2.66e-05	193	40	4	aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCell	Control-Endothelial\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCH VWF LEPR	2.66e-05	193	40	4	c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCE PRKCH ANKRD50	2.66e-05	193	40	4	a3636c35ed25aabe2f1aba016c9fe125327bbfaf
ToppCell	LPS-IL1RA-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCE PRKCH VWF	2.71e-05	194	40	4	43f92b0533e26633dc94cce554045d641ef8fd76
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRKCE PRKCH VWF LEPR	2.71e-05	194	40	4	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	HRH1 PRKCH VWF LEPR	2.71e-05	194	40	4	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	LPS-IL1RA-Endothelial-Endothelial\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HRH1 PRKCE PRKCH VWF	2.71e-05	194	40	4	1d39d968730a7e85b6161c1c8a6bd38afe9bcad7
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRKCE PRKCH VWF LEPR	2.71e-05	194	40	4	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_submucosal-gland\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CHAD NRAP PLA2G2C ADGRE3	2.71e-05	194	40	4	e90f6717e3421f8978d1fc1b2f30dcf69f6fcce7
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRKCE PRKCH VWF LEPR	2.71e-05	194	40	4	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRKCH VWF LEPR INSR	2.77e-05	195	40	4	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAMB1 ZYX SLC36A2 SLIT3	2.77e-05	195	40	4	3a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	LAMB1 ZYX SLC36A2 SLIT3	2.77e-05	195	40	4	2b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell	COVID-19-lung-Capillary_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRKCE PRKCH VWF LEPR	2.82e-05	196	40	4	ac28e9be288af6f00a841aea4ce4b99aed6b4505
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	HRH1 PRKCE VWF LEPR	2.88e-05	197	40	4	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HRH1 PRKCE VWF LEPR	2.88e-05	197	40	4	1ab86f5c05a3d8f352420e62277d5c79933063d8
ToppCell	COVID-19-lung-Capillary_1\|lung / Disease (COVID-19 only), tissue and cell type	PRKCE PRKCH VWF LEPR	2.88e-05	197	40	4	7e86ff9dafcbaaa7464d61484dd48bfeb7eae6e4
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_cell\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRKCB JADE3 DOCK8 ADAM28	2.94e-05	198	40	4	824461cf44098440ba8bc0df96735423ac65bda1
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRKCB JADE3 DOCK8 ADAM28	2.94e-05	198	40	4	863765ccc0205dc28864dae85af339c283194c96
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Capillary\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	PRKCE PRKCH VWF LEPR	3.05e-05	200	40	4	6c0498a5868891e8e22c03469d00669b20249b1a
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Capillary-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PRKCE PRKCH VWF LEPR	3.05e-05	200	40	4	7020045b933cb104fb99b79524cb0d4734b8636d
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Capillary\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	PRKCE PRKCH VWF LEPR	3.05e-05	200	40	4	e9913511a129bb3cee85e7ebf565b951dab91542
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CHAD ADAM28 SLC36A2	3.27e-05	69	40	3	2fd6df70cdc7477e4a3ebdf4537279a727ab1214
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CHAD ADAM28 SLC36A2	3.27e-05	69	40	3	8e14f411cbaea9cb9bcb9351b2421e71d5828ccc
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Myoc_(Myoc)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CHAD ADAM28 SLC36A2	3.27e-05	69	40	3	bc3170409d107c39534581d2f0b8d75f93519113
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PLA2G2C LEPR SLC36A2	1.15e-04	105	40	3	cec0bdfe2bbd87c7e84671c1eeafad17aec1cdb2
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2-Endothelial_Tip.Dcn.Rbp4_(Rbp4)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PLA2G2C LEPR SLC36A2	1.15e-04	105	40	3	c4b3f085c7e372e529d2c5d275faba403e830d48
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PLA2G2C LEPR SLC36A2	1.15e-04	105	40	3	dc5f6d62945a699734a71b8ab1d4266db6fb2918
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRKCH VWF ADGRE3	1.35e-04	111	40	3	9ba3590be8862c23b6e2917caed8bdbd9f9c2753
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRKCH VWF ADGRE3	1.35e-04	111	40	3	3e38efb22c47506ef2e2c1e19c79450e11d0ce56
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lcn2_(Lcn2)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	PRKCH VWF ADGRE3	1.35e-04	111	40	3	cd84f2a9102a6eb63226ecde11d4ece54ff99b48
ToppCell	PND01-03-samps-Myeloid-Granulocyte\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PRKCB RASGRP4 DOCK8	3.21e-04	149	40	3	7bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCell	PND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	PRKCB RASGRP4 DOCK8	3.21e-04	149	40	3	50f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LEPR ADGRE3 SLIT3	3.68e-04	156	40	3	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LEPR ADGRE3 SLIT3	3.68e-04	156	40	3	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB ZNF569 RHOBTB2	3.89e-04	159	40	3	74655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRKCH VWF LEPR	3.96e-04	160	40	3	33050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCell	facs-Lung-18m-Hematologic-myeloid-non-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRKCB RASGRP4 DOCK8	3.96e-04	160	40	3	bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	RASGRP4 PRKCH VWF	3.96e-04	160	40	3	04714d0b9bad4c11fa193ed168e2d84a4df39e2e
ToppCell	facs-Heart-LA-24m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ZYX SLIT3	4.03e-04	161	40	3	248487415a0601d57ef2a6692e22a61368d0b9c8
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCH VWF TRIM25	4.03e-04	161	40	3	a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCH VWF TRIM25	4.11e-04	162	40	3	0bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCell	facs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RASGRP4 DOCK8	4.11e-04	162	40	3	484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCB RASGRP4 DOCK8	4.11e-04	162	40	3	bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKCE VWF UBR4	4.11e-04	162	40	3	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCH VWF TRIM25	4.11e-04	162	40	3	5799a602ef8d83925907e8e34532428be7330228
ToppCell	normal_Lymph_Node-B_lymphocytes-Undetermined\|normal_Lymph_Node / Location, Cell class and cell subclass	PRKCB DOCK8 ADAM28	4.11e-04	162	40	3	91ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell	Control-APC-like-Monocytes\|Control / group, cell type (main and fine annotations)	CHAD ADAM28 ADGRE3	4.18e-04	163	40	3	4bc80a2c741d462724b6f3902377d48c57478932
ToppCell	10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory\|bone_marrow / Manually curated celltypes from each tissue	CHAD ADAM28 RHOBTB2	4.25e-04	164	40	3	746833f74095c0f25ce76baf1069f1848c231933
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCH VWF TRIM25	4.25e-04	164	40	3	6a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCH VWF TRIM25	4.25e-04	164	40	3	ec68954fc09b6850273b5e59caa6b09d02151097
ToppCell	Club-club-12\|World / Class top	CHAD LDB3 SLC36A2	4.33e-04	165	40	3	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LDB3 DOCK8 SLIT3	4.33e-04	165	40	3	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	LDB3 DOCK8 SLIT3	4.33e-04	165	40	3	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	PRKCH VWF LEPR	4.33e-04	165	40	3	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	Mild/Remission-B_memory-6\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CHAD PLA2G2C ZYX	4.41e-04	166	40	3	03e1a369d8a83b814def07e29cabb023226b4828
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	LEPR SLIT3 LAMA1	4.41e-04	166	40	3	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HRH1 PRKCH VWF	4.41e-04	166	40	3	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	frontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PRKCH VWF TRIM25	4.41e-04	166	40	3	27af6c906cff1d40d134f0386db7708869691121
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LEPR SLIT3 LAMA1	4.41e-04	166	40	3	7c2eee0a4f45795a956acf936b85bdb35f1b1624
Drug	AC1L1B58	LAMB1 PRKCA PRKCB PRKCE PRKCH LAMA1	9.16e-12	29	40	6	CID000001288
Drug	NCDC	HRH1 PRKCA PRKCB PRKCE PRKCH	1.23e-09	28	40	5	CID000001583
Drug	12-deoxyphorbol 13-phenylacetate	PRKCA PRKCB PRKCE PRKCH INSR	1.78e-09	30	40	5	CID000105100
Drug	N,n,n-tms	PRKCA PRKCB PRKCE PRKCH VWF	2.12e-09	31	40	5	CID006439410
Drug	octahydromezerein	PRKCA PRKCB PRKCE	5.02e-09	3	40	3	CID000164152
Drug	Ro 31-7549	HRH1 PRKCA PRKCB PRKCE PRKCH	7.12e-09	39	40	5	CID000002403
Drug	1-stearoyl-2-arachidonoyl-sn-glycerol	PRKCA PRKCB PRKCE PRKCH DAGLA	8.12e-09	40	40	5	CID000001398
Drug	AC1L1KEH	PRKCA PRKCB PRKCE PRKCH INSR	8.12e-09	40	40	5	CID000005462
Drug	mucic acid	PRKCA PRKCB PRKCE PRKCH VWF ADGRE3	9.69e-09	88	40	6	CID000000607
Drug	dansyl-DAG	PRKCA PRKCB PRKCE PRKCH	1.10e-08	15	40	4	CID000129493
Drug	RK-1409B	PRKCA PRKCB PRKCE PRKCH	1.10e-08	15	40	4	CID003036125
Drug	1-stearoyl-2-arachidonylglycerol	PRKCA PRKCB PRKCE PRKCH	1.10e-08	15	40	4	CID006443869
Drug	H-9 dihydrochloride	LAMB1 PRKCA PRKCB PRKCE PRKCH LAMA1	1.11e-08	90	40	6	CID000003544
Drug	aurothioglucose	PRKCA PRKCB PRKCE PRKCH LEPR INSR	1.11e-08	90	40	6	CID000006104
Drug	triphenylethylene	PRKCA PRKCB PRKCE PRKCH TRIM25	1.68e-08	46	40	5	CID000006025
Drug	AC1L1JQC	PRKCA PRKCB PRKCE PRKCH	1.91e-08	17	40	4	CID000005157
Drug	daphnoretin	PRKCA PRKCB PRKCE PRKCH	1.91e-08	17	40	4	CID005281406
Drug	dipalmitin	PRKCA PRKCB PRKCE PRKCH	2.45e-08	18	40	4	CID000068149
Drug	Cgp-42700	PRKCA PRKCB PRKCE PRKCH	2.45e-08	18	40	4	CID000188390
Drug	dihydrosterculic acid	PRKCA PRKCB PRKCE PRKCH	2.45e-08	18	40	4	CID000160788
Drug	TAPP-Br	PRKCA PRKCB PRKCE PRKCH	3.11e-08	19	40	4	CID000160326
Drug	sapintoxin A	PRKCA PRKCB PRKCE PRKCH	3.11e-08	19	40	4	CID000108085
Drug	KS-619-1	PRKCA PRKCB PRKCE PRKCH	4.78e-08	21	40	4	CID000128369
Drug	K-259-2	PRKCA PRKCB PRKCE PRKCH	4.78e-08	21	40	4	CID006438946
Drug	debromoaplysiatoxin	PRKCA PRKCB PRKCE PRKCH	4.78e-08	21	40	4	CID000002967
Drug	broussochalcone A	PRKCA PRKCB PRKCE PRKCH	4.78e-08	21	40	4	CID006438825
Drug	MDL 27,032	PRKCA PRKCB PRKCE PRKCH	4.78e-08	21	40	4	CID000163812
Drug	DAPH2	PRKCA PRKCB PRKCE PRKCH INSR	5.53e-08	58	40	5	CID006711154
Drug	ETYA	HRH1 PRKCA PRKCB PRKCE PRKCH DAGLA	6.92e-08	122	40	6	CID000001780
Drug	AC1L4NFY	PRKCA PRKCB PRKCE PRKCH	7.06e-08	23	40	4	CID000160335
Drug	NDGA	HRH1 PRKCA PRKCB PRKCE PRKCH PLA2G2C DAGLA	8.97e-08	216	40	7	CID000004534
Drug	methacholine	HRH1 PRKCA PRKCB PRKCE RASGRP4 PRKCH SLIT3	9.26e-08	217	40	7	CID000001993
Drug	AC1L1ET5	PRKCA PRKCB PRKCE PRKCH LAMA1	9.88e-08	65	40	5	CID000002936
Drug	AC1L1H7H	PRKCA PRKCB PRKCE PRKCH DAGLA	1.24e-07	68	40	5	CID000004009
Drug	beta-tocopherol	PRKCA PRKCB PRKCE PRKCH	1.39e-07	27	40	4	CID000008989
Drug	ilmofosine	PRKCA PRKCB PRKCE PRKCH	1.39e-07	27	40	4	CID000055008
Drug	C15720	PRKCA PRKCB PRKCE PRKCH	1.39e-07	27	40	4	CID000003979
Drug	pseudohypericin	PRKCA PRKCB PRKCE PRKCH	1.39e-07	27	40	4	CID005281751
Drug	R59949	PRKCA PRKCB PRKCE PRKCH DAGLA	1.44e-07	70	40	5	CID000657356
Drug	ONO-RS-082	PRKCA PRKCB PRKCE PRKCH DAGLA	1.44e-07	70	40	5	CID006438389
Drug	4 alpha-phorbol 12,13-didecanoate	HRH1 PRKCA PRKCB PRKCE PRKCH	1.44e-07	70	40	5	CID000452543
Drug	bisindolylmaleimide II	PRKCA PRKCB PRKCE PRKCH	1.62e-07	28	40	4	CID000002397
Drug	bisindolylmaleimide V	PRKCA PRKCB PRKCE PRKCH	1.62e-07	28	40	4	CID000002400
Drug	aplysiatoxin	PRKCA PRKCB PRKCE PRKCH	1.62e-07	28	40	4	CID000040465
Drug	HBDDE	PRKCA PRKCB PRKCE PRKCH	1.62e-07	28	40	4	CID000003568
Drug	SC-10	PRKCA PRKCB PRKCE PRKCH	1.62e-07	28	40	4	CID000005175
Drug	AC1Q6DXY	PRKCA PRKCB PRKCE PRKCH	1.88e-07	29	40	4	CID000003719
Drug	Polychlorinated biphenyls	PRKCA PRKCB PRKCE PRKCH	1.88e-07	29	40	4	CID000006636
Drug	Gf 109	PRKCA PRKCB PRKCE PRKCH	2.17e-07	30	40	4	CID000196144
Drug	AC1L3G0K	PRKCA PRKCB PRKCE PRKCH	2.17e-07	30	40	4	CID000114822
Drug	R59022	PRKCA PRKCB PRKCE PRKCH DAGLA	2.18e-07	76	40	5	CID000003012
Drug	miltefosine	PRKCA PRKCB PRKCE PRKCH ADAM28	2.48e-07	78	40	5	CID000003599
Drug	NSC35770	PRKCA PRKCB PRKCE PRKCH TRIM25	2.82e-07	80	40	5	CID000002800
Drug	nM-1	HRH1 PRKCA PRKCB PRKCE PRKCH INSR	2.86e-07	155	40	6	CID000445754
Drug	I-Q-S	LAMB1 PRKCA PRKCB PRKCE PRKCH LAMA1	2.97e-07	156	40	6	CID000003540
Drug	CGS 9343B	PRKCA PRKCB PRKCE PRKCH	3.22e-07	33	40	4	CID000065909
Drug	naphthalenesulfonamide	PRKCA PRKCB PRKCE PRKCH	3.22e-07	33	40	4	CID000163571
Drug	AC1L1FGW	PRKCA PRKCB PRKCE PRKCH	3.22e-07	33	40	4	CID000003231
Drug	1 Em	PRKCA PRKCB PRKCE PRKCH DAGLA	3.39e-07	83	40	5	CID000446621
Drug	AC1NSKHR	PRKCA PRKCB PRKCE PRKCH	3.65e-07	34	40	4	CID005311362
Drug	h x mg	PRKCA PRKCB PRKCE PRKCH	3.65e-07	34	40	4	CID000001380
Drug	4-O-methyl-TPA	PRKCA PRKCB PRKCE PRKCH	3.65e-07	34	40	4	CID000072292
Drug	K 252	PRKCA PRKCB PRKCE PRKCH INSR	4.55e-07	88	40	5	CID000003813
Drug	AG213	PRKCA PRKCB PRKCE PRKCH DAGLA	4.81e-07	89	40	5	CID005328803
Drug	DB04780	LAMB1 PRKCA PRKCB PRKCE PRKCH VWF	4.93e-07	170	40	6	CID005459389
Drug	1,3-diolein	PRKCA PRKCB PRKCE PRKCH INSR	5.09e-07	90	40	5	CID000033120
Drug	HOE 694	PRKCA PRKCB PRKCE PRKCH	5.17e-07	37	40	4	CID000123840
Drug	iso-H7	PRKCA PRKCB PRKCE PRKCH	5.17e-07	37	40	4	CID000001352
Drug	norathyriol	PRKCA PRKCB PRKCE PRKCH	5.17e-07	37	40	4	CID005281656
Drug	Fim 1	PRKCA PRKCB PRKCE PRKCH	5.17e-07	37	40	4	CID000132906
Drug	AC1L1BDQ	PRKCA PRKCB PRKCE PRKCH DAGLA INSR	5.47e-07	173	40	6	CID000001394
Drug	Jmv 180	PRKCA PRKCB PRKCE PRKCH	5.77e-07	38	40	4	CID003035023
Drug	12-deoxyphorbol 13-isobutyrate	PRKCA PRKCB PRKCE PRKCH	6.42e-07	39	40	4	CID000107855
Drug	digoxigenine	PRKCA PRKCB PRKCE PRKCH	7.13e-07	40	40	4	CID000015478
Drug	Go6983	PRKCA PRKCB PRKCE PRKCH	7.13e-07	40	40	4	CID000003499
Drug	propranolol	HRH1 PRKCA PRKCB PRKCE PRKCH VWF PLA2G2C DAGLA	7.36e-07	434	40	8	CID000004946
Drug	12-deoxyphorbol 13-acetate	PRKCA PRKCB PRKCE PRKCH	7.89e-07	41	40	4	CID000004962
Drug	indo-1	HRH1 PRKCA PRKCB PRKCE PRKCH	8.19e-07	99	40	5	CID000105060
Drug	antibiotic from Streptomyces	PRKCA PRKCB PRKCE PRKCH	8.71e-07	42	40	4	CID000005153
Drug	benzenesulfonate	PRKCA PRKCB PRKCE PRKCH	8.71e-07	42	40	4	CID000007371
Drug	PEP005	PRKCA PRKCB PRKCE PRKCH	8.71e-07	42	40	4	CID006918670
Drug	p-bromophenacyl bromide	PRKCA PRKCB PRKCE PRKCH DAGLA	9.50e-07	102	40	5	CID000007454
Drug	benzoyl	PRKCA PRKCB PRKCE PRKCH	9.59e-07	43	40	4	CID000007187
Drug	AC1LDMDX	PRKCA PRKCB PRKCE PRKCH	9.59e-07	43	40	4	CID000621355
Drug	SC-9	PRKCA PRKCB PRKCE PRKCH	9.59e-07	43	40	4	CID000124172
Drug	4 alpha-phorbol	HRH1 PRKCA PRKCB PRKCE PRKCH	9.97e-07	103	40	5	CID000028683
Drug	rhodamine 6G	PRKCA PRKCB PRKCE PRKCH	1.05e-06	44	40	4	CID000013806
Drug	loperamide	HRH1 PRKCA PRKCB PRKCE PRKCH	1.10e-06	105	40	5	CID000003954
Drug	1-(5-isoquinolinesulfonyl)-2-methylpiperazine	HRH1 LAMB1 PRKCA PRKCB PRKCE PRKCH LAMA1	1.12e-06	314	40	7	CID000003542
Drug	20-HETE	PRKCA PRKCB PRKCE PRKCH DAGLA	1.15e-06	106	40	5	CID005283157
Drug	niguldipine	PRKCA PRKCB PRKCE PRKCH	1.15e-06	45	40	4	CID000001236
Drug	procyanidin B2	PRKCA PRKCB PRKCE PRKCH	1.15e-06	45	40	4	CID000122738
Drug	myricitrin	PRKCA PRKCB PRKCE PRKCH	1.15e-06	45	40	4	CID005281673
Drug	E)-4-hydroxytamoxifen	PRKCA PRKCB PRKCE PRKCH TRIM25 INSR	1.17e-06	197	40	6	CID000063062
Drug	phosphine oxide	PRKCA PRKCB PRKCE PRKCH LEPR	1.20e-06	107	40	5	CID000166931
Drug	ruboxistaurin	PRKCA PRKCB PRKCE PRKCH INSR	1.20e-06	107	40	5	CID000153999
Drug	NPC 15437	PRKCA PRKCB PRKCE PRKCH	1.26e-06	46	40	4	CID000004548
Drug	3,4,5-trimethoxybenzoic acid	PRKCA PRKCB PRKCE PRKCH	1.38e-06	47	40	4	CID000008357
Drug	chloroethylclonidine	PRKCA PRKCB PRKCE PRKCH	1.38e-06	47	40	4	CID000104973
Drug	Hoe 140	HRH1 PRKCA PRKCB PRKCE PRKCH	1.38e-06	110	40	5	CID000071362
Disease	dilated cardiomyopathy (is_implicated_in)	PRKCA PRKCB LDB3 LEPR	2.49e-07	43	37	4	DOID:12930 (is_implicated_in)
Disease	short bowel syndrome (biomarker_via_orthology)	LEPR INSR	1.53e-06	2	37	2	DOID:10605 (biomarker_via_orthology)
Disease	alcohol use disorder (implicated_via_orthology)	PRKCA PRKCB PRKCE PRKCH CREBBP	4.40e-06	195	37	5	DOID:1574 (implicated_via_orthology)
Disease	Hyperglycemia, Postprandial	PRKCB LEPR INSR	7.20e-06	30	37	3	C1855520
Disease	Hyperglycemia	PRKCB LEPR INSR	7.20e-06	30	37	3	C0020456
Disease	Streptozotocin Diabetes	PRKCA PRKCE LEPR INSR	1.02e-05	108	37	4	C0038433
Disease	Diabetes Mellitus, Experimental	PRKCA PRKCE LEPR INSR	1.02e-05	108	37	4	C0011853
Disease	Alloxan Diabetes	PRKCA PRKCE LEPR INSR	1.02e-05	108	37	4	C0002152
Disease	hypertension (implicated_via_orthology)	PRKCA PRKCB PRKCE LEPR	2.00e-05	128	37	4	DOID:10763 (implicated_via_orthology)
Disease	Non-alcoholic Fatty Liver Disease	PRKCA PRKCE LAMA1	9.38e-05	70	37	3	C0400966
Disease	Nonalcoholic Steatohepatitis	PRKCA PRKCE LAMA1	9.38e-05	70	37	3	C3241937
Disease	chronic kidney disease (implicated_via_orthology)	LEPR INSR	1.00e-04	12	37	2	DOID:784 (implicated_via_orthology)
Disease	Diabetic Asymmetric Polyneuropathy	LEPR INSR	1.38e-04	14	37	2	C0393835
Disease	Diabetic Neuralgia	LEPR INSR	1.38e-04	14	37	2	C0751074
Disease	Diabetic Neuropathies	LEPR INSR	1.38e-04	14	37	2	C0011882
Disease	Asymmetric Diabetic Proximal Motor Neuropathy	LEPR INSR	1.38e-04	14	37	2	C0271674
Disease	Symmetric Diabetic Proximal Motor Neuropathy	LEPR INSR	1.38e-04	14	37	2	C0271673
Disease	Diabetic Mononeuropathy	LEPR INSR	1.38e-04	14	37	2	C0271678
Disease	Diabetic Autonomic Neuropathy	LEPR INSR	1.38e-04	14	37	2	C0271686
Disease	Diabetic Amyotrophy	LEPR INSR	1.38e-04	14	37	2	C0271685
Disease	Diabetic Polyneuropathies	LEPR INSR	1.38e-04	14	37	2	C0271680
Disease	amino acid measurement	SHPRH LAMB1 PRKCE VWF ADAM28 SLIT3	1.82e-04	678	37	6	EFO_0005134
Disease	hyperglycemia (implicated_via_orthology)	PRKCB LEPR	2.06e-04	17	37	2	DOID:4195 (implicated_via_orthology)
Disease	Colorectal Carcinoma	HRH1 PRKCB PRKCE CAMSAP2 ZNF569 LAMA1	2.20e-04	702	37	6	C0009402
Disease	Adenocarcinoma of large intestine	PRKCA PRKCB PRKCH	2.39e-04	96	37	3	C1319315
Disease	Colorectal Neoplasms	PRKCB PRKCE ZNF569 LAMA1	3.93e-04	277	37	4	C0009404
Disease	immature platelet fraction	VWF DOCK8 RTTN	3.97e-04	114	37	3	EFO_0009187
Disease	Drug habituation	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0013170
Disease	Substance-Related Disorders	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0236969
Disease	Drug abuse	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0013146
Disease	Drug Use Disorders	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0013222
Disease	Drug Dependence	PRKCE PRKCH INSR	4.07e-04	115	37	3	C1510472
Disease	Substance Dependence	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0038580
Disease	Substance Use Disorders	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0038586
Disease	Organic Mental Disorders, Substance-Induced	PRKCE PRKCH INSR	4.07e-04	115	37	3	C0029231
Disease	lifestyle measurement, alcohol consumption measurement	HRH1 CHAD VWF	4.07e-04	115	37	3	EFO_0007878, EFO_0010724
Disease	Prescription Drug Abuse	PRKCE PRKCH INSR	4.07e-04	115	37	3	C4316881
Disease	Substance abuse problem	PRKCE PRKCH INSR	4.17e-04	116	37	3	C0740858
Disease	immature platelet measurement	VWF DOCK8 RTTN	4.50e-04	119	37	3	EFO_0803541
Disease	Impaired glucose tolerance	LEPR INSR	4.51e-04	25	37	2	C0271650
Disease	Endogenous Hyperinsulinism	LEPR INSR	4.88e-04	26	37	2	C1257963
Disease	Exogenous Hyperinsulinism	LEPR INSR	4.88e-04	26	37	2	C1257964
Disease	Compensatory Hyperinsulinemia	LEPR INSR	4.88e-04	26	37	2	C1257965
Disease	Hyperinsulinism	LEPR INSR	5.67e-04	28	37	2	C0020459
Disease	platelet measurement	VWF DOCK8 SLC36A2 RTTN	6.37e-04	315	37	4	EFO_0005036
Disease	ulcerative colitis	LAMB1 PRKCB UBR4 SLIT3	8.02e-04	335	37	4	EFO_0000729
Disease	non-alcoholic fatty liver disease (implicated_via_orthology)	LEPR INSR	9.38e-04	36	37	2	DOID:0080208 (implicated_via_orthology)
Disease	Nodular glomerulosclerosis	PRKCE LEPR	1.22e-03	41	37	2	C0017667

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKCKGHAVCDHELQC	ADAM28	631	Q9UKQ2
THCQAGKACQVAHCA	CREBBP	396	Q92793
QLIALCCYHAKHCQE	CREBBP	1821	Q92793
LCAVIRALHQHCACK	DOP1A	1641	Q5JWR5
HKLQHCLQEKSNCCN	ANKRD50	31	Q9ULJ7
NCHCHSDLQHVICDK	CHAD	26	O15335
HCRLKACECDKQSVH	PLA2G2C	106	Q5R387
HDTCFICAVCHVNLE	LDB3	691	O75112
RILDCQNHTCMKECH	NFXL1	666	Q6ZNB6
CIDQIWHKACFHCEV	NRAP	21	Q86VF7
CQVCTCVVHKRCHEL	PRKCE	201	Q02156
LCCHKHCRDQVKVEC	RASGRP4	576	Q8TDF6
ACKKCNCNEHSISCH	LAMB1	331	P07942
FQMVHCNCSVHECCE	LEPR	181	P48357
QCQVCCFVVHKRCHE	PRKCB	66	P05771
CHQYVIHNNKCIPEC	INSR	301	P06213
CACKILQALFQCDHV	CDC45	31	O75419
VEQCFDLCHQVLHHC	DOCK8	1501	Q8NF50
IHVVHNHPAEQCCCC	DAGLA	606	Q9Y4D2
MVIAFCKNCCNEHLH	HRH1	436	P35367
NKHIIQNALAHCCLA	CAMSAP2	1361	Q08AD1
DMVFCDKCNVCVHQA	JADE3	216	Q92613
CTCVEKNACKACHPH	PRR14L	1301	Q5THK1
HCCLEITKECLGVHN	RTTN	636	Q86VV8
QCQVCCFVVHKRCHE	PRKCA	66	P17252
AKNCRACECHVKGSH	LAMA1	896	P25391
CLHHICTNYNNVCRK	RHOBTB2	631	Q9BYZ6
FIACHCMHILVKCAQ	SLC36A2	96	Q495M3
QCLKCHLWQHAKCVN	SHPRH	676	Q149N8
CFLIHVNKSHTMCNC	ADGRE3	321	Q9BY15
DDCVAHKCRHGAQCV	SLIT3	1076	O75094
HCQICHCDVVNLTCE	VWF	1221	P04275
NIACKNSCKNCHQSH	RNASE8	86	Q8TDE3
HSECICHICLVEHKT	TRIM25	171	Q14258
DCHNNVKCLMRKEHC	ZNF569	151	Q5MCW4
HIACFTCHQCAQQLQ	ZYX	406	Q15942
CTVRKDLHQNCPHCQ	SMYD5	101	Q6GMV2
CTVCAKVCHKDHEIS	UBR4	1691	Q5T4S7
LCVNSHQHSQCQDCK	ZFYVE26	511	Q68DK2
CFEHRVNVCEHCLVA	ZFPL1	16	O95159
VNVCEHCLVANHAKC	ZFPL1	21	O95159
YQCQVCTCVVHKRCH	PRKCH	201	P24723
CTCVVHKRCHHLIVT	PRKCH	206	P24723
HKRCHHLIVTACTCQ	PRKCH	211	P24723