Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 demethylase activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

4.42e-1128476GO:0141052
GeneOntologyMolecularFunctionhistone demethylase activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

8.60e-1131476GO:0032452
GeneOntologyMolecularFunctionprotein demethylase activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.06e-1032476GO:0140457
GeneOntologyMolecularFunctionpotassium ion transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 ABCC8

1.67e-10167479GO:0015079
GeneOntologyMolecularFunctionmonoatomic cation channel activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8 PKD1L1

3.28e-103434711GO:0005261
GeneOntologyMolecularFunctionhistone H3K9me2/H3K9me3 demethylase activity

KDM4D KDM4A KDM4E KDM4B

4.03e-106474GO:0140684
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

4.76e-104594712GO:0005216
GeneOntologyMolecularFunctiondemethylase activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

8.06e-1044476GO:0032451
GeneOntologyMolecularFunctionchannel activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

2.18e-095254712GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

2.23e-095264712GO:0022803
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8 PKD1L1

7.94e-094654711GO:0046873
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

9.09e-0965476GO:0016706
GeneOntologyMolecularFunctionpotassium channel activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8

1.92e-08128477GO:0005267
GeneOntologyMolecularFunctionhistone H3K9 demethylase activity

KDM4D KDM4A KDM4E KDM4B

2.65e-0814474GO:0032454
GeneOntologyMolecularFunctiongated channel activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB CNGB1 ABCC8

7.17e-08334479GO:0022836
GeneOntologyMolecularFunctiondioxygenase activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.09e-0798476GO:0051213
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

1.26e-077584712GO:0015318
GeneOntologyMolecularFunctionvoltage-gated potassium channel activity

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8

1.39e-07102476GO:0005249
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8 PKD1L1

1.67e-076274711GO:0022890
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

2.06e-077934712GO:0015075
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB ABCC8

2.15e-07182477GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB ABCC8

2.32e-07184477GO:0022832
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8 PKD1L1

2.96e-076644711GO:0008324
GeneOntologyMolecularFunctiontransmembrane transporter activity

TMEM38A SLC19A2 SV2C ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

3.18e-0711804714GO:0022857
GeneOntologyMolecularFunctiondelayed rectifier potassium channel activity

KCNA1 KCNA6 KCNB2 KCNB1

5.29e-0728474GO:0005251
GeneOntologyMolecularFunctiontransporter activity

TMEM38A SLC19A2 SV2C ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

9.25e-0712894714GO:0005215
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8

1.46e-06152476GO:0022843
GeneOntologyMolecularFunctionsulfonylurea receptor activity

ABCC9 ABCC8

5.42e-062472GO:0008281
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

6.00e-06194476GO:0016705
GeneOntologyMolecularFunctionhistone modifying activity

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.54e-05229476GO:0140993
GeneOntologyMolecularFunctioncalcium, potassium:sodium antiporter activity

SLC24A1 SLC24A2

5.40e-055472GO:0008273
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5D KDM5C

8.09e-056472GO:0034647
GeneOntologyMolecularFunctionATP-activated inward rectifier potassium channel activity

ABCC9 ABCC8

8.09e-056472GO:0015272
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5D KDM5C

1.50e-048472GO:0032453
GeneOntologyMolecularFunctioncalcium channel activity

SLC24A1 SLC24A2 CNGB1 PKD1L1

2.39e-04129474GO:0005262
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GPR37L1 ABCC9 SMO FCRL5 OR4K13 AXL ABCC8 GPR148 GABBR1 EPHA4 EPHB1

2.39e-0413534711GO:0004888
GeneOntologyMolecularFunctioncalcium:sodium antiporter activity

SLC24A1 SLC24A2

2.41e-0410472GO:0005432
GeneOntologyMolecularFunctionhistone H3K36 demethylase activity

KDM4A KDM4B

2.94e-0411472GO:0051864
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

TMEM38A ABCC9 CNGB1 ABCC8

3.27e-04140474GO:0099094
GeneOntologyMolecularFunctionJUN kinase kinase kinase activity

MAP3K9 MAP3K21

3.53e-0412472GO:0004706
GeneOntologyMolecularFunctionoxidoreductase activity

KDM4D KDM4A FRRS1 KDM5D KDM4E AIFM1 KDM5C KDM4B

3.77e-04766478GO:0016491
GeneOntologyMolecularFunctioncalcium:monoatomic cation antiporter activity

SLC24A1 SLC24A2

4.16e-0413472GO:0015368
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

SLC24A1 SLC24A2 CNGB1 PKD1L1

4.35e-04151474GO:0015085
GeneOntologyMolecularFunctionprotein kinase activity

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

4.73e-04600477GO:0004672
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

AXL EPHA4 EPHB1

4.82e-0465473GO:0004714
GeneOntologyMolecularFunctionRNA 7-methylguanosine cap binding

CYFIP1 CYFIP2

4.85e-0414472GO:0000340
GeneOntologyMolecularFunctiontransmembrane-ephrin receptor activity

EPHA4 EPHB1

5.58e-0415472GO:0005005
GeneOntologyMolecularFunctiontransmembrane transporter binding

ABCC9 KCNB2 KCNB1 ABCC8

7.10e-04172474GO:0044325
GeneOntologyMolecularFunctionephrin receptor activity

EPHA4 EPHB1

9.04e-0419472GO:0005003
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC24A1 SLC24A2

9.04e-0419472GO:0022821
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

AXL EPHA4 EPHB1

1.05e-0385473GO:0019199
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

TMEM38A ABCC9 CNGB1 ABCC8

1.09e-03193474GO:0015276
GeneOntologyMolecularFunctionRNA cap binding

CYFIP1 CYFIP2

1.11e-0321472GO:0000339
GeneOntologyMolecularFunctionligand-gated channel activity

TMEM38A ABCC9 CNGB1 ABCC8

1.18e-03197474GO:0022834
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

1.26e-03709477GO:0016773
GeneOntologyMolecularFunctionMAP kinase kinase kinase activity

MAP3K9 MAP3K21

1.83e-0327472GO:0004709
GeneOntologyMolecularFunctionkinase activity

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

1.93e-03764477GO:0016301
GeneOntologyMolecularFunctioninward rectifier potassium channel activity

ABCC9 ABCC8

1.97e-0328472GO:0005242
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC24A1 SLC24A2

4.60e-0343472GO:0140828
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

AXL EPHA4 EPHB1

4.81e-03145473GO:0004713
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ABCC9 SLC24A1 SLC24A2 ABCC8

5.42e-03301474GO:0022853
GeneOntologyMolecularFunctionprotein serine/threonine/tyrosine kinase activity

MAP3K9 RPS6KA1

5.48e-0347472GO:0004712
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC9 ABCC8

5.94e-0349472GO:0140359
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

6.01e-03938477GO:0016772
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC24A1 SLC24A2 CNGB1

7.59e-03171473GO:0015081
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ABCC9 ABCC8

9.37e-0362472GO:0019829
GeneOntologyMolecularFunctionprotein serine kinase activity

MAP3K9 MAP3K21 MAPK13 RPS6KA1

1.04e-02363474GO:0106310
GeneOntologyBiologicalProcesspotassium ion transport

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8

4.54e-102724710GO:0006813
GeneOntologyBiologicalProcesspotassium ion transmembrane transport

TMEM38A ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 ABCC8

2.32e-09232479GO:0071805
GeneOntologyBiologicalProcessmetal ion transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

2.29e-0710004713GO:0030001
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

2.77e-0710174713GO:0098660
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8 PKD1L1

7.28e-079224712GO:0098662
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

7.90e-0711154713GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8 PKD1L1

9.13e-079424712GO:0098655
GeneOntologyBiologicalProcessmonoatomic cation transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

1.20e-0611574713GO:0006812
GeneOntologyBiologicalProcessaction potential

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8

6.12e-06201476GO:0001508
GeneOntologyBiologicalProcessresponse to abiotic stimulus

ABCC9 KDM4D CYFIP1 KCNA1 KDM4E SLC24A1 MAPK13 CNGB1 AIFM1 ABCC8 PKD1L1 EPHA4 EPHB1

7.20e-0613614713GO:0009628
GeneOntologyBiologicalProcessmonoatomic ion transport

TMEM38A ABCC9 KCNA1 FCRL5 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8 PKD1L1

7.99e-0613744713GO:0006811
GeneOntologyBiologicalProcessnegative regulation of synaptic transmission

KCNB1 SLC24A1 SLC24A2 GABBR1

3.30e-0580474GO:0050805
GeneOntologyBiologicalProcessregulation of membrane potential

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CNGB1 ABCC8 GABBR1

3.43e-05559478GO:0042391
GeneOntologyBiologicalProcessanterograde trans-synaptic signaling

SV2C CYFIP1 KCNB1 SLC24A1 SLC24A2 ABCC8 RPS6KA1 GABBR1 EPHA4 EPHB1

3.78e-059314710GO:0098916
GeneOntologyBiologicalProcesschemical synaptic transmission

SV2C CYFIP1 KCNB1 SLC24A1 SLC24A2 ABCC8 RPS6KA1 GABBR1 EPHA4 EPHB1

3.78e-059314710GO:0007268
GeneOntologyBiologicalProcesstrans-synaptic signaling

SV2C CYFIP1 KCNB1 SLC24A1 SLC24A2 ABCC8 RPS6KA1 GABBR1 EPHA4 EPHB1

4.06e-059394710GO:0099537
GeneOntologyBiologicalProcessaxon guidance

SMO ANOS1 CYFIP1 CYFIP2 EPHA4 EPHB1

4.41e-05285476GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

SMO ANOS1 CYFIP1 CYFIP2 EPHA4 EPHB1

4.49e-05286476GO:0097485
GeneOntologyBiologicalProcesssynaptic signaling

SV2C CYFIP1 KCNB1 SLC24A1 SLC24A2 ABCC8 RPS6KA1 GABBR1 EPHA4 EPHB1

5.63e-059764710GO:0099536
GeneOntologyBiologicalProcessinorganic ion homeostasis

TMEM38A TMEM174 FRRS1 KCNA1 FCRL5 SLC24A1 SLC24A2 CNGB1

7.28e-05622478GO:0098771
GeneOntologyBiologicalProcessastrocyte differentiation

GPR37L1 SMO KDM4A EPHA4

9.56e-05105474GO:0048708
GeneOntologyBiologicalProcessnerve development

KCNA1 CNGB1 EPHA4 EPHB1

1.10e-04109474GO:0021675
GeneOntologyBiologicalProcessmodulation of chemical synaptic transmission

SV2C CYFIP1 KCNB1 SLC24A1 SLC24A2 GABBR1 EPHA4 EPHB1

1.13e-04663478GO:0050804
GeneOntologyBiologicalProcessregulation of trans-synaptic signaling

SV2C CYFIP1 KCNB1 SLC24A1 SLC24A2 GABBR1 EPHA4 EPHB1

1.15e-04664478GO:0099177
GeneOntologyBiologicalProcessregulation of astrocyte differentiation

GPR37L1 KDM4A EPHA4

1.28e-0443473GO:0048710
GeneOntologyBiologicalProcesslong-term synaptic depression

KCNB1 SLC24A1 SLC24A2

1.38e-0444473GO:0060292
GeneOntologyBiologicalProcesspositive regulation of neurotrophin TRK receptor signaling pathway

CYFIP1 CYFIP2

1.41e-048472GO:0051388
GeneOntologyBiologicalProcessepithelial cell proliferation involved in liver morphogenesis

SMO FGL1 RPS6KA1

1.57e-0446473GO:0072575
GeneOntologyBiologicalProcesshepatocyte proliferation

SMO FGL1 RPS6KA1

1.57e-0446473GO:0072574
GeneOntologyBiologicalProcessliver morphogenesis

SMO FGL1 RPS6KA1

1.90e-0449473GO:0072576
GeneOntologyBiologicalProcessresponse to hydrogen peroxide

ABCC9 MAPK13 AIFM1 AXL

1.93e-04126474GO:0042542
GeneOntologyBiologicalProcesspositive regulation of hepatic stellate cell activation

SMO RPS6KA1

2.26e-0410472GO:2000491
GeneOntologyBiologicalProcessresponse to reactive oxygen species

GPR37L1 ABCC9 MAPK13 AIFM1 AXL

2.36e-04246475GO:0000302
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

TMEM38A FCRL5 SLC24A1 SLC24A2 CNGB1 PKD1L1

2.52e-04392476GO:0070588
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

ABCC9 SLC24A1 SLC24A2 ABCC8

3.05e-04142474GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

ABCC9 SLC24A1 SLC24A2 ABCC8

3.05e-04142474GO:0098659
GeneOntologyBiologicalProcessnegative regulation of gliogenesis

GPR37L1 KDM4A ABCC8

3.82e-0462473GO:0014014
GeneOntologyBiologicalProcesschemical homeostasis

TMEM38A TMEM174 FRRS1 KCNA1 FCRL5 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8

4.23e-0412494710GO:0048878
GeneOntologyBiologicalProcesspositive regulation of chromatin binding

KDM4D KDM4E

4.54e-0414472GO:0035563
GeneOntologyBiologicalProcessregulation of hepatic stellate cell activation

SMO RPS6KA1

4.54e-0414472GO:2000489
GeneOntologyBiologicalProcessleft/right axis specification

SMO PKD1L1

4.54e-0414472GO:0070986
GeneOntologyBiologicalProcesscranial nerve development

KCNA1 CNGB1 EPHB1

4.80e-0467473GO:0021545
GeneOntologyBiologicalProcessregulation of nervous system development

GPR37L1 SMO KDM4A CYFIP1 ABCC8 EPHA4 EPHB1

4.97e-04625477GO:0051960
GeneOntologyBiologicalProcessaxon development

SMO ANOS1 CYFIP1 KCNA1 CYFIP2 EPHA4 EPHB1

5.84e-04642477GO:0061564
GeneOntologyBiologicalProcessdetection of external stimulus

KCNA1 CNGB1 PKD1L1 EPHB1

6.44e-04173474GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

KCNA1 CNGB1 PKD1L1 EPHB1

6.72e-04175474GO:0009582
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair via nonhomologous end joining

KDM4D KDM4E

6.76e-0417472GO:2001034
GeneOntologyBiologicalProcessregulation of neurotrophin TRK receptor signaling pathway

CYFIP1 CYFIP2

6.76e-0417472GO:0051386
GeneOntologyBiologicalProcessintracellular chemical homeostasis

TMEM38A FRRS1 FCRL5 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8

6.86e-04866478GO:0055082
GeneOntologyBiologicalProcesspositive regulation of endopeptidase activity

AIFM1 GRAMD4 CYFIP2 EPHA4

7.01e-04177474GO:0010950
GeneOntologyBiologicalProcesscellular response to reactive oxygen species

GPR37L1 MAPK13 AIFM1 AXL

7.16e-04178474GO:0034614
GeneOntologyBiologicalProcessresponse to L-glutamate

KCNB1 AIFM1

7.60e-0418472GO:1902065
GeneOntologyBiologicalProcesshepatic stellate cell activation

SMO RPS6KA1

7.60e-0418472GO:0035733
GeneOntologyBiologicalProcesscellular response to hydrogen peroxide

MAPK13 AIFM1 AXL

8.66e-0482473GO:0070301
GeneOntologyBiologicalProcessregulation of endopeptidase activity

AIFM1 GRAMD4 RPS6KA1 CYFIP2 EPHA4

9.24e-04332475GO:0052548
GeneOntologyBiologicalProcessresponse to radiation

KDM4D KDM4E SLC24A1 MAPK13 CNGB1 ABCC8

9.39e-04503476GO:0009314
GeneOntologyBiologicalProcesspositive regulation of peptidase activity

AIFM1 GRAMD4 CYFIP2 EPHA4

9.49e-04192474GO:0010952
GeneOntologyBiologicalProcesscalcium ion transport

TMEM38A FCRL5 SLC24A1 SLC24A2 CNGB1 PKD1L1

9.98e-04509476GO:0006816
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

TMEM38A FRRS1 KCNA1 FCRL5 SLC24A1 SLC24A2 CNGB1

1.01e-03705477GO:0055080
GeneOntologyBiologicalProcessregulation of neurogenesis

GPR37L1 SMO KDM4A CYFIP1 ABCC8 EPHA4

1.06e-03515476GO:0050767
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

TMEM38A FRRS1 KCNA1 FCRL5 SLC24A1 SLC24A2 CNGB1

1.12e-03717477GO:0050801
GeneOntologyBiologicalProcessoptic nerve development

KCNA1 EPHB1

1.14e-0322472GO:0021554
GeneOntologyBiologicalProcessnegative regulation of astrocyte differentiation

GPR37L1 KDM4A

1.14e-0322472GO:0048712
GeneOntologyBiologicalProcessdetection of stimulus

SMO KCNA1 OR4K13 CNGB1 GPR148 PKD1L1 EPHB1

1.16e-03722477GO:0051606
GeneOntologyBiologicalProcessregulation of neuron apoptotic process

SMO KCNB1 AIFM1 AXL EPHA4

1.24e-03355475GO:0043523
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

TMEM38A FCRL5 SLC24A1 SLC24A2 CNGB1

1.31e-03359475GO:0006874
GeneOntologyBiologicalProcesscellular response to oxygen-containing compound

GPR37L1 ABCC9 SMO CYFIP1 KCNB1 MAPK13 AIFM1 AXL ABCC8 EPHA4

1.34e-0314504710GO:1901701
GeneOntologyBiologicalProcessfibroblast activation

SMO RPS6KA1

1.36e-0324472GO:0072537
GeneOntologyBiologicalProcessregulation of chromatin binding

KDM4D KDM4E

1.36e-0324472GO:0035561
GeneOntologyBiologicalProcessmuscle system process

TMEM38A ABCC9 KDM4A KCNA1 KCNB2 ABCC8

1.44e-03547476GO:0003012
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

TMEM38A FCRL5 SLC24A1 SLC24A2

1.49e-03217474GO:0097553
GeneOntologyBiologicalProcesscellular homeostasis

TMEM38A FRRS1 FCRL5 KCNB1 SLC24A1 SLC24A2 CNGB1 ABCC8

1.53e-03981478GO:0019725
GeneOntologyBiologicalProcesscellular response to chemical stress

GPR37L1 ABCC9 MAPK13 AIFM1 AXL

1.62e-03377475GO:0062197
GeneOntologyBiologicalProcessprotein homooligomerization

KCNA1 KCNA6 KCNB2 KCNB1

1.68e-03224474GO:0051260
GeneOntologyBiologicalProcessaxonogenesis

SMO ANOS1 CYFIP1 CYFIP2 EPHA4 EPHB1

1.72e-03566476GO:0007409
GeneOntologyBiologicalProcessregulation of glial cell differentiation

GPR37L1 KDM4A EPHA4

1.72e-03104473GO:0045685
GeneOntologyBiologicalProcessresponse to axon injury

KCNB1 AXL EPHA4

1.77e-03105473GO:0048678
GeneOntologyBiologicalProcessprotein autophosphorylation

MAP3K9 MAP3K21 EPHA4 EPHB1

1.79e-03228474GO:0046777
GeneOntologyBiologicalProcessimport across plasma membrane

ABCC9 SLC24A1 SLC24A2 ABCC8

1.85e-03230474GO:0098739
GeneOntologyBiologicalProcesscalcium ion homeostasis

TMEM38A FCRL5 SLC24A1 SLC24A2 CNGB1

1.86e-03389475GO:0055074
GeneOntologyBiologicalProcessneural precursor cell proliferation

GPR37L1 SMO KCNA1 EPHB1

1.93e-03233474GO:0061351
GeneOntologyBiologicalProcessregulation of modification of synaptic structure

CYFIP1 EPHA4

1.98e-0329472GO:1905244
GeneOntologyBiologicalProcessregulation of cysteine-type endopeptidase activity

AIFM1 GRAMD4 RPS6KA1 CYFIP2

2.09e-03238474GO:2000116
GeneOntologyBiologicalProcessregulation of peptidase activity

AIFM1 GRAMD4 RPS6KA1 CYFIP2 EPHA4

2.24e-03406475GO:0052547
GeneOntologyBiologicalProcessregulation of double-strand break repair via nonhomologous end joining

KDM4D KDM4E

2.41e-0332472GO:2001032
GeneOntologyBiologicalProcesscentral nervous system projection neuron axonogenesis

EPHA4 EPHB1

2.41e-0332472GO:0021952
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

KCNA1 GABBR1

2.41e-0332472GO:0099505
GeneOntologyBiologicalProcessneuron apoptotic process

SMO KCNB1 AIFM1 AXL EPHA4

2.41e-03413475GO:0051402
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

TMEM38A FRRS1 FCRL5 SLC24A1 SLC24A2 CNGB1

2.52e-03611476GO:0030003
GeneOntologyBiologicalProcesscell junction disassembly

ABCC8 EPHA4

2.57e-0333472GO:0150146
GeneOntologyBiologicalProcessdicarboxylic acid transport

SLC19A2 ABCC8 GABBR1

2.58e-03120473GO:0006835
GeneOntologyBiologicalProcessneurotrophin TRK receptor signaling pathway

CYFIP1 CYFIP2

2.72e-0334472GO:0048011
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

TMEM38A FRRS1 FCRL5 SLC24A1 SLC24A2 CNGB1

2.76e-03622476GO:0006873
GeneOntologyCellularComponentmonoatomic ion channel complex

PORCN ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB CNGB1 ABCC8 PKD1L1

9.48e-093784710GO:0034702
GeneOntologyCellularComponentcation channel complex

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CNGB1 ABCC8 PKD1L1

4.88e-08235478GO:0034703
GeneOntologyCellularComponentpotassium channel complex

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8

1.19e-07104476GO:0034705
GeneOntologyCellularComponenttransmembrane transporter complex

PORCN ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB CNGB1 ABCC8 PKD1L1

1.99e-075234710GO:1902495
GeneOntologyCellularComponenttransporter complex

PORCN ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB CNGB1 ABCC8 PKD1L1

3.16e-075504710GO:1990351
GeneOntologyCellularComponentpericentric heterochromatin

KDM4D KDM4A KDM4E KDM4B

7.70e-0732474GO:0005721
GeneOntologyCellularComponentpotassium ion-transporting ATPase complex

ABCC9 ABCC8

1.48e-053472GO:0031004
GeneOntologyCellularComponentinward rectifying potassium channel

ABCC9 ABCC8

2.96e-054472GO:0008282
GeneOntologyCellularComponentvoltage-gated potassium channel complex

KCNA1 KCNA6 KCNB2 KCNB1

5.19e-0591474GO:0008076
GeneOntologyCellularComponentciliary membrane

GPR37L1 SMO CNGB1 PKD1L1

6.94e-0598474GO:0060170
GeneOntologyCellularComponentheterochromatin

KDM4D KDM4A KDM4E KDM4B

7.81e-05101474GO:0000792
GeneOntologyCellularComponentaxon terminus

CYFIP1 KCNA1 KCNA6 CNGB1 EPHA4

1.06e-04210475GO:0043679
GeneOntologyCellularComponentpresynapse

SV2C CYFIP1 KCNA1 KCNA6 SLC24A2 CNGB1 ABCC8 GABBR1 EPHA4

1.35e-04886479GO:0098793
GeneOntologyCellularComponentaxon

SMO CYFIP1 KCNA1 KCNA6 KCNB1 CNGB1 GABBR1 EPHA4 EPHB1

1.41e-04891479GO:0030424
GeneOntologyCellularComponentaxonal growth cone

SMO CYFIP1 EPHA4

1.41e-0445473GO:0044295
GeneOntologyCellularComponentneuron projection terminus

CYFIP1 KCNA1 KCNA6 CNGB1 EPHA4

1.73e-04233475GO:0044306
GeneOntologyCellularComponentdendritic growth cone

SMO CYFIP1

3.22e-0412472GO:0044294
GeneOntologyCellularComponentSCAR complex

CYFIP1 CYFIP2

3.22e-0412472GO:0031209
GeneOntologyCellularComponentplasma membrane protein complex

PORCN ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8 GABBR1

3.27e-04785478GO:0098797
GeneOntologyCellularComponentmembrane protein complex

PORCN ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB CNGB1 ABCC8 GABBR1 PKD1L1

3.88e-0414984711GO:0098796
GeneOntologyCellularComponentcell projection membrane

GPR37L1 SMO KCNB1 CNGB1 GABBR1 PKD1L1

3.90e-04431476GO:0031253
GeneOntologyCellularComponentdistal axon

SMO CYFIP1 KCNA1 KCNA6 CNGB1 EPHA4

4.09e-04435476GO:0150034
GeneOntologyCellularComponentneuronal cell body

SMO CYFIP1 KCNA1 KCNB2 KCNB1 SLC24A1 GABBR1 EPHA4

4.94e-04835478GO:0043025
GeneOntologyCellularComponentdendrite

SMO CYFIP1 KCNA1 KCNB2 KCNB1 GABBR1 EPHA4 EPHB1

5.91e-04858478GO:0030425
GeneOntologyCellularComponentdendritic tree

SMO CYFIP1 KCNA1 KCNB2 KCNB1 GABBR1 EPHA4 EPHB1

6.00e-04860478GO:0097447
GeneOntologyCellularComponentdendrite terminus

SMO CYFIP1

9.16e-0420472GO:0044292
GeneOntologyCellularComponentfilopodium tip

CYFIP1 EPHB1

9.16e-0420472GO:0032433
GeneOntologyCellularComponentcell body

SMO CYFIP1 KCNA1 KCNB2 KCNB1 SLC24A1 GABBR1 EPHA4

9.93e-04929478GO:0044297
GeneOntologyCellularComponentsomatodendritic compartment

SMO CYFIP1 KCNA1 KCNB2 KCNB1 SLC24A1 GABBR1 EPHA4 EPHB1

1.45e-031228479GO:0036477
GeneOntologyCellularComponentperikaryon

KCNA1 KCNB2 KCNB1 EPHA4

1.57e-03223474GO:0043204
GeneOntologyCellularComponentfilopodium

CYFIP1 EPHA4 EPHB1

2.67e-03123473GO:0030175
GeneOntologyCellularComponentchromosome, centromeric region

KDM4D KDM4A KDM4E KDM4B

3.40e-03276474GO:0000775
GeneOntologyCellularComponentneuronal cell body membrane

KCNB2 KCNB1

4.21e-0343472GO:0032809
GeneOntologyCellularComponentcell body membrane

KCNB2 KCNB1

5.01e-0347472GO:0044298
GeneOntologyCellularComponentcation-transporting ATPase complex

ABCC9 ABCC8

5.44e-0349472GO:0090533
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ABCC9 ABCC8

6.81e-0355472GO:0098533
GeneOntologyCellularComponentsarcolemma

ABCC9 KCNB1 ABCC8

8.94e-03190473GO:0042383
GeneOntologyCellularComponentreceptor complex

GPR37L1 PORCN FCRL5 AXL GABBR1

9.56e-03581475GO:0043235
GeneOntologyCellularComponentnon-motile cilium

SMO CNGB1 PKD1L1

9.72e-03196473GO:0097730
GeneOntologyCellularComponentcell surface

ANOS1 KCNA1 FCRL5 KCNB1 SLC24A1 AXL EPHA4

1.15e-021111477GO:0009986
GeneOntologyCellularComponentdendritic shaft

GABBR1 EPHA4

1.21e-0274472GO:0043198
DomainJmjN

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

3.80e-1410476PF02375
DomainJmjN

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

3.80e-1410476SM00545
DomainJMJN

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

3.80e-1410476PS51183
DomainJmjN

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

3.80e-1410476IPR003349
DomainJmjC

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

2.37e-1124476PF02373
DomainJMJC

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.57e-1032476PS51184
DomainJmjC_dom

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.57e-1032476IPR003347
DomainJmjC

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.92e-1033476SM00558
DomainK_chnl_volt-dep_Kv

KCNA1 KCNA6 KCNB2 KCNB1

5.92e-0727474IPR003968
DomainVG_K_chnl

KCNA1 KCNA6 KCNB2 KCNB1

1.37e-0633474IPR028325
DomainTyrKc

MAP3K9 MAP3K21 AXL EPHA4 EPHB1

2.72e-0688475SM00219
DomainTyr_kinase_cat_dom

MAP3K9 MAP3K21 AXL EPHA4 EPHB1

2.72e-0688475IPR020635
DomainK_chnl_volt-dep_Kv2

KCNB2 KCNB1

6.20e-062472IPR003973
DomainCytoplasmic_FMR1-int

CYFIP1 CYFIP2

6.20e-062472IPR008081
DomainFragX_IP

CYFIP1 CYFIP2

6.20e-062472PF05994
DomainKv2channel

KCNB2 KCNB1

6.20e-062472PF03521
DomainSulphorea_rcpt

ABCC9 ABCC8

6.20e-062472IPR000388
DomainBTB_2

KCNA1 KCNA6 KCNB2 KCNB1

9.42e-0653474PF02214
DomainT1-type_BTB

KCNA1 KCNA6 KCNB2 KCNB1

9.42e-0653474IPR003131
DomainIon_trans_dom

KCNA1 KCNA6 KCNB2 KCNB1 CNGB1

9.70e-06114475IPR005821
DomainIon_trans

KCNA1 KCNA6 KCNB2 KCNB1 CNGB1

9.70e-06114475PF00520
DomainSer-Thr/Tyr_kinase_cat_dom

MAP3K9 MAP3K21 AXL EPHA4 EPHB1

2.45e-05138475IPR001245
DomainDUF1394

CYFIP1 CYFIP2

3.71e-054472PF07159
DomainLys_sp_deMease-like_dom

KDM5D KDM5C

3.71e-054472IPR013637
DomainDUF1394

CYFIP1 CYFIP2

3.71e-054472IPR009828
DomainMLK1/MLK2/MLK4

MAP3K9 MAP3K21

3.71e-054472IPR016231
DomainPLU-1

KDM5D KDM5C

3.71e-054472PF08429
DomainMAP3K10

MAP3K9 MAP3K21

3.71e-054472IPR015785
DomainProtein_kinase_ATP_BS

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

4.19e-05379477IPR017441
Domainfn3

ANOS1 MID2 AXL EPHA4 EPHB1

5.27e-05162475PF00041
Domainzf-C5HC2

KDM5D KDM5C

6.17e-055472PF02928
DomainK/Na/Ca-exchanger

SLC24A1 SLC24A2

6.17e-055472IPR004481
DomainZnf_C5HC2

KDM5D KDM5C

6.17e-055472IPR004198
DomainPHD

KDM4A KDM5D KDM5C KDM4B

7.35e-0589474SM00249
DomainZnf_PHD

KDM4A KDM5D KDM5C KDM4B

8.01e-0591474IPR001965
DomainZF_PHD_2

KDM4A KDM5D KDM5C KDM4B

9.48e-0595474PS50016
DomainZF_PHD_1

KDM4A KDM5D KDM5C KDM4B

9.87e-0596474PS01359
DomainFN3

ANOS1 MID2 AXL EPHA4 EPHB1

9.89e-05185475SM00060
DomainPROTEIN_KINASE_ATP

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

1.39e-04459477PS00107
DomainFN3

ANOS1 MID2 AXL EPHA4 EPHB1

1.39e-04199475PS50853
DomainK_chnl_volt-dep_Kv1

KCNA1 KCNA6

1.72e-048472IPR003972
DomainFN3_dom

ANOS1 MID2 AXL EPHA4 EPHB1

1.75e-04209475IPR003961
DomainProt_kinase_dom

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

2.05e-04489477IPR000719
DomainPROTEIN_KINASE_DOM

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

2.16e-04493477PS50011
DomainNaCa_Exmemb

SLC24A1 SLC24A2

2.21e-049472IPR004837
DomainNa_Ca_ex

SLC24A1 SLC24A2

2.21e-049472PF01699
DomainPkinase_Tyr

MAP3K21 AXL EPHA4 EPHB1

3.08e-04129474PF07714
DomainKinase-like_dom

MAP3K9 MAP3K21 MAPK13 AXL RPS6KA1 EPHA4 EPHB1

3.83e-04542477IPR011009
DomainChannel_four-helix_dom

KCNA1 KCNA6 KCNB1

3.97e-0457473IPR027359
Domain-

KCNA1 KCNA6 KCNB1

3.97e-04574731.20.120.350
DomainZnf_FYVE_PHD

KDM4A KDM5D KDM5C KDM4B

5.05e-04147474IPR011011
DomainRECEPTOR_TYR_KIN_V_2

EPHA4 EPHB1

5.53e-0414472PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA4 EPHB1

5.53e-0414472PS00790
DomainEphA2_TM

EPHA4 EPHB1

5.53e-0414472PF14575
DomainTyr_kinase_ephrin_rcpt

EPHA4 EPHB1

5.53e-0414472IPR016257
DomainEph_TM

EPHA4 EPHB1

5.53e-0414472IPR027936
DomainEphrin_rcpt_lig-bd_dom

EPHA4 EPHB1

5.53e-0414472IPR001090
DomainTyr_kinase_rcpt_V_CS

EPHA4 EPHB1

5.53e-0414472IPR001426
DomainEPH_LBD

EPHA4 EPHB1

5.53e-0414472PS51550
DomainEPH_lbd

EPHA4 EPHB1

5.53e-0414472SM00615
DomainEphrin_lbd

EPHA4 EPHB1

5.53e-0414472PF01404
Domain-

KDM5D KDM5C

6.37e-04154721.10.150.60
DomainARID

KDM5D KDM5C

6.37e-0415472PF01388
DomainBRIGHT

KDM5D KDM5C

6.37e-0415472SM00501
DomainARID_dom

KDM5D KDM5C

6.37e-0415472IPR001606
DomainARID

KDM5D KDM5C

6.37e-0415472PS51011
DomainPHD

KDM5D KDM5C KDM4B

8.88e-0475473PF00628
DomainBTB

KCNA1 KCNA6 KCNB2 KCNB1

1.08e-03180474SM00225
DomainBTB/POZ_dom

KCNA1 KCNA6 KCNB2 KCNB1

1.19e-03185474IPR000210
DomainSKP1/BTB/POZ

KCNA1 KCNA6 KCNB2 KCNB1

1.29e-03189474IPR011333
DomainEPHD

KDM4A KDM4B

1.39e-0322472PS51805
DomainTUDOR

KDM4A KDM4B

1.52e-0323472PS50304
DomainABC_membrane

ABCC9 ABCC8

1.65e-0324472PF00664
DomainEphrin_rec_like

EPHA4 EPHB1

1.79e-0325472SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHA4 EPHB1

1.79e-0325472IPR011641
DomainPROTEIN_KINASE_TYR

AXL EPHA4 EPHB1

1.87e-0397473PS00109
DomainTyr_kinase_AS

AXL EPHA4 EPHB1

1.87e-0397473IPR008266
DomainS_TKc

MAP3K9 MAP3K21 MAPK13 RPS6KA1 EPHA4

2.02e-03359475SM00220
DomainTUDOR

KDM4A KDM4B

2.09e-0327472SM00333
DomainABC_TM1F

ABCC9 ABCC8

2.25e-0328472PS50929
DomainABC1_TM_dom

ABCC9 ABCC8

2.25e-0328472IPR011527
DomainTudor

KDM4A KDM4B

2.58e-0330472IPR002999
DomainABC_transporter_CS

ABCC9 ABCC8

5.01e-0342472IPR017871
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.15e-1029386MM14934
PathwayREACTOME_POTASSIUM_CHANNELS

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8 GABBR1

6.68e-0998387MM14545
PathwayREACTOME_POTASSIUM_CHANNELS

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8 GABBR1

9.48e-09103387M1073
PathwayREACTOME_HDMS_DEMETHYLATE_HISTONES

KDM4D KDM4A KDM5D KDM5C KDM4B

2.10e-0750385M27232
PathwayREACTOME_NEURONAL_SYSTEM

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8 RPS6KA1 GABBR1

2.46e-06335388MM14503
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNA6 KCNB2 KCNB1

4.23e-0641384MM14546
PathwayREACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS

KCNA1 KCNA6 KCNB2 KCNB1

5.14e-0643384M1056
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

6.67e-06175386MM14941
PathwayREACTOME_NEURONAL_SYSTEM

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8 RPS6KA1 GABBR1

1.11e-05411388M735
PathwayREACTOME_INWARDLY_RECTIFYING_K_CHANNELS

ABCC9 ABCC8 GABBR1

1.11e-0435383M1075
PathwayWP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING

MAP3K9 MAPK13 RPS6KA1

1.21e-0436383M39908
PathwayREACTOME_INWARDLY_RECTIFYING_K_CHANNELS

ABCC9 ABCC8 GABBR1

1.21e-0436383MM14544
PathwayREACTOME_SIGNALING_BY_VEGF

CYFIP1 MAPK13 AXL CYFIP2

1.64e-04103384MM14752
PathwayREACTOME_SIGNALING_BY_VEGF

CYFIP1 MAPK13 AXL CYFIP2

1.83e-04106384M27077
PathwayBIOCARTA_EPHA4_PATHWAY

EPHA4 EPHB1

1.96e-048382M16334
PathwayBIOCARTA_EPHA4_PATHWAY

EPHA4 EPHB1

2.52e-049382MM1388
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC24A1 SLC24A2

3.83e-0411382M27336
PathwayREACTOME_ACTIVATION_OF_THE_PHOTOTRANSDUCTION_CASCADE

SLC24A1 CNGB1

3.83e-0411382M27180
PathwayKEGG_MEDICUS_REFERENCE_MLK_JNK_SIGNALING_PATHWAY

MAP3K9 MAP3K21

4.59e-0412382M47929
PathwayREACTOME_SODIUM_CALCIUM_EXCHANGERS

SLC24A1 SLC24A2

5.42e-0413382MM15078
PathwayREACTOME_CHROMATIN_MODIFYING_ENZYMES

KDM4D KDM4A KDM5D KDM5C KDM4B

7.68e-04272385M29619
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPE_TO_RAC_SIGNALING_PATHWAY

CYFIP1 CYFIP2

1.30e-0320382M47737
PathwayBIOCARTA_MAPK_PATHWAY

MAP3K9 MAPK13 RPS6KA1

1.33e-0381383M13863
PathwayWP_BARDETBIEDL_SYNDROME

SMO CNGB1 PKD1L1

1.69e-0388383M45557
PathwayKEGG_MEDICUS_REFERENCE_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

CYFIP1 CYFIP2

2.04e-0325382M47716
PathwayWP_GPCRS_OTHER

GPR37L1 SMO GABBR1

2.17e-0396383MM15939
PathwayKEGG_MEDICUS_PATHOGEN_SHIGELLA_IPGD_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

CYFIP1 CYFIP2

2.74e-0329382M47717
PathwayREACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES

ANOS1 CYFIP1 MAPK13 AXL RPS6KA1 CYFIP2

2.77e-03532386M27870
PathwayKEGG_MEDICUS_PATHOGEN_SALMONELLA_SOPB_TO_ARNO_ARF_ACTB_G_SIGNALING_PATHWAY

CYFIP1 CYFIP2

2.93e-0330382M47738
Pubmed

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.

KDM4D KDM4A KDM4E KDM4B

1.46e-11547416738407
Pubmed

Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.

KDM4D KDM4A KDM4E KDM4B

1.46e-11547421914792
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

5.85e-114947634368113
Pubmed

Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.

KDM4D KDM4A KDM4E KDM5C KDM4B

7.25e-112147527626377
Pubmed

New nomenclature for chromatin-modifying enzymes.

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

1.51e-105747618022353
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB ABCC8

7.70e-1013947716985003
Pubmed

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.

KDM4D KDM4A KDM4E KDM4B

9.59e-101147419144645
Pubmed

The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice.

KDM4D KDM4A KDM4E

2.31e-09347321555854
Pubmed

K+ current diversity is produced by an extended gene family conserved in Drosophila and mouse.

KCNA1 KCNB2 KCNB1

2.31e-0854732333511
Pubmed

Identification and characterization of JMJD2 family genes in silico.

KDM4D KDM4A KDM4B

4.61e-08647315138608
Pubmed

Pore size matters for potassium channel conductance.

KCNA1 KCNA6 KCNB2

8.06e-08747327619418
Pubmed

Voltage-gated potassium channel genes are clustered in paralogous regions of the mouse genome.

KCNA1 KCNA6 KCNB2 KCNB1

8.97e-08314748034307
Pubmed

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.

KCNA1 KCNA6 KCNB2 KCNB1

2.58e-074047416382104
Pubmed

Developmental expression of voltage-sensitive K+ channels in mouse skeletal muscle and C2C12 cells.

KCNA1 KCNA6 KCNB1

2.76e-07104731383027
Pubmed

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases.

KDM4D KDM4A KDM4B

8.33e-071447316603238
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

GPR37L1 SV2C KCNA1 KCNA6 AIFM1 GABBR1 EPHA4

1.16e-0640547738187761
Pubmed

Alteration of Neuronal Excitability and Short-Term Synaptic Plasticity in the Prefrontal Cortex of a Mouse Model of Mental Illness.

KCNA1 KCNA6 KCNB1

1.28e-061647328283561
Pubmed

Histone Demethylase JMJD2D Interacts With β-Catenin to Induce Transcription and Activate Colorectal Cancer Cell Proliferation and Tumor Growth in Mice.

KDM4D KDM4E

1.79e-06247230472235
Pubmed

Remodeling neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels.

KCNB2 KCNB1

1.79e-06247230091655
Pubmed

Complex consequences of Cantu syndrome SUR2 variant R1154Q in genetically modified mice.

ABCC9 ABCC8

1.79e-06247233529173
Pubmed

Mutations of histone demethylase genes encoded by X and Y chromosomes, Kdm5c and Kdm5d, lead to noncompaction cardiomyopathy in mice.

KDM5D KDM5C

1.79e-06247232081420
Pubmed

Repressive histone methylation regulates cardiac myocyte cell cycle exit.

KDM4D KDM4E

1.79e-06247229800554
Pubmed

Promoter DNA methylation regulates murine SUR1 (Abcc8) and SUR2 (Abcc9) expression in HL-1 cardiomyocytes.

ABCC9 ABCC8

1.79e-06247222844491
Pubmed

Kv2.1 Clustering Contributes to Insulin Exocytosis and Rescues Human β-Cell Dysfunction.

KCNB2 KCNB1

1.79e-06247228607108
Pubmed

Different dysregulations of CYFIP1 and CYFIP2 in distinct types of dementia.

CYFIP1 CYFIP2

1.79e-06247238128786
Pubmed

Analysis of mutation rates in the SMCY/SMCX genes shows that mammalian evolution is male driven.

KDM5D KDM5C

1.79e-0624729060413
Pubmed

Molecular determinants of ATP-sensitive potassium channel MgATPase activity: diabetes risk variants and diazoxide sensitivity.

ABCC9 ABCC8

1.79e-06247226181369
Pubmed

Cytoplasmic FMR1 interacting protein (CYFIP) family members and their function in neural development and disorders.

CYFIP1 CYFIP2

1.79e-06247234327661
Pubmed

Molecular cloning and functional expression of the potassium-dependent sodium-calcium exchanger from human and chicken retinal cone photoreceptors.

SLC24A1 SLC24A2

1.79e-06247210662833
Pubmed

Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling.

KDM4D KDM4E

1.79e-06247235027670
Pubmed

Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons.

KCNB2 KCNB1

1.79e-06247226538660
Pubmed

Embryonic development following somatic cell nuclear transfer impeded by persisting histone methylation.

KDM4D KDM4E

1.79e-06247225417163
Pubmed

Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.

KCNB2 KCNB1

1.79e-06247229403353
Pubmed

Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx.

KDM5D KDM5C

1.79e-06247210441747
Pubmed

Kdm4d mutant mice show impaired sperm motility and subfertility.

KDM4D KDM4E

1.79e-06247239034148
Pubmed

C57BL/6N mutation in cytoplasmic FMRP interacting protein 2 regulates cocaine response.

CYFIP1 CYFIP2

1.79e-06247224357318
Pubmed

Cytoplasmic FMRP interacting protein 1/2 (CYFIP1/2) expression analysis in autism.

CYFIP1 CYFIP2

1.79e-06247229752658
Pubmed

Reader domain specificity and lysine demethylase-4 family function.

KDM4A KDM4B

1.79e-06247227841353
Pubmed

Inefficient purifying selection: the mammalian Y chromosome in the rodent genus Mus.

KDM5D KDM5C

1.79e-06247216416087
Pubmed

Protein interactome and cell-type expression analyses reveal that cytoplasmic FMR1-interacting protein 1 (CYFIP1), but not CYFIP2, associates with astrocytic focal adhesion.

CYFIP1 CYFIP2

1.79e-06247235567753
Pubmed

Cyfip1 Haploinsufficiency Increases Compulsive-Like Behavior and Modulates Palatable Food Intake in Mice: Dependence on Cyfip2 Genetic Background, Parent-of Origin, and Sex.

CYFIP1 CYFIP2

1.79e-06247231324746
Pubmed

Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling.

KDM4D KDM4E

1.79e-06247232094404
Pubmed

A mouse Y chromosome gene encoded by a region essential for spermatogenesis and expression of male-specific minor histocompatibility antigens.

KDM5D KDM5C

1.79e-0624727524912
Pubmed

Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma.

KDM4D KDM4B

1.79e-06247227630312
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MAP3K9 CYFIP1 MAP3K21 MAPK13 AIFM1 AXL RPS6KA1 CYFIP2 EPHA4

3.09e-0691047936736316
Pubmed

The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets.

KCNB2 KCNB1

5.36e-06347223161216
Pubmed

Kv8.1, a new neuronal potassium channel subunit with specific inhibitory properties towards Shab and Shaw channels.

KCNB2 KCNB1

5.36e-0634728670833
Pubmed

Histone demethylase JMJD2D protects against enteric bacterial infection via up-regulating colonic IL-17F to induce β-defensin expression.

KDM4D KDM4E

5.36e-06347238905308
Pubmed

The testis-enriched histone demethylase, KDM4D, regulates methylation of histone H3 lysine 9 during spermatogenesis in the mouse but is dispensable for fertility.

KDM4D KDM4E

5.36e-06347221293030
Pubmed

Functional roles of KATP channel subunits in metabolic inhibition.

ABCC9 ABCC8

5.36e-06347223624089
Pubmed

KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1.

KDM4A KDM4B

5.36e-06347226397136
Pubmed

Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.

KDM4D KDM4A

5.36e-06347217555712
Pubmed

Cloning, sequence and chromosomal localization of MK6, a murine potassium channel gene.

KCNA1 KCNA6

5.36e-0634721285906
Pubmed

Structural analysis of human KDM5B guides histone demethylase inhibitor development.

KDM4A KDM5C

5.36e-06347227214403
Pubmed

Diversity within the JMJD2 histone demethylase family.

KDM4D KDM4A

5.36e-06347217207460
Pubmed

Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.

KDM4A KDM4B

5.36e-06347217611647
Pubmed

Clinical spectrum of voltage-gated potassium channel autoimmunity.

KCNA1 KCNA6

5.36e-06347218474843
Pubmed

Seizures and reduced life span in mice lacking the potassium channel subunit Kv1.2, but hypoexcitability and enlarged Kv1 currents in auditory neurons.

KCNA1 KCNA6

5.36e-06347217634333
Pubmed

Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.

KDM4A KDM4B

5.36e-06347227266524
Pubmed

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.

KDM4A KDM4B

5.36e-06347231434704
Pubmed

Characterization of a voltage-activated K-channel gene cluster on human chromosome 12p13.

KCNA1 KCNA6

5.36e-0634728821794
Pubmed

Identification of a mouse male-specific transplantation antigen, H-Y.

KDM5D KDM5C

5.36e-0634727544442
Pubmed

FGL1: a novel biomarker and target for non-small cell lung cancer, promoting tumor progression and metastasis through KDM4A/STAT3 transcription mechanism.

KDM4A FGL1

5.36e-06347239085849
Pubmed

A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease.

SLC24A1 CNGB1

5.36e-06347226246500
Pubmed

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.

ABCC9 ABCC8

5.36e-0634728630239
Pubmed

Expression and function of K(V)2-containing channels in human urinary bladder smooth muscle.

KCNB2 KCNB1

5.36e-06347222422395
Pubmed

Differential expressions of the eph family of receptor tyrosine kinase genes (sek, elk, eck) in the developing nervous system of the mouse.

EPHA4 EPHB1

5.36e-0634727609620
Pubmed

The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development.

KDM4A KDM4B

5.36e-06347219696013
Pubmed

Chromosomal mapping in the mouse of eight K(+)-channel genes representing the four Shaker-like subfamilies Shaker, Shab, Shaw, and Shal.

KCNA1 KCNA6 KCNB1

5.88e-06264737905852
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

MAP3K9 KCNA6 AXL RPS6KA1 EPHA4 EPHB1

1.07e-0537247622939624
Pubmed

Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development.

CYFIP1 CYFIP2

1.07e-05447215294869
Pubmed

Novel JARID1C/SMCX mutations in patients with X-linked mental retardation.

KDM5D KDM5C

1.07e-05447216541399
Pubmed

Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium.

ABCC9 ABCC8

1.07e-05447212356945
Pubmed

Identification of VAPA and VAPB as Kv2 Channel-Interacting Proteins Defining Endoplasmic Reticulum-Plasma Membrane Junctions in Mammalian Brain Neurons.

KCNB2 KCNB1

1.07e-05447230012696
Pubmed

Histone demethylase KDM4D cooperates with NFIB and MLL1 complex to regulate adipogenic differentiation of C3H10T1/2 mesenchymal stem cells.

KDM4D KDM4E

1.07e-05447232080306
Pubmed

Cation dependencies and turnover rates of the human K⁺-dependent Na⁺-Ca²⁺ exchangers NCKX1, NCKX2, NCKX3 and NCKX4.

SLC24A1 SLC24A2

1.07e-05447226631410
Pubmed

Retrolinkin recruits the WAVE1 protein complex to facilitate BDNF-induced TrkB endocytosis and dendrite outgrowth.

CYFIP1 CYFIP2

1.07e-05447227605705
Pubmed

Protein complexes containing CYFIP/Sra/PIR121 coordinate Arf1 and Rac1 signalling during clathrin-AP-1-coated carrier biogenesis at the TGN.

CYFIP1 CYFIP2

1.07e-05447220228810
Pubmed

Effects of altered ephrin-A5 and EphA4/EphA7 expression on tumor growth in a medulloblastoma mouse model.

SMO EPHA4

1.07e-05447226345456
Pubmed

X- and Y-Linked Chromatin-Modifying Genes as Regulators of Sex-Specific Cancer Incidence and Prognosis.

KDM5D KDM5C

1.07e-05447232732223
Pubmed

TRIM14 inhibits OPTN-mediated autophagic degradation of KDM4D to epigenetically regulate inflammation.

KDM4D KDM4E

1.07e-05447235145029
Pubmed

Assembly limits the pharmacological complexity of ATP-sensitive potassium channels.

ABCC9 ABCC8

1.07e-05447211825905
Pubmed

The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.

KDM4A KDM4B

1.07e-05447231014673
Pubmed

Isolation and characterization of rat skeletal muscle and cytoplasmic actin genes.

KDM4D KDM4E

1.07e-0544726953429
Pubmed

A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human.

KDM5D KDM5C

1.07e-0544727951230
Pubmed

Expression of ATP-sensitive K+ channel subunits during perinatal maturation in the mouse heart.

ABCC9 ABCC8

1.07e-05447216085792
Pubmed

Alternative sulfonylurea receptor expression defines metabolic sensitivity of K-ATP channels in dopaminergic midbrain neurons.

ABCC9 ABCC8

1.07e-05447210022826
Pubmed

The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

KDM5D KDM5C

1.07e-05447217320160
Pubmed

Conserved functional consequences of disease-associated mutations in the slide helix of Kir6.1 and Kir6.2 subunits of the ATP-sensitive potassium channel.

ABCC9 ABCC8

1.07e-05447228842488
Pubmed

Signaling by ephrinB1 and Eph kinases in platelets promotes Rap1 activation, platelet adhesion, and aggregation via effector pathways that do not require phosphorylation of ephrinB1.

EPHA4 EPHB1

1.07e-05447214576067
Pubmed

Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.

KDM4A KDM4B

1.07e-05447227257215
Pubmed

A novel sulfonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel.

ABCC9 ABCC8

1.07e-0544728798681
Pubmed

Distinct cellular expression and subcellular localization of Kv2 voltage-gated K+ channel subtypes in dorsal root ganglion neurons conserved between mice and humans.

KCNB2 KCNB1

1.07e-05447238335058
Pubmed

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

KDM4A KDM5D KDM5C

1.23e-053347326864203
Pubmed

Ion channel expression in the developing enteric nervous system.

KCNA1 KCNA6 KCNB1

1.74e-053747325798587
Pubmed

Kv2 channel-AMIGO β-subunit assembly modulates both channel function and cell adhesion molecule surface trafficking.

KCNB2 KCNB1

1.78e-05547234137443
Pubmed

Mutation of histidine 105 in the T1 domain of the potassium channel Kv2.1 disrupts heteromerization with Kv6.3 and Kv6.4.

KCNB2 KCNB1

1.78e-05547219074135
Pubmed

Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.

KCNA1 KCNA6

1.78e-05547221233214
Pubmed

Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred.

EPHA4 EPHB1

1.78e-05547212084815
Pubmed

Expression of potassium-dependent sodium-calcium exchanger in the murine lens.

SLC24A1 SLC24A2

1.78e-05547229128492
InteractionKCNB1 interactions

CYFIP1 KCNA1 KCNB2 KCNB1

2.51e-0643454int:KCNB1
InteractionKCNG4 interactions

KCNB2 KCNB1 AXL

8.29e-0618453int:KCNG4
InteractionSSTR3 interactions

GPR37L1 SV2C KCNA1 KCNA6 AIFM1 GABBR1 EPHA4

2.44e-05393457int:SSTR3
Cytoband6p21.31

MAPK13 GABBR1

8.20e-04414726p21.31
Cytoband11q21

KDM4D KDM4E

9.44e-044447211q21
CytobandEnsembl 112 genes in cytogenetic band chr11q21

KDM4D KDM4E

1.93e-0363472chr11q21
GeneFamilyPHD finger proteins|Lysine demethylases

KDM4D KDM4A KDM5D KDM4E KDM5C KDM4B

6.29e-1224376485
GeneFamilyPotassium voltage-gated channels

KCNA1 KCNA6 KCNB2 KCNB1

1.29e-0640374274
GeneFamilyFibronectin type III domain containing

ANOS1 MID2 AXL EPHA4 EPHB1

1.77e-05160375555
GeneFamilyATP binding cassette subfamily C

ABCC9 ABCC8

3.13e-0413372807
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA4 EPHB1

3.65e-04143721095
GeneFamilyAT-rich interaction domain containing

KDM5D KDM5C

4.21e-0415372418
GeneFamilyMitogen-activated protein kinase kinase kinases|RAF family

MAP3K9 MAP3K21

1.09e-0324372654
GeneFamilyTudor domain containing

KDM4A KDM4B

2.59e-0337372780
GeneFamilyX-linked mental retardation|Angiotensin receptors

MID2 KDM5C

5.26e-0353372103
GeneFamilyG protein-coupled receptors, Class A orphans

GPR37L1 GPR148

1.11e-0278372262
GeneFamilySterile alpha motif domain containing

EPHA4 EPHB1

1.40e-0288372760
GeneFamilyPHD finger proteins

KDM5D KDM5C

1.46e-029037288
CoexpressionGSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP

CRYBG1 FRRS1 CYFIP1 GABBR1 CYFIP2

1.62e-05181465M6323
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 KCNA6 MID2 ABCC8 GABBR1 CYFIP2

6.60e-08200476ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCelldroplet-Heart-4Chambers-21m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 FGL1 KCNA6 MAPK13

1.41e-06183475a046b569bc10083d471b420eb2c6fee93437602d
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 FGL1 KCNA6 MAPK13

1.41e-061834754de2082dca2569d3aac3c9b466f27971c82d302b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5D KCNB1 SLC24A2 ABCC8 CYFIP2

1.92e-061954753e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5D KCNB1 SLC24A2 ABCC8 CYFIP2

1.92e-061954757796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellfacs-Brain_Non-Myeloid-Cortex|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNA1 KCNA6 SLC24A2 GABBR1 EPHB1

1.97e-06196475256fe9bc0815f66a9afe11ba3507ef1372b52fd3
ToppCellP15-Epithelial-epithelial_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

GPR37L1 MAP3K9 KCNA1 KCNA6

1.99e-0515247400d5503d462cfa009fb4cac79ecee11725a18b9a
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SV2C FRRS1 MAPK13 CYFIP2

3.02e-05169474bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 KCNB1

3.46e-05175474c1e082538f31b5c98ac63f71dcca4a1211a14708
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 KCNB1

3.46e-05175474c36b4526970db9ccfbe2c70b00961fab9f13b133
ToppCellfacs-Mammary_Gland-Mammary_Gland-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 KCNB1

3.46e-051754742f9b5bdf8a62e8e99d1c4f677a8e5525bfd3b4ce
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCRL5 KCNB1 ABCC8 EPHA4

3.86e-05180474423454e3390080ae03bb3cbb267255ebfe4df080
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 SV2C KCNA1 KCNA6

3.86e-05180474da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 SV2C KCNA1 KCNA6

3.86e-051804745b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 SV2C KCNA1 KCNA6

3.86e-0518047450758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCRL5 KCNB1 ABCC8 EPHA4

3.86e-05180474dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 AXL

3.95e-051814740b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 SLC24A2

4.48e-0518747416e55d802fc4e71878305e61ad03806aabd59537
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNB1 SLC24A2 ABCC8 CYFIP2

4.58e-05188474a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 ABCC9 KCNA1 SLC24A2

4.67e-05189474a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 ABCC9 KCNA1 SLC24A2

4.67e-05189474302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

SLC19A2 CLCNKB KDM4B CYFIP2

4.67e-05189474a48df46274d51e84ffb40264646de7346104efb9
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 ABCC9 KCNA1 SLC24A2

4.67e-05189474381058f55908f84375b54601d617389ef43ab855
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 SLC24A2

4.77e-05190474ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR37L1 KCNA1 KCNA6 SLC24A2

4.77e-051904744971857eac9af17d66d673ed2ab7072639f60a10
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANOS1 KCNB1 AXL ABCC8

4.97e-05192474b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANOS1 KCNB1 AXL ABCC8

4.97e-05192474bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 ABCC8 GABBR1 CYFIP2

5.71e-05199474333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GPR37L1 ABCC8 GABBR1 CYFIP2

5.71e-05199474e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ComputationalPorins / transporters.

KCNA1 KCNA6 KCNB2 CLCNKB AXL EPHA4 EPHB1

1.79e-06211317MODULE_63
ComputationalIon channels.

KCNA1 KCNA6 KCNB2 CLCNKB

4.54e-0570314MODULE_316
ComputationalRTK signaling.

AXL EPHA4 EPHB1

3.03e-0446313MODULE_259
ComputationalGenes in the cancer module 85.

AXL EPHA4 EPHB1

4.12e-0451313MODULE_85
ComputationalGenes in the cancer module 199.

AXL EPHA4 EPHB1

5.72e-0457313MODULE_199
DrugCID10948590

KCNA1 KCNA6 KCNB2

1.64e-076473CID010948590
DrugAC1Q646P

KCNA1 KCNA6 KCNB2 KCNB1

2.66e-0647474CID000005673
Drugs-nitrosodithiothreitol

KCNA1 KCNB1

4.17e-062472CID000194511
DrugE 4031

KCNA1 KCNA6 KCNB2 KCNB1

4.67e-0654474CID000003184
Drugpotassium

SV2C ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 SLC24A1 CLCNKB SLC24A2 CNGB1 ABCC8

4.88e-0610084711CID000000813
Drugtetrapentylammonium

KCNA1 KCNA6 KCNB2

5.49e-0617473CID000017248
Drugdiazoxide

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 ABCC8

7.02e-06227476CID000003019
Druglanthanum

SMO KCNA1 SLC24A2 AIFM1 KDM5C

8.86e-06136475CID000023926
Drugglibenclamide

ABCC9 KCNA1 KCNA6 KCNB2 KCNB1 CLCNKB ABCC8

1.25e-05382477CID000003488
Drugsotalol

KCNA1 KCNA6 KCNB2 KCNB1

1.56e-0573474CID000005253
DrugVX-745

MAPK13 EPHA4 EPHB1

1.84e-0525473CID003038525
DrugAC1L1B9H

KCNA1 KCNA6 KCNB2 KCNB1

2.03e-0578474CID000001341
Drug4-NA

SLC24A1 SLC24A2

2.50e-054472CID006102690
DrugDiazoxide

ABCC9 AIFM1 ABCC8

2.60e-0528473ctd:D003981
Drugthioformamide

ABCC9 ABCC8

4.15e-055472CID003005587
Drugchromanol 293B

KCNA1 KCNB1 ABCC8

4.31e-0533473CID000121846
Drug4-chromanol

KCNA1 KCNB1 ABCC8

5.15e-0535473CID000092890
DrugMorantel tartrate [26155-31-7]; Up 200; 10.8uM; PC3; HT_HG-U133A

ANOS1 FGL1 GRAMD4 KDM5C CYFIP2

5.52e-051994757250_UP
Drugpyraclofos

KCNA1 KCNA6 KCNB2 KCNB1

6.79e-05106474CID000093460
Drug11-[(2S,3R)-3-amyloxiran-2-yl]undecanoic acid

PORCN KCNA1 AIFM1

7.15e-0539473CID011022912
DrugMnTMPyP

MAPK13 AIFM1 ABCC8

7.15e-0539473CID000004233
DrugGlyburide

ABCC9 ABCC8

1.16e-048472DB01016
DrugNSC-333493

KCNB1 ABCC8

1.49e-049472CID000100083
Diseasechromosome 15q11.2 deletion syndrome (implicated_via_orthology)

CYFIP1 CYFIP2

6.51e-063442DOID:0060393 (implicated_via_orthology)
Diseasesyndromic X-linked intellectual disability Claes-Jensen type (implicated_via_orthology)

KDM5D KDM5C

1.30e-054442DOID:0060809 (implicated_via_orthology)
DiseaseGastric Adenocarcinoma

MAP3K9 AXL EPHB1

4.20e-0545443C0278701
Diseasestomach cancer (is_marker_for)

SMO KDM5C KDM4B EPHB1

6.01e-05142444DOID:10534 (is_marker_for)
Diseasecardiovascular measurement, left ventricular function

KCNB2 EPHA4

6.05e-058442EFO_0004295, EFO_0004298
Diseasealopecia areata (is_marker_for)

KDM4A KDM4B

9.71e-0510442DOID:986 (is_marker_for)
Diseasecolorectal health

KCNB2 KCNB1 PKD1L1 EPHA4

2.29e-04201444EFO_0008460
Diseasesyndromic intellectual disability (implicated_via_orthology)

KDM5D KDM5C

2.57e-0416442DOID:0050888 (implicated_via_orthology)
Diseasevisual epilepsy (biomarker_via_orthology)

SMO ABCC8 GABBR1

3.32e-0490443DOID:11832 (biomarker_via_orthology)
Diseasemelanoma

MAP3K9 CRYBG1 KDM4A KDM4B

5.08e-04248444C0025202
DiseaseNeonatal diabetes mellitus

SLC19A2 ABCC8

6.38e-0425442C0158981
DiseaseParkinsonism (biomarker_via_orthology)

ABCC9 ABCC8

1.18e-0334442DOID:0080855 (biomarker_via_orthology)
Diseasevisual epilepsy (implicated_via_orthology)

KCNA1 GABBR1

1.18e-0334442DOID:11832 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GAAKPYWHQSMFWSD

AIFM1

471

O95831
IAFTVYMNAVWHGWA

GRAMD4

236

Q6IC98
ATYWWMNTLIISAHK

ABCC9

226

O60706
WSVGGFTATWATMTY

ABHD16B

246

Q9H3Z7
LSQWSAHVMEVYSWK

CYFIP1

401

Q7L576
FTSASDVWSYGIVMW

EPHB1

801

P54762
HHYKVFWSWMVSSKS

ANOS1

326

P23352
DAFWWAVVSMTTVGY

KCNA1

361

Q09470
FSYLMVWWAHQVGET

SLC24A1

951

O60721
LGYGSMFTKIWWVHT

GABBR1

676

Q9UBS5
WLYVGMVFSAFCWHI

KDM5D

491

Q9BY66
FTSASDVWSYGIVMW

EPHA4

801

P54764
WSKDSGFYWCKAATM

FCRL5

251

Q96RD9
TISWWGCYSQMFFMH

OR4K13

91

Q8NH42
LYFGMWKTSFAWHTE

KDM4A

176

O75164
YLYFGMWKTTFAWHT

KDM4B

176

O94953
YFGMWKTTFAWHTED

KDM4D

181

Q6B0I6
YLYFGMWKTTFAWHT

KDM4E

176

B2RXH2
SWMHYNQTVDIWSVG

MAPK13

196

O15264
SKWSAHVMEVYSWKL

CYFIP2

401

Q96F07
GMAYTVHKWSELSWA

PORCN

431

Q9H237
DAFWWAVVTMTTVGY

KCNA6

411

P17658
ASFWWATITMTTVGY

KCNB1

366

Q14721
SFWWATITMTTVGYG

KCNB2

371

Q92953
YTWHGWWYSLKSVVM

FGL1

286

Q08830
SWKTYAMTGFVAWHV

FRRS1

511

Q6ZNA5
VMCIVWHSYYLKSAW

GPR37L1

151

O60883
YLSFMSHGAAWKAVA

GPR148

156

Q8TDV2
TCSMKVHWGTWLIYE

CRYBG1

1156

Q9Y4K1
VGYIKISWSTWGEMT

SLC19A2

351

O60779
VGDSQAWHSMTVWYK

PKD1L1

491

Q8TDX9
WHRTTKMSAAGTYAW

MAP3K9

301

P80192
MAWAIIPHYGWSFSM

SV2C

296

Q496J9
WVVGWIQACSHMEFY

FAM78A

86

Q5JUQ0
WHRTTKMSTAGTYAW

MAP3K21

296

Q5TCX8
AVFSYLMVWWAHQVG

SLC24A2

511

Q9UI40
SKGTYWWMNAFIKTA

ABCC8

226

Q09428
RVKTWYEYTWHSQGM

CNGB1

916

Q14028
VMSSHFSVWDYWRGF

CLCNKB

226

P51801
WFVKAGGVAMYAVSW

TLCD5

191

Q6ZRR5
YTSKSDVWSFGVTMW

AXL

726

P30530
MAGVVWFVVLTYAWH

SMO

326

Q99835
VMGWIKYQGVSHFEW

TMEM174

56

Q8WUU8
HYWEVVMGSSTWYAI

MID2

591

Q9UJV3
YHHGWFVMIATGWVK

TMEM38A

141

Q9H6F2
WLYVGMVFSAFCWHI

KDM5C

501

P41229
HSADWWSYGVLMFEM

RPS6KA1

241

Q15418