Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

NUCB2 OBSCN ARHGAP35 DENND11 IQGAP1 SYNGAP1 CCDC88C ARHGAP5 ASAP2 ARHGEF1 EIF5 USP6NL PLCE1

1.80e-0550712513GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

NUCB2 OBSCN ARHGAP35 DENND11 IQGAP1 SYNGAP1 CCDC88C ARHGAP5 ASAP2 ARHGEF1 EIF5 USP6NL PLCE1

1.80e-0550712513GO:0030695
GeneOntologyMolecularFunctionNACHT domain binding

TRIM16 TRIM16L

1.16e-0431252GO:0032089
GeneOntologyMolecularFunctionATP-dependent activity

DHX16 KIF21B MRE11 MYH2 DDX12P ATP10B KIF24 ATAD3B SMARCA2 SMARCA4 DNAH5 SMC1B HELLS

1.27e-0461412513GO:0140657
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRIN2B GRM5

2.31e-0441252GO:0099583
GeneOntologyMolecularFunctiontranslation initiation factor activity

EIF3CL EIF5 EIF3A EIF3C

2.91e-04511254GO:0003743
GeneOntologyMolecularFunctionGTPase activator activity

ARHGAP35 IQGAP1 SYNGAP1 ARHGAP5 ASAP2 ARHGEF1 EIF5 USP6NL

3.77e-042791258GO:0005096
GeneOntologyMolecularFunctionhelicase activity

DHX16 MRE11 DDX12P SMARCA2 SMARCA4 HELLS

4.82e-041581256GO:0004386
GeneOntologyBiologicalProcessformation of cytoplasmic translation initiation complex

EIF3CL EIF5 EIF3A EIF3C

1.32e-06151184GO:0001732
GeneOntologyBiologicalProcesssister chromatid cohesion

MRE11 DDX12P SLF1 BUB1 SMC1B

4.09e-05671185GO:0007062
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex, eIF3m

EIF3CL EIF3A EIF3C

1.63e-0591233GO:0071541
GeneOntologyCellularComponentmicrotubule organizing center

DDX12P SLF1 CCDC146 UBR4 CC2D1A SFI1 ARHGAP35 KMT2E MAP10 KIF24 CCDC88C ODF2L FAM161A RTRAF CCDC15 CENATAC

9.84e-0591912316GO:0005815
GeneOntologyCellularComponenteukaryotic translation initiation factor 3 complex

EIF3CL EIF3A EIF3C

1.05e-04161233GO:0005852
GeneOntologyCellularComponenteukaryotic 48S preinitiation complex

EIF3CL EIF3A EIF3C

1.52e-04181233GO:0033290
GeneOntologyCellularComponentcentrosome

DDX12P SLF1 CCDC146 UBR4 CC2D1A KMT2E MAP10 KIF24 CCDC88C ODF2L FAM161A RTRAF CCDC15 CENATAC

1.77e-0477012314GO:0005813
GeneOntologyCellularComponenteukaryotic 43S preinitiation complex

EIF3CL EIF3A EIF3C

1.80e-04191233GO:0016282
GeneOntologyCellularComponenttranslation preinitiation complex

EIF3CL EIF3A EIF3C

2.11e-04201233GO:0070993
GeneOntologyCellularComponenteuchromatin

KMT2E CTR9 SMARCA4 ELL

8.62e-04721234GO:0000791
GeneOntologyCellularComponentlate endosome

ANXA6 ATP10B GRIN2B PLEKHM1 STEAP3 TMEM192 NBR1 VTI1B

1.07e-033481238GO:0005770
DomainP-loop_NTPase

DHX16 KIF21B MYH2 ARHGAP35 KIF24 IQGAP1 ARHGAP5 ATAD3B TJP1 SMARCA2 SMARCA4 GNAL GNAS DSEL DNAH5 SMC1B TJP3 HELLS

1.24e-0584812418IPR027417
DomainGprotein_alpha_S

GNAL GNAS

4.37e-0521242IPR000367
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

4.37e-0521242IPR014978
DomainSnAC

SMARCA2 SMARCA4

4.37e-0521242PF14619
DomainQLQ

SMARCA2 SMARCA4

4.37e-0521242SM00951
DomainRhoGAP-FF1

ARHGAP35 ARHGAP5

4.37e-0521242PF16512
DomainRhoGAP-FF1

ARHGAP35 ARHGAP5

4.37e-0521242IPR032835
DomainQLQ

SMARCA2 SMARCA4

4.37e-0521242PS51666
DomainEIF3C_N_dom

EIF3CL EIF3C

4.37e-0521242IPR008905
DomaineIF-3c_N

EIF3CL EIF3C

4.37e-0521242PF05470
DomainSnAC

SMARCA2 SMARCA4

4.37e-0521242SM01314
DomainSnAC

SMARCA2 SMARCA4

4.37e-0521242IPR029295
DomainQLQ

SMARCA2 SMARCA4

4.37e-0521242PF08880
DomainEIF3C

EIF3CL EIF3C

4.37e-0521242IPR027516
DomainZO

TJP1 TJP3

1.31e-0431242IPR005417
DomainPINT

EIF3CL EIF3A EIF3C

1.50e-04161243SM00088
DomainPCI_dom

EIF3CL EIF3A EIF3C

1.81e-04171243IPR000717
DomainPCI

EIF3CL EIF3A EIF3C

1.81e-04171243PF01399
DomainHSA

SMARCA2 SMARCA4

2.60e-0441242SM00573
DomainHSA

SMARCA2 SMARCA4

2.60e-0441242PS51204
DomainHSA_dom

SMARCA2 SMARCA4

2.60e-0441242IPR014012
DomainHSA

SMARCA2 SMARCA4

2.60e-0441242PF07529
Domain-

DHX16 ARHGAP35 ARHGAP5 ATAD3B TJP1 SMARCA2 SMARCA4 GNAL GNAS DSEL DNAH5 SMC1B TJP3 HELLS

4.35e-04746124143.40.50.300
DomainBRK

SMARCA2 SMARCA4

6.45e-0461242SM00592
DomainFF_domain

ARHGAP35 ARHGAP5

6.45e-0461242IPR002713
DomainBRK_domain

SMARCA2 SMARCA4

6.45e-0461242IPR006576
DomainFF

ARHGAP35 ARHGAP5

6.45e-0461242PS51676
DomainFF

ARHGAP35 ARHGAP5

6.45e-0461242PF01846
DomainFF

ARHGAP35 ARHGAP5

6.45e-0461242SM00441
DomainBRK

SMARCA2 SMARCA4

6.45e-0461242PF07533
DomainSNF2_N

SMARCA2 SMARCA4 HELLS

1.23e-03321243IPR000330
DomainSNF2_N

SMARCA2 SMARCA4 HELLS

1.23e-03321243PF00176
DomainC2

CC2D1A SYNGAP1 WWC2 SYT5 PLCE1

2.58e-031421245PS50004
DomainRho_GTPase_activation_prot

ARHGAP35 IQGAP1 SYNGAP1 ARHGAP5

2.81e-03881244IPR008936
Domain-

CC2D1A SYNGAP1 WWC2 SYT5 PLCE1

3.09e-0314812452.60.40.150
DomainWD40_repeat_dom

KIF21B KNTC1 UBR4 LYST WDR87 WDR89 TAF5

3.71e-032971247IPR017986
DomainWW

IQGAP1 WWC2 UTRN

3.74e-03471243PF00397
DomainRasGAP

IQGAP1 SYNGAP1

3.78e-03141242SM00323
DomainNPIP

NPIPB8 NPIPB6

3.78e-03141242IPR009443
DomainRasGAP_CS

IQGAP1 SYNGAP1

3.78e-03141242IPR023152
DomainWW

IQGAP1 WWC2 UTRN

3.97e-03481243SM00456
DomainRasGAP

IQGAP1 SYNGAP1

4.34e-03151242PF00616
DomainRAS_GTPASE_ACTIV_1

IQGAP1 SYNGAP1

4.34e-03151242PS00509
DomainRAS_GTPASE_ACTIV_2

IQGAP1 SYNGAP1

4.34e-03151242PS50018
DomainWW_DOMAIN_1

IQGAP1 WWC2 UTRN

4.72e-03511243PS01159
DomainWW_DOMAIN_2

IQGAP1 WWC2 UTRN

4.72e-03511243PS50020
DomainC2_dom

CC2D1A SYNGAP1 WWC2 SYT5 PLCE1

4.78e-031641245IPR000008
DomainGproteinA_insert

GNAL GNAS

4.94e-03161242IPR011025
Domain-

GNAL GNAS

4.94e-031612421.10.400.10
DomainG-alpha

GNAL GNAS

4.94e-03161242PF00503
Domain-

IQGAP1 SYNGAP1

4.94e-031612421.10.506.10
DomainG_alpha

GNAL GNAS

4.94e-03161242SM00275
DomainWW_dom

IQGAP1 WWC2 UTRN

4.98e-03521243IPR001202
DomainGprotein_alpha_su

GNAL GNAS

5.57e-03171242IPR001019
DomainHelicase_C

DHX16 SMARCA2 SMARCA4 HELLS

5.64e-031071244PF00271
DomainHELICc

DHX16 SMARCA2 SMARCA4 HELLS

5.64e-031071244SM00490
DomainHelicase_C

DHX16 SMARCA2 SMARCA4 HELLS

5.83e-031081244IPR001650
DomainHELICASE_CTER

DHX16 SMARCA2 SMARCA4 HELLS

6.02e-031091244PS51194
DomainHELICASE_ATP_BIND_1

DHX16 SMARCA2 SMARCA4 HELLS

6.02e-031091244PS51192
DomainDEXDc

DHX16 SMARCA2 SMARCA4 HELLS

6.02e-031091244SM00487
DomainHelicase_ATP-bd

DHX16 SMARCA2 SMARCA4 HELLS

6.22e-031101244IPR014001
DomainZF_ZZ_2

UTRN NBR1

6.24e-03181242PS50135
DomainZF_ZZ_1

UTRN NBR1

6.24e-03181242PS01357
DomainZZ

UTRN NBR1

6.24e-03181242PF00569
DomainRasGAP_dom

IQGAP1 SYNGAP1

6.24e-03181242IPR001936
PathwayREACTOME_RHOQ_GTPASE_CYCLE

OBSCN ARHGAP35 IQGAP1 ARHGAP5 STEAP3

3.51e-0558915MM15602
PathwayREACTOME_RHOQ_GTPASE_CYCLE

OBSCN ARHGAP35 IQGAP1 ARHGAP5 STEAP3

3.82e-0559915M41812
PathwayWP_NSP1_FROM_SARSCOV2_INHIBITS_TRANSLATION_INITIATION_IN_THE_HOST_CELL

EIF5 EIF3A EIF3C

1.37e-0416913M40040
PathwayREACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS

ELOA2 POLR2B CTR9 TAF5 ELL

1.75e-0481915M865
PathwayREACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS

ELOA2 POLR2B CTR9 TAF5 ELL

1.96e-0483915MM15314
PathwayPID_RHOA_REG_PATHWAY

OBSCN ARHGAP35 ARHGAP5 ARHGEF1

2.16e-0446914M68
PathwayWP_RETT_SYNDROME

GRIN2B SYNGAP1 SMARCA2 SMARCA4

2.54e-0448914M39759
PathwayWP_TRANSLATION_FACTORS

EIF3CL EIF5 EIF3A EIF3C

3.22e-0451914MM15881
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 DHX16 KNTC1 MRE11 ANXA6 POLR2B UBR4 IDH2 NSUN2 IQGAP1 EIF3CL CTR9 CSNK2A2 RTRAF EIF5 SMARCA4 EIF3A EIF3C GNAS ITM2B DNAH5 NBR1 HELLS

2.68e-0914251292330948266
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

KNTC1 MRE11 ZNF141 DCPS ANXA6 BEND3 CC2D1A NSUN2 INO80D IQGAP1 RLF TAOK3 CTR9 CSNK2A2 RTRAF EIF5 SMARCA2 SMARCA4 HELLS

2.74e-0811031291934189442
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

FAM120B GRIN2B IDH2 ARHGAP35 GRM5 NDUFB9 IQGAP1 EIF3CL SYNGAP1 ARHGAP5 ATAD3B TJP1 ARHGEF1 CSNK2A2 RTRAF SMARCA4 LSAMP EIF3A EIF3C UTRN

3.34e-0714311292037142655
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

GRIN2B GRM5 IQGAP1 SYNGAP1 ATAD3B ASAP2 KCNA4 CSNK2A2 GNAS

1.14e-06281129928706196
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

DHX16 KNTC1 NSUN2 KIF24 IQGAP1 EIF3CL ODF2L ATAD3B TJP1 BUB1 SMARCA2 SMARCA4 CCDC15 EIF3A GNAL EIF3C GNAS

1.39e-0611551291720360068
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

MYH2 ANKRD36C DENND11 LYST EIF3CL TRIM16 TAOK3 CTR9 CSNK2A2 NRK BUB1 ANKRD36 EIF3C UTRN CNN1

1.54e-069101291536736316
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

POLR2B NSUN2 IQGAP1 TJP1 RTRAF SMARCA2 SMARCA4 WDR89 EIF3A EIF3C GNAS USP6NL

3.36e-066151291231048545
Pubmed

The pleiotropic mouse phenotype extra-toes spotting is caused by translation initiation factor Eif3c mutations and is associated with disrupted sonic hedgehog signaling.

EIF3CL EIF3A EIF3C

4.12e-069129321292980
Pubmed

The m subunit of murine translation initiation factor eIF3 maintains the integrity of the eIF3 complex and is required for embryonic development, homeostasis, and organ size control.

EIF3CL EIF3A EIF3C

4.12e-069129324003236
Pubmed

Human transcription factor protein interaction networks.

MRE11 SLF1 UBR4 BEND3 CC2D1A NSUN2 INO80D RLF ATAD3B CCDC59 CSNK2A2 NFYA SMARCA2 SMARCA4 EIF3A EIF3C TAF5 HELLS

5.84e-0614291291835140242
Pubmed

Conservation and diversity of eukaryotic translation initiation factor eIF3.

EIF3CL EIF3A EIF3C

5.87e-061012938995409
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

DHX16 MRE11 ANXA6 UBR4 BEND3 NSUN2 IQGAP1 TJP1 CSNK2A2 SMARCA2 SMARCA4 UTRN

6.16e-066531291222586326
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

DHX16 MRE11 ARHGAP35 NSUN2 IQGAP1 EIF3CL TRIM16 WWC2 CTR9 CSNK2A2 SMARCA2 SMARCA4 EIF3C

6.55e-067741291315302935
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

UBR4 IDH2 IQGAP1 EIF3CL ATAD3B CTR9 ARHGEF1 CSNK2A2 SMARCA4 EIF3A EIF3C GNAS

7.40e-066651291230457570
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

KNTC1 MRE11 DCPS ANXA6 POLR2B UBR4 NUCB2 NSUN2 IQGAP1 EIF3CL TRIM16 CTR9 ARHGEF1 CSNK2A2 RTRAF EIF5 EIF3A EIF3C

7.47e-0614551291822863883
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

MRE11 SPAG1 EVPL CC2D1A IQGAP1 ARHGAP5 TJP1 EIF5 STEAP3 UTRN USP6NL

8.93e-065651291125468996
Pubmed

Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.

EIF3CL EIF3A EIF3C

1.07e-0512129314519125
Pubmed

Reconstitution reveals the functional core of mammalian eIF3.

EIF3CL EIF3A EIF3C

1.07e-0512129317581632
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MRE11 POLR2B INO80D NDUFB9 IQGAP1 CCDC59 CTR9 CSNK2A2 RTRAF EIF5 SMARCA2 WDR89 EIF3A EIF3C TAF5 ITM2B UTRN USP6NL

1.10e-0514971291831527615
Pubmed

Obscurin regulates the organization of myosin into A bands.

MYH2 OBSCN

1.37e-052129215013951
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

1.37e-05212928670841
Pubmed

Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis.

ARHGAP35 EIF3A

1.37e-052129228007963
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

1.37e-052129223163725
Pubmed

Glomerular-specific imprinting of the mouse gsalpha gene: how does this relate to hormone resistance in albright hereditary osteodystrophy?

GNAS UTRN

1.37e-05212928812454
Pubmed

Loss of MLL5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation.

KMT2E STEAP3

1.37e-052129218854576
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

1.37e-052129223076393
Pubmed

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

SMARCA2 SMARCA4

1.37e-05212929603422
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

1.37e-052129215576411
Pubmed

RhoA is down-regulated at cell-cell contacts via p190RhoGAP-B in response to tensional homeostasis.

ARHGAP35 ARHGAP5

1.37e-052129223552690
Pubmed

SWI/SNF gene variants and glioma risk and outcome.

SMARCA2 SMARCA4

1.37e-052129223276717
Pubmed

Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.

SMARCA2 SMARCA4

1.37e-052129227097303
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

1.37e-052129215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

1.37e-052129226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

1.37e-052129233027072
Pubmed

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

SMARCA2 SMARCA4

1.37e-052129228038711
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

1.37e-052129223872584
Pubmed

Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.

SMARCA2 SMARCA4

1.37e-052129223963727
Pubmed

SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.

SMARCA2 SMARCA4

1.37e-052129212493776
Pubmed

Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.

SMARCA2 SMARCA4

1.37e-052129231375262
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

1.37e-052129223088494
Pubmed

A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II.

GRIN2B SYNGAP1

1.37e-05212929620694
Pubmed

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.

SMARCA2 SMARCA4

1.37e-052129217075831
Pubmed

Functional and biochemical characterization of human eukaryotic translation initiation factor 3 in living cells.

EIF3A EIF3C

1.37e-052129224912683
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

1.37e-052129220333683
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

1.37e-052129234812766
Pubmed

Positional cloning reveals strain-dependent expression of Trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice.

TRIM16 TRIM16L

1.37e-052129223341783
Pubmed

EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.

EIF3CL EIF3C

1.37e-052129236157221
Pubmed

The estrogen-responsive B box protein: a novel regulator of keratinocyte differentiation.

TRIM16 TRIM16L

1.37e-052129211919186
Pubmed

Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.

SMARCA2 SMARCA4

1.37e-052129232855269
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

1.37e-052129230478150
Pubmed

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.

SMARCA2 SMARCA4

1.37e-052129222721696
Pubmed

Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.

SMARCA2 SMARCA4

1.37e-052129218508913
Pubmed

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.

SMARCA2 SMARCA4

1.37e-052129211719516
Pubmed

Proliferation-associated SNF2-like gene (PASG): a SNF2 family member altered in leukemia.

SMARCA2 HELLS

1.37e-052129210910076
Pubmed

Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1.

TRIM16 TRIM16L

1.37e-052129234146477
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

1.37e-052129225808524
Pubmed

A novel putative helicase produced in early murine lymphocytes.

SMARCA4 HELLS

1.37e-05212928647447
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

1.37e-052129219144648
Pubmed

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.

SMARCA2 SMARCA4

1.37e-052129228706277
Pubmed

Heterozygous loss of keratinocyte TRIM16 expression increases melanocytic cell lesions and lymph node metastasis.

TRIM16 TRIM16L

1.37e-052129231342168
Pubmed

[Expression of BRG1 and BRM proteins in prostatic cancer].

SMARCA2 SMARCA4

1.37e-052129221092585
Pubmed

The p190 RhoGAPs, ARHGAP35, and ARHGAP5 are implicated in GnRH neuronal development: Evidence from patients with idiopathic hypogonadotropic hypogonadism, zebrafish, and in vitro GAP activity assay.

ARHGAP35 ARHGAP5

1.37e-052129236178483
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

1.37e-052129229391527
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

1.37e-052129237634210
Pubmed

SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.

SMARCA2 SMARCA4

1.37e-052129226551623
Pubmed

Expression and distribution of ZO-3, a tight junction MAGUK protein, in mouse tissues.

TJP1 TJP3

1.37e-052129214622136
Pubmed

The E3 Ligase TRIM16 Is a Key Suppressor of Pathological Cardiac Hypertrophy.

TRIM16 TRIM16L

1.37e-052129235437018
Pubmed

SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.

SMARCA2 SMARCA4

1.37e-052129219458193
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

1.37e-05212928208605
Pubmed

TRIM16 protects from OGD/R-induced oxidative stress in cultured hippocampal neurons by enhancing Nrf2/ARE antioxidant signaling via downregulation of Keap1.

TRIM16 TRIM16L

1.37e-052129232251645
Pubmed

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.

SMARCA2 SMARCA4

1.37e-052129234289068
Pubmed

SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.

SMARCA2 SMARCA4

1.37e-052129234518526
Pubmed

SMARCA family of genes.

SMARCA2 SMARCA4

1.37e-052129232312722
Pubmed

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

SMARCA2 SMARCA4

1.37e-052129226356327
Pubmed

Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.

SMARCA2 SMARCA4

1.37e-052129212566296
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

1.37e-052129211163203
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

1.37e-052129212620226
Pubmed

SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.

SMARCA2 SMARCA4

1.37e-052129231406271
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

1.37e-052129227039070
Pubmed

Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.

SMARCA2 SMARCA4

1.37e-052129229848589
Pubmed

Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.

SMARCA2 SMARCA4

1.37e-052129229273066
Pubmed

Therapeutic significance of NR2B-containing NMDA receptors and mGluR5 metabotropic glutamate receptors in mediating the synaptotoxic effects of β-amyloid oligomers on long-term potentiation (LTP) in murine hippocampal slices.

GRIN2B GRM5

1.37e-052129221310164
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

MRE11 BEND3 IQGAP1 ATAD3B CTR9 RTRAF SMARCA2 SMARCA4 EIF3A EIF3C HELLS

1.68e-056051291128977666
Pubmed

Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3.

EIF3CL EIF3A EIF3C

1.76e-0514129318599441
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

TRPM6 ADAM19 POLR2B KMT2E EIF3CL KCNA4 CSNK2A2 SMARCA2 SMARCA4 EIF3C TAF5 DNAH5

1.87e-057301291234857952
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

MRE11 POLR2B UBR4 CC2D1A ARHGAP35 NSUN2 IQGAP1 TJP1 CTR9 ARHGEF1 CSNK2A2 RTRAF SMARCA4 EIF3A EIF3C NBR1 HELLS

1.99e-0514151291728515276
Pubmed

Identification of Novel Proteins Co-Purifying with Cockayne Syndrome Group B (CSB) Reveals Potential Roles for CSB in RNA Metabolism and Chromatin Dynamics.

POLR2B CTR9 SMARCA2 SMARCA4

1.99e-0543129426030138
Pubmed

Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.

EIF3CL EIF3A EIF3C

2.20e-0515129317322308
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

ADAM19 UBR4 GRIN2B NSUN2 IQGAP1 SYNGAP1 ARHGAP5 ODF2L TJP1 CTR9 RTRAF SMARCA4 CCDC15 ANKRD36 EIF3C UTRN

2.32e-0512851291635914814
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MRE11 MYH2 BEND3 IQGAP1 ATAD3B USP38 TJP1 CSNK2A2 SMARCA2 EIF3A GNAL EIF3C UTRN ELL

2.32e-0510051291419615732
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

MRE11 UBR4 EIF3CL SMARCA4 EIF3A EIF3C

2.39e-05153129626365490
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

DHX16 MRE11 ANXA6 POLR2B NSUN2 IQGAP1 TJP1 RTRAF SMARCA4 EIF3A EIF3C GNAS UTRN HELLS

2.85e-0510241291424711643
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

DHX16 MRE11 POLR2B UBR4 IDH2 NSUN2 EIF3CL TAOK3 CTR9 ARHGEF1 CSNK2A2 RTRAF SMARCA2 SMARCA4 EIF3A TAF5

3.15e-0513181291630463901
Pubmed

Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors.

MRE11 SLC12A9 TJP1

3.26e-0517129311060040
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

DHX16 POLR2B CC2D1A SNUPN WWC2 TJP1 CTR9 ARHGEF1 CSNK2A2 EIF5 WDR89 EIF3C GNAS TJP3

3.30e-0510381291426673895
Pubmed

DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.

POLR2B SMARCA2 SMARCA4 EIF3A ELL

3.51e-0599129534161765
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

KIF21B MRE11 NSUN2 IQGAP1 TJP1 CTR9 CSNK2A2 EIF3A EIF3C GNAS USP6NL

3.72e-056601291132780723
Pubmed

Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.

SMARCA2 SMARCA4

4.09e-053129228292935
Pubmed

Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.

SMARCA2 SMARCA4

4.09e-053129236464671
Pubmed

DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.

SMARCA2 SMARCA4

4.09e-053129230287812
GeneFamilyBasic helix-loop-helix proteins|MAX dimerization proteins

MLX MXD4

3.90e-047792637
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

KIF21B ADAM19 SLF1 ANXA6 POLR2B UBR4 TMC6 ARHGAP35 KMT2E LYST INO80D MXD4 IQGAP1 CCDC88C TAOK3 ARHGEF1 EIF5 SMARCA2 LPGAT1 GNAS ITM2B UTRN ELL

9.86e-07149212923M40023
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 IDH2 ANKRD36C KIF24 ODF2L FAM161A CCDC15 SYT5 ANKRD36 CCDC181 CCDC171 PLCE1 HELLS

4.51e-16190129140adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 IDH2 ANKRD36C KIF24 ODF2L FAM161A CCDC15 SYT5 ANKRD36 CCDC181 CCDC171 PLCE1 HELLS

4.51e-161901291405455775845f4ded5c27e7b83242078d23162aaf
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 IDH2 KIF24 ASAP2 FAM161A BUB1 SYT5 CCDC181 CCDC171 PLCE1 HELLS

1.89e-1317912912d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 IDH2 KIF24 ASAP2 FAM161A BUB1 SYT5 CCDC181 CCDC171 PLCE1 HELLS

1.89e-1317912912e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 IDH2 KIF24 BUB1 SYT5 CCDC181 CCDC171 PLCE1 HELLS

2.26e-1019012910da60bcc4b59d8e3719d8201387d567594059b1a4
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 IDH2 KIF24 BUB1 SYT5 CCDC181 CCDC171 PLCE1 HELLS

2.26e-1019012910827a1f4e4ac4beada262f4fb965dd74a447a8f4f
ToppCellmoderate-Epithelial-FOXN4+|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPAG1 ANKRD36C KIF24 ASAP2 FAM161A SYT5 ANKRD36 CCDC171 PLCE1 HELLS

2.77e-10194129105dffa578149104dda33774361e9e77b227b5f1ce
ToppCell(11)_FOXN4+|World / shred by cell type by condition

SPAG1 CFAP36 NUCB2 IDH2 KIF24 BUB1 SYT5 CCDC181 CCDC171 HELLS

3.39e-1019812910516b1acdf997dd8debc3dca066519366e507b414
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC146 NUCB2 KIF24 BUB1 SYT5 CCDC181 CCDC171 HELLS

4.90e-091911299a6c9df4cb4d09e0a91b3c8d7f3e091a7e95e6471
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KIF24 FAM161A BUB1 SYT5 ANKRD36 CCDC171 UTRN PLCE1 HELLS

5.61e-091941299dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG1 EFCAB11 CCDC30 CCDC146 CFAP36 KIF24 ODF2L FAM161A

4.36e-081741298179a52d77899a929396b98d4ab2c270dd2ec708e
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPAG1 EFCAB11 CCDC30 CCDC146 CFAP36 KIF24 ODF2L FAM161A

4.36e-0817412989165a1094d345328e58962f4b2a20334c3e93ead
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 BUB1 CCDC15 CCDC181 CCDC171 SMC1B PLCE1 HELLS

5.67e-0818012980c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 BUB1 CCDC15 CCDC181 CCDC171 SMC1B PLCE1 HELLS

5.67e-081801298e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 BUB1 CCDC15 CCDC181 CCDC171 SMC1B PLCE1 HELLS

5.67e-08180129811455ba704ac73f69b474845136cfecec6a88349
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF24 ASAP2 FAM161A BUB1 SYT5 CCDC171 PLCE1 HELLS

8.60e-081901298250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 NUCB2 ATP10B SYT5 CCDC181 DNAH5

1.05e-071951298d211a836cf711fdb91b10d512f09d462be937cc5
ToppCellNS-critical-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF24 ASAP2 BUB1 SYT5 CCDC171 PLCE1 HELLS

8.32e-0717612977cf1a06ceee1ec06532f44c729c31b4d58e5ea49
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPAG1 CCDC146 KIF24 BUB1 SYT5 CCDC171 HELLS

1.04e-061821297deb53a4f84e4cd5c3b4180a4ac43249da9d738f7
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN SFI1 GRIN2B KCNA4 NRK DNAH5 PLCE1

1.12e-0618412972cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN SFI1 GRIN2B KCNA4 NRK DNAH5 PLCE1

1.12e-061841297ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN SFI1 GRIN2B KCNA4 NRK DNAH5 PLCE1

1.12e-0618412972b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell15-Trachea-Epithelial-Multiciliated_precursor|Trachea / Age, Tissue, Lineage and Cell class

SPAG1 KIF24 FAM161A CCDC15 SYT5 CCDC181 CCDC171

1.16e-0618512979a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

SLF1 CCDC30 CCDC146 CFAP36 FAM161A CCDC181 DNAH5

1.29e-0618812978f30535a32968a81a304315a49c0d90a77d36948
ToppCellEpithelial-D_(Ciliated)|World / shred on cell class and cell subclass (v4)

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5 TJP3

1.34e-0618912970bf560b595c7a8450a46bc821b742b67965bd9f9
ToppCellNS-critical-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF24 ASAP2 BUB1 GNAL CCDC171 PLCE1 HELLS

1.39e-0619012977be0f2ff86ca8500a43e0d44e5e292530f9ba0bb
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC146 NUCB2 KIF24 SYT5 PLCE1 HELLS

1.44e-061911297683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

KNTC1 ADAM19 SFI1 ANKRD36C LYST IQGAP1 HELLS

1.44e-0619112979454f642c3621370fa23640b631301346b300950
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC30 CCDC146 C1orf87 NUCB2 ODF2L CCDC181 DNAH5

1.54e-061931297c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCellPSB-critical-LOC-Epithelial-FOXN4+|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ASAP2 BUB1 CCDC15 SYT5 CCDC171 PLCE1 HELLS

1.54e-061931297b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KNTC1 MRE11 SLF1 KIF24 CCDC15 ZNF730 HELLS

1.71e-061961297df366d76ea55f49e349d622effa57c1535df8400
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 CFAP36 NUCB2 CCDC181 DNAH5

1.71e-0619612971386003f5d885f0ea080934f7e05fe05f142a3d5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM19 SLF1 ANXA6 IDH2 LYST MXD4 ARHGEF1

1.77e-0619712971ca06d6d288cb58a6e8062ebc01831e58ee5be4b
ToppCellcritical-Epithelial-FOXN4+|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KIF24 ASAP2 ANKRD36 GNAL CCDC171 PLCE1 HELLS

1.83e-0619812976b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CCDC146 C1orf87 KIF24 SYT5 XRRA1 CCDC181 DNAH5

1.89e-06199129715f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF24 FAM161A SYT5 CCDC171 PLCE1 HELLS

6.55e-061571296410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR26 GRIN2B GRM5 KCNA4 SYT5 GNAL

9.65e-061681296b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR26 GRIN2B GRM5 KCNA4 SYT5 GNAL

9.65e-061681296b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 BRME1 KIF24 BUB1 ZNF730 HELLS

9.98e-061691296121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC30 CCDC146 GRM5 CCDC88C ODF2L DNAH5

9.98e-06169129614aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellfacs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.14e-05173129627ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC30 CCDC146 C1orf87 FAM161A CCDC181 DNAH5

1.38e-051791296d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CCDC30 CCDC146 C1orf87 FAM161A CCDC181 DNAH5

1.38e-0517912968a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 C1orf87 FAM161A CCDC181 DNAH5

1.62e-051841296797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 C1orf87 FAM161A CCDC181 DNAH5

1.62e-05184129677d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellPND28-Epithelial-Epithelial_Airway|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.77e-051871296f777dd5eb5ccd554ebe1ed60a738b5dd45e18bb9
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

EFCAB11 CCDC30 CCDC146 SFI1 FAM161A DNAH5

1.83e-051881296f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

ANKRD36C INO80D RLF ANKRD36 CENATAC UTRN

1.83e-051881296ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.88e-051891296057d7a03fdbe779122b203619a6f947f49b84d28
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A CCDC181 DNAH5 TJP3

1.88e-051891296b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.88e-051891296fa1ff8b7fa53f3148d9117d6e598097f03af5eb2
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A CCDC181 DNAH5 TJP3

1.88e-05189129638cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.88e-0518912969f57a131902d23494bf389baf6e6e2d99f88b2c8
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.88e-051891296565063f9e3dd79164321f8a394bd12c176baf202
ToppCellPND28-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.88e-051891296497be236848ebf5ad75d1f0c71e6261f5d3521da
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A CCDC181 DNAH5 TJP3

1.88e-0518912964e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellPND07-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.88e-051891296e443b02502edaefa94567a9e8af5756e8e11ff30
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.94e-051901296088e3f39a1e5e11354d6e7458e8e6a39f14936b3
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.94e-05190129635248a8be476ea8d06d67c3d98a25be1f7c150b7
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAM19 KMT2E SMARCA2 SMARCA4 EIF3A UTRN

1.94e-051901296d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellPND14-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

1.94e-0519012965f5206f9e725070d865f4c891ff08bb750e58582
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 NUCB2 ATP10B ANKRD36C SYT5 TJP3

1.94e-0519012962fdc024d3d673a0134b74b4c5a63afe924995730
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

2.00e-051911296bda8faf92495c8b362850c0aff4fc6fbdd9c563b
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

2.00e-0519112966880fb348bb0915db9a5da4f3566ca9ff93ed258
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC30 CCDC146 C1orf87 NUCB2 ODF2L DNAH5

2.00e-0519112960c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCellPND07-Epithelial-Epithelial_Airway|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

2.00e-051911296b55500eb416f4f339031acad16b2737e5b891d8e
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A CCDC181 DNAH5 TJP3

2.00e-05191129696483adb97c81208aa513782550acd8a08b63866
ToppCellPND03-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

2.06e-051921296b5cdc2dae3154b1e4ade88f841f38584402ffe33
ToppCellASK428-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CCDC30 CCDC146 C1orf87 NUCB2 ODF2L DNAH5

2.06e-051921296356ebddd03aec341b79890977edb8ff0804999a1
ToppCellPND03-Epithelial-Epithelial_Airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC30 CCDC146 FAM161A SYT5 CCDC181 DNAH5

2.06e-0519212962d8d5a38e205339eda9c8aca1ca9ba3dcbe5ae56
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 SYT5 CCDC181 DNAH5

2.18e-0519412963cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 NUCB2 CCDC181 DNAH5

2.24e-051951296649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KNTC1 SLF1 KIF24 CCDC15 ZNF730 HELLS

2.24e-051951296cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 C1orf87 CCDC181 DNAH5

2.24e-0519512960e763f36786515698b593e5c93f6a56619c1242d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 SYT5 CCDC181 DNAH5

2.24e-051951296db4270c135c392ed443670981656e3cd5b95939d
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 NUCB2 CCDC181 DNAH5

2.24e-051951296129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 NUCB2 CCDC181 DNAH5

2.24e-0519512963e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 SYT5 CCDC181 DNAH5

2.24e-0519512966365e3893e38231090ec2dbef010dec71dea3d07
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPAG1 CCDC30 CCDC146 NUCB2 CCDC181 DNAH5

2.24e-0519512969651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KNTC1 MRE11 SLF1 CCDC15 ZNF730 HELLS

2.24e-05195129656d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF24 BUB1 CCDC15 ZNF730 HELLS

2.31e-0519612961d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADAM19 ANXA6 MXD4 CCDC88C WDR89 UTRN

2.31e-051961296c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCellControl-Classical_Monocyte-cMono_2|Classical_Monocyte / Disease condition and Cell class

LYST IQGAP1 RTRAF EIF5 EIF3A GNAS

2.38e-051971296eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KNTC1 KIF24 BUB1 CCDC15 ZNF730 HELLS

2.38e-0519712968b616cde333bdbc0c591035ad9e4949155866245
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM19 ANXA6 IDH2 CCDC88C ODF2L ARHGEF1

2.38e-051971296927bf36bad3bcb7346c13b660777c1c0de7dc322
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAM19 ANXA6 IDH2 CCDC88C ODF2L ARHGEF1

2.38e-0519712963e09158507df08c08e08613ce23617206280c911
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-CD8+_T_naive|Int-URO / Disease, condition lineage and cell class

DCPS NUCB2 OBSCN ZNF257 EIF3C DSEL

2.44e-0519812968c7d00d8c27fb47954d8ac53eebc4582e92b970c
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Ciliated|LPS_only / Treatment groups by lineage, cell group, cell type

CCDC30 CCDC146 C1orf87 SLC12A9 CCDC181 DNAH5

2.44e-0519812966d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SPAG1 CCDC146 ODF2L SMARCA2 ANKRD36 GNAS

2.51e-05199129661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPAG1 EVPL ANKRD36C ARHGAP5 TJP1 TJP3

2.51e-0519912965a1557fe35aa48080d4967e8724bf27f9585a5fb
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPAG1 EVPL ANKRD36C ARHGAP5 TJP1 TJP3

2.51e-0519912960a657475b92aa3a713da62da364525249fdc3886
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPAG1 EVPL ANKRD36C ARHGAP5 TJP1 TJP3

2.51e-051991296a8f4bd0e65f36b29535864fae4347369d5c864d2
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KNTC1 KIF24 FAM161A BUB1 CCDC15 HELLS

2.51e-0519912961d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellNS-critical-d_16-33-Epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPAG1 CCDC146 NUCB2 TJP1 DNAH5 TJP3

2.51e-0519912963b68197ec01c5f2b315d9e9b6eb02d5f6b5b77a3
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SPAG1 EVPL ANKRD36C ARHGAP5 TJP1 TJP3

2.51e-051991296eacea42e973f073b410f54c0a1b3a7f2dc2b5a29
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

WWC2 ARHGEF1 SMARCA4 DSEL UTRN TJP3

2.59e-052001296ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SPAG1 CCDC30 CCDC146 C1orf87 CCDC181 DNAH5

2.59e-0520012967cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

WWC2 SLC12A9 ARHGEF1 SMARCA4 UTRN TJP3

2.59e-0520012968683445ad5b70748c4a1f12eb77d47623085147e
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPAG1 CCDC30 CCDC146 C1orf87 CCDC181 DNAH5

2.59e-052001296f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

SPAG1 CCDC30 CCDC146 C1orf87 CCDC181 DNAH5

2.59e-052001296d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

1.79e-0451262C3281201
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

6.39e-0491262DOID:0050340 (implicated_via_orthology)
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

1.37e-03131262C0265338
Diseasethyroid volume

SMARCA2 DNAH5

2.09e-03161262EFO_0004865
Diseaselevel of Sphingomyelin (d32:1) in blood serum

SMARCA4 WDR89

2.36e-03171262OBA_2045173

Protein segments in the cluster

PeptideGeneStartEntry
KDYQRRLDLSHLRQS

ARHGEF1

616

Q92888
KLAHIKRLIAEYDQR

ELL

601

P55199
FEELRAQKYNQRRKH

BUB1

251

O43683
RAAKTLYHKRQASRI

HTR1F

206

P30939
RRKLLAQKYHDNAQL

ADAM19

286

Q9H013
TEELRQREHYLKQKR

CFAP36

266

Q96G28
RANEKIRHLEYICKN

CCDC171

616

Q6TFL3
NLYLQHKIFEALRRK

CCDC96

246

Q2M329
YDANKRDRKERTALH

ANKRD36

56

A6QL64
ELSRHERQELKYKRR

DHX16

261

O60231
TEKHLQKYLRQDLRL

DCPS

136

Q96C86
RKIRARTQKHLDLYA

ATP10B

816

O94823
LEKERARRLIHNYNL

C1orf87

496

Q8N0U7
RSKQHLRLVFDEYLK

ANXA6

206

P08133
AQHYQDTLIRAKREK

IQGAP1

576

P46940
EQRKLREERHQEYLK

NOL12

56

Q9UGY1
LALEHLLRKRDYKQT

ODF2L

111

Q9ULJ1
YKDRRRRAHTQAEQK

MLX

126

Q9UH92
VDNKRCYLLVHQAKR

NSUN2

216

Q08J23
KRKLESLHLQLIRNY

BEND3

296

Q5T5X7
YDINKRDRKERTALH

ANKRD36C

56

Q5JPF3
AKQRLKRLRNIHYLF

FAR2

456

Q96K12
QLYRRKKDNHALVRE

ELOA2

566

Q8IYF1
IYTLRNKEVKHALQR

OR10S1

301

Q8NGN2
RRLQHLLEKSNIYSK

HELLS

66

Q9NRZ9
LRYKDRRLAQHKSEI

GRM5

876

P41594
LLLKKHLENNYRSRD

LPGAT1

161

Q92604
VVHEKRELYRKRQSQ

MAP10

516

Q9P2G4
LEKHRRAKLRLYLEQ

MXD4

61

Q14582
RLCHDKETYKLQRRE

ITM2B

221

Q9Y287
IERRYARKKHADNAA

ASAP2

531

O43150
RRLHYNEELNIKLAR

PPP1R2C

141

O14990
EQKQYIDKLNALRRH

CCDC88C

1366

Q9P219
LLRHQYRKSCKEILN

GPR26

296

Q8NDV2
YRKSCKEILNRLLHR

GPR26

301

Q8NDV2
LRKHERRVKELTYQT

MYH2

1846

Q9UKX2
QIYEKERTLRDLHAK

EVPL

1651

Q92817
SQRRLQTLKHQYEEK

KIF21B

656

O75037
HARLLKNQSRYEREL

KIF21B

731

O75037
AQELRRRAEDYHKCK

NPIPB8

206

E9PQR5
LNRRKRLFAREDSKH

KIF24

371

Q5T7B8
YQRALLLSDHRKDKD

KMT2E

1266

Q8IZD2
NLRELITLHRKYNCK

KNTC1

691

P50748
ALAYLDQRAERILHK

MFSD1

231

Q9H3U5
HERREYLKTLNEEKR

NUCB2

186

P80303
QLQKERLAYKATHRL

GNAL

31

P38405
REKRRALLYKRHNLA

OBSCN

7951

Q5VST9
RDYRHTRKLLNVLKE

FAM9A

166

Q8IZU1
RLEAKRSKQLQHHLY

CCDC181

481

Q5TID7
LRQKIRKYNRDFESH

EIF3C

141

Q99613
LRQKIRKYNRDFESH

EIF3CL

141

B5ME19
EKYRHRLKCQRLSSE

C5orf47

156

Q569G3
NEKIREQIKKYRRHF

EIF5

286

P55010
SQEQPRRHYADKRIK

IDH2

31

P48735
HRDLEAFKRLNYRKT

BRME1

626

Q0VDD7
AYLKNSRKEHQRILA

EIF3A

556

Q14152
LKINSADREKYRRLN

DENND11

351

A4D1U4
KRHQDRALAIYKQVL

CTR9

626

Q6PD62
QSRQRDYKLAALHAK

CC2D1A

261

Q6P1N0
KRKLLYQNVDELHRQ

CCDC30

406

Q5VVM6
LQHRVQLKYAAKRLR

DDX12P

166

Q92771
QKDKQVYRATHRLLL

GNAS

31

P63092
LLDKLLRYDHQQRLT

CSNK2A2

301

P19784
QRKITHRYSVRDARK

LYST

146

Q99698
KYKHLCRLERAESRQ

INO80D

381

Q53TQ3
VYSRKHQRQLKEALE

CENATAC

21

Q86UT8
YHDLVKQKEERRRSL

FAM161A

296

Q3B820
KKEAQRYRNEVRHIF

EFCAB11

86

Q9BUY7
NLLDNHRRQKYLEKI

DSEL

186

Q8IZU8
AQELRRRAEDYHKCK

NPIPB6

206

E9PJ23
KEAKRALLDARHNYL

DNAH5

26

Q8TE73
LKNNREISRIFHYIK

FAM120B

106

Q96EK7
QYHRILKRRQARAKL

NFYA

271

P23511
RTELNLLRKYSFHKN

NRK

91

Q7Z2Y5
RRAQEYRHQLLKKEQ

GABPB2

366

Q8TAK5
KELSKRLNHRNYLLE

PLEKHM1

941

Q9Y4G2
KIRHYKIEDRGNLRN

RTRAF

36

Q9Y224
KRRRYETKVHRQTLN

SYT5

156

O00445
RDSYQLLKRHLQEKQ

TAF5

311

Q15542
KRRYKQLLQARADGH

SFI1

466

A8K8P3
QLQYDHCKALRRELK

UTRN

2596

P46939
LSHYKERLNRRSRKL

TRIM40

111

Q6P9F5
ERKRRQKHQEYLNSI

SMARCA2

441

P51531
VARLEKHKNLFLNYR

LRRC28

11

Q86X40
LEKRHSLEYSLRIQK

LSAMP

86

Q13449
DRQLNLRLLKKHNYN

NBR1

931

Q14596
LKALKRGYRHLQLRN

PLCE1

1956

Q9P212
THQQKVLRLYKRALR

NDUFB9

11

Q9Y6M9
RKRRQKHQEYLNSIL

SMARCA4

466

P51532
KERIRNHKYRSLNDL

SMARCA4

1511

P51532
KKRHIDQLKEREYNN

POLR2B

636

P30876
QLEYNKRRERELHRK

TAOK3

686

Q9H2K8
LYLAEEERHRKQARK

CCDC59

96

Q9P031
LKQEHIRKRREEYIN

ARHGAP5

326

Q13017
QKSKRLDYVNHARRL

SNUPN

51

O95149
YQLEKTQRFLKERHI

MRE11

476

P49959
SNKDKLHLYERTRDL

RGMA

406

Q96B86
YEAHLEKLRNERKRV

ARHGAP35

416

Q9NRY4
LRKRYEKAVQHRNES

CCDC146

626

Q8IYE0
DKKERQKQYLRHRRL

CCDC15

766

Q0P6D6
RNTKKNRGLYRHILL

ATAD3B

336

Q5T9A4
KLAQKYDHQREQELR

CNN1

21

P51911
TIEYLKRHNALLSKR

TMEM192

241

Q8IY95
EETRDLYSKLKHRAR

USP6NL

121

Q92738
LRTQKELYHVKEQRL

WWC2

111

Q6AWC2
RRNLEKYLSLQKIHC

TRPM6

266

Q9BX84
KQYRRRDLTDQHKEK

RLF

521

Q13129
RRAHRYDLVNLAVKQ

STEAP3

326

Q658P3
RALRLHLYRDSDKKR

SYNGAP1

321

Q96PV0
RLNVQLEYSRSHLKK

SMC1B

816

Q8NDV3
TRLKYLHEKNQRQRQ

TMEM247

116

A6NEH6
HQVRKYLLRLDVRKD

SLC12A9

511

Q9BXP2
RRATTYKHQNKLREA

SPAG1

281

Q07617
DQKYHVRRKILDNVS

USP38

771

Q8NB14
IKSTLRRHIYNRDQK

SLF1

331

Q9BQI6
RQYKKCRHENLLLRK

ZNF730

101

Q6ZMV8
RRYEKCGHDNLQLRK

ZNF141

101

Q15928
ARKLYERSHKLRKNN

TJP1

751

Q07157
TRRLYAQAQKLRKHS

TJP3

721

O95049
RRYDKRGHENLQLRK

ZNF429

101

Q86V71
TAHKYLRLQEENRKV

TRIM16

381

O95361
FLINKLHSIYERKER

TMC6

766

Q7Z403
ERHKREKEYLLNQAA

TXLNB

326

Q8N3L3
QRVRVHSNDSYKRRK

WDR89

371

Q96FK6
KEKYRQLRDLHTLDS

UBR4

3221

Q5T4S7
RKENLLYNKERLTHS

WDR87

1856

Q6ZQQ6
LRNYRKDLAKLHREV

VTI1B

81

Q9UEU0
TERRLVNHKQYLEAK

XRRA1

716

Q6P2D8
QKVILRRYEKCRHDN

ZNF506

96

Q5JVG8
RRYEKCRHDNLQLKK

ZNF506

101

Q5JVG8
AHKYLRLQEENRKVT

TRIM16L

166

Q309B1
RRYDKCEHENLQLRK

ZNF257

101

Q9Y2Q1
RRQRSEKKKAHYRQS

KCNA4

86

P22459
QKKNRNKLRRQHSYD

GRIN2B

1291

Q13224