Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	-	MICAL2 CEP95	5.05e-03	71	28	2	1.10.418.10
Domain	CH-domain	MICAL2 CEP95	5.62e-03	75	28	2	IPR001715
Domain	-	NEUROG2 HES7	1.16e-02	109	28	2	4.10.280.10
Domain	HLH	NEUROG2 HES7	1.20e-02	111	28	2	PF00010
Domain	HLH	NEUROG2 HES7	1.30e-02	116	28	2	SM00353
Domain	BHLH	NEUROG2 HES7	1.32e-02	117	28	2	PS50888
Domain	bHLH_dom	NEUROG2 HES7	1.34e-02	118	28	2	IPR011598
Pubmed	Drosha regulates neurogenesis by controlling neurogenin 2 expression independent of microRNAs.	NEUROG2 DROSHA	1.87e-06	3	28	2	22706270
Pubmed	Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition.	FUT8 DROSHA	1.31e-05	7	28	2	18381897
Pubmed	Shifts in the vascular endothelial growth factor isoforms result in transcriptome changes correlated with early neural stem cell proliferation and differentiation in mouse forebrain.	NEUROG2 FEZF2	2.80e-05	10	28	2	24124161
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DOCK3 MRPL38 SNRNP70 FUT8 FEZF2 MICAL2 DROSHA	5.53e-05	1285	28	7	35914814
Pubmed	Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development.	NEUROG2 FEZF2	5.65e-05	14	28	2	26138486
Pubmed	Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.	NEUROG2 FEZF2	5.65e-05	14	28	2	18160702
Pubmed	Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis.	NEUROG2 HES7	5.65e-05	14	28	2	26728556
Pubmed	Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrain.	NEUROG2 FEZF2	7.45e-05	16	28	2	20431123
Pubmed	A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis.	NEUROG2 FEZF2	8.44e-05	17	28	2	30201687
Pubmed	Mouse Nkd1, a Wnt antagonist, exhibits oscillatory gene expression in the PSM under the control of Notch signaling.	NKD2 HES7	8.44e-05	17	28	2	15511637
Pubmed	Neurog2 and Ascl1 together regulate a postmitotic derepression circuit to govern laminar fate specification in the murine neocortex.	NEUROG2 FEZF2	1.30e-04	21	28	2	28584103
Pubmed	Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway.	CCAR2 CPSF7	1.43e-04	22	28	2	32241891
Pubmed	FGF11 induced by hypoxia interacts with HIF-1α and enhances its stability.	CCAR2 LZTS3 MRPL49	1.49e-04	128	28	3	28027390
Pubmed	Cortical Development Requires Mesodermal Expression of Tbx1, a Gene Haploinsufficient in 22q11.2 Deletion Syndrome.	NEUROG2 FEZF2	1.56e-04	23	28	2	27005988
Pubmed	Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.	LATS1 SNRNP70 CPSF7	1.67e-04	133	28	3	15144186
Pubmed	Conserved transcriptional regulation by BRN1 and BRN2 in neocortical progenitors drives mammalian neural specification and neocortical expansion.	NEUROG2 FEZF2	1.85e-04	25	28	2	39271675
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	DOCK3 SNRNP70 CEP95 CPSF7	1.92e-04	361	28	4	26167880
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	MRPL38 GAPVD1 NKD2 LZTS3 TPRN	2.03e-04	689	28	5	36543142
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	CCAR2 MRPL38 SNRNP70 MRPL49 CPSF7	2.37e-04	713	28	5	29802200
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	CCAR2 GAPVD1 SNRNP70 CPSF7	2.81e-04	399	28	4	35987950
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	MRPL38 SNRNP70 CPSF7	3.04e-04	163	28	3	22113938
Pubmed	Six3 inactivation causes progressive caudalization and aberrant patterning of the mammalian diencephalon.	NEUROG2 FEZF2	3.87e-04	36	28	2	18094027
Pubmed	Tissue-Specific Actions of Pax6 on Proliferation and Differentiation Balance in Developing Forebrain Are Foxg1 Dependent.	NEUROG2 FEZF2	4.55e-04	39	28	2	30529950
Pubmed	Olig3 regulates early cerebellar development.	NEUROG2 HES7	4.78e-04	40	28	2	33591268
Pubmed	Dynamic spatiotemporal gene expression in embryonic mouse thalamus.	NEUROG2 EPHA8	5.03e-04	41	28	2	21192082
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	GAPVD1 LATS1 NKD2 CEP95 STARD9	5.63e-04	861	28	5	36931259
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	LZTS3 DROSHA CPSF7	7.28e-04	220	28	3	24550385
GeneFamily	Mitochondrial ribosomal proteins	MRPL38 MRPL49	2.76e-03	79	18	2	646
GeneFamily	Basic helix-loop-helix proteins	NEUROG2 HES7	5.27e-03	110	18	2	420
GeneFamily	RNA binding motif containing	SNRNP70 CPSF7	1.87e-02	213	18	2	725
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP	OCEL1 FUT8 FEZF2 CPSF7	5.83e-05	200	28	4	M9655
Coexpression	GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN	OCEL1 SNRNP70 FEZF2 CPSF7	5.83e-05	200	28	4	M7904
Disease	N-acetylmethionine measurement	DOCK3 MICAL2	9.05e-05	15	28	2	EFO_0021427
Disease	macrophage inflammatory protein 1b measurement	ZNF438 DOCK3	7.37e-03	136	28	2	EFO_0008219

Protein segments in the cluster

Peptide	Gene	Start	Entry
KPRHDLPPYRVHLTP	CCAR2	216	Q8N163
IHYQHLMPPPPRLPP	CPSF7	261	Q8N684
PKGHKPRPHPVPDYE	OCEL1	136	Q9H607
APPQYREPSHPPKLL	LZTS3	131	O60299
WQPPPPDKHRYAPHL	NEUROG2	251	Q9H2A3
PPPYPKHLLHQNPSV	LATS1	556	O95835
PLAVPYLDKPPTPLH	JMJD7	26	P0C870
VRPKVHYARPSHPPP	GAPVD1	841	Q14C86
HYARPSHPPPDPPIL	GAPVD1	846	Q14C86
HLPQPPPPPYGHKRY	NKD2	371	Q969F2
HKPVPYPIPPCRPHA	PROSER1	196	Q86XN7
PLPIPLRHKVPYPET	DCLRE1C	396	Q96SD1
PALPPKPYHPRLPAL	DOCK3	1971	Q8IZD9
PLHHPPGKLPEPQFY	EPHA8	596	P29322
PIRAAIPLHPPYHPS	CEP95	256	Q96GE4
IPLHPPYHPSEPRAP	CEP95	261	Q96GE4
HYKIPYPRPIHLPPM	LYRM1	76	O43325
ALHGYLRPKPPRPKP	HES7	121	Q9BYE0
FPHPAPYPHKERLPA	FEZF2	226	Q8TBJ5
APREIPLYLPHHPKP	MICAL2	1336	O94851
LPIVDSLHPRPPYLP	FUT8	291	Q9BYC5
RDPIPYLPPLEKLPH	SNRNP70	16	P08621
SPHFRHLPPYPLPKA	DROSHA	201	Q9NRR4
HLPPYPLPKAPSERR	DROSHA	206	Q9NRR4
DHRHLKPATPPYPMP	STARD9	3396	Q9P2P6
RIPDPPKHEHYPTPS	MRPL49	56	Q13405
PRHFLPHPGPIPKHL	ZNF750	281	Q32MQ0
RPPPYHPKQKRFPHR	MRPL38	346	Q96DV4
KLPYLPHPARPLHPA	TPRN	471	Q4KMQ1
VHVREKPLPHPPSLY	ZKSCAN2	936	Q63HK3
PSPPHHPELLYKPSP	ZNF438	161	Q7Z4V0