Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of brain-derived neurotrophic factor-activated receptor activity

FAM72D FAM72C FAM72A

1.11e-084303GO:0031551
GeneOntologyBiologicalProcessnegative regulation of brain-derived neurotrophic factor receptor signaling pathway

FAM72D FAM72C FAM72A

2.77e-085303GO:0031549
GeneOntologyBiologicalProcessregulation of brain-derived neurotrophic factor receptor signaling pathway

FAM72D FAM72C FAM72A

9.68e-087303GO:0031548
GeneOntologyBiologicalProcessbrain-derived neurotrophic factor receptor signaling pathway

FAM72D FAM72C FAM72A

1.00e-0614303GO:0031547
GeneOntologyBiologicalProcessnegative regulation of protein tyrosine kinase activity

FAM72D FAM72C FAM72A

1.10e-0530303GO:0061099
GeneOntologyBiologicalProcessnegative regulation of signaling receptor activity

FAM72D FAM72C FAM72A

1.47e-0533303GO:2000272
GeneOntologyBiologicalProcessnegative regulation of peptidyl-tyrosine phosphorylation

FAM72D FAM72C FAM72A

8.54e-0559303GO:0050732
GeneOntologyBiologicalProcessregulation of protein tyrosine kinase activity

FAM72D FAM72C FAM72A

1.36e-0469303GO:0061097
MousePhenoabnormal somatic hypermutation frequency

FAM72D FAM72C FAM72A

4.23e-0619243MP:0004815
MousePhenoabnormal class switch recombination

RAG1 FAM72D FAM72C FAM72A

1.02e-0581244MP:0004816
MousePhenokidney cyst

FAM72D FAM72C PRICKLE1 WDPCP FAM72A

1.08e-05177245MP:0003675
MousePhenoincreased B cell apoptosis

FAM72D FAM72C FAM72A

1.42e-0528243MP:0008782
MousePhenoincreased germinal center B cell number

FAM72D FAM72C FAM72A

1.94e-0531243MP:0008177
MousePhenoabnormal B cell apoptosis

FAM72D FAM72C FAM72A

6.86e-0547243MP:0008781
MousePhenoabnormal germinal center B cell number

FAM72D FAM72C FAM72A

1.10e-0455243MP:0013680
MousePhenoabnormal germinal center B cell morphology

FAM72D FAM72C FAM72A

1.10e-0455243MP:0008176
MousePhenoabnormal cyst

FAM72D FAM72C PRICKLE1 WDPCP FAM72A

1.22e-04294245MP:0031310
DomainFAM72

FAM72D FAM72C FAM72A

1.21e-084283PF14976
DomainFAM72

FAM72D FAM72C FAM72A

1.21e-084283IPR026768
DomainLIM

PRICKLE1 PDLIM7 FHL5

1.48e-0469283PF00412
Domain-

PRICKLE1 PDLIM7 FHL5

1.54e-04702832.10.110.10
DomainLIM_DOMAIN_2

PRICKLE1 PDLIM7 FHL5

1.61e-0471283PS50023
DomainZnf_LIM

PRICKLE1 PDLIM7 FHL5

1.61e-0471283IPR001781
DomainLIM_DOMAIN_1

PRICKLE1 PDLIM7 FHL5

1.61e-0471283PS00478
DomainLIM

PRICKLE1 PDLIM7 FHL5

1.61e-0471283SM00132
Domain-

RAG1 RNF7 TRIM21 PYGO1

4.27e-034492843.30.40.10
Domainzf-C3HC4

RAG1 RNF7 TRIM21

4.41e-03223283PF00097
DomainZnf_RING/FYVE/PHD

RAG1 RNF7 TRIM21 PYGO1

4.62e-03459284IPR013083
DomainButyrophylin

FSD2 TRIM21

4.91e-0370282IPR003879
DomainSPRY

FSD2 TRIM21

7.49e-0387282SM00449
DomainSPRY

FSD2 TRIM21

8.70e-0394282PF00622
DomainSPRY_dom

FSD2 TRIM21

8.70e-0394282IPR003877
DomainB30.2/SPRY

FSD2 TRIM21

8.88e-0395282IPR001870
DomainB302_SPRY

FSD2 TRIM21

8.88e-0395282PS50188
DomainZF_RING_2

RAG1 RNF7 TRIM21

9.81e-03298283PS50089
DomainRING

RAG1 RNF7 TRIM21

1.04e-02305283SM00184
DomainZnf_RING

RAG1 RNF7 TRIM21

1.25e-02326283IPR001841
Pubmed

Fam72a enforces error-prone DNA repair during antibody diversification.

FAM72D FAM72C FAM72A

2.56e-09431334819671
Pubmed

Identification and characterisation of the novel amyloid-beta peptide-induced protein p17.

FAM72D FAM72C FAM72A

6.40e-09531319755123
Pubmed

All-or-(N)One - an epistemological characterization of the human tumorigenic neuronal paralogous FAM72 gene loci.

FAM72D FAM72C FAM72A

6.40e-09531326206078
Pubmed

FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.

FAM72D FAM72C FAM72A

1.28e-08631334819670
Pubmed

cDNA sequence of a growth factor-inducible immediate early gene and characterization of its encoded protein.

FAM72D FAM72C FAM72A

2.90e-07153131741163
Pubmed

Sequential ubiquitination of NLRP3 by RNF125 and Cbl-b limits inflammasome activation and endotoxemia.

RAG1 TRIM21

4.21e-051131231999304
Pubmed

Microarray analysis of Myf5-/-:MyoD-/- hypoplastic mouse lungs reveals a profile of genes involved in pneumocyte differentiation.

RAG1 MYF5

5.96e-051331217330803
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R asymmetry by the mouse node.

MYF5 WNT2

1.45e-042031211440720
Pubmed

Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node.

MYF5 WNT2

1.45e-042031211517919
Pubmed

Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.

RAG1 TRIM21 ZBTB48

2.53e-0413831328786561
Pubmed

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.

SLC32A1 TRPM3

3.08e-042931228344592
Pubmed

Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5.

MYF5 TRPM3

3.08e-042931229543863
Pubmed

Deltex3 inhibits Epithelial Mesenchymal Transition in Papillary Thyroid Carcinoma via promoting ubiquitination of XRCC5 to regulate the AKT signal pathway.

TRIM21 MYO5A

7.77e-044631233403043
Pubmed

HOXA5 plays tissue-specific roles in the developing respiratory system.

MYF5 WNT2

7.77e-044631228827394
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

PRICKLE1 WNT2

8.11e-044731233141892
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

HRH1 MYF5 TRIM21 HIP1 KCNK17 ZBTB48

8.65e-04129331615342556
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

MYF5 TRPM3 PYGO1

8.85e-0421231319521566
Cytoband20q11.23

SLC32A1 KIAA1755

2.90e-043731220q11.23
CytobandEnsembl 112 genes in cytogenetic band chr15q21

MYO5A PYGO1

6.39e-03177312chr15q21
GeneFamilyLIM domain containing

PRICKLE1 PDLIM7 FHL5

4.86e-05592231218
GeneFamilyRing finger proteins

RAG1 RNF7 TRIM21

4.33e-0327522358
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

HIP1 KCNK17 ADAMTS4 FHL5

8.33e-06187314406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

HIP1 KCNK17 ADAMTS4 FHL5

9.63e-061943143892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNK17 ADAMTS4 PDLIM7 FHL5

1.00e-051963148c25fa61c117a60ddd4cbd2f95ae5b66f986a1ec
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

HIP1 KCNK17 PDLIM7 FHL5

1.00e-05196314754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KCNK17 ADAMTS4 TRPM3 FHL5

1.04e-05198314882710bd6215e299257dd3df234292db9a2823ba
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KCNK17 ADAMTS4 PDLIM7 FHL5

1.09e-05200314600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KCNK17 ADAMTS4 PDLIM7 FHL5

1.09e-05200314d70bad979299615fcba707ba21296020918705e6
ToppCellTracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KCNK17 ADAMTS4 PDLIM7 FHL5

1.09e-052003148158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCelldistal-mesenchymal-Airway_Smooth_Muscle-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

KCNK17 ADAMTS4 PDLIM7 FHL5

1.09e-05200314c69173892d80b8592233928cb207a3f4b533b4b4
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

KCNK17 ADAMTS4 PDLIM7 FHL5

1.09e-0520031438c21ec379005f688df33aea65237a063c476c2e
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 PDLIM7 FHL5

1.09e-04134313bffd6ce8998368d4f486b64c220eab3a44ba147b
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HIP1 PRICKLE1 WNT2

1.17e-0413731312caa8ed7cc9e7a0f78c14ad5efe2fc28c3ce9be
ToppCell10x5'-bone_marrow-Myeloid_Monocytic-Cycling_mono|bone_marrow / Manually curated celltypes from each tissue

FAM72D HIP1 PDLIM7

1.47e-04148313de35eeefad0e27a0d127e2e4bedead2bddb75152
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HRH1 PDLIM7 FAM72A

1.47e-04148313065177aaa63c0441d312260b43ecdac78c84ad03
ToppCellFetal_29-31_weeks-Mesenchymal-chondrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAG1 TRMT44 ADAMTS4

1.62e-0415331365641cc82883716dba0fefb749a30174a63f4da5
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

KIAA1755 ADAMTS4 PRICKLE1

1.68e-04155313e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1755 FAM72D PDLIM7

1.71e-04156313363f1b661048d25895e2b8681c82894c957b29c0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1755 FAM72D PDLIM7

1.71e-04156313d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-6|TCGA-Kidney / Sample_Type by Project: Shred V9

FAM72D FAM72C FAM72A

1.71e-04156313d249747c7108a0edfc72d24c09b0b0e4ed662b40
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal|GW19 / Sample Type, Dataset, Time_group, and Cell type.

FSD2 TRPM3 INSIG1

1.81e-04159313f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIAA1755 TRMT44 ADAMTS4

1.81e-041593137ed659163f45e0c4df4782997c0786900c8186c8
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell|GW19 / Sample Type, Dataset, Time_group, and Cell type.

FSD2 TRPM3 INSIG1

1.81e-04159313929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HIP1 PDLIM7 FHL5

1.84e-0416031329c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

HIP1 PDLIM7 FHL5

1.88e-0416131347b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellIonocyte-iono-3|World / Class top

HIP1 TRMT44 MYO5A

2.05e-041663139c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCellmild_COVID-19_(asymptomatic)-pDC|World / disease group, cell group and cell class (v2)

SLC32A1 FSD2 KCNK17

2.09e-04167313bf08f17965a4dd03f371b4ed0ab0d5e62ed61307
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-pDC|lymph-node_spleen / Manually curated celltypes from each tissue

SLC32A1 HIP1 KCNK17

2.13e-04168313cfed36fece51871a5abbcde71f6bd5e7212357ff
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HIP1 PRICKLE1 PDLIM7

2.17e-0416931341ad349806b279fbe1374b7e3cc7f146a11adb44
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HIP1 PRICKLE1 PDLIM7

2.17e-0416931342782c61592742190ab0cba8a94f8bdf9c278f90
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS4 PDLIM7 FHL5

2.20e-04170313fa753cc8fbd04e63c9a303da4dc17ee2ce907f92
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS4 PDLIM7 FHL5

2.20e-0417031303044e1436443b28dd39d5ef4fdb25c18e3a7546
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SLC32A1 KCNK17 ADAMTS4

2.24e-041713131f8e66073088fc1969782e443bf00f8c1877ea91
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

HIP1 PDLIM7 FHL5

2.24e-04171313e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellControl-Stromal-Pericyte|Control / Disease state, Lineage and Cell class

KCNK17 ADAMTS4 FHL5

2.36e-0417431391fc1f1c891f105a91968c22e2de5321c52b439a
ToppCellB_cells-pDCs|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

HIP1 KCNK17 ADAMTS4

2.44e-04176313ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KIAA1755 ADAMTS4 PRICKLE1

2.48e-041773133d955ea938a1d2fb1b6d68d4997fd454bd632dfc
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRICKLE1 WNT2 FHL5

2.48e-041773137af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

HIP1 ADAMTS4 FHL5

2.56e-04179313a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNK17 ADAMTS4 FHL5

2.56e-04179313dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HRH1 ZNF57 ADAMTS4

2.61e-0418031340d4838a0ccb10d5e49266bc8a0037d27b75ccc2
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HRH1 TRIM21 ADAMTS4

2.61e-04180313455d1e3ccf2ab609954f3b870e8f514ddca735f4
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS4 PRICKLE1 WNT2

2.61e-0418031312537d8a569faa69f474284d2c201475722b8ca1
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KIAA1755 KCNK17 ADAMTS4

2.65e-04181313b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 TRPM3 PRICKLE1

2.65e-04181313c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellmetastatic_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

SLC32A1 KCNK17 ADAMTS4

2.69e-0418231302e04294fce12591c32d7bd0e866a000ad1f836e
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

HIP1 PDLIM7 FHL5

2.74e-04183313818fd886e0188091310825f9145fa53328f2c979
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KIAA1755 PRICKLE1 PDLIM7

2.74e-04183313e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

KCNK17 ADAMTS4 FHL5

2.74e-04183313a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5|TCGA-Liver / Sample_Type by Project: Shred V9

FAM72D FAM72C FAM72A

2.74e-04183313f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

KCNK17 PDLIM7 FHL5

2.74e-04183313fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HIP1 PDLIM7 FHL5

2.74e-04183313cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.78e-04184313f6d6b3ddada66dae28d3306415bf4efe0934208a
ToppCellCOPD-Stromal-Pericyte|COPD / Disease state, Lineage and Cell class

KCNK17 ADAMTS4 FHL5

2.78e-04184313a56264a22dfc2d3672b20134ab7c3c7c23da5ae1
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

MYO5A FHL5 PYGO1

2.78e-0418431367164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

KCNK17 ADAMTS4 FHL5

2.82e-041853134905adaeeffd353e089578e5ea614437dbe794e6
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 ADAMTS4 FHL5

2.82e-0418531351dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAG1 ADAMTS4 FHL5

2.82e-04185313e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAG1 ADAMTS4 FHL5

2.82e-041853139d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.82e-041853131d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HIP1 ADAMTS4 FHL5

2.82e-04185313a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.82e-04185313b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.87e-0418631390eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCellCOPD-Stromal-Pericyte|World / Disease state, Lineage and Cell class

KCNK17 ADAMTS4 FHL5

2.87e-041863138adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FAM72D FAM72A NLRP13

2.87e-0418631386d145f965c311189e7996390eef491642417c5c
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.87e-04186313bd8a9753df219084e19e7f94447856e86608325c
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.92e-04187313b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.92e-04187313f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

KCNK17 PDLIM7 FHL5

2.92e-0418731362759efb660179402fb574ce5701c89a2e17bcfe
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.96e-04188313b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.96e-0418831314072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.96e-0418831360242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCellIPF-Stromal-SMC|World / Disease state, Lineage and Cell class

KCNK17 ADAMTS4 FHL5

2.96e-04188313b66264e8f8d536ed2beec31e6746c687718f239b
ToppCell3'_v3-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

SLC32A1 KCNK17 INSIG1

2.96e-04188313239a2162a21d3339da7c1884ab76286346fbf97f
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

2.96e-04188313d9692b6048d9b85524a07a1807bdd4757731c151
ToppCellIPF-Stromal-SMC|IPF / Disease state, Lineage and Cell class

KCNK17 ADAMTS4 FHL5

2.96e-04188313e98b24c0de41285f01f7ac194ff0a1b59fd5c333
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KIAA1755 PRICKLE1 PDLIM7

2.96e-041883133004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HIP1 PDLIM7 FHL5

3.01e-041893136b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

3.01e-0418931370eea8c94fa56bb15bee8065de47acea156794e9
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KIAA1755 HIP1 ADAMTS4

3.01e-04189313b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1755 PDLIM7 FHL5

3.05e-0419031370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellCOVID-19-Heart-EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

HIP1 ADAMTS4 FHL5

3.05e-04190313a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KCNK17 ADAMTS4 FHL5

3.05e-041903134eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KCNK17 ADAMTS4 FHL5

3.05e-041903137be4341e2909101d756f14031c21e705eb45e69a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1755 PRICKLE1 PDLIM7

3.10e-04191313107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIAA1755 PRICKLE1 PDLIM7

3.10e-04191313bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellwk_20-22-Hematologic-Myeloid-Cycling_DC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FAM72D FAM72C FAM72A

3.10e-041913131da569ebcfab4e1a95315430ae77a17a1f119263
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRH1 HIP1 ADAMTS4

3.15e-04192313945153c41dde6e90d103206955e1707b54eb0665
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRH1 HIP1 ADAMTS4

3.15e-041923136ab50579c63f31ca2cd41063a99b129f11c07510
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA1755 ADAMTS4 WNT2

3.15e-04192313df1545670370fb1010c567cd059c2783eab315f7
ToppCellFetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HRH1 MYO5A INSIG1

3.20e-041933132d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-Pericytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 PDLIM7 FHL5

3.20e-041933137631bf3362b4fa061ffeab4879ab12c4708dc4c0
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 PDLIM7 FHL5

3.20e-041933138d15c63f2ae48d0a00d7ef5fdafa917ab8ad0571
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNK17 ADAMTS4 FHL5

3.25e-041943138f19e553f18c313c2a2ff9453884b9484b255d71
ToppCellPCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

FAM72D TRPM3 FAM72A

3.25e-04194313c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNK17 ADAMTS4 FHL5

3.25e-04194313f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCellIPF-Stromal-Pericyte|World / Disease state, Lineage and Cell class

KCNK17 ADAMTS4 FHL5

3.25e-041943131a41da29d5adaf766a84eff0003b959e4523f7f1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KCNK17 PDLIM7 FHL5

3.25e-0419431367f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

KCNK17 ADAMTS4 FHL5

3.25e-0419431367fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

KCNK17 ADAMTS4 FHL5

3.25e-041943135e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HRH1 HIP1 ADAMTS4

3.30e-041953134db30b3bc65c25626f828cd4f867f20c71809898
Diseasetemporal lobe epilepsy (implicated_via_orthology)

SLC32A1 PRICKLE1

3.11e-059282DOID:3328 (implicated_via_orthology)
Diseaseheart conduction disease (implicated_via_orthology)

KCNK17 PYGO1

4.23e-0432282DOID:10273 (implicated_via_orthology)
Diseaseresponse to selective serotonin reuptake inhibitor

MTMR12 TRPM3

2.75e-0382282EFO_0005658
Diseasemigraine disorder, Headache

KCNK17 FHL5

3.02e-0386282HP_0002315, MONDO_0005277
Diseasevisual epilepsy (biomarker_via_orthology)

PRICKLE1 WNT2

3.30e-0390282DOID:11832 (biomarker_via_orthology)
Diseaseimmature platelet count

TRPM3 RTTN

4.55e-03106282EFO_0803544
Diseaseimmature platelet fraction

TRPM3 RTTN

5.24e-03114282EFO_0009187
Diseaseimmature platelet measurement

TRPM3 RTTN

5.69e-03119282EFO_0803541

Protein segments in the cluster

PeptideGeneStartEntry
NHSFHNCCMSLWVKQ

RNF7

81

Q9UBF6
CHNCWSIMHRKFSSA

RAG1

176

P15918
HHQAGHCLMWACKAC

MYF5

61

P13349
SCLLSCNNRHFWMFH

FAM72D

91

Q6L9T8
CWSCHNGSALLKMSA

MTMR12

266

Q9C0I1
LHRFCKRMTWFHMDC

KIAA1755

961

Q5JYT7
CCHHSSKEDFKSQSW

KCNK17

276

Q96T54
MPRLHDHFWSCSCAH

INSIG1

1

O15503
SCLLSCNNGHFWMFH

FAM72A

91

Q5TYM5
LCNWVRMAAAEHCHS

NPIPB7

211

O75200
LKMTWHVHCFTCAAC

PDLIM7

356

Q9NR12
WHMKHFCCLECETVL

PRICKLE1

211

Q96MT3
CHQMSFCLTELHLWS

WDPCP

31

O95876
WCSGHLNGHAMCQTK

ADAMTS4

471

O75173
HWHEGCFKCTKCNHS

FHL5

61

Q5TD97
SCLLSCNNRHFWMFH

FAM72C

91

H0Y354
CKNCCNEHLHMFTIW

HRH1

441

P35367
ASCQKWFHRICTGMT

PYGO1

361

Q9Y3Y4
LAKHWTAAIDMFCTC

RTTN

1766

Q86VV8
SEACKTRLCWFFMHH

TRMT44

711

Q8IYL2
RHCNSCMKTVAGSAW

RPL37AP8

56

A6NKH3
ANCLSWCMRHTFASS

FSD2

651

A1L4K1
SSNAVLCWKFCHVFH

HIP1

86

O00291
VFKAHWSVLACCSHF

ZBTB48

36

P10074
SHVTRMTKCGCKFHW

WNT2

316

P09544
FSHMTMIFQHLCCRW

TRPM3

1176

Q9HCF6
CWVCAQSRKHRDHAM

TRIM21

111

P19474
CKQCGMSFKWHSSFR

ZNF57

506

Q68EA5
FHCMMNWTHIAACVL

SLC32A1

336

Q9H598
SKFDSRMHAWNSICS

NLRP13

706

Q86W25
MCHWLCHRKLATATE

MYO5A

371

Q9Y4I1