Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled photoreceptor activity	OPN1MW2 OPN1MW3 OPN1MW	7.85e-06	15	53	3	GO:0008020
GeneOntologyMolecularFunction	photoreceptor activity	OPN1MW2 OPN1MW3 OPN1MW	1.17e-05	17	53	3	GO:0009881
GeneOntologyMolecularFunction	adiponectin binding	ADIPOR1 ADIPOR2	2.07e-05	3	53	2	GO:0055100
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OPN1MW2 OR51G2 OR51A4 OR51A2 GABRG1 OPN1MW3 OR2T6 TLR1 OR56A3 OPN1MW TLR6 CHRNB4 ADGRG6	3.92e-05	1353	53	13	GO:0004888
GeneOntologyMolecularFunction	adipokinetic hormone receptor activity	ADIPOR1 ADIPOR2	4.13e-05	4	53	2	GO:0097003
GeneOntologyMolecularFunction	Toll-like receptor 2 binding	TLR1 TLR6	4.13e-05	4	53	2	GO:0035663
GeneOntologyMolecularFunction	Toll-like receptor binding	DAB2IP TLR1 TLR6	6.14e-05	29	53	3	GO:0035325
GeneOntologyMolecularFunction	GTPase activator activity	DAB2IP RASA4 TBC1D7 RASA4B RASAL2 SYNGAP1	9.33e-05	279	53	6	GO:0005096
GeneOntologyMolecularFunction	lipopeptide binding	TLR1 TLR6	3.07e-04	10	53	2	GO:0071723
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DAB2IP PSD2 RASA4 TBC1D7 RASA4B RASAL2 SYNGAP1	3.66e-04	507	53	7	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DAB2IP PSD2 RASA4 TBC1D7 RASA4B RASAL2 SYNGAP1	3.66e-04	507	53	7	GO:0030695
GeneOntologyMolecularFunction	transporter activity	SLC6A4 GABRG1 SFXN4 CNNM4 ABCC3 SLC19A3 SLC13A3 SLC4A9 ATP10D CHRNB4 ITPR2	4.79e-04	1289	53	11	GO:0005215
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OPN1MW2 OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 OR56A3 OPN1MW ADGRG6	4.81e-04	884	53	9	GO:0004930
GeneOntologyMolecularFunction	sulfur compound transmembrane transporter activity	ABCC3 SLC19A3 SLC13A3	5.70e-04	61	53	3	GO:1901682
GeneOntologyMolecularFunction	NAD+ nucleotidase, cyclic ADP-ribose generating	TLR1 TLR6	8.10e-04	16	53	2	GO:0061809
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A4 GABRG1 SFXN4 CNNM4 ABCC3 SLC19A3 SLC13A3 SLC4A9 CHRNB4 ITPR2	9.50e-04	1180	53	10	GO:0022857
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A4 GABRG1 SFXN4 CNNM4 SLC13A3 SLC4A9 CHRNB4 ITPR2	1.09e-03	793	53	8	GO:0015075
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	SLC6A4 GABRG1 ABCC3 SLC4A9	1.10e-03	171	53	4	GO:0015103
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A4 CNNM4 SLC13A3 SLC4A9	1.10e-03	171	53	4	GO:0015081
GeneOntologyMolecularFunction	solute:sodium symporter activity	SLC6A4 SLC13A3 SLC4A9	1.30e-03	81	53	3	GO:0015370
GeneOntologyMolecularFunction	protein-hormone receptor activity	ADIPOR1 ADIPOR2	1.54e-03	22	53	2	GO:0016500
GeneOntologyMolecularFunction	enzyme activator activity	DAB2IP RASA4 TBC1D7 RASA4B GCN1 RASAL2 SYNGAP1	1.66e-03	656	53	7	GO:0008047
GeneOntologyMolecularFunction	modified amino acid transmembrane transporter activity	SLC19A3 SLC13A3	3.46e-03	33	53	2	GO:0072349
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A4 GABRG1 CNNM4 ABCC3 SLC13A3 SLC4A9 ITPR2	3.73e-03	758	53	7	GO:0015318
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A4 SLC13A3 SLC4A9	3.89e-03	119	53	3	GO:0015294
GeneOntologyMolecularFunction	lipid binding	DAB2IP PSD2 RASA4 TLR1 RASA4B TLR6 DBT ITPR2	4.27e-03	988	53	8	GO:0008289
GeneOntologyMolecularFunction	chloride transmembrane transporter activity	SLC6A4 GABRG1 SLC4A9	4.47e-03	125	53	3	GO:0015108
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing N-glycosyl compounds	TLR1 TLR6	5.30e-03	41	53	2	GO:0016799
GeneOntologyMolecularFunction	amide transmembrane transporter activity	SLC19A3 SLC13A3	5.56e-03	42	53	2	GO:0042887
GeneOntologyMolecularFunction	olfactory receptor activity	OR51G2 OR51A4 OR51A2 OR2T6 OR56A3	5.61e-03	431	53	5	GO:0004984
GeneOntologyMolecularFunction	symporter activity	SLC6A4 SLC13A3 SLC4A9	7.40e-03	150	53	3	GO:0015293
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	SLC6A4 GABRG1 SLC4A9	7.53e-03	151	53	3	GO:0008509
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	ABCC3 SLC19A3 SLC13A3 SLC4A9	7.57e-03	293	53	4	GO:0008514
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A4 CNNM4 SLC13A3 SLC4A9 ITPR2	7.68e-03	465	53	5	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A4 CNNM4 SLC13A3 SLC4A9 CHRNB4 ITPR2	8.05e-03	664	53	6	GO:0008324
GeneOntologyBiologicalProcess	negative regulation of Ras protein signal transduction	DAB2IP RASA4 RASA4B SYNGAP1	7.03e-07	28	52	4	GO:0046580
GeneOntologyBiologicalProcess	detection of stimulus	OPN1MW2 OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 TLR1 OR56A3 OPN1MW TLR6	1.08e-05	722	52	10	GO:0051606
GeneOntologyBiologicalProcess	regulation of Ras protein signal transduction	DAB2IP RASA4 RASA4B SYNGAP1	1.69e-05	61	52	4	GO:0046578
GeneOntologyBiologicalProcess	detection of bacterial lipopeptide	TLR1 TLR6	1.87e-05	3	52	2	GO:0070340
GeneOntologyBiologicalProcess	negative regulation of small GTPase mediated signal transduction	DAB2IP RASA4 RASA4B SYNGAP1	2.45e-05	67	52	4	GO:0051058
GeneOntologyBiologicalProcess	detection of bacterial lipoprotein	TLR1 TLR6	3.73e-05	4	52	2	GO:0042494
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A4 GABRG1 SFXN4 CNNM4 ABCC3 SLC13A3 RNASEK SLC4A9 ATP10D CHRNB4 ITPR2	8.56e-05	1115	52	11	GO:0034220
GeneOntologyBiologicalProcess	adiponectin-activated signaling pathway	ADIPOR1 ADIPOR2	1.30e-04	7	52	2	GO:0033211
GeneOntologyBiologicalProcess	cellular response to bacterial lipoprotein	TLR1 TLR6	2.77e-04	10	52	2	GO:0071220
GeneOntologyBiologicalProcess	cellular response to bacterial lipopeptide	TLR1 TLR6	2.77e-04	10	52	2	GO:0071221
GeneOntologyBiologicalProcess	response to bacterial lipopeptide	TLR1 TLR6	2.77e-04	10	52	2	GO:0070339
GeneOntologyBiologicalProcess	Ras protein signal transduction	DAB2IP RASA4 RASA4B SYNGAP1	3.04e-04	128	52	4	GO:0007265
GeneOntologyBiologicalProcess	cellular response to light stimulus	OPN1MW2 OPN1MW3 POLH OPN1MW	3.23e-04	130	52	4	GO:0071482
GeneOntologyBiologicalProcess	phototransduction	OPN1MW2 OPN1MW3 OPN1MW	3.24e-04	53	52	3	GO:0007602
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR51G2 OR51A4 OR51A2 OR2T6 TLR1 OR56A3 TLR6	3.26e-04	524	52	7	GO:0009593
GeneOntologyBiologicalProcess	response to bacterial lipoprotein	TLR1 TLR6	3.38e-04	11	52	2	GO:0032493
GeneOntologyBiologicalProcess	detection of visible light	OPN1MW2 OPN1MW3 OPN1MW	4.02e-04	57	52	3	GO:0009584
GeneOntologyBiologicalProcess	regulation of toll-like receptor 2 signaling pathway	TLR1 TLR6	4.78e-04	13	52	2	GO:0034135
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC6A4 GABRG1 SFXN4 CNNM4 ABCC3 SLC13A3 RNASEK SLC4A9 ATP10D CHRNB4 ITPR2	5.27e-04	1374	52	11	GO:0006811
GeneOntologyBiologicalProcess	detection of molecule of bacterial origin	TLR1 TLR6	7.31e-04	16	52	2	GO:0032490
GeneOntologyCellularComponent	photoreceptor disc membrane	OPN1MW2 OPN1MW3 OPN1MW	3.84e-05	26	53	3	GO:0097381
Domain	RasGAP	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	2.70e-10	14	52	5	SM00323
Domain	RasGAP_CS	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	2.70e-10	14	52	5	IPR023152
Domain	RAS_GTPASE_ACTIV_2	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	4.04e-10	15	52	5	PS50018
Domain	RasGAP	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	4.04e-10	15	52	5	PF00616
Domain	RAS_GTPASE_ACTIV_1	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	4.04e-10	15	52	5	PS00509
Domain	-	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	5.86e-10	16	52	5	1.10.506.10
Domain	RasGAP_dom	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	1.14e-09	18	52	5	IPR001936
Domain	DUF3498	DAB2IP RASAL2 SYNGAP1	2.04e-08	3	52	3	PF12004
Domain	DUF3498	DAB2IP RASAL2 SYNGAP1	2.04e-08	3	52	3	IPR021887
Domain	Rho_GTPase_activation_prot	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	4.52e-06	88	52	5	IPR008936
Domain	Opsin_red/grn	OPN1MW3 OPN1MW	2.28e-05	3	52	2	IPR000378
Domain	-	RASA4 RASA4B	2.28e-05	3	52	2	4.10.1130.10
Domain	C2	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	3.14e-05	131	52	5	PF00168
Domain	C2	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	3.89e-05	137	52	5	SM00239
Domain	C2	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	4.62e-05	142	52	5	PS50004
Domain	-	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	5.62e-05	148	52	5	2.60.40.150
Domain	Toll-like_receptor	TLR1 TLR6	7.56e-05	5	52	2	IPR017241
Domain	C2_dom	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	9.14e-05	164	52	5	IPR000008
Domain	PH	DAB2IP PSD2 RASA4 RASA4B RASAL2 SYNGAP1	1.18e-04	278	52	6	SM00233
Domain	PH_DOMAIN	DAB2IP PSD2 RASA4 RASA4B RASAL2 SYNGAP1	1.20e-04	279	52	6	PS50003
Domain	PH_domain	DAB2IP PSD2 RASA4 RASA4B RASAL2 SYNGAP1	1.23e-04	280	52	6	IPR001849
Domain	BTK	RASA4 RASA4B	2.70e-04	9	52	2	SM00107
Domain	ZF_BTK	RASA4 RASA4B	2.70e-04	9	52	2	PS51113
Domain	Znf_Btk_motif	RASA4 RASA4B	2.70e-04	9	52	2	IPR001562
Domain	BTK	RASA4 RASA4B	2.70e-04	9	52	2	PF00779
Domain	OPSIN	OPN1MW3 OPN1MW	3.37e-04	10	52	2	PS00238
Domain	AdipoR/HlyIII-related	ADIPOR1 ADIPOR2	4.11e-04	11	52	2	IPR004254
Domain	Opsin	OPN1MW3 OPN1MW	4.11e-04	11	52	2	IPR001760
Domain	HlyIII	ADIPOR1 ADIPOR2	4.11e-04	11	52	2	PF03006
Domain	-	DAB2IP PSD2 RASA4 RASA4B RASAL2 SYNGAP1	7.31e-04	391	52	6	2.30.29.30
Domain	PH_dom-like	DAB2IP PSD2 RASA4 RASA4B RASAL2 SYNGAP1	1.14e-03	426	52	6	IPR011993
Domain	TIR	TLR1 TLR6	1.54e-03	21	52	2	SM00255
Domain	TIR	TLR1 TLR6	1.69e-03	22	52	2	PF01582
Domain	-	TLR1 TLR6	1.85e-03	23	52	2	3.40.50.10140
Domain	TIR	TLR1 TLR6	2.02e-03	24	52	2	PS50104
Domain	TIR_dom	TLR1 TLR6	2.19e-03	25	52	2	IPR000157
Domain	GPCR_Rhodpsn_7TM	OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 OR56A3 OPN1MW	2.44e-03	670	52	7	IPR017452
Domain	HECT	UBE3B TRIP12	2.55e-03	27	52	2	PF00632
Domain	HECTc	UBE3B TRIP12	2.55e-03	27	52	2	SM00119
Domain	HECT_dom	UBE3B TRIP12	2.55e-03	27	52	2	IPR000569
Domain	HECT	UBE3B TRIP12	2.55e-03	27	52	2	PS50237
Domain	7tm_1	OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 OR56A3 OPN1MW	2.58e-03	677	52	7	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 OR56A3 OPN1MW	2.76e-03	685	52	7	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 OR56A3 OPN1MW	2.89e-03	691	52	7	PS50262
Domain	GPCR_Rhodpsn	OR51G2 OR51A4 OR51A2 OPN1MW3 OR2T6 OR56A3 OPN1MW	2.92e-03	692	52	7	IPR000276
Domain	LRRCT	TLR1 TLR6	3.57e-03	32	52	2	PF01463
Domain	7TM_GPCR_Srsx	OR51A4 OR51A2 OPN1MW3	3.75e-03	112	52	3	SM01381
Domain	PH	PSD2 RASA4 RASA4B SYNGAP1	3.76e-03	229	52	4	PF00169
Domain	Olfact_rcpt	OR51G2 OR51A4 OR51A2 OR2T6 OR56A3	4.64e-03	393	52	5	IPR000725
Domain	Neurotransmitter_ion_chnl_CS	GABRG1 CHRNB4	6.97e-03	45	52	2	IPR018000
Domain	Neur_chan_memb	GABRG1 CHRNB4	7.28e-03	46	52	2	PF02932
Domain	Neur_chan_LBD	GABRG1 CHRNB4	7.59e-03	47	52	2	PF02931
Domain	Neur_channel	GABRG1 CHRNB4	7.59e-03	47	52	2	IPR006201
Domain	Neur_chan_lig-bd	GABRG1 CHRNB4	7.59e-03	47	52	2	IPR006202
Domain	NEUROTR_ION_CHANNEL	GABRG1 CHRNB4	7.59e-03	47	52	2	PS00236
Domain	Neurotrans-gated_channel_TM	GABRG1 CHRNB4	7.59e-03	47	52	2	IPR006029
Domain	-	GABRG1 CHRNB4	7.59e-03	47	52	2	2.70.170.10
Pathway	REACTOME_REGULATION_OF_RAS_BY_GAPS	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	2.28e-06	66	46	5	MM15261
Pathway	REACTOME_REGULATION_OF_RAS_BY_GAPS	DAB2IP RASA4 RASAL2 SYNGAP1	6.94e-05	68	46	4	M27539
Pathway	PID_RAS_PATHWAY	DAB2IP RASA4 SYNGAP1	1.24e-04	30	46	3	M269
Pathway	REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY	ADIPOR1 ADIPOR2	1.55e-04	6	46	2	MM14630
Pathway	REACTOME_AMPK_INHIBITS_CHREBP_TRANSCRIPTIONAL_ACTIVATION_ACTIVITY	ADIPOR1 ADIPOR2	2.88e-04	8	46	2	M26990
Pathway	REACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION	OPN1MW2 OPN1MW3	2.88e-04	8	46	2	MM14880
Pathway	WP_RAS_SIGNALING	PLA1A RASA4 RASA4B RASAL2 SYNGAP1	3.19e-04	184	46	5	M39764
Pathway	WP_LEPTIN_AND_ADIPONECTIN	ADIPOR1 ADIPOR2	4.61e-04	10	46	2	M39539
Pathway	REACTOME_OPSINS	OPN1MW2 OPN1MW3	4.61e-04	10	46	2	MM15063
Pathway	WP_LEPTIN_AND_ADIPONECTIN	ADIPOR1 ADIPOR2	4.61e-04	10	46	2	MM15824
Pubmed	Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.	OPN1MW2 OPN1MW3 OPN1MW	1.34e-08	4	53	3	29386880
Pubmed	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.	OPN1MW2 OPN1MW3 OPN1MW	3.33e-08	5	53	3	2937147
Pubmed	Adiponectin receptor-1 expression is decreased in the pancreas of obese mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19062045
Pubmed	Cardiomyocyte-derived adiponectin is biologically active in protecting against myocardial ischemia-reperfusion injury.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	20028965
Pubmed	Lack of any prognostic relationship between adiponectin receptor (Adipo R1/R2) expression for early/advanced stage gastric cancer.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	24969908
Pubmed	Species-specific recognition of Aspergillus fumigatus by Toll-like receptor 1 and Toll-like receptor 6.	TLR1 TLR6	2.28e-06	2	53	2	22315281
Pubmed	Adiponectin and adiponectin receptor in relation to colorectal cancer progression.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	21351255
Pubmed	Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.	OPN1MW2 OPN1MW	2.28e-06	2	53	2	28402104
Pubmed	Role of TLR1 and TLR6 in the host defense against disseminated candidiasis.	TLR1 TLR6	2.28e-06	2	53	2	18036178
Pubmed	Arterial stiffness is associated with increased monocyte expression of adiponectin receptor mRNA and protein in patients with coronary artery disease.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	22534793
Pubmed	Regulation of multidrug resistance-associated protein 2 by calcium signaling in mouse liver.	ABCC3 ITPR2	2.28e-06	2	53	2	20578149
Pubmed	Expression of adiponectin receptor mRNA in human skeletal muscle cells is related to in vivo parameters of glucose and lipid metabolism.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15331527
Pubmed	Omental fat expression of adiponectin and adiponectin receptors in non-obese women with PCOS: a preliminary study.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19909601
Pubmed	The role of AdipoR1 and AdipoR2 in liver fibrosis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	29237572
Pubmed	Variations in adiponectin receptor genes and susceptibility to type 2 diabetes in women: a tagging-single nucleotide polymorphism haplotype analysis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17416799
Pubmed	Muscle-specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	28145500
Pubmed	AdipoR agonist increases insulin sensitivity and exercise endurance in AdipoR-humanized mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	33420419
Pubmed	The association of genetic variants in toll-like receptor 2 subfamily with allergy and asthma after hospitalization for bronchiolitis in infancy.	TLR1 TLR6	2.28e-06	2	53	2	24445834
Pubmed	Adiponectin receptor expression predicts favorable prognosis in cases of hepatocellular carcinoma.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	24619866
Pubmed	[DISTRIBUTION OF TWO-LOCUS HAPLOTYPES OF MICROBIAL COMPONENT SENSOR GENES TLR1 AND TLR6 IN MAJOR POPULATIONS OF SOUTH URALS].	TLR1 TLR6	2.28e-06	2	53	2	26470427
Pubmed	Defective colour vision associated with a missense mutation in the human green visual pigment gene.	OPN1MW2 OPN1MW	2.28e-06	2	53	2	1302020
Pubmed	Overexpression of adiponectin receptors potentiates the antiinflammatory action of subeffective dose of globular adiponectin in vascular endothelial cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18988888
Pubmed	Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19549705
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	2.28e-06	2	53	2	11448776
Pubmed	Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants.	TLR1 TLR6	2.28e-06	2	53	2	21852947
Pubmed	Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25392268
Pubmed	Pattern of expression of adiponectin receptors in human liver and its relation to nonalcoholic steatohepatitis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18923878
Pubmed	Toll-like Receptor 1 743 A>G, 1805 T>G & Toll-like Receptor 6 745 C>T gene polymorphism and tuberculosis: a case control study of north Indian population from Agra (India).	TLR1 TLR6	2.28e-06	2	53	2	24984237
Pubmed	Absence of an association between the polymorphisms in the genes encoding adiponectin receptors and type 2 diabetes.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15918014
Pubmed	The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18842004
Pubmed	Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.	OPN1MW2 OPN1MW	2.28e-06	2	53	2	10319869
Pubmed	Adiponectin receptor genes: mutation screening in syndromes of insulin resistance and association studies for type 2 diabetes and metabolic traits in UK populations.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17216283
Pubmed	Dual action of adiponectin on insulin secretion in insulin-resistant mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15358228
Pubmed	Loss of RasGAP Tumor Suppressors Underlies the Aggressive Nature of Luminal B Breast Cancers.	DAB2IP RASAL2	2.28e-06	2	53	2	27974415
Pubmed	Regulation of adiponectin receptor gene expression in diabetic mice.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15613685
Pubmed	Association of sequence variations in the gene encoding adiponectin receptor 1 (ADIPOR1) with body size and insulin levels. The Finnish Diabetes Prevention Study.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16724230
Pubmed	Demonstration of adiponectin receptors 1 and 2 mRNA expression in human breast cancer cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17123704
Pubmed	Cutting edge: functional interactions between toll-like receptor (TLR) 2 and TLR1 or TLR6 in response to phenol-soluble modulin.	TLR1 TLR6	2.28e-06	2	53	2	11123271
Pubmed	AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	30890562
Pubmed	SNPs in the exons of Toll-like receptors are associated with susceptibility to type 1 diabetes in Chinese population.	TLR1 TLR6	2.28e-06	2	53	2	25261617
Pubmed	The regulation of adiponectin receptors in human prostate cancer cell lines.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16899222
Pubmed	Polymorphisms in adiponectin receptor genes are associated with lipodystrophy-related phenotypes in HIV-infected patients receiving antiretroviral therapy.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	26111083
Pubmed	Upregulation of adiponectin receptor 1 and 2 mRNA and protein in adipose tissue and adipocytes in insulin-resistant women with polycystic ovary syndrome.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17001470
Pubmed	Association of Adiponectin Receptors with Metabolic and Immune Homeostasis Parameters in Colorectal Cancer: In Silico Analysis and Observational Findings.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	36429712
Pubmed	Expression of adiponectin receptors in mouse adrenal glands and the adrenocortical Y-1 cell line: adiponectin regulates steroidogenesis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19878661
Pubmed	Genetic ancestry effects on the distribution of toll-like receptors (TLRs) gene polymorphisms in a population of the Atlantic Forest, São Paulo, Brazil.	TLR1 TLR6	2.28e-06	2	53	2	29175392
Pubmed	Variations in ADIPOR1 But Not ADIPOR2 are Associated With Hypertriglyceridemia and Diabetes in an Admixed Latin American Population.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	29145541
Pubmed	AdipoR-increased intracellular ROS promotes cPLA2 and COX-2 expressions via activation of PKC and p300 in adiponectin-stimulated human alveolar type II cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	27288489
Pubmed	Adiponectin receptor expression in gastric carcinoma: implications in tumor development and progression.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	23358721
Pubmed	Expression profiles of adiponectin receptors in mouse embryos.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15939384
Pubmed	Expression and biologic significance of adiponectin receptors in papillary thyroid carcinoma.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	22907586
Pubmed	Characterisation of the adiponectin receptors: Differential cell-surface expression and temporal signalling profiles of AdipoR1 and AdipoR2 are regulated by the non-conserved N-terminal trunks.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25892445
Pubmed	Adiponectin receptors form homomers and heteromers exhibiting distinct ligand binding and intracellular signaling properties.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	23255609
Pubmed	Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17716299
Pubmed	Low-abundant adiponectin receptors in visceral adipose tissue of humans and rats are further reduced in diabetic animals.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	20470935
Pubmed	Adipo-R1 and adipo-R2 expression in colorectal adenomas and carcinomas.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25640382
Pubmed	The expression and relationship of AdipoR1/R2 in gastric intestinal metaplasia.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	33851685
Pubmed	Adiponectin inhibits the growth and peritoneal metastasis of gastric cancer through its specific membrane receptors AdipoR1 and AdipoR2.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17459059
Pubmed	Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18310295
Pubmed	The effect of renal transplantation on adiponectin and its isoforms and receptors.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17697862
Pubmed	Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	21186369
Pubmed	The Roles of TLR Gene Polymorphisms in Atherosclerosis: A Systematic Review and Meta-Analysis of 35,317 Subjects.	TLR1 TLR6	2.28e-06	2	53	2	28474755
Pubmed	Expressions of adiponectin receptors in placenta and their correlation with preeclampsia.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19487733
Pubmed	Polymorphisms of ADIPOR1 and ADIPOR2 are associated with phenotypes of type 2 diabetes in Koreans.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18466348
Pubmed	Association of ADIPOR2 with liver function tests in type 2 diabetic subjects.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18719649
Pubmed	Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	18971219
Pubmed	Crystal structures of the human adiponectin receptors.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25855295
Pubmed	Adiponectin receptor signaling on dendritic cells blunts antitumor immunity.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25261236
Pubmed	Adiponectin receptors gene expression and insulin sensitivity in non-diabetic Mexican Americans with or without a family history of Type 2 diabetes.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15105989
Pubmed	Adiponectin receptors are downregulated in human gastric cancer.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	20336470
Pubmed	Opposing effects of adiponectin receptors 1 and 2 on energy metabolism.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17327425
Pubmed	Divergent roles for adiponectin receptor 1 (AdipoR1) and AdipoR2 in mediating revascularization and metabolic dysfunction in vivo.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	24742672
Pubmed	Structural insights into adiponectin receptors suggest ceramidase activity.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	28329765
Pubmed	Localization of novel adiponectin receptor constructs.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17118803
Pubmed	in vitro Anti-Proliferative Effect of Adiponectin on Human Endometriotic Stromal Cells through AdipoR1 and AdipoR2 Gene Receptor Expression.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	26459399
Pubmed	Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16205883
Pubmed	Genetic variants of adiponectin receptor 2 are associated with increased adiponectin levels and decreased triglyceride/VLDL levels in patients with metabolic syndrome.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16700915
Pubmed	A monoclonal antibody activating AdipoR for type 2 diabetes and nonalcoholic steatohepatitis.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	37948516
Pubmed	Expression of adiponectin receptors and its possible implication in the human endometrium.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16601138
Pubmed	AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	22000082
Pubmed	Adiponectin regulate growth hormone secretion via adiponectin receptor mediated Ca(2+) signalling in rat somatotrophs in vitro.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19500219
Pubmed	Gene expression of adiponectin receptors in human visceral and subcutaneous adipose tissue is related to insulin resistance and metabolic parameters and is altered in response to physical training.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	17878241
Pubmed	Regulation of adiponectin receptors in hepatocytes by the peroxisome proliferator-activated receptor-gamma agonist rosiglitazone.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16609881
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	2.28e-06	2	53	2	16041389
Pubmed	Myocardial mitochondrial dysfunction in mice lacking adiponectin receptor 1.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25982881
Pubmed	Genetic analysis of ADIPOR1 and ADIPOR2 candidate polymorphisms for type 2 diabetes in the Caucasian population.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	16505255
Pubmed	A specific role for TLR1 in protective T(H)17 immunity during mucosal infection.	TLR1 TLR6	2.28e-06	2	53	2	22778390
Pubmed	Expression, purification, crystallization, and preliminary X-ray crystallographic studies of the human adiponectin receptors, AdipoR1 and AdipoR2.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	25575462
Pubmed	The distribution of adiponectin receptors on human peripheral blood mononuclear cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19120283
Pubmed	Role of adiponectin receptors, AdipoR1 and AdipoR2, in the steroidogenesis of the human granulosa tumor cell line, KGN.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	19671624
Pubmed	Expression of adiponectin receptors in pancreatic beta cells.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	14651988
Pubmed	Leveraging a gain-of-function allele of Caenorhabditis elegans paqr-1 to elucidate membrane homeostasis by PAQR proteins.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	32750056
Pubmed	Genetic variation in adiponectin receptor 1 and adiponectin receptor 2 is associated with type 2 diabetes in the Old Order Amish.	ADIPOR1 ADIPOR2	2.28e-06	2	53	2	15983228
Pubmed	Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium.	OPN1MW2 TYRP1 OPN1MW3	4.36e-06	21	53	3	26876013
Pubmed	Adiponectin mediates antiproliferative and apoptotic responses in human MCF7 breast cancer cells.	ADIPOR1 ADIPOR2	6.83e-06	3	53	2	16678125
Pubmed	Identification of adiponectin and its receptors in human osteoblast-like cells and association of T45G polymorphism in exon 2 of adiponectin gene with lumbar spine bone mineral density in Korean women.	ADIPOR1 ADIPOR2	6.83e-06	3	53	2	17054465
Pubmed	Differential effects of adiponectin in osteoblast-like cells.	ADIPOR1 ADIPOR2	6.83e-06	3	53	2	24673523
Pubmed	Molecular determinants of human red/green color discrimination.	OPN1MW2 OPN1MW	6.83e-06	3	53	2	8185948
Pubmed	X-linked cone dystrophy caused by mutation of the red and green cone opsins.	OPN1MW2 OPN1MW	6.83e-06	3	53	2	20579627
Pubmed	The effects of exercise and adipose tissue lipolysis on plasma adiponectin concentration and adiponectin receptor expression in human skeletal muscle.	ADIPOR1 ADIPOR2	6.83e-06	3	53	2	15757860
Interaction	ANKS1B interactions	DAB2IP SLC6A4 RASAL2 SYNGAP1	1.14e-06	34	47	4	int:ANKS1B
Cytoband	11p15.4	OR51G2 OR51A4 OR51A2 OR56A3	8.66e-05	200	53	4	11p15.4
Cytoband	4p12	GABRG1 ATP10D	2.45e-04	20	53	2	4p12
Cytoband	Ensembl 112 genes in cytogenetic band chr4p12	GABRG1 ATP10D	4.18e-04	26	53	2	chr4p12
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51G2 OR51A4 OR51A2 CALCB OR56A3	4.85e-04	564	53	5	chr11p15
Cytoband	4p14	TLR1 TLR6	1.09e-03	42	53	2	4p14
Cytoband	Ensembl 112 genes in cytogenetic band chrXq28	OPN1MW2 OPN1MW3 OPN1MW	1.94e-03	213	53	3	chrXq28
Cytoband	Ensembl 112 genes in cytogenetic band chr4p14	TLR1 TLR6	2.76e-03	67	53	2	chr4p14
Cytoband	Ensembl 112 genes in cytogenetic band chr2q36	SLC19A3 TRIP12	4.39e-03	85	53	2	chr2q36
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	DAB2IP RASA4 RASA4B RASAL2 SYNGAP1	8.95e-12	10	39	5	830
GeneFamily	Opsin receptors	OPN1MW2 OPN1MW3 OPN1MW	1.51e-06	11	39	3	215
GeneFamily	Adiponectin receptors\|Progestin and adipoQ receptor family	ADIPOR1 ADIPOR2	4.53e-06	2	39	2	293
GeneFamily	Olfactory receptors, family 51	OR51G2 OR51A4 OR51A2	1.16e-04	44	39	3	164
GeneFamily	CD molecules\|Toll like receptors	TLR1 TLR6	2.02e-04	10	39	2	948
GeneFamily	Progestin and adipoQ receptor family	ADIPOR1 ADIPOR2	2.46e-04	11	39	2	930
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD2 RASA4B RASAL2	9.85e-03	206	39	3	682
GeneFamily	Solute carriers	SLC6A4 SLC19A3 SLC13A3 SLC4A9	1.01e-02	395	39	4	752
ToppCell	LAM-Endothelial-VasEndo-2\|Endothelial / Condition, Lineage and Cell class	SLC6A4 PLA1A RASA4 ADIPOR2 ADGRG6	3.13e-06	198	51	5	92bccaec01f1dbb17d5efcba30f7f800f674ca96
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SLC6A4 TYRP1 PLA1A RASA4 ADGRG6	3.21e-06	199	51	5	15db14eff63d5edeced0738542d5fb739225511b
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-8\|TCGA-Kidney / Sample_Type by Project: Shred V9	OR51G2 SLC19A3 CFAP61 CHRNB4	1.20e-05	123	51	4	967f20fcb27c9989de93f4183038334105910175
Disease	blue cone monochromacy (implicated_via_orthology)	OPN1MW2 OPN1MW3 OPN1MW	1.42e-08	4	46	3	DOID:0050679 (implicated_via_orthology)
Disease	end stage renal disease (biomarker_via_orthology)	ABCC3 ADIPOR1 ADIPOR2	5.48e-05	47	46	3	DOID:783 (biomarker_via_orthology)
Disease	developmental disorder of mental health (implicated_via_orthology)	DAB2IP RASAL2 SYNGAP1	6.21e-05	49	46	3	DOID:0060037 (implicated_via_orthology)
Disease	aspergillosis (is_implicated_in)	TLR1 TLR6	6.62e-05	8	46	2	DOID:13564 (is_implicated_in)
Disease	vitamin D measurement, vitamin D dietary intake measurement	CALCB BCAS1	6.62e-05	8	46	2	EFO_0004631, EFO_0008539
Disease	hyperinsulinism (biomarker_via_orthology)	ADIPOR1 ADIPOR2	2.46e-04	15	46	2	DOID:2018 (biomarker_via_orthology)
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TLR1 TLR6	3.19e-04	17	46	2	DOID:8677 (biomarker_via_orthology)
Disease	Subfertility, Female	ADIPOR1 ADIPOR2	8.76e-04	28	46	2	C0341869
Disease	Sterility, Postpartum	ADIPOR1 ADIPOR2	8.76e-04	28	46	2	C0038279
Disease	tuberculosis (is_implicated_in)	TLR1 TLR6	8.76e-04	28	46	2	DOID:399 (is_implicated_in)
Disease	Female sterility	ADIPOR1 ADIPOR2	8.76e-04	28	46	2	C0917730
Disease	Female infertility	ADIPOR1 ADIPOR2	8.76e-04	28	46	2	C0021361
Disease	malate measurement	SLC13A3 TRIP12	1.01e-03	30	46	2	EFO_0010508
Disease	fatty liver disease (biomarker_via_orthology)	ABCC3 ADIPOR2	1.22e-03	33	46	2	DOID:9452 (biomarker_via_orthology)
Disease	differentiated thyroid carcinoma	PCNX2 ADGRG6	1.37e-03	35	46	2	EFO_1002017
Disease	vitamin D deficiency	CALCB BCAS1	1.53e-03	37	46	2	EFO_0003762

Protein segments in the cluster

Peptide	Gene	Start	Entry
CFLHKLPTFLFMKRP	CHRNB4	336	P30926
FAMALKCVKTSRFFP	SLC4A9	641	Q96Q91
TTPTKPFRLQCSMFF	CFAP61	921	Q8NHU2
MGFRKFSPFLALSIL	CALCB	1	P10092
KPSPLLFLFALYIMC	ADGRG6	16	Q86SQ4
MSFPCKFVASFLLIF	CD2	1	P06729
FVSRLPLFSRMKPAS	ATP10D	656	Q9P241
CLRFFSPAIMSPKLF	RASA4	471	O43374
PLMAALPAFFAKSAT	OPN1MW3	301	P0DN78
RPPMPSFRACFKSIF	ADIPOR2	126	Q86V24
CLRFFSPAIMSPKLF	RASA4B	471	C9J798
SMLFFFSKPVGIRPF	ITPR2	2276	Q14571
ILACFREKPPFFSAK	ABCC3	186	O15438
PLMAALPAFFAKSAT	OPN1MW2	301	P0DN77
RFSPSPLSMKQFLDF	PDK1	51	Q15118
PIAFARGIKLSFMPF	DBT	296	P11182
LFLRFLCPAIMSPSL	DAB2IP	521	Q5VWQ8
PPMPSFRACFKSIFR	ADIPOR1	116	Q96A54
PCFASMLTKKLHFFP	CASP6	276	P55212
SVLMSFIQCRLFPKF	PCNX2	1056	A6NKB5
SFLLTPITMSLPFCA	OR2T6	156	Q8NHC8
FMLKRFPYCGSPVLS	OR51G2	166	Q8NGK0
SLFLRFLCPAIMSPS	RASAL2	476	Q9UJF2
PAFSLVFPFLKMVLT	GCN1	976	Q92616
SFKSMLLVLPFPFTL	OR51A2	151	Q8NGJ7
SFKSMLLVLPFPFTL	OR51A4	151	Q8NGJ6
FRMLLASPGACFKLF	PADI3	486	Q9ULW8
PLMAALPAFFAKSAT	OPN1MW	301	P04001
MGPLKAFLFSPFLLR	GABRG1	1	Q8N1C3
PEAPAAKSRFFLMLS	BCAS1	86	O75363
MFAILLFTRDPKFIP	SLC13A3	351	Q8WWT9
SVAFLFSLFLPMPKK	SLC19A3	181	Q9BZV2
KLFRPAAFLPFMAPT	SFXN4	106	Q6P4A7
LSGKFRIPFFMSTEC	SIK3	276	Q9Y2K2
ASALMTAIFPRFSKP	ST3GAL3	91	Q11203
FDLRPISFPACFLQM	OR56A3	91	Q8NH54
SPPLTMLFLCATKFS	POLH	416	Q9Y253
KLCTFSQRFPLPSMY	TBC1D7	41	Q9P0N9
MLCPSKISPFLHLDF	TLR1	341	Q15399
TKFFMLLTFPLSFPI	CNNM4	306	Q6P4Q7
FPLESFHCTSPRKMA	ATG4D	371	Q86TL0
LPLIFLFLCKSDPMA	STK31	791	Q9BXU1
PLMAFPCASYKAFLA	PLA1A	276	Q53H76
MSAPKLLSLGCIFFP	TYRP1	1	P17643
FSFAIKTRMLFLPCS	nan	111	Q6ZUT4
ASLFLRFLCPAIMSP	SYNGAP1	591	Q96PV0
AFPAAVSSMKKFCRP	PSD2	631	Q9BQI7
PARVPFSMKFFLVAI	MT-ND3	46	P03897
MPPFLITLFLFHSCC	SERPINE3	1	A8MV23
MLCPHAPSTFKFLNF	TLR6	346	Q9Y2C9
MFLKFVTSCSRPPLL	UBE3B	971	Q7Z3V4
TPFFMASLLCCGPKL	RNASEK	36	Q6P5S7
PLFLLFIICSFLMSP	SLC6A4	546	P31645
KTCPFFFPFDTRQML	TRIP12	1536	Q14669
TARLAMTLPFFAFPL	LNPK	71	Q9C0E8