Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane-ephrin receptor activity

EPHB2 EPHA6 EPHA7

1.68e-0615323GO:0005005
GeneOntologyMolecularFunctionephrin receptor activity

EPHB2 EPHA6 EPHA7

3.56e-0619323GO:0005003
GeneOntologyMolecularFunctionkinase activity

EPHB2 TNIK EPHA6 MAP4K4 AK8 MINK1 PTK6 EPHA7

2.06e-05764328GO:0016301
GeneOntologyMolecularFunctionprotein kinase activity

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

3.74e-05600327GO:0004672
GeneOntologyMolecularFunctionprotein tyrosine kinase activity

EPHB2 EPHA6 PTK6 EPHA7

8.19e-05145324GO:0004713
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

EPHB2 TNIK EPHA6 MAP4K4 AK8 MINK1 PTK6 EPHA7

8.84e-05938328GO:0016772
GeneOntologyMolecularFunctionphosphotransferase activity, alcohol group as acceptor

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

1.07e-04709327GO:0016773
GeneOntologyMolecularFunctionnuclear receptor activity

NR4A3 NR6A1 STAT3

1.20e-0460323GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

NR4A3 NR6A1 STAT3

1.26e-0461323GO:0098531
GeneOntologyMolecularFunctiontransmembrane receptor protein tyrosine kinase activity

EPHB2 EPHA6 EPHA7

1.53e-0465323GO:0004714
GeneOntologyMolecularFunctionaxon guidance receptor activity

EPHB2 EPHA7

1.92e-0413322GO:0008046
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

EPHB2 EPHA6 EPHA7

3.38e-0485323GO:0019199
GeneOntologyMolecularFunctionnuclear glucocorticoid receptor binding

NR4A3 STAT3

4.64e-0420322GO:0035259
GeneOntologyMolecularFunctionhistone acetyltransferase binding

CITED2 NR4A3

9.83e-0429322GO:0035035
GeneOntologyBiologicalProcessneuron projection morphogenesis

EPHB2 TNIK OR8A1 NR4A3 NYAP2 EPHA6 MAP4K4 MINK1 EPHA7

2.43e-06802329GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EPHB2 TNIK OR8A1 NR4A3 NYAP2 EPHA6 MAP4K4 MINK1 EPHA7

2.89e-06819329GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

EPHB2 TNIK OR8A1 NR4A3 NYAP2 EPHA6 MAP4K4 MINK1 EPHA7

3.10e-06826329GO:0048858
GeneOntologyBiologicalProcessneuron development

EPHB2 TNIK OR8A1 NR4A3 PCARE NYAP2 EPHA6 MAP4K4 MINK1 PTK6 EPHA7

7.06e-0614633211GO:0048666
GeneOntologyBiologicalProcesscell morphogenesis

EPHB2 TNIK OR8A1 NR4A3 NYAP2 EPHA6 MAP4K4 NBEAL2 MINK1 EPHA7

8.13e-0611943210GO:0000902
GeneOntologyBiologicalProcessmicrovillus assembly

TNIK MAP4K4 MINK1

1.08e-0528323GO:0030033
GeneOntologyBiologicalProcessneuron projection development

EPHB2 TNIK OR8A1 NR4A3 NYAP2 EPHA6 MAP4K4 MINK1 PTK6 EPHA7

1.55e-0512853210GO:0031175
GeneOntologyBiologicalProcessmicrovillus organization

TNIK MAP4K4 MINK1

1.96e-0534323GO:0032528
GeneOntologyBiologicalProcessaxon guidance

EPHB2 OR8A1 NR4A3 EPHA6 EPHA7

7.21e-05285325GO:0007411
GeneOntologyBiologicalProcessneuron projection guidance

EPHB2 OR8A1 NR4A3 EPHA6 EPHA7

7.33e-05286325GO:0097485
GeneOntologyBiologicalProcessephrin receptor signaling pathway

EPHB2 EPHA6 EPHA7

7.97e-0554323GO:0048013
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

EPHB2 TNIK OR8A1 NR4A3 EPHA6 MINK1 EPHA7

1.22e-04748327GO:0048667
GeneOntologyBiologicalProcessregulation of growth

CITED2 FOXS1 SH3PXD2B RPTOR STAT3 PTK6 EPHA7

1.55e-04777327GO:0040008
GeneOntologyBiologicalProcesscellular response to leptin stimulus

NR4A3 STAT3

3.92e-0419322GO:0044320
GeneOntologyBiologicalProcessregulation of multicellular organism growth

FOXS1 SH3PXD2B STAT3

4.00e-0493323GO:0040014
GeneOntologyBiologicalProcessprotein autophosphorylation

TNIK MINK1 PTK6 EPHA7

4.10e-04228324GO:0046777
GeneOntologyBiologicalProcessregulation of developmental growth

CITED2 FOXS1 SH3PXD2B STAT3 EPHA7

4.42e-04421325GO:0048638
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

EPHB2 TNIK DNHD1 MAP4K4 MINK1 CFAP65

5.06e-04670326GO:0120031
GeneOntologyBiologicalProcesscell projection assembly

EPHB2 TNIK DNHD1 MAP4K4 MINK1 CFAP65

5.69e-04685326GO:0030031
GeneOntologyBiologicalProcessresponse to leptin

NR4A3 STAT3

5.78e-0423322GO:0044321
GeneOntologyBiologicalProcesspositive regulation of JNK cascade

TNIK MAP4K4 MINK1

6.03e-04107323GO:0046330
GeneOntologyBiologicalProcessretinal ganglion cell axon guidance

EPHB2 EPHA7

6.30e-0424322GO:0031290
GeneOntologyCellularComponentneuron to neuron synapse

EPHB2 TNIK IGSF9B STAT3 MINK1 EPHA7

1.03e-04523316GO:0098984
GeneOntologyCellularComponentdendrite

EPHB2 RIN3 IGSF9B EPHA6 RPTOR MINK1 EPHA7

2.12e-04858317GO:0030425
GeneOntologyCellularComponentdendritic tree

EPHB2 RIN3 IGSF9B EPHA6 RPTOR MINK1 EPHA7

2.15e-04860317GO:0097447
GeneOntologyCellularComponentpostsynaptic density

TNIK IGSF9B STAT3 MINK1 EPHA7

4.89e-04451315GO:0014069
GeneOntologyCellularComponentasymmetric synapse

TNIK IGSF9B STAT3 MINK1 EPHA7

6.30e-04477315GO:0032279
GeneOntologyCellularComponentpostsynaptic specialization

TNIK IGSF9B STAT3 MINK1 EPHA7

8.01e-04503315GO:0099572
GeneOntologyCellularComponentsomatodendritic compartment

EPHB2 RIN3 IGSF9B EPHA6 RPTOR MINK1 EPHA7

1.80e-031228317GO:0036477
GeneOntologyCellularComponentpostsynapse

EPHB2 TNIK IGSF9B STAT3 MINK1 EPHA7

3.40e-031018316GO:0098794
GeneOntologyCellularComponentsperm flagellum

DNHD1 AK8 CFAP65

3.85e-03214313GO:0036126
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

EPHB2 EPHA7

4.43e-0367312GO:0098686
DomainRECEPTOR_TYR_KIN_V_2

EPHB2 EPHA6 EPHA7

1.35e-0614303PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHB2 EPHA6 EPHA7

1.35e-0614303PS00790
DomainEphA2_TM

EPHB2 EPHA6 EPHA7

1.35e-0614303PF14575
DomainTyr_kinase_ephrin_rcpt

EPHB2 EPHA6 EPHA7

1.35e-0614303IPR016257
DomainEph_TM

EPHB2 EPHA6 EPHA7

1.35e-0614303IPR027936
DomainEphrin_rcpt_lig-bd_dom

EPHB2 EPHA6 EPHA7

1.35e-0614303IPR001090
DomainTyr_kinase_rcpt_V_CS

EPHB2 EPHA6 EPHA7

1.35e-0614303IPR001426
DomainEPH_LBD

EPHB2 EPHA6 EPHA7

1.35e-0614303PS51550
DomainEPH_lbd

EPHB2 EPHA6 EPHA7

1.35e-0614303SM00615
DomainCNH

TNIK MAP4K4 MINK1

1.35e-0614303SM00036
DomainEphrin_lbd

EPHB2 EPHA6 EPHA7

1.35e-0614303PF01404
DomainCNH

TNIK MAP4K4 MINK1

1.68e-0615303PS50219
DomainCNH_dom

TNIK MAP4K4 MINK1

1.68e-0615303IPR001180
DomainCNH

TNIK MAP4K4 MINK1

1.68e-0615303PF00780
DomainProtein_kinase_ATP_BS

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

1.82e-06379307IPR017441
DomainPROTEIN_KINASE_ATP

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

6.45e-06459307PS00107
DomainEphrin_rec_like

EPHB2 EPHA6 EPHA7

8.40e-0625303SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

EPHB2 EPHA6 EPHA7

8.40e-0625303IPR011641
DomainProt_kinase_dom

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

9.75e-06489307IPR000719
DomainPROTEIN_KINASE_DOM

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

1.03e-05493307PS50011
DomainTyrKc

EPHB2 EPHA6 PTK6 EPHA7

1.15e-0588304SM00219
DomainTyr_kinase_cat_dom

EPHB2 EPHA6 PTK6 EPHA7

1.15e-0588304IPR020635
DomainPROTEIN_KINASE_TYR

EPHB2 EPHA6 PTK6 EPHA7

1.69e-0597304PS00109
DomainTyr_kinase_AS

EPHB2 EPHA6 PTK6 EPHA7

1.69e-0597304IPR008266
DomainKinase-like_dom

EPHB2 TNIK EPHA6 MAP4K4 MINK1 PTK6 EPHA7

1.90e-05542307IPR011009
DomainPkinase_Tyr

EPHB2 EPHA6 PTK6 EPHA7

5.18e-05129304PF07714
DomainSer-Thr/Tyr_kinase_cat_dom

EPHB2 EPHA6 PTK6 EPHA7

6.74e-05138304IPR001245
Domainfn3

EPHB2 IGSF9B EPHA6 EPHA7

1.25e-04162304PF00041
DomainEphrin_rec_like

EPHB2 EPHA7

1.36e-0411302PF07699
DomainSAM_1

EPHB2 EPHA6 EPHA7

1.75e-0468303PF00536
DomainFN3

EPHB2 IGSF9B EPHA6 EPHA7

2.09e-04185304SM00060
Domain-

EPHB2 EPHA6 EPHA7

2.16e-04733032.60.120.260
DomainFN3

EPHB2 IGSF9B EPHA6 EPHA7

2.76e-04199304PS50853
DomainFN3_dom

EPHB2 IGSF9B EPHA6 EPHA7

3.32e-04209304IPR003961
DomainSAM

EPHB2 EPHA6 EPHA7

3.74e-0488303SM00454
DomainGalactose-bd-like

EPHB2 EPHA6 EPHA7

4.54e-0494303IPR008979
DomainSAM_DOMAIN

EPHB2 EPHA6 EPHA7

4.69e-0495303PS50105
DomainSAM

EPHB2 EPHA6 EPHA7

4.98e-0497303IPR001660
Domain-

EPHB2 EPHA6 EPHA7

6.45e-041063031.10.150.50
DomainSH2

RIN3 STAT3 PTK6

7.19e-04110303SM00252
DomainSH2

RIN3 STAT3 PTK6

7.38e-04111303PS50001
DomainSH2

RIN3 STAT3 PTK6

7.57e-04112303IPR000980
Domain-

RIN3 STAT3 PTK6

7.57e-041123033.30.505.10
DomainSAM/pointed

EPHB2 EPHA6 EPHA7

8.60e-04117303IPR013761
DomainGrowth_fac_rcpt_

EPHB2 EPHA6 EPHA7

1.97e-03156303IPR009030
Domainzf-C4

NR4A3 NR6A1

2.47e-0346302PF00105
DomainNUCLEAR_REC_DBD_1

NR4A3 NR6A1

2.47e-0346302PS00031
DomainZnf_hrmn_rcpt

NR4A3 NR6A1

2.47e-0346302IPR001628
DomainNuclear_hrmn_rcpt

NR4A3 NR6A1

2.47e-0346302IPR001723
DomainZnF_C4

NR4A3 NR6A1

2.47e-0346302SM00399
DomainNUCLEAR_REC_DBD_2

NR4A3 NR6A1

2.47e-0346302PS51030
Domain-

NR4A3 NR6A1

2.58e-03473021.10.565.10
DomainHOLI

NR4A3 NR6A1

2.69e-0348302SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR4A3 NR6A1

2.69e-0348302IPR000536
DomainHormone_recep

NR4A3 NR6A1

2.69e-0348302PF00104
Domain-

NR4A3 NR6A1

3.77e-03573023.30.50.10
DomainZnf_NHR/GATA

NR4A3 NR6A1

3.90e-0358302IPR013088
DomainSH3_2

SH3PXD2B PTK6

8.38e-0386302IPR011511
DomainSH3_2

SH3PXD2B PTK6

8.38e-0386302PF07653
PathwayWP_HIPPOYAP_SIGNALING

TNIK MAP4K4 MINK1

4.31e-0622213M39821
PathwayREACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS

EPHB2 EPHA6 EPHA7

1.66e-0534213MM15025
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

TNIK MAP4K4 MINK1

2.14e-0537213MM14899
PathwayREACTOME_EPH_EPHRIN_MEDIATED_REPULSION_OF_CELLS

EPHB2 EPHA6 EPHA7

5.67e-0551213M27311
PathwayREACTOME_EPH_EPHRIN_SIGNALING

EPHB2 EPHA6 EPHA7

1.17e-0465213MM14911
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

CITED2 TNIK MAP4K4 RPTOR STAT3 MINK1 PTK6

1.32e-04828217M27827
PathwayREACTOME_POU5F1_OCT4_SOX2_NANOG_ACTIVATE_GENES_RELATED_TO_PROLIFERATION

NR6A1 STAT3

1.63e-0413212M27209
PathwayREACTOME_CELLULAR_SENESCENCE

TNIK MAP4K4 STAT3 MINK1

1.84e-04197214M27188
PathwayREACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE

EPHA6 EPHA7

3.19e-0418212MM15023
PathwayREACTOME_EPH_EPHRIN_SIGNALING

EPHB2 EPHA6 EPHA7

3.29e-0492213M27201
PathwayREACTOME_CELLULAR_SENESCENCE

TNIK MAP4K4 MINK1

6.98e-04119213MM14901
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

CITED2 TNIK MAP4K4 RPTOR MINK1

7.31e-04505215MM15548
PathwayREACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE

TNIK MAP4K4 MINK1

8.05e-04125213M27186
PathwayREACTOME_EPHA_MEDIATED_GROWTH_CONE_COLLAPSE

EPHA6 EPHA7

8.38e-0429212M27309
PathwayKEGG_AXON_GUIDANCE

EPHB2 EPHA6 EPHA7

8.83e-04129213M5539
PathwayWP_ANGIOPOIETINLIKE_PROTEIN_8_REGULATORY_PATHWAY

MAP4K4 RPTOR MINK1

9.43e-04132213M39338
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_PLURIPOTENT_STEM_CELLS

NR6A1 STAT3

9.58e-0431212M27393
PathwayWP_JAKSTAT_SIGNALING_IN_THE_REGULATION_OF_BETA_CELLS

RPTOR STAT3

1.15e-0334212M48081
PathwayPID_EPHA_FWDPATHWAY

EPHA6 EPHA7

1.15e-0334212M177
PathwayWP_NEURAL_CREST_CELL_MIGRATION_DURING_DEVELOPMENT

EPHB2 STAT3

1.59e-0340212M39798
PathwayWP_CATABOLISM_OF_SKELETAL_MUSCLE_IN_CACHEXIA

RPTOR STAT3

1.59e-0340212M48337
PathwayPID_EPHB_FWD_PATHWAY

EPHB2 MAP4K4

1.59e-0340212M62
PathwayWP_NEURAL_CREST_CELL_MIGRATION_IN_CANCER

EPHB2 STAT3

1.84e-0343212M39788
PathwayPID_TNF_PATHWAY

TNIK MAP4K4

2.10e-0346212M128
PathwayWP_MICROTUBULE_CYTOSKELETON_REGULATION

EPHB2 STAT3

2.29e-0348212M39566
PathwayREACTOME_SIGNALING_BY_PTK6

STAT3 PTK6

2.29e-0348212MM15479
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR4A3 NR6A1

2.29e-0348212MM14987
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR4A3 NR6A1

2.78e-0353212M8276
PathwayWP_INTERFERON_TYPE_I_SIGNALING

RPTOR STAT3

2.89e-0354212M39435
PathwayREACTOME_SIGNALING_BY_PTK6

STAT3 PTK6

2.89e-0354212M29742
Pubmed

HOXA13 directly regulates EphA6 and EphA7 expression in the genital tubercle vascular endothelia.

EPHB2 EPHA6 EPHA7

8.45e-081032317304517
Pubmed

Competition is a driving force in topographic mapping.

EPHB2 EPHA6 EPHA7

1.16e-071132322065784
Pubmed

Rap2A links intestinal cell polarity to brush border formation.

TNIK MAP4K4 MINK1

3.19e-071532322797597
Pubmed

Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis.

EPHB2 EPHA6 EPHA7

3.93e-07163238755474
Pubmed

Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.

EPHB2 EPHA6 EPHA7

4.77e-071732312217323
Pubmed

Expression of Ephs and ephrins in developing mouse inner ear.

EPHB2 EPHA6 EPHA7

6.79e-071932312684176
Pubmed

STAT3-EphA7 axis contributes to the progression of esophageal squamous cell carcinoma.

STAT3 EPHA7

8.20e-07232237738252
Pubmed

Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane.

STAT3 PTK6

8.20e-07232221741923
Pubmed

Knockdown of long noncoding RNA AC245100.4 inhibits the tumorigenesis of prostate cancer cells via the STAT3/NR4A3 axis.

NR4A3 STAT3

8.20e-07232234657447
Pubmed

Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.

EPHB2 EPHA6 EPHA7

9.30e-07213239267020
Pubmed

Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.

EPHB2 EPHA6 EPHA7

9.30e-072132310495276
Pubmed

Developmental expression of Eph and ephrin family genes in mammalian small intestine.

EPHB2 EPHA6 EPHA7

9.30e-072132320112066
Pubmed

Roles of Eph receptors and ephrins in segmental patterning.

EPHB2 EPHA6 EPHA7

9.30e-072132311128993
Pubmed

Eph receptors and ephrins: regulators of guidance and assembly.

EPHB2 EPHA6 EPHA7

9.30e-072132310730216
Pubmed

The protein tyrosine kinase family of the human genome.

EPHB2 EPHA6 PTK6 EPHA7

1.03e-068332411114734
Pubmed

Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.

EPHB2 EPHA6 EPHA7

1.24e-062332319542359
Pubmed

Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions.

EPHB2 EPHA6 EPHA7

1.24e-062332325480914
Pubmed

Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.

EPHB2 EPHA6 EPHA7

1.41e-062432316446123
Pubmed

Interactions of STAP-2 with Brk and STAT3 participate in cell growth of human breast cancer cells.

STAT3 PTK6

2.46e-06332220929863
Pubmed

STAP-2 is phosphorylated at tyrosine-250 by Brk and modulates Brk-mediated STAT3 activation.

STAT3 PTK6

2.46e-06332219393627
Pubmed

Identification of STAT3 as a specific substrate of breast tumor kinase.

STAT3 PTK6

2.46e-06332216568091
Pubmed

Suppressor of cytokine signaling 3 inhibits breast tumor kinase activation of STAT3.

STAT3 PTK6

2.46e-06332222547065
Pubmed

MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.

TNIK MINK1

2.46e-06332218930710
Pubmed

Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation.

EPHB2 EPHA6 EPHA7

3.79e-063332326830346
Pubmed

cDNA cloning and tissue distribution of five human EPH-like receptor protein-tyrosine kinases.

EPHB2 EPHA7

4.92e-0643227898931
Pubmed

Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature.

EPHB2 EPHA6 EPHA7

7.93e-064232311439183
Pubmed

Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk.

EPHB2 EPHA7

8.19e-06532210932185
Pubmed

Differential Roles of the mTOR-STAT3 Signaling in Dermal γδ T Cell Effector Function in Skin Inflammation.

RPTOR STAT3

8.19e-06532231167146
Pubmed

Rapamycin-Resistant mTOR Activity Is Required for Sensory Axon Regeneration Induced by a Conditioning Lesion.

RPTOR STAT3

8.19e-06532228101526
Pubmed

Disruption of mammalian target of rapamycin complex 1 in macrophages decreases chemokine gene expression and atherosclerosis.

RPTOR STAT3

1.23e-05632224687132
Pubmed

Opposing gradients of ephrin-As and EphA7 in the superior colliculus are essential for topographic mapping in the mammalian visual system.

EPHA6 EPHA7

1.23e-05632215996548
Pubmed

Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse.

EPHB2 EPHA6 EPHA7

1.43e-055132319769959
Pubmed

PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands.

EPHB2 EPHA7

1.72e-0573229883737
Pubmed

Mistargeting hippocampal axons by expression of a truncated Eph receptor.

EPHA6 EPHA7

2.29e-05832212124402
Pubmed

Genetic analysis of ephrin-A2 and ephrin-A5 shows their requirement in multiple aspects of retinocollicular mapping.

EPHA6 EPHA7

2.29e-05832210774725
Pubmed

Degenerate PCR-based cloning method for Eph receptors and analysis of their expression in the developing murine central nervous system and vasculature.

EPHB2 EPHA7

2.94e-05932211403717
Pubmed

PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.

EPHB2 EPHA7

2.94e-0593229707552
Pubmed

Embryonic expression of EphA receptor genes in mice supports their candidacy for involvement in cleft lip and palate.

EPHA6 EPHA7

3.67e-051032225073978
Pubmed

Quantitative assessment of computational models for retinotopic map formation.

EPHA6 EPHA7

3.67e-051032225367067
Pubmed

EphrinA5 Signaling Is Required for the Distinctive Targeting of Raphe Serotonin Neurons in the Forebrain.

EPHA6 EPHA7

3.67e-051032228197551
Pubmed

Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space.

EPHB2 NR4A3

3.67e-051032220652952
Pubmed

EphA receptors inhibit anti-CD3-induced apoptosis in thymocytes.

EPHA6 EPHA7

3.67e-051032216547242
Pubmed

Selective inhibition of spinal cord neurite outgrowth and cell survival by the Eph family ligand ephrin-A5.

EPHA6 EPHA7

4.49e-051132210559410
Pubmed

Time-resolved mass spectrometry of tyrosine phosphorylation sites in the epidermal growth factor receptor signaling network reveals dynamic modules.

EPHB2 STAT3 PTK6

4.57e-057532315951569
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TNIK SH3PXD2B NYAP2 MAP4K4

4.71e-0521832433378226
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

EPHB2 TNIK MAP4K4

5.14e-057832317192257
Pubmed

Ephrin/ephrin receptor expression during early stages of mouse inner ear development.

EPHB2 EPHA7

5.38e-051232221465626
Pubmed

The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.

MAP4K4 MINK1

5.38e-051232235027733
Pubmed

Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling.

EPHB2 STAT3

6.36e-051332220513444
Pubmed

Eph-ephrin A system regulates murine blastocyst attachment and spreading.

EPHA6 EPHA7

6.36e-051332217039519
Pubmed

EphA family gene expression in the developing mouse neocortex: regional patterns reveal intrinsic programs and extrinsic influence.

EPHA6 EPHA7

6.36e-051332212528186
Pubmed

Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue.

EPHA6 EPHA7

7.41e-051432226941654
Pubmed

A role for the EphA family in the topographic targeting of vomeronasal axons.

EPHA6 EPHA7

7.41e-051432211222144
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

EPHB2 IGSF9B EPHA6

8.13e-059132328558017
Pubmed

PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.

EPHB2 EPHA7

9.76e-051632238429579
Pubmed

Cited2 Regulates Neocortical Layer II/III Generation and Somatosensory Callosal Projection Neuron Development and Connectivity.

CITED2 EPHA7

1.24e-041832227307230
Pubmed

Tracheal separation is driven by NKX2-1-mediated repression of Efnb2 and regulation of endodermal cell sorting.

EPHB2 EPHA7

1.39e-041932235294885
Pubmed

Multiple roles of EPH receptors and ephrins in neural development.

EPHB2 EPHA7

1.54e-042032211256076
Pubmed

The ephrins and Eph receptors in neural development.

EPHB2 EPHA7

1.54e-04203229530499
Pubmed

Eph receptors and ephrins: effectors of morphogenesis.

EPHB2 EPHA7

1.54e-042032210207129
Pubmed

Epidermal inactivation of the glucocorticoid receptor triggers skin barrier defects and cutaneous inflammation.

EPHB2 STAT3

1.54e-042032222951731
Pubmed

The Eph family receptors and ligands.

EPHB2 EPHA7

1.54e-04203229576626
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

EPHB2 IGSF9B MAP4K4 MINK1 PTK6 EPHA7

1.60e-0491032636736316
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

TNIK MAP4K4 NBEAL2 MINK1 EPHA7

1.61e-0456932530639242
Pubmed

Inactivation of mTORC1 in the developing brain causes microcephaly and affects gliogenesis.

RPTOR STAT3

1.70e-042132223637172
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

EPHB2 EPHA6 EPHA7

1.71e-0411732317145500
Pubmed

Twist is required for patterning the cranial nerves and maintaining the viability of mesodermal cells.

EPHB2 CITED2

1.87e-042232215162501
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

EPHB2 EPHA6

2.05e-042332224360543
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TNIK SH3PXD2B NYAP2 MAP4K4 RPTOR MINK1

2.17e-0496332628671696
Pubmed

LZTR1 is a regulator of RAS ubiquitination and signaling.

TNIK MAP4K4 MINK1

2.18e-0412732330442766
Pubmed

FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells.

RPTOR STAT3

2.43e-042532228069738
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

TINAGL1 DNHD1 C11orf24 IGSF9B EPHA6 NBEAL2

2.45e-0498532612975309
Pubmed

Sustained activation of mTOR pathway in embryonic neural stem cells leads to development of tuberous sclerosis complex-associated lesions.

RPTOR STAT3

3.51e-043032222056141
Pubmed

The transcription factor gene Nfib is essential for both lung maturation and brain development.

EPHB2 NFIC

3.51e-043032215632069
Pubmed

Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.

MAP4K4 NFIC MINK1 PTK6

3.65e-0437232422939624
Pubmed

Yap and Taz are required for Ret-dependent urinary tract morphogenesis.

EPHB2 EPHA7

3.75e-043132226243870
Pubmed

Genome-wide association scan for survival on dialysis in African-Americans with type 2 diabetes.

RIN3 EPHA7

4.00e-043232221546767
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PRICKLE3 MAP4K4 NFIC RPTOR MINK1

6.59e-0477432515302935
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

EPHB2 CITED2 NR4A3 PRICKLE3 RPTOR STAT3

7.08e-04120332629180619
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

CITED2 ZNF438 NR6A1 PRICKLE3 STAT3

8.00e-0480832520412781
Pubmed

mTORC1 accelerates retinal development via the immunoproteasome.

RPTOR STAT3

8.28e-044632229950673
Pubmed

Identification of NPM-ALK interacting proteins by tandem mass spectrometry.

EPHB2 STAT3

8.64e-044732214968112
InteractionSLC9A8 interactions

MAP4K4 MINK1 EPHA7

6.70e-0625303int:SLC9A8
InteractionEPHB2 interactions

EPHB2 TNIK EPHA6 MAP4K4 EPHA7

1.55e-05216305int:EPHB2
InteractionNCKAP1 interactions

EPHB2 TNIK RIN3 NYAP2 EPHA7

1.62e-05218305int:NCKAP1
InteractionNCK1 interactions

EPHB2 TNIK SH3PXD2B MAP4K4 MINK1

2.78e-05244305int:NCK1
InteractionMAP4K4 interactions

EPHB2 TNIK MAP4K4 MINK1 EPHA7

3.37e-05254305int:MAP4K4
InteractionEPHA7 interactions

EPHB2 TNIK MAP4K4 MINK1 EPHA7

5.54e-05282305int:EPHA7
InteractionEPHA5 interactions

TNIK MAP4K4 STAT3 MINK1

5.93e-05144304int:EPHA5
InteractionKCNE3 interactions

TNIK PRICKLE3 MAP4K4 MINK1 EPHA7

6.97e-05296305int:KCNE3
InteractionEPHA2 interactions

EPHB2 TNIK EPHA6 MAP4K4 NFIC MINK1 EPHA7

7.10e-05719307int:EPHA2
InteractionFOS interactions

EPHB2 NR4A3 NR6A1 NFIC STAT3

8.93e-05312305int:FOS
InteractionSH3KBP1 interactions

EPHB2 TNIK SH3PXD2B RIN3 STAT3

9.34e-05315305int:SH3KBP1
InteractionCYFIP2 interactions

EPHB2 TNIK RIN3 NYAP2 EPHA7

1.05e-04323305int:CYFIP2
InteractionAFDN interactions

EPHB2 PRICKLE3 MAP4K4 MINK1 EPHA7

1.21e-04333305int:AFDN
InteractionEFNA5 interactions

EPHB2 EPHA6 EPHA7

1.40e-0468303int:EFNA5
InteractionNLK interactions

RPTOR FAM222B STAT3

1.52e-0470303int:NLK
InteractionCTTNBP2NL interactions

TNIK MAP4K4 MINK1

1.66e-0472303int:CTTNBP2NL
InteractionMINK1 interactions

TNIK MAP4K4 MINK1 EPHA7

1.84e-04193304int:MINK1
InteractionCSF1R interactions

EPHB2 STAT3 EPHA7

1.87e-0475303int:CSF1R
InteractionTSC1 interactions

TNIK RIN3 RPTOR FAM222B MINK1

1.88e-04366305int:TSC1
InteractionNTRK3 interactions

TNIK MAP4K4 RPTOR MINK1 EPHA7

2.08e-04374305int:NTRK3
InteractionTNIK interactions

EPHB2 TNIK MAP4K4 MINK1 EPHA7

2.27e-04381305int:TNIK
InteractionFGFR1 interactions

TNIK SH3PXD2B MAP4K4 STAT3 MINK1 PTK6

2.90e-04632306int:FGFR1
InteractionABI1 interactions

EPHB2 TNIK RIN3 MINK1

3.19e-04223304int:ABI1
InteractionGALNT13 interactions

TNIK MINK1

3.23e-0418302int:GALNT13
InteractionRAP2A interactions

TNIK MAP4K4 MINK1

3.31e-0491303int:RAP2A
InteractionFGFR1OP2 interactions

TNIK MAP4K4 MINK1

3.64e-0494303int:FGFR1OP2
InteractionSTRIP1 interactions

TNIK MAP4K4 MINK1

3.99e-0497303int:STRIP1
InteractionEFNA1 interactions

EPHB2 EPHA6 EPHA7

4.76e-04103303int:EFNA1
InteractionFGFR4 interactions

TNIK SH3PXD2B MAP4K4 STAT3 EPHA7

5.29e-04458305int:FGFR4
InteractionSEC23A interactions

EPHB2 TNIK EPHA6 EPHA7

5.30e-04255304int:SEC23A
InteractionHNRNPCL3 interactions

MAP4K4 MINK1

5.32e-0423302int:HNRNPCL3
InteractionABL2 interactions

EPHB2 STAT3 EPHA7

5.32e-04107303int:ABL2
InteractionLCK interactions

RIN3 MAP4K4 STAT3 MINK1 PTK6

5.55e-04463305int:LCK
InteractionNR6A1 interactions

NR4A3 NR6A1

5.79e-0424302int:NR6A1
InteractionLYN interactions

TNIK IGSF9B MAP4K4 STAT3 MINK1 EPHA7

5.80e-04720306int:LYN
InteractionNCK2 interactions

TNIK SH3PXD2B MAP4K4 MINK1

5.86e-04262304int:NCK2
InteractionEPHA3 interactions

EPHB2 STAT3 EPHA7

5.92e-04111303int:EPHA3
InteractionWASF1 interactions

EPHB2 TNIK NYAP2

6.74e-04116303int:WASF1
InteractionNANOS2 interactions

MAP4K4 MINK1

6.81e-0426302int:NANOS2
InteractionFANCD2OS interactions

MAP4K4 MINK1

6.81e-0426302int:FANCD2OS
InteractionCAMKV interactions

TINAGL1 TNIK PRICKLE3

7.08e-04118303int:CAMKV
InteractionTUBA1B interactions

EPHB2 RIN3 RPTOR MINK1 PTK6

7.72e-04498305int:TUBA1B
InteractionOCLN interactions

EPHB2 TNIK MAP4K4 MINK1 EPHA7

7.86e-04500305int:OCLN
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHB2 EPHA6 EPHA7

3.56e-07141931095
GeneFamilyFibronectin type III domain containing

EPHB2 IGSF9B EPHA6 EPHA7

2.06e-05160194555
GeneFamilySterile alpha motif domain containing

EPHB2 EPHA6 EPHA7

1.02e-0488193760
GeneFamilyNuclear hormone receptors

NR4A3 NR6A1

1.19e-034919271
GeneFamilySH2 domain containing

STAT3 PTK6

4.97e-03101192741
GeneFamilyWD repeat domain containing

RPTOR NBEAL2

3.04e-02262192362
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_k-means-cluster#5_top-relative-expression-ranked_1000

CITED2 FOXS1 RIN3 NFIC STAT3

1.15e-05214305gudmap_developingGonad_e16.5_testes_1000_k5
CoexpressionAtlasDevelopingGonad_e18.5_testes_emap-11164_k-means-cluster#4_top-relative-expression-ranked_1000

CITED2 FOXS1 RIN3 NFIC STAT3

5.19e-05293305gudmap_developingGonad_e18.5_testes_1000_k4
CoexpressionAtlasDevelopingGonad_P2_testes_emap-30171_k-means-cluster#4_top-relative-expression-ranked_1000

CITED2 FOXS1 RIN3 NFIC STAT3

7.76e-05319305gudmap_developingGonad_P2_testes_1000_k4
CoexpressionAtlasDevelopingGonad_e16.5_testes_emap-8444_top-relative-expression-ranked_1000

TINAGL1 CITED2 FOXS1 RIN3 NFIC FAM222B STAT3

1.16e-04819307gudmap_developingGonad_e16.5_testes_1000
ToppCellLV-14._Fibroblast_III|World / Chamber and Cluster_Paper

EPHB2 NR4A3 SH3PXD2B STAT3

9.89e-061893243922135d1f6fc768d71ba3b465585fead6ea68a8
ToppCellLV-14._Fibroblast_III|LV / Chamber and Cluster_Paper

EPHB2 NR4A3 SH3PXD2B STAT3

1.10e-05194324927c26aea0147f7a4b8fb3f192de4de263f1b978
ToppCellTCGA-Ovary-Primary_Tumor|TCGA-Ovary / Sample_Type by Project: Shred V9

EPHB2 CITED2 FAM222B

6.00e-0510632314f548be39cec604fbdae0382cbf434fa4049840
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

EPHB2 CITED2 FAM222B

6.00e-05106323939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

EPHB2 CITED2 FAM222B

6.00e-05106323e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

SCART1 NYAP2 NBEAL2

6.17e-051073235277cd6b854307444646c10277abb2c818c48b56
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TINAGL1 FOXS1 PTK6

8.67e-05120323a320799ab5f2ce872e038b15841a23174c5436e8
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AGXT2 IGSF9B PTK6

1.99e-04159323709b57f992a29878cc899d760d144d36cb5cb280
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NR4A3 NR6A1 AK8

2.14e-04163323f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_naive-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF438 NBEAL2 MINK1

2.14e-041633234be3158f2a0ab460cfea8080a7370922910b5da9
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AGXT2 PRICKLE3 FREM1

2.26e-041663239fa8510adfa3050ee182b4b71e5655abb9bb8a76
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TINAGL1 NR4A3 RPTOR

2.30e-04167323774f3264318b002d0df5d06d41d645366038d0bf
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF9B FREM1 EPHA7

2.34e-04168323ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCell343B-Myeloid-Dendritic-cDC_activated|343B / Donor, Lineage, Cell class and subclass (all cells)

NR4A3 NR6A1 MINK1

2.38e-041693232098f15a388d019ed7f1d4c209affd5ca2886dcc
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CITED2 NR4A3 SCART1

2.47e-041713236ab7f103cbdbd49ef687cbb8a42ddc5517af0f7f
ToppCellCOVID-19_Convalescent|World / Disease Group and Platelet Clusters

CITED2 ZNF438 STAT3

2.64e-04175323e9b1faa4c85537f30306619a2f3ada6c8ef0ac6c
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CITED2 NR4A3 RIN3

2.82e-041793233d3716078afdb9a89ddfadb3197cd1b52fa770be
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CITED2 TNIK STAT3

2.87e-04180323f3d35b2ea78afef37a84232adf5e6e26712b618d
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR6A1 PRICKLE3 NBEAL2

2.91e-04181323f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 EPHA7

2.91e-041813239542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 EPHA7

2.91e-041813238f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_VWA2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHB2 EPHA6 FREM1

2.96e-0418232372e65a23cd36085bc880087d3cae92395de918a1
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

NYAP2 NR6A1 NBEAL2

3.01e-04183323942530449e9c6583705eeb8f6f12621daea57252
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

NYAP2 NR6A1 NBEAL2

3.01e-041833237b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 CITED2 FOXS1

3.06e-0418432331dbe6119a3bcd266ae5e9b340c853d9ff680dce
ToppCellfacs-Heart-RV-3m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TINAGL1 CITED2 FOXS1

3.06e-041843239c20b50f8d6ac689d41d5440c835f9db8d04758b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AK8 FREM1 CFAP65

3.06e-04184323d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AK8 FREM1 CFAP65

3.06e-0418432322010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AK8 FREM1 CFAP65

3.06e-04184323264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 EPHA6 FREM1

3.16e-04186323310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CITED2 TNIK IGSF9B

3.16e-04186323c793a3d5709ad504c12fc3b2337746d90236d3ca
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NR4A3 RIN3 NBEAL2

3.16e-04186323305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NR6A1 EPHA7

3.16e-04186323b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FOXS1 NR4A3

3.21e-041873236820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

TNIK AGXT2 EPHA7

3.21e-04187323acd305475f3609800af0d7bc68d83ef41228080b
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SH3PXD2B NYAP2 MAP4K4

3.26e-04188323762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

SH3PXD2B EPHA6 FREM1

3.26e-04188323706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellCOPD-Stromal-SMC|Stromal / Disease state, Lineage and Cell class

TINAGL1 FOXS1 IGSF9B

3.26e-041883239ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 EPHA7

3.31e-0418932313fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 EPHA7

3.31e-04189323204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK EPHA6 EPHA7

3.31e-0418932328b502611829e4a24caff2562545c7db97686099
ToppCellCOVID-19-kidney-PCT-S2|kidney / Disease (COVID-19 only), tissue and cell type

TNIK AGXT2 EPHA7

3.31e-041893230be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 EPHA7

3.36e-04190323989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NBEAL2 FREM1

3.41e-041913233e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 NR6A1

3.41e-041913233c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK AGXT2 NR6A1

3.41e-041913231c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CITED2 NR4A3 RIN3

3.41e-0419132379e7089022063c5f2b2f1b27658c62b741f3a037
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 EPHA6 FREM1

3.41e-04191323fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NYAP2 EPHA6 FREM1

3.41e-041913237b386512284dfaa0e95358b28ee82632ee965e64
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FOXS1 NR4A3

3.46e-0419232371863f18a82394ed9f8e5ec8a4017215382a8284
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TINAGL1 NYAP2 PTK6

3.46e-041923230b954a4e5857dac45d97c491af9b27cb2d1bd339
ToppCellMatrixFB-Fibroblast-D_(Pericyte)|MatrixFB / shred on cell class and cell subclass (v4)

TINAGL1 FOXS1 MINK1

3.46e-04192323630444302511f511ec6976bc045a3b4b9d8d4547
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NR4A3 FREM1 STAT3

3.46e-041923236bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCellLA-14._Fibroblast_III|LA / Chamber and Cluster_Paper

NR4A3 SH3PXD2B STAT3

3.52e-041933237426c291bac59e539c427bcaae18abc7d397d44e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FOXS1 MAP4K4

3.52e-04193323a9349ed5f3c34dcf817b3e84737e5946922ddff3
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TINAGL1 IGSF9B EPHA6

3.57e-04194323efd5efed060edb7f24d59600981bb60ec28ac2ef
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NBEAL2 FREM1

3.57e-0419432369bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TNIK NBEAL2 FREM1

3.57e-0419432304bfc555743f7d8821439d05ae442d15e9886c59
ToppCell10x5'v1-week_12-13-Hematopoietic-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CITED2 TNIK FREM1

3.57e-04194323245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FOXS1 NR4A3

3.57e-041943233b9ada901dfe7a5cc4861a883d3268c53b11e5b6
ToppCellmedial-2-Hematologic-Myeloid_Dendritic_Type_2|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPHB2 NR4A3 RIN3

3.62e-0419532354a404ee1b97d0659fcffafb20d11f878ed453d4
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_2-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPHB2 NR4A3 RIN3

3.62e-0419532335a5302b8b3e76bc92dc38979400c979f0e86550
ToppCell10x5'v1-week_12-13-Hematopoietic-MK-early_MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CITED2 TNIK FREM1

3.62e-04195323fa5fc6f605deb5cae96eec14ba4000b19f877ba6
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CITED2 TNIK STAT3

3.62e-04195323e4caa01d2040a6f4dd90e68c2e1e99c5405e2eba
ToppCellmedial-Hematologic-Myeloid_Dendritic_Type_2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EPHB2 NR4A3 RIN3

3.62e-04195323c0d1ecb378bb482a8e08d7065fcca07a65687dac
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4|TCGA-Prostate / Sample_Type by Project: Shred V9

TINAGL1 SH3PXD2B RIN3

3.62e-041953235562665dd3beb70e2358aa32611a337bef5731c1
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CITED2 TNIK FREM1

3.62e-04195323f1f48e2e57b2282572959b152aad4bee05143f03
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NR4A3 SH3PXD2B RIN3

3.62e-0419532362dc745e1aa3e2e58afa16c7bb2cf9b03d4e8105
ToppCell10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNIK NR4A3 RIN3

3.68e-041963235bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CITED2 MAP4K4 STAT3

3.68e-0419632397ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TINAGL1 FOXS1 NR4A3

3.68e-04196323624f700daea48d9bad4cc554f4776bd809ae1e54
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

DNHD1 NR6A1 PRICKLE3

3.73e-0419732315b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NR4A3 SH3PXD2B RIN3

3.73e-041973231eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

DNHD1 NR6A1 PRICKLE3

3.73e-04197323a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-CD4-positive_helper_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CITED2 TNIK STAT3

3.79e-04198323c4d8d133e571ad3a7c5de93aa7befb67cb7a003d
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-early_MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CITED2 TNIK FREM1

3.79e-04198323fcf53d6ac2e442400fa0c07c6de72e00a9143ba2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TINAGL1 FOXS1 IGSF9B

3.79e-041983237dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK OR8A1 RIN3

3.79e-04198323cc5ca64749e2f4f1d373d9472824df85741702b7
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4|lymph-node_spleen / Manually curated celltypes from each tissue

CITED2 TNIK STAT3

3.79e-041983232cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCellTracheal-NucSeq-Immune_Myeloid-Mast_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK OR8A1 RIN3

3.79e-04198323d4d66f19df078bfc3a83d4664aaf9c7789bde1a5
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 NBEAL2 FREM1

3.85e-04199323f544229f471b4717166dd4b588399afe45cc31b5
ToppCellmLN-T_cell|mLN / Region, Cell class and subclass

CITED2 TNIK STAT3

3.85e-04199323caa37ec509b54e842564d754f100ab1b2a77a7c1
ToppCellmLN-(1)_T_cell|mLN / shred on region, Cell_type, and subtype

CITED2 TNIK STAT3

3.85e-041993234bf2641409c543c2167bff71efa95b00dd7bfe19
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 NBEAL2 FREM1

3.90e-04200323fc77a0c53201c60933d188ea8d4d86bac6325422
ToppCellTracheal-10x5prime-Immune_Myeloid-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK OR8A1 RIN3

3.90e-04200323c3511607692e05f44538a376253673dd18f77908
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)|Neuronal / cells hierarchy compared to all cells using T-Statistic

NYAP2 EPHA6 FREM1

3.90e-04200323d0167f96314be78b6d867bbcc6e4396071d931b8
ToppCell5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB2 NBEAL2 FREM1

3.90e-04200323742441800a2d167c19cee4816ff77424ae6675c6
ToppCellTracheal-10x5prime-Immune_Myeloid-Mast_cell-Mast_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TNIK OR8A1 RIN3

3.90e-042003231c58860932ed47263a5a537a64f0343201463c21
Drugtroglitazone; Up 200; 10uM; PC3; HG-U133A

TINAGL1 CITED2 NR4A3 NBEAL2 FAM222B STAT3

2.25e-07195316431_UP
DrugDoxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A

CITED2 TNIK PRICKLE3 FAM222B MINK1

6.21e-061953154235_DN
DrugTribenoside [10310-32-4]; Up 200; 8.4uM; PC3; HT_HG-U133A

CITED2 RIN3 NBEAL2 MINK1 PTK6

6.69e-061983156328_UP
DrugClindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A

TINAGL1 CITED2 TNIK RIN3 MINK1

6.69e-061983155815_UP
Drugvandetanib

TNIK EPHA6 PTK6 EPHA7

9.67e-0699314CID003081361
Drugcolumbamine

EPHB2 STAT3

5.00e-058312ctd:C055786
DrugBIRB796

TNIK EPHA6 EPHA7

9.87e-0566313CID000156422
Drugponatinib

EPHB2 PTK6 EPHA7

1.08e-0468313ctd:C545373
DrugHelveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A

TINAGL1 PRICKLE3 MINK1 PTK6

1.12e-041853144327_DN
DrugMexiletine hydrochloride [5370-01-4]; Down 200; 18.6uM; PC3; HT_HG-U133A

TINAGL1 MINK1 PTK6 EPHA7

1.32e-041933144338_DN
DrugHaloperidol [52-86-8]; Down 200; 10.6uM; PC3; HT_HG-U133A

EPHB2 RIN3 FAM222B PTK6

1.34e-041943144678_DN
DrugCefotiam hydrochloride; Down 200; 7.2uM; PC3; HT_HG-U133A

EPHB2 TINAGL1 CITED2 PRICKLE3

1.37e-041953146762_DN
DrugAsiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A

EPHB2 NBEAL2 MINK1 PTK6

1.37e-041953143504_DN
DrugIsoetharine mesylate salt [7279-75-6]; Down 200; 12uM; MCF7; HT_HG-U133A

EPHB2 PRICKLE3 NBEAL2 MINK1

1.37e-041953143451_DN
DrugRapamycin; Up 200; 0.1uM; HL60; HT_HG-U133A

NR4A3 RIN3 NR6A1 PRICKLE3

1.37e-041953141162_UP
DrugAmoxapine [14028-44-5]; Down 200; 12.8uM; PC3; HT_HG-U133A

EPHB2 TNIK RIN3 MINK1

1.37e-041953146650_DN
DrugClomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A

EPHB2 TINAGL1 TNIK RIN3

1.37e-041953146648_DN
Drug(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; HL60; HT_HG-U133A

NR4A3 RIN3 NBEAL2 MINK1

1.40e-041963143121_DN
DrugHydrocortisone base [50-23-7]; Down 200; 11uM; MCF7; HT_HG-U133A

EPHB2 NR6A1 PRICKLE3 MINK1

1.40e-041963143284_DN
Drugnovobiocin sodium, USP; Down 200; 100uM; ssMCF7; HG-U133A

TNIK NR4A3 C11orf24 MAP4K4

1.40e-04196314499_DN
DrugLiothyronine [6893-02-3]; Down 200; 6.2uM; PC3; HT_HG-U133A

EPHB2 RIN3 NFIC PTK6

1.40e-041963146602_DN
DrugNisoxetine hydrochloride [57754-86-6]; Down 200; 13uM; PC3; HT_HG-U133A

EPHB2 TNIK RIN3 FAM222B

1.40e-041963145091_DN
DrugGlutethimide, para-amino [125-84-8]; Down 200; 17.2uM; MCF7; HT_HG-U133A

EPHB2 PRICKLE3 FAM222B MINK1

1.42e-041973147463_DN
DrugUngerine nitrate; Up 200; 10.2uM; PC3; HT_HG-U133A

EPHB2 TINAGL1 NR6A1 PRICKLE3

1.42e-041973145816_UP
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; PC3; HT_HG-U133A

TNIK PRICKLE3 NFIC FAM222B

1.42e-041973145746_DN
DrugMiconazole [22916-47-8]; Down 200; 9.6uM; HL60; HG-U133A

C11orf24 MAP4K4 NFIC FAM222B

1.45e-041983141977_DN
DrugTrichlorfon [52-68-6]; Down 200; 15.6uM; PC3; HT_HG-U133A

EPHB2 PRICKLE3 MINK1 PTK6

1.45e-041983141797_DN
DrugIobenguane sulfate; Up 200; 10.8uM; PC3; HT_HG-U133A

EPHB2 TINAGL1 PRICKLE3 EPHA7

1.45e-041983147299_UP
DrugNifedipine [21829-25-4]; Down 200; 11.6uM; PC3; HT_HG-U133A

CITED2 PRICKLE3 NBEAL2 MINK1

1.45e-041983147303_DN
DrugMethacycline hydrochloride [3963-95-9]; Down 200; 8.4uM; PC3; HT_HG-U133A

EPHB2 TNIK RIN3 PTK6

1.45e-041983144062_DN
Drug(-)-MK 801 hydrogen maleate [77086-19-2]; Down 200; 11.8uM; MCF7; HT_HG-U133A

EPHB2 NFIC NBEAL2 PTK6

1.48e-041993145003_DN
DrugOrphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A

EPHB2 FAM222B MINK1 PTK6

1.48e-041993144537_DN
Drugestradiol, USP; Down 200; 0.01uM; PC3; HT_HG-U133A

EPHB2 TINAGL1 PRICKLE3 PTK6

1.48e-041993141241_DN
DrugCefamandole sodium salt [30034-03-8]; Down 200; 8.2uM; PC3; HT_HG-U133A

TINAGL1 RIN3 MINK1 PTK6

1.48e-041993143696_DN
DrugCAY10397; Up 200; 10uM; MCF7; HT_HG-U133A

NR6A1 FAM222B MINK1 PTK6

1.51e-042003147082_UP
DrugEKB-569

TNIK EPHA6 STAT3

2.24e-0487313CID006445562
Diseaseepilepsy (implicated_via_orthology)

TNIK PRICKLE3 MAP4K4 MINK1

2.86e-05163324DOID:1826 (implicated_via_orthology)
DiseaseEye Abnormalities

SH3PXD2B FREM1

1.53e-0417322C0015393
DiseaseCongenital hernia of foramen of Morgagni

FREM1 STAT3

1.93e-0419322C0265699
DiseaseCongenital hernia of foramen of Bochdalek

FREM1 STAT3

1.93e-0419322C0265700
Diseaseserum homoarginine measurement

TINAGL1 AGXT2

2.14e-0420322EFO_0005421
DiseaseCongenital diaphragmatic hernia

FREM1 STAT3

2.36e-0421322C0235833
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

TNIK NR4A3 STAT3

3.86e-04131323C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

TNIK NR4A3 STAT3

3.86e-04131323C4552091
DiseaseJuvenile arthritis

TNIK NR4A3 STAT3

3.86e-04131323C3495559
DiseaseJuvenile psoriatic arthritis

TNIK NR4A3 STAT3

3.86e-04131323C3714758
DiseaseJuvenile-Onset Still Disease

TNIK NR4A3 STAT3

4.22e-04135323C0087031
Diseaseserum metabolite measurement

TINAGL1 TNIK AGXT2 EPHA6 STAT3 EPHA7

4.72e-04945326EFO_0005653
Diseasecortical surface area measurement

TINAGL1 ZNF438 TNIK RIN3 NYAP2 MAP4K4 EPHA7

4.97e-041345327EFO_0010736
Diseaseimmunoglobulin isotype switching measurement

RIN3 STAT3

1.05e-0344322EFO_0010128
Diseasecortical thickness

ZNF438 TNIK SH3PXD2B RIN3 NYAP2 EPHA7

1.11e-031113326EFO_0004840
Diseasesevere acute respiratory syndrome, COVID-19

EPHB2 RIN3 FAM222B EPHA7

1.34e-03447324EFO_0000694, MONDO_0100096
Diseasebody fat percentage

RIN3 IGSF9B NYAP2 RPTOR

1.84e-03488324EFO_0007800
Diseasechronic kidney disease

TINAGL1 RIN3 EPHA7

2.09e-03235323EFO_0003884

Protein segments in the cluster

PeptideGeneStartEntry
SLHTKPRMPPCDFMP

AGXT2

41

Q9BYV1
MAECKAQMHLLPSPP

DNHD1

4376

Q96M86
MAEGAPPLCDMHPMR

MAP4K4

226

O95819
MAMRLHFQPPHPNCL

CFAP65

711

Q6ZU64
PPPMDCPSALHQLML

EPHB2

846

P29323
MDATIAPHRIPPEMP

AK8

1

Q96MA6
PTPMPSCVVNPMEHT

FAM222B

316

Q8WU58
VAYMPPMQDIGPHCR

FREM1

731

Q5H8C1
FMTMPAPQDRLPHPC

NYAP2

96

Q9P242
PAPMDCPAGLHQLML

EPHA7

856

Q15375
MPCPLECPPSVHKLM

PTK6

406

Q13882
PPHLCRPMPAQDTAM

PRICKLE3

571

O43900
SMCPATTDGRPRPPM

FOXS1

176

O43638
PMHPCRPPTQRRMAA

OR8A1

6

Q8NGG7
CEMEGNLEHLPPPPM

PCARE

821

A6NGG8
DHPNQPPMMTCERLP

RIN3

331

Q8TB24
PAPMGCPASLHQLML

EPHA6

896

Q9UF33
MAEGAPPLCDMHPMR

MINK1

226

Q8N4C8
PPSPPICMMNALVRA

NR4A3

391

Q92570
THQPNRFPDLMMCLP

NR6A1

431

Q15406
DEAGPAPPCMMHSRA

TINAGL1

301

Q9GZM7
NMAVEGDHSMCPPPP

NBEAL2

431

Q6ZNJ1
KMPSHCLSAQMLAPP

NFIC

431

P08651
HPLAQMPLPPSMKNC

RPTOR

226

Q8N122
MPASVAHVPAAMLPP

CITED2

201

Q99967
HMPSDTAASPVPPMR

C11orf24

236

Q96F05
MAEGAPPLCDMHPMR

TNIK

226

Q9UKE5
ETPAMMFPHQLPPCD

IGSF9B

1051

Q9UPX0
LPMMPAKHIPPARDS

SH3PXD2B

561

A1X283
QPCMPMHPDRPLVIK

STAT3

326

P40763
AQLHSVAMPFPPMAP

SCART1

736

Q4G0T1
AQTQMCPQMSPSPPH

ZNF438

151

Q7Z4V0