Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsynaptobrevin 2-SNAP-25-syntaxin-3-complexin complex

CPLX2 CPLX1

1.34e-052772GO:0070554
GeneOntologyCellularComponentdystroglycan complex

SGCB DAG1

2.78e-047772GO:0016011
GeneOntologyCellularComponentcalyx of Held

CPLX2 CPLX1 PRKCA

3.14e-0436773GO:0044305
GeneOntologyCellularComponentaxon

SIRT2 SPG7 MYH14 CPLX2 EIF4G2 CPLX1 DAG1 PRKCA CNGB1 SLC1A2 SLC17A6

4.04e-048917711GO:0030424
DomainSynaphin

CPLX2 CPLX1

9.75e-054762IPR008849
DomainSynaphin

CPLX2 CPLX1

9.75e-054762PF05835
DomainMyosin_N

MYH13 MYH14

1.66e-0315762PF02736
DomainMyosin_N

MYH13 MYH14

1.66e-0315762IPR004009
DomainMyosin_tail_1

MYH13 MYH14

2.40e-0318762PF01576
DomainMyosin_tail

MYH13 MYH14

2.40e-0318762IPR002928
DomainMyosin-like_IQ_dom

MYH13 MYH14

2.67e-0319762IPR027401
Domain-

MYH13 MYH14

2.67e-03197624.10.270.10
DomainC2

HECW1 PLCH2 PRKCA PRKCQ

2.69e-03142764PS50004
Domain-

HECW1 PLCH2 PRKCA PRKCQ

3.12e-031487642.60.40.150
DomainDAG/PE-bd

PRKCA PRKCQ

3.26e-0321762IPR020454
DomainC2_dom

HECW1 PLCH2 PRKCA PRKCQ

4.50e-03164764IPR000008
PathwayKEGG_VIRAL_MYOCARDITIS

MYH13 MYH14 SGCB EIF4G2 DAG1

1.85e-0570665M12294
Pubmed

Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity.

RORB PRKCQ TFAP2B SLC17A6

6.64e-081877423616538
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

GMPS PTPN2 MAGED1 ACACA HECW1 EIF4G2 CPLX1 DAG1 PRKCA POLD3 PYCR2 GCN1 SLC1A2 DDX39B

1.85e-071139771436417873
Pubmed

Structurally and functionally unique complexins at retinal ribbon synapses.

CPLX2 CPLX1 PRKCA

3.63e-07777315911881
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

SLC12A2 DSC3 CARMIL1 EIF4G2 DAG1 GCN1 DDX39B PACSIN2 NOTCH3 TP53BP2

4.89e-07565771025468996
Pubmed

Presynaptic proteins complexin-I and complexin-II differentially influence cognitive function in early and late stages of Alzheimer's disease.

CPLX2 CPLX1

4.84e-06277227866231
Pubmed

Complexin controls the force transfer from SNARE complexes to membranes in fusion.

CPLX2 CPLX1

4.84e-06277219164751
Pubmed

Complexin facilitates exocytosis and synchronizes vesicle release in two secretory model systems.

CPLX2 CPLX1

4.84e-06277223401610
Pubmed

Differential involvement of vesicular and glial glutamate transporters around spinal α-motoneurons in the pathogenesis of SOD1G93A mouse model of amyotrophic lateral sclerosis.

SLC1A2 SLC17A6

4.84e-06277228526579
Pubmed

Protein kinase C phosphorylates G12 alpha and inhibits its interaction with G beta gamma.

PRKCA GNA12

4.84e-0627728647866
Pubmed

PKC theta cooperates with PKC alpha in alloimmune responses of T cells in vivo.

PRKCA PRKCQ

4.84e-06277219356803
Pubmed

No association of complexin1 and complexin2 genes with schizophrenia in a Japanese population.

CPLX2 CPLX1

4.84e-06277216442780
Pubmed

Distinct regional distribution in the brain of messenger RNAs for the two isoforms of synaphin associated with the docking/fusion complex.

CPLX2 CPLX1

4.84e-06277210051208
Pubmed

Complexins regulate a late step in Ca2+-dependent neurotransmitter release.

CPLX2 CPLX1

4.84e-06277211163241
Pubmed

[The mechanism of neurotransmitter release: role of synaphin/complexin in synaptic vesicle exocytosis].

CPLX2 CPLX1

4.84e-06277212058476
Pubmed

PKCα phosphorylation of GLT-1 at Ser562/563 induces glutamate excitotoxicity in ischemia in mice.

PRKCA SLC1A2

4.84e-06277235318310
Pubmed

Na(+)-K(+)-2Cl(-) cotransporter-mediated fluid secretion increases under hypotonic osmolarity in the mouse submandibular salivary gland.

SLC12A2 SLC1A2

4.84e-06277224623142
Pubmed

Protein kinase C (PKC) alpha and PKC theta are the major PKC isotypes involved in TCR down-regulation.

PRKCA PRKCQ

4.84e-06277216751397
Pubmed

Altered immunoreactivity of complexin protein in prefrontal cortex in severe mental illness.

CPLX2 CPLX1

4.84e-06277212082566
Pubmed

Phosphorylation of PACSIN2 by protein kinase C triggers the removal of caveolae from the plasma membrane.

PRKCA PACSIN2

4.84e-06277226092940
Pubmed

Regulation of complexin 1 and complexin 2 in the developing human prefrontal cortex.

CPLX2 CPLX1

4.84e-06277218240322
Pubmed

Identification of two highly homologous presynaptic proteins distinctly localized at the dendritic and somatic synapses.

CPLX2 CPLX1

4.84e-0627727635198
Pubmed

Complexin stabilizes newly primed synaptic vesicles and prevents their premature fusion at the mouse calyx of held synapse.

CPLX2 CPLX1

4.84e-06277226019341
Pubmed

Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice.

PRKCA PRKCQ

4.84e-06277223908466
Pubmed

Preferential involvement of excitatory neurons in medial temporal lobe in schizophrenia.

CPLX2 CPLX1

4.84e-0627729853440
Pubmed

Postsynaptic complexin controls AMPA receptor exocytosis during LTP.

CPLX2 CPLX1

4.84e-06277222284181
Pubmed

Differential messenger RNA expression of complexins in mouse brain.

CPLX2 CPLX1

4.84e-06277215121237
Pubmed

Cerebellar synaptic protein expression in schizophrenia.

CPLX2 CPLX1

4.84e-06277211483314
Pubmed

Deconstructing complexin function in activating and clamping Ca2+-triggered exocytosis by comparing knockout and knockdown phenotypes.

CPLX2 CPLX1

4.84e-06277224297916
Pubmed

Temporal profiling of photoreceptor lineage gene expression during murine retinal development.

SALL3 RORB PRDM1

9.86e-061977328288836
Pubmed

Sox2 modulates the function of two distinct cell lineages in mouse skin.

KRT20 SLC17A6 PRDM1

1.35e-052177323948231
Pubmed

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis.

SIRT2 PRDM1

1.45e-05377237385228
Pubmed

Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin.

CPLX2 CPLX1

1.45e-05377231501440
Pubmed

Inhibition of glycogen synthesis by fatty acid in C(2)C(12) muscle cells is independent of PKC-alpha, -epsilon, and -theta.

PRKCA PRKCQ

1.45e-05377212006349
Pubmed

Complexins facilitate neurotransmitter release at excitatory and inhibitory synapses in mammalian central nervous system.

CPLX2 CPLX1

1.45e-05377218505837
Pubmed

Tilting the balance between facilitatory and inhibitory functions of mammalian and Drosophila Complexins orchestrates synaptic vesicle exocytosis.

CPLX2 CPLX1

1.45e-05377219914185
Pubmed

Age-related changes in dystrophin-glycoprotein complex and in utrophin are not correlated with intrinsic laryngeal muscles protection in mdx mice.

SGCB DAG1

1.45e-05377222102469
Pubmed

Regulation of retinoid X receptor responsive element-dependent transcription in T lymphocytes by Ser/Thr phosphatases: functional divergence of protein kinase C (PKC)theta; and PKC alpha in mediating calcineurin-induced transactivation.

PRKCA PRKCQ

1.45e-05377212097375
Pubmed

Quantitative proteome analysis of detergent-resistant membranes identifies the differential regulation of protein kinase C isoforms in apoptotic T cells.

PRKCA PRKCQ

1.45e-05377220486122
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

IVD MYH13 GUCY1A2 MYH14 CPLX2 CPLX1 KRT20 GNA12 PABPC5 PYCR2 POLQ DDX39B SLC17A6

1.57e-051442771335575683
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ABCA3 SIRT2 TPCN2 MAGED1 SPG7 SGCB PLCH2 CPLX1 GNA12

2.37e-0569777928298427
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

MAGED1 ACACA GLDC PSMB3 EIF4G2 POLD3 PYCR2 GCN1

2.44e-0553477835032548
Pubmed

Acute Complexin Knockout Abates Spontaneous and Evoked Transmitter Release.

CPLX2 CPLX1

2.89e-05477230840877
Pubmed

Expression of the synaptic exocytosis-regulating molecule complexin 2 in taste buds and its participation in peripheral taste transduction.

CPLX2 CPLX1

2.89e-05477225692331
Pubmed

Complexin-I is required for high-fidelity transmission at the endbulb of Held auditory synapse.

CPLX2 CPLX1

2.89e-05477219553439
Pubmed

Protein kinase C activation inhibits tyrosine phosphorylation of Cbl and its recruitment of Src homology 2 domain-containing proteins.

PRKCA PRKCQ

2.89e-05477210358153
Pubmed

Differential regulation of Moraxella catarrhalis-induced interleukin-8 response by protein kinase C isoforms.

PRKCA PRKCQ

2.89e-05477218184679
Pubmed

Notch3 and canonical NF-kappaB signaling pathways cooperatively regulate Foxp3 transcription.

PRKCQ NOTCH3

2.89e-05477221508258
Pubmed

Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

SALL3 PRKCA TFAP2B

4.06e-053077330127719
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

GMPS ACACA DSC3 MYH14 PSMB3 EIF4G2 PRKCA POLD3 PYCR2 GCN1 DDX39B TP53BP2

4.06e-051353771229467282
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

IVD GMPS PTPN2 MAGED1 ACACA DSC3 PTGR1 PSMB3 EIF4G2 DAG1 PRKCA GCN1

4.48e-051367771232687490
Pubmed

The interaction of protein kinase C isozymes alpha, iota, and theta with the cytoplasmic domain of L-selectin is modulated by phosphorylation of the receptor.

PRKCA PRKCQ

4.82e-05577215192100
Pubmed

Expression of the dystrophin-glycoprotein complex is a marker for human airway smooth muscle phenotype maturation.

SGCB DAG1

4.82e-05577217993586
Pubmed

Action of complexin on SNARE complex.

CPLX2 CPLX1

4.82e-05577212200427
Pubmed

Novel (n)PKC kinases phosphorylate Nef for increased HIV transcription, replication and perinuclear targeting.

PRKCA PRKCQ

4.82e-05577217904606
Pubmed

Molecular organization of sarcoglycan complex in mouse myotubes in culture.

SGCB DAG1

4.82e-0557729864373
Pubmed

Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening.

SALL3 RORB TFAP2B

4.94e-053277316516881
Pubmed

Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.

SIRT2 DSC3 PTGR1 GLDC PSMB3 DDX39B

5.98e-0530477632235678
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

MAGED1 ACACA HECW1 MYH14 SERPINE1 PYCR2 TP53BP2 PRDM1

6.08e-0560877816713569
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SIRT2 GUCY1A2 MYH14 CARMIL1 PSMB3 EIF4G2 PRKCA PYCR2 SLC1A2 DDX39B HCK TP53BP2

6.95e-051431771237142655
Pubmed

Protein kinase C isoform expression and activity in the mouse heart.

PRKCA PRKCQ

7.22e-05677211668067
Pubmed

Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases.

PRKCA PRKCQ

7.22e-05677211788586
Pubmed

Oculomotor deficits in aryl hydrocarbon receptor null mouse.

PRKCA SLC17A6

7.22e-05677223301081
Pubmed

A conformational switch in syntaxin during exocytosis: role of munc18.

CPLX2 CPLX1

7.22e-05677210449403
Pubmed

Reactive astrogliosis causes the development of spontaneous seizures.

SLC12A2 SLC1A2

7.22e-05677225716834
Pubmed

Protein kinase C-theta is specifically localized on centrosomes and kinetochores in mitotic cells.

PRKCA PRKCQ

7.22e-0567729854032
Pubmed

Comparative gene expression analysis of genital tubercle development reveals a putative appendicular Wnt7 network for the epidermal differentiation.

DSC3 TFAP2B PRDM1

7.68e-053777320510229
Pubmed

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.

SGCB DAG1

1.01e-0477721461282
Pubmed

Functional association of cytokine-induced SH2 protein and protein kinase C in activated T cells.

PRKCA PRKCQ

1.01e-04777212618484
Pubmed

Gene-environment interaction in the etiology of mathematical ability using SNP sets.

ARID1B GUCY1A2

1.01e-04777220978832
Pubmed

Sarcoglycan complex: implications for metabolic defects in muscular dystrophies.

SGCB DAG1

1.01e-04777219494113
Pubmed

A synaptic filtering mechanism in visual threat identification in mouse.

RORB SLC17A6

1.01e-04777236574675
Pubmed

14-3-3Gamma interacts with and is phosphorylated by multiple protein kinase C isoforms in PDGF-stimulated human vascular smooth muscle cells.

PRKCA PRKCQ

1.01e-04777210433554
Pubmed

Syk kinase-coupled C-type lectin receptors engage protein kinase C-δ to elicit Card9 adaptor-mediated innate immunity.

PRKCA PRKCQ

1.01e-04777222265677
Pubmed

QM, a putative tumor suppressor, regulates proto-oncogene c-yes.

PRKCA HCK

1.01e-04777212138090
Pubmed

Biochemical evidence for association of dystrobrevin with the sarcoglycan-sarcospan complex as a basis for understanding sarcoglycanopathy.

SGCB DAG1

1.01e-04777210767327
Pubmed

SNAREs and traffic.

CPLX2 CPLX1

1.01e-04777215893389
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IVD PTPN2 SIRT2 SLC12A2 LUC7L3 ALDH1L2 PSMB3 MTR PRKCQ ARMCX4 PYCR2 DDX39B

1.06e-041496771232877691
Pubmed

epsilon-sarcoglycan replaces alpha-sarcoglycan in smooth muscle to form a unique dystrophin-glycoprotein complex.

SGCB DAG1

1.34e-04877210488149
Pubmed

Ki-1/57 interacts with RACK1 and is a substrate for the phosphorylation by phorbol 12-myristate 13-acetate-activated protein kinase C.

PRKCA PRKCQ

1.34e-04877214699138
Pubmed

Distribution of the extended family of protein kinase C isoenzymes in fetal organs of mice: an immunohistochemical study.

PRKCA PRKCQ

1.34e-0487727606770
Pubmed

Protein kinase C phosphorylation of the metabotropic glutamate receptor mGluR5 on Serine 839 regulates Ca2+ oscillations.

PRKCA PRKCQ

1.34e-04877215894802
Pubmed

Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy.

SGCB DAG1

1.34e-04877210481911
Pubmed

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.

DAG1 PRKCQ PACSIN2

1.48e-044677323793062
Pubmed

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

ACACA MYH14 PSMB3 GNA12 GCN1

1.66e-0423177536597993
Pubmed

Regulation of HIV-1 gag protein subcellular targeting by protein kinase C.

PRKCA PRKCQ

1.72e-0497727876252
Pubmed

Phosphorylation of HIV-1 gag proteins by protein kinase C.

PRKCA PRKCQ

1.72e-0497728473314
Pubmed

Inhibition of protein kinase C by a synthetic peptide corresponding to cytoplasmic domain residues 828-848 of the human immunodeficiency virus type 1 envelope glycoprotein.

PRKCA PRKCQ

1.72e-0497727850771
Pubmed

Human immunodeficiency virus-1 recombinant gp120 induces changes in protein kinase C isozymes--a preliminary report.

PRKCA PRKCQ

1.72e-0497728206685
Pubmed

Complexins: cytosolic proteins that regulate SNAP receptor function.

CPLX2 CPLX1

1.72e-0497727553862
Pubmed

The phorbol ester TPA strongly inhibits HIV-1-induced syncytia formation but enhances virus production: possible involvement of protein kinase C pathway.

PRKCA PRKCQ

2.15e-04107721970444
Pubmed

Regulation of highly cytokinergic IgE-induced mast cell adhesion by Src, Syk, Tec, and protein kinase C family kinases.

PRKCQ HCK

2.15e-041077215814670
Pubmed

Distinct Functions of Syntaxin-1 in Neuronal Maintenance, Synaptic Vesicle Docking, and Fusion in Mouse Neurons.

CPLX2 CPLX1

2.15e-041077227466336
Pubmed

Human immunodeficiency virus induces phosphorylation of its cell surface receptor.

PRKCA PRKCQ

2.15e-04107723259291
Pubmed

Effect of serine and tyrosine phosphorylation on retroviral proteinase substrates.

PRKCA PRKCQ

2.15e-041077210491200
Pubmed

Inhibition of protein kinase C and anti-CD3-induced Ca2+ influx in Jurkat T cells by a synthetic peptide with sequence identity to HIV-1 gp41.

PRKCA PRKCQ

2.15e-04107722139676
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

GMPS MAGED1 ACACA LUC7L3 PSMB3 POLD3 PYCR2 GCN1 DDX39B PACSIN2

2.20e-041149771035446349
Pubmed

Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol.

PRKCA PRKCQ

2.63e-041177214613966
Pubmed

IL-16- and other CD4 ligand-induced migration is dependent upon protein kinase C.

PRKCA PRKCQ

2.63e-04117728599832
Pubmed

The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.

CPLX2 CPLX1

2.63e-041177225374362
Pubmed

Trans-activation of HIV-1 LTR-directed gene expression by tat requires protein kinase C.

PRKCA PRKCQ

2.63e-04117722182321
GeneFamilyC2 domain containing protein kinases

PRKCA PRKCQ

3.74e-0410532835
GeneFamilyMyosin heavy chains

MYH13 MYH14

8.64e-04155321098
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

SLC12A2 POLD3 PREX2 TP53BP2

1.94e-03181534694
GeneFamilyDNA polymerases

POLD3 POLQ

2.05e-0323532535
GeneFamilySolute carriers

SLC26A3 SLC12A2 SLC25A16 SLC1A2 SLC17A6

5.89e-03395535752
CoexpressionGSE41978_WT_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP

STYX PTGR1 MYH14 SGCB SEL1L2 DENND2B HCK

2.08e-06200777M9562
CoexpressionTRAVAGLINI_LUNG_PERICYTE_CELL

SLC12A2 GUCY1A2 PREX2 NOTCH3 PRDM1

2.19e-05114775M41678
CoexpressionGSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN

ARID1B PLCH2 DAG1 TFAP2B NOTCH3 TP53BP2

2.69e-05199776M7319
CoexpressionGSE8835_HEALTHY_VS_CLL_CD8_TCELL_DN

PTPN2 MAGED1 ALDH1L2 SERPINE1 RPE SLC1A2

2.77e-05200776M6263
CoexpressionGSE2585_CTEC_VS_THYMIC_MACROPHAGE_UP

PTPN2 MAGED1 ALDH1L2 PYCR2 RPE SLC1A2

2.77e-05200776M6268
CoexpressionGSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP

GMPS PTGR1 UBD MTR HSD11B1 SLC25A16

2.77e-05200776M7519
ToppCellwk_15-18-Epithelial-PNS-MFNG+_DBH+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 RORB SEL1L2 CNGB1 TFAP2B

8.56e-0718677672f7427d62d65e37bb0bf99229a1b75df081a128
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B EML5 HECW1 CPLX2 CNGB1

1.36e-05176775116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B EML5 GUCY1A2 CPLX2 CNGB1

1.36e-0517677504dad262929581872e5bbc66cd8182c963e7e52f
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B EML5 HECW1 CPLX2 CNGB1

1.36e-051767755b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLDC NEXMIF PRKCA HSD11B1 NOTCH3

1.48e-05179775e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GUCY1A2 SGCB NEXMIF DENND2B PREX2

1.48e-05179775a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B EML5 HECW1 CPLX1 TFAP2B

1.52e-051807753d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 CPLX2 CNGB1 TFAP2B

1.64e-051837759dfb398b9995d562864fe688861a831ada0814cd
ToppCellwk_08-11-Epithelial-PNS-PCP4+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 NEXMIF CPLX2 TFAP2B

1.69e-05184775eac2a9089913f33a961ba11519b53645790f2056
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

SPTLC3 ARID1B GLDC CARMIL1 PRKCA

1.78e-05186775de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B EML5 HECW1 CDKL2 CNGB1

1.78e-0518677524b23880d4ff8fb4a23e2012d5890b9e2fcf7283
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

SPTLC3 ARID1B GLDC CARMIL1 PRKCA

1.78e-051867750b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B PLCH2 CPLX2 CPLX1 TFAP2B

1.82e-05187775ef3c85c01bc3da408ae288b6e3096ad888a12e63
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 PTGR1 GLDC PLCH2 KRT20

1.82e-0518777574112df9b34051ae5cd2427ccfa3399eccff0076
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MTR DAG1 PRKCQ HSD11B1 NOTCH3

1.82e-0518777569b47f00598d647e2a99427ebddf42c339428e47
ToppCellfacs-Lung-EPCAM-24m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 PTGR1 GLDC PLCH2 KRT20

1.82e-05187775214ce9b55fd6ce2fe7bd4cf4b1383517f5f0d759
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA3 SLC12A2 ACACA MYH14 NEXMIF

1.87e-05188775b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCellfacs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA3 SLC12A2 ACACA MYH14 NEXMIF

1.87e-051887753dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B HECW1 PLCH2 CPLX2 CPLX1

1.92e-051897753d838da870623a6a278ddc8e6cedca85d9877e50
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ABCA3 EML5 CPLX2 CNGB1

1.92e-05189775cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL3 GLDC RORB HSD11B1 SLC1A2

2.02e-05191775fd345837bfc40d85256b9a7e4fd3343bcbfe0ae5
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLDC RORB HSD11B1 SLC1A2 PREX2

2.07e-05192775d2161842a38146261847fc9061ba9322e0f087e0
ToppCelldroplet-Fat-Scat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 SLC12A2 MYH14 PLCH2 TFAP2B

2.07e-051927754098b5170c9995718758a082d1b8bcb86d5a289e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLDC RORB HSD11B1 SLC1A2 PREX2

2.07e-05192775261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCelldroplet-Fat-Scat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 SLC12A2 MYH14 PLCH2 TFAP2B

2.07e-05192775936028fe851e8dd2b906df0210acc574c017b499
ToppCelldroplet-Fat-Scat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 SLC12A2 MYH14 PLCH2 TFAP2B

2.07e-0519277562e55ed0d46b2e7b07dc42399972a099576cbc5f
ToppCellCOVID-19_Severe-Plasmablast|World / disease group, cell group and cell class

MAGED1 GLDC ALDH1L2 POLQ PRDM1

2.07e-05192775a333053fe2bd206c32790916bfc5fce904ab7f57
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA3 SLC12A2 MYH13 MYH14 NEXMIF

2.07e-0519277513e4b17d7a592604140777aca235f795df6b3f91
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA3 SLC12A2 MYH13 MYH14 NEXMIF

2.07e-05192775f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA3 SLC12A2 MYH13 MYH14 NEXMIF

2.07e-051927756244541688f85917018a057aa0b3e5972934dfbc
ToppCellwk_15-18-Epithelial-PNS|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 RORB CNGB1 TFAP2B

2.12e-05193775ca65f8f93058ad50d89e69e06c10deeb46dbfc87
ToppCellCOVID-19_Severe-Plasmablast|COVID-19_Severe / disease group, cell group and cell class

MAGED1 GLDC ALDH1L2 POLQ PRDM1

2.12e-051937758074bcede261b85f9ae03ee372bd6d4b40384537
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 MYH14 GLDC CNGB1

2.17e-05194775c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ABCA3 ACACA CARMIL1 PRKCQ PACSIN2

2.17e-0519477597534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A2 SERPINE1 PRKCA HSD11B1 SLC1A2

2.28e-05196775ba869f7a86f37fd6d84d6ad69baca0e0faaf5887
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GUCY1A2 SERPINE1 PRKCA HSD11B1 SLC1A2

2.28e-0519677530ad56d49000e4ddce73b4443b3994564bd1e2d6
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

TLCD3B CPLX2 CNGB1 TFAP2B SLC17A6

2.34e-05197775c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B ABCA3 EML5 CPLX2 CNGB1

2.40e-0519877550504a3871f76d6a5b439a56450d7770f4501eb0
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SGCB DAG1 PABPC5 DENND2B NOTCH3

2.40e-0519877555e583321f60c95898d93cd0d2615c6692db52ec
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPTLC3 ABCA3 ACACA CDKL2 MYH14

2.46e-051997755f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SPTLC3 ABCA3 ACACA CDKL2 MYH14

2.46e-05199775725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA3 ACACA CDKL2 MYH14 PACSIN2

2.46e-051997758587bd98de7767a575088afbea07a1feb4516b9b
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SGCB DAG1 PABPC5 DENND2B NOTCH3

2.46e-05199775e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SGCB DAG1 PABPC5 DENND2B NOTCH3

2.46e-05199775801887db51ac5dc5b068808ff75e3a46643398e9
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Neuron|1m / Sample Type, Dataset, Time_group, and Cell type.

TLCD3B SGCB EIF4G2 TFAP2B SLC17A6

2.52e-05200775be1e153119ca4946b4eaef6037e8465f5c00ca6f
ToppCellPosterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PLIN4 PTGR1 SERPINE1 NOTCH3

5.60e-05120774a320799ab5f2ce872e038b15841a23174c5436e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Whrn_Tox2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KRT20 RORB HSD11B1 SLC17A6

1.11e-0414377436ce6f163fb33141c86288086c354b91853fad25
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A2 PTGR1 CPLX2 SLC17A6

1.14e-041447741d05aa08603cba28c0c6511767e434c1f592a3aa
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A2 CARMIL1 HSD11B1 NOTCH3

1.14e-04144774121853910eeea1ea0642b3cc99f9200015480368
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GUCY1A2 PTGR1 CPLX2 SLC17A6

1.14e-04144774d3f6f5da56794367ee3776bfd3a9dcf893efe0f0
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SALL3 GLDC HSD11B1 PREX2

1.43e-0415377495b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SALL3 GLDC HSD11B1 PREX2

1.43e-04153774b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCellprimary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SALL3 GLDC HSD11B1 PREX2

1.43e-041537743ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UBD CPLX1 PABPC5 CNGB1

1.47e-041547741899138c096c08d8aee6b1970b7c0081e14c88a8
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

SLC12A2 SERPINE1 DENND2B PRDM1

1.58e-0415777484f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 CARMIL1 PRKCA NOTCH3

1.58e-04157774fc127e7720649e746f3d3f5c2e9e63784767106a
ToppCellfacs-GAT-Fat-24m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBD HSD11B1 TFAP2B PRDM1

1.58e-04157774c4a0b6c95d353691fd2846002ce4bc7c2b0edd1c
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH13 CARMIL1 PRKCA NOTCH3

1.58e-0415777466a191cef4aa00811bb04462310d012610006f85
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MYH14 KRT20 RORB SLC17A6

1.66e-04159774a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A2 UBD GNA12 SLC1A2

1.70e-041607740544bc465af208da448858d6e174ff56f2e08a46
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 CPLX2 CPLX1 SLC17A6

1.74e-0416177469f5e759c0925daa37e0177a9cc3154842906bf6
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA3 SLC12A2 MYH14 NEXMIF

1.79e-0416277406f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCA3 SLC12A2 MYH14 NEXMIF

1.79e-04162774d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KRT20 RORB SLC1A2 SLC17A6

1.83e-041637741e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KRT20 RORB SLC1A2 SLC17A6

1.83e-04163774431221a41d396b09170476179590eaf8a55266d8
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

GUCY1A2 PRKCQ FN3K PRDM1

1.87e-0416477484a1808bc6f501218ac2a5a05eb188a07ccd3890
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 CPLX2 CPLX1 SLC17A6

1.92e-041657746d8b5669eee9b0903c9260fea707d186c9d7fefa
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 CPLX2 CPLX1 SLC17A6

1.92e-0416577402cd87dfa2ca40e13455a4b9308477e82f76289b
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_bronchial_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PLIN4 BRD9 CPLX1 PRDM1

1.96e-04166774a697460dfe72e08fbf7d8e734a16b7dd2c6d86f9
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLCD3B MAGED1 LUC7L3 PRKCA

1.96e-0416677466026988509e39e41274fa0de738383219e8ff30
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTLC3 SLC12A2 SEL1L2 NOTCH3

2.01e-0416777402c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 UBD CNGB1 SLC1A2

2.01e-041677748b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LUC7L3 CARMIL1 PRKCA HCK

2.05e-041687748072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLIN4 MAGED1 PABPC5 DENND2B

2.05e-04168774435ef2e4d702e978d54f9d1f5a047f39c691cc63
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GUCY1A2 PLCH2 RORB CNGB1

2.15e-041707743174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLIN4 PTGR1 MYH14 PLCH2

2.20e-0417177459b9dbaa05b6e5740edc633c9ce1181565550d5b
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

GUCY1A2 CARMIL1 PACSIN2 NOTCH3

2.20e-04171774e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PLIN4 PTGR1 MYH14 PLCH2

2.20e-04171774a5b9dd2b6a54db7962beeb5a9ceb9dacfb613fa7
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 CARMIL1 PRKCA NOTCH3

2.30e-041737744f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYH13 CARMIL1 PRKCA NOTCH3

2.30e-041737749bbea566964281f47bf75d665b7d69ba8326e207
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLIN4 CDKL2 SERPINE1 NOTCH3

2.35e-041747749f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACACA MYH14 CPLX2 NOTCH3

2.35e-04174774207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A2 DSC3 GUCY1A2 NOTCH3

2.40e-04175774d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellPosterior_cortex-Macroglia|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SIRT2 SALL3 GLDC PRKCQ

2.40e-041757748bc7a3856d04692989b2a1675ea6d9392261d55a
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A2 DSC3 GUCY1A2 NOTCH3

2.40e-04175774cf15465855602ba135752c18755e3e058dbd42ec
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SPTLC3 CNGB1 HCK

2.43e-04707732121ba6a0beb2a8fdc589ff1063e7d8c2c3c68f6
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SPTLC3 CNGB1 HCK

2.43e-0470773cd6bca68fe52f451716fc8c0b1745984bc9ec057
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

SPTLC3 CNGB1 HCK

2.43e-0470773be300c0447735aba89df4c3082b81eb5abf22770
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RORB HSD11B1 SLC1A2 PREX2

2.45e-04176774ac3dc44755280e36c0947b6de3cd639dc17de8b6
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA3 UBD GLDC CARMIL1

2.50e-04177774d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCellPCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 RORB TFAP2B

2.61e-04179774df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCellwk_15-18-Epithelial-PNS-KCNIP4+_neuron|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 NEXMIF CNGB1

2.61e-04179774e20bfdfb6d5af8556eb66b81a19fbe4e3e28334a
ToppCellPCW_13-14-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TLCD3B EML5 CPLX2 CNGB1

2.61e-04179774af0b54c9ea0b6e4210f22dbb6e88ecd3276a5f86
ToppCell390C-Fibroblasts-Fibroblast-G|390C / Donor, Lineage, Cell class and subclass (all cells)

LRRC34 ALDH1L2 NEXMIF HSD11B1

2.67e-04180774137fc14859c89e1ecd98bee388bb58c04b835847
ToppCell390C-Fibroblasts-Fibroblast-G-|390C / Donor, Lineage, Cell class and subclass (all cells)

LRRC34 ALDH1L2 NEXMIF HSD11B1

2.67e-04180774cd6790de050151fedfa2c5ea6ad58b72665414b2
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GUCY1A2 HSD11B1 POLD3 NOTCH3

2.73e-04181774274c0b768925cd5804483303f8c5ebd17a534c41
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ABCA3 MYH14 PRKCQ HSD11B1

2.73e-041817740513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TLCD3B EML5 CPLX2 CNGB1

2.73e-04181774fb4df9a128761abe5c6310a30d7b2f7f2fdef46d
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HECW1 GUCY1A2 CPLX2 DENND2B

2.73e-04181774d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

GUCY1A2 CARMIL1 PACSIN2 NOTCH3

2.78e-041827742075efeae633550fb2eb026d0dfd741c8252482e
DrugBAY 41-2272

GUCY1A2 SGCB SERPINE1 SLC17A6

7.34e-0637774CID009798973
DrugAC1L191M

DSC3 SGCB DAG1 RPE DDX39B

1.29e-0589775CID000000350
DrugDAPs

SGCB EIF4G2 DAG1 KRT20 PRKCA

1.52e-0592775CID000146339
DrugAC1L1AUZ

GMPS CDKL2 SGCB DAG1 KRT20 DENND2B

1.55e-05157776CID000001160
Drugtert-Butyl Alcohol

SLC12A2 PRKCA PRKCQ

2.02e-0516773ctd:D020002
Drugmethyl-coenzyme M

SGCB MTR DAG1

2.93e-0518773CID000000893
Drugeye gene

SLC12A2 MYH13 ACACA GUCY1A2 MYH14 SGCB PRKCA PRKCQ

3.51e-05369778CID000004782
Drugcreatine

PTPN2 MYH13 HECW1 MTR SLC1A2 SLC17A6

4.94e-05193776CID000000586
Drugamphetamine

PTPN2 SIRT2 ACACA CDKL2 PRKCA PRKCQ SLC17A6

4.98e-05284777CID000003007
DrugCarcinine [56897-53-1]; Up 200; 22uM; PC3; HT_HG-U133A

CDKL2 MYH14 PLCH2 EIF4G2 SLC17A6 PRDM1

5.38e-051967764225_UP
DrugMeprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; HL60; HT_HG-U133A

HECW1 ZNF862 PLCH2 SERPINE1 CNGB1 SLC1A2

6.02e-052007766123_UP
Drugpuerarin

GMPS SERPINE1 PRKCA PRKCQ

6.19e-0563774CID005281807
Drugbupivacaine

SGCB DAG1 KRT20 PRKCA PRKCQ

6.63e-05125775CID000002474
Drugglutathionyl 4-hydroxy-2-nonenal conjugate

PRKCA PRKCQ

6.74e-054772ctd:C524061
Drugflazin

SGCB DAG1

6.74e-054772CID005377686
DrugA8b

SGCB DAG1

6.74e-054772CID000656986
DrugN-methyl-DL-aspartic acid

PTPN2 TPCN2 GUCY1A2 CDKL2 SGCB EIF4G2 PRKCA PRKCQ SLC1A2 SLC17A6

7.01e-056557710CID000004376
DiseasePsychotic Disorders

SLC12A2 CPLX2 CPLX1 PRKCA GNA12

6.48e-06101765C0033975
DiseaseUlcerative Colitis

PTPN2 SLC26A3 GNA12 PRDM1

2.16e-0563764C0009324
DiseaseSchizoaffective Disorder

CPLX2 CPLX1 PRKCA

5.72e-0529763C0036337
DiseaseEpilepsy, Cryptogenic

ARID1B SLC12A2 NEXMIF SLC1A2

6.10e-0582764C0086237
DiseaseAwakening Epilepsy

ARID1B SLC12A2 NEXMIF SLC1A2

6.10e-0582764C0751111
DiseaseAura

ARID1B SLC12A2 NEXMIF SLC1A2

6.10e-0582764C0236018
Diseaseintestinal cancer (implicated_via_orthology)

PTPN2 HCK NOTCH3

7.72e-0532763DOID:10155 (implicated_via_orthology)
DiseaseEpilepsy

ARID1B SLC12A2 NEXMIF SLC1A2

1.84e-04109764C0014544
DiseaseMalignant neoplasm of breast

ARID1B ABCA3 DSC3 GUCY1A2 UBD MTR HSD11B1 NOTCH3 TP53BP2 SLC17A6

4.23e-0410747610C0006142
DiseaseBreast Carcinoma

ARID1B DSC3 GUCY1A2 UBD MTR NOTCH3 TP53BP2

4.76e-04538767C0678222
DiseaseMental Depression

CPLX2 CPLX1 MTR HSD11B1 SLC1A2

5.10e-04254765C0011570
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

SERPINE1 MTR DAG1 HSD11B1

5.74e-04147764DOID:9352 (biomarker_via_orthology)
DiseaseSchizophreniform Disorders

CPLX2 CPLX1

5.84e-0414762C0036358
DiseasePsychosis, Brief Reactive

CPLX2 CPLX1

5.84e-0414762C0033958
Diseasemyocardial infarction (implicated_via_orthology)

UBD SERPINE1 DAG1

6.69e-0466763DOID:5844 (implicated_via_orthology)
Diseaseuterine prolapse

SLC12A2 POLD3

7.67e-0416762EFO_1001864
DiseaseDepressive disorder

CPLX2 CPLX1 MTR HSD11B1 SLC1A2

9.12e-04289765C0011581
Diseaseischemia (biomarker_via_orthology)

ARID1B PRKCA

9.75e-0418762DOID:326 (biomarker_via_orthology)
DiseaseRheumatoid Arthritis

PTPN2 PRKCQ HSD11B1 PRDM1

1.08e-03174764C0003873
Diseasealcohol use disorder (implicated_via_orthology)

ARID1B BRD9 PRKCA NOTCH3

1.64e-03195764DOID:1574 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

ARID1B TPCN2 UBD CARMIL1 SERPINE1 PRKCA DENND2B

1.70e-03670767EFO_0006335, EFO_0006336
DiseaseSchizophrenia

SLC12A2 EML5 CPLX2 CPLX1 MTR PRKCA SLC1A2 SLC17A6

1.95e-03883768C0036341
DiseaseLimb-girdle muscular dystrophy

SGCB DAG1

2.04e-0326762cv:C0686353
DiseaseColorectal Carcinoma

ABCA3 SALL3 ACACA GUCY1A2 KRT20 POLD3 PREX2

2.21e-03702767C0009402
Diseasecognitive function measurement, self reported educational attainment

IVD ARID1B CARMIL1 GTDC1 TFAP2B

2.25e-03355765EFO_0004784, EFO_0008354
DiseaseMammary Carcinoma, Human

DSC3 GUCY1A2 UBD MTR NOTCH3 TP53BP2

2.35e-03525766C4704874
DiseaseMammary Neoplasms, Human

DSC3 GUCY1A2 UBD MTR NOTCH3 TP53BP2

2.35e-03525766C1257931
DiseaseMammary Neoplasms

DSC3 GUCY1A2 UBD MTR NOTCH3 TP53BP2

2.40e-03527766C1458155
Diseasemuscular atrophy (biomarker_via_orthology)

SERPINE1 DAG1

2.54e-0329762DOID:767 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
DGVVMCFGMKKGEAA

BBS7

41

Q8IWZ6
MQKGTGLLPFQGMDK

CPSF4L

21

A6NMK7
HAGFKMMSKQAALLG

BRD9

231

Q9H8M2
LGMDVLCQAKSGMGK

DDX39B

81

Q13838
KAVRMGMGAVFFNKG

ALDH1L2

711

Q3SY69
AMGAQLIGKFEAKGM

ABCA3

416

Q99758
GGMKDMYDQVLKFGA

ACACA

2051

Q13085
MGLGKDMGAQYAAAS

ARID1B

556

Q8NFD5
EEGSAQGVAMGMKFI

ANKRA2

41

Q9H9E1
QFVAQAGKLMGGLDM

HSD11B1

101

P28845
QSGMNKFLRGLGNKM

DENND2B

1116

P78524
KEGAGVDMKAQGMAQ

ARMCX4

501

Q5H9R4
FLYGVQEKMGIMNKG

TP53BP2

1046

Q13625
LMMNKDGFLGGMSVN

TFAP2B

211

Q92481
KEGFLGLYKGNGAMM

SLC25A16

86

P16260
KMGFMSVILVGAFVG

PTPN2

391

P17706
YNGGAVMAMKGKNCV

PSMB3

6

P49720
ADFGMCKENMLGDAK

PRKCQ

521

Q04759
MTGNKIENKGGMFFA

LRRC34

186

Q8IZ02
MAQKMDCGAGLLGFQ

MAGED1

1

Q9Y5V3
DFQAMGLKKGMFFNP

HECW1

211

Q76N89
FDMSAFMAGPGNAKK

DAG1

236

Q14118
MEFVMKQALGGATKD

CPLX1

1

O14810
KQALGGATKDMGKML

CPLX1

6

O14810
GFMDGKQACEKMIQA

MYH14

756

Q7Z406
PVGQDALGMKNMAKG

NOTCH3

1696

Q9UM47
ALGMKNMAKGESLMG

NOTCH3

1701

Q9UM47
LGSEGKVEEAQGMMK

LUC7L3

146

O95232
VSAKALGAMVKGMGE

GCN1

1676

Q92616
GQKIGHFQLMQGKMA

IVD

316

P26440
GGGDLFVGNEKMAMQ

KRT20

61

P35900
QFGEMGGKFMKSQGL

EIF4G2

421

P78344
AKVMMEVGQGKGFGV

PABPC5

331

Q96DU9
QKEAFHKQMMGGFKE

PACSIN2

116

Q9UNF0
GEGSYGMVMKCRNKD

CDKL2

11

Q92772
RMGCMKSKFLQVGGN

HCK

21

P08631
GMQMMNKVFGGTVHK

GMPS

106

P49915
MKNGGQETIEMMKGG

DSC3

771

Q14574
AFGIAMGKMGDQAKL

SLC1A2

251

P43004
MGKMGDQAKLMVDFF

SLC1A2

256

P43004
YGMGAKSLGEQMGIK

POLQ

2391

O75417
KHGMFLMAFENKAGL

GNA12

126

Q03113
NGMGDMGAKMLAKAL

CARMIL1

581

Q5VZK9
EGDMVAIGMKNGEFI

EML5

1746

Q05BV3
KMLGLKGNGGAVLSM

GTDC1

186

Q4AE62
IKMEVNGHGKAMALG

SALL3

1061

Q9BXA9
MDFVMKQALGGATKD

CPLX2

1

Q6PUV4
KQALGGATKDMGKML

CPLX2

6

Q6PUV4
SQKLMAKMGFREGEG

CMTR1

91

Q8N1G2
AAFMGMLKGDNLGKT

PTGR1

311

Q14914
IQAAMGFKIDDKGMA

SERPINE1

81

P05121
VGFAMLGMIKAAGKK

GUCY1A2

246

P33402
GAMDMAKGAVQGGLD

PLIN4

131

Q96Q06
FLMVLGKGSFGKVML

PRKCA

341

P17252
MEKMADALLFGNFGV

SEL1L2

146

Q5TEA6
GKYMAAINGEKMQIG

NEXMIF

1226

Q5QGS0
GGGAAFVMEHLKMKS

FN3K

81

Q9H479
MKIVGDLFGAGKMFL

MTR

716

Q99707
MGLGGGMDFDSKKAY

SIRT2

301

Q8IXJ6
AFMALDALADGGVKM

PYCR2

181

Q96C36
FQGLAEGTKGTMKMD

PRDM1

26

O75626
AKFLNVEAAMVFGMG

SPTLC3

216

Q9NUV7
GNLKGMLMQFAEIGR

SLC26A3

446

P40879
GIMGMFASKAAAKTQ

POLD3

191

Q15054
ASAAGNKAPGKGNMM

POLD3

221

Q15054
GKTIEFHMGGNMELK

SGCB

236

Q16585
KMGKGVSFKDVAGMH

SPG7

301

Q9UQ90
MTKEFIDGSLQMGGK

STYX

101

Q8WUJ0
PKLFNAALAMTGKMG

CNGB1

1106

Q14028
AALAMTGKMGGKGAK

CNGB1

1111

Q14028
KIMNCGGFGMEATLL

SLC17A6

386

Q9P2U8
DGKMMADYGIRKGNL

UBD

141

O15205
EGMQMVKLRGGSKGL

PLCH2

51

O75038
GAQYLMQAAGLGRMK

SLC12A2

866

P55011
GGMQMFKALGSDDLV

RORB

336

Q92753
AGYLMGLNSAEMLKG

MYH13

386

Q9UKX3
KGGMFAGQLTKVGMQ

ACP6

116

Q9NPH0
KGSNAEMAGMEVGKK

PREX2

621

Q70Z35
GKKQMGYMGEMEVQG

ZNF862

81

O60290
RQGKGDFFLGCMLMA

TLCD3B

151

Q71RH2
GFGGQKFMEDMMPKV

RPE

146

Q96AT9
MEILKEGSSGMDNKG

UHRF1BP1

791

Q6BDS2
TMFGMLLFAGGKQDD

TPCN2

231

Q8NHX9
AYIKMMGGKGLKQAT

GLDC

816

P23378