Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

HIVEP1 GATAD2A VRK3 NCKAP5L PRDM2 GPC4 USP7 IFT122 DOT1L MGME1

2.88e-073981021035016035
Pubmed

Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.

MAGED1 ERC1 TNRC6B ZNF318 MCM10 TTK ADD1 CEP350

6.11e-07242102834011540
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FNDC3B MAGED1 KDM5A ERC1 CAPN1 TNRC6B TTK ADD1 CEP55 CEP350 AHNAK2 RBM17

1.48e-067241021236232890
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

TNRC6B ADD1 JAK1 ANO6 USP7 RHPN2P1 PLEKHA2 MICAL3 AHNAK2

1.81e-06378102934315543
Pubmed

The DNA sequence and analysis of human chromosome 6.

ENPP1 UNC93A TBC1D22B GPRC6A ZNF318 RUNX2 NT5DC1 CENPQ ADGB MCM9 NR2E1

2.24e-066221021114574404
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

HIVEP1 KDM5A ERC1 TNRC6B ZNF318 PRDM2 GREB1L TET1 PLEKHA2

4.10e-06418102934709266
Pubmed

FGF2 stimulation of the pyrophosphate-generating enzyme, PC-1, in pre-osteoblast cells is mediated by RUNX2.

ENPP1 RUNX2

8.52e-062102219049325
Pubmed

Calpain cleavage regulates the protein stability of p73.

CAPN1 TP73

8.52e-062102215975558
Pubmed

Runx2 haploinsufficiency ameliorates the development of ossification of the posterior longitudinal ligament.

ENPP1 RUNX2

8.52e-062102222927960
Pubmed

Members of the pogo superfamily of DNA-mediated transposons in the human genome.

TIGD1 TIGD2

8.52e-06210228917322
Pubmed

Tiggers and DNA transposon fossils in the human genome.

TIGD1 TIGD2

8.52e-06210228643651
Pubmed

Runt-related transcription factor 2 attenuates the transcriptional activity as well as DNA damage-mediated induction of pro-apoptotic TAp73 to regulate chemosensitivity.

RUNX2 TP73

8.52e-062102225331851
Pubmed

Ectonucleotide pyrophosphatase/phosphodiesterase-1 (ENPP1) protein regulates osteoblast differentiation.

ENPP1 RUNX2

8.52e-062102221930712
Pubmed

P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism.

CAPN1 TP73

8.52e-062102221516125
Pubmed

FNDC3A is required for adhesion between spermatids and Sertoli cells.

FNDC3B FNDC3A

8.52e-062102216904100
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

HIVEP1 MAGED1 ERC1 DTNA ZNF318 NCKAP5L TTK USP7 DOT1L TP73

9.35e-065881021038580884
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MAGED1 TNRC6B TBC1D22B ZNF318 TTK CEP55 AHNAK2

1.31e-05263102734702444
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ERC1 CAPN1 TNRC6B ZNF318 TRIM3 CEP55 CEP350 ANO6 MTIF2 USP7 MAPK3

1.38e-057541021133060197
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

FNDC3B HIVEP1 KDM5A DTNA ACO1 WWP1 DACT1 USP1 MYBPC2

1.63e-05497102923414517
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

UNC13B ERC1 DTNA ADD1 NRXN1

1.88e-05110102527889896
Pubmed

Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function.

RUNX2 GLI2

2.55e-053102217442891
Pubmed

Long non-coding RNA tumor protein 73 antisense RNA 1 influences an interaction between lysine demethylase 5A and promoter of tumor protein 73 to enhance the malignancy of colorectal cancer.

KDM5A TP73

2.55e-053102235896939
Pubmed

Intermittent traction stretch promotes the osteoblastic differentiation of bone mesenchymal stem cells by the ERK1/2-activated Cbfa1 pathway.

RUNX2 MAPK3

2.55e-053102222827283
Pubmed

Lead induces dysregulation of iron regulatory protein 1 via the extracellular signal-regulated kinase pathway in human vascular endothelial cells.

ACO1 MAPK3

2.55e-053102222502979
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

MAGED1 KDM5A ERC1 TNRC6B ZNF318 TRIM3 ADD1 FRY GOLGA8M NRXN1 PLPPR4 MAPK3

2.61e-059631021228671696
Pubmed

RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1.

RUNX2 GLI2 MAPK3

2.69e-0520102332662771
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

UNC13B NCAPD3 CAPN1 TRAPPC8 CEP350 MICAL3 SPATA22 MAPK3 TP73 RBM17

2.86e-056701021022990118
Pubmed

TRIM11 activates the proteasome and promotes overall protein degradation by regulating USP14.

MAGED1 JAK1 USP7

4.16e-0523102329581427
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

HIVEP1 KDM5A ERC1 TBC1D22B NCKAP5L TTK CEP350 TET1 PLEKHA2 CRTC2 AHNAK2

4.62e-058611021136931259
Pubmed

Gene/protein expression of CAPN1/2-CAST system members is associated with ERK1/2 kinases activity as well as progression and clinical outcome in human laryngeal cancer.

CAPN1 MAPK3

5.09e-054102227456359
Pubmed

Inhibition of the ERK1/2-ubiquitous calpains pathway attenuates experimental pulmonary fibrosis in vivo and in vitro.

CAPN1 MAPK3

5.09e-054102232017927
Pubmed

The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling.

RUNX2 MAPK3

5.09e-054102220503384
Pubmed

TRIM27-USP7 complex promotes tumour progression via STAT3 activation in human hepatocellular carcinoma.

JAK1 USP7

5.09e-054102235753056
Pubmed

Regulation of adult bone mass by the zinc finger adapter protein Schnurri-3.

WWP1 RUNX2

5.09e-054102216728642
Pubmed

Extracellular signal-regulated kinase and glycogen synthase kinase 3β regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism.

CAPN1 MAPK3

5.09e-054102223408424
Pubmed

Spata4 promotes osteoblast differentiation through Erk-activated Runx2 pathway.

RUNX2 MAPK3

5.09e-054102221445983
Pubmed

Mechanical stress-mediated Runx2 activation is dependent on Ras/ERK1/2 MAPK signaling in osteoblasts.

RUNX2 MAPK3

5.09e-054102217265428
Pubmed

The Interaction of the Tumor Suppressor FAM46C with p62 and FNDC3 Proteins Integrates Protein and Secretory Homeostasis.

FNDC3B FNDC3A

5.09e-054102232966780
Pubmed

Interferon gamma activation of Raf-1 is Jak1-dependent and p21ras-independent.

JAK1 MAPK3

5.09e-05410229446616
Pubmed

A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation.

RUNX2 USP7

5.09e-054102232385263
Pubmed

ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.

UNC13B ERC1

5.09e-054102228264913
Pubmed

AC3-33, a novel secretory protein, inhibits Elk1 transcriptional activity via ERK pathway.

C3orf33 MAPK3

5.09e-054102220680465
Pubmed

Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length.

RUNX2 GOLGA8M MAPK3

5.37e-0525102324161523
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

GATAD2A RUNX2 ADD1 JAK1 NR2E1 USP7 MAPK3 TP73 RBM17

5.65e-05583102929844126
Pubmed

Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins.

TBC1D22B SCEL MCM10 CLVS1 C11orf52 CRTC2

6.22e-05230102629513927
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

HIVEP1 GATAD2A VRK3 KDM5A WRN MCM10 PRDM2 USP7 DOT1L

7.78e-05608102936089195
Pubmed

MDM2 facilitates adipocyte differentiation through CRTC-mediated activation of STAT3.

JAK1 CRTC2

8.47e-055102227362806
Pubmed

Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division.

CAPN1 MAPK3

8.47e-055102210825211
Pubmed

MICALs, a family of conserved flavoprotein oxidoreductases, function in plexin-mediated axonal repulsion.

MICALL2 MICAL3

8.47e-055102212110185
Pubmed

Activation of cyclin-dependent kinase 5 by calpains contributes to human immunodeficiency virus-induced neurotoxicity.

CAPN1 MAPK3

8.47e-055102217897354
Pubmed

Deubiquitination of Ci/Gli by Usp7/HAUSP Regulates Hedgehog Signaling.

GLI2 USP7

8.47e-055102226120032
Pubmed

Dorfin ubiquitylates mutant SOD1 and prevents mutant SOD1-mediated neurotoxicity.

RNF19A RUNX2

8.47e-055102212145308
Pubmed

Role of Hippo/YAP signaling in irradiation-induced glioma cell apoptosis.

RUNX2 TP73

8.47e-055102231496812
Pubmed

Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis.

RUNX2 GLI2

8.47e-055102221151991
Pubmed

Concomitant activation of the JAK/STAT3 and ERK1/2 signaling is involved in leptin-mediated proliferation of renal cell carcinoma Caki-2 cells.

JAK1 MAPK3

8.47e-055102218787400
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

ERC1 NCKAP5L TTK CEP55 CEP350 DOT1L

1.00e-04251102629778605
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

GATAD2A KDM5A ERC1 WWP1 TNRC6B ZNF318 SCEL NCKAP5L JAK1 MTIF2 USP7 TP73

1.07e-0411161021231753913
Pubmed

L-arginine stimulates fibroblast proliferation through the GPRC6A-ERK1/2 and PI3K/Akt pathway.

GPRC6A MAPK3

1.27e-046102224651445
Pubmed

Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection.

JAK1 USP1

1.27e-046102237289831
Pubmed

Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA.

USP7 USP1

1.27e-046102232510829
Pubmed

A protective role for FGF-23 in local defence against disrupted arterial wall integrity?

ENPP1 RUNX2

1.27e-046102223523568
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

FNDC3B NCAPD3 MAGED1 ENPP1 MTIF2 MICAL3 IFT122 GALNT6 CRTC2

1.29e-04650102938777146
Pubmed

Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.

UNC13B ERC1

1.77e-047102236398873
Pubmed

Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues.

RUNX2 ANO6

1.77e-047102222936354
Pubmed

BMP7 and SHH regulate Pax2 in mouse retinal astrocytes by relieving TLX repression.

GLI2 NR2E1

1.77e-047102219505455
Pubmed

Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice.

ENPP1 RUNX2

1.77e-047102231064775
Pubmed

Bapx1 regulates patterning in the middle ear: altered regulatory role in the transition from the proximal jaw during vertebrate evolution.

RUNX2 GSC

1.77e-047102214973294
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ERC1 TNRC6B ZNF318 ADD1 CEP55 TET1 USP7 DOT1L

2.19e-04549102838280479
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

MAGED1 TTK CEP55 CEP350

2.29e-04101102424613305
Pubmed

Nef and cell signaling transduction: a possible involvement in the pathogenesis of human immunodeficiency virus-associated dementia.

MAPK3 ALK

2.36e-048102219455469
Pubmed

Analysis of the C9orf72 gene in patients with amyotrophic lateral sclerosis in Spain and different populations worldwide.

RUNX2 ANO6

2.36e-048102222936364
Pubmed

Lysyl oxidase (lox) gene deficiency affects osteoblastic phenotype.

RUNX2 LOXL4

2.36e-048102219458888
Pubmed

The Penta-EF-Hand ALG-2 Protein Interacts with the Cytosolic Domain of the SOCE Regulator SARAF and Interferes with Ubiquitination.

WWP1 FNDC3A

2.36e-048102232878247
Pubmed

The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.

RUNX2 GSC TSC22D1 HOXD3 GLI2

2.57e-04191102524146773
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

DTNA WWP1 TBC1D22B MTMR10 ANO6 GRAMD2B MICAL3 C11orf52

2.79e-04569102830639242
Pubmed

EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.

JAK1 MAPK3 MMP12

2.97e-0444102335493520
Pubmed

The differential modulation of USP activity by internal regulatory domains, interactors and eight ubiquitin chain types.

USP7 USP1

3.03e-049102222195557
Pubmed

Impaired skin and hair follicle development in Runx2 deficient mice.

RUNX2 GLI2

3.03e-049102218262513
Pubmed

P90 Ribosomal s6 kinase 2 negatively regulates axon growth in motoneurons.

ERC1 MAPK3

3.03e-049102219555761
Pubmed

A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization.

ENPP1 RUNX2

3.03e-049102221788370
Pubmed

Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets.

RUNX2 GLI2

3.03e-049102229311969
Pubmed

Dental niche cells directly contribute to tooth reconstitution and morphogenesis.

ENPP1 RUNX2

3.03e-049102236476878
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

MAGED1 GATAD2A TNRC6B ZNF318 MCM10 USP7 AHNAK2

3.43e-04444102734795231
Pubmed

Identification of NPM-ALK interacting proteins by tandem mass spectrometry.

MTIF2 ALK MYBPC2

3.62e-0447102314968112
Pubmed

TGF-beta1 induces the different expressions of lysyl oxidases and matrix metalloproteinases in anterior cruciate ligament and medial collateral ligament fibroblasts after mechanical injury.

LOXL4 MMP12

3.77e-0410102223357697
Pubmed

p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice.

RUNX2 MAPK3

3.77e-0410102222585574
Pubmed

Activation of p38 MAPK pathway in the skull abnormalities of Apert syndrome Fgfr2(+P253R) mice.

RUNX2 MAPK3

3.77e-0410102220175913
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

LRRC66 MAGED1 WWP1 TNRC6B TBC1D22B ZNF318 MCM10 NCKAP5L GPC4 PLEKHA2

3.86e-049221021027609421
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ERC1 TNRC6B ADD1 CEP350 MICAL3

3.88e-04209102536779422
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

UNC13B MAGED1 KDM5A ERC1 ACO1 MTMR10 CEP350 JAK1 FRY MTIF2 USP7 IFT122

3.88e-0412851021235914814
Pubmed

The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen.

RUNX2 GLI2

4.60e-0411102210572046
Pubmed

Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.

GLI2 IFT122

4.60e-0411102233103996
Pubmed

Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.

RUNX2 GLI2

4.60e-0411102215668330
Pubmed

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.

GLI2 IFT122

4.60e-0411102222689656
Pubmed

Role of Indian hedgehog signaling in palatal osteogenesis.

RUNX2 GLI2

4.60e-0411102221364421
Pubmed

Ectopic Activation of Fgf8 in Dental Mesenchyme Causes Incisor Agenesis and Molar Microdontia.

RUNX2 MAPK3

4.60e-0411102239000154
Pubmed

Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification.

RUNX2 GLI2

4.60e-0411102222493482
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NCAPD3 HIVEP1 KDM5A ZNF318 ADD1 PRDM2 USP7 MICAL3 MAPK3

4.64e-04774102915302935
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

TNRC6B NCKAP5L CEP55 PLPPR4 MICALL2

4.70e-04218102533378226
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

WRN TNRC6B TBC1D22B ZNF318 MCM10 ADD1 CEP350 FRRS1 ANO6

4.77e-04777102935844135
GeneFamilyHelix-turn-helix CENPB type domain containing

TIGD1 TIGD2

7.98e-0413592533
GeneFamilyLIM domain containing

SCEL MICALL2 MICAL3

9.42e-04595931218
GeneFamilyC2 domain containing|Calpains

CAPN1 ADGB

1.07e-0315592975
GeneFamilyExonucleases

WRN MGME1

1.22e-0316592544
CoexpressionGSE17721_CTRL_VS_CPG_24H_BMDC_UP

GSC ADD1 JAK1 TMEM242 GRAMD2B ERCC6L2 IFT122 C11orf52

1.19e-062001028M3771
CoexpressionGSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP

UNC13B MAGED1 ENPP1 NCKAP5L GLI2 GALNT6 DOT1L

1.27e-051981027M9778
CoexpressionGSE17721_CTRL_VS_LPS_0.5H_BMDC_UP

ERC1 ADD1 JAK1 TMEM242 GRAMD2B IFT122 GALNT6

1.36e-052001027M3679
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RNF19A ERC1 FNDC3A GREB1L FRY HOXD3 PLEKHA2 SPATA22

1.02e-081851018a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 MCM10 TTK CEP55 ADGB TP73

2.87e-06174101684da9faff088d05233183b425385beb054c92d1b
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

ENPP1 RUNX2 GSC PLPPR4 GLI2 GPC4

3.27e-061781016e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MCM10 TTK CEP55 ADAMTS12 GLI2 TP73

4.34e-061871016e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MCM10 TTK CEP55 ADAMTS12 GLI2 TP73

4.34e-061871016cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CPA4 STEAP4 SCEL GRAMD2B LOXL4 AHNAK2

5.69e-0619610163e99a367b7d817e1f1221450fcec20ad7a7c7a2a
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CPA4 STEAP4 SCEL GRAMD2B LOXL4 AHNAK2

5.69e-0619610161efacc37bbfbd05b5d4db3dd10f6d9a238d23e31
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CPA4 STEAP4 SCEL GRAMD2B LOXL4 AHNAK2

5.86e-06197101608b371309cd790b171ed76cabc7d910e71cd2835
ToppCellBAL-Severe-Epithelial-Epithelial-transitional_Epi|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CPA4 STEAP4 SCEL GRAMD2B LOXL4 AHNAK2

5.86e-0619710169f49feee38647bbf964974aac96fa75602186b5c
ToppCellSmart-seq2-spleen_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RUNX2 TSC22D1 FRY TLDC2 GRAMD2B

2.21e-051481015f90ee6fbd71b5e0512af34867202f38409f4de38
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TSC22D1 NR2E1 PLD5 MAPK3 ALK

2.51e-051521015fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TSC22D1 NR2E1 PLD5 MAPK3 ALK

2.93e-051571015516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 MCM10 TTK CEP55 MGME1

3.62e-0516410151642a67c66eeb77a218e7814e3cfe517d9822955
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 MCM10 TTK CEP55 MGME1

3.62e-05164101525758fb8112baf296264122d5d4121f1ebb3d0fa
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GREB1L NR2E1 LOXL4 PLD5 ALK

4.17e-051691015f47c4fbdc2a38745ec1b35104b85121c1413875a
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 TTK CEP55 CENPQ USP1

4.79e-051741015c988471207ba06195bc3e41056435e8c31c20bbe
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 MCM10 TTK CENPQ USP1

4.79e-05174101566555c610251ea04f968c258e312d720c18e7cde
ToppCellClub-club-15|World / Class top

MCM10 CEP55 MMP12 USP1 MGME1

4.92e-051751015ca9d012f520f697c7450ec6958a015e20538a6a8
ToppCellRSV-Healthy-2|Healthy / Virus stimulation, Condition and Cluster

NCAPD3 WRN TTK MTIF2 TET1

4.92e-051751015c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCellRSV-Healthy-2|RSV / Virus stimulation, Condition and Cluster

NCAPD3 WRN TTK MTIF2 TET1

4.92e-0517510150e97189585b7afaf3bd622c3ef10c86412393829
ToppCellfacs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP1 FNDC3A GRAMD2B TP73 GABRA4

5.06e-0517610155f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

NCAPD3 MCM10 TTK CEP55 TP73

5.06e-051761015a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UNC13B DTNA TBC1D22B NRXN1 ALK

5.63e-051801015c72f15763ba707189e29c85db533557f01c7fdb1
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

UNC93A RUNX2 GREB1L FRY LOXL4

5.63e-05180101549829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 MCM10 TTK CEP55 TP73

5.63e-051801015401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WWP1 GREB1L NR2E1 PLD5 ALK

5.78e-05181101503a303cd2f366f09c18b118bbba6f5e3f95ad56c
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIGD1 TTK TET1 USP7 C11orf52

5.93e-051821015d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIGD1 TTK TET1 USP7 C11orf52

5.93e-05182101592f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TIGD1 TTK TET1 USP7 C11orf52

5.93e-05182101502baca9a72c7b559c3e452693b3b134af804c868
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF19 ENPP1 ACO1 MACROD1 GPC4

6.09e-051831015d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellfacs-Marrow-T-cells-3m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAGED1 ENPP1 HOXD3 TP73 GABRA4

6.09e-051831015b0b835f3b1de1bd46a47e1b805aa8994cd3a4e3e
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DTNA GPRC6A DACT1 NRXN1 GPC4

6.25e-0518410154cb5f299dd7413e0be1ad7af817ee614b23a18ae
ToppCellDividing_Macrophages-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

NCAPD3 MCM10 TTK CEP55 CENPQ

6.25e-051841015f15ce786d25c6546804a6d1efcc2ad645f2ef54e
ToppCelldroplet-Lung-1m-Mesenchymal-myofibroblast-pericyte_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DTNA GPRC6A DACT1 NRXN1 GPC4

6.25e-05184101539bb0eb55bdc2cea46e41c7f21d8c5883f14e6bd
ToppCelldroplet-Limb_Muscle-nan-24m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGEF19 ADGB NRXN1 C11orf91 IFT122

6.57e-051861015adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MACROD1 GREB1L NR2E1 PLD5 ALK

6.74e-051871015d2ffb2f34f07b0dd5d3cb3ee0275f46ebecf4146
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 MTMR10 GREB1L FRY SPATA22

6.74e-051871015e3095455d2f255854f339f6b05fa87852af0700f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MACROD1 GREB1L NR2E1 PLD5 ALK

6.91e-051881015ee572246e0c2f41bdbc29a03edc67b831af95c09
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ERC1 MTMR10 GREB1L FRY SPATA22

7.09e-0518910153a295c215b5c18e7c673f92b7af5be523421682c
ToppCellNS-critical-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NCAPD3 ENPP1 MCM10 TTK CEP55

7.09e-051891015d6bd46abb072b13a6b72f1ca25d19f218cceb1ff
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 MCM10 TTK CEP55 USP1

7.27e-051901015c3c65d1f24e0ebdbb9adb617bed299a668f423f5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENPP1 STEAP4 ADAMTS12 GLI2 PLD5

7.45e-051911015a6c57627077fa980b7ec1d3894b5f31bfb11b738
ToppCellEndothelial-Endothelial-D_(cycle)|Endothelial / shred on cell class and cell subclass (v4)

NCAPD3 TTK CEP55 CENPQ USP1

7.45e-051911015a3c5a913a99f17633c140ec9ece81b73e59e0715
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MCM10 TTK CEP55 CENPQ USP1

7.45e-051911015b978afe76754cc56e1672abca27be289bb56375b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENPP1 STEAP4 ADAMTS12 GLI2 PLD5

7.45e-0519110158f6d592edc32fdb901af30501d4360512334e8c2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B GATAD2A DTNA FNDC3A DOT1L

7.64e-0519210158b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellP07-Endothelial-proliferative_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NCAPD3 TTK CEP55 CENPQ USP1

7.82e-0519310151e95ef29357969ee385b4717c0b5a497390ac260
ToppCellP07-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NCAPD3 TTK CEP55 CENPQ USP1

7.82e-0519310150f21fb8b35f89f4c1c8109d1a4d3d08a452f9edd
ToppCellP03-Endothelial-proliferative_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NCAPD3 TTK CEP55 CENPQ USP1

8.02e-05194101522bcfb0f3f73608feb22c0847ab4d34f87aeede0
ToppCellP03-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NCAPD3 TTK CEP55 CENPQ USP1

8.02e-0519410155e56ce9b9fe0721be3a9e6efe1422599bb867721
ToppCell(1)_T_cells_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

NCAPD3 MCM10 TTK CEP55 USP1

8.02e-0519410158f313071933451780309d2174ed27d8cdc734343
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NCAPD3 MCM10 TTK CEP55 USP1

8.02e-0519410154c1d13d8cb6fb424655c67755ee6dbaf59d6b418
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 MCM10 TTK CEP55 CENPQ

8.02e-0519410153a49c7c86036e09a8cd0114988380d04ad1a26fb
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasmablasts|lymph-node_spleen / Manually curated celltypes from each tissue

FNDC3B MCM10 TTK CEP55 TP73

8.21e-0519510151390728b9a514db534e8bc6dcf72cf51a1065780
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MCM10 TTK CEP55 USP1 MGME1

8.21e-051951015926eb3fc5d028be936885bea0654a77db3107234
ToppCelldroplet-Tongue-TONGUE-1m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCAPD3 TTK CEP55 CENPQ USP1

8.21e-051951015b57132802cb977551e214880984f3edcd375474f
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 TTK CEP55 CENPQ USP1

8.41e-05196101520383d576708b7e4bfce3e9fe40548cce496e3cb
ToppCellCOVID-19-lung-Proliferative_fibroblast|lung / Disease (COVID-19 only), tissue and cell type

MCM10 TTK CEP55 ADAMTS12 GLI2

8.41e-0519610152ce8a787f2731faa913d20342d73041d59468f27
ToppCellCOVID-19-lung-Proliferative_fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

MCM10 TTK CEP55 ADAMTS12 GLI2

8.41e-051961015ca91d5e325875e7444809b80fcbd491d8899ea36
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NCAPD3 TTK CEP55 CENPQ USP1

8.41e-0519610150644bd14a944b9c9759a295dfdd5e67a4775f20a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCAPD3 MCM10 RUNX2 CEP55 USP1

8.41e-051961015de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENPP1 RUNX2 ADAMTS12 MICALL2 GLI2

8.62e-051971015ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellproximal-Hematologic-Proliferating_Macrophage|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPD3 MCM10 TTK CEP55 CENPQ

8.62e-0519710150b1fa881abbfcc54b322fc27124db3f8947af016
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ENPP1 RUNX2 ADAMTS12 MICALL2 GLI2

8.62e-05197101537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGED1 ENPP1 TSC22D1 FRY LOXL4

8.62e-0519710154b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCellSevere_COVID-19-Epithelial-transitional_Epi|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

STEAP4 SCEL GRAMD2B LOXL4 AHNAK2

8.62e-0519710155ad3cd4c77016e862041baac3076f8cc0f75c417
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MAGED1 ENPP1 TSC22D1 FRY LOXL4

8.62e-051971015ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCellproximal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPD3 MCM10 TTK CEP55 CENPQ

8.62e-0519710150dd9058aa19d1268ebba9a65555870224b5a5978
ToppCellproximal-Hematologic-Proliferating_Macrophage-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NCAPD3 MCM10 TTK CEP55 CENPQ

8.62e-0519710159243617b307acf3df40d93c41cd8d4788699a7ea
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSC22D1 FRY NRXN1 PLPPR4 GABRA4

8.83e-0519810156d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TSC22D1 FRY NRXN1 PLPPR4 GABRA4

8.83e-0519810154ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

NCAPD3 MCM10 TTK CEP55 USP1

8.83e-0519810156a10bb81817ab606f1f5a2bd8cfe77ef2fb3f2fb
ToppCellnormal_Lung-T/NK_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

NCAPD3 MCM10 TTK CEP55 USP1

8.83e-051981015c65cdb54409087014125a76627e5efb5fe8dabc9
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NCAPD3 TTK CEP55 NR2E1 MGME1

8.83e-05198101550f236ab7ef6f00721f6cd714e3eee183077beeb
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW19-Stem_cells|GW19 / Sample Type, Dataset, Time_group, and Cell type.

NCAPD3 TTK CEP55 NR2E1 MGME1

8.83e-051981015dc0c6189ff9dd76675f63acf1cbc7dda60e75f3f
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-051991015e98ff036d04fc78dffef156bdc0d644532274067
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-051991015305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-0519910157feedb0bf84a3361c8ab5b6674ff64e8ff140c23
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-051991015123fbf2122aa221d8cbf3aef9361ba0982c07695
ToppCellCOVID-19_Severe-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Severe / Disease group, lineage and cell class

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-051991015ddae7fe7633661f15d3c79f5187415ffbfecce67
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-051991015fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MCM10 TTK CEP55 TP73 MGME1

9.04e-0519910151d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NCAPD3 MCM10 TTK CEP55 USP1

9.04e-0519910156b1304417cf9c44ca70d2bfc2b5acc1a206f25b6
ToppCellmild_COVID-19-T/NK_proliferative|mild_COVID-19 / disease group, cell group and cell class (v2)

NCAPD3 MCM10 TTK CEP55 CENPQ

9.04e-051991015df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

NCAPD3 MCM10 TTK CEP55 USP1

9.25e-0520010154cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells-Neuroepithelial_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

MCM10 TTK CEP55 CENPQ USP1

9.25e-0520010152938a029fa0478be561574ace91f95c4a528b2d4
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MCM10 TTK CEP55 USP1 TP73

9.25e-05200101514c9ced92763858f3d35186cd3908bd0f4cfd872
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12|Neuronal / cells hierarchy compared to all cells using T-Statistic

MACROD1 GREB1L NR2E1 PLD5 ALK

9.25e-052001015c74bc12e13d002dedaaf75a2244ec111e47524e1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells-Neuroepithelial_cell|2m / Sample Type, Dataset, Time_group, and Cell type.

MCM10 TTK CEP55 NR2E1 USP1

9.25e-0520010150d9b8d51a7630e70e60c76c763ff82df4c559152
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-PAX6-CDH12-L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

MACROD1 GREB1L NR2E1 PLD5 ALK

9.25e-052001015ead9eb579bb25fde05fc15602e3d05ab6617f7ac
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Severe / Disease, condition lineage and cell class

NCAPD3 MCM10 TTK CEP55 USP1

9.25e-0520010150892603e604c2a945dd720685d45970f855bd5d3
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Stem_cells|2m / Sample Type, Dataset, Time_group, and Cell type.

MCM10 TTK CEP55 NR2E1 USP1

9.25e-0520010150675f580ccef705875854247bbfd4ee2bcf126a1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Stem_cells|3m / Sample Type, Dataset, Time_group, and Cell type.

MCM10 TTK CEP55 CENPQ USP1

9.25e-052001015cfe017b4a4d604a553d0a3df9659687f38e9a7af
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

MCM10 CENPQ NR2E1 GPC4 MGME1

9.25e-052001015c00cc0b91baa37828895d9d6b8acbc6aa503215a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells|GW09 / Sample Type, Dataset, Time_group, and Cell type.

MCM10 CENPQ NR2E1 GPC4 MGME1

9.25e-0520010159e1b62a703fb7d413ce580448a1df5127c28e8a7
ToppCellsevere-T/NK_proliferative|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NCAPD3 MCM10 TTK CEP55 USP1

9.25e-052001015d341f4e500377a5bef82c24bf64704b981053336
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NCAPD3 MCM10 TTK CENPQ MGME1

9.25e-05200101543571c9284d4e41402a2d1eefc1efe2ce8476d4a
ToppCellSepsis-URO-Lymphocyte-T/NK-T/NK_proliferative|URO / Disease, condition lineage and cell class

NCAPD3 MCM10 TTK CEP55 TP73

9.25e-052001015f277db6cc288a52a5426120c1067608700ee8ccc
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MCM10 TTK CEP55 TP73 MGME1

9.25e-05200101563f9481059be608ddc9fe9c7a8f8503fce9755dd
ToppCellCOVID_vent-Lymphocytic-Proliferative_Lymphocyte-|COVID_vent / Disease condition, Lineage, Cell class and subclass

NCAPD3 MCM10 TTK CEP55 USP1

9.25e-0520010157e4c0db43a03ca11380a54f44a3cf1991e055b80
DiseaseTNF-related apoptosis-inducing ligand measurement

FNDC3B DTNA TRAPPC8 FOLH1B

9.90e-0572984EFO_0008300
DiseaseHuntington disease, disease progression measurement

MTMR10 ADD1 ADGB

1.35e-0430983EFO_0008336, MONDO_0007739
Diseasesocial interaction measurement

HIVEP1 TNRC6B NRXN1 USP1

2.77e-0494984EFO_0009592
Diseasenon-alcoholic fatty liver disease

ARHGEF19 GATAD2A PLPPR4 MICAL3 USP1

3.61e-04182985EFO_0003095
Diseasediastolic blood pressure, systolic blood pressure

UNC13B FNDC3B GATAD2A TNRC6B ADD1 CEP350 OR1I1 FOLH1B LOXL4

3.97e-04670989EFO_0006335, EFO_0006336
Diseasediabetic maculopathy

USP7 ALK

7.05e-0412982EFO_0010133
Diseasecartilage thickness measurement

RUNX2 DOT1L

1.61e-0318982EFO_0007873
Diseaseankylosing spondylitis (is_implicated_in)

KDM5A ANO6

1.80e-0319982DOID:7147 (is_implicated_in)
DiseaseCraniofacial Abnormalities

RUNX2 GSC NRXN1 GPC4

1.85e-03156984C0376634
DiseaseCraniosynostosis

RUNX2 IFT122

2.00e-0320982C0010278
Diseaseunipolar depression, memory performance, cognitive function measurement

TRAPPC8 TET1

2.00e-0320982EFO_0003761, EFO_0004874, EFO_0008354
Diseasedyslexia

CPA4 GATAD2A NRXN1 MOV10L1

2.12e-03162984EFO_0005424
Diseaseotitis media (implicated_via_orthology)

ENPP1 TP73

2.42e-0322982DOID:10754 (implicated_via_orthology)
Diseasebeta-aminoisobutyric acid measurement

KDM5A NT5DC1

2.87e-0324982EFO_0010464

Protein segments in the cluster

PeptideGeneStartEntry
LATPSDKLFFWNSKS

ACO1

626

P21399
AASKRKTWQPLSKST

CENPQ

66

Q7L2Z9
LLTAETFSWKSLKPG

ADGB

711

Q8N7X0
TFSWKSLKPGSLVLK

ADGB

716

Q8N7X0
KSKWGSKPSNSKSET

CEP55

11

Q53EZ4
WKSTFSPISDIGLAK

DOT1L

1241

Q8TEK3
NSSKTYGIKWKRPTE

CAPN1

76

P07384
KTLSSFCKWQKSINP

ADAMTS12

316

P58397
SSMNSIKTFWSPELK

ERC1

181

Q8IUD2
LTTPWKFKVAKQLAS

JAK1

686

P23458
WSNVTPLKFSKINTG

MMP12

141

P39900
DKQWLFSKLPEVKST

ARHGEF19

416

Q8IW93
PFWKLNITCESSKKL

ANO6

356

Q4KMQ2
KGSATSNWKKTPLST

GATAD2A

576

Q86YP4
PKSRLKSLTNKNSFW

LOXL4

231

Q96JB6
EAAAKPKSLWKSVFS

MICAL3

1731

Q7RTP6
KPLNTSSKKWGSFFI

NT5DC1

366

Q5TFE4
FGLWSPEQKSVSKHK

IFT122

116

Q9HBG6
AREPFSWKKLKSSQA

MOV10L1

456

Q9BXT6
RPKTPFKAWNDTTKA

MAGED1

176

Q9Y5V3
SIASWFGLKKSKLPA

NCKAP5L

916

Q9HCH0
GPWKSQLSSTKSKKV

MTIF2

76

P46199
DWKTSEKPKPFIQST

MGME1

251

Q9BQP7
PLSKFLSGAKIWLST

MTMR10

756

Q9NXD2
EKLKQAKKFWSSLPS

GPC4

391

O75487
SKFRLSKIWSPKSKS

MICALL2

886

Q8IY33
EGKSLYESWTKKSPS

FOLH1B

181

Q9HBA9
KVWTPDTFFRNGKKS

GABRA4

126

P48169
KLKSLKDSCSWAGPT

GLI2

736

P10070
ASFSLKSKEKFNPEW

ENPP1

286

P22413
SKTKVAWAKLFPKSD

MAPK3

286

P27361
PQSVNSGKTFSIWKL

MCM10

306

Q7L590
SSSATISKQIFPWMK

HOXD3

151

P31249
TPESFISLPKWNAKK

NRXN1

486

Q9ULB1
ISLPKWNAKKTGSIS

NRXN1

491

Q9ULB1
FKIPSTRGKWKAFST

OR1I1

226

O60431
KWSSKLTSQSLKAPF

GREB1L

1671

Q9C091
LPKSSSQKKGSSWQA

KDM5A

1191

P29375
SDTPKGLWKLKSLQS

LRRC66

161

Q68CR7
SGKSATWQKSKDLQA

GPRC6A

886

Q5T6X5
TAKSATWTYSPLLKK

TP73

136

O15350
GTFSPPKQWSKESKA

DACT1

411

Q9NYF0
LLKPWDAKKLSSSSS

CRTC2

226

Q53ET0
SKKTEIKVYWNAPSS

FRRS1

121

Q6ZNA5
DGKAFQKSKWTPLET

GALNT6

116

Q8NCL4
SLTLQWKAPSDNGSK

FNDC3A

386

Q9Y2H6
PQSLKLKWGDSNSKT

FNDC3B

971

Q53EP0
SNNLKLNFWKSPSSF

CPA4

46

Q9UI42
SWVNAPISKSTKSRK

CEP350

86

Q5VT06
IWKKDSFLKTTGSDF

C3orf33

236

Q6P1S2
TSTDWKEAKSFLKGL

MACROD1

91

Q9BQ69
SWKSPAKKLTNALSK

DTNA

291

Q9Y4J8
KWNKTSSSKASPEKR

GSC

231

P56915
WTSASKELPGKTLDF

FRY

2316

Q5TBA9
SNEKFLWKKFSPSDT

ERCC6L2

1536

Q5T890
QKKIISLWSKSSFDG

GRAMD2B

61

Q96HH9
SIKWAKSVPAFSTLS

NR2E1

196

Q9Y466
AAWTDAGLTSKKSKL

PRDM2

761

Q13029
LENKGYPSKSEKLWS

MCM9

506

Q9NXL9
LWPSTLSKKSQAGAS

RUNX2

351

Q13950
KKALCKAPSVASSWQ

PLEKHA2

341

Q9HB19
SKQFWKRSAKLPGSI

TBC1D22B

6

Q9NU19
SSLKFKSRVPQTWSK

PLD5

271

Q8N7P1
KNTSLKTWNKNDFKP

SPATA22

116

Q8NHS9
NQLSSPSKAGTEWKL

GOLGA8M

196

H3BSY2
GKKKHTESTPFWSIK

SPESP1

111

Q6UW49
RLPVWFAKGSDTSKK

WRN

1406

Q14191
KLDSSSEPFKKGRWT

TSC22D1

411

Q15714
KTLWKALAEKPASSG

MROH2B

1101

Q7Z745
GKISSSTKIWKPLAQ

TET1

1211

Q8NFU7
TYGSWFTEKPTKKNN

ALK

1506

Q9UM73
PKLSTSGFEWSSKKV

AHNAK2

4631

Q8IVF2
QNGSSPKSKTKWTKE

ADD1

461

P35611
IWSKKEKFSPTFINN

NCAPD3

691

P42695
WSCPSTFQKKKKTGS

C11orf52

11

Q96A22
ISSSPLSDFNIWKKL

C11orf91

31

Q3C1V1
WSNFSFKQASKLTPS

CLVS1

186

Q8IUQ0
TSPKSSSARAKWLKA

PLPPR4

546

Q7Z2D5
VKSSTITKAWKKLFP

TIGD2

376

Q4W5G0
SGLPEGKSSATKWSK

RNF19A

651

Q9NV58
TKSTLPVLYKWNSKA

TIGD1

251

Q96MW7
TWKFKVSKIPGTFKQ

TAS2R9

166

Q9NYW1
SATTPVKKKRQSWFP

SCEL

151

O95171
TSDSKTEGWSKNFKL

RBM17

11

Q96I25
KKSVPFWSTLLSTFK

UNC93A

236

Q86WB7
KAVDLSWSALKAPKS

TTC41P

61

Q6P2S7
LKKENPFSTSSAWLS

STEAP4

331

Q687X5
RKFTTKSKSNNWAPK

UNC13B

1476

O14795
GLNSSFETSPKKVKW

VRK3

51

Q8IV63
ISKKLSFLSWGTNKN

RHPN2P1

531

A8MT19
KSKSKISPKSDVWSL

TTK

706

P33981
FSATKKWFSGSKVPE

TRAPPC8

386

Q9Y2L5
KWFSGSKVPEKSIND

TRAPPC8

391

Q9Y2L5
FSPQLKVFKWTGSNS

TLDC2

141

A0PJX2
TKTAKSSSSSNPKWD

WWP1

51

Q9H0M0
FITTLSLAKKKSPEW

TMEM242

46

Q9NWH2
SLAKKKSPEWFNKGS

TMEM242

51

Q9NWH2
TKKLTKSFGWETLDS

USP7

276

Q93009
ESPTSSSFGKFSWKK

ZNF318

1266

Q5VUA4
SSKWKSSLSKRALGN

HIVEP1

2016

P15822
WLKSATKQPSILSKF

USP1

341

O94782
LGVWKSDPKAKSVQS

TNRC6B

256

Q9UPQ9
WVSIFSPEGKFKTKI

TRIM3

556

O75382
PTASGAKWTQKKGSS

ZAN

226

Q9Y493
NQLSSPSKAGTEWKL

GOLGA8IP

196

A6NC78
TLKWFKNGQEIKPSS

MYBPC2

286

Q14324