Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	modification-dependent protein binding	NANOGP8 NANOG PSMD4 CHD8 BPTF BRD4 ZFAND6 KMT2A TAF1 HDGFL2 CBX2	2.28e-08	206	112	11	GO:0140030
GeneOntologyMolecularFunction	histone binding	SART3 NANOGP8 NANOG MCM2 CHD8 INO80 BPTF BRD4 KMT2A TAF1 HDGFL2 CBX2	3.17e-08	265	112	12	GO:0042393
GeneOntologyMolecularFunction	lysine-acetylated histone binding	NANOGP8 NANOG BRD4 KMT2A TAF1	6.47e-07	30	112	5	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	NANOGP8 NANOG BRD4 KMT2A TAF1	7.67e-07	31	112	5	GO:0140033
GeneOntologyMolecularFunction	methylated histone binding	CHD8 BPTF TAF1 HDGFL2 CBX2	1.23e-04	86	112	5	GO:0035064
GeneOntologyMolecularFunction	methylation-dependent protein binding	CHD8 BPTF TAF1 HDGFL2 CBX2	1.37e-04	88	112	5	GO:0140034
GeneOntologyMolecularFunction	RNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity	NANOGP8 NANOG	1.86e-04	4	112	2	GO:0001010
GeneOntologyMolecularFunction	ErbB-2 class receptor binding	ERBIN MUC4	1.86e-04	4	112	2	GO:0005176
GeneOntologyMolecularFunction	potassium channel regulator activity	FXYD5 AMIGO1 KCNE4 WNK3	2.95e-04	57	112	4	GO:0015459
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 HDGFL2	3.08e-04	5	112	2	GO:0061628
GeneOntologyMolecularFunction	protein kinase activity	RIOK1 LRRK1 TEX14 BRD4 PRKAB2 ALPK3 AKT2 TAF1 PEAK1 MAPK8 WNK3	5.56e-04	600	112	11	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	RIOK1 LRRK1 TEX14 BRD4 PRKAB2 ALPK3 AKT2 TAF1 PEAK1 PIPSL MAPK8 WNK3	6.30e-04	709	112	12	GO:0016773
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	MCM2 MCM3 CHD8 INO80 BPTF	7.49e-04	127	112	5	GO:0008094
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	RIOK1 LRRK1 BRD4 PRKAB2 ALPK3 AKT2 TAF1 MAPK8 WNK3	9.22e-04	446	112	9	GO:0004674
GeneOntologyMolecularFunction	kinase activity	RIOK1 LRRK1 TEX14 BRD4 PRKAB2 ALPK3 AKT2 TAF1 PEAK1 PIPSL MAPK8 WNK3	1.20e-03	764	112	12	GO:0016301
GeneOntologyMolecularFunction	potassium channel inhibitor activity	KCNE4 WNK3	1.66e-03	11	112	2	GO:0019870
GeneOntologyCellularComponent	GATOR1 complex	NPRL3 DEPDC5	2.82e-04	5	112	2	GO:1990130
GeneOntologyCellularComponent	methyltransferase complex	RIOK1 CHD8 KMT2A BOD1L1 TAF1	2.90e-04	108	112	5	GO:0034708
GeneOntologyCellularComponent	transferase complex	ZSWIM8 RIOK1 MCM3 ATG14 CHD8 IRS1 CHM BRD4 PRKAB2 KMT2A BOD1L1 DEPDC5 TAF1 CBX2	6.34e-04	963	112	14	GO:1990234
GeneOntologyCellularComponent	MLL1 complex	CHD8 KMT2A TAF1	6.63e-04	32	112	3	GO:0071339
GeneOntologyCellularComponent	histone methyltransferase complex	CHD8 KMT2A BOD1L1 TAF1	7.08e-04	75	112	4	GO:0035097
GeneOntologyCellularComponent	MLL1/2 complex	CHD8 KMT2A TAF1	7.27e-04	33	112	3	GO:0044665
HumanPheno	Hyperextensibility at elbow	KMT2A CAMTA1 SON	7.55e-06	6	38	3	HP:0010485
HumanPheno	Focal cortical dysplasia type IIa	NPRL3 DEPDC5	5.42e-05	2	38	2	HP:0032052
HumanPheno	Synophrys	LEMD3 KIF26A BPTF ASXL3 BRD4 KMT2A TAF1 RAI1	7.26e-05	195	38	8	HP:0000664
HumanPheno	Facial hypertrichosis	LEMD3 KIF26A BPTF ASXL3 BRD4 KMT2A TAF1 RAI1	1.07e-04	206	38	8	HP:0002219
HumanPheno	Deeply set eye	LEMD3 CASZ1 EDEM3 BPTF ASXL3 TAF1 CAMTA1 RAI1 SON	1.08e-04	266	38	9	HP:0000490
HumanPheno	Thick eyebrow	LEMD3 BPTF ASXL3 BRD4 KMT2A DEPDC5 TAF1	1.16e-04	154	38	7	HP:0000574
HumanPheno	Broad lateral eyebrow	KMT2A SON	1.62e-04	3	38	2	HP:0007933
HumanPheno	Increased intraabdominal fat	LIPE AKT2	1.62e-04	3	38	2	HP:0008993
HumanPheno	Abnormal location of ears	RPGRIP1 KIF26A ZNF423 SLC5A7 CHD8 CASZ1 EDEM3 CDCA7 ASXL3 BRD4 KMT2A DEPDC5 TAF1 CAMTA1 WNK3 RAI1 SON	1.79e-04	945	38	17	HP:0000357
HumanPheno	Obesity	PCARE CHD8 CASZ1 CEP164 BPTF LIPE BRD4 SYNE2 AKT2 TAF1 RAI1	1.81e-04	425	38	11	HP:0001513
HumanPheno	Abnormal eyebrow morphology	LEMD3 KIF26A ZNF423 CHD8 KANK2 CASZ1 BPTF ASXL3 BRD4 KMT2A DEPDC5 TAF1 RAI1 SON	1.98e-04	674	38	14	HP:0000534
HumanPheno	Auditory hallucination	NPRL3 DEPDC5 SON	2.01e-04	16	38	3	HP:0008765
HumanPheno	Medial flaring of the eyebrow	LEMD3 KIF26A BPTF ASXL3 BRD4 KMT2A TAF1 RAI1	2.17e-04	228	38	8	HP:0010747
HumanPheno	Long eyelashes	ASXL3 BRD4 KMT2A DEPDC5 TAF1 CAMTA1	3.33e-04	129	38	6	HP:0000527
Domain	BROMODOMAIN_2	BPTF BRD4 KMT2A TAF1	9.41e-05	41	109	4	PS50014
Domain	BROMO	BPTF BRD4 KMT2A TAF1	1.04e-04	42	109	4	SM00297
Domain	Bromodomain	BPTF BRD4 KMT2A TAF1	1.04e-04	42	109	4	IPR001487
Domain	-	BPTF BRD4 KMT2A TAF1	1.04e-04	42	109	4	1.20.920.10
Domain	ZF_PHD_2	BPTF ASXL3 KMT2A PHF21B RAI1	2.36e-04	95	109	5	PS50016
Domain	ZF_PHD_1	BPTF ASXL3 KMT2A PHF21B RAI1	2.47e-04	96	109	5	PS01359
Domain	RETICULON	RTN4 RTN3	3.34e-04	5	109	2	PS50845
Domain	Bromodomain_CS	BPTF BRD4 TAF1	4.56e-04	26	109	3	IPR018359
Domain	MCM_N	MCM2 MCM3	4.99e-04	6	109	2	IPR027925
Domain	MCM_N	MCM2 MCM3	4.99e-04	6	109	2	PF14551
Domain	MCM_CS	MCM2 MCM3	4.99e-04	6	109	2	IPR018525
Domain	AT_hook	KMT2A BOD1L1 CBX2	5.11e-04	27	109	3	SM00384
Domain	AT_hook_DNA-bd_motif	KMT2A BOD1L1 CBX2	5.11e-04	27	109	3	IPR017956
Domain	Reticulon	RTN4 RTN3	6.95e-04	7	109	2	PF02453
Domain	MCM_OB	MCM2 MCM3	9.24e-04	8	109	2	IPR033762
Domain	MCM_2	MCM2 MCM3	9.24e-04	8	109	2	PS50051
Domain	MCM_1	MCM2 MCM3	9.24e-04	8	109	2	PS00847
Domain	Reticulon	RTN4 RTN3	9.24e-04	8	109	2	IPR003388
Domain	MCM_OB	MCM2 MCM3	9.24e-04	8	109	2	PF17207
Domain	MAGE	MAGEA10 MAGEC3 MAGEC1	1.01e-03	34	109	3	SM01373
Domain	MCM	MCM2 MCM3	1.18e-03	9	109	2	SM00350
Domain	MCM_dom	MCM2 MCM3	1.18e-03	9	109	2	IPR001208
Domain	MCM	MCM2 MCM3	1.18e-03	9	109	2	IPR031327
Domain	MCM	MCM2 MCM3	1.18e-03	9	109	2	PF00493
Domain	DUF3699	TASOR2 GARIN3	1.18e-03	9	109	2	PF12480
Domain	DUF3699	TASOR2 GARIN3	1.18e-03	9	109	2	IPR022168
Domain	MAGE	MAGEA10 MAGEC3 MAGEC1	1.20e-03	36	109	3	PS50838
Domain	MAGE	MAGEA10 MAGEC3 MAGEC1	1.20e-03	36	109	3	PF01454
Domain	MHD_dom	MAGEA10 MAGEC3 MAGEC1	1.20e-03	36	109	3	IPR002190
Domain	BROMODOMAIN_1	BPTF BRD4 TAF1	1.30e-03	37	109	3	PS00633
Domain	Bromodomain	BPTF BRD4 TAF1	1.41e-03	38	109	3	PF00439
Domain	PDZ	DLG5 IL16 FRMPD4 ERBIN PDZD2	1.42e-03	141	109	5	PF00595
Domain	HAT	SART3 ZFC3H1	1.47e-03	10	109	2	IPR003107
Domain	HAT	SART3 ZFC3H1	1.47e-03	10	109	2	SM00386
Domain	PDZ	DLG5 IL16 FRMPD4 ERBIN PDZD2	1.76e-03	148	109	5	SM00228
Domain	PHD	BPTF KMT2A PHF21B RAI1	1.83e-03	89	109	4	SM00249
Domain	-	DLG5 IL16 FRMPD4 ERBIN PDZD2	1.87e-03	150	109	5	2.30.42.10
Domain	PDZ	DLG5 IL16 FRMPD4 ERBIN PDZD2	1.92e-03	151	109	5	PS50106
Domain	PDZ	DLG5 IL16 FRMPD4 ERBIN PDZD2	1.98e-03	152	109	5	IPR001478
Domain	Znf_PHD	BPTF KMT2A PHF21B RAI1	1.99e-03	91	109	4	IPR001965
Domain	-	SART3 LEMD3 SAFB SYNJ2 RBM47 HNRNPLL	3.09e-03	244	109	6	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	SART3 LEMD3 SAFB SYNJ2 RBM47 HNRNPLL	4.06e-03	258	109	6	IPR012677
Pubmed	NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler.	CHD8 BPTF BRD4 BOD1L1	5.86e-10	5	116	4	26626481
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DLG5 IRS1 EDC4 RAB11FIP1 ERBIN NHSL1 SYNJ2 BRD4 SYNE2 KMT2A BOD1L1 MPHOSPH9 PROSER2 PEAK1 KIF13A WNK3 CCSER1	4.37e-09	861	116	17	36931259
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SART3 LEMD3 MCM3 CHD8 TASOR2 BPTF SAFB BRD4 KMT2A BOD1L1 TAF1 HDGFL2 RAI1 SON CBX2 HDLBP	1.22e-07	954	116	16	36373674
Pubmed	BRD4 regulates Nanog expression in mouse embryonic stem cells and preimplantation embryos.	NANOGP8 NANOG BRD4	1.44e-07	4	116	3	25146928
Pubmed	RNA-binding protein Rbm47 binds to Nanog in mouse embryonic stem cells.	NANOGP8 NANOG RBM47	1.44e-07	4	116	3	23649762
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	MCM3 CHD8 EDC4 PHAX ERBIN BPTF BRD4 KMT2A BOD1L1 TAF1 PEAK1 HDLBP	3.30e-07	549	116	12	38280479
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SART3 PSMD4 CHD8 PHAX BPTF BRD4 BOD1L1 TAF1 HDGFL2	4.91e-07	283	116	9	30585729
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	DLG5 ITSN1 PSMD4 CHD8 PHAX KANK2 ERBIN BPTF SAFB LLGL1 HDGFL2	5.60e-07	472	116	11	38943005
Pubmed	Nogo-66 regulates nanog expression through stat3 pathway in murine embryonic stem cells.	NANOGP8 NANOG RTN4	7.18e-07	6	116	3	19400741
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CHD8 INO80 PHAX CASZ1 BPTF BRD4 KMT2A BOD1L1 TAF1 HDGFL2 RAI1 CBX2	9.65e-07	608	116	12	36089195
Pubmed	Tip110 Deletion Impaired Embryonic and Stem Cell Development Involving Downregulation of Stem Cell Factors Nanog, Oct4, and Sox2.	SART3 NANOGP8 NANOG	1.25e-06	7	116	3	28436127
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	SART3 MCM2 MCM3 CHD8 INO80 PHAX BPTF SAFB BRD4 KMT2A BOD1L1 TAF1 HNRNPLL HDGFL2 SON	1.49e-06	1014	116	15	32416067
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SART3 DLG5 KIF26A RTN4 MCM2 CHD8 LRRK1 INO80 SYNJ2 DEPDC5 RAI1	1.70e-06	529	116	11	14621295
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	MCM3 CHD8 EDC4 BPTF SAFB BOD1L1 TAF1 HNRNPLL HDLBP	1.84e-06	332	116	9	32786267
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ITSN1 MCM2 MCM3 ERBIN BPTF SAFB USP42 BRD4 KMT2A PROSER2 MAPK8 SON HDLBP	1.99e-06	774	116	13	15302935
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	MCM2 CHD8 TASOR2 BPTF USP42 BRD4 KMT2A BOD1L1 MUC4 HDGFL2	4.12e-06	469	116	10	27634302
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KIF26A CHD8 FYCO1 IRS1 LRRK1 INO80 EDC4 CASZ1 NHSL1 BRD4 NPRL3 AKT2 DEPDC5 RAI1 CBX2	4.25e-06	1105	116	15	35748872
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BPTF SAFB BRD4 KMT2A TAF1	5.42e-06	75	116	5	25593309
Pubmed	A human MAP kinase interactome.	KIF26A ITSN1 PSMD4 CHD8 ERBIN SYNJ2 MPHOSPH9 TAF1 RNF111 HDLBP	5.64e-06	486	116	10	20936779
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SART3 MCM2 CHD8 INO80 EDC4 BRD4 KMT2A TAF1 RAI1	7.36e-06	394	116	9	27248496
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	LEMD3 NANOG MUC16 MCM2 INO80 BPTF GARIN3 USP42 CBX2	7.66e-06	396	116	9	26687479
Pubmed	A mouse-specific retrotransposon drives a conserved Cdk2ap1 isoform essential for development.	NANOGP8 NANOG MPHOSPH9	7.78e-06	12	116	3	34644528
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	MCM3 PSMD4 SAFB BRD4 BOD1L1 PROSER2 HDGFL2 SON HDLBP	8.14e-06	399	116	9	35987950
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SART3 DLG5 LEMD3 ITSN1 RTN4 RTN3 LRRC40 ZFC3H1 RAB11FIP1 KANK2 ERBIN LLGL1 SYNE2 AKT2 PEAK1 HDGFL2 HDLBP	9.05e-06	1487	116	17	33957083
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SART3 DLG5 LEMD3 CHD8 INO80 ZFC3H1 EDC4 RAB11FIP1 KANK2 ERBIN CASZ1 CEP164 KMT2A HNRNPLL HDGFL2 SON HDLBP	9.87e-06	1497	116	17	31527615
Pubmed	BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos.	NANOGP8 NANOG BRD4	1.01e-05	13	116	3	35264162
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	ZSWIM8 ZNF423 CHD8 TASOR2 BPTF SAFB BRD4 KMT2A SON	1.03e-05	411	116	9	35182466
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	TASOR2 BPTF KMT2A CBX2 HDLBP	1.06e-05	86	116	5	37253089
Pubmed	GATOR1-related focal cortical dysplasia in epilepsy surgery patients and their families: A possible gradient in severity?	NPRL3 DEPDC5	1.10e-05	2	116	2	33461085
Pubmed	Pro-apoptotic ASY/Nogo-B protein associates with ASYIP.	RTN4 RTN3	1.10e-05	2	116	2	12811824
Pubmed	Functional evidence that the self-renewal gene NANOG regulates human tumor development.	NANOGP8 NANOG	1.10e-05	2	116	2	19415763
Pubmed	Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation.	RTN4 RTN3	1.10e-05	2	116	2	18779370
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	1.10e-05	2	116	2	23544943
Pubmed	Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication.	RTN4 RTN3	1.10e-05	2	116	2	37093123
Pubmed	The Implication of Reticulons (RTNs) in Neurodegenerative Diseases: From Molecular Mechanisms to Potential Diagnostic and Therapeutic Approaches.	RTN4 RTN3	1.10e-05	2	116	2	33924890
Pubmed	RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles.	RTN4 RTN3	1.10e-05	2	116	2	37318453
Pubmed	Ino80 promotes cervical cancer tumorigenesis by activating Nanog expression.	NANOG INO80	1.10e-05	2	116	2	27750218
Pubmed	Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.	NANOGP8 NANOG	1.10e-05	2	116	2	24598770
Pubmed	Differential expression of nanog1 and nanogp8 in colon cancer cells.	NANOGP8 NANOG	1.10e-05	2	116	2	22079639
Pubmed	Diagnostic exome sequencing in non-acquired focal epilepsies highlights a major role of GATOR1 complex genes.	NPRL3 DEPDC5	1.10e-05	2	116	2	32086284
Pubmed	Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.	NANOGP8 NANOG	1.10e-05	2	116	2	21136380
Pubmed	RTN3 and RTN4: Candidate modulators in vascular cell apoptosis and atherosclerosis.	RTN4 RTN3	1.10e-05	2	116	2	20717916
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	DLG5 RIOK1 LEMD3 ZC3HC1 EDC4 KANK2 ERBIN KMT2A MPHOSPH9 RAI1 CBX2	1.11e-05	645	116	11	25281560
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	EFCAB6 LEMD3 MUC16 ZC3HC1 MAGEC3 MCM3 ERBIN TASOR2 LIPE MPHOSPH9 PEAK1 HNRNPLL	1.17e-05	777	116	12	35844135
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART3 ZSWIM8 CHD8 EDC4 TASOR2 BPTF SYNE2 KMT2A RAI1 SON HDLBP	1.24e-05	653	116	11	22586326
Pubmed	Ino80 is essential for proximal-distal axis asymmetry in part by regulating Bmp4 expression.	NANOGP8 NANOG INO80	1.28e-05	14	116	3	26975355
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SART3 RIOK1 RTN4 PSMD4 EDC4 PHAX ERBIN SAFB KMT2A BOD1L1 HDGFL2 SON HDLBP	1.50e-05	934	116	13	33916271
Pubmed	Integrated Proteomics-Based Physical and Functional Mapping of AXL Kinase Signaling Pathways and Inhibitors Define Its Role in Cell Migration.	RTN4 KANK2 ERBIN LLGL1	1.72e-05	46	116	4	35022314
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	MCM2 MCM3 ZFC3H1 SAFB HDGFL2 HDLBP	1.87e-05	163	116	6	22113938
Pubmed	Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.	NIBAN1 LEMD3 RTN4 RAB11FIP1 KANK2 ERBIN SSH3 PEAK1	1.91e-05	339	116	8	37232246
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	ITSN1 RTN4 ZC3HC1 MCM2 PSMD4 CDCA7 MAPK8	1.97e-05	246	116	7	15345747
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	DLG5 RTN4 KANK2 ERBIN NHSL1 LLGL1 SYNJ2 SSH3 PEAK1 HDLBP	2.07e-05	565	116	10	25468996
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SART3 IL16 ITSN1 RTN4 RTN3 ZC3HC1 EDC4 KANK2 ERBIN NHSL1 SAFB SLC24A2 PTPRZ1 KMT2A PEAK1 HDLBP	2.23e-05	1431	116	16	37142655
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	SART3 RPGRIP1 PCDHGA7 ITSN1 ZFC3H1 TEX14 ERBIN TASOR2 BPTF RIMKLB SAFB SYNE2 KMT2A BOD1L1 HDGFL2 RAI1	2.45e-05	1442	116	16	35575683
Pubmed	Interaction network of human early embryonic transcription factors.	ZNF423 CHD8 INO80 BPTF ASXL3 KMT2A TAF1 RAI1	2.45e-05	351	116	8	38297188
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	DLG5 RIOK1 RTN4 MCM3 LRRC40 ERBIN LLGL1 BOD1L1 MPHOSPH9 PEAK1 HDLBP	2.62e-05	708	116	11	39231216
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	SART3 FRMPD4 RTN4 RTN3 PSMD4 EDC4 ERBIN NHSL1 SAFB PITPNM3 AKT2 PEAK1 HNRNPLL HDLBP	2.74e-05	1139	116	14	36417873
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	DLG5 ITSN1 MCM2 MCM3 PSMD4 LRRC40 EDC4 SYNE2	3.11e-05	363	116	8	25036637
Pubmed	The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.	NANOGP8 NANOG	3.30e-05	3	116	2	30814124
Pubmed	Multiple phases in regulation of Nanog expression during pre-implantation development.	NANOGP8 NANOG	3.30e-05	3	116	2	26660234
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	3.30e-05	3	116	2	23053434
Pubmed	Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.	NANOGP8 NANOG	3.30e-05	3	116	2	18177668
Pubmed	Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.	NANOGP8 NANOG	3.30e-05	3	116	2	24929238
Pubmed	Nanog and transcriptional networks in embryonic stem cell pluripotency.	NANOGP8 NANOG	3.30e-05	3	116	2	17211451
Pubmed	Cryo-EM structures of the human GATOR1-Rag-Ragulator complex reveal a spatial-constraint regulated GAP mechanism.	NPRL3 DEPDC5	3.30e-05	3	116	2	35338845
Pubmed	The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.	NANOGP8 NANOG	3.30e-05	3	116	2	15502159
Pubmed	Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.	NANOGP8 NANOG	3.30e-05	3	116	2	20574542
Pubmed	lincRNAs act in the circuitry controlling pluripotency and differentiation.	NANOGP8 NANOG	3.30e-05	3	116	2	21874018
Pubmed	Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.	NANOGP8 NANOG	3.30e-05	3	116	2	23054952
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	3.30e-05	3	116	2	30236127
Pubmed	CrxOS maintains the self-renewal capacity of murine embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	19800316
Pubmed	SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes.	KMT2A SON	3.30e-05	3	116	2	26990989
Pubmed	Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.	NANOGP8 NANOG	3.30e-05	3	116	2	26975336
Pubmed	Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.	NANOGP8 NANOG	3.30e-05	3	116	2	23329853
Pubmed	Unlike Its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival.	KMT2A HDGFL2	3.30e-05	3	116	2	33477970
Pubmed	Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.	NANOGP8 NANOG	3.30e-05	3	116	2	23665121
Pubmed	Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.	NANOGP8 NANOG	3.30e-05	3	116	2	26733157
Pubmed	Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.	NANOGP8 NANOG	3.30e-05	3	116	2	16501172
Pubmed	Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	19582141
Pubmed	Nanog is the gateway to the pluripotent ground state.	NANOGP8 NANOG	3.30e-05	3	116	2	19703398
Pubmed	Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.	NANOGP8 NANOG	3.30e-05	3	116	2	28636920
Pubmed	A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.	NANOGP8 NANOG	3.30e-05	3	116	2	20539761
Pubmed	Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.	NANOGP8 NANOG	3.30e-05	3	116	2	18584034
Pubmed	Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	21969378
Pubmed	The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells.	NANOGP8 NANOG	3.30e-05	3	116	2	20661723
Pubmed	NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.	NANOGP8 NANOG	3.30e-05	3	116	2	29245050
Pubmed	Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.	NANOGP8 NANOG	3.30e-05	3	116	2	15494369
Pubmed	Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog.	NANOGP8 NANOG	3.30e-05	3	116	2	14728807
Pubmed	Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.	NANOGP8 NANOG	3.30e-05	3	116	2	21194951
Pubmed	Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.	NANOGP8 NANOG	3.30e-05	3	116	2	22388986
Pubmed	Nanog promotes transfer of pluripotency after cell fusion.	NANOGP8 NANOG	3.30e-05	3	116	2	16791199
Pubmed	Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	18024963
Pubmed	The pluripotency factor Nanog regulates pericentromeric heterochromatin organization in mouse embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	27125671
Pubmed	Stochastic promoter activation affects Nanog expression variability in mouse embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	25410303
Pubmed	Cell fate determinant Llgl1 is required for propagation of acute myeloid leukemia.	LLGL1 KMT2A	3.30e-05	3	116	2	37587260
Pubmed	Genome editing demonstrates that the -5 kb Nanog enhancer regulates Nanog expression by modulating RNAPII initiation and/or recruitment.	NANOGP8 NANOG	3.30e-05	3	116	2	33334884
Pubmed	Forced expression of Nanog in hematopoietic stem cells results in a gammadeltaT-cell disorder.	NANOGP8 NANOG	3.30e-05	3	116	2	17360937
Pubmed	The two-hydrophobic domain tertiary structure of reticulon proteins is critical for modulation of beta-secretase BACE1.	RTN4 RTN3	3.30e-05	3	116	2	19405102
Pubmed	Nanog dynamics in single embryonic stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	26760119
Pubmed	Nanog is dispensable for the generation of induced pluripotent stem cells.	NANOGP8 NANOG	3.30e-05	3	116	2	24461999
Interaction	CSNK2A1 interactions	SART3 IL16 RIOK1 NANOG HLX MCM2 MCM3 IRS1 ZFC3H1 ANKRD36C KANK2 SAFB ASXL3 BRD4 KMT2A TAF1 HDGFL2 RNF111 CBX2 HDLBP	2.82e-07	956	112	20	int:CSNK2A1
Interaction	ARRDC2 interactions	SART3 ZSWIM8 PSMD4 LLGL1 BOD1L1 PIPSL	5.35e-07	54	112	6	int:ARRDC2
Interaction	MUC16 interactions	NANOG MUC16 MCM2 FYCO1	2.03e-06	17	112	4	int:MUC16
Interaction	TAF6 interactions	MCM3 PSMD4 PHAX CHM SAFB BRD4 KMT2A BOD1L1 TAF1	9.27e-06	245	112	9	int:TAF6
Interaction	YWHAG interactions	DLG5 RTN3 MCM2 MCM3 IRS1 EDC4 RAB11FIP1 ERBIN NHSL1 CDCA7 SYNJ2 SYNE2 KMT2A BOD1L1 MPHOSPH9 PROSER2 PEAK1 KIF13A SON CCSER1	1.63e-05	1248	112	20	int:YWHAG
Interaction	H3-3A interactions	RIOK1 NANOG MCM2 CHD8 INO80 PHAX CASZ1 BPTF BRD4 KMT2A BOD1L1 TAF1 HDGFL2 RAI1 CBX2	1.71e-05	749	112	15	int:H3-3A
Interaction	H3C14 interactions	RIOK1 NANOG MCM2 BRD4 KMT2A HDGFL2 CBX2	2.67e-05	156	112	7	int:H3C14
Interaction	SSRP1 interactions	NANOG MCM2 MCM3 ZFC3H1 PHAX CEP164 SAFB BRD4 KMT2A HDGFL2 RAI1 SON CBX2 HDLBP	2.67e-05	685	112	14	int:SSRP1
Interaction	SASS6 interactions	DLG5 NANOG ZC3HC1 FYCO1 CEP164 MPHOSPH9 TNFRSF1B	3.02e-05	159	112	7	int:SASS6
Interaction	GFPT1 interactions	ZNF423 MCM2 PSMD4 BRD4 PRKAB2 MAPK8 HDLBP	3.14e-05	160	112	7	int:GFPT1
Interaction	YWHAH interactions	DLG5 MCM2 IRS1 EDC4 RAB11FIP1 ERBIN NHSL1 CDCA7 SYNJ2 BRD4 SYNE2 KMT2A BOD1L1 MPHOSPH9 PROSER2 PEAK1 WNK3 CCSER1	3.57e-05	1102	112	18	int:YWHAH
Interaction	BAG2 interactions	NANOG MCM2 LRRC40 LRRK1 ZFC3H1 EDC4 ERBIN BPTF LLGL1 BRD4 BOD1L1 WNK3 HDLBP	4.20e-05	622	112	13	int:BAG2
Interaction	BUB3 interactions	RIOK1 MCM2 ZFC3H1 ASXL3 BRD4 KMT2A BOD1L1 HDLBP	4.65e-05	232	112	8	int:BUB3
Interaction	CADPS interactions	FOXD2 FYCO1 ZFC3H1 KANK2 OLIG3	5.75e-05	74	112	5	int:CADPS
Interaction	MCM10 interactions	SHLD2 MCM2 MCM3 ATG14 TNFRSF1B PIPSL	6.75e-05	124	112	6	int:MCM10
Interaction	ASF1A interactions	MCM2 CHD8 CASZ1 TASOR2 KMT2A TAF1 RAI1 CBX2	7.64e-05	249	112	8	int:ASF1A
Interaction	LHX3 interactions	INO80 TEX14 KANK2 SYNE2 PRKAB2 TAF1 TSKS	7.89e-05	185	112	7	int:LHX3
Interaction	RAB35 interactions	DLG5 RIOK1 LEMD3 ITSN1 RTN3 RAB11FIP1 CHM ERBIN LLGL1 SYNE2 AKT2 PEAK1	8.28e-05	573	112	12	int:RAB35
Interaction	H2BC3 interactions	RIOK1 MCM2 PSMD4 CHD8 EDC4 BRD4 KMT2A AKT2 RAI1 CBX2	8.98e-05	406	112	10	int:H2BC3
Interaction	KCNA3 interactions	DLG5 IL16 RIOK1 RTN4 MCM3 LRRC40 FYCO1 ERBIN KCNE4 LLGL1 KMT2A BOD1L1 MPHOSPH9 PEAK1 HDLBP	9.54e-05	871	112	15	int:KCNA3
Interaction	H3C3 interactions	RIOK1 MCM2 CHD8 BPTF BRD4 KMT2A BOD1L1 TAF1 HDGFL2 RAI1 CBX2	9.88e-05	495	112	11	int:H3C3
Interaction	POU5F1 interactions	LEMD3 NANOG RTN4 MUC16 LRRC40 INO80 BPTF GARIN3 USP42 BRD4 TAF1 CBX2	9.91e-05	584	112	12	int:POU5F1
Interaction	GATA4 interactions	ZSWIM8 ZNF423 CHD8 TASOR2 BPTF SAFB BRD4 KMT2A SON HDLBP	9.93e-05	411	112	10	int:GATA4
Interaction	SUMO2 interactions	RIOK1 MCM3 CHD8 EDC4 BPTF SAFB BRD4 BOD1L1 TAF1 HNRNPLL RNF111 HDLBP	1.11e-04	591	112	12	int:SUMO2
Interaction	SFN interactions	MCM2 IRS1 TEX14 EDC4 RAB11FIP1 ERBIN CDCA7 SYNJ2 KMT2A MPHOSPH9 PEAK1 KIF13A CCSER1	1.23e-04	692	112	13	int:SFN
Interaction	UHRF2 interactions	CHD8 TASOR2 BPTF BRD4 KMT2A CBX2 HDLBP	1.28e-04	200	112	7	int:UHRF2
Interaction	SMC5 interactions	SART3 LEMD3 MCM3 CHD8 TASOR2 BPTF SAFB BRD4 KMT2A BOD1L1 TAF1 HDGFL2 RAI1 SON CBX2 HDLBP	1.29e-04	1000	112	16	int:SMC5
Interaction	H3C15 interactions	RIOK1 NANOG MCM2 PHAX SYNJ2 BRD4 KMT2A	1.59e-04	207	112	7	int:H3C15
Interaction	TOP3B interactions	RIOK1 KIF26A CHD8 FYCO1 IRS1 LRRK1 INO80 EDC4 KANK2 CASZ1 NHSL1 SAFB BRD4 NPRL3 AKT2 DEPDC5 RBM47 RAI1 CBX2 HDLBP	1.60e-04	1470	112	20	int:TOP3B
Interaction	MEN1 interactions	SART3 NANOG ZC3HC1 MCM2 CHD8 INO80 ZFC3H1 EDC4 ERBIN ZFY BPTF SAFB KMT2A BOD1L1 TAF1 SON	1.79e-04	1029	112	16	int:MEN1
Interaction	RTF1 interactions	MCM2 PSMD4 BRD4 KMT2A HDGFL2 CBX2	1.92e-04	150	112	6	int:RTF1
Interaction	SMARCAL1 interactions	LLGL1 BRD4 PIPSL HDLBP	2.15e-04	53	112	4	int:SMARCAL1
Interaction	APEX1 interactions	SART3 ZSWIM8 ITSN1 INO80 CASZ1 BPTF RIMKLB SAFB CDCA7 SSH3 BRD4 KMT2A MPHOSPH9 KIF13A HNRNPLL HDGFL2 RAI1 CBX2	2.18e-04	1271	112	18	int:APEX1
Interaction	GJD3 interactions	DLG5 LEMD3 ITSN1 RTN4 RTN3 PSMD4 ERBIN LLGL1 SYNE2 PEAK1	2.23e-04	454	112	10	int:GJD3
Interaction	TERF2IP interactions	MCM2 PSMD4 CHD8 TASOR2 BPTF BRD4 KMT2A BOD1L1 TAF1 RAI1 CBX2	2.55e-04	552	112	11	int:TERF2IP
GeneFamily	CD molecules\|Mucins	MUC16 MUC22 MUC4	8.30e-05	21	74	3	648
GeneFamily	PDZ domain containing	DLG5 IL16 FRMPD4 ERBIN PDZD2	3.97e-04	152	74	5	1220
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RPGRIP1 ITSN1 RAB11FIP1	4.26e-04	36	74	3	823
GeneFamily	MAGE family	MAGEA10 MAGEC3 MAGEC1	5.83e-04	40	74	3	1136
GeneFamily	MCM family	MCM2 MCM3	5.84e-04	9	74	2	1085
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	ZC3HC1 ZFC3H1	1.68e-03	15	74	2	26
GeneFamily	NKL subclass homeoboxes and pseudogenes	NANOGP8 NANOG HLX	2.61e-03	67	74	3	519
GeneFamily	PHD finger proteins	BPTF KMT2A PHF21B	5.99e-03	90	74	3	88
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_2500_k-means-cluster#4	ZNF423 RTN3 BPTF LLGL1 USP42 PTPRZ1 SYNE2 BOD1L1 DEPDC5 TAF1 HNRNPLL WNK3 PHF21B SON	3.39e-06	595	113	14	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_2500_K4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	KIF26A ZNF423 SLC5A7 KANK2 RIMKLB PTPRZ1 ASXL3 BRD4 ARHGAP28 GRIN3A MAPK8 KIF13A SON HDLBP CCSER1	2.89e-05	818	113	15	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DLG5 MUC16 ANKRD36C RAB11FIP1 CASZ1 MUC4 RAI1	4.54e-07	179	116	7	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	(08)_Brush+PNEC-(2)_GFP_FOXI1\|(08)_Brush+PNEC / shred by cell type by condition	ITSN1 BPTF BRD4 SYNE2 BOD1L1 MUC4	1.68e-06	138	116	6	817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF26A LRRC40 LRRK1 ANKRD36C PITPNM3 CBX2	6.20e-06	173	116	6	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	KIF26A LRRC40 LRRK1 ANKRD36C PITPNM3 CBX2	6.20e-06	173	116	6	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NIBAN1 MUC16 RIMKLB LLGL1 KIF13A MUC4	6.40e-06	174	116	6	42f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLG5 CFAP100 SSC5D RIMKLB PTPRZ1 ALPK3	8.81e-06	184	116	6	6b0c110d8930df99043c3b99cf4d873985126960
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLG5 CFAP100 SSC5D RIMKLB PTPRZ1 ALPK3	8.81e-06	184	116	6	35928fc5f7bbf8c7b09181a2bd27e22dff42ec16
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	ANKRD36C BPTF BRD4 KMT2A BOD1L1 SON	1.12e-05	192	116	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 ANKRD36C PTPRZ1 DEPDC5 MUC4 WNK3	1.34e-05	198	116	6	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	RTN4 ANKRD36C BPTF KMT2A MAPK8 CCSER1	1.34e-05	198	116	6	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	RTN3 IRS1 BPTF BRD4 SYNE2 BOD1L1	1.38e-05	199	116	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	DLG5 MUC16 ANKRD36C SYNJ2 PTPRZ1 CCSER1	1.41e-05	200	116	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Nasal_Brush-Epithelial\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	MUC16 ANKRD36C SYNE2 RBM47 MUC4 HDLBP	1.41e-05	200	116	6	7911073119ee47a37b68b73fc54f063e902a5067
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ZFC3H1 BPTF SYNE2 KMT2A BOD1L1 SON	1.41e-05	200	116	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DLG5 MUC16 CASZ1 PTPRZ1 SYNE2 MUC4	1.41e-05	200	116	6	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NIBAN1 MUC16 CASZ1 SYNJ2 RBM47 CCSER1	1.41e-05	200	116	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	facs-BAT-Fat-3m-Myeloid-myeloid_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG FXYD5 RAB11FIP1 TNFRSF1B RBM47	7.21e-05	165	116	5	bfe330751d34813af7540765b490406078c40da7
ToppCell	facs-BAT-Fat-3m-Myeloid\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG FXYD5 RAB11FIP1 TNFRSF1B RBM47	7.21e-05	165	116	5	8bdeacbb47948fabae2575689f811a9fad47f779
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MCM2 MCM3 TEX14 RIMKLB TSKS	7.42e-05	166	116	5	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HLX MCM2 LLGL1 SSH3 BOD1L1	7.63e-05	167	116	5	a54b8e03987a7b067173121902e1811a3d003692
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HLX MCM2 MCM3 CASZ1 CDCA7	9.77e-05	176	116	5	269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCell	facs-Skin-nan-18m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG EFCAB6 FXYD5 GARIN3 TNFRSF1B	1.00e-04	177	116	5	17065d37fd41f04f67282bee00365daa185e8355
ToppCell	facs-Skin-nan-18m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG EFCAB6 FXYD5 GARIN3 TNFRSF1B	1.00e-04	177	116	5	6e45e1a5a894ca2e4ebc5cdb17fdf79e9e188185
ToppCell	facs-Skin-nan-18m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG EFCAB6 FXYD5 GARIN3 TNFRSF1B	1.00e-04	177	116	5	9ff3a77c5c62c8a950c46ca22cd7bde425b84c9a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1_PAX6_CA4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FXYD5 KCNE4 CDCA7 ARHGAP28 GRIN3A	1.09e-04	180	116	5	392bc71a69653ba12de31bed4e9357f181094641
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FXYD5 KCNE4 CDCA7 ARHGAP28 GRIN3A	1.11e-04	181	116	5	8fd64404e57c22c204d835fc5626f73554257b19
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Epitheliod\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	RTN3 RAB11FIP1 SSH3 RBM47 PDZD2	1.14e-04	182	116	5	bb1f815718397de96682697fcbd6014a992a28f7
ToppCell	Control-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	NIBAN1 ANKRD36C SYNJ2 PTPRZ1 MUC4	1.17e-04	183	116	5	bdd461349a1ef43a015843937d26e8d3571ecc22
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLG5 SSC5D RIMKLB PTPRZ1 AKT2	1.20e-04	184	116	5	f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLG5 ITSN1 IRS1 KANK2 SSC5D	1.23e-04	185	116	5	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SHLD2 BOD1L1 PEAK1 RBM47 HNRNPLL	1.27e-04	186	116	5	bbb8edea8d8bdc1a469faec1563e40b1f62d7f3d
ToppCell	droplet-Skin-nan-21m-Lymphocytic-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG IL16 FXYD5 GARIN3 TNFRSF1B	1.30e-04	187	116	5	38d7b19fde6811f5fbf548b2464486b197476dc6
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EFCAB6 RIMKLB SYNE2 AKT2 PDZD2	1.30e-04	187	116	5	c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell	droplet-Skin-nan-21m-Lymphocytic\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG IL16 FXYD5 GARIN3 TNFRSF1B	1.30e-04	187	116	5	ea33a5bd60b7f5f6d5b07a7f06a5a56395943641
ToppCell	droplet-Skin-nan-21m-Lymphocytic-T_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELPLG IL16 FXYD5 GARIN3 TNFRSF1B	1.30e-04	187	116	5	1dbc2c0ab85033e5de776bbfdb73ebd3a50d2cc6
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NIBAN1 GLB1L MUC16 LLGL1 KIF13A	1.30e-04	187	116	5	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	COVID-19-Epithelial_cells\|COVID-19 / group, cell type (main and fine annotations)	RAB11FIP1 CASZ1 MUC4 PDZD2 CCSER1	1.33e-04	188	116	5	c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCell	droplet-Marrow-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HLX MCM2 MCM3 CDCA7 HNRNPLL	1.33e-04	188	116	5	1526e271411e381eae7a342003002276f83f47a3
ToppCell	normal_Pleural_Fluid-T/NK_cells-Treg\|normal_Pleural_Fluid / Location, Cell class and cell subclass	SELPLG NIBAN1 FXYD5 SYNE2 TNFRSF1B	1.40e-04	190	116	5	632b9541371483d25948b6f033863c49f38e3603
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 ANKRD36C MUC4 HDLBP CCSER1	1.40e-04	190	116	5	23f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell	normal-na-Lymphocytic_T-T4_reg-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NIBAN1 FXYD5 CDCA7 SYNE2 HNRNPLL	1.40e-04	190	116	5	d8c1998eb02d5105598608d4733b63978ffa3eb2
ToppCell	10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell\|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SELPLG FXYD5 SYNE2 TNFRSF1B HNRNPLL	1.40e-04	190	116	5	b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCell	normal-na-Lymphocytic_T-T4_reg\|normal / PBMC cell types (v2) per disease, treatment status, and sex	NIBAN1 FXYD5 CDCA7 SYNE2 HNRNPLL	1.40e-04	190	116	5	b8897c3e0fe8bb7efaf6a3787104d454d81a4c92
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 ANKRD36C MUC4 HDLBP CCSER1	1.40e-04	190	116	5	3c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tregs\|lymph-node_spleen / Manually curated celltypes from each tissue	SELPLG FXYD5 SYNE2 TNFRSF1B HNRNPLL	1.47e-04	192	116	5	04bd6e135733570e877af9460f87379ed0a5c5f8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 RAB11FIP1 MAPK8 RBM47 CCSER1	1.47e-04	192	116	5	2510f22197502f60fd266b7f42eff040f25b8ae7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RTN4 RAB11FIP1 MAPK8 RBM47 CCSER1	1.47e-04	192	116	5	e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IL16 FRMPD4 FXYD5 SYNE2 SON	1.50e-04	193	116	5	7deb439943d35a4e825674b2b7dcddb45d366ad1
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-Tregs\|blood / Manually curated celltypes from each tissue	SELPLG NIBAN1 FXYD5 CDCA7 SYNE2	1.50e-04	193	116	5	2ffe44edf2b02d11a7c10513692eb697a10f911e
ToppCell	Club_cells\|World / lung cells shred on cell class, cell subclass, sample id	MUC16 ANKRD36C PTPRZ1 SYNE2 MUC4	1.50e-04	193	116	5	9d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL16 RAB11FIP1 AKT2 BOD1L1 CCSER1	1.54e-04	194	116	5	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	Goblet_1\|World / shred by cell class for nasal brushing	MUC16 ANKRD36C RAB11FIP1 RBM47 MUC4	1.58e-04	195	116	5	d9e4889a2e7b7c97c07c15b043b77837739462e4
ToppCell	COPD-Lymphoid-T\|COPD / Disease state, Lineage and Cell class	NIBAN1 FYCO1 SYNJ2 SYNE2 HNRNPLL	1.62e-04	196	116	5	30e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCell	15-Trachea\|15 / Age, Tissue, Lineage and Cell class	MUC16 RAB11FIP1 CFAP100 RBM47 MUC4	1.62e-04	196	116	5	fd17403422cf95c24f6be1c2d78764bb352f7f2e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Teffector/EM_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	SELPLG NIBAN1 FXYD5 SYNE2 HNRNPLL	1.66e-04	197	116	5	c4603bfe9ab537ca64172f65203a5d23671f7354
ToppCell	Control-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	RTN4 RAB11FIP1 ERBIN TNFRSF1B SON	1.66e-04	197	116	5	eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	MUC16 ANKRD36C SYNJ2 PTPRZ1 MUC4	1.66e-04	197	116	5	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Reg_T\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NIBAN1 FXYD5 RAB11FIP1 TNFRSF1B HNRNPLL	1.69e-04	198	116	5	03423d6c614440b9c738f75ac3f5a6941719a279
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NHSL1 PEAK1 KIF13A PDZD2 CCSER1	1.69e-04	198	116	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	BPTF BRD4 SYNE2 BOD1L1 HDLBP	1.69e-04	198	116	5	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	Severe-CD4+_T_Exhausted\|World / Disease group and Cell class	FXYD5 RAB11FIP1 TNFRSF1B HNRNPLL HDLBP	1.73e-04	199	116	5	467c34893dd7d1a8a1c101c966f034cc04b9bcbd
ToppCell	Severe-CD4+_T_Exhausted\|Severe / Disease group and Cell class	FXYD5 RAB11FIP1 TNFRSF1B HNRNPLL HDLBP	1.73e-04	199	116	5	dc6b0291714e2b9501c0796a63678bfb9d1b1052
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	BPTF SYNJ2 BRD4 SYNE2 BOD1L1	1.73e-04	199	116	5	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	ITSN1 BPTF BRD4 SYNE2 BOD1L1	1.73e-04	199	116	5	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	IRS1 BPTF BRD4 SYNE2 BOD1L1	1.73e-04	199	116	5	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	ITSN1 BPTF BRD4 SYNE2 BOD1L1	1.73e-04	199	116	5	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	Bronchial_Biopsy-Epithelial\|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X	MUC16 PTPRZ1 SYNE2 RBM47 MUC4	1.73e-04	199	116	5	ef5d8917c8d011184830a0b8197afc6266707b37
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DLG5 CASZ1 PTPRZ1 SYNE2 MUC4	1.78e-04	200	116	5	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 CASZ1 EDEM3 RBM47 CCSER1	1.78e-04	200	116	5	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	FXYD5 RTN3 EDEM3 BPTF SON	1.78e-04	200	116	5	e3c15e0e1c2602b0cc9ab8cc50c978d265350c94
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITSN1 IRS1 KANK2 SSC5D KCNE4	1.78e-04	200	116	5	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MUC16 ANKRD36C RAB11FIP1 CASZ1 MUC4	1.78e-04	200	116	5	1c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ITSN1 IRS1 KANK2 SSC5D KCNE4	1.78e-04	200	116	5	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	ITSN1 IRS1 KANK2 SSC5D ARHGAP28	1.78e-04	200	116	5	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ITSN1 IRS1 KANK2 SSC5D KCNE4	1.78e-04	200	116	5	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	BPTF SYNE2 KMT2A BOD1L1 SON	1.78e-04	200	116	5	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_3\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	MCM2 MCM3 CDCA7 PTPRZ1 SYNE2	1.78e-04	200	116	5	55a1df656545ff078b727d55e4d65d61ddb5c41f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	MUC16 ANKRD36C RAB11FIP1 CASZ1 MUC4	1.78e-04	200	116	5	03051d2190244208905e1611019d4b8fd200bae0
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MUC16 CASZ1 SYNJ2 PTPRZ1 CCSER1	1.78e-04	200	116	5	85c0f038bcfb42669dca2b80273b0f8a1421405e
Drug	deferoxamine mesylate salt; Down 200; 100uM; PC3; HG-U133A	SART3 DLG5 LRRC40 IRS1 ERBIN LLGL1 KMT2A SON	5.62e-06	197	111	8	460_DN
Drug	Myricetin [529-44-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A	GLB1L KMT2A DEPDC5 TAF1 PEAK1 MAGEC1 MUC4 PDZD2	6.28e-06	200	111	8	4170_UP
Disease	colon cancer (implicated_via_orthology)	NANOGP8 RIOK1 NANOG	8.59e-06	11	112	3	DOID:219 (implicated_via_orthology)
Disease	Familial focal epilepsy with variable foci	NPRL3 DEPDC5	4.27e-05	3	112	2	cv:C1858477
Disease	Epilepsy, Partial, with Variable Foci	NPRL3 DEPDC5	4.27e-05	3	112	2	C1858477
Disease	focal epilepsy (is_implicated_in)	NPRL3 DEPDC5	8.53e-05	4	112	2	DOID:2234 (is_implicated_in)
Disease	hereditary spastic paraplegia 12 (implicated_via_orthology)	RTN4 RTN3	8.53e-05	4	112	2	DOID:0110765 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	CHD8 USP42 KMT2A SON	1.41e-04	69	112	4	DOID:1682 (implicated_via_orthology)
Disease	cerebrospinal fluid biomarker measurement, monocyte chemotactic protein 1 measurement	NIBAN1 EDEM3	2.12e-04	6	112	2	EFO_0006794, EFO_0010596
Disease	Familial Partial Lipodystrophy, Type 3	LIPE AKT2	2.96e-04	7	112	2	C1720861
Disease	Familial Partial Lipodystrophy, Type 2	LIPE AKT2	2.96e-04	7	112	2	C1720860
Disease	Familial Partial Lipodystrophy, Type 1	LIPE AKT2	2.96e-04	7	112	2	C1720859
Disease	arteriovenous malformations of the brain (implicated_via_orthology)	LEMD3 PITPNM3	2.96e-04	7	112	2	DOID:0060688 (implicated_via_orthology)
Disease	Cornelia De Lange Syndrome	BRD4 KMT2A	3.94e-04	8	112	2	C0270972
Disease	Familial partial lipodystrophy	LIPE AKT2	3.94e-04	8	112	2	C0271694
Disease	cancer (implicated_via_orthology)	KANK2 LLGL1 AKT2 DEPDC5 PIPSL CBX2	5.68e-04	268	112	6	DOID:162 (implicated_via_orthology)
Disease	cholesteryl ester 20:4 measurement	CASZ1 NHSL1 PROSER2	6.29e-04	44	112	3	EFO_0010348
Disease	reticulocyte measurement	FXYD5 IRS1 KANK2 RIMKLB USP42 BRD4 SYNE2 NPRL3 ZFAND6 DEPDC5 HDGFL2 PDZD2	6.68e-04	1053	112	12	EFO_0010700
Disease	pro‐interleukin‐16 measurement	IL16 SLC24A2	7.68e-04	11	112	2	EFO_0010629
Disease	Ciliopathies	RPGRIP1 ZNF423 PCARE CEP164	8.33e-04	110	112	4	C4277690
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	LEMD3 SYNE2	9.19e-04	12	112	2	DOID:11726 (implicated_via_orthology)
Disease	susceptibility to common cold measurement	NIBAN1 IL16 ZNF423	1.15e-03	54	112	3	EFO_0008417
Disease	Metastatic melanoma	ALPK3 TAF1 PEAK1	1.15e-03	54	112	3	C0278883
Disease	precuneus cortex volume measurement	NANOGP8 CCSER1	1.26e-03	14	112	2	EFO_0010326
Disease	Disorder of eye	RPGRIP1 ZNF423 PCARE CHM PITPNM3	1.31e-03	212	112	5	C0015397
Disease	mean platelet volume	NIBAN1 PCDHGA7 FXYD5 MCM3 ATG14 IRS1 RIMKLB KCNE4 SYNE2 PROSER2 CAMTA1	1.74e-03	1020	112	11	EFO_0004584
Disease	reticulocyte count	FXYD5 IRS1 KANK2 RIMKLB KCNE4 SYNE2 NPRL3 ZFAND6 DEPDC5 HDGFL2 PDZD2	2.11e-03	1045	112	11	EFO_0007986
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	SYNE2 MAPK8 MUC4 WNK3	2.48e-03	148	112	4	C0279702
Disease	JT interval	RIOK1 KANK2 CASZ1 ALPK3 RAI1	2.60e-03	248	112	5	EFO_0007885
Disease	intellectual disability (implicated_via_orthology)	ITSN1 IRS1 BOD1L1	2.95e-03	75	112	3	DOID:1059 (implicated_via_orthology)
Disease	Parkinson's disease (implicated_via_orthology)	LRRK1 SYNJ2 AKT2 MAPK8	3.07e-03	157	112	4	DOID:14330 (implicated_via_orthology)
Disease	malignant astrocytoma (is_marker_for)	IL16 AKT2	3.43e-03	23	112	2	DOID:3069 (is_marker_for)
Disease	Antihypertensive use measurement	MCM3 INO80 CASZ1 NPRL3 RBM47	3.46e-03	265	112	5	EFO_0009927
Disease	otosclerosis	ALPK3 PEAK1 CCSER1	3.66e-03	81	112	3	EFO_0004213
Disease	Coronary heart disease	ZC3HC1 IRS1	3.73e-03	24	112	2	C0010068
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	TSKS PDZD2	3.73e-03	24	112	2	EFO_0003761, EFO_0005658

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPSDSSTTEEMEVAV	AKT2	126	P31751
PSRMSDSVSLNTDSS	ERBIN	661	Q96RT1
SMDNISDSGASNETT	AKAP2	496	Q9Y2D5
MSDPESVSSVFSDTP	AMIGO1	476	Q86WK6
PRSSSAASMAEEEAS	CHD8	2216	Q9HCK8
SISSGLNSDPDMVDS	CAMTA1	361	Q9Y6Y1
SSDSEDSETEMAPKS	BRD4	711	O60885
RDPADVSSESDSAMT	ATG14	216	Q6ZNE5
EAATSSMLPTSEDTL	CASZ1	216	Q86V15
SESSTMDRSCSSTPV	CASZ1	1366	Q86V15
TAPTMSASSSSDVAS	ALPK3	761	Q96L96
MESSETSCRDLSSSP	PRKAB2	171	O43741
VLQESADMSPASSTT	CCSER1	641	Q9C0I3
DTTSSSSADSTIMDI	FXYD5	26	Q96DB9
CSESDSSVLRMSDPS	BPTF	1266	Q12830
STSSPMEEAISLATD	ASXL3	1711	Q9C0F0
ESDSSNHCMLSPSSS	C18orf25	86	Q96B23
SAFLPTEDESLSTMS	CHM	136	P24386
ESVSTCSVTSPDDMS	RAI1	551	Q7Z5J4
MTAEDSTAAMSSDSA	RBM47	1	A0AV96
NDNAPEVTMTSLSSS	PCDHGA7	341	Q9Y5G6
TAVSAMSSTSAVDPS	EDC4	631	Q6P2E9
ASAMAGPSSETTSEE	H2BW1	26	Q7Z2G1
MSSSSSSPRETYEED	HNRNPLL	1	Q8WVV9
SSSDMLVIVDDPASS	INO80	1376	Q9ULG1
SPLDSSASITMASFS	KIAA1107	1246	Q9UPP5
AALSPMSIDSATSAD	LLGL1	1006	Q15334
PLTDMDSTLDSSTGS	LEMD3	371	Q9Y2U8
MAESSESFTMASSPA	MCM2	1	P49736
SMDSLTSSEESSERP	ANKRD36C	536	Q5JPF3
SSAQSAESSSVAMTP	DEPDC5	1066	O75140
TEEMASTDLDISSPS	MUC16	1466	Q8WXI7
DPSKASSAMTSTSLA	MUC16	2996	Q8WXI7
EEASSVSSSLSSPAM	MUC16	8556	Q8WXI7
TSASASTSPDTAAAM	MUC4	756	Q99102
MEGDSVSSESSSPDV	KCNE4	171	Q8WWG9
ATTDDTTAMASASSS	MAGEA10	346	P43363
TDDSTATESASSSVM	MAGEC1	1121	O60732
ATESASSSVMSPSFS	MAGEC1	1126	O60732
TTDDATAMASASPSV	MAGEC3	621	Q8TD91
SESSDSESLDMAPSD	HLX	376	Q14774
SMAGSEATTTSTADS	MUC22	231	E2RYF6
SSSVPFSTDCEDSDM	LRRK1	1866	Q38SD2
DTTSTSLTPEDTEDM	FYCO1	1316	Q9BQS8
DMDNAASISPSEQTS	EDEM3	851	Q9BZQ6
TNEMESESQPASVTS	NHSL1	1126	Q5SYE7
VNDVSSMSTDPTLAS	MAPK8	396	P45983
SMSTDPTLASDTDSS	MAPK8	401	P45983
TTEVTSASSAMENSP	PDZD2	1696	O15018
MVSSDSTSPDSSLTE	PEAK1	336	Q9H792
SFGSPTSSDDMTLTS	NPRL3	446	Q12980
TSSDDMTLTSPSMDN	NPRL3	451	Q12980
EAMPDLNSSTDSAAS	IL16	1201	Q14005
SVLSTMPSDSESSSS	DLG5	106	Q8TDM6
MPSDSESSSSLSSVG	DLG5	111	Q8TDM6
SMSSPSDIDSFSQAS	MPHOSPH9	331	Q99550
SSMDLLIQDSPDSST	NANOG	56	Q9H9S0
DSEATGSASSAPDSM	KIF26A	1666	Q9ULI4
ANSEPASSDPASSEM	PTPRZ1	1146	P23471
ASSDPASSEMLSPST	PTPRZ1	1151	P23471
MAAASSSSAASASPT	IRS1	1031	P35568
EPVAMARSASSSSSS	HDGFL2	246	Q7Z4V5
SSVSSRASSPDMDEM	OLIG3	6	Q7RTU3
ADIDASSAMDTSEPA	PIPSL	791	A2A3N6
PMTNDSSTLDSLFSS	GRIN3A	546	Q8TCU5
DSMSSDTARTSPVTA	MCM3	601	P25205
STSTAECMPISASID	BOD1L1	2331	Q8NFC6
PEMSAGEESSSSDSD	CBX2	456	Q14781
ASVDSAVAATTPTSM	CUSTOS	201	Q96C57
FSSETAATPMATGDS	EFCAB6	1241	Q5THR3
TNSSEMTESSELATA	FRMPD4	911	Q14CM0
STSMDSGSSESPASL	ITSN1	976	Q15811
NSLSADTLSASEPME	GLB1L	636	Q6UWU2
ESMNISSSSSTEENP	CFAP100	21	Q494V2
APMSDDESPTSSSAE	KANK2	836	Q63ZY3
QMSSDSSRSSSPSVD	KMT2A	471	Q03164
FSSSSSSSPMNKAEE	C4orf54	266	D6RIA3
ADIDASSAMDTSEPA	PSMD4	306	P55036
MATAAETSASEPEAE	SART3	1	Q15020
LAAMAPSITSSEDSS	SCP2D1-AS1	46	Q9BR46
DDGPSQSESATETAM	LRRC40	371	Q9H9A6
QSESATETAMTLPSE	LRRC40	376	Q9H9A6
SDVGSSSDTDSPATM	LIPE	236	Q05469
ETSSDTPEMSLSAET	LIPE	886	Q05469
KTSRPMDASSLSDSE	PCARE	471	A6NGG8
MDASSLSDSEDSSPE	PCARE	476	A6NGG8
GQLSDSDSDMTVAPS	PHAX	11	Q9H814
MSSESSPAALSEADA	FOXD2	11	O60548
NATLSDMVVPSSDSS	KIF13A	1606	Q9H1H9
TSTSMAGAASLSQDS	GARIN3	356	Q8TC56
QTSDSSSAKMSTPAD	RIOK1	96	Q9BRS2
SLCSDEPSSEIMTSS	RTN3	71	O95197
MEDLDQSPLVSSSDS	RTN4	1	Q9NQC3
SSADSSILSASSMFA	SLC5A7	346	Q9GZV3
TTAMEAQTTAPEATE	SELPLG	226	Q14242
ALSTEPSATEALSME	SELPLG	261	Q14242
EESFSEVPMSEASSA	RAB11FIP1	891	Q6WKZ4
LLESMLDSSDSSSQP	RPGRIP1	381	Q96KN7
SMQSTCSPESSEDIT	TEX14	1066	Q8IWB6
STSDNSMAQILTPDS	SYNE2	4171	Q8WXH0
TSSATSPDSDGTKAM	SYNJ2	1386	O15056
NSTSTDVEMTPSSDA	SLC24A2	416	Q9UI40
RKSDASDMNSDTSPS	PROSER2	6	Q86WR7
DFSSSSDSESEMGPQ	TAF1	181	P21675
SSMDLLIQDSPDSST	NANOGP8	56	Q6NSW7
TVSEDTASLMSVADP	SHLD2	21	Q86V20
SSTATSMDPLSTEDF	SSC5D	1396	A1L4H1
ESSTSEGADQKMSSP	SAFB	371	Q15424
ESTSETSDMPEVFSS	SSH3	551	Q8TE77
ISMETSSSSDDSCDS	CDCA7	26	Q9BWT1
MDSLSSESSESFSPP	CEP164	1226	Q9UPV0
SSQPAETDSMSLSEK	ZC3HC1	471	Q86WB0
MTIVDKASESSDPSA	USP42	1	Q9H9J4
AAMAPSTAVSVVSDS	PHF21B	161	Q96EK2
DNMALPSESVSSLTD	NIBAN1	571	Q9BZQ8
PTTSARMESQATSAS	RNF111	396	Q6ZNA4
SEDMAENICSSSSSP	SPATA46	131	Q5T0L3
SMPDDASLNSTTLSD	ARHGAP28	211	Q9P2N2
VPEAQSALDSTSSSM	ZFAND6	71	Q6FIF0
QASESSPDTTAMDTG	TLL2	101	Q9Y6L7
NLAAMEPTDSTGTDS	TSKS	86	Q9UJT2
PASTAVDNMSASSSS	RIMKLB	336	Q9ULI2
VDNMSASSSSVDSDP	RIMKLB	341	Q9ULI2
ESSESSDSMAPVGAS	PITPNM3	526	Q9BZ71
MASIDSSAPETTSDS	ZSWIM8	1141	A7E2V4
EEMLESSDASQSSSV	TASOR2	636	Q5VWN6
ASSTMGDTDSSPSES	TNFRSF1B	401	P20333
LGSVASMSSATPDSS	ZNF423	361	Q2M1K9
SMSSATPDSSASVER	ZNF423	366	Q2M1K9
SSSEKAPDMSSSEEF	HDLBP	1236	Q00341
VAMDTDSETSSPAPS	ZFC3H1	531	O60293
STSTTMDFPESSAIE	SON	321	P18583
PDDVLASDITSTSMS	ZFY	116	P08048
MATDSGDPASTEDSE	WNK3	1	Q9BYP7