Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	high voltage-gated calcium channel activity	CACNA1C CACNA1F CACNA1S	7.85e-06	14	57	3	GO:0008331
GeneOntologyMolecularFunction	protein domain specific binding	NPHS1 DOCK4 JAK2 CACNA1C WT1 SYK CLDN7 NLGN1 PRKDC AR SLC22A12	3.12e-05	875	57	11	GO:0019904
GeneOntologyMolecularFunction	voltage-gated calcium channel activity	CACNA1C CACNA1F CACNA1S	3.07e-04	46	57	3	GO:0005245
GeneOntologyBiologicalProcess	regulation of synaptic transmission, GABAergic	ERBB4 NF1 NLGN2 NLGN1	7.18e-06	45	57	4	GO:0032228
GeneOntologyBiologicalProcess	positive regulation of cell population proliferation	JAK2 IL13 ERBB4 NF1 PTPRN SYK NLGN2 CLDN7 PRKDC AR PTH1R CLDN1 WDR62	1.67e-05	1190	57	13	GO:0008284
GeneOntologyBiologicalProcess	positive regulation of synaptic transmission, GABAergic	ERBB4 NLGN2 NLGN1	2.21e-05	20	57	3	GO:0032230
GeneOntologyBiologicalProcess	synaptic transmission, GABAergic	ERBB4 NF1 NLGN2 NLGN1	5.22e-05	74	57	4	GO:0051932
GeneOntologyBiologicalProcess	mammary gland epithelium development	JAK2 ERBB4 EPHA2 AR	8.58e-05	84	57	4	GO:0061180
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNA1C CACNA1F CACNA1S TMEM262	7.44e-06	46	57	4	GO:0005891
GeneOntologyCellularComponent	calcium channel complex	CACNA1C CACNA1F CACNA1S TMEM262	4.70e-05	73	57	4	GO:0034704
GeneOntologyCellularComponent	inhibitory synapse	ERBB4 NLGN2 NLGN1	8.18e-05	31	57	3	GO:0060077
GeneOntologyCellularComponent	postsynaptic specialization membrane	CACNA1C ERBB4 NLGN2 NLGN1 SLC16A7	2.18e-04	201	57	5	GO:0099634
GeneOntologyCellularComponent	L-type voltage-gated calcium channel complex	CACNA1C CACNA1S	4.74e-04	12	57	2	GO:1990454
GeneOntologyCellularComponent	receptor complex	JAK2 TRBV29-1 ERBB4 EPHA2 SYK NLGN1 PTH1R	9.80e-04	581	57	7	GO:0043235
GeneOntologyCellularComponent	dendritic shaft	CACNA1C NLGN2 NLGN1	1.09e-03	74	57	3	GO:0043198
GeneOntologyCellularComponent	plasma membrane protein complex	JAK2 CACNA1C CACNA1F CACNA1S TRBV29-1 ABCA2 SYK TMEM262	1.24e-03	785	57	8	GO:0098797
GeneOntologyCellularComponent	brush border membrane	PTH1R SLC22A12 SLC3A1	1.51e-03	83	57	3	GO:0031526
GeneOntologyCellularComponent	lamellipodium membrane	EPHA2 PIEZO1	1.63e-03	22	57	2	GO:0031258
GeneOntologyCellularComponent	basolateral plasma membrane	ERBB4 CLDN7 SLC16A7 PTH1R CLDN1	1.78e-03	320	57	5	GO:0016323
GeneOntologyCellularComponent	basal plasma membrane	ERBB4 CLDN7 SLC16A7 PTH1R CLDN1	2.76e-03	354	57	5	GO:0009925
GeneOntologyCellularComponent	excitatory synapse	NLGN2 NLGN1 SLC16A7	3.12e-03	107	57	3	GO:0060076
GeneOntologyCellularComponent	cluster of actin-based cell projections	DOCK4 PTH1R SLC22A12 SLC3A1	3.20e-03	223	57	4	GO:0098862
GeneOntologyCellularComponent	caveola	JAK2 CACNA1C ERBB4	3.46e-03	111	57	3	GO:0005901
GeneOntologyCellularComponent	basal part of cell	ERBB4 CLDN7 SLC16A7 PTH1R CLDN1	3.65e-03	378	57	5	GO:0045178
GeneOntologyCellularComponent	cation channel complex	CACNA1C CACNA1F CACNA1S TMEM262	3.86e-03	235	57	4	GO:0034703
HumanPheno	Abnormal blood cation concentration	CACNA1C CACNA1S NF1 PIEZO1 ABCD3 WT1 SYK PTH1R SLC22A12 SLC3A1	1.38e-05	401	26	10	HP:0010929
HumanPheno	Abnormal blood ion concentration	CACNA1C CACNA1S NF1 PIEZO1 ABCD3 WT1 SYK PTH1R SLC22A12 SLC3A1	3.45e-05	445	26	10	HP:0003111
Domain	VDCC_L_a1su	CACNA1C CACNA1F CACNA1S	1.08e-07	4	57	3	IPR005446
Domain	VDCC_a1su_IQ	CACNA1C CACNA1F CACNA1S	9.35e-07	7	57	3	IPR014873
Domain	GPHH	CACNA1C CACNA1F CACNA1S	9.35e-07	7	57	3	PF16905
Domain	GPHH_dom	CACNA1C CACNA1F CACNA1S	9.35e-07	7	57	3	IPR031649
Domain	Ca_chan_IQ	CACNA1C CACNA1F CACNA1S	9.35e-07	7	57	3	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1F CACNA1S	9.35e-07	7	57	3	PF08763
Domain	VDCCAlpha1	CACNA1C CACNA1F CACNA1S	3.19e-06	10	57	3	IPR002077
Domain	CAC1F_C	CACNA1C CACNA1F	2.74e-05	3	57	2	IPR031688
Domain	CAC1F_C	CACNA1C CACNA1F	2.74e-05	3	57	2	PF16885
Domain	Nlgn	NLGN2 NLGN1	9.10e-05	5	57	2	IPR000460
Domain	TyrKc	JAK2 ERBB4 EPHA2 SYK	1.50e-04	88	57	4	SM00219
Domain	Tyr_kinase_cat_dom	JAK2 ERBB4 EPHA2 SYK	1.50e-04	88	57	4	IPR020635
Domain	PROTEIN_KINASE_TYR	JAK2 ERBB4 EPHA2 SYK	2.19e-04	97	57	4	PS00109
Domain	Tyr_kinase_AS	JAK2 ERBB4 EPHA2 SYK	2.19e-04	97	57	4	IPR008266
Domain	Pkinase_Tyr	JAK2 ERBB4 EPHA2 SYK	6.46e-04	129	57	4	PF07714
Domain	Carboxylesterase_B_CS	NLGN2 NLGN1	6.99e-04	13	57	2	IPR019819
Domain	Channel_four-helix_dom	CACNA1C CACNA1F CACNA1S	7.02e-04	57	57	3	IPR027359
Domain	-	CACNA1C CACNA1F CACNA1S	7.02e-04	57	57	3	1.20.120.350
Domain	CARBOXYLESTERASE_B_2	NLGN2 NLGN1	8.13e-04	14	57	2	PS00941
Domain	COesterase	NLGN2 NLGN1	8.13e-04	14	57	2	PF00135
Domain	CarbesteraseB	NLGN2 NLGN1	8.13e-04	14	57	2	IPR002018
Domain	Ser-Thr/Tyr_kinase_cat_dom	JAK2 ERBB4 EPHA2 SYK	8.32e-04	138	57	4	IPR001245
Domain	Claudin_CS	CLDN7 CLDN1	2.03e-03	22	57	2	IPR017974
Domain	CLAUDIN	CLDN7 CLDN1	2.03e-03	22	57	2	PS01346
Domain	Claudin	CLDN7 CLDN1	3.29e-03	28	57	2	IPR006187
Domain	Ion_trans_dom	CACNA1C CACNA1F CACNA1S	5.10e-03	114	57	3	IPR005821
Domain	Ion_trans	CACNA1C CACNA1F CACNA1S	5.10e-03	114	57	3	PF00520
Domain	Protein_kinase_ATP_BS	JAK2 ERBB4 EPHA2 STK33 SYK	5.91e-03	379	57	5	IPR017441
Domain	Kinase-like_dom	JAK2 ERBB4 EPHA2 STK33 SYK PRKDC	6.02e-03	542	57	6	IPR011009
Domain	PMP22_Claudin	CLDN7 CLDN1	6.63e-03	40	57	2	PF00822
Domain	ABC_transporter_CS	ABCA2 ABCD3	7.29e-03	42	57	2	IPR017871
Domain	PMP22/EMP/MP20/Claudin	CLDN7 CLDN1	8.33e-03	45	57	2	IPR004031
Domain	ABC_tran	ABCA2 ABCD3	9.43e-03	48	57	2	PF00005
Domain	ABC_TRANSPORTER_2	ABCA2 ABCD3	9.43e-03	48	57	2	PS50893
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1F CACNA1S	5.25e-07	6	43	3	M47762
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004	CACNA1C CACNA1F CACNA1S	9.40e-06	14	43	3	M47692
Pathway	KEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY	CACNA1C CACNA1F CACNA1S	4.49e-05	23	43	3	M47666
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNA1C CACNA1F CACNA1S	5.80e-05	25	43	3	M47948
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1F CACNA1S	1.85e-08	4	59	3	20937870
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1F CACNA1S	1.62e-07	7	59	3	12900400
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1C CACNA1F CACNA1S	3.87e-07	9	59	3	16382099
Pubmed	Neuregulin-3 regulates epithelial progenitor cell positioning and specifies mammary phenotype.	ERBB4 AR PTH1R	3.87e-07	9	59	3	24936779
Pubmed	Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.	CACNA1C CACNA1F CACNA1S	2.08e-06	15	59	3	20188150
Pubmed	Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.	CACNA1C CACNA1F CACNA1S	2.08e-06	15	59	3	24453333
Pubmed	Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.	CACNA1C CACNA1S	2.83e-06	2	59	2	25277766
Pubmed	WT1 activates a glomerular-specific enhancer identified from the human nephrin gene.	NPHS1 WT1	2.83e-06	2	59	2	15504938
Pubmed	Sesquiterpene dimmer (DSF-27) inhibits the release of neuroinflammatory mediators from microglia by targeting spleen tyrosine kinase (Syk) and Janus kinase 2 (Jak2): Two major non-receptor tyrosine signaling proteins involved in inflammatory events.	JAK2 SYK	2.83e-06	2	59	2	24486434
Pubmed	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.	CACNA1C CACNA1S	2.83e-06	2	59	2	1281468
Pubmed	Activation of the DNA-dependent protein kinase stimulates nuclear export of the androgen receptor in vitro.	PRKDC AR	2.83e-06	2	59	2	18270197
Pubmed	A Claudin-Based Molecular Signature Identifies High-Risk, Chemoresistant Colorectal Cancer Patients.	CLDN7 CLDN1	2.83e-06	2	59	2	34571860
Pubmed	Claudin-1 interacts with EPHA2 to promote cancer stemness and chemoresistance in colorectal cancer.	EPHA2 CLDN1	2.83e-06	2	59	2	37924938
Pubmed	Homeobox regulator Wilms Tumour 1 is displaced by androgen receptor at cis-regulatory elements in the endometrium of PCOS patients.	WT1 AR	2.83e-06	2	59	2	38745948
Pubmed	Claudin 1 and nephrin label cellular crescents in diabetic glomerulosclerosis.	NPHS1 CLDN1	2.83e-06	2	59	2	24529330
Pubmed	Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.	NLGN2 NLGN1	2.83e-06	2	59	2	19889999
Pubmed	Behavior of CD34+ cells isolated from patients with polycythemia vera in NOD/SCID mice.	JAK2 PRKDC	2.83e-06	2	59	2	17764815
Pubmed	Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.	NLGN2 NLGN1	2.83e-06	2	59	2	10892652
Pubmed	Increased expression of claudin-1 and claudin-7 in liver cirrhosis and hepatocellular carcinoma.	CLDN7 CLDN1	2.83e-06	2	59	2	24696415
Pubmed	Polymorphisms in the CLDN1 and CLDN7 genes are related to differentiation and tumor stage in colon carcinoma.	CLDN7 CLDN1	2.83e-06	2	59	2	24479816
Pubmed	NLGN1 and NLGN2 in the prefrontal cortex: their role in memory consolidation and strengthening.	NLGN2 NLGN1	2.83e-06	2	59	2	29278843
Pubmed	Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.	CACNA1C CACNA1S	2.83e-06	2	59	2	7635187
Pubmed	The decreases of nephrin and nuclear WT1 in podocytes may cause albuminuria during the experimental sepsis in mice.	NPHS1 WT1	2.83e-06	2	59	2	21187647
Pubmed	The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1.	NPHS1 WT1	2.83e-06	2	59	2	15579507
Pubmed	Coexpression of Wilms' tumor suppressor 1 (WT1) and androgen receptor (AR) in the genital tract of human male embryos and regulation of AR promoter activity by WT1.	WT1 AR	2.83e-06	2	59	2	17496156
Pubmed	Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.	CACNA1C CACNA1S	8.48e-06	3	59	2	9668070
Pubmed	Developmental expression and subcellular distribution of synaptotagmin 11 in rat hippocampus.	NLGN2 NLGN1	8.48e-06	3	59	2	22960622
Pubmed	Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.	NLGN2 NLGN1	8.48e-06	3	59	2	28607166
Pubmed	Altered expression of claudin-1, claudin-7, and tricellulin regardless of human papilloma virus infection in human tonsillar squamous cell carcinoma.	CLDN7 CLDN1	8.48e-06	3	59	2	21480761
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1S	8.48e-06	3	59	2	17767505
Pubmed	Wilms tumor-1, claudin-1 and ezrin are useful immunohistochemical markers that help to distinguish schwannoma from fibroblastic meningioma.	WT1 CLDN1	8.48e-06	3	59	2	21909685
Pubmed	Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.	CACNA1C CACNA1S	8.48e-06	3	59	2	11206130
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1S	8.48e-06	3	59	2	2173707
Pubmed	Loss of tight junction proteins (Claudin 1, 4, and 7) correlates with aggressive behavior in colorectal carcinoma.	CLDN7 CLDN1	8.48e-06	3	59	2	25038829
Pubmed	Steroid-resistant nephrotic syndrome: impact of genetic testing.	NPHS1 WT1	8.48e-06	3	59	2	24413855
Pubmed	mRNA for cardiac calcium channel is expressed during development of skeletal muscle.	CACNA1C CACNA1S	8.48e-06	3	59	2	8381753
Pubmed	IL-13 attenuates vascular tube formation via JAK2-STAT6 pathway.	JAK2 IL13	8.48e-06	3	59	2	18296848
Pubmed	Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.	NLGN2 NLGN1	8.48e-06	3	59	2	29100073
Pubmed	Synaptic Adhesion Molecules Regulate the Integration of New Granule Neurons in the Postnatal Mouse Hippocampus and their Impact on Spatial Memory.	NLGN2 NLGN1	8.48e-06	3	59	2	27473321
Pubmed	Cycling hypoxia affects cell invasion and proliferation through direct regulation of claudin1 / claudin7 expression, and indirect regulation of P18 through claudin7.	CLDN7 CLDN1	8.48e-06	3	59	2	28055967
Pubmed	Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.	NLGN2 NLGN1	8.48e-06	3	59	2	26291161
Pubmed	Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.	NLGN2 NLGN1	8.48e-06	3	59	2	17897391
Pubmed	Neuroligins determine synapse maturation and function.	NLGN2 NLGN1	8.48e-06	3	59	2	16982420
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1S	8.48e-06	3	59	2	17289261
Pubmed	Tumor-associated calcium signal transducer 2 is required for the proper subcellular localization of claudin 1 and 7: implications in the pathogenesis of gelatinous drop-like corneal dystrophy.	CLDN7 CLDN1	8.48e-06	3	59	2	20651236
Pubmed	Prolactin and ErbB4/HER4 signaling interact via Janus kinase 2 to induce mammary epithelial cell gene expression differentiation.	JAK2 ERBB4	8.48e-06	3	59	2	18653779
Pubmed	Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.	NLGN2 NLGN1	8.48e-06	3	59	2	27217145
Pubmed	Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency.	JAK2 NF1	8.48e-06	3	59	2	27418650
Pubmed	Expression patterns of claudins 1, 4, and 7 and their prognostic significance in nasopharyngeal carcinoma.	CLDN7 CLDN1	8.48e-06	3	59	2	25778318
Pubmed	Jak2-mediated phosphorylation of Atoh1 is critical for medulloblastoma growth.	JAK2 PRKDC	8.48e-06	3	59	2	29168692
Pubmed	Expression of nephrin, podocin, alpha-actinin, and WT1 in children with nephrotic syndrome.	NPHS1 WT1	8.48e-06	3	59	2	12961083
Pubmed	Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2.	NLGN2 NLGN1	8.48e-06	3	59	2	17582332
Pubmed	Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.	ERBB4 EPHA2 SYK	1.04e-05	25	59	3	15254900
Pubmed	The protein tyrosine kinase family of the human genome.	JAK2 ERBB4 EPHA2 SYK	1.24e-05	83	59	4	11114734
Pubmed	Autism-related deficits via dysregulated eIF4E-dependent translational control.	NLGN2 NLGN1	1.69e-05	4	59	2	23172145
Pubmed	Analysis of NPHS1, NPHS2, ACTN4, and WT1 in Japanese patients with congenital nephrotic syndrome.	NPHS1 WT1	1.69e-05	4	59	2	15780077
Pubmed	Hepatitis C virus envelope components alter localization of hepatocyte tight junction-associated proteins and promote occludin retention in the endoplasmic reticulum.	CLDN7 CLDN1	1.69e-05	4	59	2	18802961
Pubmed	Retrospective mutational analysis of NPHS1, NPHS2, WT1 and LAMB2 in children with steroid-resistant focal segmental glomerulosclerosis - a single-centre experience.	NPHS1 WT1	1.69e-05	4	59	2	24856380
Pubmed	Nephrotic syndrome in the first year of life: two thirds of cases are caused by mutations in 4 genes (NPHS1, NPHS2, WT1, and LAMB2).	NPHS1 WT1	1.69e-05	4	59	2	17371932
Pubmed	Identification of claudin‑1, ‑3, ‑7 and ‑8 as prognostic markers in human laryngeal carcinoma.	CLDN7 CLDN1	1.69e-05	4	59	2	31115553
Pubmed	Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.	NLGN2 NLGN1	1.69e-05	4	59	2	30056576
Pubmed	Expression of claudins-1, -4, -5, -7 and occludin in hepatocellular carcinoma and their relation with classic clinicopathological features and patients' survival.	CLDN7 CLDN1	1.69e-05	4	59	2	24815833
Pubmed	Transcription of nephrin-Neph3 gene pair is synergistically activated by WT1 and NF-κB and silenced by DNA methylation.	NPHS1 WT1	1.69e-05	4	59	2	21980157
Pubmed	Neuroligin 2 regulates absence seizures and behavioral arrests through GABAergic transmission within the thalamocortical circuitry.	NLGN2 NLGN1	1.69e-05	4	59	2	32719346
Pubmed	Diverse regulation of claudin-1 and claudin-4 in atopic dermatitis.	CLDN7 CLDN1	1.69e-05	4	59	2	26319240
Pubmed	Neurotransmitter release regulated by a MALS-liprin-alpha presynaptic complex.	ERBB4 NLGN2 NLGN1	1.82e-05	30	59	3	16186258
Pubmed	5-HT modulation of a medial septal circuit tunes social memory stability.	NLGN2 NLGN1	2.82e-05	5	59	2	34616037
Pubmed	Expression of epidermal growth factors and a tight junction protein in the nasal mucosa of patients with chronic hypertrophic rhinitis.	ERBB4 CLDN1	2.82e-05	5	59	2	23137868
Pubmed	Distinct claudin expression profile in histologic subtypes of lung cancer.	CLDN7 CLDN1	2.82e-05	5	59	2	17418912
Pubmed	Mice with a Pax2 missense variant display impaired glomerular repair.	NPHS1 WT1	2.82e-05	5	59	2	38482556
Pubmed	Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.	NLGN2 NLGN1	2.82e-05	5	59	2	27581450
Pubmed	Expression of occludin and claudins 1, 3, 4, and 7 in urothelial carcinoma of the upper urinary tract.	CLDN7 CLDN1	2.82e-05	5	59	2	18550469
Pubmed	Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.	NLGN2 NLGN1	2.82e-05	5	59	2	15620359
Pubmed	Divergent expression of claudin -1, -3, -4, -5 and -7 in developing human lung.	CLDN7 CLDN1	2.82e-05	5	59	2	20478039
Pubmed	Neuroligin-induced presynaptic differentiation through SLM2-mediated splicing modifications of neurexin in cerebellar cultures.	NLGN2 NLGN1	2.82e-05	5	59	2	28939043
Pubmed	Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.	NLGN2 NLGN1	2.82e-05	5	59	2	37865312
Pubmed	DNA-PKcs-Mediated Transcriptional Regulation Drives Prostate Cancer Progression and Metastasis.	PRKDC AR	2.82e-05	5	59	2	26175416
Pubmed	Parathyroid hormone-related protein signaling is necessary for sexual dimorphism during embryonic mammary development.	AR PTH1R	2.82e-05	5	59	2	10409496
Pubmed	Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development.	NLGN2 NLGN1	2.82e-05	5	59	2	23358245
Pubmed	Alteration of tight junction proteins is an early event in psoriasis: putative involvement of proinflammatory cytokines.	CLDN7 CLDN1	2.82e-05	5	59	2	19661441
Pubmed	Synapse formation: if it looks like a duck and quacks like a duck ...	NLGN2 NLGN1	2.82e-05	5	59	2	10996085
Pubmed	Mutation analysis of five candidate genes in Chinese patients with hypospadias.	WT1 AR	2.82e-05	5	59	2	15266301
Pubmed	Planar cell polarity pathway regulates nephrin endocytosis in developing podocytes.	NPHS1 WT1	2.82e-05	5	59	2	23824190
Pubmed	Ret is critical for podocyte survival following glomerular injury in vivo.	NPHS1 WT1	2.82e-05	5	59	2	25587123
Pubmed	The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1.	CACNA1C CACNA1S	2.82e-05	5	59	2	1335956
Pubmed	TGFβR-SMAD3 Signaling Induces Resistance to PARP Inhibitors in the Bone Marrow Microenvironment.	JAK2 PRKDC	2.82e-05	5	59	2	33027668
Pubmed	Phosphoproteome analysis of the human mitotic spindle.	NDC1 NF1 PIEZO1 PRKDC WDR62	2.94e-05	210	59	5	16565220
Pubmed	The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?	NLGN2 NLGN1	4.23e-05	6	59	2	21838267
Pubmed	Impairment of Inhibitory Synapse Formation and Motor Behavior in Mice Lacking the NL2 Binding Partner LHFPL4/GARLH4.	NLGN2 NLGN1	4.23e-05	6	59	2	29742426
Pubmed	SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance.	NPHS1 WT1	4.23e-05	6	59	2	33514561
Pubmed	Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.	NLGN2 NLGN1	4.23e-05	6	59	2	29724786
Pubmed	LKB1/STK11 Is a Tumor Suppressor in the Progression of Myeloproliferative Neoplasms.	JAK2 PRKDC	4.23e-05	6	59	2	33579786
Pubmed	Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn.	NLGN2 NLGN1	4.23e-05	6	59	2	19816407
Pubmed	Ephexin4 and EphA2 mediate cell migration through a RhoG-dependent mechanism.	DOCK4 EPHA2	4.23e-05	6	59	2	20679435
Pubmed	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	NLGN2 NLGN1	4.23e-05	6	59	2	8576240
Pubmed	HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2.	NPHS1 WT1 CLDN1	4.38e-05	40	59	3	23362348
Pubmed	EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.	JAK2 CLDN7 CLDN1	5.84e-05	44	59	3	35493520
Pubmed	Tumor suppressor gene mutations in mice.	NF1 WT1	5.91e-05	7	59	2	8982467
Pubmed	Role of Asxl1 in kidney podocyte development via its interaction with Wtip.	NPHS1 WT1	5.91e-05	7	59	2	26385183
Pubmed	Repression of CMIP transcription by WT1 is relevant to podocyte health.	NPHS1 WT1	5.91e-05	7	59	2	27650733
GeneFamily	Calcium voltage-gated channel subunits	CACNA1C CACNA1F CACNA1S	2.52e-05	26	40	3	253
GeneFamily	Claudins	CLDN7 CLDN1	1.17e-03	23	40	2	488
CoexpressionAtlas	DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#4_top-relative-expression-ranked_1000	GPR155 MGAM TMEM150A FADS3 SLC22A12 SLC3A1	1.55e-05	207	55	6	gudmap_developingKidney_e15.5_Proximal Tubules_1000_k4
CoexpressionAtlas	kidney single cell_adult_RenalCortexMixed_StemCellamp_k-means-cluster#3_top-relative-expression-ranked_200	TMEM150A FADS3 PTH1R SLC22A12 SLC3A1	4.31e-05	150	55	5	gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_k3_200
CoexpressionAtlas	kidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_1000	MGAM ERBB4 FADS3 MTFR1 ABCD3 SLC16A7 AR PTH1R CLDN1 SLC3A1	6.36e-05	861	55	10	gudmap_kidney_adult_RenalCortexMixed_Std_1000
CoexpressionAtlas	kidney single cell_adult_RenalCortexMixed_StemCellamp_top-relative-expression-ranked_200	TMEM150A FADS3 PTH1R SLC22A12 SLC3A1	6.58e-05	164	55	5	gudmap_kidney single cell_adult_RenalCortexMixed_Scamp_200
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ERBB4 WDR87 EPHA2 CYP4X1 CLDN1	2.09e-06	157	59	5	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR155 MGAM NLGN1 PTH1R SLC22A12	3.96e-06	179	59	5	78fae47ec9bff4e0159a86a281e831d7f8ee925a
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C ERBB4 FADS3 STK33 CLDN1	4.42e-06	183	59	5	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	COVID-19-kidney-PCT-S1/S2\|kidney / Disease (COVID-19 only), tissue and cell type	GPR155 NLGN1 PTH1R SLC22A12 SLC3A1	4.53e-06	184	59	5	dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GPR155 MGAM NLGN1 SLC22A12 SLC3A1	4.53e-06	184	59	5	9434731f651820b05335085582960f08fbf895de
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NPHS1 ERBB4 WT1 CYP4X1 CLDN1	4.66e-06	185	59	5	492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 FADS3 B3GALNT2 URB2 SLC16A7	4.78e-06	186	59	5	77bebf576eb9b96ecb4fefb8a82a31aaaa917fc0
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DOCK4 FADS3 B3GALNT2 URB2 SLC16A7	4.78e-06	186	59	5	13bc41c60fd628af31899a5e8b480e06cc4781be
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NPHS1 ERBB4 WT1 CYP4X1 CLDN1	5.04e-06	188	59	5	9655a4c47b644a870017d349b99063e17dbae572
ToppCell	COPD-Epithelial\|COPD / Disease state, Lineage and Cell class	ERBB4 EPHA2 STK33 CYP4X1 CLDN1	5.58e-06	192	59	5	0644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 STK33 NLGN1 PTH1R SLC3A1	5.72e-06	193	59	5	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC7 EPHA2 ABCD3 CLDN7 SLC16A7	5.87e-06	194	59	5	1531dcace28a14bd700e909a027426a8cee20337
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 STK33 NLGN1 PTH1R SLC3A1	5.87e-06	194	59	5	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	RA-06._Ventricular_Cardiomyocyte_II\|RA / Chamber and Cluster_Paper	CACNA1C ERBB4 CLDN7 CLDN1	2.84e-05	132	59	4	82674ec4b0a416e4f08372b86c2a475afe3f38a5
ToppCell	TCGA-Kidney\|World / Sample_Type by Project: Shred V9	MGAM PTH1R SLC22A12 SLC3A1	4.81e-05	151	59	4	e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCell	facs-Liver-Hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCD3 SLC16A7 SERPIND1 CLDN1	5.46e-05	156	59	4	e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 WT1 PTH1R SLC22A12	5.88e-05	159	59	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gpr149_Islr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DOCK4 ERBB4 PIP5KL1 PTH1R	5.88e-05	159	59	4	c64fff8d89f84d1f5a0cc432e31f56f741162505
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IL13 ABCA2 ASTE1 AR	5.88e-05	159	59	4	f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 WT1 PTH1R SLC22A12	5.88e-05	159	59	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 WT1 PTH1R SLC22A12	5.88e-05	159	59	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	facs-Heart-RA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC7 CLDN7 DMBT1 SLC3A1	6.47e-05	163	59	4	13557be854878abc1bcdab909b49b8292d064145
ToppCell	facs-Heart-RA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC7 CLDN7 DMBT1 SLC3A1	6.47e-05	163	59	4	6c1d1646410e785886d2de103b4b12f73e91edff
ToppCell	facs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150A PTH1R SLC22A12 SLC3A1	6.78e-05	165	59	4	906321cb5f299d77436fb5540fd8c52d7532beca
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 NDC1 DMBT1 CLDN1	6.78e-05	165	59	4	622aca1d49bd8c917b131e4f4959d9dba411d22b
ToppCell	facs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150A PTH1R SLC22A12 SLC3A1	6.78e-05	165	59	4	02a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 NDC1 DMBT1 CLDN1	7.11e-05	167	59	4	3c06894fc6177f3c204094719904da42f08b9af8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CACNA1S WT1 PTH1R	7.27e-05	168	59	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CACNA1S WT1 PTH1R	7.27e-05	168	59	4	315ca578c945aeeb77acda2727f3e6db8b43f43e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NPHS1 CACNA1S WT1 PTH1R	7.27e-05	168	59	4	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NPHS1 WT1 NLGN1 CLDN1	7.27e-05	168	59	4	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype-7\|TCGA-Lung / Sample_Type by Project: Shred V9	TMEM150A PIP5KL1 PNMA2 SLC16A7	7.44e-05	169	59	4	5f522a10b6ec24a353f53bec2f779a81cd5f9581
ToppCell	3'_v3-Lung-Myeloid_Mac-Intestinal_macrophages\|Lung / Manually curated celltypes from each tissue	DOCK4 GPR155 ERBB4 CLDN1	7.44e-05	169	59	4	241644823e6f949aaf4c671d4579721d7ef6b0e5
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9\|TCGA-Bladder / Sample_Type by Project: Shred V9	EPHA2 CYP4X1 CLDN1 TGM5	7.79e-05	171	59	4	adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM NLGN1 PTH1R SLC22A12	8.71e-05	176	59	4	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	ERBB4 STK33 NLGN1 SLC3A1	8.71e-05	176	59	4	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	JAK2 CACNA1S XKR7 PTH1R	8.90e-05	177	59	4	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	EFHC2 DOCK4 TMC7 STK33	9.10e-05	178	59	4	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	COVID-19-kidney-PCT-S1/S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NLGN1 PTH1R SLC22A12 SLC3A1	9.10e-05	178	59	4	23a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERBB4 WT1 NLGN1 CLDN1	9.10e-05	178	59	4	544379f5a6145429762258d426b876bb36c112f5
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	JAK2 SZT2 CLDN7 CLDN1	9.29e-05	179	59	4	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NLGN1 PTH1R SLC22A12 SLC3A1	9.50e-05	180	59	4	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 PIP5KL1 WT1 TGM5	9.50e-05	180	59	4	35c73670da90cb6924e822a2426d13a675685f09
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 WT1 CLDN1 TGM5	9.70e-05	181	59	4	3dcb74b28f93be35ddf4de1937f7e30b25e11927
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1F FADS3 NLGN1 PTH1R	9.70e-05	181	59	4	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR155 CACNA1S TMEM150A CLDN7	9.70e-05	181	59	4	97022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NPHS1 WT1 CLDN1 TGM5	9.70e-05	181	59	4	7679a5980011d6dfb1aaca7abf678c29b6f819bb
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150A PTH1R SLC22A12 SLC3A1	9.91e-05	182	59	4	faf0dfa3adc2d2706b6942b5127093ccdc856447
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150A PTH1R SLC22A12 SLC3A1	9.91e-05	182	59	4	be8dd52898525ce6632af0adc2801944f3ac10bd
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ASTE1 CLDN7 DMBT1 CLDN1	9.91e-05	182	59	4	9174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERBB4 NLGN1 PTH1R SLC3A1	9.91e-05	182	59	4	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NLGN2 NLGN1 PTH1R CLDN1	1.01e-04	183	59	4	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 PTH1R SLC22A12 SLC3A1	1.03e-04	184	59	4	3d7dd193a0826cc7a4e454a29236a16c315e5965
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FADS3 PTH1R SLC22A12 SLC3A1	1.03e-04	184	59	4	45577ff91c3b2b303acd97239dde2463ea7a429c
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____kidney_capillary_endothelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPHS1 TRIM69 TMC7 WT1	1.03e-04	184	59	4	1c857126c0ea0671f0d60b048efca288d348d653
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR155 CACNA1S TMEM150A CLDN7	1.06e-04	185	59	4	238938a4682b44e88a30b86b13af4feeabe9553d
ToppCell	droplet-Thymus-nan-24m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S TMEM150A FADS3 CLDN7	1.06e-04	185	59	4	e583f6601f9ed79b0b23d2f9426a4ba8b969230b
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	URB1 NDC1 PRKDC SLC16A7	1.06e-04	185	59	4	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NLGN1 PTH1R SLC22A12 SLC3A1	1.06e-04	185	59	4	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MGAM NLGN1 PTH1R SLC22A12	1.08e-04	186	59	4	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NPHS1 ERBB4 WT1 CLDN1	1.10e-04	187	59	4	8e8f1f2a78ac5f13a414fd448af7d7ff1ea86f0f
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EPHA2 CYP4X1 CLDN7 DMBT1	1.10e-04	187	59	4	71d99a1a95d3692a2891da49d4a243bae6e07fd0
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ERBB4 NLGN1 PTH1R SLC3A1	1.10e-04	187	59	4	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	droplet-Spleen-nan-21m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR155 CACNA1S TMEM150A CLDN7	1.12e-04	188	59	4	70184b14160b71a1fecd7f195e5a16c5937738a2
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C ERBB4 STK33 NLGN1	1.15e-04	189	59	4	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CLDN7 DMBT1 SERPIND1 CLDN1	1.15e-04	189	59	4	e90ba6f6d7ba0698d04d84278aa035c28803733e
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	JAK2 CACNA1C NLGN1 SLC16A7	1.15e-04	189	59	4	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA2 STK33 WT1 CLDN1	1.15e-04	189	59	4	319e42f6e2322208de78bc666fb2c074707eb4da
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CACNA1C ERBB4 NLGN1 SLC16A7	1.17e-04	190	59	4	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	JAK2 CACNA1C WT1 NLGN1	1.17e-04	190	59	4	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	CACNA1C ERBB4 STK33 NLGN1	1.17e-04	190	59	4	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	CACNA1C ERBB4 NLGN1 SLC16A7	1.19e-04	191	59	4	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	367C-Epithelial_cells\|367C / Donor, Lineage, Cell class and subclass (all cells)	STK33 CYP4X1 CLDN7 DMBT1	1.19e-04	191	59	4	d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCell	facs-Trachea-nan-18m-Epithelial-keratinocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF37 CLDN1 TGM5 WDR62	1.22e-04	192	59	4	4530b3028928d089b3a71eb19a4df237f58a50ae
ToppCell	facs-Trachea-nan-18m-Epithelial-new-cluster\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF37 CLDN1 TGM5 WDR62	1.22e-04	192	59	4	e4fb3f18da7dc6a835023db69a8d99737c39ef86
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|LV / Chamber and Cluster_Paper	ERBB4 STK33 NLGN1 SLC16A7	1.22e-04	192	59	4	ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 STK33 NLGN1 PTH1R	1.24e-04	193	59	4	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 STK33 NLGN1 PTH1R	1.27e-04	194	59	4	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF37 CLDN1 TGM5 WDR62	1.27e-04	194	59	4	bd94d30584128628b34ed8c3857ce103586cfe2e
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-keratinocyte-new-cluster\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGEF37 CLDN1 TGM5 WDR62	1.27e-04	194	59	4	b847c5b4e8914b1c306bfff3d7119c32063784a8
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-plasma_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR155 CACNA1S TMEM150A CLDN7	1.29e-04	195	59	4	f9a90cd7b4e99a0947fdb3645f7787d02b0f7ca0
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MGAM XKR7 WT1	1.30e-04	74	59	3	ef4c9eafc794c7d50aef28b37d21b52d3c511499
ToppCell	Substantia_nigra-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6_(Thalamus,_glutamatergic)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MGAM XKR7 WT1	1.30e-04	74	59	3	6ecbdf4186039a031410e09ecd5afa66b6d5e2dc
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA2 PIEZO1 CLDN7 CLDN1	1.32e-04	196	59	4	22fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 STK33 NLGN1 SLC3A1	1.32e-04	196	59	4	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CACNA1F FADS3 CLDN7 PTH1R	1.34e-04	197	59	4	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 SLC16A7 PTH1R SLC3A1	1.34e-04	197	59	4	4ea3f57cd88b8a6bb7cb4b9e3545c0fa8f331886
ToppCell	5'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MGAM CLDN7 DMBT1 SLC3A1	1.37e-04	198	59	4	8d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell	medial-2-Epithelial-Alveolar_Epithelial_Type_2\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLDN7 DMBT1 SERPIND1 CLDN1	1.37e-04	198	59	4	102a4cbb138adbfba11ed955420095daa098532f
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_2-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLDN7 DMBT1 SERPIND1 CLDN1	1.37e-04	198	59	4	7caeed2d5dc78866023c8f38edcec9886baa9f2c
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CACNA1F FADS3 CYP4X1 PTH1R	1.37e-04	198	59	4	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	medial-Epithelial-Alveolar_Epithelial_Type_2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CLDN7 DMBT1 SERPIND1 CLDN1	1.37e-04	198	59	4	53e5d76831d70b9a476f3ef3a81e13eda974d543
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EPHA2 CYP4X1 CLDN7 DMBT1	1.40e-04	199	59	4	527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CACNA1F FADS3 NLGN1 PTH1R	1.40e-04	199	59	4	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 PTH1R SLC22A12 SLC3A1	1.40e-04	199	59	4	f38e7bc3dc0e7822bee2df5634bf47a5c7145d60
ToppCell	LPS_only-Epithelial_alveolar-AT_1-AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	FADS3 EPHA2 CLDN7 PTH1R	1.40e-04	199	59	4	ccdde5d4bcc72f230a1dd2544ee7f4dfb98a5e80
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_2\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	EPHA2 CYP4X1 CLDN7 CLDN1	1.42e-04	200	59	4	c7668e26c6b8cfa6d174b0634e43c230425faba9
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	EPHA2 CYP4X1 CLDN7 CLDN1	1.42e-04	200	59	4	bce9bce9eb622bc6514708d49ca4a6604043c22a
ToppCell	Tracheal-10x5prime-Epithelial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EPHA2 CYP4X1 CLDN7 CLDN1	1.42e-04	200	59	4	efd461c687155c84ef590352207e6fe4ba392a90
ToppCell	Tracheal-10x3prime_v2-Epithelial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	STK33 CYP4X1 CLDN7 CLDN1	1.42e-04	200	59	4	e1da1b15d2ca06796ee1ab7cef586ae0b4dc0a0a
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	ABCA2 NF1 TMC7 EPHA2 URB2 AR WDR62	7.48e-07	200	58	7	6996_DN
Drug	enzacamene	CACNA1C CACNA1F ERBB4 NF1 NLGN1 AR	9.36e-07	129	58	6	ctd:C038939
Drug	Cinnarizine	CACNA1C CACNA1F CACNA1S	1.30e-06	9	58	3	DB00568
Drug	Nimodipine	CACNA1C CACNA1F CACNA1S	1.30e-06	9	58	3	DB00393
Drug	Mibefradil	CACNA1C CACNA1F CACNA1S	2.55e-06	11	58	3	DB01388
Drug	butylparaben	CACNA1C CACNA1F ERBB4 NF1 NLGN1 AR	2.94e-06	157	58	6	ctd:C038091
Drug	Verapamil	CACNA1C CACNA1F CACNA1S	8.58e-06	16	58	3	DB00661
Drug	Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; PC3; HT_HG-U133A	JAK2 ABCA2 NF1 TMC7 SZT2 WDR62	1.11e-05	198	58	6	7126_UP
Drug	Linuron	CACNA1C ERBB4 NF1 NLGN1 AR	1.87e-05	128	58	5	ctd:D008044
Drug	methoxycarbonylcholine	MGAM PNMA2	1.91e-05	3	58	2	CID000129824
Drug	phenyl -maltoside	MGAM SLC3A1	1.91e-05	3	58	2	CID003081956
Drug	lanthanum	CACNA1C CACNA1F CACNA1S MGAM CLDN1	2.51e-05	136	58	5	CID000023926
Drug	gallopamil	CACNA1C CACNA1F CACNA1S MGAM	2.58e-05	67	58	4	CID000001234
Drug	octylmethoxycinnamate	CACNA1C CACNA1F ERBB4 NF1 NLGN1	2.79e-05	139	58	5	ctd:C118580
Drug	MgSO4.7H2O	CACNA1C CACNA1S MGAM	3.47e-05	25	58	3	CID000024843
Drug	DBNPA	MGAM SLC3A1	3.81e-05	4	58	2	CID000025059
Drug	isomaltoheptaose	MGAM SLC3A1	3.81e-05	4	58	2	CID003081403
Drug	Bay K 8644	CACNA1C CACNA1F CACNA1S MGAM NF1	4.02e-05	150	58	5	CID000002303
Drug	Androgen Antagonists	CACNA1C ERBB4 NF1 NLGN1	4.03e-05	75	58	4	ctd:D000726
Drug	procymidone	CACNA1C ERBB4 NF1 NLGN1 AR	4.70e-05	155	58	5	ctd:C035988
Drug	Nisoldipine	CACNA1C CACNA1S	6.35e-05	5	58	2	DB00401
Drug	AC1L53LJ	MGAM SLC3A1	6.35e-05	5	58	2	CID000197521
Drug	anthroylouabain	MGAM WT1	6.35e-05	5	58	2	CID000124910
Drug	Nilvadipine	CACNA1C CACNA1S	6.35e-05	5	58	2	DB06712
Drug	Lycorine hydrochloride [2188-68-3]; Up 200; 12.4uM; MCF7; HT_HG-U133A	URB1 EPHA2 URB2 DMBT1 CLDN1	6.88e-05	168	58	5	4365_UP
Drug	EKB-569	JAK2 IL13 ERBB4 SYK	7.21e-05	87	58	4	CID006445562
Drug	lavendustin A	JAK2 CACNA1C CACNA1F CACNA1S ERBB4	7.49e-05	171	58	5	CID000003894
Drug	CNS 1145	CACNA1C CACNA1F CACNA1S	8.11e-05	33	58	3	CID000190902
Drug	IHC-64	CACNA1C CACNA1F CACNA1S	8.11e-05	33	58	3	CID000162753
Drug	CPU-23	CACNA1C CACNA1S	9.50e-05	6	58	2	CID003036051
Drug	Magnesium Sulfate	CACNA1C CACNA1S	9.50e-05	6	58	2	DB00653
Drug	retinoic acid; Down 200; 1uM; HL60; HT_HG-U133A	MGAM URB1 PIEZO1 WT1 URB2	9.53e-05	180	58	5	1152_DN
Drug	Prednisone	NPHS1 IL13 AR	9.69e-05	35	58	3	ctd:D011241
Drug	Sanguinarine [2447-54-3]; Down 200; 12uM; HL60; HT_HG-U133A	PIEZO1 WT1 SYK PRKDC TGM5	1.08e-04	185	58	5	2927_DN
Drug	isotetrandrine	CACNA1C CACNA1F CACNA1S SLC22A12	1.10e-04	97	58	4	CID000005422
Drug	Alprostadil [745-65-3]; Up 200; 11.2uM; PC3; HT_HG-U133A	JAK2 ABCA2 NF1 DMBT1 SERPIND1	1.20e-04	189	58	5	4099_UP
Drug	5253409; Up 200; 17uM; MCF7; HT_HG-U133A_EA	DOCK4 URB1 NF1 CLDN1 WDR62	1.23e-04	190	58	5	961_UP
Drug	Amlodipine	CACNA1C CACNA1S	1.33e-04	7	58	2	DB00381
Drug	Isradipine	CACNA1C CACNA1S	1.33e-04	7	58	2	DB00270
Drug	oxyfluorofen	ABCD3 AR	1.33e-04	7	58	2	ctd:C016027
Drug	Fp 3	MGAM NF1	1.33e-04	7	58	2	CID000203335
Drug	isomaltotetraose	MGAM SLC3A1	1.33e-04	7	58	2	CID003080783
Drug	ICI 182,780; Down 200; 1uM; PC3; HT_HG-U133A	URB1 ABCA2 WT1 SLC16A7 SLC3A1	1.36e-04	194	58	5	4429_DN
Drug	5252917; Up 200; 14uM; MCF7; HT_HG-U133A_EA	HOXA6 FADS3 SYK NLGN1 CLDN1	1.36e-04	194	58	5	828_UP
Drug	Ozagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A	JAK2 ABCA2 SZT2 MTFR1 PIEZO1	1.39e-04	195	58	5	2942_UP
Drug	estradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A	DOCK4 JAK2 FADS3 DMBT1 PTH1R	1.39e-04	195	58	5	5568_UP
Drug	Dihydrostreptomycin sulfate [5490-27-7]; Down 200; 2.8uM; PC3; HT_HG-U133A	URB1 NF1 FADS3 TMC7 WT1	1.42e-04	196	58	5	5751_DN
Drug	Pyrantel tartrate [33401-94-4]; Up 200; 11.2uM; PC3; HT_HG-U133A	IL13 URB1 NF1 SZT2 PTH1R	1.42e-04	196	58	5	5088_UP
Drug	Rauwolscine hydrochloride [6211-32-1]; Up 200; 10.2uM; MCF7; HT_HG-U133A	DOCK4 JAK2 IL13 NF1 SLC3A1	1.42e-04	196	58	5	2778_UP
Drug	Lc 6	PNMA2 PTH1R SLC3A1	1.45e-04	40	58	3	CID000106696
Drug	Sisomicin sulfate [53179-09-2]; Up 200; 2.8uM; PC3; HT_HG-U133A	HOXA6 JAK2 URB1 NF1 SLC16A7	1.46e-04	197	58	5	4014_UP
Drug	Hyoscyamine (L) [101-31-5]; Up 200; 13.8uM; PC3; HT_HG-U133A	CACNA1S URB1 NF1 SYK SLC16A7	1.46e-04	197	58	5	5099_UP
Drug	Naringenine [480-41-1]; Up 200; 14.6uM; MCF7; HT_HG-U133A	JAK2 URB1 NF1 SYK SLC3A1	1.49e-04	198	58	5	4422_UP
Drug	Chlorhexidine [55-56-1]; Up 200; 8uM; PC3; HG-U133A	CACNA1S IL13 FADS3 PTH1R WDR62	1.49e-04	198	58	5	1942_UP
Drug	Pempidine tartrate [546-48-5]; Down 200; 13uM; MCF7; HT_HG-U133A	URB1 ABCA2 NF1 TMC7 EPHA2	1.49e-04	198	58	5	6027_DN
Drug	Etofylline [519-37-9]; Up 200; 17.8uM; PC3; HT_HG-U133A	ABCA2 NF1 SZT2 WT1 SLC16A7	1.53e-04	199	58	5	5048_UP
Drug	Nifedipine	CACNA1C CACNA1S	1.77e-04	8	58	2	DB01115
Drug	Nitrendipine	CACNA1C CACNA1S	1.77e-04	8	58	2	DB01054
Drug	MA-8	NF1 PNMA2	1.77e-04	8	58	2	CID005327116
Drug	maltulose	MGAM SLC16A7 CLDN1	2.06e-04	45	58	3	CID000087177
Drug	AC1L9IXX	MGAM EPHA2 PNMA2	2.06e-04	45	58	3	CID000446000
Drug	AC1NBU2S	CACNA1C CACNA1F CACNA1S MGAM	2.27e-04	117	58	4	CID004473765
Drug	leucrose	MGAM SLC3A1	2.27e-04	9	58	2	CID000165577
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1F CACNA1S	2.73e-08	4	57	3	DOID:0060173 (implicated_via_orthology)
Disease	Autistic Disorder	DOCK4 GPR155 CACNA1C IL13 NF1 NLGN1 AR	7.09e-07	261	57	7	C0004352
Disease	Mesenteric Vascular Occlusion	JAK2 SERPIND1	3.67e-06	2	57	2	C0025472
Disease	leukemia	JAK2 NF1 WT1 AR	3.96e-06	55	57	4	C0023418
Disease	Squamous cell carcinoma of lung	ERBB4 EPHA2 PRKDC	3.26e-05	32	57	3	C0149782
Disease	Schwannomatosis, Plexiform	NF1 WT1	3.65e-05	5	57	2	C0751374
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1C CACNA1F CACNA1S	4.66e-05	36	57	3	DOID:11723 (implicated_via_orthology)
Disease	Neurilemmoma	NF1 WT1	5.47e-05	6	57	2	C0027809
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	NPHS1 WT1	2.82e-04	13	57	2	cv:C4273714
Disease	diastolic blood pressure, body mass index	EFHC2 CACNA1S	4.32e-04	16	57	2	EFO_0004340, EFO_0006336
Disease	Lung diseases	IL13 PRKDC PTH1R	4.69e-04	78	57	3	C0024115
Disease	Pseudopelade	AR CLDN1	6.14e-04	19	57	2	C0086873
Disease	serotonin measurement	ERBB4 OR13D1	8.26e-04	22	57	2	EFO_0004846
Disease	alcohol use disorder measurement, alcohol consumption measurement	CACNA1C NF1 STK33	8.86e-04	97	57	3	EFO_0007878, EFO_0009458
Disease	Renal glomerular disease	NPHS1 WT1	9.04e-04	23	57	2	C0268731
Disease	Glomerulopathy Assessment	NPHS1 WT1	9.04e-04	23	57	2	C4521256
Disease	Noonan Syndrome	NF1 EPHA2	9.85e-04	24	57	2	C0028326
Disease	Cerebral Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0750935
Disease	Intracranial Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0750936
Disease	Pilocytic Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0334583
Disease	Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0280783
Disease	Diffuse Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0280785
Disease	Grade I Astrocytoma	NF1 AR	1.07e-03	25	57	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0205768
Disease	Mixed oligoastrocytoma	NF1 AR	1.07e-03	25	57	2	C0547065
Disease	Childhood Cerebral Astrocytoma	NF1 AR	1.07e-03	25	57	2	C0338070
Disease	atopic dermatitis (is_implicated_in)	IL13 CLDN1	1.16e-03	26	57	2	DOID:3310 (is_implicated_in)
Disease	Gemistocytic astrocytoma	NF1 AR	1.16e-03	26	57	2	C0334581
Disease	Protoplasmic astrocytoma	NF1 AR	1.16e-03	26	57	2	C0334580
Disease	Fibrillary Astrocytoma	NF1 AR	1.16e-03	26	57	2	C0334582
Disease	psychosis predisposition measurement	CACNA1C TMC7	1.16e-03	26	57	2	EFO_0008337
Disease	Anaplastic astrocytoma	NF1 AR	1.25e-03	27	57	2	C0334579
Disease	Myeloid Leukemia, Chronic	JAK2 WT1	1.44e-03	29	57	2	C0023473
Disease	Crohn's disease (is_implicated_in)	JAK2 CLDN1	1.54e-03	30	57	2	DOID:8778 (is_implicated_in)
Disease	NEPHROTIC SYNDROME, STEROID-RESISTANT, AUTOSOMAL RECESSIVE	NPHS1 WT1	1.54e-03	30	57	2	C1868672
Disease	Bright Disease	NPHS1 WT1	1.64e-03	31	57	2	C1704377
Disease	Glomerulonephritis	NPHS1 WT1	1.64e-03	31	57	2	C0017658
Disease	Acute Myeloid Leukemia, M1	JAK2 NF1 WT1	1.84e-03	125	57	3	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	JAK2 NF1 WT1	1.84e-03	125	57	3	C1879321
Disease	intracranial volume measurement	DOCK4 ERBB4	1.86e-03	33	57	2	EFO_0004886

Protein segments in the cluster

Peptide	Gene	Start	Entry
VMQCILQGLDVSNMW	URB2	1246	Q14146
LNWCVQIAKGMMYLE	ERBB4	821	Q15303
QLVMQWLGQIMCTFV	ARHGEF37	411	A1IGU5
MAVCTNLLQGQMSEW	DUS3L	336	Q96G46
IFCQWQSCLQMGMYL	ASTE1	541	Q2TB18
DEIYMIMTECWNNNV	JAK2	1096	O60674
QMMILNCIYFKGSWV	SERPIND1	286	P05546
CVTMEGWTDVLYWMQ	CACNA1F	326	O60840
TMVTWVAGQEYVVNC	NPHS1	146	O60500
QMVWESGCTVIVMLT	PTPRN	796	Q16849
TCMMQAGLWAATQVS	PIP5KL1	56	Q5T9C9
VYPWMQRMNSCAGAV	HOXA6	136	P31267
AQSIVCAGMMIWNFV	GPR155	421	Q7Z3F1
YIVRMIGICEAESWM	SYK	431	P43405
QDAEYEMCVRWMQLG	MGAM	1561	O43451
WGFCNNVMMLVSDEK	EFHC2	26	Q5JST6
MVWSINLTAGMYCAA	IL13	66	P35225
MYMSCGAIVVAASVW	SLC16A7	406	O60669
VDDQMAVIQYSWMGL	AR	731	P10275
EQVMAGATLNQMLWC	PNMA2	296	Q9UL42
NDVMLSAVVMTYWTN	NLGN1	571	Q8N2Q7
MTQSQCVMLVAGSWV	OR1J1	136	Q8NGS3
MVFQQVGVSMQSVLW	MTFR1	11	Q15390
FAMLTVFQCITMEGW	CACNA1C	351	Q13936
RVTMGCEIFSMWQNL	DOCK4	1041	Q8N1I0
VTAQAMYEGLWMSCV	CLDN1	41	O95832
SMLTVYQCITMEGWT	CACNA1S	281	Q13698
MYSVCNVMSGDQDNW	EPHA2	66	P29317
YQGEDVSMGIWMAAI	B3GALNT2	436	Q8NCR0
ITWDQLGEMSYTTMC	CYP4X1	356	Q8N118
MVISWVYSVAMTIQH	ABCA2	711	Q9BZC7
EVENLAYMLVCMQWA	FADS3	281	Q9Y5Q0
VSCRMLQNTWVDTMY	DMBT1	2216	Q9UGM3
VSIMWLCTQSMLENF	SLC22A12	26	Q96S37
NDVMLSAVVMTYWTN	NLGN2	526	Q8NFZ4
IIMNGVLYVQMAAWS	OR13D1	166	Q8NGV5
AQRWMEFMVQIGCAS	SZT2	2526	Q5T011
VVWMAYMNISFHVGN	RNF133	36	Q8WVZ7
SQQCDIWSIGVVMYM	STK33	301	Q9BYT3
ITGIWTVYAMAVMNH	TMEM150A	16	Q86TG1
MVIACDGIWNVMSSQ	PPM1G	436	O15355
GNSVYEVITSWMENM	SLC3A1	421	Q07837
KEVWQESGVYTAVMM	URB1	476	O60287
VMLVSRTYCDVWMIQ	ABCD3	91	P28288
ITAQAMYKGLWMDCV	CLDN7	41	O95471
IQYMVWREMQDTLCP	TRIM69	306	Q86WT6
CMSKWEEIIYNMVVG	XKR7	351	Q5GH72
EVSGTLWQVQMHYEM	PTH1R	431	Q03431
LYQMTSQLECMTWNQ	WT1	226	P19544
MVEYLTDWVMGTSNQ	NF1	1041	P21359
FSMVNADCMSWLVQG	TGM5	396	O43548
IQCQVDSQVTMMFWY	TRBV29-1	36	A0A5B7
STTCREQMYNILMWI	PRKDC	2466	P78527
VLMFSQVISICWAAM	TMEM262	56	E9PQX1
VSMGYQHDMVLNVWD	WDR62	171	O43379
DQSYVCALIAMMVWS	PIEZO1	421	Q92508
QDMEDWMQVSKRYQC	WDR87	731	Q6ZQQ6
CWETQVGQEMYKLMI	TMC7	486	Q7Z402
MVMAWCAAVITQGQY	NDC1	126	Q9BTX1