Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B ABCC4 DDX59 ABCA12 AK9 ABCA9 ABCB1 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 TRAP1 ABCB11 MACF1 ATP2B4 DDX28

4.13e-0744119718GO:0016887
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11

4.95e-07491977GO:0140359
GeneOntologyMolecularFunctionATPase-coupled lipid transmembrane transporter activity

ABCC4 ABCA12 ABCD1 ABCB11

1.11e-0691974GO:0034040
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B ABCC4 DDX59 ABCA12 AK9 ABCA9 ABCB1 ABCD1 ASCC3 ABCD2 DYNC1H1 TTF2 RNF213 ATAD2 TRAP1 ABCB11 MACF1 ATP2B4 DDX28

1.14e-0561419719GO:0140657
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11 ATP2B4

1.26e-051091978GO:0042626
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF21B ABCC4 DDX59 ABCA12 AK9 ABCA9 ABCB1 GNA15 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 TRAP1 ENTPD6 DNM3 ABCB11 MACF1 ATP2B4 DDX28

2.83e-0577519721GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF21B ABCC4 DDX59 ABCA12 ENPP3 AK9 ABCA9 ABCB1 GNA15 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 TRAP1 ENTPD6 DNM3 ABCB11 MACF1 ATP2B4 DDX28

2.98e-0583919722GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF21B ABCC4 DDX59 ABCA12 ENPP3 AK9 ABCA9 ABCB1 GNA15 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 TRAP1 ENTPD6 DNM3 ABCB11 MACF1 ATP2B4 DDX28

3.03e-0584019722GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF21B ABCC4 DDX59 ABCA12 ENPP3 AK9 ABCA9 ABCB1 GNA15 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 TRAP1 ENTPD6 DNM3 ABCB11 MACF1 ATP2B4 DDX28

3.03e-0584019722GO:0016818
GeneOntologyMolecularFunctionlipid transporter activity

ABCC4 ABCA12 ABCA9 ABCB1 STARD3 OSBPL10 ABCD1 ABCD2 ABCB11

1.48e-041961979GO:0005319
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCC4 ABCA12 SLC35C1 ABCA9 ABCB1 ABCD1 ABCD2 SLC4A9 SLC26A5 SLC39A12 SLC20A2 ABCB11 SLC15A5 ATP2B4

2.89e-0447719714GO:0022804
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1C CACNA1D CACNA1F

3.18e-04141973GO:0008331
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC4 ABCB1 ABCB11

3.94e-04151973GO:0008559
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11 ATP2B4

3.98e-041781978GO:0015399
GeneOntologyMolecularFunctionDNA polymerase activity

REV1 POLE REV3L TEP1

5.22e-04381974GO:0034061
GeneOntologyMolecularFunctionABC-type bile acid transporter activity

ABCC4 ABCB11

5.74e-0441972GO:0015432
GeneOntologyMolecularFunctioncarnitine O-palmitoyltransferase activity

CPT1C CPT1A

5.74e-0441972GO:0004095
GeneOntologyMolecularFunctionATPase-coupled organic acid transmembrane transporter activity

ABCC4 ABCB11

5.74e-0441972GO:0033283
GeneOntologyMolecularFunctionATPase-coupled monocarboxylic acid transmembrane transporter activity

ABCC4 ABCB11

5.74e-0441972GO:0033285
GeneOntologyMolecularFunctionATPase-coupled carboxylic acid transmembrane transporter activity

ABCC4 ABCB11

5.74e-0441972GO:0033284
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

ABCC4 ABCA12 ABCD1 ABCD2 ABCB11

7.75e-04731975GO:0170055
GeneOntologyMolecularFunctionO-palmitoyltransferase activity

CPT1C CPT1A

9.50e-0451972GO:0016416
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA1D

9.50e-0451972GO:0086007
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

APEX2 ASCC3 MBD4 DNASE1L2 REV1 TTF2 POLE REV3L TEP1

1.21e-032621979GO:0140097
GeneOntologyMolecularFunctioncarnitine O-acyltransferase activity

CPT1C CPT1A

1.42e-0361972GO:0016406
GeneOntologyMolecularFunctionphosphotyrosine residue binding

PTPN6 FGR VAV1 SH2D1B

1.60e-03511974GO:0001784
GeneOntologyMolecularFunctionDNA-directed DNA polymerase activity

REV1 POLE REV3L

1.85e-03251973GO:0003887
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK11 TIAM2 VAV1 RASGRF1 ARHGEF5 RALGPS2 ARFGEF2 PLEKHG6

2.14e-032311978GO:0005085
GeneOntologyCellularComponentsomatodendritic compartment

ADCY10 TANC2 KIF21B TRPC5 SNAP47 GPR179 TIAM2 PGR PTPN6 HMCN2 CPT1C PLK3 DYNC1H1 CACNA1C CACNA1D CACNA1F RASGRF1 WFS1 ARFGEF2 SRR RET TRAK1 NDFIP1 SNX18 DNM3

1.71e-04122819325GO:0036477
GeneOntologyCellularComponentGBAF complex

BCL7C BCL7B ACTL6B

2.62e-04141933GO:0140288
GeneOntologyCellularComponentdendrite

ADCY10 TANC2 KIF21B TRPC5 SNAP47 GPR179 PGR PTPN6 CPT1C PLK3 CACNA1C CACNA1D RASGRF1 WFS1 ARFGEF2 RET TRAK1 NDFIP1 DNM3

3.90e-0485819319GO:0030425
GeneOntologyCellularComponentdendritic tree

ADCY10 TANC2 KIF21B TRPC5 SNAP47 GPR179 PGR PTPN6 CPT1C PLK3 CACNA1C CACNA1D RASGRF1 WFS1 ARFGEF2 RET TRAK1 NDFIP1 DNM3

4.02e-0486019319GO:0097447
GeneOntologyCellularComponentcalcium channel complex

TRPC5 PKD1L1 CACNA1C CACNA1D CACNA1F

5.75e-04731935GO:0034704
DomainAAA

ABCC4 ABCA12 AK9 ABCA9 ABCB1 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 ABCB11

3.52e-0814419412SM00382
DomainAAA+_ATPase

ABCC4 ABCA12 AK9 ABCA9 ABCB1 ABCD1 ASCC3 ABCD2 DYNC1H1 RNF213 ATAD2 ABCB11

3.52e-0814419412IPR003593
DomainABC_tran

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11

6.01e-07481947PF00005
DomainABC_TRANSPORTER_2

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11

6.01e-07481947PS50893
DomainABC_TRANSPORTER_1

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11

6.95e-07491947PS00211
DomainABC_transporter-like

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11

8.01e-07501947IPR003439
DomainCAC1F_C

CACNA1C CACNA1D CACNA1F

1.10e-0631943IPR031688
DomainCAC1F_C

CACNA1C CACNA1D CACNA1F

1.10e-0631943PF16885
DomainVDCC_L_a1su

CACNA1C CACNA1D CACNA1F

4.38e-0641943IPR005446
DomainABC_transporter_CS

ABCC4 ABCA12 ABCB1 ABCD1 ABCD2 ABCB11

4.47e-06421946IPR017871
DomainP-loop_NTPase

ADCY10 TANC2 KIF21B ABCC4 DDX59 ABCA12 AK9 ABCA9 ABCB1 EHD2 TRANK1 GNA15 ABCD1 ASCC3 ABCD2 DYNC1H1 NLRP8 TTF2 RNF213 TEP1 ATAD2 DNM3 ABCB11 DDX28

8.21e-0684819424IPR027417
DomainABC_TM1F

ABCC4 ABCB1 ABCD1 ABCD2 ABCB11

9.29e-06281945PS50929
DomainABC1_TM_dom

ABCC4 ABCB1 ABCD1 ABCD2 ABCB11

9.29e-06281945IPR011527
Domain-

ADCY10 ABCC4 DDX59 ABCA12 AK9 ABCA9 ABCB1 EHD2 TRANK1 GNA15 ABCD1 ASCC3 ABCD2 DYNC1H1 NLRP8 TTF2 RNF213 TEP1 ATAD2 DNM3 ABCB11 DDX28

1.07e-05746194223.40.50.300
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1F

3.75e-0571943SM01062
DomainCa_chan_IQ

CACNA1C CACNA1D CACNA1F

3.75e-0571943PF08763
DomainVDCC_a1su_IQ

CACNA1C CACNA1D CACNA1F

3.75e-0571943IPR014873
DomainGPHH

CACNA1C CACNA1D CACNA1F

3.75e-0571943PF16905
DomainGPHH_dom

CACNA1C CACNA1D CACNA1F

3.75e-0571943IPR031649
DomainLMF

LMF2 LMF1

1.07e-0421942IPR009613
DomainLMF1

LMF2 LMF1

1.07e-0421942PF06762
DomainDUF4939

RTL8B RTL8C RTL8A

1.25e-04101943IPR032549
DomainDUF4939

RTL8B RTL8C RTL8A

1.25e-04101943PF16297
DomainVDCCAlpha1

CACNA1C CACNA1D CACNA1F

1.25e-04101943IPR002077
DomainLDOC1-rel

RTL8B RTL8C RTL8A

1.71e-04111943IPR032567
DomainCPT_N

CPT1C CPT1A

3.20e-0431942IPR032476
DomainBCL_N

BCL7C BCL7B

3.20e-0431942PF04714
DomainCPT_N

CPT1C CPT1A

3.20e-0431942PF16484
DomainBCL7

BCL7C BCL7B

3.20e-0431942IPR006804
DomainDH_1

TIAM2 VAV1 RASGRF1 ARHGEF5 PLEKHG6

4.95e-04631945PS00741
DomainDNA_pol_B

POLE REV3L

6.35e-0441942PF00136
DomainABC_membrane_2

ABCD1 ABCD2

6.35e-0441942PF06472
DomainDNA-dir_DNA_pol_B

POLE REV3L

6.35e-0441942IPR006172
DomainDNA-dir_DNA_pol_B_exonuc

POLE REV3L

6.35e-0441942IPR006133
DomainDNA-dir_DNA_pol_B_multi_dom

POLE REV3L

6.35e-0441942IPR006134
DomainDNA_pol_B_exo1

POLE REV3L

6.35e-0441942PF03104
DomainPOLBc

POLE REV3L

6.35e-0441942SM00486
DomainPH

DOCK11 TIAM2 OSBPL10 VAV1 RASGRF1 ARHGEF5 PLEKHF2 RALGPS2 DNM3

6.70e-042291949PF00169
DomainPH

DOCK11 TIAM2 OSBPL10 VAV1 RASGRF1 ARHGEF5 PLEKHF2 RALGPS2 PLEKHG6 DNM3

6.77e-0427819410SM00233
DomainPH_DOMAIN

DOCK11 TIAM2 OSBPL10 VAV1 RASGRF1 ARHGEF5 PLEKHF2 RALGPS2 PLEKHG6 DNM3

6.96e-0427919410PS50003
DomainGDS_CDC24_CS

TIAM2 VAV1 RASGRF1 ARHGEF5

6.98e-04391944IPR001331
DomainRhoGEF

TIAM2 VAV1 RASGRF1 ARHGEF5 PLEKHG6

7.05e-04681945SM00325
DomainPH_domain

DOCK11 TIAM2 OSBPL10 VAV1 RASGRF1 ARHGEF5 PLEKHF2 RALGPS2 PLEKHG6 DNM3

7.16e-0428019410IPR001849
DomainRhoGEF

TIAM2 VAV1 RASGRF1 ARHGEF5 PLEKHG6

8.04e-04701945PF00621
DomainDH_2

TIAM2 VAV1 RASGRF1 ARHGEF5 PLEKHG6

8.04e-04701945PS50010
Domain-

TIAM2 VAV1 RASGRF1 ARHGEF5 PLEKHG6

8.58e-047119451.20.900.10
DomainDH-domain

TIAM2 VAV1 RASGRF1 ARHGEF5 PLEKHG6

8.58e-04711945IPR000219
DomainNACHT

NLRP11 NLRP8 TEP1

1.68e-03231943PS50837
DomainNACHT_NTPase

NLRP11 NLRP8 TEP1

1.68e-03231943IPR007111
DomainABC_membrane

ABCC4 ABCB1 ABCB11

1.90e-03241943PF00664
DomainCarn_acyl_trans

CPT1C CPT1A

2.18e-0371942IPR000542
DomainCarn_acyltransf

CPT1C CPT1A

2.18e-0371942PF00755
DomainACYLTRANSF_C_1

CPT1C CPT1A

2.18e-0371942PS00439
DomainACYLTRANSF_C_2

CPT1C CPT1A

2.18e-0371942PS00440
DomainZnf_GRF

APEX2 TTF2

2.18e-0371942IPR010666
Domainzf-GRF

APEX2 TTF2

2.18e-0371942PF06839
PathwayKEGG_ABC_TRANSPORTERS

ABCC4 ABCA12 ABCA9 ABCB1 ABCD1 ABCD2 ABCB11

3.22e-07441477M11911
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1C CACNA1D CACNA1F

2.17e-0561473M47762
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA12 ABCA9 ABCD1 ABCD2

2.43e-05171474MM14552
PathwayREACTOME_ABC_TRANSPORTERS_IN_LIPID_HOMEOSTASIS

ABCA12 ABCA9 ABCD1 ABCD2

3.10e-05181474M524
Pubmed

A low-copy repeat in Xq26 represents a novel putatively prenylated protein gene (CXX1) and its pseudogenes (DXS9914, DXS9915, and DXS9916).

RTL8B RTL8C RTL8A

1.85e-07319939403077
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HEXA TANC2 SPEG MAST2 TIAM2 GGT7 FOCAD ABCD1 PLK3 MED12 DYNC1H1 POLE ARFGEF2 FRMD8 REV3L LARS2 TEP1 TBC1D17 TRAK1 ZNF263 THADA IGF2R

4.36e-0711051992235748872
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1C CACNA1D CACNA1F

7.35e-074199320937870
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPC5 CACNA1C CACNA1D CACNA1F ATP2B4

2.51e-0638199530786075
Pubmed

RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control.

RTL8B RTL8C RTL8A

3.64e-066199335247097
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1C CACNA1D CACNA1F

6.35e-067199312900400
Pubmed

The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression.

ABCB1 ABCD1 ABCD2

6.35e-067199310504404
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TANC2 MBTD1 ABCA12 BCL7C BCL7B MAST2 DDB1 DPM1 HMCN2 ACTL6B ASCC3 VAV1 KAT5 RNF213 REV3L TEP1 THADA TNFSF13B MACF1 TOPORS

7.22e-0611161992031753913
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ACLY DPM1 GGT7 ESYT2 LMF2 CEP78 PVR ABCD1 ASCC3 DYNC1H1 TTF2 WFS1 POLE CPT1A THADA IGF2R UGGT2 ATP2B4

9.01e-069421991831073040
Pubmed

Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.

NLRP11 ABCB1 NLRP8 REV1 POLE REV3L IGF2R TNFSF13B

9.66e-06179199819074885
Pubmed

The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.

ACLY TRPC5 DDB1 ABCD1 REV3L VIRMA IGHA1 MACF1

1.93e-05197199820811636
Pubmed

Functional genomics identifies therapeutic targets for MYC-driven cancer.

SPEG BNIP2 REV1 RASGRF1 ARFGEF2 IGF2R

2.93e-05103199622623531
Pubmed

A family of neofunctionalized Ty3/gypsy retrotransposon genes in mammalian genomes.

RTL8B RTL8C RTL8A

2.94e-0511199316093683
Pubmed

Transposable elements as a source of genetic innovation: expression and evolution of a family of retrotransposon-derived neogenes in mammals.

RTL8B RTL8C RTL8A

2.94e-0511199315716091
Pubmed

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

CACNA1C CACNA1D CACNA1F

2.94e-0511199318809727
Pubmed

Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.

ABCC4 ABCB11

3.26e-052199225735837
Pubmed

Peroxisomal ATP-binding cassette transporters form mainly tetramers.

ABCD1 ABCD2

3.26e-052199228258215
Pubmed

ABCB11 and ABCB1 gene polymorphisms impact on telaprevir pharmacokinetic at one month of therapy.

ABCB1 ABCB11

3.26e-052199225661339
Pubmed

Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.

CACNA1C CACNA1D

3.26e-052199221054386
Pubmed

The role of peroxisomal ABC transporters in the mouse adrenal gland: the loss of Abcd2 (ALDR), Not Abcd1 (ALD), causes oxidative damage.

ABCD1 ABCD2

3.26e-052199217260006
Pubmed

Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.

CACNA1D CACNA1F

3.26e-052199225966695
Pubmed

Vav1 dephosphorylation by the tyrosine phosphatase SHP-1 as a mechanism for inhibition of cellular cytotoxicity.

PTPN6 VAV1

3.26e-052199212917349
Pubmed

An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.

CACNA1C CACNA1D

3.26e-052199224086669
Pubmed

Valproic acid induces antioxidant effects in X-linked adrenoleukodystrophy.

ABCD1 ABCD2

3.26e-052199220179078
Pubmed

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.

CACNA1C CACNA1D

3.26e-052199226049024
Pubmed

Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.

CACNA1C CACNA1D

3.26e-052199219225208
Pubmed

Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.

CACNA1C CACNA1D

3.26e-052199216706838
Pubmed

Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.

CACNA1C CACNA1D

3.26e-052199223761887
Pubmed

Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.

CACNA1C CACNA1D

3.26e-052199214981074
Pubmed

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.

CACNA1C CACNA1D

3.26e-052199225292336
Pubmed

Mutations in LMF1 cause combined lipase deficiency and severe hypertriglyceridemia.

LMF2 LMF1

3.26e-052199217994020
Pubmed

Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice.

ABCD1 ABCD2

3.26e-052199225255441
Pubmed

Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.

CACNA1C CACNA1D

3.26e-052199217526649
Pubmed

Sorting nexin 27 interacts with multidrug resistance-associated protein 4 (MRP4) and mediates internalization of MRP4.

ABCC4 SNX27

3.26e-052199222411990
Pubmed

ATP-binding and -hydrolysis activities of ALDP (ABCD1) and ALDRP (ABCD2), human peroxisomal ABC proteins, overexpressed in Sf21 cells.

ABCD1 ABCD2

3.26e-052199216946495
Pubmed

Ligand-activated signal transduction in the 2-cell embryo.

CACNA1C CACNA1D

3.26e-052199212606379
Pubmed

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

CACNA1C CACNA1D

3.26e-052199224941892
Pubmed

Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.

CACNA1C CACNA1D

3.26e-052199222826131
Pubmed

C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.

CACNA1D CACNA1F

3.26e-052199216921373
Pubmed

Functional overlap between ABCD1 (ALD) and ABCD2 (ALDR) transporters: a therapeutic target for X-adrenoleukodystrophy.

ABCD1 ABCD2

3.26e-052199215489218
Pubmed

Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.

CACNA1C CACNA1D

3.26e-052199224470632
Pubmed

Adrenoleukodystrophy-related protein can compensate functionally for adrenoleukodystrophy protein deficiency (X-ALD): implications for therapy.

ABCD1 ABCD2

3.26e-052199210196381
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.

CACNA1C CACNA1D

3.26e-052199224760982
Pubmed

Compensatory role of P-glycoproteins in knockout mice lacking the bile salt export pump.

ABCB1 ABCB11

3.26e-052199219650158
Pubmed

Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.

CACNA1C CACNA1D

3.26e-052199220014384
Pubmed

Coactivator assembly at the promoter: efficient recruitment of SRC2 is coupled to cooperative DNA binding by the progesterone receptor.

PGR FGR

3.26e-052199217845055
Pubmed

A key role for the peroxisomal ABCD2 transporter in fatty acid homeostasis.

ABCD1 ABCD2

3.26e-052199218854420
Pubmed

Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.

CACNA1C CACNA1D

3.26e-052199230001160
Pubmed

Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.

CACNA1C CACNA1D

3.26e-052199221352396
Pubmed

Structure-function analysis of peroxisomal ATP-binding cassette transporters using chimeric dimers.

ABCD1 ABCD2

3.26e-052199225043761
Pubmed

Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.

CACNA1C CACNA1D

3.26e-052199217409250
Pubmed

Neuronal L-type calcium channels open quickly and are inhibited slowly.

CACNA1C CACNA1D

3.26e-052199216267232
Pubmed

Influence of TS and ABCB1 gene polymorphisms on survival outcomes of 5‑FU-based chemotherapy in a Chinese population of advanced gastric cancer patients.

ABCB1 TYMS

3.26e-052199228074308
Pubmed

P-glycoprotein, but not multidrug resistance protein 4, plays a role in the systemic clearance of irinotecan and SN-38 in mice.

ABCC4 ABCB1

3.26e-052199220583968
Pubmed

The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.

CACNA1C CACNA1D

3.26e-052199224996399
Pubmed

Differential substrate specificities of human ABCD1 and ABCD2 in peroxisomal fatty acid β-oxidation.

ABCD1 ABCD2

3.26e-052199221145416
Pubmed

Silencing of Abcd1 and Abcd2 genes sensitizes astrocytes for inflammation: implication for X-adrenoleukodystrophy.

ABCD1 ABCD2

3.26e-052199218723473
Pubmed

Genetic, cellular, and functional evidence for Ca2+ inflow through Cav1.2 and Cav1.3 channels in murine spiral ganglion neurons.

CACNA1C CACNA1D

3.26e-052199224849370
Pubmed

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy.

ABCD1 ABCD2

3.26e-052199230769094
Pubmed

REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.

REV1 REV3L

3.26e-052199234508659
Pubmed

Evaluation of the role of multidrug resistance-associated protein (Mrp) 3 and Mrp4 in hepatic basolateral excretion of sulfate and glucuronide metabolites of acetaminophen, 4-methylumbelliferone, and harmol in Abcc3-/- and Abcc4-/- mice.

ABCC4 ABCB1

3.26e-052199216988054
Pubmed

Divide and conquer: an L-type voltage-gated calcium channel subtype finds a role in conditioned fear.

CACNA1C CACNA1D

3.26e-052199217015854
Pubmed

HPV-18E6 Inhibits Interactions between TANC2 and SNX27 in a PBM-Dependent Manner and Promotes Increased Cell Proliferation.

TANC2 SNX27

3.26e-052199236326272
Pubmed

Targeted Brain Delivery of Dendrimer-4-Phenylbutyrate Ameliorates Neurological Deficits in a Long-Term ABCD1-Deficient Mouse Model of X-Linked Adrenoleukodystrophy.

ABCD1 ABCD2

3.26e-052199236207570
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels regulate dopaminergic firing activity in the mouse ventral tegmental area.

CACNA1C CACNA1D

3.26e-052199224848473
Pubmed

Blood mRNA expression of REV3L and TYMS as potential predictive biomarkers from platinum-based chemotherapy plus pemetrexed in non-small cell lung cancer patients.

TYMS REV3L

3.26e-052199231832811
Pubmed

Polymorphisms in translesion polymerase genes influence treatment outcome in malignant mesothelioma.

REV1 REV3L

3.26e-052199224956248
Pubmed

LPA3 receptor mediates chemotaxis of immature murine dendritic cells to unsaturated lysophosphatidic acid (LPA).

LPAR3 ABCB1

3.26e-052199217709403
Pubmed

Cacna1c in the Prefrontal Cortex Regulates Depression-Related Behaviors via REDD1.

CACNA1C DDIT4

3.26e-052199227922594
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

ABCC4 GGT7 ESYT2 ABCD1 LNX1 TMEM181 ATRN WFS1 CPT1A IGF2R ATP2B4 GPR176

3.41e-054991991222810586
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

PGR ABCB1 TYMS ASCC3 MBD4 REV1 RET REV3L IGF2R ABCB11

3.82e-053511991020453000
Pubmed

Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.

MAOA TCEANC ABCB1 TMEM181 ADCK5 RALGPS2 CA5B

4.71e-05164199722967998
Pubmed

A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells.

BCL7C BCL7B ACTL6B

6.41e-0514199330510198
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

ABCC4 MAOA PGR ABCB1 TYMS MBD4 RET TEP1 IGF2R ABCB11

7.56e-053811991018676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

ABCC4 MAOA PGR ABCB1 TYMS MBD4 RET TEP1 IGF2R ABCB11

7.73e-053821991019170196
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1C CACNA1D CACNA1F

7.98e-0515199320188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1C CACNA1D CACNA1F

7.98e-0515199324453333
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

HEXA MAOA ACLY SPEG MIF4GD DDB1 DPM1 EHD2 ESYT2 LMF2 CPT1C PVR MAP3K10 TMEM181 LMF1 RNF213 TRAP1 IGF2R TMLHE MRPS34 UGGT2

9.64e-0514511992130550785
Pubmed

High grade glioblastoma is associated with aberrant expression of ZFP57, a protein involved in gene imprinting, and of CPT1A and CPT1C that regulate fatty acid metabolism.

CPT1C CPT1A

9.74e-053199224618825
Pubmed

Age attenuates the T-type CaV 3.2-RyR axis in vascular smooth muscle.

EHD2 CACNA1C

9.74e-053199232187825
Pubmed

ZMYND11-MBTD1 induces leukemogenesis through hijacking NuA4/TIP60 acetyltransferase complex and a PWWP-mediated chromatin association mechanism.

MBTD1 KAT5

9.74e-053199233594072
Pubmed

Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1.

REV1 REV3L

9.74e-053199220164194
Pubmed

Homo- and heterodimerization of peroxisomal ATP-binding cassette half-transporters.

ABCD1 ABCD2

9.74e-053199210551832
Pubmed

Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.

ABCD1 ABCD2

9.74e-053199225822341
Pubmed

Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).

CACNA1C CACNA1D

9.74e-053199217767505
Pubmed

FRMD8 targets both CDK4 activation and RB degradation to suppress colon cancer growth.

FRMD8 FRMD8P1

9.74e-053199237527040
Pubmed

The vital role of polymerase ζ and REV1 in mutagenic, but not correct, DNA synthesis across benzo[a]pyrene-dG and recruitment of polymerase ζ by REV1 to replication-stalled site.

REV1 REV3L

9.74e-053199222303021
Pubmed

Tumor endothelial expression of P-glycoprotein upon microvesicular transfer of TrpC5 derived from adriamycin-resistant breast cancer cells.

TRPC5 ABCB1

9.74e-053199224582564
Pubmed

Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.

CACNA1C CACNA1D

9.74e-05319922173707
Pubmed

Peroxisomal ABC Transporters: An Update.

ABCD1 ABCD2

9.74e-053199234198763
Pubmed

Suppression of c-Myc is involved in multi-walled carbon nanotubes' down-regulation of ATP-binding cassette transporters in human colon adenocarcinoma cells.

ABCC4 ABCB1

9.74e-053199225461681
Pubmed

Human ABCB1 with an ABCB11-like degenerate nucleotide binding site maintains transport activity by avoiding nucleotide occlusion.

ABCB1 ABCB11

9.74e-053199233031417
Pubmed

Live cell FRET microscopy: homo- and heterodimerization of two human peroxisomal ABC transporters, the adrenoleukodystrophy protein (ALDP, ABCD1) and PMP70 (ABCD3).

ABCD1 ABCD2

9.74e-053199217609205
Pubmed

Abcc4 together with abcb1 and abcg2 form a robust cooperative drug efflux system that restricts the brain entry of camptothecin analogues.

ABCC4 ABCB1

9.74e-053199223461902
Pubmed

G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.

CACNA1C CACNA1D

9.74e-053199226831068
Pubmed

The BCL7 gene family: deletion of BCL7B in Williams syndrome.

BCL7C BCL7B

9.74e-05319929931421
Pubmed

M. tuberculosis-Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRγ-Chain, Grb2, and SHP-1.

PTPN6 IGF2R

9.74e-053199228978467
Pubmed

Molecular cloning of complex chromosomal translocation t(8;14;12)(q24.1;q32.3;q24.1) in a Burkitt lymphoma cell line defines a new gene (BCL7A) with homology to caldesmon.

BCL7C BCL7B

9.74e-05319928605326
Pubmed

The ADAM17 sheddase complex regulator iTAP/Frmd8 modulates inflammation and tumor growth.

FRMD8 FRMD8P1

9.74e-053199236720499
Pubmed

Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.

CACNA1C CACNA1D

9.74e-053199223338940
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 TIAM2 OSBPL10 VAV1 RASGRF1 PLEKHF2 RALGPS2 PLEKHG6 DNM3

2.06e-052061329682
GeneFamilyATP binding cassette subfamily D

ABCD1 ABCD2

3.14e-0441322808
GeneFamilyDNA polymerases

REV1 POLE REV3L

6.05e-04231323535
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA1D CACNA1F

8.75e-04261323253
GeneFamilyZinc fingers GRF-type|Topoisomerases

APEX2 TTF2

1.08e-0371322135
GeneFamilyG protein-coupled receptors, Class C orphans

GPR179 GPR156

1.08e-0371322285
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

TIAM2 VAV1 RASGRF1 ARHGEF5

1.38e-03661324722
GeneFamilyATP binding cassette subfamily B

ABCB1 ABCB11

2.79e-03111322806
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

IL18RAP ZNF354C ESYT2 TRANK1 POLE RNF213 RSAD2 SH2D1B MACF1 ATP2B4

2.25e-081981991076d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY DDB1 ASCC3 DYNC1H1 CACNA1D TMPRSS6 RET REV3L MACF1

2.48e-0719519997796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID_non-vent-Lymphocytic-ILC-NK_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IL18RAP ABCB1 TRANK1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

2.94e-071991999ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

IL18RAP ABCB1 ESYT2 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

2.94e-0719919995f914962e2572b0c6372465b81b7496fa663d93c
ToppCellCOVID_non-vent-Lymphocytic-ILC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

IL18RAP ABCB1 TRANK1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

2.94e-071991999df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

IL18RAP ABCB1 ESYT2 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

2.94e-071991999e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellControl-Control-Lymphocyte-T/NK-NK|Control / Disease, condition lineage and cell class

IL18RAP ABCB1 CEP78 DDIT4 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.07e-072001999c64c27dbf4df42ca2ad2bd94b50fab87b4050ef3
ToppCellmild-NK|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL18RAP ABCB1 CEP78 DDIT4 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.07e-072001999a11fb1d7e124c352eb73fea0e0ec0fed577c97f7
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

KIF21B IL18RAP TRANK1 RNF213 RSAD2 IGF2R SH2D1B MACF1 ATP2B4

3.07e-0720019992281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL18RAP MED12 REV1 DONSON AFF2 ZNF263 PLEKHG6 SNX18

5.02e-071551998d10cf5e922dbd3ca46660404da5aca43f181fc19
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

APEX2 LMF1 RNF213 TBCCD1 THADA IGF2R FGGY DDX28

2.06e-061871998689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AK9 GGT7 CEP78 APEX2 SNX27 DYNC1H1 ARID3B TBCCD1

2.41e-061911998cadb7a9de16f4bb21606de0e25cddd2d748c7f0b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY ASCC3 DYNC1H1 CACNA1D TMPRSS6 RET REV3L MACF1

2.82e-0619519983e519cffa6144a62b06124642a14c9ff39b76554
ToppCellCOVID-19_Severe-NK|World / disease group, cell group and cell class

IL18RAP ABCB1 CEP78 DDIT4 RNF213 IGF2R SH2D1B IGHA1

2.92e-061961998f46ca7cc2d8407d0dcaa77c4b16a2c1f2a23734d
ToppCellCOVID-19_Severe-NK_activated|World / disease group, cell group and cell class

IL18RAP ABCB1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B IGHA1

3.04e-061971998a60db36d1a192998e3ded63e0c7c08d41689f95f
ToppCellhealthy_donor-Lymphocytic-ILC-NK_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.15e-061981998d7053a898e04478c577381085f615edaad3cdc5b
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP TRANK1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B MACF1

3.15e-0619819980e918e9db9b884f5328d438e90efe065e27266ee
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP TRANK1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B MACF1

3.15e-061981998ce92d5fbc2eac27fb246b044fb1914ab92506275
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL18RAP TRANK1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B MACF1

3.15e-061981998fed823d6e684d113bcc9ff3cd1803bb001aa02fa
ToppCellhealthy_donor-Lymphocytic-ILC|healthy_donor / Disease condition, Lineage, Cell class and subclass

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.15e-061981998aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCellPBMC-Severe-Lymphocyte-T/NK-NK_cell-NK_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18RAP TRANK1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B MACF1

3.15e-0619819981ef3a6bd681c223eed58300348adfef89df5563c
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-0619919984820f5bcd7bc34c2ebf6a3422cc8eb383a3b5a4e
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-061991998eb05ccae5187e4701bbbe6d714a6d2808fbcf306
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-06199199810c8729b779073c3bf808e85958d59147f0be5c5
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-061991998867fd292f3879982422e840e087bfdb3b21a8715
ToppCellMS-Multiple_Sclerosis-Lymphocyte-B-B_memory|Multiple_Sclerosis / Disease, condition lineage and cell class

EYA2 PTPN6 OSBPL10 MBD4 COL4A4 PLEKHF2 RALGPS2 IGHA1

3.27e-061991998ae2979c0d2711580863d3b751f6ff1e3abdfd90e
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-0619919985e9fe852a70546c9d235414a2c26ca3e67ba6eb9
ToppCellControl-Lymphoid_T/NK-NK|Control / Disease group, lineage and cell class

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-06199199894b2693a8378b9b2c58c6aebb2c6658d75b2e3de
ToppCellPBMC-Control-Lymphocyte-T/NK-NK_cell-NK|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL18RAP ABCB1 CEP78 RNF213 IGF2R SH2D1B MACF1 ATP2B4

3.27e-061991998d2c9fb69e5ef75778a1652da293fcf8cfa7ecfcc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR3 MAOA ABCD2 WFS1 SLC39A12 ARSF ABCB11 MACF1

3.40e-06200199807d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-NK_activated|COVID-19_Severe / Disease, condition lineage and cell class

IL18RAP TRANK1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B MACF1

3.40e-0620019986a77f9643646bafc1157bf1fc1e4c614860ee642
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CEP78 FGR FRMD8 SRR TBCCD1 IGF2R FGGY

7.85e-061601997955acb023ce4ccfac5073c9d693db87db3856187
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Interstitial_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 SPEG C17orf99 ABCA9 PTPN6 VAV1 CACNA1F

9.22e-0616419974ab1a7d5379a633c3f61af1c8c2df93b6961d9cf
ToppCellfacs-Lung-EPCAM-24m-Myeloid-lung_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TANC2 SPEG C17orf99 ABCA9 PTPN6 VAV1 CACNA1F

9.22e-0616419974e0133a7f80cf6bd3d70f72ee26360df5f80ab32
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAOA ABCA9 FSCN2 POLE SRR TEP1 RSAD2

1.12e-0516919975f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCellsevere-B_memory|World / disease stage, cell group and cell class

EYA2 PRDM2 OSBPL10 FAM227A COL4A4 RALGPS2 IGHA1

1.46e-0517619974e5c6b1aa5ffd13593a6bcd1e1253c1737c5c2b4
ToppCellmild_COVID-19_(asymptomatic)-B_memory|World / disease group, cell group and cell class (v2)

EYA2 PRDM2 OSBPL10 COL4A4 RASGRF1 RALGPS2 IGHA1

1.51e-051771997057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-B_memory-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

OSBPL10 MBD4 COL4A4 RASGRF1 PLEKHF2 RALGPS2 IGHA1

1.63e-051791997fce1ba53815145f6248d4e90aedca3dad84e33e4
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM185A C17orf99 TMEM181 LMF1 ARHGEF5 MTFP1 ATP2B4

1.75e-051811997e2d03115a87f45a7ddd3ade6b9ac3843639bd41a
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM185A C17orf99 TMEM181 LMF1 ARHGEF5 MTFP1 ATP2B4

1.75e-051811997d8d11ef83c4b8b6a6f5c8728e03059e45a8ad264
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK11 SLC35C1 MAP3K10 GNA15 FGR ATAD2 MAPK6

1.81e-05182199757f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LMF1 RNF213 TBCCD1 THADA IGF2R FGGY DDX28

2.16e-0518719974527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellMultiple_Sclerosis-Lymphocyte-B-B_memory|Multiple_Sclerosis / Disease, Lineage and Cell Type

PTPN6 OSBPL10 MBD4 COL4A4 PLEKHF2 RALGPS2 IGHA1

2.23e-0518819978da631b2c75441b7309f03e7d4c14f15f2367be6
ToppCellControl-Epithelial_alveolar-Mes-Like-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RTL8B ABCD2 CACNA1F MFSD4A TEP1 ARID3B

2.30e-051271996556aaf88719c83f307fa50dfac151136ed05c8ad
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG FZD9 COL4A4 CACNA1D ADCK5 ARHGEF5 PTCHD4

2.31e-0518919974dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG FZD9 COL4A4 CACNA1D ADCK5 ARHGEF5 PTCHD4

2.31e-0518919970d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellremission-B_memory|World / disease stage, cell group and cell class

TIAM2 PTPN6 OSBPL10 MBD4 RASGRF1 PLEKHF2 RALGPS2

2.39e-051901997c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPN6 OSBPL10 MBD4 COL4A4 PLEKHF2 RALGPS2 IGHA1

2.55e-051921997ab7420aeb22620d85c60b33cf372e5168e538cd4
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

AK9 GGT7 APEX2 SNX27 DYNC1H1 ARID3B TBCCD1

2.55e-051921997efbd52b3d2b6d3fb9ed6bc3f36aca9f4f1fcbc49
ToppCellhuman_hepatoblastoma-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MAOA CYP3A43 TMPRSS6 CPT1A PPP2R1B ABCB11 G6PC1

2.55e-051921997e785135262f4c9cc66c403bf362bb34643b212c5
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

TIAM2 PRDM2 OSBPL10 COL4A4 RALGPS2 TRAK1 IGHA1

2.64e-0519319977ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PTPN6 OSBPL10 MBD4 COL4A4 PLEKHF2 RALGPS2 IGHA1

2.73e-051941997cbc4b6422777117e4123804168c23f19d1b79486
ToppCellmLN-(1)_T_cell-(13)_Th17|mLN / shred on region, Cell_type, and subtype

IL18RAP ABCB1 GNA15 PLK3 DONSON MTFP1 TNFSF13B

3.11e-051981997c575e9aeee4e034e8c4d171fe754403652343731
ToppCellmild_COVID-19_(asymptomatic)-NK|World / disease group, cell group and cell class (v2)

ABCB1 CEP78 RNF213 EPG5 SH2D1B MACF1 ATP2B4

3.11e-0519819977a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCell390C-Lymphocytic-NK_cells|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HEXA IL18RAP PTPN6 CEP78 FGR IGF2R SH2D1B

3.11e-051981997623e5ada1a54cd42c32a1519b84dbe782384ee0c
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.11e-051981997716c27d2a37b5f865b9d191e1851917340b400af
ToppCellsevere_COVID-19-NK|World / disease group, cell group and cell class (v2)

IL18RAP ABCB1 CEP78 DDIT4 RNF213 SH2D1B IGHA1

3.11e-05198199736b1370ef68c4bbe0268933a6ef5e6022d992bdf
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.11e-051981997b12914c3c5b8dd628cb456cb40283c5016641872
ToppCellmLN-T_cell-Th17|mLN / Region, Cell class and subclass

IL18RAP ABCB1 GNA15 PLK3 DONSON MTFP1 TNFSF13B

3.11e-05198199704905f62941b193864704a10ad692faf777fa51d
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.11e-0519819971a189b2b213099505c5d871fb8aedd55a97d44e0
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-051991997e981b159841222a6838effff1059c683c20ecf5b
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-0519919978cdd5aa30a8112b77f5d02b40c45b63f541e1476
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-NK|COVID-19_Convalescent / Disease group, lineage and cell class

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-0519919979809d996a2c3f5384707646a3929e1d6b85dcdc2
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-051991997899642ff6bb6c1612f14a9a049b4344ae694752a
ToppCellControl-NK|Control / Disease condition and Cell class

IL18RAP CEP78 FGR RNF213 IGF2R SH2D1B MACF1

3.21e-051991997f3316fb97c6065286ffd22a0ad9fe7aa5b3b5650
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-051991997fd3706f256e33cf348774bea0ba0df6d41fd96e3
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell-NK-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-051991997252f0084fa17770f4c34e21066519d7f7cad75d9
ToppCellCOVID-19_Severe-Lymphoid_T/NK-NK_activated|COVID-19_Severe / Disease group, lineage and cell class

IL18RAP TRANK1 CEP78 DDIT4 RNF213 RSAD2 SH2D1B

3.21e-051991997edf5f80b4c299e6bf462675f2cd3329d86c923d8
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-NK_cell|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.21e-051991997a2ac6af5e8e13e7edd3302ebdb175a3902bfb2bc
ToppCellCOVID-19_Moderate-NK|COVID-19_Moderate / disease group, cell group and cell class

IL18RAP ABCB1 CEP78 FGR DDIT4 IGF2R SH2D1B

3.21e-051991997e0e83ba511957be9ad3413460dcb6b7d7b65dd18
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-B-B_memory|COVID-19_Convalescent / Disease, condition lineage and cell class

PTPN6 OSBPL10 MBD4 COL4A4 PLEKHF2 RALGPS2 IGHA1

3.21e-0519919975bbda86486910d053ca51b9caee487d78f6462cb
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR3 MAOA ABCD2 WFS1 SLC39A12 ABCB11 MACF1

3.31e-052001997d0812817ef99608994193787a62d39adeb2070ca
ToppCellCOVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-NK|COVID-19_Convalescent / Disease, condition lineage and cell class

IL18RAP ABCB1 CEP78 FGR DDIT4 RNF213 SH2D1B

3.31e-05200199750d844683dcfe35e59fffa0c23f1532d692d0c17
ToppCellMS-Multiple_Sclerosis-Lymphocyte-T/NK-NK_CD56bright|Multiple_Sclerosis / Disease, condition lineage and cell class

ENPP3 IL18RAP CEP78 APEX2 COL4A4 DDIT4 SH2D1B

3.31e-052001997d06bea5b4af9559a517e769a373b873cd7bdcb48
ToppCellfacs-Brain_Non-Myeloid-Hippocampus|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY DDB1 LMF2 ATRN FRMD8 LARS2 ZNF488

3.31e-052001997fc28f71ca1cd0fdae66009ae5afe175d22f2bd8c
ToppCellMS-Multiple_Sclerosis-Lymphocyte-B-B_intermediate|Multiple_Sclerosis / Disease, condition lineage and cell class

PTPN6 OSBPL10 MBD4 COL4A4 PLEKHF2 RALGPS2 IGHA1

3.31e-052001997e945dd467dc90b8042982051d1bf76b72a4baf5b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR3 MAOA ABCD2 WFS1 SLC39A12 ABCB11 MACF1

3.31e-052001997cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY10 MDGA2 POLE SLC26A5 LARS2 ABCB11

4.85e-05145199696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

DNASE1L2 SLC4A9 CACNA1C CACNA1D AFF2 LRRN4

5.43e-05148199681a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NLRP11 TYMS CACNA1F RRP9 TMLHE ATP2B4

7.02e-0515519965687416773809b8c478567bc54310af102b3029a
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GALM ABCA9 ZNF354C COL4A4 POLE MFSD4A

7.27e-0515619964877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

GALM ABCA9 ZNF354C COL4A4 POLE MFSD4A

7.27e-0515619961d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr-Polydendrocye.Tnr.Pdgfa_(Pdgfa)|Striatum / BrainAtlas - Mouse McCarroll V32

PKD1L1 PRR19 MROH2B SLC15A5 ZNF488

7.83e-0598199526250ea4171a0557a67505839cf79d3fe4d9d41a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2|Striatum / BrainAtlas - Mouse McCarroll V32

PKD1L1 PRR19 MROH2B SLC15A5 ZNF488

7.83e-059819957a62a77ca83153dacff4d02d6e32104227d0980d
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1-P1_2-Tnr|Striatum / BrainAtlas - Mouse McCarroll V32

PKD1L1 PRR19 MROH2B SLC15A5 ZNF488

7.83e-0598199542875d16ae9fcbaf988cd71be82568f2f862f2dd
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY10 ABCB1 ABCD2 FRMD8 SRR TNFSF13B

8.08e-051591996709b57f992a29878cc899d760d144d36cb5cb280
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABCC4 EYA2 TYMS DDIT4 TBCCD1 AP4E1

8.08e-051591996f7bccfeffa737f151417bf52ea45111b0957bce9
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY10 MDGA2 CACNA1C POLE LARS2 ABCB11

8.96e-051621996bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellInfluenza_Severe-B_memory|World / Disease group and Cell class

EYA2 OSBPL10 COL4A4 RALGPS2 IGHA1 GPR156

8.96e-05162199621eb96cd4fecd85dd6acbbc3760944fa1a7cff42
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

ABCC4 PLEKHF2 MFSD4A CDCP1 NDFIP1 ARSF

9.26e-051631996d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GALM MAST2 APEX2 PRR19 EPB41L5 TRAK1

9.26e-051631996ce07bc424ef99c547588b07f5c8b39ff0773ca9b
ToppCellfacs-Trachea-nan-18m-Myeloid-granulocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERV3-1 GPR63 TIAM2 PGR TRANK1 FNDC8

1.02e-0416619967f8b4cf63c3e292ae421f111edaa4572717f4db1
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 TIAM2 FGR DDIT4 WFS1 PPP2R1B

1.17e-0417019968e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDGA2 TIAM2 FGR DDIT4 WFS1 PPP2R1B

1.17e-041701996f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

ABCA12 EYA2 ATRN MFSD4A ABCB11 MAPK6

1.20e-041711996adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellILEUM-inflamed-(4)_Mast|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYCP2L ENPP3 MDGA2 TIAM2 RET MAPK6

1.24e-041721996be82f749f4b1049ae8832facc052082cf5463c11
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TYMS FAM227A TTF2 POLE ATAD2 RSAD2

1.24e-0417219967c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellILEUM-inflamed-(4)_Mast_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SYCP2L ENPP3 MDGA2 TIAM2 RET MAPK6

1.24e-0417219967185b28282412f3a464b2a8ad5605475a1a31358
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ARHGEF5 TMPRSS6 CPT1A CDCP1 LARS2

1.28e-041731996e1378201b15ffb98e196ac39fe3ee4b4078953bd
ToppCellfacs-Large_Intestine-Proximal-3m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 ARHGEF5 TMPRSS6 CPT1A CDCP1 LARS2

1.28e-04173199699532bb768ee35fed939a377acb5215d3f8904bd
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1D CACNA1F

1.01e-0641883DOID:0060173 (implicated_via_orthology)
DiseaseColorectal Neoplasms

ABCC4 ABCA12 ABCA9 ABCB1 TYMS ABCD2 DONSON POLE RET ABCB11

1.24e-0527718810C0009404
Diseasecystic fibrosis (implicated_via_orthology)

ABCC4 ABCB1 ABCB11

2.08e-0591883DOID:1485 (implicated_via_orthology)
Diseaselevel of sialic acid-binding Ig-like lectin 15 in blood serum

SIGLEC15 EPG5

4.04e-0521882OBA_2043508
DiseaseMalignant neoplasm of breast

XIRP1 DDX59 MAOA SPATA18 PGR ABCB1 TYMS LMF2 MED12 NLRP8 TMPRSS6 ARFGEF2 CPT1A EPG5 SLC39A12 RRP9 MACF1 KLHDC10 G6PC1

6.12e-05107418819C0006142
Diseaseesophageal carcinoma, gastric carcinoma

MAST2 SIGLEC15 EPG5

1.62e-04171883EFO_0000178, EFO_0002916
Diseaseurate measurement

SYCP2L CCDC81 FZD9 CPT1C COL4A4 POLE FRMD8 CPT1A AP4E1 PPP2R1B TRAP1 SLC20A2 RRP9 UGGT2 SLC14A2 G6PC1

2.11e-0489518816EFO_0004531
Diseasecholestasis (biomarker_via_orthology)

ABCC4 ABCB1 ADH5 ABCB11

2.70e-04491884DOID:13580 (biomarker_via_orthology)
DiseaseHIRSCHSPRUNG DISEASE, SUSCEPTIBILITY TO, 1

MED12 RET

5.96e-0461882C3888239
DiseaseMood Disorders

MAOA CACNA1C CACNA1D NPY2R WFS1 TNFSF13B

7.51e-041681886C0525045
Diseaseadrenoleukodystrophy (implicated_via_orthology)

ABCD1 ABCD2

8.30e-0471882DOID:10588 (implicated_via_orthology)
Diseasecolorectal cancer (implicated_via_orthology)

FGR POLE SNX18

9.10e-04301883DOID:9256 (implicated_via_orthology)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1C CACNA1D CACNA1F

1.56e-03361883DOID:11723 (implicated_via_orthology)
DiseaseDepression, Bipolar

MAOA TRANK1 CACNA1C CACNA1D

1.65e-03791884C0005587
Diseaseankyrin-2 measurement

DDX59 ATP2B4

1.76e-03101882EFO_0021874
DiseaseColorectal Carcinoma

ABCC4 ABCA12 ABCA9 ABCB1 TYMS ABCD2 NLRP8 DONSON POLE RET PPP2R1B ABCB11

1.91e-0370218812C0009402
Diseasedentate gyrus volume measurement

PKD1L1 LNX1 FGGY

1.96e-03391883EFO_0010083
DiseasePancreatic Ductal Adenocarcinoma

ABCA12 ABCD2

2.14e-03111882C1335302
DiseaseCleft palate, cleft lip

TANC2 MDGA2 GNA15 VIRMA ARID3B SLC39A12 THADA

2.16e-032791887EFO_0003959, HP_0000175
DiseaseParkinson Disease

MAOA ABCB1 DDIT4 IGF2R

2.16e-03851884C0030567
DiseaseNight blindness, congenital stationary, type 1

GPR179 CACNA1F

2.56e-03121882C3501847
DiseaseNight Blindness, Congenital Stationary, Type 1A

GPR179 CACNA1F

2.56e-03121882C3495587
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)

GPR179 CACNA1F

2.56e-03121882C1864877
DiseaseBehavior Disorders

MAOA ABCB1

2.56e-03121882C0004930
DiseaseMental disorders

MAOA ABCB1

2.56e-03121882C0004936
Diseasecollagen disease (implicated_via_orthology)

COL4A4 DNM3

2.56e-03121882DOID:854 (implicated_via_orthology)
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B

GPR179 CACNA1F

2.56e-03121882C1850362
DiseaseX-Linked Csnb

GPR179 CACNA1F

2.56e-03121882C3711543
DiseaseMental Disorders, Severe

MAOA ABCB1

2.56e-03121882C4046029
DiseaseNIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A

GPR179 CACNA1F

2.56e-03121882C1848172
DiseaseDiagnosis, Psychiatric

MAOA ABCB1

2.56e-03121882C0376338
DiseaseIschemic stroke, coronary artery disease

SPATA18 RNF213 EPG5 SLC14A2

2.88e-03921884EFO_0001645, HP_0002140
DiseaseCone-rod synaptic disorder, congenital nonprogressive

GPR179 CACNA1F

3.01e-03131882C4041558
Diseaseage at menopause

NLRP11 SYCP2L PGR ESYT2 MED12 DYNC1H1 LRRN4

3.35e-033021887EFO_0004704
Diseasetransferrin receptor protein 1 measurement

TMPRSS6 NDFIP1

3.49e-03141882EFO_0802142
DiseasePsychotic Disorders

MAOA ABCB1 MED12 CACNA1C

4.03e-031011884C0033975
Diseaseendometriosis (biomarker_via_orthology)

PGR VAV1

4.57e-03161882DOID:289 (biomarker_via_orthology)
Diseaseamygdala volume change measurement

PKD1L1 FGGY

4.57e-03161882EFO_0021490
DiseasePheochromocytoma, Extra-Adrenal

MAOA RET

4.57e-03161882C1257877
DiseaseAntibody Deficiency Syndrome

CACNA1C EPG5

5.16e-03171882C0003257
DiseaseNight blindness, congenital stationary

GPR179 CACNA1F

5.16e-03171882C0339535
Diseasealcoholic hepatitis (biomarker_via_orthology)

CPT1A ABCB11

5.78e-03181882DOID:12351 (biomarker_via_orthology)
DiseaseAdrenocortical carcinoma

ABCB1 MED12

5.78e-03181882C0206686
Diseasehepatocellular carcinoma (is_implicated_in)

ABCB1 TYMS TEP1 IGF2R G6PC1

6.19e-031811885DOID:684 (is_implicated_in)
Diseasehemoglobin A1 measurement

EYA2 MAST2 WFS1 TMPRSS6 THADA DNM3 ABCB11 MACF1 ATP2B4

6.36e-035201889EFO_0007629

Protein segments in the cluster

PeptideGeneStartEntry
TRLGFKTWLETEALP

ZNF354C

81

Q86Y25
VPLVKRLASGDWFTS

PPP2R1B

141

P30154
WREITKGLNLPTSIT

ARID3B

271

Q8IVW6
LTLTFGKLSGWVSVP

ARSF

201

P54793
IWTTGLKAPLGARVS

ERV3-1

211

Q14264
LEKFLSSSSPRAIWL

FAM227A

181

F5H4B4
FLRKPLLEINWTGLT

ESYT2

321

A0FGR8
TIPTAEFLRGSIRTW

EPG5

2281

Q9HCE0
LGLLWIIKSTPAAII

SLC4A9

896

Q96Q91
SLRVILQASPGKLLW

CA5B

6

Q9Y2D0
GKSSLFRILSGLWPV

ABCD2

516

Q9UBJ2
IATRPFQLVTGRTWK

ADH5

301

P11766
SLLPTLNRTFIWDVK

CDCP1

116

Q9H5V8
RKSLWTILLLFGISF

ABCA9

861

Q8IUA7
WSFGLPLTKDLRFDI

ABCA12

1901

Q86UK0
RKFSPWIGGSILASL

ACTL6B

386

O94805
LWVKIDLDLLSRVPG

AFF2

801

P51816
IFPLISQSRWLVKSG

ARHGEF5

1381

Q12774
LPNSVLGRIWKLSDV

EHD2

481

Q9NZN4
DIFKTTIPHVLLTWR

ARFGEF2

1476

Q9Y6D5
TKSLATGPWSLILIL

COL4A4

16

P53420
SPFLKEVLSEPWRLS

CPT1A

671

P50416
FRGWKLTLVIISVSP

ABCB11

236

O95342
LWRKVLSTAVVGAPL

ADCK5

46

Q3MIX3
WEIVGPTLKATFTTL

ATAD2

866

Q6PL18
RGVDWAPLLSTLKIN

CEP78

51

Q5JTW2
LSLPSWEKIVAGRVN

ADCY10

1576

Q96PN6
LRTSFWKSVLAGPLR

APEX2

451

Q9UBZ4
VTVGDTSLRIFKWVP

BCL7B

36

Q9BQE9
PLIVWLLVKSFSESG

DPM1

41

O60762
LWGQFISAIPTRSLK

ATP2B4

1041

P23634
IRPLKISSDDFGKLW

AP4E1

1031

Q9UPM8
SKRISFLIIGLAWGI

NPY2R

161

P49146
PLGIISFSYTRIWSK

NPY2R

231

P49146
VGFTRGWKLTLVILA

ABCB1

206

P08183
GIALLSITHRPSLWK

ABCD1

651

P33897
WERNLPSVSGLLKII

MAOA

491

P21397
LLSKGEGIRTLLWTF

CACNA1F

1306

O60840
LSGLIGVVSWKRPLS

FAM189A1

76

O60320
GVVSWKRPLSLVITF

FAM189A1

81

O60320
PRFGILLTVISWFLS

OR1S1

151

Q8NH92
LRVLPTVTWRGLKSV

IL18RAP

531

O95256
LDPWKLVSFGRTLTI

MAP3K10

896

Q02779
SLPTKVFWIAGIVKL

MBTD1

186

Q05BQ5
VWSFGILLTELITKG

FGR

441

P09769
DTSVFLLLTAVWLPK

GPR176

296

Q14439
WGFITLGRLLSIPIS

MFSD4A

356

Q8N468
TTLALIFIPKFWKLG

GPR179

621

Q6PRD1
WRQKLPGSVLLSSLL

NLRP8

306

Q86W28
ERKPSLIFLSETWSL

NLRP11

971

P59045
KLGRQWPELLLRFTS

FRMD8

96

Q9BZ67
VLGAKTFQSLRPALW

HEMK1

71

Q9Y5R4
TWRLPFDPSLKEVTI

HMCN2

231

Q8NDA2
VETIKSRLLPWLEAS

SPATA18

71

Q8TC71
STARVLWIFSPIEAK

CFAP65

1366

Q6ZU64
LTLTPWVGLRKINVS

ATRN

851

O75882
RRTLKEWTLQVSPFG

FAM185A

61

Q8N0U4
KLGRQWPELLLRFTS

FRMD8P1

96

Q9BZ68
WPLAEILSVKDISGR

KAT5

26

Q92993
LFWDIAKRVKPTGSI

DDX59

556

Q5T1V6
PSRQIVIRKGWLTIS

DNM3

521

Q9UQ16
ETLQRSWETKPGLLV

GGT7

216

Q9UJ14
RTGSLFKIWLVVPSL

KLHDC10

391

Q6PID8
GLVTKWYRSPRLLLS

MAPK6

191

Q16659
EETLPGFKWIGSRII

PGM2L1

406

Q6PCE3
LKEPRVDFWTSTIPL

CES5A

531

Q6NT32
RIWELSRFQPVGKLT

KIF21B

1436

O75037
FDTITRSAKPLEPWL

NRDE2

1021

Q9H7Z3
GLATTIIPKILAIFW

OR56B1

81

Q8NGI3
ATPGALWKALKSRLI

DDX28

261

Q9NUL7
ELKGRITLTIVSWPG

LNX1

711

Q8TBB1
GPVSKTLTVNRWFLR

LPAR3

91

Q9UBY5
VRKWTTTALGLLTIP

MTFP1

121

Q9UDX5
ERSGVWLVAPLIAKL

MED12

1421

Q93074
GPTLIAVQSSWELKR

POLE

1581

Q07864
ALFGTILELPWFKST

GNA15

256

P30679
GGSPWLLIITVFLRS

NPIPA2

56

E9PIF3
TWVRSFGTLPEKTVL

MDGA2

276

Q7Z553
IKALFLPATTEILSW

MACF1

1891

Q9UPN3
TWVTEFILLGFPLSL

OR2A5

6

Q96R48
SALFRLSEPEGKIWI

ABCC4

1086

O15439
LLSVVKWSKSLPGFR

PGR

726

P06401
DSGLTIEKSWRELVP

PLEKHG6

136

Q3KR16
SGFGLSLIKWILIVR

NDFIP1

151

Q9BT67
PTKTWLALVRIFSGR

CPT1C

146

Q8TCG5
VVGIVSWKRPFTLVI

FAM189B

81

P81408
TTKVLPAVDGSIWRL

SLC35C1

216

Q96A29
RGFDKVLWTPRVLSN

GALM

111

Q96C23
AAWGLPALKTIVILT

FZD9

361

O00144
TKIGLFFWPKITRLD

EPB41L5

261

Q9HCM4
LWSKPVSELRANFTL

C17orf99

121

Q6UX52
VTVGDTSLRIFKWVP

BCL7C

36

Q8WUZ0
KLLSRGEGIRTLLWT

CACNA1C

1386

Q13936
RLRSSEVFKWLIPDS

DNASE1L2

221

Q92874
GFAWVPLLKDGRIIT

DOCK11

756

Q5JSL3
WKRIRTLLSPAFTSV

CYP3A43

126

Q9HB55
SPSLGQTLEWLRKEL

C20orf202

31

A1L168
RKWPSSVLAFPRIEL

CCDC81

201

Q6ZN84
GSVPFEERISTLLKW

ENPP3

291

O14638
LDSRLWPKIQGLFSS

DDIT4

181

Q9NX09
LPDFLSWKATGVTAR

FGGY

171

Q96C11
GKLSKWLPFRLSSIV

G6PC1

286

P35575
VPSKWITPLDRLVAF

GET1

131

O00258
LARGFSPKDVLVRWL

IGHA1

251

P01876
LKSLIIVHPSWFIRT

BNIP2

241

Q12982
PWKLLIATIFLNRTS

MBD4

456

O95243
GITTLFTLLWAPRVF

GPR142

361

Q7Z601
WVIGSPEILRKRLSV

MAST2

896

Q6P0Q8
TELPVDWSIKTRLLF

DONSON

151

Q9NYP3
LINELVKGILPRSWS

DYNC1H1

4451

Q14204
TSLVFGPILGKSWRL

GPR156

131

Q8NFN8
PFALVTILTTRWIFG

GPR63

136

Q9BZJ6
IIAIPTGVKVFSWLA

MT-CO1

311

P00395
LWRKLFKGIPRLSVS

C20orf173

61

Q96LM9
ILPGIRGKTRLFWLL

DUOXA1

41

Q1HG43
LLKLRDSISWSPFVQ

PRSS46P

131

E5RG02
FIGTSILTPVFVRWL

SLC15A5

86

A6NIM6
VKIVASWFISPLLSG

SLC20A2

141

Q08357
KLSVSWVPLFLLLSR

SLC39A12

6

Q504Y0
KPRNWLELSVVGVSL

PKD1L1

2556

Q8TDX9
SRGEGIRTLLWTFIK

CACNA1D

1331

Q01668
WTDISARILKLPSFE

DDB1

561

Q16531
LGSKLLPAWIRIVLT

FOCAD

1251

Q5VW36
PGSFQGLTSLRKLWL

LRRC4B

246

Q9NT99
SGWIRDLPKLTSLYL

LRRN4

221

Q8WUT4
LEIIEFRAAGWKTTP

MIF4GD

196

A9UHW6
RLFPSAVDKTRIGVW

PRDM2

31

Q13029
LRNGWLIKTPTKSFA

PLEKHF2

96

Q9H8W4
GLQSAPIFRLTKTWA

RALGPS2

146

Q86X27
LSTAGVPKALSIFWL

OR52H1

81

Q8NGJ2
VPKALSIFWLGAREI

OR52H1

86

Q8NGJ2
LIGTPKRETWLQLRA

EYA2

401

O00167
DKPWGVDALLTLIFR

FSCN2

166

O14926
LVTKAGFRALLSAPW

HEXA

406

P06865
RPWIFNKILGTTVKL

FNDC8

231

Q8TC99
LTGLSTVRKPWTAVD

IGF2R

1096

P11717
GSRSVDIWLRVLAKP

PVR

131

P15151
LPLFGLGRLVTRKSW

MRPS34

71

P82930
TFLITRLTGPALQWV

RTL8A

66

Q9BWD3
TFLITRLTGPALQWV

RTL8B

66

Q17RB0
TFLITRLTGPALQWV

RTL8C

66

A6ZKI3
WLKEPIRSTGFILDG

AK9

1111

Q5TCS8
SPWTSLTRKGIVRVV

PHTF2

106

Q8N3S3
KAAILGFTSPVWAVR

THADA

1236

Q6YHU6
LAWVLPTGSFVRTKI

SIGLEC15

11

Q6ZMC9
LEPKRRWVTGQLSLT

SNAP47

61

Q5SQN1
GKLLSVFRQPLSSLW

RSAD2

11

Q8WXG1
ILWDVKTDALPGVLR

LARS2

676

Q15031
TSEIWAGLALVPRKL

LARS2

796

Q15031
FWKATPLVLKATAGL

ENTPD6

171

O75354
LKTLTLPTVWLGVAS

LMF2

361

Q9BU23
WFTSLVLRLLQGKEP

LMF2

521

Q9BU23
SDLPFFWRTSKIELT

SLC26A5

456

P58743
LERRGLTKEPVLWTL

PNPLA5

251

Q7Z6Z6
ELLSGWRRTKENLPF

PTCHD4

311

Q6ZW05
TPLFLASAVLSWKLA

SMIM15

31

Q7Z3B0
LPAFLWDKGTLTTAI

SMIM42

6

A0A5F9ZH02
IGKFPSWLKLIVTVR

TANC2

566

Q9HCD6
KSSIGLNTWPIIRDL

SRR

241

Q9GZT4
DSLASPIRWKALIAI

MROH2B

796

Q7Z745
GLKARISSWPTLVLA

RASGRF1

306

Q13972
ARSILTIPWVELGGK

OSBPL10

596

Q9BXB5
TFVWILNTDLKGRLP

STARD3

401

Q14849
PSLRWRGLKLELETF

SH2D1B

106

O14796
LTLDGVKSWLKPRLG

ACLY

76

P53396
IQGRWLKDSSLLTLP

ASCC3

1951

Q8N3C0
TSLGLVWLLKERGIS

TRAK1

736

Q9UPV9
FRVLGTKPSWIDTFI

PLA1A

91

Q53H76
TKPSWIDTFIRTLLR

PLA1A

96

Q53H76
GIVLSAVITKSWPRT

RNF213

1026

Q63HN8
TKLILSGWEPLLVTF

PLK3

591

Q9H4B4
RSKPGLSWAYLVLVT

TBC1D17

131

Q9HA65
RLSTPKLLVGDLWNL

ZNF488

206

Q96MN9
KVTVIDRGTLFLPSW

TCEANC

306

Q8N8B7
WLLSRFQKPVLGLAT

TEP1

2006

Q99973
TVSWLNPFLSLGKAR

TIAM2

1331

Q8IVF5
SWIRSGTLSPEIFEK

REV3L

1716

O60673
ATLFLRKVLSVHPWS

SPEG

3191

Q15772
PEWIVESIKAGRLLS

REV1

111

Q9UBZ9
TAFDLLKSIWLVATP

PRR19

281

A6NJB7
SVALWGLSKKRPLAL

RRP9

346

O43818
LLLVTFPISGWFALK

STOML1

66

Q9UBI4
PKFFIVGLLWLASVT

TMEM181

416

Q9P2C4
RLKGATLTAVPLWVS

SNX18

556

Q96RF0
RQGLIPKLVSWFERT

SYCP2L

106

Q5T4T6
PKLVSWFERTTGILT

SYCP2L

111

Q5T4T6
GKVIYTLSALSWTPI

VAV1

106

P15498
FPLLTTKRVFWKGVL

TYMS

71

P04818
PGTCLTIRKWLFTTE

SNX27

351

Q96L92
AKGEPWTFLVRESLS

PTPN6

126

P29350
WEKLSVRNRGFPLLT

RET

106

P07949
RILPNGEKTTRSWLL

ZMYM5

566

Q9UJ78
PFTKPALISWLEARE

ZNF445

276

P59923
ATDILPKWLRFIRGV

TRAP1

376

Q12931
LVPWLKRELTVLFGA

TOPORS

296

Q9NS56
PILTAFRLGWELKEL

TRPC5

216

Q9UL62
KVSLRTSLIGEEWPS

TBCCD1

131

Q9NVR7
VTLWIIADFDKPSGR

UGGT2

741

Q9NYU1
RAVLTPFLTKTWHSL

nan

101

Q6AWC8
RWPEVLLLLTRKVSG

TRANK1

396

O15050
VPWLLSFKRGSALEE

TNFSF13B

166

Q9Y275
LGTIFSKWDLPVFTL

SLC14A2

686

Q15849
RGAKWVTALEEIPSL

VIRMA

396

Q69YN4
PKTIRLDETTLFFTW

TMLHE

106

Q9NVH6
GDVRSTLWLFETKPL

XIRP1

376

Q702N8
SRWPGEVSFKVSRLL

TMPRSS6

641

Q8IU80
GTSTPLLRIAWARII

TTF2

721

Q9UNY4
TFVSLALRKVGDWPL

TTC31

236

Q49AM3
STILEGRLGSKWPVF

WFS1

826

O76024
VKERALSAPWLSLFP

ZNF263

186

O14978
TGTFWLTRIVLLKAL

LMF1

46

Q96S06