Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	basal part of cell	SHROOM4 ABCA1 ADRA2A NOD1 MARK2 CDH1 SLCO6A1	1.13e-04	378	61	7	GO:0045178
GeneOntologyCellularComponent	postsynaptic specialization membrane	NPTN ADRA2A DRD3 EFNB2 CHRND	3.01e-04	201	61	5	GO:0099634
GeneOntologyCellularComponent	bBAF complex	SMARCA2 SMARCA4	3.71e-04	10	61	2	GO:0140092
GeneOntologyCellularComponent	cytoplasmic side of membrane	SHROOM4 SNAPIN CDH1 ALG2 IQCE	5.56e-04	230	61	5	GO:0098562
GeneOntologyCellularComponent	basal plasma membrane	SHROOM4 ABCA1 ADRA2A NOD1 CDH1 SLCO6A1	5.73e-04	354	61	6	GO:0009925
GeneOntologyCellularComponent	npBAF complex	SMARCA2 SMARCA4	7.45e-04	14	61	2	GO:0071564
GeneOntologyCellularComponent	GBAF complex	SMARCA2 SMARCA4	7.45e-04	14	61	2	GO:0140288
GeneOntologyCellularComponent	nBAF complex	SMARCA2 SMARCA4	9.79e-04	16	61	2	GO:0071565
GeneOntologyCellularComponent	postsynaptic density membrane	NPTN ADRA2A DRD3 EFNB2	1.15e-03	157	61	4	GO:0098839
GeneOntologyCellularComponent	dopaminergic synapse	ADRA2A DRD3	1.86e-03	22	61	2	GO:0098691
Domain	HSA	SMARCA2 SMARCA4 SRCAP	1.20e-07	4	59	3	SM00573
Domain	HSA	SMARCA2 SMARCA4 SRCAP	1.20e-07	4	59	3	PS51204
Domain	HSA_dom	SMARCA2 SMARCA4 SRCAP	1.20e-07	4	59	3	IPR014012
Domain	HSA	SMARCA2 SMARCA4 SRCAP	1.20e-07	4	59	3	PF07529
Domain	SnAC	SMARCA2 SMARCA4	9.81e-06	2	59	2	SM01314
Domain	Gln-Leu-Gln_QLQ	SMARCA2 SMARCA4	9.81e-06	2	59	2	IPR014978
Domain	SnAC	SMARCA2 SMARCA4	9.81e-06	2	59	2	IPR029295
Domain	SnAC	SMARCA2 SMARCA4	9.81e-06	2	59	2	PF14619
Domain	QLQ	SMARCA2 SMARCA4	9.81e-06	2	59	2	SM00951
Domain	QLQ	SMARCA2 SMARCA4	9.81e-06	2	59	2	PS51666
Domain	QLQ	SMARCA2 SMARCA4	9.81e-06	2	59	2	PF08880
Domain	MARK/par1	MARK4 MARK2	5.86e-05	4	59	2	IPR033624
Domain	KA1_dom	MARK4 MARK2	9.75e-05	5	59	2	IPR001772
Domain	KA1	MARK4 MARK2	9.75e-05	5	59	2	PF02149
Domain	KA1	MARK4 MARK2	9.75e-05	5	59	2	PS50032
Domain	-	MARK4 MARK2	9.75e-05	5	59	2	3.30.310.80
Domain	SNF2_N	SMARCA2 SMARCA4 SRCAP	1.39e-04	32	59	3	IPR000330
Domain	SNF2_N	SMARCA2 SMARCA4 SRCAP	1.39e-04	32	59	3	PF00176
Domain	BRK	SMARCA2 SMARCA4	1.46e-04	6	59	2	SM00592
Domain	BRK_domain	SMARCA2 SMARCA4	1.46e-04	6	59	2	IPR006576
Domain	BRK	SMARCA2 SMARCA4	1.46e-04	6	59	2	PF07533
Domain	KA1/Ssp2_C	MARK4 MARK2	2.04e-04	7	59	2	IPR028375
Domain	-	ABCA1 NOD1 MOV10L1 SMARCA2 SMARCA4 KATNAL1 SRCAP RAP2C CHST7	5.17e-04	746	59	9	3.40.50.300
Domain	P-loop_NTPase	ABCA1 NOD1 MOV10L1 SMARCA2 SMARCA4 KATNAL1 SRCAP RAP2C CHST7	1.28e-03	848	59	9	IPR027417
Domain	Apc4_WD40_dom	WDHD1 WDR17	1.80e-03	20	59	2	IPR024977
Domain	ANAPC4_WD40	WDHD1 WDR17	1.80e-03	20	59	2	PF12894
Domain	Bromodomain_CS	SMARCA2 SMARCA4	3.04e-03	26	59	2	IPR018359
Domain	UBA	MARK4 MARK2	4.03e-03	30	59	2	SM00165
Domain	Helicase_C	SMARCA2 SMARCA4 SRCAP	4.71e-03	107	59	3	PF00271
Domain	HELICc	SMARCA2 SMARCA4 SRCAP	4.71e-03	107	59	3	SM00490
Domain	Helicase_C	SMARCA2 SMARCA4 SRCAP	4.83e-03	108	59	3	IPR001650
Domain	HELICASE_CTER	SMARCA2 SMARCA4 SRCAP	4.96e-03	109	59	3	PS51194
Domain	HELICASE_ATP_BIND_1	SMARCA2 SMARCA4 SRCAP	4.96e-03	109	59	3	PS51192
Domain	DEXDc	SMARCA2 SMARCA4 SRCAP	4.96e-03	109	59	3	SM00487
Domain	Helicase_ATP-bd	SMARCA2 SMARCA4 SRCAP	5.09e-03	110	59	3	IPR014001
Domain	Ion_trans_dom	CACNA1B TMEM266 KCNH3	5.62e-03	114	59	3	IPR005821
Domain	Ion_trans	CACNA1B TMEM266 KCNH3	5.62e-03	114	59	3	PF00520
Domain	UBA	MARK4 MARK2	5.77e-03	36	59	2	PF00627
Domain	BROMODOMAIN_1	SMARCA2 SMARCA4	6.09e-03	37	59	2	PS00633
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ILF2 TBC1D31 WDHD1 INPP5E SLFN12 KRR1 SRCAP GALNT7 RAP2C CDH1 GEN1 METTL14 PCNT	6.02e-08	1084	63	13	11544199
Pubmed	Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.	ABCA1 SMARCA2 SMARCA4	1.13e-07	6	63	3	15774904
Pubmed	The Pdx1-Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β-Cell Function.	SMARCA2 SMARCA4 CDH1	2.03e-06	14	63	3	31201281
Pubmed	The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.	SMARCA2 SMARCA4	3.23e-06	2	63	2	8670841
Pubmed	Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.	SMARCA2 SMARCA4	3.23e-06	2	63	2	23163725
Pubmed	Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.	SMARCA2 SMARCA4	3.23e-06	2	63	2	23076393
Pubmed	Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.	SMARCA2 SMARCA4	3.23e-06	2	63	2	9603422
Pubmed	The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.	SMARCA2 SMARCA4	3.23e-06	2	63	2	15576411
Pubmed	SWI/SNF gene variants and glioma risk and outcome.	SMARCA2 SMARCA4	3.23e-06	2	63	2	23276717
Pubmed	Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.	SMARCA2 SMARCA4	3.23e-06	2	63	2	27097303
Pubmed	Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.	SMARCA2 SMARCA4	3.23e-06	2	63	2	15240517
Pubmed	Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.	SMARCA2 SMARCA4	3.23e-06	2	63	2	26564006
Pubmed	SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.	SMARCA2 SMARCA4	3.23e-06	2	63	2	33027072
Pubmed	SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.	SMARCA2 SMARCA4	3.23e-06	2	63	2	28038711
Pubmed	A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.	SMARCA2 SMARCA4	3.23e-06	2	63	2	23872584
Pubmed	Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.	SMARCA2 SMARCA4	3.23e-06	2	63	2	23963727
Pubmed	SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.	SMARCA2 SMARCA4	3.23e-06	2	63	2	12493776
Pubmed	Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.	SMARCA2 SMARCA4	3.23e-06	2	63	2	31375262
Pubmed	Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.	SMARCA2 SMARCA4	3.23e-06	2	63	2	23088494
Pubmed	Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.	SMARCA2 SMARCA4	3.23e-06	2	63	2	17075831
Pubmed	SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.	SMARCA2 SMARCA4	3.23e-06	2	63	2	20333683
Pubmed	SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.	SMARCA2 SMARCA4	3.23e-06	2	63	2	34812766
Pubmed	Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.	SMARCA2 SMARCA4	3.23e-06	2	63	2	32855269
Pubmed	Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.	SMARCA2 SMARCA4	3.23e-06	2	63	2	30478150
Pubmed	Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.	SMARCA2 SMARCA4	3.23e-06	2	63	2	22721696
Pubmed	Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.	SMARCA2 SMARCA4	3.23e-06	2	63	2	18508913
Pubmed	Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.	SMARCA2 SMARCA4	3.23e-06	2	63	2	11719516
Pubmed	The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.	SMARCA2 SMARCA4	3.23e-06	2	63	2	25808524
Pubmed	Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.	SMARCA2 SMARCA4	3.23e-06	2	63	2	19144648
Pubmed	MARK2/4 promotes Warburg effect and cell growth in non-small cell lung carcinoma through the AMPKα1/mTOR/HIF-1α signaling pathway.	MARK4 MARK2	3.23e-06	2	63	2	35192892
Pubmed	DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.	SMARCA2 SMARCA4	3.23e-06	2	63	2	28706277
Pubmed	[Expression of BRG1 and BRM proteins in prostatic cancer].	SMARCA2 SMARCA4	3.23e-06	2	63	2	21092585
Pubmed	High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.	SMARCA2 SMARCA4	3.23e-06	2	63	2	29391527
Pubmed	Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.	SMARCA2 SMARCA4	3.23e-06	2	63	2	37634210
Pubmed	SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.	SMARCA2 SMARCA4	3.23e-06	2	63	2	26551623
Pubmed	SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.	SMARCA2 SMARCA4	3.23e-06	2	63	2	19458193
Pubmed	Brg1 inhibits E-cadherin expression in lung epithelial cells and disrupts epithelial integrity.	SMARCA4 CDH1	3.23e-06	2	63	2	28801844
Pubmed	Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.	SMARCA2 SMARCA4	3.23e-06	2	63	2	8208605
Pubmed	The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.	SMARCA2 SMARCA4	3.23e-06	2	63	2	34289068
Pubmed	SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.	SMARCA2 SMARCA4	3.23e-06	2	63	2	34518526
Pubmed	SMARCA family of genes.	SMARCA2 SMARCA4	3.23e-06	2	63	2	32312722
Pubmed	Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.	SMARCA2 SMARCA4	3.23e-06	2	63	2	26356327
Pubmed	Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.	SMARCA2 SMARCA4	3.23e-06	2	63	2	12566296
Pubmed	A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.	SMARCA2 SMARCA4	3.23e-06	2	63	2	11163203
Pubmed	Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.	SMARCA2 SMARCA4	3.23e-06	2	63	2	12620226
Pubmed	SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.	SMARCA2 SMARCA4	3.23e-06	2	63	2	31406271
Pubmed	BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.	SMARCA2 SMARCA4	3.23e-06	2	63	2	27039070
Pubmed	Partial Inactivation of the Chromatin Remodelers SMARCA2 and SMARCA4 in Virus-Infected Cells by Caspase-Mediated Cleavage.	SMARCA2 SMARCA4	3.23e-06	2	63	2	29848589
Pubmed	Co-regulation of transcription by BRG1 and BRM, two mutually exclusive SWI/SNF ATPase subunits.	SMARCA2 SMARCA4	3.23e-06	2	63	2	29273066
Pubmed	Selective Killing of SMARCA2- and SMARCA4-deficient Small Cell Carcinoma of the Ovary, Hypercalcemic Type Cells by Inhibition of EZH2: In Vitro and In Vivo Preclinical Models.	SMARCA2 SMARCA4	9.68e-06	3	63	2	28292935
Pubmed	Clinicopathological and prognostic significance of SWI/SNF complex subunits in undifferentiated gastric carcinoma.	SMARCA2 SMARCA4	9.68e-06	3	63	2	36464671
Pubmed	DNA damage sensitivity of SWI/SNF-deficient cells depends on TFIIH subunit p62/GTF2H1.	SMARCA2 SMARCA4	9.68e-06	3	63	2	30287812
Pubmed	ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1.	SMARCA4 CDH1	9.68e-06	3	63	2	20418909
Pubmed	Par-1b is required for morphogenesis and differentiation of myoepithelial cells during salivary gland development.	MARK2 CDH1	9.68e-06	3	63	2	27841695
Pubmed	Preliminary evidence for association between schizophrenia and polymorphisms in the regulatory Regions of the ADRA2A, DRD3 and SNAP-25 Genes.	ADRA2A DRD3	9.68e-06	3	63	2	22940547
Pubmed	The activity of p53 is differentially regulated by Brm- and Brg1-containing SWI/SNF chromatin remodeling complexes.	SMARCA2 SMARCA4	9.68e-06	3	63	2	17938176
Pubmed	Functional redundancy of SWI/SNF catalytic subunits in maintaining vascular endothelial cells in the adult heart.	SMARCA2 SMARCA4	9.68e-06	3	63	2	22740088
Pubmed	BRCA1 interacts with dominant negative SWI/SNF enzymes without affecting homologous recombination or radiation-induced gene activation of p21 or Mdm2.	SMARCA2 SMARCA4	9.68e-06	3	63	2	15034933
Pubmed	TopBP1 recruits Brg1/Brm to repress E2F1-induced apoptosis, a novel pRb-independent and E2F1-specific control for cell survival.	SMARCA2 SMARCA4	9.68e-06	3	63	2	15075294
Pubmed	Dopaminergic receptors and adrenoceptors in circulating lymphocytes as putative biomarkers for the early onset and progression of multiple sclerosis.	ADRA2A DRD3	9.68e-06	3	63	2	27609280
Pubmed	A putative nuclear receptor coactivator (TMF/ARA160) associates with hbrm/hSNF2 alpha and BRG-1/hSNF2 beta and localizes in the Golgi apparatus.	SMARCA2 SMARCA4	9.68e-06	3	63	2	12044884
Pubmed	SWI/SNF complexes containing Brahma or Brahma-related gene 1 play distinct roles in smooth muscle development.	SMARCA2 SMARCA4	9.68e-06	3	63	2	21518954
Pubmed	Heterogeneous SWI/SNF chromatin remodeling complexes promote expression of microphthalmia-associated transcription factor target genes in melanoma.	SMARCA2 SMARCA4	9.68e-06	3	63	2	19784067
Pubmed	Characterization of mammary tumors from Brg1 heterozygous mice.	SMARCA2 SMARCA4	9.68e-06	3	63	2	17637742
Pubmed	BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.	SMARCA2 SMARCA4	9.68e-06	3	63	2	20571081
Pubmed	Conserved SNH domain of the proto-oncoprotein SYT interacts with components of the human chromatin remodelling complexes, while the QPGY repeat domain forms homo-oligomers.	SMARCA2 SMARCA4	9.68e-06	3	63	2	14603256
Pubmed	MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.	MARK4 MARK2	9.68e-06	3	63	2	9108484
Pubmed	SWI/SNF chromatin remodeling subunit Smarca4/BRG1 is essential for female fertility†.	SMARCA2 SMARCA4	9.68e-06	3	63	2	36440965
Pubmed	Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.	SMARCA2 SMARCA4	9.68e-06	3	63	2	9099865
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	CBX6 SMARCA2 SMARCA4 SRCAP METTL14	1.00e-05	157	63	5	30186101
Pubmed	Dual role of NRSF/REST in activation and repression of the glucocorticoid response.	SMARCA2 SMARCA4	1.93e-05	4	63	2	17984088
Pubmed	Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma.	SMARCA2 SMARCA4	1.93e-05	4	63	2	31906887
Pubmed	Functional specificities of Brm and Brg-1 Swi/Snf ATPases in the feedback regulation of hepatic bile acid biosynthesis.	SMARCA2 SMARCA4	1.93e-05	4	63	2	19805516
Pubmed	SWI/SNF chromatin-remodeling enzymes Brahma-related gene 1 (BRG1) and Brahma (BRM) are dispensable in multiple models of postnatal angiogenesis but are required for vascular integrity in infant mice.	SMARCA2 SMARCA4	1.93e-05	4	63	2	25904594
Pubmed	BRM (SNF2alpha) expression is concomitant to the onset of vasculogenesis in early mouse postimplantation development.	SMARCA2 SMARCA4	1.93e-05	4	63	2	11231080
Pubmed	Modulation of nucleotide excision repair by mammalian SWI/SNF chromatin-remodeling complex.	SMARCA4 XPC	1.93e-05	4	63	2	19740755
Pubmed	BRG1/BRM and prohibitin are required for growth suppression by estrogen antagonists.	SMARCA2 SMARCA4	1.93e-05	4	63	2	15141164
Pubmed	BRG1 and BRM chromatin-remodeling complexes regulate the hypoxia response by acting as coactivators for a subset of hypoxia-inducible transcription factor target genes.	SMARCA2 SMARCA4	1.93e-05	4	63	2	23897427
Pubmed	Neuregulin-1 modulates the differentiation of neural stem cells in vitro through an interaction with the Swi/Snf complex.	SMARCA2 SMARCA4	1.93e-05	4	63	2	19781646
Pubmed	Brahma safeguards canalization of cardiac mesoderm differentiation.	SMARCA2 SMARCA4	1.93e-05	4	63	2	35082446
Pubmed	BRG1 and BRM function antagonistically with c-MYC in adult cardiomyocytes to regulate conduction and contractility.	SMARCA2 SMARCA4	1.93e-05	4	63	2	28232072
Pubmed	The clinicopathological significance of SWI/SNF alterations in gastric cancer is associated with the molecular subtypes.	SMARCA2 SMARCA4	1.93e-05	4	63	2	33481850
Pubmed	Mitotic inactivation of a human SWI/SNF chromatin remodeling complex.	SMARCA2 SMARCA4	1.93e-05	4	63	2	9744861
Pubmed	Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation.	SMARCA2 SMARCA4	1.93e-05	4	63	2	24421395
Pubmed	EphA4-ADAM10 Interplay Patterns the Cochlear Sensory Epithelium through Local Disruption of Adherens Junctions.	EFNB2 CDH1	1.93e-05	4	63	2	30639848
Pubmed	Mammalian chromatin remodeling complex SWI/SNF is essential for enhanced expression of the albumin gene during liver development.	SMARCA2 SMARCA4	1.93e-05	4	63	2	16452305
Pubmed	Control of B cell development by the histone H2A deubiquitinase MYSM1.	SMARCA2 SMARCA4	1.93e-05	4	63	2	22169041
Pubmed	STK11 is required for the normal program of ciliated cell differentiation in airways.	MARK4 MARK2 CDH1	2.46e-05	31	63	3	31636950
Pubmed	Prohibitin and the SWI/SNF ATPase subunit BRG1 are required for effective androgen antagonist-mediated transcriptional repression of androgen receptor-regulated genes.	SMARCA2 SMARCA4	3.22e-05	5	63	2	18487222
Pubmed	Altered control of cellular proliferation in the absence of mammalian brahma (SNF2alpha).	SMARCA2 SMARCA4	3.22e-05	5	63	2	9843504
Pubmed	The SWI/SNF chromatin remodeling complex regulates myocardin-induced smooth muscle-specific gene expression.	SMARCA2 SMARCA4	3.22e-05	5	63	2	19342595
Pubmed	Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.	SMARCA2 SMARCA4	3.22e-05	5	63	2	12200431
Pubmed	Dynamic recruitment of functionally distinct Swi/Snf chromatin remodeling complexes modulates Pdx1 activity in islet β cells.	SMARCA2 SMARCA4	3.22e-05	5	63	2	25801033
Pubmed	Interaction of HP1 and Brg1/Brm with the globular domain of histone H3 is required for HP1-mediated repression.	SMARCA2 SMARCA4	3.22e-05	5	63	2	20011120
Pubmed	Prohibitin requires Brg-1 and Brm for the repression of E2F and cell growth.	SMARCA2 SMARCA4	3.22e-05	5	63	2	12065415
Pubmed	Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.	MARK4 MARK2	4.82e-05	6	63	2	23666762
Pubmed	A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.	SMARCA2 SMARCA4	4.82e-05	6	63	2	10619021
Pubmed	Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex.	SMARCA2 SMARCA4	4.82e-05	6	63	2	16940996
Pubmed	Deletion of Inpp5a causes ataxia and cerebellar degeneration in mice.	INPP5E PCNT	4.82e-05	6	63	2	26051944
Pubmed	Asynchrony of Apical Polarization, Luminogenesis, and Functional Differentiation in the Developing Thyroid Gland.	CDH1 PCNT	4.82e-05	6	63	2	34975747
Coexpression	GSE36009_UNSTIM_VS_LPS_STIM_DC_UP	IL10RA NOD1 WDHD1 SLFN12 RAP2C DOP1A	7.89e-06	200	62	6	M8778
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	SNAPIN NOD1 FAM13C INPP5E GNPTAB SMARCA2 KATNAL1 CPT1A SRCAP FMNL2 GEN1 IQCE	8.88e-06	1102	62	12	M2369
Coexpression	GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN	SNAPIN NOD1 FAM13C INPP5E GNPTAB SMARCA2 KATNAL1 CPT1A SRCAP FMNL2 GEN1 IQCE	1.08e-05	1124	62	12	MM1070
Disease	Schizophrenia	IL10RA CACNA1B NPTN ABCA1 ADRA2A DRD3 EFNB2 SMARCA2 MARK2 PCNT	1.44e-05	883	62	10	C0036341
Disease	visual impairment and progressive phthisis bulbi (implicated_via_orthology)	MARK4 MARK2	2.60e-05	4	62	2	DOID:0070356 (implicated_via_orthology)
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	SMARCA2 SMARCA4	4.33e-05	5	62	2	C3281201
Disease	Adenoid Cystic Carcinoma	SMARCA2 MARK2 SRCAP CDH1	5.96e-05	100	62	4	C0010606
Disease	opportunistic bacterial infectious disease (implicated_via_orthology)	SMARCA2 SMARCA4	1.55e-04	9	62	2	DOID:0050340 (implicated_via_orthology)
Disease	free cholesterol to total lipids in small HDL percentage	ABCA1 SMARCA4 CPT1A	1.71e-04	51	62	3	EFO_0022285
Disease	obesity (biomarker_via_orthology)	ABCA1 INPP5E CPT1A ITIH4	2.64e-04	147	62	4	DOID:9970 (biomarker_via_orthology)
Disease	atrophic macular degeneration, age-related macular degeneration, wet macular degeneration	ABCA1 MARK4 ACAD10	2.78e-04	60	62	3	EFO_0001365, EFO_0004683, EFO_1001492
Disease	Coffin-Siris syndrome	SMARCA2 SMARCA4	3.34e-04	13	62	2	C0265338
Disease	Myasthenic Syndromes, Congenital, Slow Channel	ALG2 CHRND	5.11e-04	16	62	2	C0751885
Disease	Congenital Myasthenic Syndromes, Postsynaptic	ALG2 CHRND	5.79e-04	17	62	2	C0751883
Disease	Congenital Myasthenic Syndromes, Presynaptic	ALG2 CHRND	7.26e-04	19	62	2	C0751884
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	SMARCA4 CDH1	7.26e-04	19	62	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	SMARCA4 CDH1	7.26e-04	19	62	2	C2936783
Disease	alcohol use disorder (implicated_via_orthology)	DRD3 SMARCA2 SMARCA4 CHRND	7.65e-04	195	62	4	DOID:1574 (implicated_via_orthology)
Disease	Myasthenic Syndromes, Congenital	ALG2 CHRND	1.16e-03	24	62	2	C0751882
Disease	level of Sterol ester (27:1/18:2) in blood serum	MARK4 SMARCA4	1.37e-03	26	62	2	OBA_2045194
Disease	Hereditary Nonpolyposis Colorectal Neoplasms	SMARCA4 CDH1	1.37e-03	26	62	2	C0009405
Disease	Hereditary non-polyposis colorectal cancer syndrome	SMARCA4 CDH1	1.47e-03	27	62	2	C1112155
Disease	Movement Disorders	CACNA1B DRD3	1.70e-03	29	62	2	C0026650
Disease	Hereditary Nonpolyposis Colorectal Cancer	SMARCA4 CDH1	1.70e-03	29	62	2	C1333990
Disease	Ovarian Carcinoma	SMARCA4 CDH1	1.82e-03	30	62	2	C0029925
Disease	Breast Cancer, Familial	CDH1 GEN1	1.82e-03	30	62	2	C0346153
Disease	omega-3 polyunsaturated fatty acid measurement	ABCA1 SMARCA4 CPT1A	1.99e-03	118	62	3	EFO_0010119

Protein segments in the cluster

Peptide	Gene	Start	Entry
IIRRKPLFYIINILV	CHRND	241	Q07001
IIKRRIRKGRIEYLV	CBX6	16	O95503
ILEIKELTKIYRRKR	ABCA1	1911	O95477
LYRRKLDREEIKPIR	CPT1A	281	P50416
YIRLANRDLVLRKKP	ACAD10	301	Q6JQN1
REFKPYVVRLAKLLR	DOP1A	2346	Q5JWR5
RVLRVLRPLKTIKRL	CACNA1B	1251	Q00975
KRRLGVYELLLKVRP	ITIH4	151	Q14624
VRVKRYEKVPLILVG	RAP2C	101	Q9Y3L5
LPTKRVRFGLKLYVL	PGBD4	266	Q96DM1
RFKRRVLIQYLEKVL	INTS6L	826	Q5JSJ4
KPRLLRRIVELEKKL	IQCE	336	Q6IPM2
YSLRPRREEVKLKEI	LBR	166	Q14739
LRDYIRIHRIPKPLK	KCNH3	521	Q9ULD8
LQALELLLIRKYIPR	PM20D1	166	Q6GTS8
QRIPRYELLVKDLLK	ARHGEF17	1211	Q96PE2
LKERAIYVLVRIIKG	C22orf15	71	Q8WYQ4
ITPYRKQVEKIRILL	MOV10L1	1066	Q9BXT6
ITQYLIRIRKLTLKR	MAK16	116	Q9BXY0
QLIALKRKIFPRRRI	GNPTAB	1231	Q3T906
RELYLLGIKRRISKE	INPP5E	611	Q9NRR6
YPKLRELIRLKDELI	METTL14	146	Q9HCE5
RYPGIVKKLLRRLSQ	ARSJ	511	Q5FYB0
IIITLVVLLLKYRRR	EFNB2	241	P52799
IEVPRQFLRKKVLLR	NOD1	336	Q9Y239
YIIIRARDLIKLLAR	KRR1	111	Q13601
LQLYVRRRKKLPSVL	IL10RA	256	Q13651
RVVIAILRLRFLVKK	PCNT	3201	O95613
RFLKIIRPLRNIFLK	P2RY13	141	Q9BPV8
KLARIEEPKRVLLYV	GRHL1	521	Q9NZI5
EKPKEYLISLLERLR	EFCAB10	36	A6NFE3
KRVPSIYKLKLRPRI	GAS2L2	766	Q8NHY3
IKRTPRKYLAEIVLI	GALNT7	231	Q86SF2
KVLIRLLKDLRIRFP	ILF2	221	Q12905
VKVLRLYERERKPLE	FMNL2	746	Q96PY5
HVTLLIYRRLRKPKI	LY9	351	Q9HBG7
KELRERVLRGKYRIP	MARK2	256	Q7KZI7
LKELRERVLRGKYRV	MARK4	261	Q96L34
KLVKVIRYQRPDLLL	GEN1	341	Q17RS7
LLLLFLRRRAVVKEP	CDH1	726	P12830
IYVVLKQRRRKRILT	DRD3	211	P35462
VKERIIPYLLRLRQI	PNPLA8	401	Q9NP80
EALRRRLEKRIYIPL	KATNAL1	366	Q9BW62
YVKKLLNARRRVVLV	SNAPIN	81	O95295
YPIKSRKLLRVLQRT	TBC1D31	466	Q96DN5
VLRPFLLRRLKKEVE	SMARCA2	941	P51531
LLYVILIPRKLCIKL	OR5AL1	146	P0C617
VLRPFLLRRLKKEVE	SMARCA4	971	P51532
LIKGSFRILKLIVRR	SHROOM4	76	Q9ULL8
KKHRYLRLLPEALIR	SLCO6A1	46	Q86UG4
ELKARKIPIIIRRYL	POLR2F	96	P61218
LLKRREVSVPLKIEY	WDR17	1191	Q8IZU2
IKPLYDRYRIIKQIL	FAM13C	421	Q8NE31
KVLRPFLLRRVKVDV	SRCAP	831	Q6ZRS2
YNLKRTPRRIKAIII	ADRA2A	156	P08913
IPVFRLARRRKKILF	ALG2	121	Q9H553
CRKYPVVVIKDVRLL	CHST7	241	Q9NS84
LSLYRIRKPDQVKLR	ZSWIM5	251	Q9P217
LLAIPVEKSVKLYRR	WDHD1	201	O75717
IILVVIIVVYEKRKR	NPTN	351	Q9Y639
KTRGRLYLRPELLAK	SLFN12	151	Q8IYM2
LAKGLLIRERLKRRY	XPC	851	Q01831
RVKRVIDAYVLPVKL	TMEM266	211	Q2M3C6