Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF729 RLF ZNF717 ZNF556 ZNF341 ZNF43 TP63 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

7.42e-0914127622GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF729 ZNF717 BPTF ZNF556 ZNF341 ZNF43 TP63 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

1.35e-0814597622GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF729 ZNF717 BPTF ZNF341 ZNF43 TP63 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

2.54e-0812447620GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF729 ZNF717 BPTF ZNF341 ZNF43 TP63 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

3.63e-0812717620GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

ZNF729 RLF ZNF717 ZNF341 ZNF43 TP63 ZNF521 ZNF226 ZNF319 ZNF681 ZFY ZIC3

1.42e-065667612GO:0001216
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

ZNF729 RLF ZNF717 ZNF43 TP63 ZNF521 ZNF226 ZNF319 ZNF681 ZFY ZIC3

8.42e-065607611GO:0001228
GeneOntologyMolecularFunctionthioesterase binding

TRAF3 TRAF5

6.31e-0410762GO:0031996
Domain-

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

1.52e-1267975203.30.160.60
DomainZINC_FINGER_C2H2_2

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF804B ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

1.84e-127757521PS50157
DomainZINC_FINGER_C2H2_1

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF804B ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

1.93e-127777521PS00028
Domainzf-C2H2

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

2.20e-126937520PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

2.26e-126947520IPR013087
DomainZnf_C2H2-like

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF804B ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

3.06e-127967521IPR015880
DomainZnf_C2H2

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF804B ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

3.79e-128057521IPR007087
DomainZnF_C2H2

ZNF729 RLF ZNF556 ZNF341 ZNF43 ZNF804B ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

4.07e-128087521SM00355
Domainzf-C2H2_6

ZNF729 ZNF556 ZNF43 ZNF813 ZNF521 ZNF571 ZNF90 ZNF626 ZNF791 ZNF426 ZNF681 ZNF114 PRDM1

3.33e-103147513PF13912
DomainKRAB

ZNF729 ZNF556 ZNF43 ZNF813 ZNF571 ZNF226 ZNF90 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZNF114

1.65e-093587513PS50805
DomainKRAB

ZNF729 ZNF556 ZNF43 ZNF813 ZNF571 ZNF226 ZNF90 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZNF114

1.65e-093587513PF01352
DomainKRAB

ZNF729 ZNF556 ZNF43 ZNF813 ZNF571 ZNF226 ZNF90 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZNF114

2.37e-093697513SM00349
DomainKRAB

ZNF729 ZNF556 ZNF43 ZNF813 ZNF571 ZNF226 ZNF90 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZNF114

2.45e-093707513IPR001909
Domain-

RNF121 PHF2 BPTF TRAF3 TRAF5 ZNF341 FGD4 MKRN1 ZNF521 RNF175

1.20e-0544975103.30.40.10
DomainZnf_RING/FYVE/PHD

RNF121 PHF2 BPTF TRAF3 TRAF5 ZNF341 FGD4 MKRN1 ZNF521 RNF175

1.45e-054597510IPR013083
DomainArp3_met

ACTR3C ACTR3B

4.76e-053752IPR015623
DomainZF_DAG_PE_1

PRKD3 MYO9A CHN2 UNC13A

1.27e-0464754PS00479
DomainZF_DAG_PE_2

PRKD3 MYO9A CHN2 UNC13A

1.27e-0464754PS50081
DomainC1

PRKD3 MYO9A CHN2 UNC13A

1.35e-0465754SM00109
DomainPE/DAG-bd

PRKD3 MYO9A CHN2 UNC13A

1.43e-0466754IPR002219
DomainTNF_rcpt--assoc_TRAF

TRAF3 TRAF5

2.36e-046752IPR012227
Domainzf-TRAF

TRAF3 TRAF5

4.39e-048752PF02176
DomainMATH/TRAF_dom

TRAF3 TRAF5

1.02e-0312752IPR002083
DomainMATH

TRAF3 TRAF5

1.02e-0312752PS50144
DomainMATH

TRAF3 TRAF5

1.02e-0312752SM00061
DomainZnf_TRAF

TRAF3 TRAF5

1.02e-0312752IPR001293
DomainMATH

TRAF3 TRAF5

1.02e-0312752PF00917
DomainZF_TRAF

TRAF3 TRAF5

1.21e-0313752PS50145
Domain-

TRAF3 TRAF5

1.40e-03147523.90.890.10
Domain-

TRAF3 TRAF5

1.40e-03147522.60.210.10
DomainC1_1

PRKD3 CHN2 UNC13A

1.56e-0357753PF00130
DomainSIAH-type

TRAF3 TRAF5

1.84e-0316752IPR013323
DomainFrizzled/SFRP

SFRP4 FRZB

1.84e-0316752IPR015526
DomainC345C

SFRP4 FRZB

2.08e-0317752SM00643
DomainNTR

SFRP4 FRZB

2.60e-0319752PF01759
DomainNetrin_module_non-TIMP

SFRP4 FRZB

2.60e-0319752IPR018933
DomainACTINS_ACT_LIKE

ACTR3C ACTR3B

2.60e-0319752PS01132
DomainFRI

SFRP4 FRZB

2.88e-0320752SM00063
DomainDAG/PE-bd

PRKD3 CHN2

3.18e-0321752IPR020454
Domain-

SFRP4 FRZB

3.18e-03217521.10.2000.10
Domainzf-DHHC

ZDHHC20 ZDHHC16

3.81e-0323752PF01529
DomainNTR

SFRP4 FRZB

3.81e-0323752PS50189
DomainNetrin_domain

SFRP4 FRZB

3.81e-0323752IPR001134
DomainFrizzled_dom

SFRP4 FRZB

4.15e-0324752IPR020067
DomainFZ

SFRP4 FRZB

4.15e-0324752PS50038
DomainFz

SFRP4 FRZB

4.15e-0324752PF01392
DomainTRAF-like

TRAF3 TRAF5

4.15e-0324752IPR008974
DomainDHHC

ZDHHC20 ZDHHC16

4.50e-0325752PS50216
DomainZnf_DHHC_palmitoyltrfase

ZDHHC20 ZDHHC16

4.50e-0325752IPR001594
DomainTIMP-like_OB-fold

SFRP4 FRZB

4.86e-0326752IPR008993
DomainZF_RING_1

RNF121 TRAF3 TRAF5 MKRN1 RNF175

6.30e-03291755PS00518
DomainActin

ACTR3C ACTR3B

6.86e-0331752IPR004000
DomainActin

ACTR3C ACTR3B

6.86e-0331752PF00022
DomainACTIN

ACTR3C ACTR3B

6.86e-0331752SM00268
DomainZF_RING_2

RNF121 TRAF3 TRAF5 MKRN1 RNF175

6.95e-03298755PS50089
DomainRING

RNF121 TRAF3 TRAF5 MKRN1 RNF175

7.64e-03305755SM00184
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

ZNF729 ZNF717 SETD1A ZNF556 ZNF43 TP63 ZNF804B ZNF521 ZNF571 ZNF226 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZNF114 PRDM1

2.88e-0613875017M734
PathwayKEGG_MEDICUS_PATHOGEN_EBV_LMP1_TO_PI3K_SIGNALING_PATHWAY

TRAF3 TRAF5

1.22e-045502M49020
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF729 PHF2 BPTF ZDHHC20 ZNF43 MKRN1 ZDHHC16 ZNF626 ZNF426 CRIP2 ZNF681 PRDM1

1.81e-07808761220412781
Pubmed

Regulator of sex-limitation (Rsl) encodes a pair of KRAB zinc-finger genes that control sexually dimorphic liver gene expression.

ZNF729 ZNF43 ZNF626 ZNF681

4.80e-072976414563677
Pubmed

Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.

ZNF813 ZNF90 ZNF626 ZNF791 ZNF583 ZNF681

2.96e-0618176637372979
Pubmed

Expansion and diversification of KRAB zinc-finger genes within a cluster including Regulator of sex-limitation 1 and 2.

ZNF729 ZNF43 ZNF681

4.48e-061576315885501
Pubmed

Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expression.

SFRP4 FRZB

4.71e-06276210728394
Pubmed

Up-regulation and pre-activation of TRAF3 and TRAF5 in inflammatory bowel disease.

TRAF3 TRAF5

4.71e-06276223329887
Pubmed

Single amino acid substitutions confer the antiviral activity of the TRAF3 adaptor protein onto TRAF5.

TRAF3 TRAF5

4.71e-06276223150880
Pubmed

Transcriptional activity of the promoter region of rat frizzled-related protein gene.

SFRP4 FRZB

4.71e-06276211485313
Pubmed

Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma.

ACTR3C ACTR3B

4.71e-06276211162478
Pubmed

Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis.

SFRP4 FRZB

4.71e-06276239425025
Pubmed

Association between polymorphisms in sclerostin, dickkopfs and secreted frizzled-related protein genes and bone mineral density in postmenopausal Korean women.

SFRP4 FRZB

4.71e-06276224662300
Pubmed

Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells.

ACTR3C ACTR3B

4.71e-06276214651955
Pubmed

Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.

ZNF43 ZNF90 ZNF114

5.50e-06167638467795
Pubmed

Retinoic acid-inducible gene-I-like receptor (RLR)-mediated antiviral innate immune responses in the lower respiratory tract: Roles of TRAF3 and TRAF5.

TRAF3 TRAF5

1.41e-05376226454171
Pubmed

DeltaNp63/BMP-7-dependent expression of matrilin-2 is involved in keratinocyte migration in response to wounding.

TP63 MATN2

1.41e-05376218328806
Pubmed

TNF receptor (TNFR)-associated factor (TRAF) 3 serves as an inhibitor of TRAF2/5-mediated activation of the noncanonical NF-kappaB pathway by TRAF-binding TNFRs.

TRAF3 TRAF5

2.82e-05476215708970
Pubmed

TRAF5, an activator of NF-kappaB and putative signal transducer for the lymphotoxin-beta receptor.

TRAF3 TRAF5

2.82e-0547628663299
Pubmed

A genome-wide association study identifies two new susceptibility loci for lung adenocarcinoma in the Japanese population.

BPTF TP63

2.82e-05476222797724
Pubmed

CD27, a member of the tumor necrosis factor receptor superfamily, activates NF-kappaB and stress-activated protein kinase/c-Jun N-terminal kinase via TRAF2, TRAF5, and NF-kappaB-inducing kinase.

TRAF3 TRAF5

2.82e-0547629582383
Pubmed

Differential effects of secreted frizzled-related proteins (sFRPs) on osteoblastic differentiation of mouse mesenchymal cells and apoptosis of osteoblasts.

SFRP4 FRZB

2.82e-05476218166153
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

BPTF MYO9A DUSP5 CNPY3 SPEN ZMYM4 ZNF114

3.80e-0542076728065597
Pubmed

Deterministic and stochastic allele specific gene expression in single mouse blastomeres.

FRZB MKRN1 PDGFC ZFY ZIC3 JAM2 PRDM1

4.04e-0542476721731673
Pubmed

Setd1a and NURF mediate chromatin dynamics and gene regulation during erythroid lineage commitment and differentiation.

BPTF SETD1A

4.69e-05576227141965
Pubmed

Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3.

HIPK3 SPEN

4.69e-05576220484411
Pubmed

TRAF-1, -2, -3, -5, and -6 are induced in atherosclerotic plaques and differentially mediate proinflammatory functions of CD40L in endothelial cells.

TRAF3 TRAF5

4.69e-05576217332487
Pubmed

Comparison of the peptide binding preferences of three closely related TRAF paralogs: TRAF2, TRAF3, and TRAF5.

TRAF3 TRAF5

4.69e-05576226779844
Pubmed

Lymphotoxin beta receptor induces interleukin 8 gene expression via NF-kappaB and AP-1 activation.

TRAF3 TRAF5

4.69e-05576212169272
Pubmed

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling.

TRAF3 TRAF5

4.69e-05576229661858
Pubmed

Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1).

TRAF3 TRAF5

4.69e-05576210523862
Pubmed

Two differently regulated nuclear factor kappaB activation pathways triggered by the cytoplasmic tail of CD40.

TRAF3 TRAF5

4.69e-0557629990007
Pubmed

TAJ, a novel member of the tumor necrosis factor receptor family, activates the c-Jun N-terminal kinase pathway and mediates caspase-independent cell death.

TRAF3 TRAF5

4.69e-05576210809768
Pubmed

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency.

ZIC3 JAM2 PRDM1

5.71e-053476320007774
Pubmed

Human transcription factor protein interaction networks.

RLF PHF2 BPTF SETD1A TRAF3 DCP1B ZNF521 ZNF319 SPEN ZMYM4 ZIC3 PRDM1

6.01e-051429761235140242
Pubmed

The TNF-receptor-associated factor family: scaffold molecules for cytokine receptors, kinases and their regulators.

TRAF3 TRAF5

7.03e-05676211384837
Pubmed

Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling.

TRAF3 TRAF5

7.03e-05676221041727
Pubmed

Tumor necrosis factor receptor-associated factor (TRAF)2 represses the T helper cell type 2 response through interaction with NFAT-interacting protein (NIP45).

TRAF3 TRAF5

7.03e-05676211435475
Pubmed

Ubiquitin ligase Smurf1 targets TRAF family proteins for ubiquitination and degradation.

TRAF3 TRAF5

7.03e-05676219937093
Pubmed

Receptor activator of NF-kappaB recruits multiple TRAF family adaptors and activates c-Jun N-terminal kinase.

TRAF3 TRAF5

7.03e-05676210025951
Pubmed

Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation.

TRAF3 TRAF5

7.03e-0567629488716
Pubmed

Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2.

TRAF3 TRAF5

7.03e-0567629275204
Pubmed

BS69 cooperates with TRAF3 in the regulation of Epstein-Barr virus-derived LMP1/CTAR1-induced NF-kappaB activation.

TRAF3 TRAF5

7.03e-05676220138174
Pubmed

The involvement of multiple tumor necrosis factor receptor (TNFR)-associated factors in the signaling mechanisms of receptor activator of NF-kappaB, a member of the TNFR superfamily.

TRAF3 TRAF5

7.03e-0567629852070
Pubmed

TRAF3 forms heterotrimers with TRAF2 and modulates its ability to mediate NF-{kappa}B activation.

TRAF3 TRAF5

7.03e-05676215383523
Pubmed

Wnt3a binds to several sFRPs in the nanomolar range.

SFRP4 FRZB

7.03e-05676217462603
Pubmed

Structurally distinct recognition motifs in lymphotoxin-beta receptor and CD40 for tumor necrosis factor receptor-associated factor (TRAF)-mediated signaling.

TRAF3 TRAF5

7.03e-05676214517219
Pubmed

The lymphotoxin-beta receptor is necessary and sufficient for LIGHT-mediated apoptosis of tumor cells.

TRAF3 TRAF5

7.03e-05676210799510
Pubmed

Tumor necrosis factor receptor-associated factors (TRAFs).

TRAF3 TRAF5

7.03e-05676211607847
Pubmed

Role of NF kappa B activator Act1 in CD40-mediated signaling in epithelial cells.

TRAF3 TRAF5

7.03e-05676212089335
Pubmed

BAG6 negatively regulates the RLR signaling pathway by targeting VISA/MAVS.

TRAF3 TRAF5

7.03e-05676236045679
Pubmed

Hepatitis B Virus-Induced Parkin-Dependent Recruitment of Linear Ubiquitin Assembly Complex (LUBAC) to Mitochondria and Attenuation of Innate Immunity.

TRAF3 TRAF5

9.83e-05776227348524
Pubmed

Molecular characterization of CD40 signaling intermediates.

TRAF3 TRAF5

9.83e-05776211562359
Pubmed

Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB and AP-1.

TRAF3 TRAF5

9.83e-0577629162022
Pubmed

The expression and the regulatory role of OX40 and 4-1BB heterodimer in activated human T cells.

TRAF3 TRAF5

9.83e-05776215941918
Pubmed

The TRAF family of signal transducers mediates NF-kappaB activation by the TRANCE receptor.

TRAF3 TRAF5

9.83e-0577629774460
Pubmed

CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization.

TRAF3 TRAF5

9.83e-0577629718306
Pubmed

SNX5 inhibits RLR-mediated antiviral signaling by targeting RIG-I-VISA signalosome.

TRAF3 TRAF5

9.83e-05776231806368
Pubmed

Interaction network of human early embryonic transcription factors.

RLF BPTF SETD1A ZNF521 SPEN ZMYM4

1.22e-0435176638297188
Pubmed

Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

BPTF TP63

1.31e-04876223143601
Pubmed

ASK1 is essential for JNK/SAPK activation by TRAF2.

TRAF3 TRAF5

1.31e-0487629774977
Pubmed

CD40-mediated tumor necrosis factor receptor-associated factor 3 signaling upregulates IL-4-induced germline Cepsilon transcription in a human B cell line.

TRAF3 TRAF5

1.31e-04876212220533
Pubmed

The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins.

ZNF43 ZNF90

1.31e-0487622023909
Pubmed

WNK1 kinase balances T cell adhesion versus migration in vivo.

OXSR1 CCL21

1.31e-04876227400149
Pubmed

USP7-Dependent Regulation of TRAF Activation and Signaling by a Viral Interferon Regulatory Factor Homologue.

TRAF3 TRAF5

1.31e-04876231666375
Pubmed

TTRAP, a novel protein that associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor-associated factors (TRAFs), and that inhibits nuclear factor-kappa B activation.

TRAF3 TRAF5

1.31e-04876210764746
Pubmed

SHH-N upregulates Sfrp2 to mediate its competitive interaction with WNT1 and WNT4 in the somitic mesoderm.

SFRP4 FRZB

1.31e-04876210654605
Pubmed

The Fn14 cytoplasmic tail binds tumour-necrosis-factor-receptor-associated factors 1, 2, 3 and 5 and mediates nuclear factor-kappaB activation.

TRAF3 TRAF5

1.31e-04876212529173
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

RLF MKRN1 ZNF521 ZNF226 FHL2 ZNF426 CRIP2 ZFY

1.60e-0470976822988430
Pubmed

ARRB1 ameliorates liver ischaemia/reperfusion injury via antagonizing TRAF6-mediated Lysine 6-linked polyubiquitination of ASK1 in hepatocytes.

TRAF3 TRAF5

1.68e-04976232445435
Pubmed

An Internally Translated MAVS Variant Exposes Its Amino-terminal TRAF-Binding Motifs to Deregulate Interferon Induction.

TRAF3 TRAF5

1.68e-04976226221961
Pubmed

TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin ligase.

TRAF3 TRAF5

1.68e-04976217544371
Pubmed

MAVS activates TBK1 and IKKε through TRAFs in NEMO dependent and independent manner.

TRAF3 TRAF5

1.68e-04976229125880
Pubmed

Toll-like receptor 3-mediated activation of NF-kappaB and IRF3 diverges at Toll-IL-1 receptor domain-containing adapter inducing IFN-beta.

TRAF3 TRAF5

1.68e-04976214982987
Pubmed

Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.

ZNF729 ZNF43 ZNF681

1.72e-04497639630514
Pubmed

Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development.

SFRP4 FRZB

2.10e-041076223087175
Pubmed

UBE2O negatively regulates TRAF6-mediated NF-κB activation by inhibiting TRAF6 polyubiquitination.

TRAF3 TRAF5

2.10e-041076223381138
Pubmed

Functional analysis of the SRY-KRAB interaction in mouse sex determination.

ZNF729 ZNF43

2.10e-041076218588511
Pubmed

TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction.

TRAF3 TRAF5

2.10e-041076210514511
Pubmed

Sry associates with the heterochromatin protein 1 complex by interacting with a KRAB domain protein.

ZNF729 ZNF43

2.56e-041176215469996
Pubmed

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung.

SFRP4 FRZB

2.56e-041176211731265
Pubmed

MAVS recruits multiple ubiquitin E3 ligases to activate antiviral signaling cascades.

TRAF3 TRAF5

2.56e-041176223951545
Pubmed

TRAF3IP3 mediates the recruitment of TRAF3 to MAVS for antiviral innate immunity.

TRAF3 TRAF5

3.07e-041276231390091
Pubmed

Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.

ANXA1 MATN2 MKRN1 FHL2

3.18e-0414876422898364
Pubmed

A phospho/methyl switch at histone H3 regulates TFIID association with mitotic chromosomes.

PHF2 BPTF

3.62e-041376220953165
Pubmed

Epigenetic gene silencing by the SRY protein is mediated by a KRAB-O protein that recruits the KAP1 co-repressor machinery.

ZNF729 ZNF43

3.62e-041376219850934
Pubmed

HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating component of the CD40 signaling complex.

TRAF3 TRAF5

3.62e-041376220614026
Pubmed

A genome-wide association study on common SNPs and rare CNVs in anorexia nervosa.

NALF1 ZNF804B

3.62e-041376221079607
Pubmed

The ectodermal dysplasia receptor activates the nuclear factor-kappaB, JNK, and cell death pathways and binds to ectodysplasin A.

TRAF3 TRAF5

3.62e-041376211035039
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

RLF PHF2 BPTF ZNF813 ZNF226 SPEN ZMYM4

3.72e-0460876736089195
Pubmed

Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis.

TP63 FRZB

4.86e-041576224590292
Pubmed

Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.

ZDHHC20 ZDHHC16

5.54e-041676223034182
Pubmed

Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland.

ANXA1 TP63

5.54e-041676238760574
Pubmed

A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains.

TRAF3 TRAF5

5.54e-041676211279055
Pubmed

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes.

BPTF SETD1A

6.27e-041776221653943
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

PHF2 ZNF556 TP63 ZDHHC16 ZNF226 FHL2 SPEN ZFY

6.58e-0487776820211142
Pubmed

USF1 recruits histone modification complexes and is critical for maintenance of a chromatin barrier.

BPTF SETD1A

7.05e-041876217846119
Pubmed

The contribution of de novo coding mutations to autism spectrum disorder.

PHF2 SPEN

7.05e-041876225363768
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

BPTF TP63 SPEN

8.13e-048376328794006
Pubmed

Tagging genes with cassette-exchange sites.

BPTF OXSR1 ZMYM4 ZNF681 JAM2

8.50e-0433576515741177
Pubmed

Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.

ZNF426 ZNF681

8.73e-04207627479878
Pubmed

Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.

ZNF426 ZNF681

8.73e-04207622542606
CytobandEnsembl 112 genes in cytogenetic band chr19p12

ZNF729 ZNF43 ZNF90 ZNF626 ZNF681

1.94e-06122765chr19p12
Cytoband19p12

ZNF729 ZNF90 ZNF626 ZNF681

1.59e-059076419p12
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF729 RLF ZNF717 ZNF556 ZNF341 ZNF43 ZNF813 ZNF521 ZNF571 ZNF226 ZNF90 ZNF319 ZNF626 ZNF791 ZNF583 ZNF426 ZNF681 ZFY ZIC3 ZNF114 PRDM1

5.26e-15718602128
GeneFamilySecreted frizzled-related proteins

SFRP4 FRZB

1.08e-045602733
GeneFamilyTNF receptor associated factors

TRAF3 TRAF5

2.25e-0476021056
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC20 ZDHHC16

2.85e-032460276
ToppCell5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HIPK3 NALF1 ZNF521 OSMR CRIP2 JAM2

1.17e-0619976607bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF556 FGD4 ZNF804B CNPY3 ZNF90

5.88e-061507656c39e73a0b05d4b26589f333ce13924e3d373b8d
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NALF1 ADAMTS6 ZNF521 CRIP2 JAM2

1.18e-05173765b7d8702409b86fbc8741a472b84d509ba261a852
ToppCell3'-Airway_Nasal-Endothelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NALF1 ADAMTS6 ZNF521 CRIP2 JAM2

1.18e-05173765383edcd3bb14d3934506260dbbac7167282546af
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NALF1 ADAMTS6 ZNF521 CRIP2 JAM2

1.18e-05173765b83c9e274999c9325908616cee4a89d425c8c4ed
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NALF1 ADAMTS6 ZNF521 CRIP2 JAM2

1.18e-051737650068c059ef118b5ef85c5b01ad8680ce11493aa5
ToppCell3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NALF1 ADAMTS6 ZNF521 CRIP2 JAM2

1.18e-051737653c96e269ca7b7029f533268f68ca4466edd20edd
ToppCell3'-Child09-12-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ZNF521 UNC13A CRIP2 JAM2

1.50e-051827653cbeaf7904a76c32137a00abb20e302d3d3c8bb8
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B PDGFC CHN2 CRIP2

1.58e-05184765ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B PDGFC CHN2 CRIP2

1.58e-05184765219bd3b8daa0a713fb6a8a5e1bb35cdb85bb7727
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B PDGFC CHN2 CRIP2

1.67e-0518676577b09af860183606a1775eba921e2071e4a7dd4e
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein|Children_(3_yrs) / Lineage, Cell type, age group and donor

NALF1 ZNF521 OSMR CRIP2 JAM2

1.71e-05187765e35716f8b482be3bf5ab79f087a9caf67a9d197a
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC CRIP2

1.75e-05188765f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 MATN2 FHL2 PDGFC

1.75e-051887653004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 MATN2 FHL2 PDGFC

1.80e-05189765b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 MATN2 FHL2 PDGFC

1.80e-05189765f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC CRIP2

1.85e-05190765938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellNS-moderate-d_16-33-Epithelial-Squamous|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DUSP5 OSMR FHL2 ZNF114 PRDM1

1.94e-05192765103496f428f59683ac3ae6147682c07c30663724
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRAF5 ADAMTS6 DUSP5 FHL2 PDGFC

1.99e-051937654aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CFAP47 ANXA1 DUSP5 OSMR FHL2

1.99e-05193765ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP4 MATN2 FRZB CCL21 FHL2

1.99e-05193765dc8e62df6121ee99b156aca6b1b3ae555739b6f2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRAF5 ADAMTS6 DUSP5 FHL2 PDGFC

1.99e-051937655578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HIPK3 NALF1 OSMR CRIP2 JAM2

1.99e-05193765c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP4 MATN2 FRZB CCL21 FHL2

1.99e-05193765e2ee077fd381bd906e6b4329f22e7d106e422a7f
ToppCellIPF-Endothelial|IPF / Disease state, Lineage and Cell class

NALF1 ZNF521 CCL21 CRIP2 JAM2

2.04e-051947659591993aa2dcba3d09a0f1ea8b8f2439c26482d6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC CRIP2

2.04e-0519476567f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellIPF-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

NALF1 ZNF521 OSMR CRIP2 JAM2

2.09e-05195765120296531bbc8080dcabacbd64733cc1dc34603a
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-MYL4+_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 MATN2 FHL2 PDGFC

2.09e-05195765dba2a87efd7e067c094c4b367feb4138cab62735
ToppCellIPF-Endothelial-VE_Peribronchial|IPF / Disease state, Lineage and Cell class

NALF1 ZNF521 OSMR CRIP2 JAM2

2.09e-051957652c3ad3cb79f11119ac69c413a938d21199145040
ToppCell11.5-Distal-Mesenchymal-Airway_Smooth_Muscle|Distal / Age, Tissue, Lineage and Cell class

TRAF5 ADAMTS6 MATN2 FHL2 PDGFC

2.14e-0519676505530fe7a5681c2f39b95016cd22ef99d6ac0430
ToppCell5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ZNF521 OSMR CRIP2 JAM2

2.20e-0519776587eda06344498dc66cac292cf89746dc90b5cf67
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SFRP4 MATN2 FRZB UNC13A JAM2

2.20e-051977652cb1f557ce1400398975de94638126b4522567f3
ToppCell3'-Child09-12-SmallIntestine-Endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ZNF521 CCL21 CRIP2 JAM2

2.20e-0519776586a02fd7b4762b3278e5e60b5483b5fc1206e597
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SFRP4 MATN2 FRZB CCL21 FHL2

2.20e-051977654cf4e9553397cd8dee883dbec24f41bec41aff99
ToppCell3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 MATN2 ZNF521 CRIP2 JAM2

2.20e-051977657a1a3839b2c965136663241b0d4e96c64cfb656a
ToppCelldistal-Endothelial-Vein-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NALF1 MATN2 ZNF521 CRIP2 JAM2

2.30e-05199765f9fc0482d7ab11f2165b30cce3564b4ff87d61a6
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

NALF1 MATN2 OSMR CRIP2 JAM2

2.36e-0520076584e145619a500530f42ed0fe72468ae95f4cbf1e
ToppCell3'-Adult-LargeIntestine-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF521 OSMR CCL21 CRIP2 JAM2

2.36e-0520076574a3b9ec8faa1d187ad8b0d12f5c89bde2d7248e
ToppCellTransverse|World / shred on region, Cell_type, and subtype

ZFAND2A ANXA1 DUSP5 DNAJC1 PRDM1

2.36e-052007651b4925a17be02f99b69c45f66577986a2dc107fd
ToppCellTransverse|World / Region, Cell class and subclass

ZFAND2A ANXA1 DUSP5 DNAJC1 PRDM1

2.36e-052007659dee983d7e43af8b3fbed795d8432af67b33c3b3
ToppCelldistal-Endothelial-Vein-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NALF1 MATN2 OSMR CRIP2 JAM2

2.36e-05200765ff88d28162e0231d5dac0e0c6bec98fa8da58a23
ToppCell3'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ZNF521 OSMR CRIP2 JAM2

2.36e-05200765cee07d9370656e1c428a7a9e9fbd175129901374
ToppCelldistal-2-Endothelial-Vein|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NALF1 MATN2 OSMR CRIP2 JAM2

2.36e-052007652785225956d2422acab90e99b7debe3709cf3308
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

BPTF FGD4 MATN2 ZNF90 SPEN

2.36e-052007657c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCelldistal-Endothelial-Vein|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

NALF1 MATN2 OSMR CRIP2 JAM2

2.36e-052007656acf7afe122f81a95c4c66f4d0878d997b57127a
ToppCellLA-10._Endothelium_II|World / Chamber and Cluster_Paper

NALF1 ZDHHC16 CCL21 LRIT3

6.84e-05128764071becbe97598c2b65580b0989eb664d6fd6c85a
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKD3 ARV1 FGD4 MATN2

1.20e-04148764b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRKD3 ARV1 FGD4 MATN2

1.20e-04148764ba277c898678dd36f8dc1d681301c71901b89055
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D175|Adult / Lineage, Cell type, age group and donor

NALF1 ZNF521 UNC13A JAM2

2.00e-04169764e1f0298236e4a1c59077c14f0dd29a78fac12648
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF521 CAPS2 ZMYM4 JAM2

2.00e-04169764f086b50791e1c93e253eb5e8d6c4bf617b1416c3
ToppCellEndothelial-B-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

NALF1 ZNF521 CCL21 CRIP2

2.14e-04172764d4e98ff9c7cbc95457e1d71fa60f151a2f178dae
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MATN2 ZNF521 CRIP2 JAM2

2.14e-04172764a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B CHN2 CRIP2

2.23e-04174764bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCellBasal_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

ZNF556 TP63 ZNF426 CRIP2

2.23e-04174764a0060be3940043015dcc49a5157de5541aed24a1
ToppCellAdult-Endothelial-endothelial_cell_of_vein-D231|Adult / Lineage, Cell type, age group and donor

NALF1 ADAMTS6 ZNF521 JAM2

2.23e-041747642dd647c4fdf99fd1f7b838efef01baf2cbc3446d
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRKD3 SETD1A TP63 CCL21

2.28e-0417576443be63976da5ad0764d24d90919a77ce46068f52
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB|TCGA-Thymus / Sample_Type by Project: Shred V9

SFRP4 FRZB ZNF114 JAM2

2.28e-0417576450f9b994bdd389158f92f891944ea81b2fb15eef
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_NK-T_mait-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

FRZB DUSP5 ZFY PRDM1

2.38e-04177764605f71515c877bb4de4121675ec8c1318a2500a7
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B CHN2 CRIP2

2.43e-04178764b169aa5eaa51730daaec69c6bc58126be1592a50
ToppCell3'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS6 ZNF521 CRIP2 JAM2

2.43e-04178764e2363810d77b6b245394a666eb51bacd345c43f7
ToppCelldroplet-Spleen-nan-3m-Hematologic-erythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAF5 MKRN1 LMBRD2

2.44e-0471763aa4bad3a59780281a900d3bb7f7b02010cf6a17f
ToppCellCOPD-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

NALF1 OSMR CRIP2 JAM2

2.49e-041797649968da1adcb561d9bf167a42ab5d9de85c071c4a
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|343B / Donor, Lineage, Cell class and subclass (all cells)

DCP1B ZDHHC16 IPP PRDM1

2.49e-04179764c09c3eed43d1aa3b7aa8f3021e6f2737840cde16
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZNF804B PDGFC CHN2 CRIP2

2.49e-04179764445eeb0356d9fd894aa33dd9f45d893b21424149
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

NALF1 ADAMTS6 CRIP2 JAM2

2.49e-041797641ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_vein-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NALF1 ZNF521 CRIP2 JAM2

2.54e-0418076427e8bbee388e64dd79d70b160b76d45b1f398006
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZFAND2A DUSP5 FHL2 PDGFC

2.65e-0418276437547b36264090b49a193a8ef3a8d88e647f0b79
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ZNF521 CRIP2 JAM2

2.65e-04182764d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B CHN2 CRIP2

2.65e-04182764205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCelltumor_Lymph_Node_/_Brain-Endothelial_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MATN2 ZNF521 CCL21 JAM2

2.65e-04182764d7cce5dd7046f06bf40f00c9dbfa610722b03333
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANXA1 ZNF804B CHN2 CRIP2

2.70e-0418376401ad18f198195ce341bae01a1c8c253cc4607766
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ADAMTS6 MATN2 FHL2 PDGFC

2.70e-04183764e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TP63 CD151 FHL2 CRIP2

2.70e-04183764ec2af3402b51f11466d2a5783a6b33746b6a7fc9
ToppCellCOVID-19-Heart-EC_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

NALF1 ZNF521 OSMR JAM2

2.70e-04183764ff95382cfed592190d0636d2b750328471f82e0d
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NALF1 ADAMTS6 ZNF521 JAM2

2.70e-04183764c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellCOPD-Endothelial-VE_Venous|COPD / Disease state, Lineage and Cell class

NALF1 OSMR CRIP2 JAM2

2.76e-0418476444d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

SFRP4 FRZB ZNF521 JAM2

2.82e-04185764e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SFRP4 MATN2 FRZB ZNF521

2.82e-04185764ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellEndothelial-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

NALF1 ZNF521 CRIP2 JAM2

2.82e-04185764ae49c61f6ecf128fe2a958b8c75c83688da75f59
ToppCellControl-Endothelial-Endothelial-Vein|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NALF1 ADAMTS6 ZNF521 JAM2

2.88e-0418676492092f11ecce22c14f244e42c499af0822977e6f
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF521 CCL21 FHL2 CRIP2

2.88e-041867647a8da2ad140bea3207bd868212cc5e201d586772
ToppCell343B-Endothelial_cells-Endothelial-F_(Lymphatics)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ZNF521 CCL21 FHL2 CRIP2

2.88e-04186764dc394034929c6b10ae0e1c1a028cc3d4ce873298
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC

2.94e-04187764387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRZB OSMR CRIP2 JAM2

2.94e-0418776412129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

NALF1 ADAMTS6 ZNF521 JAM2

2.94e-041877642d20193a6cacdfa4877457c97b0077408942186c
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FRZB OSMR CRIP2 JAM2

2.94e-0418776483930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ZNF521 CRIP2 JAM2

2.94e-04187764d6765854154557794815514c0aa355bc74b8523e
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC

3.00e-0418876474f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellCOVID-19-lung-Vein_EC|lung / Disease (COVID-19 only), tissue and cell type

NALF1 ADAMTS6 ZNF521 JAM2

3.00e-04188764d582b76fc2faac526c9bf97503041129e1a6a211
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TRAF5 ANXA1 CD151 CRIP2

3.00e-0418876494774652fd42bad5012356672ffac8b6d2c22d37
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

NALF1 PRR9 OSMR FHL2

3.06e-0418976479bb2593ad5d17f94b17972884241f03a0f43770
ToppCellControl-Endothelial-VE_Peribronchial|World / Disease state, Lineage and Cell class

ZNF521 OSMR CRIP2 JAM2

3.06e-04189764c76d8af2e0aa4a83ee0c3439c894566fbf117dd3
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

NALF1 OSMR CRIP2 JAM2

3.06e-04189764f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCellEndothelial-endothelial_cell_of_artery|World / Lineage, Cell type, age group and donor

ADAMTS6 DUSP5 CRIP2 JAM2

3.06e-04189764fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC

3.06e-04189764da9ecc0d7b81c1901f30f97bb44112dc85444a66
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NALF1 ANXA1 ZNF521 CRIP2

3.06e-04189764fccadf8efbef17b7f12291b069c71060a71b04e2
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like|bone_marrow / Manually curated celltypes from each tissue

ANXA1 MATN2 DUSP5 PRDM1

3.06e-04189764ac2995e599f3d1813218479dc515b1d612c0ef8b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TRAF5 ADAMTS6 FHL2 PDGFC

3.06e-041897640abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-MAIT|lymph-node_spleen / Manually curated celltypes from each tissue

ANXA1 MATN2 DUSP5 PRDM1

3.06e-04189764afe3a4fe7c10eeeb7064129778d940269c9acbef
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZNF521 CD151 CCL21 CRIP2

3.12e-0419076432400c62cb9de4c2b24af4206c21a0215ab12212
DiseaseDiffuse Large B-Cell Lymphoma

TRAF5 SPEN PRDM1

2.82e-0455683C0079744
Diseasewellbeing measurement, alcohol consumption measurement

ACTR3C USH2A UNC13A

6.75e-0474683EFO_0007869, EFO_0007878
Diseaseserum IgG measurement

TRAF3 UNC13A

7.82e-0418682EFO_0004565
Diseaseage at first sexual intercourse measurement

PHF2 BPTF NALF1 MKRN1 ZNF521

1.91e-03383685EFO_0009749

Protein segments in the cluster

PeptideGeneStartEntry
ASYCSKEKEKVPCIL

UNC13A

1241

Q9UPW8
CCLKYSQRKIPAKVV

CCL21

31

O00585
CIKEVECYVSRPTEK

GJD2

236

Q9UKL4
SVPIINIRKCYCAKK

CAPS2

536

Q9BXY5
AIKEKYCYICPDIVK

ACTR3B

226

Q9P1U1
ETKKDTKLYCICKTP

BPTF

2861

Q12830
CVPSKSKEDCIARYK

DNAJC1

526

Q96KC8
EECKDVNKVAYCPLV

ADAMTS6

1081

Q9UKP5
CCKYKIDNPEEKALI

OSMR

686

Q99650
LKEYCEVCKSPKENK

IPP

256

Q9Y573
VQAAYCAPKKEKVAI

OXSR1

31

O95747
CNECQCVPSKVTKKY

PDGFC

291

Q9NRA1
EKCLTAIVKCATSKP

ANXA1

261

P04083
ALNPDKKTCTKIDYC

MATN2

351

O00339
PQCEKTVDVKKSKFC

nan

16

A8MVJ9
KAIKEKYCYICPDIV

ACTR3C

96

Q9C0K3
KLSKVCKDCYQIISG

FGD4

606

Q96M96
KDLVCSIVYQKFPEC

PRKD3

86

O94806
FLLYKVCKLQCKSEP

LRIT3

601

Q3SXY7
VEYQEAILACKTPKK

JAM2

41

P57087
CSVKKLKVEPSSCVF

HIPK3

21

Q9H422
TELKKLYCQIAKTCP

TP63

196

Q9H3D4
IKKVYCCDLTTLVKA

CHN2

271

P52757
EYTKCKTCSEPKKIT

DCP1B

171

Q8IZD4
TICKSCQKPVDKYIE

ARV1

56

Q9H2C2
PSKCEVCKYVAVELK

CNPY3

46

Q9BT09
EYSSKCQECKKTIMP

FHL2

96

Q14192
KKLNCYKITLECLPQ

GNPNAT1

146

Q96EK6
CPRCSKKVYFAEKVT

CRIP2

126

P52943
EKKTTCGTVCLKYLL

CD151

6

P48509
YILCKTEAKCCVDPK

DEFB121

41

Q5J5C9
TEAKCCVDPKYVPVK

DEFB121

46

Q5J5C9
FKAIDIIKCESPCYQ

CFAP47

1976

Q6ZTR5
YPECCVDVKPISQEK

DUSP5

136

Q16690
KQFESKIIKSCPECR

MKRN1

321

Q9UHC7
VKCCETELIPKSQKC

USH2A

3356

O75445
PKVTKYCLICVKDSY

PHF2

231

O75151
KCVDTILKKCPTEYQ

LMBRD2

266

Q68DH5
EKPYQCKVCPAKFTQ

PRDM1

656

O75626
PNCYAKVITIESQKK

SETD1A

1651

O15047
EKCLYCKKDVVVINL

TRAF5

166

O00463
SEKTCKQLDFLPVKC

ZFAND2A

11

Q8N6M9
VHTSDKPYICKVCDK

ZIC3

381

O60481
PKCTACQESIVKDKV

TRAF3

86

Q13114
KCVKCVNKYSTPEAL

ZNF341

541

Q9BYN7
ASKTIRYCEKCQLIK

ZDHHC20

121

Q5W0Z9
SPIYKTKQTADKCKC

ZNF804B

251

A4D1E1
TKKTAGVKPYECTIC

ZNF791

91

Q3KP31
LQYCDIASVCKAIKK

SPEN

481

Q96T58
IYTCPVCIKKFKRKE

RLF

581

Q13129
ERCKCKPIRATQKTY

FRZB

176

Q92765
IVGKKQTCPYCKEKV

RNF175

266

Q8N4F7
DRCKCKKVKPTLATY

SFRP4

176

Q6FHJ7
PSQSDEKKTYQCIKC

ZNF521

1186

Q96K83
VKSQTREKVYKCETC

ZNF556

361

Q9HAH1
KCVEVCPQKVQEKCS

PRR9

96

Q5T870
VGKKQTCPYCKEKVD

RNF121

266

Q9H920
EKPYKCTECVKTFSR

ZNF813

436

Q6ZN06
IATVSICKKCIYPKP

ZDHHC16

151

Q969W1
KIIHTEEKPYKCEEC

ZNF43

641

P17038
EIIHTEKKPYKCEEC

ZNF626

276

Q68DY1
QKVHVIEKPYKCKQC

ZNF226

326

Q9NYT6
KPYECVECEKPSISK

ZNF717

281

Q9BY31
GLVKCSICEKTYKPA

ZNF319

156

Q9P2F9
KISHTEEKPYKCQEC

ZNF90

416

Q03938
KFEVYCKKIPSECSI

VPS13B

3276

Q7Z7G8
KNIHTEEKPYKCEEC

ZNF681

441

Q96N22
ITVYAALCCEIKKLK

WASHC4

91

Q2M389
IIPTKEKLYKCKECR

ZNF571

131

Q7Z3V5
IETLNAKKPYKCKEC

ZNF426

271

Q9BUY5
KCPDQKCLYTCQIKD

TBRG1

226

Q3YBR2
KPYECKVCRKAFSQI

ZNF583

406

Q96ND8
YKQKSAKITPCALCK

ZMYM4

521

Q5VZL5
PCKVDSTCPEVIKVY

ZFY

236

P08048
KVIHTAEKPYKCEDC

ZNF729

311

A6NN14
KIIHSVEKPYKCEEC

ZNF729

1151

A6NN14
VQKKPYECEECGKVI

ZNF114

356

Q8NC26
SVKSCPEDCKIVYKA

NALF1

296

B1AL88
CLKTTAKCSKKYDPE

MYO9A

2041

B2RTY4