Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	delta14-sterol reductase activity	LBR TM7SF2	3.35e-05	2	116	2	GO:0050613
GeneOntologyMolecularFunction	vinculin binding	DAG1 DMD UTRN	5.24e-05	13	116	3	GO:0017166
GeneOntologyMolecularFunction	anandamide 8,9 epoxidase activity	CYP2D7 CYP2D6	1.99e-04	4	116	2	GO:0062187
GeneOntologyMolecularFunction	anandamide 11,12 epoxidase activity	CYP2D7 CYP2D6	1.99e-04	4	116	2	GO:0062188
GeneOntologyMolecularFunction	steroid 21-monooxygenase activity	CYP2D7 CYP2D6	1.99e-04	4	116	2	GO:0004509
GeneOntologyMolecularFunction	progesterone 21-hydroxylase activity	CYP2D7 CYP2D6	1.99e-04	4	116	2	GO:0106309
GeneOntologyMolecularFunction	cytoskeletal protein binding	EML4 SPTA1 SPTB OBSCN DAG1 EML3 CYFIP1 CCDC88A DST NF1 NISCH MACF1 DMD UTRN UNC13A MYO16 TBCEL	2.03e-04	1099	116	17	GO:0008092
GeneOntologyMolecularFunction	H3K27me3 modified histone binding	TAF1 TAF1L	3.31e-04	5	116	2	GO:0061628
GeneOntologyMolecularFunction	actin binding	SPTA1 SPTB DAG1 CYFIP1 CCDC88A DST MACF1 DMD UTRN MYO16	4.85e-04	479	116	10	GO:0003779
GeneOntologyMolecularFunction	anandamide 14,15 epoxidase activity	CYP2D7 CYP2D6	4.94e-04	6	116	2	GO:0062189
GeneOntologyMolecularFunction	anandamide epoxidase activity	CYP2D7 CYP2D6	4.94e-04	6	116	2	GO:0062186
GeneOntologyMolecularFunction	tubulin binding	EML4 DAG1 EML3 CCDC88A DST NF1 NISCH MACF1 TBCEL	8.87e-04	428	116	9	GO:0015631
GeneOntologyMolecularFunction	TBP-class protein binding	BTAF1 TAF1 TAF1L	9.18e-04	33	116	3	GO:0017025
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	LBR TM7SF2 AKR1B1	1.00e-03	34	116	3	GO:0016628
GeneOntologyMolecularFunction	RNA polymerase I general transcription initiation factor activity	TAF1 TAF1L	1.17e-03	9	116	2	GO:0001181
GeneOntologyCellularComponent	dystrophin-associated glycoprotein complex	DAG1 DMD UTRN	1.82e-04	20	117	3	GO:0016010
GeneOntologyCellularComponent	zeta DNA polymerase complex	POLD2 REV3L	1.85e-04	4	117	2	GO:0016035
GeneOntologyCellularComponent	excitatory synapse	PPFIA4 CHD4 CYFIP1 PLCB4 UNC13A	3.40e-04	107	117	5	GO:0060076
GeneOntologyCellularComponent	glycoprotein complex	DAG1 DMD UTRN	3.59e-04	25	117	3	GO:0090665
MousePheno	hepatic necrosis	SPTA1 SPTB NF1 IGFBP1 MME PROS1	1.30e-05	79	92	6	MP:0001654
MousePheno	cerebral infarct	SPTA1 SPTB	4.28e-05	2	92	2	MP:0021003
Domain	Spectrin	SPTA1 SPTB DST MACF1 DMD UTRN	3.77e-09	23	112	6	PF00435
Domain	Spectrin_repeat	SPTA1 SPTB DST MACF1 DMD UTRN	1.72e-08	29	112	6	IPR002017
Domain	SPEC	SPTA1 SPTB DST MACF1 DMD UTRN	3.24e-08	32	112	6	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTB DST MACF1 DMD UTRN	3.24e-08	32	112	6	IPR018159
Domain	ACTININ_2	SPTB DST MACF1 DMD UTRN	2.19e-07	23	112	5	PS00020
Domain	ACTININ_1	SPTB DST MACF1 DMD UTRN	2.19e-07	23	112	5	PS00019
Domain	Actinin_actin-bd_CS	SPTB DST MACF1 DMD UTRN	2.19e-07	23	112	5	IPR001589
Domain	ARM-like	DOCK10 XPO4 ZYG11B BTAF1 HEATR1 RSPRY1 NF1 MROH7 GCN1 MED12	5.23e-06	270	112	10	IPR011989
Domain	TFIID_sub1_DUF3591	TAF1 TAF1L	3.56e-05	2	112	2	IPR022591
Domain	TBP-binding	TAF1 TAF1L	3.56e-05	2	112	2	PF09247
Domain	DUF3591	TAF1 TAF1L	3.56e-05	2	112	2	PF12157
Domain	Dystrophin	DMD UTRN	3.56e-05	2	112	2	IPR016344
Domain	TAF_II_230-bd	TAF1 TAF1L	3.56e-05	2	112	2	IPR009067
Domain	-	TAF1 TAF1L	3.56e-05	2	112	2	1.10.1100.10
Domain	TAF1_animal	TAF1 TAF1L	3.56e-05	2	112	2	IPR011177
Domain	CH	SPTB DST MACF1 DMD UTRN	4.40e-05	65	112	5	SM00033
Domain	-	XPO4 ZYG11B BTAF1 HEATR1 NF1 MROH7 GCN1 MED12	5.79e-05	222	112	8	1.25.10.10
Domain	CH	SPTB DST MACF1 DMD UTRN	6.29e-05	70	112	5	PF00307
Domain	-	SPTB DST MACF1 DMD UTRN	6.73e-05	71	112	5	1.10.418.10
Domain	CH	SPTB DST MACF1 DMD UTRN	7.70e-05	73	112	5	PS50021
Domain	CH-domain	SPTB DST MACF1 DMD UTRN	8.76e-05	75	112	5	IPR001715
Domain	Sterol_reductase_CS	LBR TM7SF2	1.07e-04	3	112	2	IPR018083
Domain	ERG4_ERG24	LBR TM7SF2	1.07e-04	3	112	2	PF01222
Domain	Ergosterol_biosynth_ERG4_ERG24	LBR TM7SF2	1.07e-04	3	112	2	IPR001171
Domain	STEROL_REDUCT_2	LBR TM7SF2	1.07e-04	3	112	2	PS01018
Domain	STEROL_REDUCT_1	LBR TM7SF2	1.07e-04	3	112	2	PS01017
Domain	C2	UNC13D PLCD4 HECW2 PLCB4 SMURF2 UNC13A	1.38e-04	131	112	6	PF00168
Domain	C2	UNC13D PLCD4 HECW2 PLCB4 SMURF2 UNC13A	1.77e-04	137	112	6	SM00239
Domain	-	SPTA1 FKBP9 PLCD4 DST MACF1 PLCB4 DMD UTRN	1.78e-04	261	112	8	1.10.238.10
Domain	WW	HECW2 DMD UTRN SMURF2	1.79e-04	47	112	4	PF00397
Domain	WW	HECW2 DMD UTRN SMURF2	1.95e-04	48	112	4	SM00456
Domain	ARM-type_fold	XPO4 ZYG11B BTAF1 HEATR1 RSPRY1 URB1 NF1 MROH7 GCN1	2.05e-04	339	112	9	IPR016024
Domain	IZUMO	IZUMO4 IZUMO1	2.12e-04	4	112	2	IPR029389
Domain	IZUMO	IZUMO4 IZUMO1	2.12e-04	4	112	2	PF15005
Domain	C2	UNC13D PLCD4 HECW2 PLCB4 SMURF2 UNC13A	2.15e-04	142	112	6	PS50004
Domain	WW_DOMAIN_1	HECW2 DMD UTRN SMURF2	2.46e-04	51	112	4	PS01159
Domain	WW_DOMAIN_2	HECW2 DMD UTRN SMURF2	2.46e-04	51	112	4	PS50020
Domain	WW_dom	HECW2 DMD UTRN SMURF2	2.66e-04	52	112	4	IPR001202
Domain	-	UNC13D PLCD4 HECW2 PLCB4 SMURF2 UNC13A	2.68e-04	148	112	6	2.60.40.150
Domain	EF-hand-dom_pair	SPTA1 FKBP9 PLCD4 DST MACF1 PLCB4 DMD UTRN	3.37e-04	287	112	8	IPR011992
Domain	Munc13_dom-2	UNC13D UNC13A	3.52e-04	5	112	2	IPR014772
Domain	MHD2	UNC13D UNC13A	3.52e-04	5	112	2	PS51259
Domain	Munc13_subgr_dom-2	UNC13D UNC13A	3.52e-04	5	112	2	IPR019558
Domain	Membr_traf_MHD	UNC13D UNC13A	3.52e-04	5	112	2	PF10540
Domain	C2_dom	UNC13D PLCD4 HECW2 PLCB4 SMURF2 UNC13A	4.65e-04	164	112	6	IPR000008
Domain	-	DST MACF1	5.26e-04	6	112	2	3.90.1290.10
Domain	GAR	DST MACF1	5.26e-04	6	112	2	PS51460
Domain	HELP	EML4 EML3	5.26e-04	6	112	2	PF03451
Domain	GAS2	DST MACF1	5.26e-04	6	112	2	PF02187
Domain	EF-hand_dom_typ1	DMD UTRN	5.26e-04	6	112	2	IPR015153
Domain	EF-hand_dom_typ2	DMD UTRN	5.26e-04	6	112	2	IPR015154
Domain	-	DST MACF1	5.26e-04	6	112	2	3.30.920.20
Domain	HELP	EML4 EML3	5.26e-04	6	112	2	IPR005108
Domain	EF-hand_2	DMD UTRN	5.26e-04	6	112	2	PF09068
Domain	EF-hand_3	DMD UTRN	5.26e-04	6	112	2	PF09069
Domain	GAS_dom	DST MACF1	5.26e-04	6	112	2	IPR003108
Domain	GAS2	DST MACF1	5.26e-04	6	112	2	SM00243
Domain	Munc13_1	UNC13D UNC13A	7.34e-04	7	112	2	IPR014770
Domain	MHD1	UNC13D UNC13A	7.34e-04	7	112	2	PS51258
Domain	Plectin	DST MACF1	7.34e-04	7	112	2	PF00681
Domain	DUF1041	UNC13D UNC13A	7.34e-04	7	112	2	PF06292
Domain	Plectin_repeat	DST MACF1	7.34e-04	7	112	2	IPR001101
Domain	CAPS_dom	UNC13D UNC13A	7.34e-04	7	112	2	IPR010439
Domain	PLEC	DST MACF1	7.34e-04	7	112	2	SM00250
Domain	HEAT_REPEAT	BTAF1 HEATR1 MROH7 GCN1	8.29e-04	70	112	4	PS50077
Domain	CRAL_TRIO_2	PRUNE2 NF1	2.26e-03	12	112	2	PF13716
Domain	EFh	SPTA1 FKBP9 PLCD4 DST MACF1	2.64e-03	158	112	5	SM00054
Domain	ER_TARGET	FKBP9 COLGALT1 UGGT2	2.81e-03	47	112	3	PS00014
Domain	HEAT	BTAF1 HEATR1 GCN1	2.98e-03	48	112	3	PF02985
Domain	EF-hand_like	PLCD4 PLCB4	3.56e-03	15	112	2	PF09279
Domain	PI-PLC-Y	PLCD4 PLCB4	3.56e-03	15	112	2	PF00387
Domain	PLCYc	PLCD4 PLCB4	3.56e-03	15	112	2	SM00149
Domain	PLipase_C_Pinositol-sp_Y	PLCD4 PLCB4	3.56e-03	15	112	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCD4 PLCB4	3.56e-03	15	112	2	PS50008
Domain	PI-PLC_fam	PLCD4 PLCB4	3.56e-03	15	112	2	IPR001192
Domain	PLC_EF-hand-like	PLCD4 PLCB4	3.56e-03	15	112	2	IPR015359
Domain	UBIQUITIN_2	RBCK1 SACS TBCEL	4.17e-03	54	112	3	PS50053
Domain	HEAT	BTAF1 HEATR1 GCN1	5.10e-03	58	112	3	IPR000357
Domain	Ubiquitin_dom	RBCK1 SACS TBCEL	5.10e-03	58	112	3	IPR000626
Domain	ZF_ZZ_2	DMD UTRN	5.12e-03	18	112	2	PS50135
Domain	PI-PLC-X	PLCD4 PLCB4	5.12e-03	18	112	2	PF00388
Domain	ZF_ZZ_1	DMD UTRN	5.12e-03	18	112	2	PS01357
Domain	PLCXc	PLCD4 PLCB4	5.12e-03	18	112	2	SM00148
Domain	ZZ	DMD UTRN	5.12e-03	18	112	2	PF00569
Domain	Znf_ZZ	DMD UTRN	5.70e-03	19	112	2	IPR000433
Domain	PIPLC_X_DOMAIN	PLCD4 PLCB4	5.70e-03	19	112	2	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	PLCD4 PLCB4	5.70e-03	19	112	2	IPR000909
Domain	ZnF_ZZ	DMD UTRN	5.70e-03	19	112	2	SM00291
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SART3 ARHGEF28 EML4 DOCK10 BTAF1 COLGALT1 RSPRY1 CUL5 PARP4 CCDC88A DST RPAP1 SUPV3L1 WDCP NISCH TCF25 UGGT2 TIMELESS ZBED1	7.03e-13	650	117	19	38777146
Pubmed	N-terminal α Dystroglycan (αDG-N): A Potential Serum Biomarker for Duchenne Muscular Dystrophy.	DAG1 DMD UTRN	3.71e-08	3	117	3	27854211
Pubmed	Utrophin A is essential in mediating the functional adaptations of mdx mouse muscle following chronic AMPK activation.	DAG1 DMD UTRN	3.71e-08	3	117	3	25324540
Pubmed	Phosphorylation within the cysteine-rich region of dystrophin enhances its association with β-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting.	DAG1 DMD UTRN	3.71e-08	3	117	3	25082828
Pubmed	Dystroglycan mRNA expression during normal and mdx mouse embryogenesis: a comparison with utrophin and the apo-dystrophins.	DAG1 DMD UTRN	3.71e-08	3	117	3	8589441
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1 DMD	1.48e-07	4	117	3	8954775
Pubmed	Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.	DAG1 DMD UTRN	1.48e-07	4	117	3	17389230
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SART3 PPFIA4 SPTA1 SPTB FKBP9 RTN3 CUL5 CYFIP1 DST NF1 SACS HECW2 NISCH MACF1 HADHA DMD AKR1B1 UTRN UNC13A	3.12e-07	1431	117	19	37142655
Pubmed	Dp71 gene disruption alters the composition of the dystrophin-associated protein complex and neuronal nitric oxide synthase expression in the hypothalamic supraoptic and paraventricular nuclei.	DAG1 DMD UTRN	3.69e-07	5	117	3	22493004
Pubmed	Specific disruption of a schwann cell dystrophin-related protein complex in a demyelinating neuropathy.	DAG1 DMD UTRN	3.69e-07	5	117	3	11430802
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SART3 EML4 POLD2 DOCK10 CHD4 HEATR1 LBR COLGALT1 URB1 CYFIP1 DST NF1 SUPV3L1 MACF1 HADHA GCN1 UTRN MED12	6.43e-07	1353	117	18	29467282
Pubmed	Expression of the dystrophin-related protein 2 (Drp2) transcript in the mouse.	DAG1 DMD UTRN	7.37e-07	6	117	3	9245586
Pubmed	Contribution of the different modules in the utrophin carboxy-terminal region to the formation and regulation of the DAP complex.	DAG1 DMD UTRN	7.37e-07	6	117	3	10767429
Pubmed	Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle.	DAG1 DMD UTRN	1.29e-06	7	117	3	1461282
Pubmed	Loss of short dystrophin isoform Dp71 in olfactory ensheathing cells causes vomeronasal nerve defasciculation in mouse olfactory system.	DAG1 DMD UTRN	2.05e-06	8	117	3	18586242
Pubmed	Genetic mapping in the region of the mouse X-inactivation center.	TAF1 DMD TAF1L	2.05e-06	8	117	3	1974879
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	SART3 CHD4 HEATR1 URB1 DST NF1 MACF1 WDR12 HADHA GCN1 UTRN MED12	2.21e-06	653	117	12	22586326
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	DAG1 RTN3 BTAF1 HEATR1 LBR URB1 RPAP1 ATAD1 NISCH TCF25 UGGT2 TIMELESS HADHA GCN1	3.61e-06	942	117	14	31073040
Pubmed	Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.	TAF1 DMD TAF1L	4.38e-06	10	117	3	2055107
Pubmed	Cytoskeletal disruption and small heat shock protein translocation immediately after lengthening contractions.	SPTB DAG1 DMD	4.38e-06	10	117	3	14627610
Pubmed	Interactome Analysis Reveals a Novel Role for RAD6 in the Regulation of Proteasome Activity and Localization in Response to DNA Damage.	SPTA1 OBSCN BTAF1 LBR NISCH GCN1	5.65e-06	131	117	6	28031328
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	SIKE1 XPO4 BTAF1 URB1 RPAP1 UGGT2 TIMELESS GCN1	5.81e-06	285	117	8	32838362
Pubmed	Characterization of a murine gene expressed from the inactive X chromosome.	TAF1 DMD TAF1L	6.00e-06	11	117	3	2034278
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 SLC4A8 ARHGEF28 PPFIA4 RSPRY1 PARP4 FAT2 SACS MACF1 MED12	6.89e-06	493	117	10	15368895
Pubmed	Defining the membrane proteome of NK cells.	ELMOD2 EML4 DOCK10 CHD4 HEATR1 LBR COLGALT1 ITGAX PARP4 NF1 ATAD1 NISCH GCN1 MED12 RUSF1	9.17e-06	1168	117	15	19946888
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SART3 EML4 XPO4 ZYG11B HEATR1 RSPRY1 CYFIP1 CCDC88A NF1 ATAD1 WDCP NISCH UGGT2 GCN1 MUC5AC RUSF1	9.35e-06	1321	117	16	27173435
Pubmed	Rps4 maps near the inactivation center on the mouse X chromosome.	TAF1 DMD TAF1L	1.04e-05	13	117	3	1740345
Pubmed	Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.	TAF1 DMD TAF1L	1.04e-05	13	117	3	8012115
Pubmed	XIST and the mapping of the X chromosome inactivation centre.	TAF1 DMD TAF1L	1.04e-05	13	117	3	1772416
Pubmed	The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.	TAF1 DMD TAF1L	1.04e-05	13	117	3	7805729
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	1.12e-05	2	117	2	10525423
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	1.12e-05	2	117	2	28790199
Pubmed	α-Dystroglycan hypoglycosylation affects cell migration by influencing β-dystroglycan membrane clustering and filopodia length: A multiscale confocal microscopy analysis.	DAG1 DMD	1.12e-05	2	117	2	28572004
Pubmed	Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis.	LBR TM7SF2	1.12e-05	2	117	2	16784888
Pubmed	Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.	DMD UTRN	1.12e-05	2	117	2	25859846
Pubmed	Structure of a WW domain containing fragment of dystrophin in complex with beta-dystroglycan.	DAG1 DMD	1.12e-05	2	117	2	10932245
Pubmed	G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.	DMD UTRN	1.12e-05	2	117	2	7731967
Pubmed	Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.	DMD UTRN	1.12e-05	2	117	2	16710609
Pubmed	HEM dysplasia and ichthyosis are likely laminopathies and not due to 3beta-hydroxysterol Delta14-reductase deficiency.	LBR TM7SF2	1.12e-05	2	117	2	17403717
Pubmed	Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.	DMD UTRN	1.12e-05	2	117	2	30672725
Pubmed	A deletional frameshift mutation of the beta-spectrin gene associated with elliptocytosis in spectrin Tokyo (beta 220/216).	SPTA1 SPTB	1.12e-05	2	117	2	1391962
Pubmed	Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.	DMD UTRN	1.12e-05	2	117	2	7962191
Pubmed	Disruption of sarcolemmal dystrophin and beta-dystroglycan may be a potential mechanism for myocardial dysfunction in severe sepsis.	DAG1 DMD	1.12e-05	2	117	2	20142806
Pubmed	Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?	DMD UTRN	1.12e-05	2	117	2	8021701
Pubmed	Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.	DMD UTRN	1.12e-05	2	117	2	26974331
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.12e-05	2	117	2	11002341
Pubmed	Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.	DMD UTRN	1.12e-05	2	117	2	28453658
Pubmed	A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.	DMD UTRN	1.12e-05	2	117	2	11801396
Pubmed	Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.	DMD UTRN	1.12e-05	2	117	2	7987307
Pubmed	Comparative analysis of the human dystrophin and utrophin gene structures.	DMD UTRN	1.12e-05	2	117	2	11861579
Pubmed	Distinct mechanical properties in homologous spectrin-like repeats of utrophin.	DMD UTRN	1.12e-05	2	117	2	30914715
Pubmed	Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.	DMD UTRN	1.12e-05	2	117	2	22284942
Pubmed	Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.	DMD UTRN	1.12e-05	2	117	2	17889902
Pubmed	Molecular evolution of the CYP2D subfamily in primates: purifying selection on substrate recognition sites without the frequent or long-tract gene conversion.	CYP2D7 CYP2D6	1.12e-05	2	117	2	25808902
Pubmed	Chaperone activity and prodan binding at the self-associating domain of erythroid spectrin.	SPTA1 SPTB	1.12e-05	2	117	2	15492010
Pubmed	Beta spectrin kissimmee: a spectrin variant associated with autosomal dominant hereditary spherocytosis and defective binding to protein 4.1.	SPTA1 SPTB	1.12e-05	2	117	2	8102379
Pubmed	Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype: a role for the CYP2D6*35 allele in ultrarapid metabolism?	CYP2D7 CYP2D6	1.12e-05	2	117	2	11207030
Pubmed	Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.	DMD UTRN	1.12e-05	2	117	2	35557546
Pubmed	Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.	DMD UTRN	1.12e-05	2	117	2	37626761
Pubmed	Beta-spectrin Promiss-ao: a translation initiation codon mutation of the beta-spectrin gene (ATG --> GTG) associated with hereditary spherocytosis and spectrin deficiency in a Brazilian family.	SPTA1 SPTB	1.12e-05	2	117	2	9414314
Pubmed	Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.	DMD UTRN	1.12e-05	2	117	2	15565469
Pubmed	The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.	DMD UTRN	1.12e-05	2	117	2	26516677
Pubmed	Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.	DMD UTRN	1.12e-05	2	117	2	22209498
Pubmed	Mutation of a highly conserved residue of betaI spectrin associated with fatal and near-fatal neonatal hemolytic anemia.	SPTA1 SPTB	1.12e-05	2	117	2	9005995
Pubmed	Identification of the molecular defect in the erythrocyte membrane skeleton of some kindreds with hereditary spherocytosis.	SPTA1 SPTB	1.12e-05	2	117	2	7104494
Pubmed	A genetic defect in the binding of protein 4.1 to spectrin in a kindred with hereditary spherocytosis.	SPTA1 SPTB	1.12e-05	2	117	2	6215583
Pubmed	A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.	DMD UTRN	1.12e-05	2	117	2	37108685
Pubmed	Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.	DMD UTRN	1.12e-05	2	117	2	10694796
Pubmed	Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.	TAF1 TAF1L	1.12e-05	2	117	2	38804708
Pubmed	Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.	DMD UTRN	1.12e-05	2	117	2	24337461
Pubmed	Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.	DMD UTRN	1.12e-05	2	117	2	11297940
Pubmed	Spectrin Nice (beta 220/216): a shortened beta-chain variant associated with an increase of the alpha I/74 fragment in a case of elliptocytosis.	SPTA1 SPTB	1.12e-05	2	117	2	3580577
Pubmed	Recurrent fatal hydrops fetalis associated with a nucleotide substitution in the erythrocyte beta-spectrin gene.	SPTA1 SPTB	1.12e-05	2	117	2	7883966
Pubmed	Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.	DMD UTRN	1.12e-05	2	117	2	22388933
Pubmed	Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.	DMD UTRN	1.12e-05	2	117	2	25642938
Pubmed	Highly accurate two-gene classifier for differentiating gastrointestinal stromal tumors and leiomyosarcomas.	PRUNE2 OBSCN	1.12e-05	2	117	2	17360660
Pubmed	Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.	DMD UTRN	1.12e-05	2	117	2	15703201
Pubmed	Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.	DMD UTRN	1.12e-05	2	117	2	25941878
Pubmed	Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.	TAF1 TAF1L	1.12e-05	2	117	2	22842574
Pubmed	Exogenous Dp71 restores the levels of dystrophin associated proteins but does not alleviate muscle damage in mdx mice.	DAG1 DMD	1.12e-05	2	117	2	7894483
Pubmed	Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.	DMD UTRN	1.12e-05	2	117	2	9297964
Pubmed	Characterization of the common genetic defect in humans deficient in debrisoquine metabolism.	CYP2D7 CYP2D6	1.12e-05	2	117	2	3123997
Pubmed	The WW domain of dystrophin requires EF-hands region to interact with beta-dystroglycan.	DAG1 DMD	1.12e-05	2	117	2	10355629
Pubmed	SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.	DMD UTRN	1.12e-05	2	117	2	25652448
Pubmed	Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.	DMD UTRN	1.12e-05	2	117	2	28785010
Pubmed	Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.	DMD UTRN	1.12e-05	2	117	2	16307000
Pubmed	Dystroglycan Mediates Clustering of Essential GABAergic Components in Cerebellar Purkinje Cells.	DAG1 DMD	1.12e-05	2	117	2	32982691
Pubmed	Spectrin Cosenza: a novel beta chain variant associated with Sp alphaI/74 hereditary elliptocytosis.	SPTA1 SPTB	1.12e-05	2	117	2	9163587
Pubmed	Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.	DMD UTRN	1.12e-05	2	117	2	21949353
Pubmed	Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.	DMD UTRN	1.12e-05	2	117	2	23097179
Pubmed	The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.	DMD UTRN	1.12e-05	2	117	2	15501597
Pubmed	Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.	TAF1 TAF1L	1.12e-05	2	117	2	27571988
Pubmed	Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.	DMD UTRN	1.12e-05	2	117	2	11257121
Pubmed	Identification of three novel spectrin alpha I/74 mutations in hereditary elliptocytosis: further support for a triple-stranded folding unit model of the spectrin heterodimer contact site.	SPTA1 SPTB	1.12e-05	2	117	2	8018926
Pubmed	Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.	TAF1 TAF1L	1.12e-05	2	117	2	34403156
Pubmed	Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.	DMD UTRN	1.12e-05	2	117	2	18973234
Pubmed	Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.	DMD UTRN	1.12e-05	2	117	2	27881412
Pubmed	Lack of dystrophin leads to the selective loss of superior cervical ganglion neurons projecting to muscular targets in genetically dystrophic mdx mice.	DAG1 DMD	1.12e-05	2	117	2	16023353
Pubmed	Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.	DMD UTRN	1.12e-05	2	117	2	20625423
Pubmed	Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.	DMD UTRN	1.12e-05	2	117	2	29065908
Cytoband	11q22.3	CWF19L2 CUL5 ALKBH8	1.98e-04	44	117	3	11q22.3
GeneFamily	UNC13 homologs	UNC13D UNC13A	1.12e-04	4	79	2	836
GeneFamily	IZUMO family	IZUMO4 IZUMO1	1.12e-04	4	79	2	56
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTB	3.90e-04	7	79	2	1113
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	5.19e-04	8	79	2	939
GeneFamily	EF-hand domain containing	SPTA1 FKBP9 PLCD4 DST MACF1	2.71e-03	219	79	5	863
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DMD UTRN	2.76e-03	18	79	2	91
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCD4 PLCB4	3.07e-03	19	79	2	832
GeneFamily	DNA polymerases	POLD2 REV3L	4.49e-03	23	79	2	535
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EML4 PPFIA4 DOCK10 CHD4 CCDC88A MACF1 UTRN	5.79e-07	184	117	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CWF19L2 EML4 BTAF1 TCF25 MACF1 IFI44L UTRN	9.80e-07	199	117	7	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PPFIA4 SPTB ITGAX FAT2 SKOR1	8.17e-06	180	117	6	6ac62bf1251978c8c12e715f7b73144fca619794
ToppCell	Control-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	ARHGEF28 RTN3 CCDC88A DST MME AKR1B1	9.55e-06	185	117	6	85cb81759589a26d83676cffbf2bc37399683c10
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	EML4 DOCK10 BTAF1 NF1 MACF1 UTRN	1.05e-05	188	117	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PRUNE2 ARHGEF28 DOCK10 MACF1 PLCB4 DMD	1.05e-05	188	117	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Control / Disease state, Lineage and Cell class	ARHGEF28 RTN3 CCDC88A DST MME AKR1B1	1.08e-05	189	117	6	937e876122bc4b94372a4104e9c1a9068c232018
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 ARHGEF28 DOCK10 MACF1 PLCB4 DMD	1.08e-05	189	117	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	ARHGEF28 EML4 RTN3 DST MME AKR1B1	1.11e-05	190	117	6	2592765016f291565697265800a232b2edef3792
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 FKBP9 COLGALT1 CYFIP1 NISCH PROS1	1.11e-05	190	117	6	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	ARHGEF28 EML4 RTN3 CCDC88A DST MME	1.11e-05	190	117	6	9fc763d65470ba8858b973689c4d4358faab7dd3
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	DOCK10 XPO4 HEATR1 LBR URB1 MACF1	1.14e-05	191	117	6	9454f642c3621370fa23640b631301346b300950
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	ARHGEF28 EML4 RTN3 CCDC88A DST MME	1.14e-05	191	117	6	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|lung / Disease (COVID-19 only), tissue and cell type	ATG7 EML4 DOCK10 ITGAX CCDC88A MME	1.14e-05	191	117	6	dab953682b8c9ed680a799161f837f792a7e4f33
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D175\|Adult / Lineage, Cell type, age group and donor	ABCA1 ATG7 EML4 COLGALT1 ITGAX CCDC88A	1.18e-05	192	117	6	733491e932350e3c216a626cc49c3cd3fe970a82
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RGSL1 SPTA1 BNC1 ABCC12 TAF1L TJP3	1.21e-05	193	117	6	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	Children_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABCA1 ATG7 EML4 ITGAX CYFIP1 CCDC88A	1.29e-05	195	117	6	9d649ac7d2af313481069c95349efc0c68449e2b
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAL3ST4 CYFIP1 DST MACF1 KLHDC8B PROS1	1.29e-05	195	117	6	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 CHD4 REV3L DST NISCH MACF1	1.29e-05	195	117	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	ABCA1 EML4 DOCK10 COLGALT1 ITGAX CCDC88A	1.29e-05	195	117	6	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 CHD4 REV3L DST NISCH MACF1	1.29e-05	195	117	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 FKBP9 REV3L NISCH MACF1 UTRN	1.33e-05	196	117	6	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA1 FKBP9 REV3L NISCH MACF1 UTRN	1.33e-05	196	117	6	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 COLGALT1 ITGAX CCDC88A IFI44L MME	1.40e-05	198	117	6	e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 COLGALT1 ITGAX CCDC88A IFI44L MME	1.40e-05	198	117	6	0baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCell	ASK440\|World / Donor, Lineage and Cell class of Lung cells from Dropseq	ARHGEF28 RTN3 ZYG11B COLGALT1 PARP4 CCDC88A	1.40e-05	198	117	6	f3ed6efd521c691debae32a803972bed5d069332
ToppCell	COVID-19-lung\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA1 DOCK10 ITGAX IFI44L UTRN SMURF2	1.44e-05	199	117	6	155b03b859157013e9142e9248551369127d9204
ToppCell	Parenchyma_Control_(B.)-Immune-TX-TRAM-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	ARHGEF28 DOCK10 CCDC88A IFI44L MME AKR1B1	1.49e-05	200	117	6	7c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c09-SLC4A10\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ITFG2 SPTB PLCD4 ZYG11B SACS	4.78e-05	150	117	5	c2c51a3230c978e2fdb1b3ae14193d4014431b25
ToppCell	Control-Neu_1\|Control / 5 Neutrophil clusters in COVID-19 patients	UNC13D PARP4 MME	5.35e-05	28	117	3	eb8d8303c1a8f8f8cf9f8c2180406c06624690af
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|356C / Donor, Lineage, Cell class and subclass (all cells)	IZUMO4 ELMOD2 CYFIP1 ALKBH8 TJP3	6.89e-05	162	117	5	2f19539c455d1e5d514725845234c7547020e6ad
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	IZUMO4 ELMOD2 ITFG2 ALKBH8 TJP3	7.30e-05	164	117	5	d6806deabf5f5c355934387be2baae125ac33fb8
ToppCell	PND14-Immune-Immune_Myeloid-DC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC4A8 PPFIA4 DOCK10 ITGAX CCDC88A	8.89e-05	171	117	5	8772d6349db24de47f089df2032a80345db7177f
ToppCell	droplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 ABCA1 GAL3ST4 ITGAX DST	9.13e-05	172	117	5	7295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPR65 DOCK10 ITGAX CKMT2 ALKBH8	9.64e-05	174	117	5	ccc79febfcf588d8294ffc712338be96de8a5033
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPFIA4 DOCK10 ITGAX TIMELESS FAM149A	9.64e-05	174	117	5	6688424fc4e40c3c4a89669a2bc79369a726f1e6
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DPP10 LBR SACS SMURF2	1.02e-04	176	117	5	33323c97afe509147956b8df9f92ca6b0537e604
ToppCell	COVID-19-lung-MAST\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC4A8 GPR65 DOCK10 ITGAX PARP4	1.02e-04	176	117	5	473c45a381ca109207d66ed1635668b391ea0e1f
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	MEIKIN RMI2 GAL3ST4 COLGALT1 WDR12	1.02e-04	176	117	5	4bba41ebf9dd187c8705a6997ed039878de62b4e
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages\|lymph-node_spleen / Manually curated celltypes from each tissue	XPO4 GAL3ST4 CYFIP1 UGGT2 KLHDC8B	1.05e-04	177	117	5	52c2ba74a8605260a2623e7d151286e504ac4d19
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 DOCK10 ITGAX TIMELESS FAM149A	1.05e-04	177	117	5	3cb96d7d56c9ff90f1f8a6caaf49e580e2524c7d
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 DOCK10 ITGAX TIMELESS FAM149A	1.07e-04	178	117	5	8c5e9fab7b55a654ccaabf2c4d02397399d94616
ToppCell	facs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPFIA4 DOCK10 ITGAX CCDC88A TIMELESS	1.10e-04	179	117	5	55fde77dae7f9e7f3431c3185d14212a25af83df
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPFIA4 DOCK10 ITGAX TIMELESS FAM149A	1.10e-04	179	117	5	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABCA1 COLGALT1 ITGAX CCDC88A CCNB3	1.19e-04	182	117	5	ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 COLGALT1 CCDC88A MME AKR1B1	1.22e-04	183	117	5	103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DPP10 FRMPD1 IGFBP1 SOHLH1 UNC13A	1.22e-04	183	117	5	8820cfed27b292bc0bc9cde4005219ed41900552
ToppCell	droplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EML4 HEATR1 COLGALT1 METTL1	1.22e-04	183	117	5	92ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCell	droplet-Marrow-nan-3m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 EML4 HEATR1 COLGALT1 METTL1	1.22e-04	183	117	5	24db9cc717e651586317c6a8e03a3401651273c1
ToppCell	facs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 DOCK10 ITGAX TIMELESS FAM149A	1.22e-04	183	117	5	107cc756c45d6e92181659868d91188814dae66d
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ABCA1 ZYG11B REV3L ADAMTSL3 UTRN	1.25e-04	184	117	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	RTN3 CCDC88A DST TIMELESS MME	1.25e-04	184	117	5	7fd0b227c3750ffb80e41e92c60fcce46656be14
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	ae966929fb5bbb08ffcbac76cb21941638727f55
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	3beebaa92275086b1fae5f8c0c3d54016c5ba2aa
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	ceff11cfa679147ccfd0a0f8079e697a6bea34d9
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COLGALT1 ITGAX DST PROS1	1.29e-04	185	117	5	afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COLGALT1 ITGAX DST PROS1	1.29e-04	185	117	5	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	DOCK10 HEATR1 LBR URB1 MACF1	1.29e-04	185	117	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	BAL-Severe-Myeloid-Macrophage\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	9aea5ed8f9cee5ee933891203aac7adb85d68201
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EML4 DOCK10 CHD4 CCDC88A MACF1	1.29e-04	185	117	5	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	42939b294ea3e871274d8b73124c850dc1904fd2
ToppCell	Severe_COVID-19-Myeloid-transitional_Macro\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	f7ef0d7740b4cfedc38846e802898c402dc411fd
ToppCell	facs-Lung-24m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPFIA4 DOCK10 ITGAX TIMELESS FAM149A	1.29e-04	185	117	5	ed7b26bdebfd0df2b4f5020a855a052d94ae7219
ToppCell	BAL-Severe-Myeloid-Macrophage-transitional_Macro\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RTN3 GAL3ST4 CYFIP1 DST AKR1B1	1.29e-04	185	117	5	7a3612520ae4f0cd61480eadba31eecce001419d
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COLGALT1 ITGAX DST PROS1	1.32e-04	186	117	5	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 COLGALT1 ITGAX DST PROS1	1.32e-04	186	117	5	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	DOCK10 HEATR1 LBR URB1 MACF1	1.32e-04	186	117	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 DOCK10 COLGALT1 ITGAX DST	1.35e-04	187	117	5	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	droplet-Marrow-BM-1m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIA4 DOCK10 COLGALT1 CCDC88A PROS1	1.35e-04	187	117	5	028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 DOCK10 COLGALT1 ITGAX DST	1.35e-04	187	117	5	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	droplet-Marrow-nan-21m-Myeloid-Cd4_positive_Macrophages\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 FKBP9 COLGALT1 METTL1 WDR12	1.39e-04	188	117	5	f94dc08948a823f47882aa0714b9a60de4ff85d5
ToppCell	droplet-Marrow-nan-21m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 FKBP9 COLGALT1 METTL1 WDR12	1.39e-04	188	117	5	7c67330c36696a7772364af67c6df4e6406fa742
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 DOCK10 COLGALT1 ITGAX DST	1.42e-04	189	117	5	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FKBP9 FANCC MACF1 UGGT2 MME	1.42e-04	189	117	5	dc5164591dea45b420798b94dda211be03daa70c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 PPFIA4 SPTB FAT2 SKOR1	1.42e-04	189	117	5	f57200c93d39c9bce1adba0a6a1c178c028dd86b
ToppCell	IPF-Myeloid-Macrophage_Alveolar\|IPF / Disease state, Lineage and Cell class	RTN3 CCDC88A DST MME AKR1B1	1.46e-04	190	117	5	e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCell	TCGA-Kidney-Primary_Tumor\|TCGA-Kidney / Sample_Type by Project: Shred V9	GAL3ST4 COLGALT1 ITGAX RBCK1 CCM2	1.46e-04	190	117	5	773c4575d22483d89a54c8db0e09905deed0d088
ToppCell	TCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma\|TCGA-Kidney / Sample_Type by Project: Shred V9	GAL3ST4 COLGALT1 ITGAX RBCK1 CCM2	1.46e-04	190	117	5	e3696e7542424c03d0a41136b10729a3dd09549a
ToppCell	COPD-Myeloid-Macrophage_Alveolar\|COPD / Disease state, Lineage and Cell class	RTN3 COLGALT1 CCDC88A DST MME	1.46e-04	190	117	5	006e31606d637033bc81333816ee332773d36b08
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPTB OBSCN ADAMTSL3 CKMT2 DMD	1.46e-04	190	117	5	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	PND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	FKBP9 FANCC MACF1 UGGT2 MME	1.46e-04	190	117	5	1196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 DOCK10 COLGALT1 ITGAX DST	1.46e-04	190	117	5	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	facs-Marrow-KLS-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC4A8 COLGALT1 ITGAX TIMELESS FAM149A	1.46e-04	190	117	5	c03c735a0ed850bf460a1847f5e2dd61753e577d
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.49e-04	191	117	5	2b10a73c5d80e83d67a7121fb004a1aa86a537ef
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.49e-04	191	117	5	02e1ae144da7274171e055356d10e8d175c5347f
ToppCell	Severe_COVID-19-Myeloid-TRAM3\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.49e-04	191	117	5	05867b96199a46a415848409130697c810d18937
ToppCell	BAL-Severe-Myeloid-TRAM\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.49e-04	191	117	5	4c4f50a502e3f6768a89df686fa2830b83b8b33f
ToppCell	COVID-19-lung-Macrophage_PPARGhi_CD5Lhi\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ATG7 EML4 DOCK10 ITGAX CCDC88A	1.53e-04	192	117	5	bcfb9c005166bc0b4f8ee2dfc0c1540e8bf0e1ff
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.53e-04	192	117	5	34505a13b8a47c9286c560122fa7861b9c331a08
ToppCell	COVID-19-Myeloid-TRAM1\|COVID-19 / Condition, Lineage and Cell class	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.53e-04	192	117	5	52b8578699325b0d35a2d3ba36772096130ccc0c
ToppCell	BAL-Severe-Myeloid-TRAM-TRAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ARHGEF28 DST MME AKR1B1 KLHDC8B	1.53e-04	192	117	5	57c1410ebf90c230993e065eb78385daa3360960
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 CYFIP1 DST MACF1 PROS1	1.57e-04	193	117	5	06b65110db974f4ef90d3511ff34428976a52c9c
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D122\|Adult / Lineage, Cell type, age group and donor	EML4 COLGALT1 ITGAX CCDC88A MME	1.57e-04	193	117	5	cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRMPD1 DOCK10 ADAMTSL3 UTRN MYO16	1.57e-04	193	117	5	294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCell	facs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 CYFIP1 DST MACF1 PROS1	1.57e-04	193	117	5	9c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell	COVID-19-Myeloid-TRAM1\|Myeloid / Condition, Lineage and Cell class	ARHGEF28 DST MME AKR1B1 PROS1	1.57e-04	193	117	5	6e6a7f4e50c8ae70bc187b9ce77140a7049dd288
ToppCell	facs-Brain_Myeloid-Hippocampus-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 CYFIP1 DST MACF1 PROS1	1.57e-04	193	117	5	a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 COLGALT1 CCDC88A MME KLHDC8B	1.57e-04	193	117	5	50c2832de75b6469f649355c6b9a75e910d32db3
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	EML4 BTAF1 MACF1 IFI44L UTRN	1.57e-04	193	117	5	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 COLGALT1 CCDC88A MME KLHDC8B	1.57e-04	193	117	5	222829c30ebe47f0ed1e035897e3cd4be10b2a11
Drug	methyl 9-octadecenoate	CYP2D7 CYP2D6 SPTB LBR RFX4 CKMT2 DMD UTRN	1.16e-07	112	117	8	CID000008202
Drug	plakin	SPTA1 SPTB DST MACF1 DMD UTRN	4.12e-06	82	117	6	CID000018752
Drug	Decamethonium bromide [541-22-0]; Down 200; 9.6uM; HL60; HT_HG-U133A	PPFIA4 NAGLU DOCK10 EML3 RPAP1 TM7SF2 TAF1 RUSF1	8.94e-06	199	117	8	2933_DN
Drug	chlorphentermine	SPTB DAG1 PLCD4 PLCB4	9.07e-06	26	117	4	CID000010007
Drug	benzaldehyde oxime	CYP2D7 CYP2D6 AKR1B1	1.55e-05	10	117	3	CID000012143
Drug	20,25-diazacholesterol	SPTB LBR TM7SF2	2.12e-05	11	117	3	CID000009402
Drug	cupreidine	CYP2D7 CYP2D6	2.62e-05	2	117	2	CID000051196
Drug	ADR-033	MME DMD	2.62e-05	2	117	2	CID000005586
Drug	3-methoxyphenethylamine	CYP2D7 CYP2D6	2.62e-05	2	117	2	CID000074866
Drug	lead azide	BNC1 MNT	2.62e-05	2	117	2	CID000061600
Drug	S 105	SPTB DAG1 DMD	2.81e-05	12	117	3	CID000031154
Drug	M-NR	CYP2D7 CYP2D6 MRS2 MNT	3.07e-05	35	117	4	CID003000480
Drug	AC1L1JL9	CYP2D7 CYP2D6 MNT	3.64e-05	13	117	3	CID000005091
Drug	testosterone enanthate	PRUNE2 SART3 CHD4 ADAMTSL3 FANCC CUL5 TCF25 MACF1 IFI44L HADHA PROS1 FAM149A	4.14e-05	575	117	12	ctd:C004648
Drug	Acetohexamide [968-81-0]; Up 200; 12.4uM; PC3; HT_HG-U133A	SIKE1 EML4 EML3 URB1 CCDC88A IFI44L UTRN	6.17e-05	192	117	7	1829_UP
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	PAPPA2 EML4 DOCK10 CCDC88A NF1 TAF1 UTRN	6.80e-05	195	117	7	3721_DN
Drug	Liothyronine [6893-02-3]; Down 200; 6.2uM; MCF7; HT_HG-U133A	SLC4A8 EML3 NF1 TAF1 MUC5AC UTRN TJP3	7.02e-05	196	117	7	3324_DN
Drug	Neomycin sulfate [1405-10-3]; Up 200; 4.2uM; MCF7; HT_HG-U133A	PAPPA2 PRUNE2 ABCA1 SPTB FRMPD1 TAF1 FAM149A	7.25e-05	197	117	7	2229_UP
Drug	Nifenazone [2139-47-1]; Down 200; 13uM; MCF7; HT_HG-U133A	SLC4A8 ITFG2 EML3 NF1 RPAP1 RUSF1 TJP3	7.49e-05	198	117	7	6016_DN
Drug	Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; PC3; HT_HG-U133A	EML3 CCDC88A NF1 TM7SF2 IFI44L UTRN RUSF1	7.73e-05	199	117	7	5788_DN
Drug	2,4,6-trimethylbenzaldoxime	CYP2D7 CYP2D6	7.83e-05	3	117	2	CID000283782
Drug	O-demethyl encainide	CYP2D7 CYP2D6	7.83e-05	3	117	2	CID000054736
Drug	Mfpa	TAF1 TAF1L	7.83e-05	3	117	2	CID003035615
Drug	B234	DAG1 DMD	7.83e-05	3	117	2	CID006435969
Drug	chlorpromazine N-oxide	CYP2D7 CYP2D6	7.83e-05	3	117	2	CID000443037
Drug	Wang resin	SPTA1 DST	7.83e-05	3	117	2	CID000070043
Drug	ddTTP	POLD2 DAG1 REV3L AKR1B1 MNT	8.22e-05	86	117	5	CID000065051
Drug	AC1L1B3Z	DPP10 FANCC CCDC88A DST	8.39e-05	45	117	4	CID000001273
Drug	AC1NV8O5	CYP2D7 CYP2D6 LBR DST	8.39e-05	45	117	4	CID005473386
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	EML4 EML3 DMD UTRN	1.09e-05	36	113	4	DOID:11723 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	CYP2D6 FRMPD1 OBSCN CUL5 ALKBH8 NF1 WDCP NISCH MROH7 MACF1 TIMELESS MME DMD MED12 RUSF1	1.53e-05	1074	113	15	C0006142
Disease	Duchenne muscular dystrophy (is_implicated_in)	DAG1 DMD	4.35e-05	3	113	2	DOID:11723 (is_implicated_in)
Disease	muscular dystrophy (implicated_via_orthology)	DAG1 DMD UTRN	6.92e-05	21	113	3	DOID:9884 (implicated_via_orthology)
Disease	Hereditary elliptocytosis	SPTA1 SPTB	8.68e-05	4	113	2	cv:C0013902
Disease	solanidine measurement	CYP2D7 CYP2D6	8.68e-05	4	113	2	EFO_0800966
Disease	testosterone measurement	CYP2D7 EML4 RMI2 DAG1 UNC13D URB1 NF1 ZNF655 NISCH MACF1 MME AKR1B1 UTRN MED12 MYO16	1.07e-04	1275	113	15	EFO_0004908
Disease	hereditary spherocytosis (is_implicated_in)	SPTA1 SPTB	1.44e-04	5	113	2	DOID:12971 (is_implicated_in)
Disease	Duchenne muscular dystrophy (is_marker_for)	DAG1 DMD	1.44e-04	5	113	2	DOID:11723 (is_marker_for)
Disease	Hereditary spherocytosis	SPTA1 SPTB	1.44e-04	5	113	2	cv:C0037889
Disease	Anemia, hereditary spherocytic hemolytic	SPTA1 SPTB	1.44e-04	5	113	2	C0221409
Disease	reticulocyte measurement	ABCA1 ARHGEF28 SPTA1 SPTB RMI2 FKBP9 ITGAX CUL5 CCM2 NISCH TCF25 AKR1B1 MED12	2.00e-04	1053	113	13	EFO_0010700
Disease	3-hydroxyisobutyrate measurement	LVRN GPR65	2.16e-04	6	113	2	EFO_0010983
Disease	Elliptocytosis, Hereditary	SPTA1 SPTB	2.16e-04	6	113	2	C0013902
Disease	Colorectal Carcinoma	ABCA1 OBSCN ADAMTSL3 NF1 RPAP1 ATAD1 SACS CCNB3 DMD PROS1	3.75e-04	702	113	10	C0009402
Disease	Hereditary spherocytosis	SPTA1 SPTB	4.01e-04	8	113	2	C0037889
Disease	reticulocyte count	ABCA1 ARHGEF28 SPTA1 SPTB RMI2 FKBP9 ITGAX CCM2 NISCH TCF25 AKR1B1 MED12	6.77e-04	1045	113	12	EFO_0007986
Disease	nervous system disease (implicated_via_orthology)	ATG7 SKOR1	9.36e-04	12	113	2	DOID:863 (implicated_via_orthology)
Disease	Prostatic Neoplasms	NAGLU DAG1 UNC13D MME ZBED1 TAF1L MED12 TJP3	2.59e-03	616	113	8	C0033578
Disease	Malignant neoplasm of prostate	NAGLU DAG1 UNC13D MME ZBED1 TAF1L MED12 TJP3	2.59e-03	616	113	8	C0376358
Disease	Alzheimer disease	ABCA1 SLC4A8 MEIKIN RBCK1 WDR12 MME MYO16	2.69e-03	485	113	7	MONDO_0004975
Disease	PR interval	EML4 OBSCN DAG1 XPO4 RFX4 KIAA1755 MACF1	3.01e-03	495	113	7	EFO_0004462
Disease	otitis media (implicated_via_orthology)	NAGLU NISCH	3.19e-03	22	113	2	DOID:10754 (implicated_via_orthology)
Disease	pars opercularis volume measurement	CWF19L2 ZNF773	3.19e-03	22	113	2	EFO_0010319
Disease	unipolar depression, response to selective serotonin reuptake inhibitor	CYP2D7 CYP2D6	3.80e-03	24	113	2	EFO_0003761, EFO_0005658

Protein segments in the cluster

Peptide	Gene	Start	Entry
WLTLDSQVIMADSEI	UNC13A	96	Q9UPW8
DSDNLQHEELLMKLW	ELMOD2	121	Q8IZ81
ISADSEIEENMVEWL	CUL5	466	Q93034
MLLESVDWTEDTDNQ	ALKBH8	151	Q96BT7
HNVLFDMLTVEEHIW	ABCA1	981	O95477
VLDHWSIMTSEEEVA	BNC1	151	Q01954
WDRMISDISSDIEAL	CCM2	421	Q9BSQ5
NVLTEWLAATDMELT	DMD	1581	P11532
PEMQVSDSDHDWVIL	LVRN	636	Q6Q4G3
SDSDHDWVILNLNMT	LVRN	641	Q6Q4G3
HIDWDSVLIDMDNVI	DPP10	581	Q8N608
TNILDTWAAMEELVD	AKR1B1	136	P15121
DWLVEVQVSFEMTHE	CCNB3	1166	Q8WWL7
EAMTAVDTEAVWLLQ	NAGLU	336	P54802
HTVPLEENLESWSEM	MROH7	366	Q68CQ1
VIHSADITFQMLEDW	RFX4	336	Q33E94
ELNQEAVWMDVEVSH	ITGAX	976	P20702
WNEEALLTTMDIIHD	LBR	436	Q14739
IMEDVVDSSLWSDLS	ARHGEF28	806	Q8N1W1
SLQWMKDNDIHDILD	HECW2	1356	Q9P2P5
WILTDHILETKEASM	CYFIP1	646	Q7L576
WLSLSMDTVEDTLEA	KLHL34	91	Q8N239
EVFDHVWTNMVELLE	FAM149A	456	A5PLN7
LLDEESQMIWSVESN	MYO16	851	Q9Y6X6
LEAAIHQVSDWMEQE	KIAA1755	846	Q5JYT7
GEDEVELMNWLNEVH	DST	5616	Q03001
VEDAQMHTVTIWLTV	RBCK1	61	Q9BYM8
VWVTHEEMETLETST	PPFIA4	911	O75335
MEVTTRLTWNDENHL	IFI44L	1	Q53G44
DWENQLEASMHSVLS	DAG1	41	Q14118
QSMDESLHLGWELEQ	CCDC88A	421	Q3V6T2
SSMEDHLEILEWTLR	POLD2	356	P49005
EWHSILVEEMDASIR	FAT2	3851	Q9NYQ8
MAPSEEDHSILWDAI	IGFBP1	141	P08833
AATLLDEDIWEEIQM	CWF19L2	721	Q2TBE0
FIQTLDDLTWMDAET	MME	451	P08473
MNLESSLEEDHRIFW	MRS2	361	Q9HD23
LEHDMEEINARWNTL	MACF1	1441	O94854
QHALEELMSWLTHTE	MACF1	2356	O94854
ELMSWLTHTEELLDA	MACF1	2361	O94854
HELSQWMDVLEIDRV	MNT	301	Q99583
DGMLDRHEFLTWVLE	MED12	246	Q93074
LEEHMQWKNSTLLDT	MEIKIN	166	A0A087WXM9
SEEEEEWMAQILQIL	GCN1	996	Q92616
VLMWNHDDSLLLELD	MUC5AC	186	P98088
QEVSDLVEMIWAEAL	PARP4	261	Q9UKK3
LAWLDSVFDLVMVAE	GAL3ST4	291	Q96RP7
MEEADKLLWSVQVDH	ITFG2	291	Q969R8
ALEELMSWLTHTEEL	MACF1	6231	Q9UPN3
MSWLTHTEELLDAQR	MACF1	6236	Q9UPN3
DTVHMLLEWLSEAEQ	MACF1	6776	Q9UPN3
DALWHEEAVLTTMDI	TM7SF2	236	O76062
LSHEDEEVEWSLNGM	OBSCN	2581	Q5VST9
VLHFDVLLMDIWNSE	FKBP9	131	O95302
LPENITADTLEHWME	PAPPA2	1691	Q9BXP8
HQETQAAEIWDMSDD	ATG7	686	O95352
ELLTVFMDWISDHHL	CCDC138	356	Q96M89
ELDNLVMVLSDHVIW	DOCK10	1026	Q96BY6
STLEEMIQQHQEWLE	BTAF1	326	O14981
LDELLTEHRMTWDPA	CYP2D6	251	P10635
MESLLELQDILETSW	FRMPD1	1426	Q5SYB0
WDVITLMAHTAEITH	FANCC	506	Q00597
MSRLLHAEEWAEVKE	ATOH1	1	Q92858
KELHSEFSEVMNEIW	HADHA	66	P40939
LDTAETLDMASHTWL	KLHDC8B	46	Q8IXV7
AVEIPSEWHIELMLD	HEATR1	746	Q9H583
EDMILDCELNWHQAS	IZUMO1	176	Q8IYV9
LCVVDDSNEHMLSVW	EML3	376	Q32P44
CIIDDSNEHMLTVWD	EML4	381	Q9HC35
DHNMDNTSTVLREWL	COLGALT1	91	Q8NBJ5
SAQLLEDWGMEDIDH	CHD4	151	Q14839
EWLHDEISMAQDGLD	SART3	151	Q15020
HEEVTQLMLWVLENL	SACS	1006	Q9NZJ4
ALLTDWSDDTMKELH	IZUMO4	51	Q1ZYL8
IWINEEDHTRVISME	CKMT2	261	P17540
LEQTDHWGSTEMELA	MIGA1	441	Q8NAN2
SWVVVKETHEVLDML	RUSF1	416	Q96GQ5
DMHNFTNEILTWDLV	RTN3	331	O95197
VLELVDSMANWVHHT	RSPH6A	531	Q9H0K4
ATDELSHAWEDVKAM	SKOR1	256	P84550
LEDMIIDSLQWDDHR	UTRN	2331	P46939
DFWILAENILSIDEM	RGSL1	106	A5PLK6
ILASSKEMWHSLQED	SOHLH1	116	Q5JUK2
SDNPIHESMWELEVE	RMI2	126	Q96E14
HESMWELEVEDLHRN	RMI2	131	Q96E14
ITLHEMAETDEGWLD	RSPRY1	126	Q96DX4
TKEWSEMINTHSAEE	PLCB4	1021	Q15147
AVTLQAVTHDNEWEM	PRUNE2	2711	Q8WUY3
VTSMDHQERLDQWLS	PLCD4	126	Q9BRC7
LADENFLMVTQLHWE	TAF1L	416	Q8IZX4
NFLMVTQLHWEDDII	TAF1	401	P21675
WISLEEHQDALELIM	SIKE1	91	Q9BRV8
EVHWANLTVSECQEM	SLC4A8	661	Q2Y0W8
MDLEAVHDVLDLYLW	SUPV3L1	626	Q8IYB8
DPFESHTDEMLWQVL	ABCC12	1216	Q96J65
GLWNMVSVEELEHSI	PROS1	381	P07225
KELELWLEHLENTME	URB1	676	O60287
WLEHLENTMEEDKET	URB1	681	O60287
MEDSLLQIQDSWATH	BRINP2	316	Q9C0B6
MHVTWSDIAGLDDVI	ATAD1	86	Q8NBU5
LDELLTEHRMTWDPA	CYP2D7	251	A0A087X1C5
DMELVDPDLHNSLVW	SMURF2	521	Q9HAU4
EEQWSLHVLEIVSLM	TIMELESS	211	Q9UNS1
VQELHSELMWKDFID	ZYG11B	571	Q9C0D3
MLDDLYEDIHWLILV	XPO4	531	Q9C0E2
SLVMSQRWDSNIEEH	REV3L	466	O60673
AEVENEELRHLMWSS	NISCH	1151	Q9Y2I1
IDLSDTDSLQEWINM	NF1	826	P21359
TPTLEQHLMWDDIAI	NF1	2066	P21359
IDWMDEIKAHLLSAE	SPTB	541	P11277
IQEMKEDLVSSWEHI	SPTA1	341	P02549
TPQKEWLHMDTVELE	RPAP1	321	Q9BWH6
RWDMADNEQVLTTEH	YJU2B	121	P13994
LETIFNAVMLWEDET	GPR65	141	Q8IYL9
THEITQLESWEEPFM	ZNF773	61	Q6PK81
MEELTIWEQHTATLS	TJP3	1	O95049
ESLMDLSHLNKWESI	ZNF655	191	Q8N720
HMEAVSSVLWSDAEE	WDR12	256	Q9GZL7
HSSIMWINDLENDDL	UGGT2	441	Q9NYU1
NHHLMLEASEWATIE	ZBED1	381	O96006
IEMLHDSHWILLSAD	WDCP	641	Q9H6R7
HLDMWDLDTVESVRQ	UNC13D	201	Q70J99
KEPATMSWLEENVHE	TCF25	511	Q9BQ70
MSWLEENVHEVLQAV	TCF25	516	Q9BQ70
SKASWETVHMILQEL	TBCEL	136	Q5QJ74
TITDVLELHDWMCTH	METTL1	196	Q9UBP6
VEESMHGEILQVEEW	ADAMTSL3	446	P82987