Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

3.34e-0651403GO:0030156
GeneOntologyMolecularFunctionquaternary ammonium group transmembrane transporter activity

SLC44A4 SLC22A4 SLC22A5

1.44e-04151403GO:0015651
GeneOntologyMolecularFunctionamino-acid betaine transmembrane transporter activity

SLC22A4 SLC22A5

2.90e-0441402GO:0015199
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1E ITGAV RIMBP2 CACNA2D3

3.01e-04461404GO:0005245
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

1.05e-0571423GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

4.87e-05111423GO:0031906
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN3 NLGN2

2.72e-0441422GO:0098983
GeneOntologyCellularComponentstriated muscle myosin thick filament

MYOM1 OBSCN

2.72e-0441422GO:0005863
GeneOntologyCellularComponentmultivesicular body

PGA4 PGA5 PRKAR1A PRKAR1B PGA3

3.36e-04881425GO:0005771
GeneOntologyCellularComponentlate endosome

PGA4 ATP7B PGA5 LDLR OSBPL11 PRKAR1A PRKAR1B RAPGEF2 PGA3

6.36e-043481429GO:0005770
DomainFN3

IL12RB1 MYOM1 OBSCN RIMBP3 TYRO3 PTPRB PTPRS RIMBP3C RIMBP2 OSMR RIMBP3B

3.35e-0719914111PS50853
DomainFN3_dom

IL12RB1 MYOM1 OBSCN RIMBP3 TYRO3 PTPRB PTPRS RIMBP3C RIMBP2 OSMR RIMBP3B

5.47e-0720914111IPR003961
DomainFN3

IL12RB1 MYOM1 OBSCN TYRO3 PTPRB PTPRS RIMBP3C RIMBP2 OSMR RIMBP3B

1.43e-0618514110SM00060
Domain-

FCRL2 IL12RB1 MYOM1 NXPE4 OBSCN PKHD1L1 RIMBP3 TYRO3 CEACAM19 PTPRB PTPRS RIMBP3C ILDR1 RIMBP2 OSMR RIMBP3B CD96

1.08e-05663141172.60.40.10
DomainAspartic_peptidase_N

PGA4 PGA5 PGA3

1.44e-0571413IPR012848
DomainA1_Propeptide

PGA4 PGA5 PGA3

1.44e-0571413PF07966
DomainIg-like_fold

FCRL2 IL12RB1 MYOM1 NXPE4 OBSCN PKHD1L1 RIMBP3 TYRO3 CEACAM19 PTPRB PTPRS RIMBP3C ILDR1 RIMBP2 OSMR RIMBP3B CD96

2.42e-0570614117IPR013783
Domainfn3

IL12RB1 MYOM1 OBSCN TYRO3 PTPRB PTPRS RIMBP2 OSMR

3.21e-051621418PF00041
DomainAspartic_peptidase_A1

PGA4 PGA5 PGA3

4.86e-05101413IPR001461
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

4.86e-05101413IPR033121
DomainAsp

PGA4 PGA5 PGA3

4.86e-05101413PF00026
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

4.86e-05101413PS51767
Domain-

PGA4 PGA5 PGA3

8.82e-051214132.40.70.10
DomainASP_PROTEASE

PGA4 PGA5 PGA3

8.82e-05121413PS00141
DomainAspartic_peptidase_AS

PGA4 PGA5 PGA3

1.14e-04131413IPR001969
DomaincNMP

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

1.21e-04341414SM00100
DomaincNMP_binding

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

1.21e-04341414PF00027
DomaincNMP-bd_dom

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

1.36e-04351414IPR000595
DomainCNMP_BINDING_3

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

1.36e-04351414PS50042
DomaincNMP-bd-like

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

1.88e-04381414IPR018490
DomainSH3

OBSCN SH3BP4 RIMBP3 SH3PXD2A MACF1 RIMBP3C RIMBP2 RIMBP3B

2.39e-042161418PS50002
DomainPeptidase_aspartic_dom

PGA4 PGA5 PGA3

2.65e-04171413IPR021109
DomainSH3_domain

OBSCN SH3BP4 RIMBP3 SH3PXD2A MACF1 RIMBP3C RIMBP2 RIMBP3B

2.70e-042201418IPR001452
DomainSH3_9

SH3BP4 RIMBP3 RIMBP3C RIMBP2 RIMBP3B

3.10e-04781415PF14604
DomainHelicase_C_2

ERCC2 BRIP1

3.36e-0441412PF13307
DomainDEAD_2

ERCC2 BRIP1

3.36e-0441412PF06733
DomainPINIT

PIAS2 PIAS3

3.36e-0441412PS51466
DomainDEAD_2

ERCC2 BRIP1

3.36e-0441412IPR010614
DomainATP-dep_Helicase_C

ERCC2 BRIP1

3.36e-0441412IPR006555
DomainHelicase-like_DEXD_c2

ERCC2 BRIP1

3.36e-0441412IPR006554
DomainPINIT

PIAS2 PIAS3

3.36e-0441412PF14324
DomaincAMP_dep_PK_reg_su

PRKAR1A PRKAR1B

3.36e-0441412IPR012198
DomainDNA_helicase_DNA-repair_Rad3

ERCC2 BRIP1

3.36e-0441412IPR013020
DomainPINIT

PIAS2 PIAS3

3.36e-0441412IPR023321
DomainHELICASE_ATP_BIND_2

ERCC2 BRIP1

3.36e-0441412PS51193
DomainHelic_SF1/SF2_ATP-bd_DinG/Rad3

ERCC2 BRIP1

3.36e-0441412IPR014013
DomainDEXDc2

ERCC2 BRIP1

3.36e-0441412SM00488
DomainHELICc2

ERCC2 BRIP1

3.36e-0441412SM00491
Domain-

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

4.68e-044814142.60.120.10
DomainSH3_2

SH3BP4 RIMBP3 RIMBP3C RIMBP2 RIMBP3B

4.87e-04861415PF07653
DomainSH3_2

SH3BP4 RIMBP3 RIMBP3C RIMBP2 RIMBP3B

4.87e-04861415IPR011511
DomainNlgn

NLGN3 NLGN2

5.58e-0451412IPR000460
DomainRmlC-like_jellyroll

RAPGEF6 PRKAR1A PRKAR1B RAPGEF2

5.91e-04511414IPR014710
DomainGlycoside_hydrolase_SF

GALC CHIA GUSB GAA

6.84e-04531414IPR017853
DomainLCCL

VIT CRISPLD1

8.32e-0461412PS50820
DomainPbH1

FBXO11 PKHD1L1

8.32e-0461412SM00710
DomainRIIa

PRKAR1A PRKAR1B

8.32e-0461412SM00394
DomainLCCL

VIT CRISPLD1

8.32e-0461412SM00603
DomainLCCL

VIT CRISPLD1

8.32e-0461412PF03815
DomainLCCL

VIT CRISPLD1

8.32e-0461412IPR004043
Domain-

VIT CRISPLD1

8.32e-04614122.170.130.20
DomainPbH1

FBXO11 PKHD1L1

8.32e-0461412IPR006626
Domainzf-MIZ

PIAS2 PIAS3

1.16e-0371412PF02891
DomainZF_SP_RING

PIAS2 PIAS3

1.16e-0371412PS51044
DomainRIIa

PRKAR1A PRKAR1B

1.16e-0371412PF02197
DomainHematopoietin_rcpt_Gp130_CS

IL12RB1 OSMR

1.16e-0371412IPR003529
DomainSH3

OBSCN SH3BP4 RIMBP3 SH3PXD2A RIMBP3C RIMBP2 RIMBP3B

1.28e-032161417SM00326
DomainHEMATOPO_REC_L_F2

IL12RB1 OSMR

1.54e-0381412PS01353
DomainPectin_lyase_fold/virulence

FBXO11 PKHD1L1

1.54e-0381412IPR011050
DomainZnf_MIZ

PIAS2 PIAS3

1.54e-0381412IPR004181
DomainOrgcat_transp/SVOP

SLC22A4 SLC22A5

1.97e-0391412IPR004749
Domain-

GALC CHIA GUSB

2.31e-033514133.20.20.80
DomainGlyco_hydro_catalytic_dom

GALC CHIA GUSB

2.93e-03381413IPR013781
DomainIntegrin_alpha

ITGA5 ITGAV

2.98e-03111412PF00357
DomainCarboxylesterase_B_CS

NLGN3 NLGN2

4.18e-03131412IPR019819
DomainCARBOXYLESTERASE_B_2

NLGN3 NLGN2

4.85e-03141412PS00941
DomainCOesterase

NLGN3 NLGN2

4.85e-03141412PF00135
DomainLdl_recept_b

LDLR NID1

4.85e-03141412PF00058
DomainLDLRB

LDLR NID1

4.85e-03141412PS51120
DomainCarbesteraseB

NLGN3 NLGN2

4.85e-03141412IPR002018
DomainLY

LDLR NID1

5.57e-03151412SM00135
DomaincAMP_dep_PK_reg_su_I/II_a/b

PRKAR1A PRKAR1B

5.57e-03151412IPR003117
DomainLDLR_classB_rpt

LDLR NID1

5.57e-03151412IPR000033
DomaincNMP-bd_CS

PRKAR1A PRKAR1B

6.34e-03161412IPR018488
DomainIntegrin_alpha_C_CS

ITGA5 ITGAV

6.34e-03161412IPR018184
DomainGal_mutarotase_SF_dom

MAN2A2 GAA

7.15e-03171412IPR011013
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP2 RIMBP3B

1.37e-095143417855024
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MCPH1 STARD10 OBSCN AAK1 ATP8B1 JMJD1C HPS3 SH3BP4 PCNX2 PACS1 NLGN3 PTPDC1 PTPRB LATS2 PTPRS SH3PXD2A MICAL2 KLHL23 PRKAR1B MACF1 NLGN2 RAPGEF2 ANKS1A

4.57e-0814891432328611215
Pubmed

Activation of integrin α5 mediated by flow requires its translocation to membrane lipid rafts in vascular endothelial cells.

ITGA5 ITGAV LDLR

6.81e-083143326733684
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

6.81e-08314337926498
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

6.81e-08314339561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

6.81e-083143321455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

6.81e-083143319800305
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

6.81e-083143324170207
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

6.81e-08314333014868
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

6.81e-08314332799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

6.81e-083143319872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

6.81e-08314331968039
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

6.81e-08314338053437
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

6.81e-08314332566575
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

6.81e-08314332229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

6.81e-083143325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

6.81e-083143319890696
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

6.81e-08314338244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

6.81e-083143321407214
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

6.81e-08314336774973
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

6.81e-08314336300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

6.81e-083143322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

6.81e-083143324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

6.81e-08314338038355
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

6.81e-08314332227273
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

6.81e-083143323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

6.81e-083143324125879
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

6.81e-08314338751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

6.81e-08314333554488
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

6.81e-083143323521833
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

6.81e-08314333017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

6.81e-083143321989121
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

6.81e-08314339855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

6.81e-08314339797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

6.81e-08314332478370
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

6.81e-08314333815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

6.81e-083143310675278
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

6.81e-08314333780036
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

6.81e-08314332901984
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

6.81e-08314333839486
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

6.81e-08314333467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

6.81e-08314334586732
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

6.81e-08314332892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

6.81e-083143324383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

6.81e-08314331455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

6.81e-08314332831884
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

6.81e-08314332032552
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

6.81e-08314331812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

6.81e-08314337923573
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

6.81e-08314339061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

6.81e-083143312588289
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

6.81e-083143323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

6.81e-083143311566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

6.81e-08314331956484
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

6.81e-08314338540382
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

6.81e-083143322992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

6.81e-083143320981206
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

6.81e-08314338504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

6.81e-083143321970995
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

6.81e-083143320428942
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

6.81e-08314339525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

6.81e-08314337886402
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

6.81e-083143317379991
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

6.81e-083143321547904
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGA3

2.71e-074143323047493
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGA3

2.71e-074143311915945
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGA3

2.71e-07414338322031
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

2.71e-074143319091768
Pubmed

Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.

PGA4 PGA5 PGA3

2.71e-074143317136346
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGA3

2.71e-074143312698190
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGA3

6.77e-075143322066020
Pubmed

Integrins are required for the differentiation of visceral endoderm.

ITGA5 ITGAV NID1

2.35e-067143319118216
Pubmed

The structure and expression of the human neuroligin-3 gene.

NLGN3 NLGN2

1.68e-052143210767552
Pubmed

Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.

SLC22A4 SLC22A5

1.68e-052143221695374
Pubmed

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.

SLC22A4 SLC22A5

1.68e-052143216469794
Pubmed

Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system.

PRKAR1A PRKAR1B

1.68e-05214321448119
Pubmed

Gene expression of carnitine organic cation transporters 1 and 2 (OCTN) is downregulated in patients with ulcerative colitis.

SLC22A4 SLC22A5

1.68e-052143221910182
Pubmed

Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.

SLC22A4 SLC22A5

1.68e-052143218274826
Pubmed

IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells.

ITGA5 NISCH

1.68e-052143212868002
Pubmed

Distinct roles for extracellular and intracellular domains in neuroligin function at inhibitory synapses.

NLGN3 NLGN2

1.68e-052143227805570
Pubmed

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

PGA4 PGA5

1.68e-05214322714789
Pubmed

Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.

SLC22A4 SLC22A5

1.68e-052143219814996
Pubmed

Comparison of cDNA-derived protein sequences of the human fibronectin and vitronectin receptor alpha-subunits and platelet glycoprotein IIb.

ITGA5 ITGAV

1.68e-05214322450560
Pubmed

Activation of human pepsinogens.

PGA4 PGA5

1.68e-05214323197840
Pubmed

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

SLC22A4 SLC22A5

1.68e-052143221606177
Pubmed

Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.

SLC22A4 SLC22A5

1.68e-052143220020740
Pubmed

The PDZ domain of the guanine nucleotide exchange factor PDZGEF directs binding to phosphatidic acid during brush border formation.

RAPGEF6 RAPGEF2

1.68e-052143224858808
Pubmed

ITGAV and ITGA5 diversely regulate proliferation and adipogenic differentiation of human adipose derived stem cells.

ITGA5 ITGAV

1.68e-052143227363302
Pubmed

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.

SLC22A4 SLC22A5

1.68e-052143216333318
Pubmed

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.

SLC22A4 SLC22A5

1.68e-052143221793125
Pubmed

SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population.

SLC22A4 SLC22A5

1.68e-052143219659785
Pubmed

Expression and structural analysis of human neuroligin 2 and neuroligin 3 implicated in autism spectrum disorders.

NLGN3 NLGN2

1.68e-052143236479216
Pubmed

Characterization of organic cation/carnitine transporter family in human sperm.

SLC22A4 SLC22A5

1.68e-052143212788076
Pubmed

Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis.

SLC22A4 SLC22A5

1.68e-052143221706137
Pubmed

Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.

SLC22A4 SLC22A5

1.68e-052143222325173
Pubmed

Molecular and functional characterization of organic cation/carnitine transporter family in mice.

SLC22A4 SLC22A5

1.68e-052143211010964
Pubmed

Correlation of DNA Repair Gene Polymorphisms With Clinical Outcome in Patients With Locally Advanced Non-Small-Cell Lung Cancer Receiving Induction Chemotherapy Followed by Surgery.

ERCC2 RRM1

1.68e-052143227908619
Pubmed

Crystal structure of human pepsin and its complex with pepstatin.

PGA4 PGA5

1.68e-05214327663352
Pubmed

Loss of Reelin protects against atherosclerosis by reducing leukocyte-endothelial cell adhesion and lesion macrophage accumulation.

RELN LDLR

1.68e-052143226980442
Pubmed

A mutation in the ATP7B copper transporter causes reduced dopamine beta-hydroxylase and norepinephrine in mouse adrenal.

ATP7B DBH

1.68e-052143212718440
Cytoband3q13.13-q13.2

PLA1A CD96

9.63e-06214323q13.13-q13.2
GeneFamilyFibronectin type III domain containing

IL12RB1 MYOM1 OBSCN TYRO3 PTPRB PTPRS OSMR

1.11e-05160867555
GeneFamilyZinc fingers MIZ-type

PIAS2 PIAS3

4.62e-04786285
GeneFamilyATAC complex

WDR5 SGF29

1.69e-03138621058
CoexpressionAIZARANI_LIVER_C9_LSECS_1

RELN ITGA5 JMJD1C PTPRB NISCH PRKAR1A MACF1 NID1 OSMR ANKS1A

6.97e-0630414310M39113
CoexpressionGSE16266_CTRL_VS_LPS_STIM_MEF_UP

ITGA5 ITGAV DENND3 SH3BP4 TYRO3 PSME4 SLC22A4 TLR1

1.37e-051981438M7219
CoexpressionGSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP

ING3 AAK1 CLDN15 PCNX2 NISCH MACF1 TMEM41B CD96

1.42e-051991438M7596
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 CACNA2D3

2.00e-06181143709a574a3257e25c8b05a2ab20623a6b07331411a
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 CACNA2D3

2.00e-061811437ac4142aa93706b7067f63d2d38e2456859e60768
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

EXOC6 ATP8B1 ITGA5 PKHD1L1 PTPRB PLA1A OSMR

2.15e-06183143746be9f96755c7b65aeac061d95d15abeb6466034
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 ART5

2.57e-06188143790dc0e15798d0b984518ad58c7e416e30aff687a
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 ART5

2.57e-061881437f63dfd076ced81013918363282ae25cbbd8948ae
ToppCellfacs-Heart-LA/RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 ART5

2.57e-0618814370554d542149cef654ff1e5e32dfbffd8990b52bd
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 DBH TECRL BMP10 ITGB1BP2 ART5 CACNA2D3

2.67e-061891437e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Heart-LA/RA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 ART5

2.67e-061891437a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 DBH TECRL BMP10 ITGB1BP2 ART5 CACNA2D3

2.67e-061891437b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellfacs-Heart-LA/RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN TECRL BMP10 ITGB1BP2 ART5

2.67e-061891437efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN DBH TECRL FREM2 ITGB1BP2

2.96e-061921437f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 STARD10 OBSCN DBH TECRL FREM2 ITGB1BP2

2.96e-0619214371a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCellSepsis-ICU-SEP-Myeloid-cDC2|ICU-SEP / Disease, condition lineage and cell class

EXOC6 SWT1 INTS7 SH3BP4 PTPDC1 SH3PXD2A ANKDD1A

3.87e-06200143709d5c3a3d2b42b15c769dc2bc14b6c0d5cc38f91
ToppCellfacs-Heart-LA-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD10 OBSCN DBH TRIM10 ITGB1BP2 CACNA2D3

1.57e-05165143695866f7cc6eb1bb51a034a104a0eb2a53b0256f2
ToppCellfacs-Heart-LA-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STARD10 OBSCN DBH TRIM10 ITGB1BP2 CACNA2D3

1.57e-051651436f8bfe336b9a4460b9349c01acd0bd3167812662f
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 OBSCN DBH TECRL ITGB1BP2 ART5

1.98e-051721436ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCellfacs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYOM1 OBSCN DBH TECRL ITGB1BP2 ART5

1.98e-051721436bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCRL2 AASDH DMXL1 RFTN1 PIAS3 FARS2

2.33e-05177143695760841b3f085d38c4926b258a33563d93a2016
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLDN15 SLC9A3 PTPRB MICAL2 OSMR CRISPLD1

2.56e-05180143667c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN15 RFTN1 PTPRB MICAL2 OSMR CRISPLD1

2.64e-0518114364ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLDN15 SLC9A3 PTPRB MICAL2 OSMR CRISPLD1

2.72e-051821436ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLDN15 SLC9A3 PTPRB MICAL2 OSMR CRISPLD1

2.72e-05182143647ff6b4002a4167412c79210651316d1342503f9
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RELN IQGAP2 PKHD1L1 TRIM10 MICAL2 SLC22A4

3.08e-051861436294839944266407c40ef86e1d3e0fce4652b70ff
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

EXOC6 ATP8B1 PKHD1L1 PTPRB KIAA1549L PLA1A

3.17e-0518714362d20193a6cacdfa4877457c97b0077408942186c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PKHD1L1 MICAL2 ANKDD1A NID1 KIF17

3.17e-05187143665d406122dffe18279f14a1ed35ba091730b97be
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PKHD1L1 MICAL2 ANKDD1A NID1 KIF17

3.17e-0518714364c15c0ed41a55271fc793cb76fee97fa64190369
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RELN PKHD1L1 MICAL2 ANKDD1A NID1 KIF17

3.17e-0518714365274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN IQGAP2 PKHD1L1 TRIM10 MICAL2 SLC22A4

3.27e-0518814365d6faf45a9c0794b0c30b0a0601c10afbb8aa9ed
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN IQGAP2 PKHD1L1 TRIM10 MICAL2 SLC22A4

3.27e-051881436a0873783f0a2cd852563c05a275dddc72905ced2
ToppCellCF-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

IQGAP2 TBC1D2B AAK1 LDLR PCNX2 CD96

3.27e-05188143615057036b46c9df621ec4955aa94ca3036245d45
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RELN IQGAP2 PKHD1L1 TRIM10 MICAL2 SLC22A4

3.27e-05188143629d804232d974a8c0029300345b287005b09bade
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN OLFM4 ITGAV LDLR SH3PXD2A NISCH

3.27e-051881436a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

EXOC6 ATP8B1 ITGA5 PKHD1L1 PTPRB PLA1A

3.46e-0519014361caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP7B RAET1E CLDN15 PKHD1L1 SH3BP4 TSPO

3.57e-0519114365343a527de6b0f852f45020a91f5b4869e78f13a
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP7B RAET1E CLDN15 PKHD1L1 SH3BP4 TSPO

3.57e-051911436a25a5f9a380031fdaf57677a079f97a90f0550c0
ToppCellCTRL-Lymphoid-T_cell_&_NK_cell|Lymphoid / Disease state, Lineage and Cell class

IQGAP2 TBC1D2B AAK1 PCNX2 MICAL2 CD96

3.57e-05191143632381d353e40bce77a5b63c7bdbe360d27327d86
ToppCell15-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

RELN ITGA5 PTPRB PLA1A NID1 ART5

3.78e-0519314366ea0444fc3dc156997129387184e6418947f4b12
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

EXOC6 ATP8B1 PKHD1L1 PTPRB PLA1A OSMR

3.78e-0519314369ba688b35a9ead5d04691b3f3f15484f02dbbd0d
ToppCell15-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

RELN ITGA5 PTPRB PLA1A NID1 ART5

3.78e-051931436b1ebf8df2d55e2938e5a495ea68b80c4ac216dc0
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

RELN MAN2A2 CLDN15 TRIM10 STK11 MICAL2

3.78e-051931436be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCellSepsis-Int-URO-Lymphocyte-B-Plasmablast|Int-URO / Disease, condition lineage and cell class

FCRL2 INTS7 NLRX1 PKHD1L1 SH3BP4 PRKAR1B

4.12e-051961436e65b47d0ce1a5dd05f5f50e1639c8ec76fb42dc8
ToppCellBronchial-NucSeq-Stromal-Schwann-Schwann_Myelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RELN NUP210L KIAA1549L PIAS3 A2ML1 NLGN2

4.12e-051961436efeb272bc9e37e60d15d056b7574991c5c7501bc
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

COLGALT1 ITGA5 LDLR JMJD1C PSME4 TSPO

4.24e-051971436df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega|Control_saline / Treatment groups by lineage, cell group, cell type

PGA4 PKHD1L1 TRIM10 PSME4 MICAL2 SLC22A4

4.36e-0519814361a39a98beef68e1e6d3adc25270a3336fcc5baf4
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|Control_saline / Treatment groups by lineage, cell group, cell type

PGA4 PKHD1L1 TRIM10 PSME4 MICAL2 SLC22A4

4.36e-051981436dd80fd9671ee863aebcf4c1023d3e004cc2ee709
ToppCellControl_saline-Hematopoietic_Erythro-Megakary|Control_saline / Treatment groups by lineage, cell group, cell type

PGA4 PKHD1L1 TRIM10 PSME4 MICAL2 SLC22A4

4.36e-051981436cfc2a860bae883299987d3e374d0476ca20e1bdd
DiseaseDown syndrome (is_marker_for)

RELN ERCC2 BRIP1

1.29e-04221333DOID:14250 (is_marker_for)
Diseasedigestive system infectious disorder

TYRO3 STKLD1 CD96

2.16e-04261333MONDO_0043424
Diseasehearing loss

EXOC6 IQGAP2 LMO7DN ILDR1

2.43e-04671334EFO_0004238
DiseaseCoxsackievirus Infections

SLC22A4 SLC22A5

2.99e-0461332C0010246
DiseaseMyocarditis

SLC22A4 SLC22A5

2.99e-0461332C0027059
DiseaseCarditis

SLC22A4 SLC22A5

2.99e-0461332C0869523
Diseaseinterleukin 10 measurement

RAPGEF6 NXPE4 JMJD1C H4C7

4.35e-04781334EFO_0004750
Diseasemelanoma (implicated_via_orthology)

GALC ING3

5.55e-0481332DOID:1909 (implicated_via_orthology)
Diseaseacetylcarnitine measurement

SLC22A4 SLC22A5

5.55e-0481332EFO_0021038
Diseasebutyrylcarnitine measurement

SLC22A4 SLC22A5

5.55e-0481332EFO_0020010
Diseasetriglycerides:total lipids ratio, low density lipoprotein cholesterol measurement

LDLR JMJD1C SLC22A4 SLC22A5 MACF1

6.05e-041501335EFO_0004611, EFO_0020947
Diseasesmoking cessation

CACNA1E ZSWIM8 DBH JMJD1C SH3PXD2A NLGN2 ANKS1A

7.02e-043251337EFO_0004319
Diseasenervonoylcarnitine (C24:1) measurement

SLC22A4 SLC22A5

7.11e-0491332EFO_0800549
Diseaseunipolar depression, age at onset

FARS2 SH3PXD2A A2ML1

7.83e-04401333EFO_0003761, EFO_0004847
Diseaselignoceroylcarnitine (C24) measurement

SLC22A4 SLC22A5

1.08e-03111332EFO_0800541
Diseaseresponse to virus

MCPH1 FREM2

1.08e-03111332GO_0009615
Diseasetryptophan betaine measurement

SLC22A4 SLC22A5

1.29e-03121332EFO_0021017
Diseasehexanoylcarnitine measurement

SLC22A4 SLC22A5

1.29e-03121332EFO_0021040
DiseaseX-12707 measurement

DBH SGF29

1.29e-03121332EFO_0800720
DiseaseColorectal Carcinoma

ERCC2 ATP7B AMDHD2 OBSCN SLC44A4 HPS3 STK11 PTPRS NID1 WDR49

1.34e-0370213310C0009402
Diseasehepatocellular carcinoma (implicated_via_orthology)

ATP7B ING3 IQGAP2

1.42e-03491333DOID:684 (implicated_via_orthology)
Diseasetriglycerides to total lipids in medium LDL percentage

LDLR JMJD1C SLC22A5

1.50e-03501333EFO_0022334
Diseasehematologic cancer (implicated_via_orthology)

PIAS2 PIAS3

1.52e-03131332DOID:2531 (implicated_via_orthology)
Diseasehomostachydrine measurement

SLC22A4 SLC22A5

1.52e-03131332EFO_0021164
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLC22A4 SLC22A5

1.52e-03131332EFO_0800547
Diseasecerotoylcarnitine (C26) measurement

SLC22A4 SLC22A5

1.52e-03131332EFO_0800542
Diseasecortical thickness

RELN B4GALNT1 MCPH1 NUP210L VIT JMJD1C DENND3 SH3PXD2A MACF1 OSMR SGF29 CACNA2D3 ANKS1A

1.60e-03111313313EFO_0004840
Diseasetriglycerides to total lipids in very large VLDL percentage

LDLR JMJD1C CEACAM19

1.78e-03531333EFO_0022340
Diseasecholesteryl esters to total lipids in very large VLDL percentage

LDLR JMJD1C CEACAM19

1.78e-03531333EFO_0022258
Diseasecholesterol to total lipids in very large VLDL percentage

LDLR JMJD1C CEACAM19

1.88e-03541333EFO_0022244
Disease3-hydroxyanthranilic acid measurement

PCNX2 CREG2

2.04e-03151332EFO_0010447
Diseaseimmature platelet measurement

MYO1G IQGAP2 JMJD1C ANKDD1A

2.10e-031191334EFO_0803541
DiseaseHypertrophic Cardiomyopathy

MYOM1 OBSCN GAA

2.19e-03571333C0007194
Diseasecholesterol:total lipids ratio, intermediate density lipoprotein measurement

LDLR JMJD1C SLC22A4 MACF1

2.23e-031211334EFO_0008595, EFO_0020943
Diseaseretinal vasculature measurement

EXOC6 MBOAT1 AAK1 ITGA5 DENND3 SH3PXD2A RIMBP2 OSMR

2.44e-035171338EFO_0010554
Diseasetotal lipids in VLDL measurement

EXOC6 LDLR JMJD1C

2.54e-03601333EFO_0022314
Diseasecholesterol to total lipids in IDL percentage

LDLR JMJD1C MACF1

2.54e-03601333EFO_0022233
Diseasetriglycerides:total lipids ratio, intermediate density lipoprotein measurement

LDLR JMJD1C SLC22A4 MACF1

2.66e-031271334EFO_0008595, EFO_0020947
Diseasedocosahexaenoic acid measurement

MCPH1 LDLR JMJD1C SLC22A4

2.66e-031271334EFO_0007761
Diseasefree cholesterol in very large VLDL measurement

EXOC6 LDLR JMJD1C

2.66e-03611333EFO_0022274
Diseasereticulocyte count

MYO1G IQGAP2 JMJD1C DENND3 TRIM10 MICAL2 NISCH SLC22A4 SLC22A5 PRKAR1A OSMR GAA

2.77e-03104513312EFO_0007986
Diseasefree cholesterol in very large HDL measurement

LDLR CEACAM19 PRKAR1A

2.79e-03621333EFO_0022273
Diseasecholesterol in large VLDL measurement

EXOC6 LDLR JMJD1C

3.19e-03651333EFO_0021902
DiseaseHydrops Fetalis

SLC17A5 GUSB

3.28e-03191332C0020305
Diseaseoleoylcarnitine measurement

SLC22A4 SLC22A5

3.28e-03191332EFO_0021043
Diseaseresponse to methotrexate, neurotoxicity

MBOAT1 MACF1

3.28e-03191332EFO_0011057, GO_0031427
Diseasebreast carcinoma (is_marker_for)

BRIP1 ATP7B STK11

3.33e-03661333DOID:3459 (is_marker_for)
Diseaseschizophrenia (implicated_via_orthology)

RELN MAN2A2 NLGN2

3.62e-03681333DOID:5419 (implicated_via_orthology)
Diseasefree cholesterol in large VLDL measurement

EXOC6 LDLR JMJD1C

3.62e-03681333EFO_0022265
Diseasephospholipids:total lipids ratio

LDLR JMJD1C CEACAM19 PRKAR1A MACF1

3.74e-032271335EFO_0020946
Diseasemitochondrial DNA measurement

TBRG4 RRM1 LDLR JMJD1C STK11 PTPRS

3.80e-033281336EFO_0006312
Diseaselung cancer

BRIP1 ATP8B1

4.00e-03211332MONDO_0008903
Diseasedocosahexaenoic acid to total fatty acids percentage

JMJD1C SLC22A4

4.00e-03211332EFO_0022262
Diseasemetabolite measurement, diet measurement

SLC44A4 LDLR JMJD1C

4.09e-03711333EFO_0004725, EFO_0008111
Diseaseperceived unattractiveness to mosquitos measurement

RAPGEF6 SLC44A4 NID1

4.26e-03721333EFO_0008380
Diseaseotitis media (implicated_via_orthology)

FBXO11 NISCH

4.39e-03221332DOID:10754 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
WTANTLDAVVVGVDY

AADACL2

131

Q6P093
TNVTNITWYVNDVPT

CEACAM18

161

A8MTB9
WTTVLYNTNDALGAT

CACNA1E

311

Q15878
YIDSSINNVSSGDVW

AAK1

106

Q2M2I8
YQVNLTASLGTWDVA

B4GALNT1

176

Q00973
ATPWDQVSYVSQVSL

ATP7B

1416

P35670
TSTQEVVQYNWETGD

GSG1

71

Q2KHT4
DQQAIISGESIYWSQ

A2ML1

1161

A8K2U0
ITTIEWNDVTLYQAF

CHIA

66

Q9BZP6
FNVYGITEVSSWATI

AASDH

341

Q4L235
VGEWLESIGLQQYES

ANKS1A

701

Q92625
QNQVWVGSEDSVIYI

DENND3

956

A2RUS2
ELDVSGILATQVYTW

DMXL1

2666

Q9Y485
GILATQVYTWVDDDI

DMXL1

2671

Q9Y485
GYVIVSSVSWAVTNE

CREG2

31

Q8IUH2
NGLVATEVSTWFYVR

ATP5MGL

76

Q7Z4Y8
VITVNFQIGLDTSYW

ATP8B1

1081

O43520
VYATSTWGELTQTLG

RAET1E

81

Q8TD07
ISRIETSNVIWVGNY

OSMR

71

Q99650
TIQGYDAIVVEQWTV

RFTN1

366

Q14699
LQNVTATSANITWVY

RIMBP3B

1001

A6NNM3
LQNVTATSANITWVY

RIMBP3C

1001

A6NJZ7
QLESVSNGWTVYRIA

INTS7

516

Q9NVH2
VTVEGYWQITVDSIT

PGA5

246

P0DJD9
GVQIQESTSWNEYTF

PTPRB

156

P23467
VFLENVIWYAVTNTE

H4C7

61

Q99525
LKDVVAYVEVWSSNG

MCPH1

6

Q8NEM0
DWHQTDSLVVVTVYG

ITGB1BP2

221

Q9UKP3
NVDLYELGSTSVQQW

LATS2

356

Q9NRM7
VVGTTALYLVEEAWA

LMO7DN

101

F2Z398
VYRQDSATQWFTGII

JMJD1C

196

Q15652
ESAGYVEVQVWRTGT

FREM2

2021

Q5SZK8
VVPESDSNSQVDWTY

ING3

341

Q9NXR8
TWEITQTQYILEGYS

PCNX2

1496

A6NKB5
SAVVVTWESVAPYQG

NID1

151

P14543
DYTTSAQLQDVVVTW

ILDR1

46

Q86SU0
EVVQVRWTDGQVYGA

KDM4A

961

O75164
ESTVASWYEQGILEN

ERCC2

546

P18074
ESLAVAQNTYAVSWF

MFSD1

151

Q9H3U5
RDYWVITVLQGVDNS

KIAA1549L

1056

Q6ZVL6
QAIKGVYSSWVTDNI

PTPDC1

76

A2A3K4
GTSYQQWLSSVETLL

HAUS5

221

O94927
VVVSLTEGTAVSEYW

NLRX1

896

Q86UT6
VVAVDADSGYNAWLS

PCDHGB3

591

Q9Y5G1
VTQGLVTRAYTDELW

EXOC6

351

Q8TAG9
AVWVAVETSAYQVEL

MAB21L3

171

Q8N8X9
TVEAYSAAVQSQLQW

MACF1

756

Q9UPN3
TTDWQGQYVAELLQD

PACS1

571

Q6VY07
VTVEGYWQITVDSIT

PGA3

246

P0DJD8
IQANYTVGADSWAID

RELN

1746

P78509
SEYEIWVSAVNSIGQ

PTPRS

396

Q13332
AIQQTYSWTNQIDIS

BRIP1

551

Q9BX63
QITAQAWDGTTDYQV

HTATSF1

341

O43719
EVAQAQTEVTWYKDG

OBSCN

1281

Q5VST9
QVATAVQWTKAEGSY

ITGA5

981

P08648
IIQSGSALSSWAVNY

NLGN3

311

Q9NZ94
VQSYNSDINEWSLIT

KLHL23

436

Q8NBE8
LVSGEIYGTNSEWET

BMP10

186

O95393
YSRVLGVSDVITWND

DTX3L

691

Q8TDB6
VNGVYWSESLNKVFV

CACNA2D3

186

Q8IZS8
EVYSNTLAGVWVTTG

FBXO11

611

Q86XK2
DLSINDTSVTVIWYG

FBXO15

216

Q8NCQ5
THYTQVVWATSNRIG

CRISPLD1

166

Q9H336
VDAWASVTEELGAQY

GALT

151

P07902
AHSYAIVWVNGVDTL

GUSB

126

P08236
SFYWQGQLISDQVAE

ITGAV

206

P06756
EGSLELSWNVSYTQE

DBH

56

P09172
DSGTYQVAITINSEW

CEACAM19

116

Q7Z692
NSYWRVSTVHGNVIT

CLDN15

26

P56746
WGYSSTAITRQVVEN

GAA

376

P10253
DQAGVSVLYTVTLWV

IL12RB1

101

P42701
VYDAGTWAVTQLAVS

MBOAT1

421

Q6ZNC8
WSSATEAVPDVYQVS

MAN2A2

691

P49641
ETDVYVNNEWATSVG

PRKAR1A

181

P10644
EVDVYVNGEWVTNIS

PRKAR1B

181

P31321
GQQSDYAVSEPVWIT

KIAA1210

1566

Q9ULL0
YETQSAADWTVQIVV

LAMB4

626

A4D0S4
TTNLSAYQSVQETWL

SLC44A4

296

Q53GD3
ELQISAVWSEDTGSY

FCRL2

161

Q96LA5
GYVSDTETSVVWNNE

COLGALT1

566

Q8NBJ5
SNTISIIGDYNWTNL

GALC

546

P54803
NTVGEWQTVFYIAAA

SLC17A5

451

Q9NRA2
GWEFSQDVYLSTVVT

SLC22A4

116

Q9H015
GWEFSQDVYLSTIVT

SLC22A5

116

O76082
VWFTDNLEAAATYVQ

NLGN2

121

Q8NFZ4
SLEVATQYGWVLDAE

TBRG4

511

Q969Z0
EGYQHVNVTDLTTSW

MICAL2

531

O94851
QALSVADTSVYGWAT

NUP210L

1661

Q5VU65
VQGEWNSVLEFTYSN

OSBPL11

631

Q9BXB4
VTVEGYWQITVDSIT

PGA4

246

P0DJD7
QISISWASEIGKNYS

PIAS2

276

O75928
DSGDWVLLNVYDSIQ

KIF17

791

Q9P2E2
TVSTYVIRDEWGNQI

TAF3

851

Q5VWG9
WGTVSSYNVLVDKET

RIMBP2

326

O15034
DSWYVILNGTVEISH

RAPGEF6

316

Q8TEU7
TYSRAGVSVWVQAVE

STARD10

46

Q9Y365
TWSHQIGDSYRDVIQ

SH3BP4

901

Q9P0V3
VAEAGWNLYIVNTIS

HPS3

481

Q969F9
IDAWDITIAYGTNNV

NXPE4

511

Q6UWF7
LQNVTATSANITWVY

RIMBP3

1001

Q9UFD9
EVTVGYIRENIWSAS

IQGAP2

646

Q13576
YAVVGTVWNAATTGL

SLC9A3

146

P48764
VDIWSAGVTLYNITT

STK11

236

Q15831
SVWITIYQNSTDVFQ

SWT1

761

Q5T5J6
TDVASAWTENYGLQE

STXBP4

191

Q6ZWJ1
AVDENGLWVIYSTEA

OLFM4

386

Q6UX06
NISQNYISELWTSDI

TLR1

51

Q15399
HVDAIEQQWTGTRSY

ANKDD1A

441

Q495B1
NTIVVNWSSEFGRNY

PIAS3

256

Q9Y6X2
ATNANVIAVDWIYGS

PLA1A

111

Q53H76
DSWSVILNGSVEVTY

RAPGEF2

171

Q9Y4G8
GVWEKTVNTEENVYA

CD96

21

P40200
AQQLWYAIIESQTET

RRM1

386

P23921
SVYQELFITWNGEIS

STKLD1

86

Q8NE28
YGNSVLVSIVNVVWT

TAS2R9

76

Q9NYW1
GDEQWILAEVVSYSH

SGF29

171

Q96ES7
YIINVTWSDSTSQTI

SH3PXD2A

26

Q5TCZ1
TEVTQAIWDGYLQQA

TBC1D23

211

Q9NUY8
SYDGEIVLWNNSTEN

WDR49

301

Q8IV35
TVYIIQVTDGSHEWT

NISCH

31

Q9Y2I1
VAVYFTQNEWASLDS

ZNF620

16

Q6ZNG0
VITYAIGVAWAAQEE

VIT

621

Q6UXI7
SELTVVNNGTVAIWY

MYCBPAP

446

Q8TBZ2
WQEGEEIVITTTSYD

PKHD1L1

3191

Q86WI1
VLGEVYLHTWITENT

GTF3C4

691

Q9UKN8
TALSNITVETYNDWG

PSME4

1411

Q14997
QEYWNITDLVAISTF

TRPM1

896

Q7Z4N2
ILTDQCLTYEQITGW

ZSWIM8

371

A7E2V4
DYEVGWVTFTNAVTR

TRIM10

436

Q9UDY6
TLYATDLGQQVSWTT

TECRL

131

Q5HYJ1
LYQLTTAGEAVSWNS

TMEM41B

251

Q5BJD5
NLVASGANESEIYIW

SEC31A

136

O94979
SVYDNLSPVVTTWQN

FARS2

111

O95363
ADVVSTTENVAVYIW

PTS

101

Q03393
TENQEVSTGVKWENY

TBC1D2B

626

Q9UPU7
SGSEDNLVYIWNLQT

WDR5

276

P61964
DNLYTVQSDVWAFGV

TYRO3

706

Q06418
QISEETWNFLQSIYG

USP33

896

Q8TEY7
SGAAAATTVAWYQVS

TSPO

116

P30536
SNIYWTDSVLGTVSV

LDLR

486

P01130
TWQSVEYFNNATIVD

MYO1G

441

B0I1T2
SQDGAQSLVTLWSYN

ART5

236

Q96L15
VQATYISGELVWQAD

AMDHD2

391

Q9Y303
VEYLSWEVTGECNVL

MYOM1

1361

P52179