Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnegative regulation of microtubule depolymerization

MAP1A APC2 CAMSAP3 TTBK2 ARHGEF2

4.06e-06381315GO:0007026
GeneOntologyBiologicalProcessregulation of microtubule depolymerization

MAP1A APC2 CAMSAP3 TTBK2 ARHGEF2

6.74e-06421315GO:0031114
GeneOntologyBiologicalProcessnegative regulation of microtubule polymerization or depolymerization

MAP1A APC2 CAMSAP3 TTBK2 ARHGEF2

1.78e-05511315GO:0031111
GeneOntologyBiologicalProcessmicrotubule depolymerization

MAP1A APC2 CAMSAP3 TTBK2 ARHGEF2

6.27e-05661315GO:0007019
GeneOntologyCellularComponentzonula adherens

CAMSAP3 SORBS1 KIFC3

1.47e-0581363GO:0005915
GeneOntologyCellularComponentapical junction complex

CAMSAP3 NFASC SORBS1 FRMD4B AMOTL1 KIFC3 ARHGEF2

7.97e-051581367GO:0043296
GeneOntologyCellularComponentcell-cell junction

JCAD SIPA1L3 CAMSAP3 OBSCN NFASC SORBS1 FRMD4B HEPACAM AMOTL1 KIRREL1 KIFC3 ARHGEF2 ARHGEF6

1.30e-0459113613GO:0005911
GeneOntologyCellularComponentcell leading edge

JCAD ABI1 APC2 SRCIN1 FRMD4B AMOTL1 MACF1 GNAS ARHGEF2 ARHGAP45 ARHGEF6

4.35e-0450013611GO:0031252
GeneOntologyCellularComponentanchoring junction

JCAD SIPA1L3 CAMSAP3 OBSCN NFASC SORBS1 SRCIN1 FRMD4B HEPACAM AFAP1 AMOTL1 SORBS3 KIRREL1 KIFC3 ARHGEF2 ARHGEF6

6.16e-0497613616GO:0070161
DomainIg_I-set

OBSCN FSTL4 NFASC HEPACAM KIRREL1 SIGLEC11 SIGLEC1 ROBO3

7.68e-051901368IPR013098
DomainI-set

OBSCN FSTL4 NFASC HEPACAM KIRREL1 SIGLEC11 SIGLEC1 ROBO3

7.68e-051901368PF07679
DomainSOHO

SORBS1 SORBS3

1.57e-0431362PS50831
DomainSorb

SORBS1 SORBS3

1.57e-0431362SM00459
DomainSorb

SORBS1 SORBS3

1.57e-0431362PF02208
DomainSoHo_dom

SORBS1 SORBS3

1.57e-0431362IPR003127
DomainSH3

DOCK4 ABI1 OBSCN SORBS1 PRAM1 SORBS3 MACF1 ARHGEF6

1.86e-042161368PS50002
DomainSH3_domain

DOCK4 ABI1 OBSCN SORBS1 PRAM1 SORBS3 MACF1 ARHGEF6

2.11e-042201368IPR001452
DomainIGc2

OBSCN FSTL4 NFASC HEPACAM KIRREL1 SIGLEC11 SIGLEC1 ROBO3

3.30e-042351368SM00408
DomainIg_sub2

OBSCN FSTL4 NFASC HEPACAM KIRREL1 SIGLEC11 SIGLEC1 ROBO3

3.30e-042351368IPR003598
DomainNIDO_dom

NID2 MUC4

5.19e-0451362IPR003886
DomainFYrich_C

KMT2B KMT2C

5.19e-0451362IPR003889
DomainFYrich_N

KMT2B KMT2C

5.19e-0451362IPR003888
DomainFYRC

KMT2B KMT2C

5.19e-0451362SM00542
DomainFYRN

KMT2B KMT2C

5.19e-0451362SM00541
DomainNIDO

NID2 MUC4

5.19e-0451362SM00539
DomainNIDO

NID2 MUC4

5.19e-0451362PF06119
DomainNIDO

NID2 MUC4

5.19e-0451362PS51220
DomainFYRN

KMT2B KMT2C

5.19e-0451362PF05964
DomainFYRC

KMT2B KMT2C

5.19e-0451362PF05965
DomainFYRC

KMT2B KMT2C

5.19e-0451362PS51543
DomainFYRN

KMT2B KMT2C

5.19e-0451362PS51542
DomainEPHD

KMT2B KMT2C RAI1

5.26e-04221363PS51805
DomainSH3

DOCK4 ABI1 OBSCN SORBS1 PRAM1 SORBS3 ARHGEF6

1.04e-032161367SM00326
DomainKA1/Ssp2_C

MARK3 PRKAA2

1.08e-0371362IPR028375
DomainC1

DGKH KMT2C ARHGEF2 ARHGAP45

1.29e-03651364SM00109
DomainPE/DAG-bd

DGKH KMT2C ARHGEF2 ARHGAP45

1.37e-03661364IPR002219
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC16 MUC5B MUC12 MUC4

3.45e-0616964M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC16 MUC5B MUC12 MUC4

4.49e-0617964M27412
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC16 MUC5B MUC12 ADAMTS10 ADAMTS9 MUC4

6.63e-0668966M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B MUC12 B3GNT3 ADAMTS10 ADAMTS9 MUC4

1.04e-05111967M27416
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC12 MUC4

1.62e-0523964M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC16 MUC5B MUC12 MUC4

2.69e-0526964M27483
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC16 MUC5B MUC12 B3GNT3 MUC4

6.28e-0562965M546
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC16 MUC5B B3GNT3 ADAMTS10 ADAMTS9 MUC4

9.81e-05109966MM15164
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC16 MUC5B MUC4

3.72e-0421963MM15706
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

MUC16 MUC5B MUC12 ADAMTS10 ADAMTS9 MUC4

4.30e-04143966M27275
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PABIR1 DOCK4 JCAD ABI1 MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SIK1 SORBS1 CCDC6 CDK14 GLCCI1 USP31 TBC1D4 PRKAA2 RNF10 MIEF1 RAB11FIP5 MACF1 GNAS ARHGEF2 SRRM2 USP6NL

8.36e-158611392536931259
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EP400 LARP1 NFASC SRCIN1 POGZ CDK14 FRMD4B KMT2C AFAP1 NUP155 NBEAL2 RNF10 AUTS2 RAB11FIP5 USP6NL RAI1 IQCE

4.80e-115291391714621295
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

FOXK2 MARK3 SIPA1L3 SHB CAMSAP3 OBSCN LARP1 NFASC DGKH SRCIN1 CDK14 INKA2 BPTF KMT2C CFAP20DC TBC1D4 TESMIN EEPD1 PRKAA2 AUTS2 MACF1 CACNA1H GNAS CAMTA1 RAI1

1.12e-0914891392528611215
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DOCK4 EP400 MARK3 SORBS1 POGZ USP19 USP31 TCF25 MACF1 DISP2 CACNA1H ARRDC3 CAMTA1 SRRM2

1.13e-094071391412693553
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

CACNA1A ABI1 MAP1A CAMSAP3 SORBS1 SRCIN1 GLCCI1 RIN1 RAB11FIP5 MACF1 ARHGEF2 SRRM2

1.73e-083471391217114649
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 FOXK2 KMT2B EP400 SIPA1L3 OBSCN FRMD8 ZFPM1 ECE1 ZDHHC8 KMT2C NBEAL2 SORBS3 DISP2 CACNA1H KIFC3 ARHGEF2 LTBP4 RAI1 IQCE

1.84e-0811051392035748872
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

JCAD FOXK2 GATAD2A EP400 LARP1 POGZ RBM20 KMT2C JAZF1 AUTS2 NCOA1 BICRAL

7.72e-083981391235016035
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KMT2B EP400 CAMSAP3 LARP1 POGZ ZFPM1 CCDC6 USP19 BPTF TBC1D4 LMNA SORBS3 ARHGEF2 SRRM2 MN1 ARHGEF6

9.25e-087741391615302935
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FOXK2 GATAD2A CAMSAP3 LARP1 CCDC6 GLCCI1 RIN1 TBC1D4 LMNA SORBS3 ARHGEF2 SRRM2 ARHGEF6

1.29e-075031391316964243
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MRPS31 KMT2B CAMSAP3 OBSCN LARP1 NFASC DGKH STOX1 KMT2C TBC1D4 LMNA ADAMTS9 TNR RAI1 IQCE

2.87e-077361391529676528
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC16 MUC5B MUC12 MUC4

7.16e-0718139418834073
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

DOCK4 MARK3 LARP1 TBC1D4 MIEF1 RAB11FIP5 ARHGEF2 SRRM2 ARHGEF6

9.51e-07255139915324660
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

CCDC6 NFATC2 RAB11FIP5 KIRREL1 SRRM2 USP6NL ARHGEF6

1.14e-06133139715144186
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

MARK3 APC2 CAMSAP3 LARP1 NFASC SORBS1 STOX1 DLGAP3 AMOTL1 MACF1 TNR

1.38e-064301391132581705
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

NID2 ZSWIM8 GATAD2A EP400 MAP1A ABCA12 POGZ BPTF TCF25 JAZF1 RAB11FIP5 MACF1 BICRAL SIGLEC1 SRRM2 LTBP4 RAI1

2.49e-0611161391731753913
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZSWIM8 CDK14 USP19 TTBK2 RAB11FIP5 CAMTA1

3.20e-06100139610048485
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

FOXK2 GATAD2A EP400 MAP1A CCDC6 BPTF RIN1 AFAP1 RAB11FIP5 MACF1 SRRM2

3.37e-064721391138943005
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

DOCK4 ZSWIM8 EP400 MAP1A SORBS1 CCDC6 PAF1 RBM20 TBC1D4 RAB11FIP5 MACF1 GNAS

4.64e-065881391238580884
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

VWA5B2 CACNA1A ZFPM1 KMT2C TESMIN NCOA1 SRRM2 IQCE

4.77e-06233139837704626
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PABIR1 JCAD SIPA1L3 CAMSAP3 EYA1 CCDC6 PAF1 RBM20 USP31 TBC1D4 NUP155 SORBS3 RAB11FIP5 KIRREL1 ARHGEF2 SRRM2

4.94e-0610491391627880917
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

CAMSAP3 SORBS1 SRCIN1 DLGAP3 AFAP1

7.51e-0667139529254152
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

ABI1 MARK3 SHB USP31 NUP155 EEPD1 RAB11FIP5 KIRREL1 MACF1 USP6NL

8.08e-064211391036976175
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

JCAD EP400 MAP1A APC2 TEX14 NUP155 LMNA ARRDC3 CAMTA1 IQCE

9.71e-064301391035044719
Pubmed

Interaction network of human early embryonic transcription factors.

FOXK2 KMT2B EP400 POGZ BPTF KMT2C AUTS2 NCOA1 RAI1

1.27e-05351139938297188
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

JCAD MARK3 SIPA1L3 LARP1 SORBS1 CCDC6 TBC1D4 AMOTL1 KIRREL1 ARHGEF2

1.33e-054461391024255178
Pubmed

Glycosylation of a CNS-specific extracellular matrix glycoprotein, tenascin-R, is dominated by O-linked sialylated glycans and "brain-type" neutral N-glycans.

SIGLEC1 TNR

1.59e-052139210406848
Pubmed

Vinexin family (SORBS) proteins regulate mechanotransduction in mesenchymal stem cells.

SORBS1 SORBS3

1.59e-052139230068914
Pubmed

Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.

MUC16 MUC4

1.59e-052139223544943
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

1.59e-052139214690056
Pubmed

The CAMSAP3-ACF7 Complex Couples Noncentrosomal Microtubules with Actin Filaments to Coordinate Their Dynamics.

CAMSAP3 MACF1

1.59e-052139227693509
Pubmed

Non-centrosomal microtubules regulate F-actin organization through the suppression of GEF-H1 activity.

CAMSAP3 ARHGEF2

1.59e-052139223432781
Pubmed

Dissection of complex molecular interactions of neurofascin with axonin-1, F11, and tenascin-R, which promote attachment and neurite formation of tectal cells.

NFASC TNR

1.59e-05213929722619
Pubmed

Control of apico-basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7.

CAMSAP3 MACF1

1.59e-052139227802168
Pubmed

Clinical and mutational spectrum in a cohort of 105 unrelated patients with dilated cardiomyopathy.

RBM20 LMNA

1.59e-052139221846512
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

CACNA1A ABI1 MAP1A MARK3 SIPA1L3 CAMSAP3 LARP1 NFASC SORBS1 SRCIN1 USP31 RIN1 DLGAP3 AFAP1 LMNA MACF1 ARHGEF2 TNR

1.70e-0514311391837142655
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

MAP1A CAMSAP3 SORBS1 SRCIN1 DLGAP3 MACF1 GNAS TNR

1.86e-05281139828706196
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZSWIM8 KMT2B TTLL5 BICRAL ARHGEF2

2.69e-0587139512465718
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

KMT2B GATAD2A EP400 POGZ BPTF KMT2C

2.80e-05146139623892456
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

FOXK2 KMT2B GATAD2A POGZ BPTF KMT2C BEND7 AUTS2 ARHGEF2 ARHGEF6

3.23e-054951391027705803
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ABI1 SHB OBSCN SORBS1 PAF1 TBC1D4 LMNA ADAMTS9 RNF10 MACF1

3.34e-054971391023414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

EXPH5 CAMSAP3 OBSCN SORBS1 SRCIN1 KMT2C MIDN NBEAL2 MUC4 RAI1

3.34e-054971391036774506
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CACNA1A ABI1 SIPA1L3 APC2 CAMSAP3 NFASC SORBS1 CCDC6 PAF1 DLGAP3 MACF1 ARHGEF2 TNR RAI1

3.38e-059631391428671696
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SIPA1L3 NFASC KMT2C RNF10 AUTS2 MACF1 CAMTA1

3.58e-05225139712168954
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

FOXK2 KMT2B GATAD2A EP400 LARP1 POGZ PAF1 BPTF PRAM1 KMT2C NCOA1 BICRAL ARHGEF2 SRRM2 RAI1

3.75e-0511031391534189442
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MAP1A SORBS1 SRCIN1 ZDHHC8 LMNA MACF1 SRRM2

4.23e-05231139716452087
Pubmed

Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.

MUC16 MUC4

4.75e-053139223053434
Pubmed

Association study between polymorphisms in the CACNA1A, CACNA1C, and CACNA1H genes and drug-resistant epilepsy in the Chinese Han population.

CACNA1A CACNA1H

4.75e-053139226216687
Pubmed

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.

MUC16 MUC4

4.75e-053139230236127
Pubmed

Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.

MUC16 MUC12

4.75e-053139226770020
Pubmed

[A novel adaptor protein family regulating cytoskeletal organization and signal transduction--Vinexin, CAP/ponsin, ArgBP2].

SORBS1 SORBS3

4.75e-053139212510380
Pubmed

Lamin A mutation impairs interaction with nucleoporin NUP155 and disrupts nucleocytoplasmic transport in atrial fibrillation.

NUP155 LMNA

4.75e-053139230488537
Pubmed

A novel mutation in helix 12 of the vitamin D receptor impairs coactivator interaction and causes hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia.

NCOA1 VDR

4.75e-053139212403843
Pubmed

The unique tryptophan residue of the vitamin D receptor is critical for ligand binding and transcriptional activation.

NCOA1 VDR

4.75e-053139211149488
Pubmed

Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).

MUC16 MUC4

4.75e-053139227483328
Pubmed

Association of single nucleotide polymorphisms in CACNA 1A/CACNA 1C/CACNA 1H calcium channel genes with diabetic peripheral neuropathy in Chinese population.

CACNA1A CACNA1H

4.75e-053139229581247
Pubmed

MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.

MUC16 MUC4

4.75e-053139224204560
Pubmed

Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.

MUC16 MUC4

4.75e-053139224939955
Pubmed

Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.

MARK3 CDK14

4.75e-053139225028520
Pubmed

DUSP28 links regulation of Mucin 5B and Mucin 16 to migration and survival of AsPC-1 human pancreatic cancer cells.

MUC16 MUC5B

4.75e-053139227230679
Pubmed

Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.

MUC16 MUC4

4.75e-053139217592322
Pubmed

The vitamin D receptor interacts preferentially with DRIP205-like LxxLL motifs.

NCOA1 VDR

4.75e-053139217254542
Pubmed

Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.

MUC16 MUC4

4.75e-053139235879412
Pubmed

Regulation of ligand-induced heterodimerization and coactivator interaction by the activation function-2 domain of the vitamin D receptor.

NCOA1 VDR

4.75e-053139211075811
Pubmed

AMPK-mediated AS160 phosphorylation in skeletal muscle is dependent on AMPK catalytic and regulatory subunits.

TBC1D4 PRKAA2

4.75e-053139216804075
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DOCK4 LARP1 NFASC NUP155 MACF1

5.52e-0510113959872452
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

GATAD2A EP400 CAMSAP3 POGZ BPTF KMT2C

5.94e-05167139620362541
Pubmed

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.

SHB DGKH SORCS1 EYS

7.64e-0556139423934736
Pubmed

MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity.

MARK3 TBC1D4 MACF1 ARHGEF2

8.19e-0557139429089450
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

ZSWIM8 ABI1 TTLL5 APC2 VWCE DLGAP3 BEND7 SORBS3 TCF25 LTBP4

9.01e-055601391021653829
Pubmed

Crucial roles for interactions between MLL3/4 and INI1 in nuclear receptor transactivation.

KMT2B KMT2C

9.47e-054139219221051
Pubmed

Adult loss of Cacna1a in mice recapitulates childhood absence epilepsy by distinct thalamic bursting mechanisms.

CACNA1A CACNA1H

9.47e-054139231800012
Pubmed

The Eps8 protein coordinates EGF receptor signalling through Rac and trafficking through Rab5.

ABI1 USP6NL

9.47e-054139211099046
Pubmed

Anchorage of microtubule minus ends to adherens junctions regulates epithelial cell-cell contacts.

CAMSAP3 KIFC3

9.47e-054139219041755
Pubmed

ATXN3, ATXN7, CACNA1A, and RAI1 Genes and Mitochondrial Polymorphism A10398G Did Not Modify Age at Onset in Spinocerebellar Ataxia Type 2 Patients from South America.

CACNA1A RAI1

9.47e-054139225869926
Pubmed

Sympathetic inputs regulate adaptive thermogenesis in brown adipose tissue through cAMP-Salt inducible kinase axis.

SIK1 GNAS

9.47e-054139230030465
Pubmed

Agonist-triggered modulation of the activated and silent state of the vitamin D(3) receptor by interaction with co-repressors and co-activators.

NCOA1 VDR

9.47e-054139211124027
Pubmed

TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.

MUC16 MUC4

9.47e-054139239024979
Pubmed

Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism.

SIK1 GNAS

9.47e-054139229941929
Pubmed

p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer.

NCOA1 VDR

9.47e-054139227728806
Pubmed

Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex.

SRCIN1 SORBS3

9.47e-054139218662323
Pubmed

The sorbin homology domain: a motif for the targeting of proteins to lipid rafts.

SORBS1 SORBS3

9.47e-054139211481476
Pubmed

A subset of mixed lineage leukemia proteins has plant homeodomain (PHD)-mediated E3 ligase activity.

KMT2B KMT2C

9.47e-054139223129768
Pubmed

1alpha,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1alpha,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex.

NCOA1 VDR

9.47e-054139217786964
Pubmed

Functional importance of L- and P/Q-type voltage-gated calcium channels in human renal vasculature.

CACNA1A CACNA1H

9.47e-054139221788606
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

EXPH5 ZDHHC8 NUP155 RAB11FIP5 KIRREL1 MACF1 USP6NL

9.53e-05263139734702444
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

JCAD ABI1 MARK3 SIPA1L3 SHB LARP1 SORBS1 SRCIN1 MACF1 USP6NL

9.69e-055651391025468996
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

MARK3 SIPA1L3 LARP1 TBC1D4 LMNA ARHGEF2

1.21e-04190139615161933
Pubmed

Klf4 glutamylation is required for cell reprogramming and early embryonic development in mice.

TTLL5 AGBL5 AGBL3

1.35e-0425139329593216
Pubmed

Identification of preferred protein interactions by phage-display of the human Src homology-3 proteome.

SORBS1 SORBS3 ARHGEF6

1.35e-0425139316374509
Pubmed

Thr176 regulates the activity of the mouse nuclear receptor CAR and is conserved in the NR1I subfamily members PXR and VDR.

NCOA1 VDR

1.57e-045139215610065
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC4

1.57e-045139211062147
Pubmed

The EBAX-type Cullin-RING E3 ligase and Hsp90 guard the protein quality of the SAX-3/Robo receptor in developing neurons.

ZSWIM8 ROBO3

1.57e-045139224012004
Pubmed

Ternary complexes and cooperative interplay between NCoA-62/Ski-interacting protein and steroid receptor coactivators in vitamin D receptor-mediated transcription.

NCOA1 VDR

1.57e-045139211514567
Pubmed

Eyes absent: a gene family found in several metazoan phyla.

EYA1 NFATC2

1.57e-04513929195991
Pubmed

Normal function of the transcription factor NFAT1 in wasted mice. Chromosome localization of NFAT1 gene.

NFATC2 GNAS

1.57e-04513928973343
Pubmed

Lysine 246 of the vitamin D receptor is crucial for ligand-dependent interaction with coactivators and transcriptional activity.

NCOA1 VDR

1.57e-045139210224118
Pubmed

2-Methylene-19-nor-(20S)-1,25-dihydroxyvitamin D3 potently stimulates gene-specific DNA binding of the vitamin D receptor in osteoblasts.

NCOA1 VDR

1.57e-045139212796488
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

EP400 SORBS1 TBC1D4 MACF1 BICRAL

1.82e-04130139512421765
Pubmed

Identification of 14-3-3epsilon substrates from embryonic murine brain.

MARK3 SRCIN1 FRMD4B DLGAP3 TBC1D4

1.95e-04132139516944949
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MRPS31 DOCK4 CACNA1A JCAD ABI1 MAP1A CAMSAP3 SORBS1 SRCIN1 DLGAP3 LMNA RNF10 TCF25 MACF1

1.98e-0411391391436417873
InteractionYWHAE interactions

PABIR1 JCAD ABI1 MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SIK1 SORBS1 SRCIN1 CCDC6 CDK14 GLCCI1 FRMD4B USP31 RIN1 DLGAP3 MIDN TBC1D4 NFATC2 AMOTL1 TCF25 MIEF1 RAB11FIP5 MACF1 ARHGEF2 SRRM2 ARHGAP45 USP6NL

9.64e-10125613630int:YWHAE
InteractionYWHAG interactions

PABIR1 DOCK4 JCAD ABI1 MARK3 EXPH5 SIPA1L3 SHB CAMSAP3 LARP1 SIK1 SORBS1 CCDC6 CDK14 GLCCI1 USP31 RIN1 TBC1D4 LMNA NFATC2 TCF25 MIEF1 RAB11FIP5 MACF1 GNAS ARHGEF2 SRRM2 USP6NL ARHGEF6

3.63e-09124813629int:YWHAG
InteractionYWHAH interactions

PABIR1 DOCK4 JCAD ABI1 MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SIK1 SORBS1 CCDC6 CDK14 GLCCI1 USP31 RIN1 TBC1D4 PRKAA2 RNF10 MIEF1 NCOA1 RAB11FIP5 MACF1 ARHGEF2 SRRM2 USP6NL ARHGEF6

4.55e-09110213627int:YWHAH
InteractionYWHAZ interactions

PABIR1 JCAD ABI1 MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SIK1 SORBS1 CCDC6 CDK14 GLCCI1 USP31 RIN1 TBC1D4 LMNA NFATC2 NBEAL2 AMOTL1 PRKAA2 TCF25 MIEF1 RAB11FIP5 MACF1 ARHGEF2 USP6NL ARHGEF6

4.94e-08131913628int:YWHAZ
InteractionYWHAB interactions

PABIR1 DOCK4 MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SIK1 SORBS1 CCDC6 CDK14 GLCCI1 USP31 RIN1 TBC1D4 NFATC2 PRKAA2 TCF25 MIEF1 RAB11FIP5 MACF1 ARHGEF2 SRRM2 USP6NL

7.18e-08101413624int:YWHAB
InteractionSFN interactions

PABIR1 JCAD MAP1A MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SORBS1 TEX14 USP31 TBC1D4 LMNA PRKAA2 MIEF1 MACF1 ARHGEF2 SRRM2 USP6NL

2.09e-0769213619int:SFN
InteractionYWHAQ interactions

PABIR1 JCAD ABI1 MARK3 EXPH5 SIPA1L3 CAMSAP3 LARP1 SIK1 SORBS1 CCDC6 CDK14 GLCCI1 USP31 TBC1D4 LMNA NFATC2 MIEF1 NCOA1 MACF1 ARRDC3 ARHGEF2 USP6NL

1.61e-06111813623int:YWHAQ
InteractionAFDN interactions

JCAD MARK3 SIPA1L3 SHB SORBS1 FRMD4B RIN1 AMOTL1 SORBS3 KIRREL1 MACF1 USP6NL

2.76e-0633313612int:AFDN
InteractionCXADR interactions

JCAD MARK3 SIPA1L3 SHB SORBS1 MIDN NUP155 NCOA1 RAB11FIP5 KIRREL1 MACF1 USP6NL

7.86e-0636913612int:CXADR
InteractionMAPRE3 interactions

DOCK4 MAP1A MARK3 SIPA1L3 APC2 CAMSAP3 TTBK2 MACF1 ARHGEF2

2.68e-052301369int:MAPRE3
InteractionPARD3 interactions

JCAD MARK3 SIPA1L3 SORBS1 ZDHHC8 AMOTL1 PRKAA2 KIRREL1 ARRDC3 USP6NL

3.54e-0529813610int:PARD3
CytobandEnsembl 112 genes in cytogenetic band chr19p13

CACNA1A GATAD2A APC2 CAMSAP3 MUC16 B3GNT3 ADAMTS10 PRAM1 MIDN ARHGAP45

1.68e-0479713910chr19p13
GeneFamilyCD molecules|Mucins

MUC16 MUC5B MUC12 MUC4

2.44e-0621844648
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

OBSCN FSTL4 NFASC KIRREL1 SIGLEC11 SIGLEC1 ROBO3

9.93e-06161847593
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

KIRREL1 SIGLEC11 SIGLEC1

8.44e-0440843592
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

DOCK4 JCAD SPAG4 ABI1 MAP1A TTLL5 SHB NFASC SIK1 SORBS1 SRCIN1 FRMD4B AFAP1 PER3 SORBS3 ARRDC3 TNR USP6NL IQCE VDR

1.22e-06110213720M2369
CoexpressionGOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN

DOCK4 JCAD SPAG4 ABI1 MAP1A TTLL5 SHB NFASC SIK1 SORBS1 SRCIN1 FRMD4B AFAP1 PER3 SORBS3 ARRDC3 TNR USP6NL IQCE VDR

1.65e-06112413720MM1070
CoexpressionSRC_UP.V1_DN

NID2 B3GNT3 FRMD4B RRN3 MACF1 DISP2 ARRDC3 MN1

3.26e-061701378M2713
CoexpressionPEREZ_TP53_TARGETS

DOCK4 ABCA12 APC2 OBSCN FRMD8 ECE1 VWCE GLCCI1 HEPACAM BEND7 AMOTL1 AUTS2 INSM2 DISP2 GNAS CAMTA1 MN1 USP6NL ARHGEF6 VDR

4.48e-06120113720M4391
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

AHI1-DT KMT2B SIPA1L3 LARP1 FRMD4B SORCS1 PCDH15 TCF25 KIFC3 SRRM2 VDR

1.28e-0541713711M39224
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VWA5B2 ATG9B SPAG4 LARP1 TTBK2 TCF25 DISP2 CAMTA1

7.45e-0817313987e3897868dd3f6e4974f593c60649a543ffc8693
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CACNA1A FSTL4 NFASC EYS PCDH15 SCT CACNA1H

8.14e-081751398182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCellGlobus_pallidus-Neuronal-Inhibitory|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VWA5B2 ATG9B SPAG4 LARP1 TTBK2 TCF25 DISP2 CAMTA1

1.10e-07182139804ccfa951eaa31fed6d140edb6c702d49363c5fa
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

BPTF KMT2C NFATC2 SYTL3 NCOA1 GNAS SRRM2 ARHGAP45

1.94e-0719613987bced0cc2112697593c478fa291b8ed3941fb811
ToppCellAT1-AT2_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ABCA12 B3GNT3 ECE1 GLCCI1 AFAP1 BEND7 MUC4

6.67e-0715813973bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CACNA1A FSTL4 NFASC EYS SCT CACNA1H

1.27e-0617413979f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 CACNA1A NFASC SCT KIRREL1 DISP2 CACNA1H

1.48e-06178139730ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC16 DGKH MUC5B PRKAA2 MACF1 MUC4 RAI1

1.54e-0617913976e965e424eebef50f0202cff75f458be395cfca1
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOCK4 JCAD FRMD8 SORBS1 USP31 ADAMTS9 MACF1

1.60e-061801397493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD POGZ B3GNT3 ZDHHC8 AGBL3 AFAP1 BEND7

1.60e-0618013977368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellRV|World / Chamber and Cluster_Paper

MARK3 OBSCN SORBS1 EYA1 RBM20 TBC1D4 PRKAA2

1.66e-061811397bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AHI1-DT SIPA1L3 EYA1 GLCCI1 TBC1D4 ADAMTS9 KIRREL1

2.13e-06188139763a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

ABI1 ECE1 FRMD4B USP31 LMNA AMOTL1 LTBP4

2.29e-0619013974f15842b424eefadbfe451875e517cf70e29607f
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

GATAD2A DGKH LMNA NFATC2 SYTL3 EEPD1 MACF1

2.45e-0619213978b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo-Tgd_CRTAM|Liver / Manually curated celltypes from each tissue

GLCCI1 MIDN LMNA SYTL3 AUTS2 GNAS SRRM2

2.72e-061951397972b09697b7b66fb8a27dfc0c0b05a844121f055
ToppCell10x5'-Liver-Lymphocytic_T_CD4/8-lo|Liver / Manually curated celltypes from each tissue

GLCCI1 MIDN LMNA SYTL3 AUTS2 GNAS SRRM2

2.72e-061951397c29c4ae95a756e3ced0f0747bbfe343590e5b8ab
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 NFASC SORBS1 RIN1 LMNA NFATC2 LTBP4

2.90e-06197139785a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NID2 NFASC SORBS1 RIN1 LMNA NFATC2 LTBP4

2.90e-061971397e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 EYA1 STOX1 ECE1 EEPD1 PRKAA2 SORBS3

3.00e-06198139728ada093cec552262731194a04a4b9ff93186c3b
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

OBSCN FSTL4 SIK1 DGKH EYA1 USP31 MUC4

3.00e-0619813975374b0e98d669f36a0571d3c006c7bd5e3c8e87f
ToppCellLung_Parenchyma-Severe|Lung_Parenchyma / Location, Disease Group, Cell group, Cell class (2021.03.09)

NID2 SPAG4 MUC16 MUC5B C1QTNF6 ARRDC3 MUC4

3.21e-06200139762502bb23ca732daed32c838ce9719093f3aaeb0
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

ABI1 STOX1 EYS EEPD1 BEND7 PCDH15

4.23e-0613513963351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1A ABCA12 SORCS1 EYS PCDH15 TNR

5.00e-061391396a1945b07f177cde40e7eea03a19236ce76165857
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CATIP STOX1 CDK14 KIRREL1 C1QTNF6 LTBP4

5.21e-061401396e442c46979d725ec82f525a001c46d971fcade4d
ToppCellAT1-AT2_cells-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CACNA1A EXPH5 APC2 SIK1 ADAMTS9 NBEAL2

5.21e-06140139645d52a086ced8d58e01ac51ac4a90338e8649b16
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related-Oligodendrocyte/OPC|GW10 / Sample Type, Dataset, Time_group, and Cell type.

NID2 SHB FSTL4 AGBL3 TESMIN GPR156

8.04e-0615113964533bccc996395f74b16af939ce79b6fe253c073
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-OPC_related|GW10 / Sample Type, Dataset, Time_group, and Cell type.

NID2 SHB FSTL4 AGBL3 TESMIN GPR156

8.04e-061511396edb2f59789c295838d2030b80c792cbea25eaa3d
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

GATAD2A SIPA1L3 LARP1 SRRM2 MUC4 IQCE

1.08e-051591396655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1A FSTL4 NFASC DGKH ADAMTS9 CACNA1H

1.12e-05160139629c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZC3H12B GLCCI1 FRMD4B PCDH15 KANK4 MACF1

1.12e-0516013960293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

ZC3H12B GLCCI1 FRMD4B PCDH15 KANK4 MACF1

1.12e-0516013963eaae86fa08f7651021316f8e5811bf48055591e
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2B MAP1A AGBL5 TTBK2 MIEF1 INSM2

1.24e-051631396953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

MUC5B EYA1 B3GNT3 ADAMTS10 PRKAA2 MUC4

1.43e-0516713966efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCell3'-Child04-06-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CACNA1A SRCIN1 EYS SCT C1QTNF6

1.43e-0516713965accd0bc7c95089feb2c09376d12cd8bd3773775
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 CACNA1A EYS SCT DISP2 TNR

1.48e-0516813960f736d58cb0ff042fa3ce58e36bde37b6976f8fc
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

LILRB2 OBSCN FRMD4B RBM20 PRKAA2 SIGLEC1

1.58e-0517013964232fe937909f93d3736988c707b8f95ce993398
ToppCellLV-13._Vascular_Smooth_Muscle|LV / Chamber and Cluster_Paper

CACNA1A FSTL4 NFASC DGKH ADAMTS9 KIRREL1

1.63e-051711396e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell343B-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AHI1-DT SHB LARP1 ZDHHC8 USP31 AMOTL1

1.69e-051721396eb199c279fe8a2551121db37e9556893197d33ff
ToppCell343B-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

AHI1-DT SHB LARP1 ZDHHC8 USP31 AMOTL1

1.69e-051721396709c6b77a7a52b873eefb6caca28a41291d384af
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B EYA1 STOX1 PRKAA2 MUC4

1.74e-051731396464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1A NFASC SORBS1 ADAMTS9 KIRREL1 CACNA1H

2.11e-051791396a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellCD8+_Memory_T_cell-FLU-5|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

CFAP20DC TBC1D4 LMNA TESMIN USP6NL VDR

2.11e-0517913967f18dffa85285599662edbcd3f32ab42672bffb8
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHB SORBS1 LMNA ADAMTS9 CACNA1H LTBP4

2.18e-051801396af2bafcd1b2082629de3ea336711add01565c4c4
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHB SORBS1 LMNA ADAMTS9 CACNA1H LTBP4

2.18e-051801396f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

CACNA1A NFASC DLGAP3 ADAMTS9 KIRREL1 CACNA1H

2.25e-0518113968dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AHI1-DT DGKH CDK14 GLCCI1 KIRREL1 VDR

2.25e-05181139622363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

CACNA1A NFASC DLGAP3 ADAMTS9 KIRREL1 CACNA1H

2.32e-0518213962075efeae633550fb2eb026d0dfd741c8252482e
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MUC16 MUC5B EYA1 STOX1 PRKAA2 MUC4

2.32e-0518213963f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN MUC5B FREM1 SORCS1 PCDH15

2.47e-0518413962cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK4 GATAD2A DGKH USP31 ADAMTS9 CAMTA1

2.47e-051841396c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN MUC5B FREM1 SORCS1 PCDH15

2.47e-051841396ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 OBSCN MUC5B FREM1 SORCS1 PCDH15

2.47e-0518413962b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LILRB2 PRAM1 LMNA NBEAL2 TCF25 SRRM2

2.47e-051841396bc0dfe29337f02594e7e0092c9e47dda94b45ad5
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

DGKH GLCCI1 FRMD4B TBC1D4 JAZF1 VDR

2.54e-051851396e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 CACNA1A NFASC SCT DISP2 CACNA1H

2.54e-0518513962a8104f610fa5ce618f8105521616722462a0d42
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

OBSCN NFASC DGKH ECE1 ADAMTS9 CACNA1H

2.70e-051871396a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A JCAD AMOTL1 KANK4 LTBP4 MN1

2.78e-051881396ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTS9 NBEAL2 BEND7 KIFC3 MUC4 USP6NL

2.78e-05188139643a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

OBSCN DGKH ECE1 ADAMTS9 KIRREL1 CACNA1H

2.87e-051891396d7ed96add29f219183c802895fbff519b627f635
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NID2 OBSCN DGKH ECE1 ADAMTS9 CACNA1H

2.95e-0519013964eb92aef1ee868f4537483d19014d947b7684612
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A MUC16 MUC12 CFAP20DC TESMIN MUC4

2.95e-0519013960adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NFASC DGKH SORBS1 RBM20 ADAMTS9 CACNA1H

2.95e-051901396d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NID2 OBSCN DGKH ECE1 ADAMTS9 CACNA1H

2.95e-0519013967be4341e2909101d756f14031c21e705eb45e69a
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A MUC16 MUC12 CFAP20DC TESMIN MUC4

2.95e-05190139605455775845f4ded5c27e7b83242078d23162aaf
ToppCellCOPD-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

DGKH GLCCI1 FRMD4B TBC1D4 JAZF1 VDR

3.04e-0519113963ae18bc4e3dff49b5d5958da8ebc3f747274b69c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SORBS1 LMNA NFATC2 JAZF1 LTBP4 MN1

3.04e-0519113962c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NFASC SORBS1 ECE1 RBM20 SORBS3 CACNA1H

3.04e-05191139604c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

NFASC DGKH SORBS1 RBM20 ADAMTS9 CACNA1H

3.04e-051911396fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APC2 OBSCN ECE1 RIN1 AMOTL1 LTBP4

3.13e-0519213961990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF337 LARP1 DGKH AFAP1 MACF1 CACNA1H

3.13e-051921396930319cbd82b9e54864147ffcdc8bd0ea7b937be
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 OBSCN RBM20 TBC1D4 PRKAA2 CACNA1H

3.13e-0519213960bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF337 LARP1 DGKH AFAP1 MACF1 CACNA1H

3.13e-051921396c7bcebcb88a25b2c97d798120efa9d5958e7f798
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APC2 OBSCN ECE1 RIN1 AMOTL1 LTBP4

3.13e-051921396845cc9c18b4436b07dd3ce7980052683937546d2
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial-vein_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

APC2 OBSCN ECE1 RIN1 AMOTL1 LTBP4

3.13e-051921396c72a082c93a8825adbfef37f889ba3a7052f201b
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR9 OBSCN RBM20 TBC1D4 PRKAA2 CACNA1H

3.13e-051921396d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellClub_cells|World / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B B3GNT3 ECE1 PRKAA2 MUC4

3.22e-0519313969d3165dc5763a07a7d873f497624d9d6528fa2db
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-NK-NK-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EP400 DGKH AFAP1 SYTL3 MACF1 CACNA1H

3.32e-0519413963211d89440a6f4a9b3d4cfb755890816944242ec
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

LILRB2 PRAM1 MIDN NBEAL2 TCF25 SRRM2

3.32e-051941396a94f9f7179a5733e3c378ff8b337e288785433a1
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MUC16 MUC5B B3GNT3 ECE1 PRKAA2 MUC4

3.42e-051951396b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A KMT2C NCOA1 MACF1 SRRM2 VDR

3.42e-0519513963e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Limb_Muscle-MUSCLE-1m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMD4B PER3 NFATC2 RNF10 C1QTNF6 ARRDC3

3.42e-051951396fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B EYA1 B3GNT3 CDK14 MUC4

3.42e-051951396e7230a849ea31e6eef9bc6f5468938499450582d
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A KMT2C NCOA1 MACF1 SRRM2 VDR

3.42e-0519513967796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCV-Moderate-6|Moderate / Virus stimulation, Condition and Cluster

KMT2C NFATC2 SYTL3 NCOA1 SRRM2 ARHGAP45

3.42e-0519513962b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

B3GNT3 CDK14 GLCCI1 AUTS2 KIFC3 MUC4

3.52e-051961396ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 CDK14 FRMD4B FREM1 MACF1 LTBP4

3.52e-0519613961450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FRMD4B FREM1 AFAP1 AMOTL1 PCDH15 KIRREL1

3.52e-0519613967af6c5147ac859353504d19727dbe24f63a29dd4
ToppCellfacs-Brain_Non-Myeloid|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD MAP1A NFASC SORBS1 HEPACAM SORBS3

3.62e-051971396a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

OBSCN DGKH EYA1 ECE1 USP31 MUC4

3.62e-0519713961e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA12 MUC16 MUC5B EYA1 PRKAA2 MUC4

3.72e-051981396de5987588b9fa9ee8c595ba06d7d844ead0e3c74
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1A NFASC SORBS1 ADAMTS10 ADAMTS9 CACNA1H

3.72e-0519813967dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

DOCK4 STOX1 FREM1 SORCS1 MACF1 LTBP4

3.72e-0519813960c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MUC16 MUC5B EYA1 STOX1 PRKAA2 MUC4

3.72e-051981396af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellCOPD-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

DOCK4 SIK1 FRMD4B SYTL3 EEPD1 ARRDC3

3.83e-0519913961cf1b2d6debf9e3389f1829dcaa2857e9533a080
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

OBSCN FSTL4 DGKH EYA1 USP31 MUC4

3.83e-05199139694a7867e800df352731796de8c24cba133c29622
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NID2 CDK14 FREM1 AFAP1 MACF1 LTBP4

3.83e-051991396a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellTransverse-T_cell-Tfh|Transverse / Region, Cell class and subclass

ATG9B OBSCN DGKH PER3 NBEAL2 RAB11FIP5

3.83e-051991396cbef8f95edf2e86e16c448a76068d7ed8f6b7748
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MUC5B SORBS1 FREM1 KANK4 DISP2 LTBP4

3.83e-05199139645c3b853900d8c3d5965117d904e3714100138bc
ToppCellTransverse-(1)_T_cell-(16)_Tfh|Transverse / shred on region, Cell_type, and subtype

ATG9B OBSCN DGKH PER3 NBEAL2 RAB11FIP5

3.83e-051991396aa31e26d48066f865ca33251a33a28934c0a7a44
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DOCK4 CDK14 FREM1 AFAP1 MACF1 LTBP4

3.83e-05199139630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
DrugFluticasone propionate [80474-14-2]; Up 200; 8uM; MCF7; HT_HG-U133A

ZNF337 SIPA1L3 SIK1 CDK14 RIN1 TBC1D4 SRRM2 VDR

2.18e-0519213784129_UP
DrugThiamine hydrochloride [67-03-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A

KMT2B SIPA1L3 ECE1 USP19 SORBS3 RAB11FIP5 ARHGEF2 VDR

2.27e-0519313782894_DN
DrugDoxazosin mesylate [77883-43-3]; Up 200; 7.4uM; MCF7; HT_HG-U133A

MAP1A LILRB2 TEX14 CCDC6 ADAMTS9 PRKAA2 KIFC3 ARHGEF2

2.35e-0519413783363_UP
DrugCefoperazone dihydrate; Down 200; 5.8uM; MCF7; HT_HG-U133A

ZSWIM8 KMT2B B3GNT3 TTBK2 TBC1D4 LMNA SORBS3 ARHGEF2

2.44e-0519513785424_DN
DrugTetramisole hydrochloride [16595-80-5]; Down 200; 16.6uM; PC3; HT_HG-U133A

CACNA1A TTLL5 SIPA1L3 USP19 RIN1 TBC1D4 SRRM2 MN1

2.53e-0519613784587_DN
DrugAceclofenac [89796-99-6]; Down 200; 11.2uM; PC3; HT_HG-U133A

MUC5B AFAP1 NBEAL2 SORBS3 NCOA1 BICRAL GNAS ARHGAP45

2.53e-0519613787269_DN
DrugGuanabenz acetate [23256-50-0]; Up 200; 13.8uM; MCF7; HT_HG-U133A

JCAD SPAG4 ABCA12 INKA2 PER3 NBEAL2 CACNA1H KIFC3

2.72e-0519813781544_UP
DrugBenzocaine [94-09-7]; Down 200; 24.2uM; MCF7; HT_HG-U133A

SPAG4 EXPH5 SIPA1L3 RIN1 TTBK2 LMNA ROBO3 USP6NL

2.72e-0519813784808_DN
DrugEtomidate [33125-97-2]; Up 200; 16.4uM; MCF7; HT_HG-U133A

DOCK4 INKA2 RIN1 AFAP1 TESMIN PRKAA2 GNAS ARHGEF2

2.72e-0519813783519_UP
DrugIsopropamide iodide [71-81-8]; Down 200; 8.4uM; PC3; HT_HG-U133A

KMT2B ZNF337 TTLL5 MUC5B TTBK2 TBC1D4 BICRAL VDR

2.82e-0519913787133_DN
DrugAustricine [10180-88-8]; Down 200; 14.2uM; HL60; HT_HG-U133A

CACNA1A SHB ECE1 USP19 PER3 LMNA NBEAL2 RAB11FIP5

2.93e-0520013782157_DN
Diseasemental or behavioural disorder, attempted suicide

JCAD SORBS1

2.03e-0451342EFO_0000677, EFO_0004321
Diseasemigraine disorder

DOCK4 CACNA1A JCAD SORBS1 EYA1 RBM20 MACF1 CAMTA1

2.36e-043571348MONDO_0005277
Diseaseprostate carcinoma, breast carcinoma, ovarian carcinoma

GATAD2A RIN1 JAZF1

2.47e-04271343EFO_0000305, EFO_0001075, EFO_0001663
DiseaseAkinetic Petit Mal

CACNA1A CACNA1H

4.24e-0471342C0001890
DiseaseEpilepsy, Absence, Atypical

CACNA1A CACNA1H

4.24e-0471342C0751124
DiseaseAbsence Seizure Disorder

CACNA1A CACNA1H

4.24e-0471342C4553705
DiseaseJuvenile Absence Epilepsy

CACNA1A CACNA1H

4.24e-0471342C4317339
DiseaseChildhood Absence Epilepsy

CACNA1A CACNA1H

4.24e-0471342C4281785
DiseaseEpilepsy, Minor

CACNA1A CACNA1H

4.24e-0471342C4552765
DiseaseAbsence Epilepsy

CACNA1A CACNA1H

4.24e-0471342C0014553
DiseasePR interval

DOCK4 ABCA12 MARK3 OBSCN ZFPM1 FRMD4B BEND7 MACF1 CAMTA1

4.49e-044951349EFO_0004462
Diseasepeak expiratory flow

JCAD ZC3H12B ADAMTS10 EYS JAZF1 NCOA1 LTBP4 MN1 VDR

4.68e-044981349EFO_0009718
Diseasemean corpuscular hemoglobin concentration

MRPS31 FOXK2 GATAD2A EP400 MARK3 LARP1 ZFPM1 ECE1 FRMD4B TTBK2 TBC1D4 MACF1 ARRDC3 MN1

5.17e-04110513414EFO_0004528
DiseaseLiver Diseases, Parasitic

KMT2C GNAS

7.22e-0491342C0023897
Diseaseeye color

MUC16 SIK1 EYS JAZF1

7.68e-04901344EFO_0003949
Diseaseotitis media (is_marker_for)

MUC5B MUC4

8.99e-04101342DOID:10754 (is_marker_for)
DiseaseIntellectual Disability

APC2 POGZ BPTF KMT2C MACF1 GNAS MN1 RAI1

1.03e-034471348C3714756
DiseaseC-reactive protein measurement

DOCK4 ZSWIM8 AHI1-DT MAP1A DGKH ZFPM1 AGBL5 BPTF EEPD1 RNF10 PCDH15 JAZF1 MACF1 CAMTA1

1.20e-03120613414EFO_0004458
Diseasenon-alcoholic fatty liver disease

GATAD2A EYA1 BPTF KANK4 JAZF1

1.49e-031821345EFO_0003095
Diseasedisease recurrence, colon carcinoma

FRMD4B AMOTL1 MACF1

1.63e-03511343EFO_0004952, EFO_1001950
DiseasePre-Eclampsia

STOX1 ARHGAP45

2.36e-03161342C0032914
Diseaseplatelet component distribution width

JCAD MARK3 TRMO ZFPM1 MACF1 SIGLEC1 ARRDC3 GNAS CAMTA1 IQCE

2.40e-0375513410EFO_0007984
Diseasemigraine disorder, type 2 diabetes mellitus

EYA1 INKA2 AFAP1

2.59e-03601343MONDO_0005148, MONDO_0005277
Diseaseautosomal dominant intellectual developmental disorder (is_implicated_in)

KMT2B SRRM2

2.66e-03171342DOID:0060307 (is_implicated_in)
DiseaseTachycardia

SCT GNAS

2.99e-03181342C0039231
DiseaseTachyarrhythmia

SCT GNAS

2.99e-03181342C0080203
Diseasesquamous cell carcinoma (is_implicated_in)

KMT2C VDR

2.99e-03181342DOID:1749 (is_implicated_in)
Diseasehair color

LINC00322 MARK3 SIK1 CDK14 TCF25 JAZF1

3.04e-033111346EFO_0003924
Diseaseserum gamma-glutamyl transferase measurement

JCAD MAP1A SIPA1L3 ZFPM1 BPTF EYS NBEAL2 JAZF1 SIGLEC1 ARHGEF2 USP6NL

3.08e-0391413411EFO_0004532
Diseasecholangiocarcinoma (is_marker_for)

MUC16 MUC5B MUC4

3.12e-03641343DOID:4947 (is_marker_for)
Diseasecomparative body size at age 10, self-reported

GATAD2A DGKH ECE1 ADAMTS10 GNAS ARHGEF2 CAMTA1

3.15e-034201347EFO_0009819
Diseaseeosinophil count

SIPA1L3 DGKH ZFPM1 STOX1 ECE1 ZDHHC8 GLCCI1 BPTF TBC1D4 NFATC2 CACNA1H ARHGAP45 LTBP4 RAI1 VDR

3.17e-03148813415EFO_0004842
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

ECE1 NFATC2 ADAMTS9 JAZF1 AUTS2

3.44e-032211345C0011860
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

JCAD ABI1 NFASC CDK14 BPTF BEND7 PCDH15 AUTS2 BICRAL CAMTA1

3.66e-0380113410EFO_0003888, EFO_0007052, MONDO_0002491
DiseaseMalignant neoplasm of breast

NID2 APC2 OBSCN SORBS1 SORCS1 PER3 BEND7 PRKAA2 NCOA1 MACF1 ARRDC3 VDR

3.67e-03107413412C0006142
Diseaseselenium measurement, response to dietary selenium supplementation

JAZF1 GPR156

3.69e-03201342EFO_0006331, EFO_0600021
DiseaseCraniosynostosis

FREM1 MN1

3.69e-03201342C0010278
Diseasesmoking cessation

ZSWIM8 USP19 PCDH15 AUTS2 CACNA1H CAMTA1

3.77e-033251346EFO_0004319
Diseasephospholipids:total lipids ratio

BPTF PRAM1 RRN3 KANK4 MACF1

3.86e-032271345EFO_0020946
Diseaselifestyle measurement

GATAD2A GLCCI1 FREM1 PCDH15 AUTS2

4.46e-032351345EFO_0010724
Diseaseceramide measurement

GATAD2A TTLL5 EYS PCDH15 ARHGAP45

4.46e-032351345EFO_0010222

Protein segments in the cluster

PeptideGeneStartEntry
HPSRPNSRHTPSFSG

VDR

166

P11473
SPDPTFRSSTRHSGK

GNAS

11

P84996
FLSSRVHPGETPSSF

AGBL5

246

Q8NDL9
RHASSGATGRSPRTP

CACNA1A

2441

O00555
RTVAFPSTHPPRTAA

EP400

1476

Q96L91
PGSRHSPASASRVAG

AGBL3

711

Q8NEM8
NIRHSPPGERSFSFT

CAMTA1

511

Q9Y6Y1
AHSSFSSTGQPRGPL

ARHGEF6

566

Q15052
RRHASLATVFPSPSS

ABCA12

131

Q86UK0
SAAGLHRPRSSFDST

PRKAA2

491

P54646
SGTSSPQSPVFRHRT

AFAP1

661

Q8N556
GSSRLSPPHSPRDFT

ARHGEF2

951

Q92974
SPARLGSQHSPGRTA

ABI1

216

Q8IZP0
ASLPSRGRLSTTPAH

AMOTL1

891

Q8IY63
RAPLPAHYRSSSTRS

GLCCI1

331

Q86VQ1
EVPGNRRSHPSLSFS

AHI1-DT

241

P0C7V0
SSSRPISPGLSYASH

CCDC6

361

Q16204
RRHSSPSSPTSPKFG

CDK14

116

O94921
PAHPTPASIFSARST

ANO9

766

A1A5B4
SHSTYSSTPGRRKPR

BPTF

196

Q12830
NSGSSSPVFTFRHPL

CAMSAP3

346

Q9P1Y5
SSSHNTLRPAPRGSA

DISP2

241

A7MBM2
FAERSRPPSTHTNGG

EEPD1

196

Q7L9B9
TIPLHPFGSRTSSVS

ARRDC3

311

Q96B67
HSTGRSPAPASLSLQ

ASTL

296

Q6HA08
GVSSSSRHCDSPRPT

ADAMTS10

566

Q9H324
GRSLSPSSPHTVRTA

MUC5B

2756

Q9HC84
LTTLRPTGFPSSHFS

MUC5B

4926

Q9HC84
SSSHSPARSVGRSPS

RAI1

341

Q7Z5J4
RSLSPRSHTPSFTSC

RBM20

641

Q5T481
PSPRTFHTSSAAIGN

RABEPK

136

Q7Z6M1
PVRHRSSISGSLPSS

RAB11FIP5

351

Q9BXF6
RRSASATHGDASSPP

IQCE

636

Q6IPM2
SRGSATTPRGVLHTF

GATAD2A

531

Q86YP4
TIPNFSHRGSDTAPS

MUC16

11591

Q8WXI7
GFTHRSSVAPTSTPG

MUC16

12971

Q8WXI7
TTGRPHERSSFSPGV

MUC4

461

Q99102
TFHPTLSEASTAGRP

MUC4

871

Q99102
PASRSSSPGAKRRHS

NFATC2

241

Q13469
HRPRTASISSSPSEG

LARP1

841

Q6PKG0
STPGHRRGSPISFLS

OR10AC1

86

Q8NH08
PSPTSQRSRGRASSH

LMNA

391

P02545
HPSRAFSQPGTISRP

KMT2C

2111

Q8NEZ4
TLGRSHRSPLTAASP

ARHGAP45

86

Q92619
RKSPASSFSHSTPSG

MAP1A

1286

P78559
FPTASRHLPFTRSLT

EYS

1851

Q5T1H1
QPSLGSSTKFPSHRS

INKA2

96

Q9NTI7
SSRSAPASPNHAGVL

FOXK2

366

Q01167
PGPAERSHRSSVSSV

FRMD8

11

Q9BZ67
PRGHGEPQSTSASRT

JCAD

76

Q9P266
SVSRGNVSTPPRHSS

JAZF1

91

Q86VZ6
SEGHPFITSRSSSPL

PER3

911

P56645
GSAIGSSSFSPRPTH

EYA1

66

Q99502
TSGSFHLERRPLPSS

FREM1

1886

Q5H8C1
GPFHGSVQTRASSPR

ZFPM1

116

Q8IX07
ARPSTLFSAAGAAHP

AUTS2

706

Q8WXX7
PHARGSSRAIFSVGP

LILRB2

171

Q8N423
SPRRHVATIFPQSGS

EXPH5

1611

Q8NEV8
SGGTLAHTPRRSLPS

KMT2B

941

Q9UMN6
APTSPTRLSHSGKRS

MIEF1

56

Q9NQG6
PSARRNSTTFPSRHG

PABIR1

56

Q96E09
TAPRSPDARASYGHS

DGKH

681

Q86XP1
PSTFFSSPGLTRHIN

INSM2

531

Q96T92
RPTPTFHSSRTSLAG

MACF1

7271

Q9UPN3
TLVHVRLPPGFSASS

NUP155

386

O75694
ARNSHSAASRDPPAS

PAQR9

26

Q6ZVX9
SASPRHGRSRPSSSI

OBSCN

5571

Q5VST9
LRSYPASGHTTPLSR

NID2

446

Q14112
SHPSLPSERYRTSGA

NFASC

711

O94856
RPHFSFSTLPTVSRT

PCDH15

1666

Q96QU1
QRSRSHSRSASPFPS

PAF1

491

Q8N7H5
RRFSDSSGSLTPPGH

FAM189B

461

P81408
TFPGQRSSSVPHSPR

FRMD4B

596

Q9Y2L6
FPASRHGSPSRSARV

APC2

2256

O95996
PRSASPSRTHVLGGN

ADAMTS9

1316

Q9P2N4
GPSRFPAVSSASTAH

BICRAL

536

Q6AI39
LDPAHVSSASSSGRP

C1QTNF6

66

Q9BXI9
ARHTTSVSPSPAGRS

DOCK4

1801

Q8N1I0
PHSGSSRRESVSCSP

LINC00322

236

Q6ZN03
TPHTSPDGRFIVSAA

FSTL4

691

Q6MZW2
HPRSSIPGYSRSLTT

DLGAP3

446

O95886
SPALGSSHRPNPFRS

CATIP

361

Q7Z7H3
GRISIFSLSPAPHTR

ATG9B

46

Q674R7
PASHSGIRTSGVRAP

B3GNT3

311

Q9Y2A9
PRGTASRSTFHGQPR

MARK3

556

P27448
ATSRPSAGFLPTHRL

LTBP4

496

Q8N2S1
QRARSHFPGSAPSSV

GPR156

606

Q8NFN8
AGFHSSSPRASTRIP

KANK4

211

Q5T7N3
ARFDGRPSSRLSHSS

KIRREL1

631

Q96J84
ARSPATGRTHSSPPR

HEPACAM

366

Q14CZ8
SSAEAPQSLHPSSRG

BEND7

101

Q8N7W2
PHSPSRFRVIGSLSN

ECE1

731

P42892
HALSPRGTARSPSLS

CACNA1H

1996

O95180
APPRARRHSDGTFTS

SCT

21

P09683
SPNRAASFHGLPSSS

MN1

196

Q10571
SGLPRFSHDRRPSSC

TESMIN

436

Q9Y4I5
ASPSPITAGSFRSHA

MIDN

211

Q504T8
RHPLSSGSPETSAAA

MRPS31

16

Q92665
GITPSSFDTHFRSPS

RRN3

621

Q9NYV6
SSPAPSTIFSGGFRH

SYTL3

271

Q4VX76
SPSSFTTGHLAREKP

RIN1

16

Q13671
SGSPHLYRSSSERRP

SHB

156

Q15464
SRLLPRYSHSGSSSP

SRRM2

961

Q9UQ35
ATPPATRNHSGSRTP

SRRM2

2091

Q9UQ35
FTLSSHRQGPSASPS

TEX14

886

Q8IWB6
ARAHSAPSSGTSSRP

KIFC3

801

Q9BVG8
NPSISPAHGVARSST

NCOA1

391

Q15788
FNPSHRSSSILPRGL

POGZ

836

Q7Z3K3
RPFPAAPGRHSSSLS

NBEAL2

1396

Q6ZNJ1
SSLPAAVAGFSSRHP

PRAM1

391

Q96QH2
PTSTPASSGSKAFHR

SIPA1L3

126

O60292
PASRASRGGLSPFHA

SIK1B

616

A0A0B4J2F2
PASRASRGGLSPFHA

SIK1

616

P57059
STNHPGASIALSRPS

INIP

36

Q9NRY2
RPGSASSSRKHTPNF

SPAG4

6

Q9NPE6
DIFTFSSRPRSAPHG

CFAP20DC

351

Q6ZVT6
TGVFSTRSPHRPNAI

TRMO

111

Q9BU70
HRTRLFFPSSSGSAS

USP19

76

O94966
PSRRPHGSTLSVSAS

USP6NL

666

Q92738
PPTPGSGSRSRFSHR

RBMXL3

96

Q8N7X1
RSFPSSHGLTTTRTG

SRCIN1

1011

Q9C0H9
QTPHSLPSRGASFSD

STOX1

636

Q6ZVD7
LPSRGASFSDRTPSA

STOX1

641

Q6ZVD7
SFPHSEGLSGASSRP

ROBO3

936

Q96MS0
ALSISPLSRSPGSHA

RNF10

666

Q8N5U6
HSQPARASGSFAPIS

SORBS1

221

Q9BX66
PRTSSSSPSRAGRPH

TTBK2

1161

Q6IQ55
TSTAFTTGGRVFPHP

TNR

1121

Q92752
SRLSTALAATTHPGP

VWCE

926

Q96DN2
PQGTAPLTFSRRHSL

TEX13C

781

A0A0J9YWL9
AARSARHPSSPSALR

SORBS3

536

O60504
HSPRFSGTSGPNSLR

SIGLEC1

461

Q9BZZ2
FRRRAHTFSHPPSST

TBC1D4

636

O60343
NTRSASSPVPGSSHF

ZC3H12B

486

Q5HYM0
VLGSSRSSPPRAAGH

nan

201

A8MV72
SRPTTASQRSPSKHG

ZSWIM8

1031

A7E2V4
SPFAVHRASLSPTSA

VWA5B2

1091

Q8N398
ALGSSRSSPPRAAGH

nan

231

Q8N9G6
ALGSSRSSPPRAAGH

nan

231

A8MUA0
PASPLGRSHSSAGVR

ZNF843

81

Q8N446
SSGSHRSPARQGLPS

ZDHHC8

661

Q9ULC8
RSNSPSRFSGDSPIH

USP31

876

Q70CQ4
APRSASTPRGFSHQG

SORCS1

46

Q8WY21
VRPDASVSSHRFFGP

TCF25

471

Q9BQ70
AALSPRRTRPSTSHF

SIGLEC11

196

Q96RL6
RPSRISRTFFSPHQG

ZNF169

156

Q14929
PRCRSGSHTIGPFSS

TTLL5

961

Q6EMB2
AFSSPPLRHAVSSRR

ZNF337

131

Q9Y3M9
RFSSVSSPQPRSRHP

KIAA1522

336

Q9P206
RSPHTTLSPAGSTTR

MUC12

756

Q9UKN1
TSRSRPGSTHTTAFP

MUC12

996

Q9UKN1
AFPDSTTTPGLSRHS

MUC12

2091

Q9UKN1
HSSPGATGTALFPTR

MUC12

3196

Q9UKN1
SRPGSTHTTAFPGST

MUC12

3281

Q9UKN1