Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein N-acetylglucosaminyltransferase activity

OGT B3GNT8

3.58e-0521202GO:0016262
DomainAn_peroxidase

MPO DUOX2 LPO

3.00e-05101203PF03098
DomainHaem_peroxidase_animal

MPO DUOX2 LPO

3.00e-05101203IPR019791
DomainHaem_peroxidase

MPO DUOX2 LPO

3.00e-05101203IPR010255
DomainPEROXIDASE_3

MPO DUOX2 LPO

3.00e-05101203PS50292
Domain-

MPO DUOX2 LPO

3.00e-051012031.10.640.10
DomainARHGEF5_35

ARHGEF5 ARHGEF35

4.09e-0521202PF15441
DomainARHGEF5/35_N

ARHGEF5 ARHGEF35

4.09e-0521202IPR029212
DomainP-type_ATPase_IIA

ATP2A2 ATP2A3

1.22e-0431202IPR005782
DomainLaminin_G_2

CNTNAP3B COL11A2 GAS6 CNTNAP3

1.24e-04401204PF02210
DomainLamG

CNTNAP3B COL11A2 GAS6 CNTNAP3

1.80e-04441204SM00282
DomainLaminin_G

CNTNAP3B COL11A2 GAS6 CNTNAP3

5.26e-04581204IPR001791
DomainConA-like_dom

CNTNAP3B COL11A2 TRIM4 GAS6 CNTNAP3 TRIM14 TRIM69

5.37e-042191207IPR013320
DomainEGF_extracell

ADAM19 JAG1 LTBP2 NOTCH3

5.99e-04601204IPR013111
DomainEGF_2

ADAM19 JAG1 LTBP2 NOTCH3

5.99e-04601204PF07974
DomainPEROXIDASE_1

MPO LPO

6.04e-0461202PS00435
DomainhEGF

GAS6 JAG1 NOTCH3

7.54e-04281203PF12661
DomainEGF_3

CNTNAP3B ADAM19 GAS6 CNTNAP3 JAG1 LTBP2 NOTCH3

8.15e-042351207PS50026
DomainEGF-like_dom

CNTNAP3B ADAM19 GAS6 CNTNAP3 JAG1 LTBP2 NOTCH3

1.14e-032491207IPR000742
DomainEGF_1

CNTNAP3B ADAM19 GAS6 CNTNAP3 JAG1 LTBP2 NOTCH3

1.31e-032551207PS00022
DomainEGF

GAS6 CNTNAP3 JAG1 LTBP2 NOTCH3

1.32e-031261205PF00008
Domain-

INS INS-IGF2

1.43e-03912021.10.100.10
DomainEGF_2

CNTNAP3B ADAM19 GAS6 CNTNAP3 JAG1 LTBP2 NOTCH3

1.63e-032651207PS01186
DomainHydrolase_3

ATP2A2 ATP2A3

1.78e-03101202PF08282
DomainInsulin

INS INS-IGF2

1.78e-03101202PF00049
Domain-

B4GALNT4 A3GALT2 MGAT1 UAP1L1

1.84e-038112043.90.550.10
DomainLAM_G_DOMAIN

CNTNAP3B GAS6 CNTNAP3

1.85e-03381203PS50025
DomainInsulin

INS INS-IGF2

2.17e-03111202IPR004825
DomainInsulin-like

INS INS-IGF2

2.17e-03111202IPR016179
DomainCRAL_TRIO_N

SEC14L3 SEC14L2

2.17e-03111202PF03765
DomainIlGF

INS INS-IGF2

2.17e-03111202SM00078
DomainEGF_CA

GAS6 JAG1 LTBP2 NOTCH3

2.29e-03861204PF07645
DomainNucleotide-diphossugar_trans

B4GALNT4 A3GALT2 MGAT1 UAP1L1

2.49e-03881204IPR029044
DomainFerric_reduct

DUOX2 STEAP2

2.59e-03121202PF01794
DomainCRAL-bd_toc_tran

SEC14L3 SEC14L2

2.59e-03121202IPR001071
DomainFe3_Rdtase_TM_dom

DUOX2 STEAP2

2.59e-03121202IPR013130
DomainCRAL_TRIO_N

SEC14L3 SEC14L2

2.59e-03121202SM01100
DomainEGF_Ca-bd_CS

GAS6 JAG1 LTBP2 NOTCH3

3.55e-03971204IPR018097
DomainEGF_CA

GAS6 JAG1 LTBP2 NOTCH3

3.82e-03991204PS01187
DomainASX_HYDROXYL

GAS6 JAG1 LTBP2 NOTCH3

3.95e-031001204PS00010
DomainCRAL/TRIO_N_dom

SEC14L3 SEC14L2

4.07e-03151202IPR011074
DomainEMP24_GP25L

SEC14L3 SEC14L2

4.07e-03151202PF01105
DomainEGF

CNTNAP3B GAS6 CNTNAP3 JAG1 LTBP2 NOTCH3

4.13e-032351206SM00181
DomainATPase_P-typ_TM_dom

ATP2A2 ATP2A3

4.63e-03161202IPR023298
Domain-

ATP2A2 ATP2A3

4.63e-031612021.20.1110.10
DomainEGF-type_Asp/Asn_hydroxyl_site

GAS6 JAG1 LTBP2 NOTCH3

4.87e-031061204IPR000152
DomainATPase_P-typ_cation-transptr_C

ATP2A2 ATP2A3

5.23e-03171202IPR006068
DomainCation_ATPase_C

ATP2A2 ATP2A3

5.23e-03171202PF00689
DomainCation_ATPase_N

ATP2A2 ATP2A3

5.86e-03181202PF00690
DomainCation_ATPase_N

ATP2A2 ATP2A3

5.86e-03181202SM00831
Pubmed

Evaluation of Notch3 Deficiency in Diabetes-Induced Pericyte Loss in the Retina.

INS INS-IGF2 NOTCH3

4.53e-083125330347392
Pubmed

SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.

INS ATP2A2 INS-IGF2

4.53e-083125337537395
Pubmed

Klotho attenuates renal hypertrophy and glomerular injury in Ins2Akita diabetic mice.

INS KL INS-IGF2

4.53e-083125326586006
Pubmed

Regulation of dendritic cell function by insulin/IGF-1/PI3K/Akt signaling through klotho expression.

INS KL INS-IGF2

1.81e-074125327808000
Pubmed

Antiaging gene Klotho enhances glucose-induced insulin secretion by up-regulating plasma membrane levels of TRPV2 in MIN6 β-cells.

INS KL INS-IGF2

1.81e-074125322597535
Pubmed

Notch gene expression during pancreatic organogenesis.

INS JAG1 INS-IGF2 NOTCH3

2.80e-0716125410842072
Pubmed

Integration of ER protein quality control mechanisms defines β cell function and ER architecture.

ATG7 INS INS-IGF2

4.51e-075125336346671
Pubmed

The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.

MPO DUOX2 LPO

4.51e-075125327048452
Pubmed

Sel1L-Hrd1 ER-associated degradation maintains β cell identity via TGF-β signaling.

ATG7 INS INS-IGF2

8.99e-076125332182217
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

INS JAG1 INS-IGF2 NOTCH3

9.08e-0721125414702043
Pubmed

A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene.

INS HLA-DRB1 INS-IGF2

1.57e-067125317632545
Pubmed

Cdc42-mediated tubulogenesis controls cell specification.

INS JAG1 INS-IGF2 NOTCH3

3.05e-0628125419914171
Pubmed

Role of nutrient-driven O-GlcNAc-post-translational modification in pancreatic exocrine and endocrine islet development.

OGT INS INS-IGF2

5.34e-0610125332165492
Pubmed

SGLT1/2 inhibition improves glycemic control and multi-organ protection in type 1 diabetes.

INS INS-IGF2

1.28e-052125237520739
Pubmed

Neuritic dystrophy and neuronopathy in Akita (Ins2(Akita)) diabetic mouse sympathetic ganglia.

INS INS-IGF2

1.28e-052125219111542
Pubmed

Growth factors and medium hyperglycemia induce Sox9+ ductal cell differentiation into β cells in mice with reversal of diabetes.

INS INS-IGF2

1.28e-052125226733677
Pubmed

Progressive Thinning of Retinal Nerve Fiber Layer/Ganglion Cell Layer (RNFL/GCL) as Biomarker and Pharmacological Target of Diabetic Retinopathy.

INS INS-IGF2

1.28e-052125237628852
Pubmed

Decreased Satellite Cell Number and Function in Humans and Mice With Type 1 Diabetes Is the Result of Altered Notch Signaling.

INS INS-IGF2

1.28e-052125227335233
Pubmed

Expression of preproinsulin-2 gene shapes the immune response to preproinsulin in normal mice.

INS INS-IGF2

1.28e-052125214688305
Pubmed

Bioinformatics Analysis of Weighted Genes in Diabetic Retinopathy.

INS INS-IGF2

1.28e-052125230480744
Pubmed

The implications of hyperoxia, type 1 diabetes and sex on cardiovascular physiology in mice.

INS INS-IGF2

1.28e-052125234845324
Pubmed

Genetic control of insulin receptors.

INS INS-IGF2

1.28e-05212527031649
Pubmed

Thymic expression of mutated B16:A preproinsulin messenger RNA does not reverse acceleration of NOD diabetes associated with insulin 2 (thymic expressed insulin) knockout.

INS INS-IGF2

1.28e-052125216289958
Pubmed

Insulin rescues impaired spermatogenesis via the hypothalamic-pituitary-gonadal axis in Akita diabetic mice and restores male fertility.

INS INS-IGF2

1.28e-052125222522616
Pubmed

Identification of novel targets of diabetic nephropathy and PEDF peptide treatment using RNA-seq.

INS INS-IGF2

1.28e-052125227855634
Pubmed

Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease.

INS INS-IGF2

1.28e-052125226203118
Pubmed

Maternal Chromium Restriction Leads to Glucose Metabolism Imbalance in Mice Offspring through Insulin Signaling and Wnt Signaling Pathways.

INS INS-IGF2

1.28e-052125227782077
Pubmed

Identification of novel diabetes impaired miRNA-transcription factor co-regulatory networks in bone marrow-derived Lin-/VEGF-R2+ endothelial progenitor cells.

INS INS-IGF2

1.28e-052125229995913
Pubmed

Maternal diabetes adversely affects preovulatory oocyte maturation, development, and granulosa cell apoptosis.

INS INS-IGF2

1.28e-052125215718275
Pubmed

Insulin-Deficient Mouse β-Cells Do Not Fully Mature but Can Be Remedied Through Insulin Replacement by Islet Transplantation.

INS INS-IGF2

1.28e-052125229029025
Pubmed

Comparison of ADAM19 and CUEDC2 expression in EHCC and their clinicopathological significance.

ADAM19 CUEDC2

1.28e-052125232960074
Pubmed

Mutant INS-gene induced diabetes of youth: proinsulin cysteine residues impose dominant-negative inhibition on wild-type proinsulin transport.

INS INS-IGF2

1.28e-052125220948967
Pubmed

Prevalence and Clinical Characteristics of PDX1 Variant Induced Diabetes in Chinese Early-Onset Type 2 Diabetes.

INS INS-IGF2

1.28e-052125237279936
Pubmed

An imprinted GFP insertion reveals long-range epigenetic regulation in embryonic lineages.

INS INS-IGF2

1.28e-052125219778534
Pubmed

Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.

INS INS-IGF2

1.28e-052125226696124
Pubmed

Jagged-1 and Notch3 juxtacrine loop regulates ovarian tumor growth and adhesion.

JAG1 NOTCH3

1.28e-052125218632624
Pubmed

Compensatory hyperinsulinemia in high-fat diet-induced obese mice is associated with enhanced insulin translation in islets.

INS INS-IGF2

1.28e-052125225686499
Pubmed

Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring.

INS INS-IGF2

1.28e-052125223209676
Pubmed

Hyper-Variability in Circulating Insulin, High Fat Feeding Outcomes, and Effects of Reducing Ins2 Dosage in Male Ins1-Null Mice in a Specific Pathogen-Free Facility.

INS INS-IGF2

1.28e-052125227055260
Pubmed

Type 1 diabetic cardiomyopathy in the Akita (Ins2WT/C96Y) mouse model is characterized by lipotoxicity and diastolic dysfunction with preserved systolic function.

INS INS-IGF2

1.28e-052125219801494
Pubmed

Increasing hepatic glycogen moderates the diabetic phenotype in insulin-deficient Akita mice.

INS INS-IGF2

1.28e-052125233667544
Pubmed

Tissue- and developmental stage-specific imprinting of the mouse proinsulin gene, Ins2.

INS INS-IGF2

1.28e-05212527729600
Pubmed

Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes.

INS INS-IGF2

1.28e-052125222015457
Pubmed

Impact of genetic background on nephropathy in diabetic mice.

INS INS-IGF2

1.28e-052125216118394
Pubmed

High glucose and diabetes modulate cellular proteasome function: Implications in the pathogenesis of diabetes complications.

INS INS-IGF2

1.28e-052125223391566
Pubmed

A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy.

INS INS-IGF2

1.28e-052125217151334
Pubmed

Dynamic Ins2 Gene Activity Defines β-Cell Maturity States.

INS INS-IGF2

1.28e-052125236170671
Pubmed

Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages.

INS INS-IGF2

1.28e-052125223894189
Pubmed

Metabolic effects of short-term caloric restriction in mice with reduced insulin gene dosage.

INS INS-IGF2

1.28e-052125229439088
Pubmed

Hyperglycemia and xerostomia are key determinants of tooth decay in type 1 diabetic mice.

INS INS-IGF2

1.28e-052125222449801
Pubmed

Insulin2 gene (Ins2) transcription by NOD bone marrow-derived cells does not influence autoimmune diabetes development in NOD-Ins2 knockout mice.

INS INS-IGF2

1.28e-052125219874548
Pubmed

Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes.

INS INS-IGF2

1.28e-052125216936198
Pubmed

Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes.

INS INS-IGF2

1.28e-052125230019207
Pubmed

Imprinting at the mouse Ins2 locus: evidence for cis- and trans-allelic interactions.

INS INS-IGF2

1.28e-05212529465295
Pubmed

The selective recruitment of mRNA to the ER and an increase in initiation are important for glucose-stimulated proinsulin synthesis in pancreatic beta-cells.

INS INS-IGF2

1.28e-052125215972000
Pubmed

Cardiac transcriptome profiling of diabetic Akita mice using microarray and next generation sequencing.

INS INS-IGF2

1.28e-052125228837672
Pubmed

Inducing Specific Immune Tolerance to Prevent Type 1 Diabetes in NOD Mice.

INS INS-IGF2

1.28e-052125226784909
Pubmed

Novel splice variant of mouse insulin2 mRNA: implications for insulin expression.

INS INS-IGF2

1.28e-052125220153322
Pubmed

Transgenic Expression of miR-133a in the Diabetic Akita Heart Prevents Cardiac Remodeling and Cardiomyopathy.

INS INS-IGF2

1.28e-052125231069235
Pubmed

High fat diet induces brain insulin resistance and cognitive impairment in mice.

INS INS-IGF2

1.28e-052125227771511
Pubmed

Activation of endothelial NAD(P)H oxidase accelerates early glomerular injury in diabetic mice.

INS INS-IGF2

1.28e-052125226552047
Pubmed

Predisposition to Proinsulin Misfolding as a Genetic Risk to Diet-Induced Diabetes.

INS INS-IGF2

1.28e-052125234462258
Pubmed

Prevention of diabetic nephropathy in Ins2(+/)⁻(AkitaJ) mice by the mitochondria-targeted therapy MitoQ.

INS INS-IGF2

1.28e-052125220825366
Pubmed

Register shifting of an insulin peptide-MHC complex allows diabetogenic T cells to escape thymic deletion.

INS INS-IGF2

1.28e-052125222065673
Pubmed

Increased superoxide contributes to enhancement of vascular contraction in Ins2(Akita) diabetic mice, an autosomal dominant mutant model.

INS INS-IGF2

1.28e-052125218788099
Pubmed

Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice.

INS INS-IGF2

1.28e-052125215889095
Pubmed

Interaction of glucagon-like peptide-I (7-37) and somatostatin-14 on signal transduction and proinsulin gene expression in beta TC-1 cells.

INS INS-IGF2

1.28e-05212527911222
Pubmed

Complications of IgA nephropathy in a non-insulin-dependent diabetes model, the Akita mouse.

INS INS-IGF2

1.28e-052125212630555
Pubmed

Retinal blood flow abnormalities following six months of hyperglycemia in the Ins2(Akita) mouse.

INS INS-IGF2

1.28e-052125222440813
Pubmed

Dual inhibition of SGLT2 and DPP-4 promotes natriuresis and improves glomerular hemodynamic abnormalities in KK/Ta-Ins2Akita mice with progressive diabetic kidney disease.

INS INS-IGF2

1.28e-052125236265286
Pubmed

β-Cell Cre Expression and Reduced Ins1 Gene Dosage Protect Mice From Type 1 Diabetes.

INS INS-IGF2

1.28e-052125236048448
Pubmed

Epistasis Between HLA-DRB1*16:02:01 and SLC16A11 T-C-G-T-T Reduces Odds for Type 2 Diabetes in Southwest American Indians.

HLA-DRB1 SLC16A11

1.28e-052125238530923
Pubmed

Myeloperoxidase/HLA Class II Complexes Recognized by Autoantibodies in Microscopic Polyangiitis.

MPO HLA-DRB1

1.28e-052125228575531
Pubmed

Proinsulin atypical maturation and disposal induces extensive defects in mouse Ins2+/Akita β-cells.

INS INS-IGF2

1.28e-052125222509386
Pubmed

New mouse model to study islet transplantation in insulin-dependent diabetes mellitus.

INS INS-IGF2

1.28e-052125211981430
Pubmed

β-Cell pre-mir-21 induces dysfunction and loss of cellular identity by targeting transforming growth factor beta 2 (Tgfb2) and Smad family member 2 (Smad2) mRNAs.

INS INS-IGF2

1.28e-052125234246804
Pubmed

Both spontaneous Ins2(+/-) and streptozotocin-induced type I diabetes cause bone loss in young mice.

INS INS-IGF2

1.28e-052125222886636
Pubmed

Nonobese, insulin-deficient Ins2Akita mice develop type 2 diabetes phenotypes including insulin resistance and cardiac remodeling.

INS INS-IGF2

1.28e-052125217911348
Pubmed

Genetic analysis of a new mouse model for non-insulin-dependent diabetes.

INS INS-IGF2

1.28e-052125211414755
Pubmed

Estrogens Promote Misfolded Proinsulin Degradation to Protect Insulin Production and Delay Diabetes.

INS INS-IGF2

1.28e-052125229972779
Pubmed

NOTCH3 expression is induced in mural cells through an autoregulatory loop that requires endothelial-expressed JAGGED1.

JAG1 NOTCH3

1.28e-052125219150886
Pubmed

Chronic restraint stress induces hippocampal memory deficits by impairing insulin signaling.

INS INS-IGF2

1.28e-052125229970188
Pubmed

Diabetic Stroke Severity: Epigenetic Remodeling and Neuronal, Glial, and Vascular Dysfunction.

INS INS-IGF2

1.28e-052125226470785
Pubmed

Quantification of insulin gene expression during development of pancreatic islet cells.

INS INS-IGF2

1.28e-052125219812524
Pubmed

Tuberculosis susceptibility of diabetic mice.

INS INS-IGF2

1.28e-052125217585110
Pubmed

A new model of insulin-deficient diabetes: male NOD mice with a single copy of Ins1 and no Ins2.

INS INS-IGF2

1.28e-052125216612590
Pubmed

Inhibition of nitric oxide production reverses diabetes-induced Kupffer cell activation and Klebsiella pneumonia liver translocation.

INS INS-IGF2

1.28e-052125228493939
Pubmed

Dealing with employment issues.

INS INS-IGF2

1.28e-052125220043456
Pubmed

Loss of insulin signaling may contribute to atrial fibrillation and atrial electrical remodeling in type 1 diabetes.

INS INS-IGF2

1.28e-052125232198206
Pubmed

RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon.

INS INS-IGF2

1.28e-05212522427930
Pubmed

Differential Impact of Chronic Hyperglycemia on Humoral Versus Cellular Primary Alloimmunity.

INS INS-IGF2

1.28e-052125228069641
Pubmed

Macrophages and neutrophils are necessary for ER stress-induced β cell loss.

INS INS-IGF2

1.28e-052125236001973
Pubmed

Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy.

INS INS-IGF2

1.28e-052125229211719
Pubmed

The brain response to peripheral insulin declines with age: a contribution of the blood-brain barrier?

INS INS-IGF2

1.28e-052125225965336
Pubmed

Determination of insulin in a single islet of Langerhans by high-performance liquid chromatography with fluorescence detection.

INS INS-IGF2

1.28e-052125212038757
Pubmed

Diabetic modifier QTL, Dbm4, affecting elevated fasting blood glucose concentrations in congenic mice.

INS INS-IGF2

1.28e-052125223412636
Pubmed

A protein interaction mechanism for suppressing the mechanosensitive Piezo channels.

PIEZO1 ATP2A2

1.28e-052125229176668
Pubmed

Caspr3-Deficient Mice Exhibit Low Motor Learning during the Early Phase of the Accelerated Rotarod Task.

CNTNAP3B CNTNAP3

1.28e-052125226807827
Pubmed

The Ins2Akita mouse as a model of early retinal complications in diabetes.

INS INS-IGF2

1.28e-052125215914643
Pubmed

Adaptive evolution of the insulin two-gene system in mouse.

INS INS-IGF2

1.28e-052125218245324
Cytoband15q15.3

DUOX2 STRC STRCP1

4.34e-0525125315q15.3
CytobandEnsembl 112 genes in cytogenetic band chr15q15

SPINT1 IVD PAK6-AS1 STRC STRCP1

5.41e-051471255chr15q15
Cytoband17q23.1

MPO LPO

8.61e-0416125217q23.1
Cytoband1p13

RBM15 IGSF3

9.74e-041712521p13
Cytoband2q35

GPBAR1 RETREG2 SPEG

1.34e-037912532q35
Cytoband17p13.3

MYBBP1A PRPF8 ATP2A3

1.83e-0388125317p13.3
CytobandEnsembl 112 genes in cytogenetic band chr17p13

MYBBP1A PRPF8 SLC16A11 ATP2A3 GP1BA

2.65e-033461255chr17p13
GeneFamilySEC14 family|PRELI domain containing

SEC14L3 SEC14L2

2.87e-0468021063
GeneFamilyATPases Ca2+ transporting

ATP2A2 ATP2A3

6.82e-0498021209
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 DCHS1 C9orf50 GRIN3A RASGRP2 NPAS1

1.17e-071361257e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 KCNK12 IGLL5 NLRC5 ATP2A3 S1PR4 RASGRP2

8.12e-07181125751e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellwk_08-11-Hematologic_Lymphocytic-B-Immature_B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 KCNK12 IGLL5 RASAL3 ATP2A3 S1PR4 RASGRP2

9.06e-071841257e6669a1b7ea7e4f8e094add5117689470019d85d
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 IGLL5 RASAL3 NLRC5 ATP2A3 S1PR4 RASGRP2

9.40e-0718512578fc357ee041bfd588986730a52ea2021b5f88941
ToppCellCOVID-19_Severe-cDC|COVID-19_Severe / disease group, cell group and cell class

LAYN SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.34e-0619512576419090b19de7b5d5140eaecf231860273da2c0d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPBWR1 CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

1.46e-061251256d05556ea185c15815a4f8643f1c01185badbeece
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPBWR1 CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

1.75e-061291256f83187c0bb06528127b8d2d56674ab1946846951
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A IGSF3 RASGRP2 NPAS1

3.32e-06144125671107275767a0728541a3695715c44874b3e5efc
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAYN CNTNAP3 PLPP2 GRIN3A RASGRP2 NPAS1

4.37e-061511256090b067873740c282865e2d02cf47d5cb3dd7607
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 ERN2 GRIN3A RASGRP2 NPAS1

5.46e-061571256741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCellClub_cells-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

THSD7A CYP2J2 ACSS1 ERN2 PLPP2 NOTCH3

6.09e-061601256b261a3a49c850d92bc9e04fc3527c752dfe37a1a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 DCHS1 GRIN3A RASGRP2 NPAS1

6.31e-061611256dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THSD7A CNTNAP3 STEAP2 SYDE1 DUSP23 C9orf50

7.52e-061661256b4241f8d2a0aa910dbb0d0d5d3631a9b73453fe9
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

CNTNAP3 CCNF SELENOO DCHS1 LTBP2 IGSF3

9.21e-061721256df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 ARHGEF39 JAG1 SLC16A11 ATP2A3 NOTCH3

9.52e-0617312562415b6ff49f334da570577d4e93484d024a3dbd5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 ARHGEF39 JAG1 SLC16A11 ATP2A3 NOTCH3

9.52e-0617312562acd0693a2dfe04e3c1b2125ea63efe92d13150b
ToppCell3'-GW_trimst-1-SmallIntestine-Hematopoietic-B_cells-Pre-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HLA-DRB1 KCNK12 IGLL5 RASAL3 NLRC5 S1PR4

1.08e-051771256ecd26d086c1aff3be442fcb055611a563ca034ef
ToppCellASK440-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

CNTNAP3 CCNF SELENOO DCHS1 LTBP2 IGSF3

1.12e-05178125686f1741636ed3e85bb4a65f84949b718fc38c290
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPBAR1 SPEG RGS9 SLC16A11 NOTCH3 RASGRP2

1.16e-051791256d76a05f1fee7f2f7b7b7994d3622e96f02b49432
ToppCellfacs-Heart-RA-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPBAR1 SPEG RGS9 SLC16A11 NOTCH3 RASGRP2

1.16e-0517912566be47c877250968a916c711ba0787eb7b4c5443d
ToppCell11.5-Airway-Immune-Hematopoietic,_B_Cells|Airway / Age, Tissue, Lineage and Cell class

HLA-DRB1 IGLL5 NLRC5 ATP2A3 S1PR4 RASGRP2

1.23e-051811256727344d7b2953568b7b3463398c7d56878cf2c2b
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAYN SPINT1 MBOAT7 GAS6 DUSP23 PRCP

1.53e-0518812568431991e68b8e9c5eb72212460f6da679ea3b85a
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_8|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LAYN SPINT1 MBOAT7 GAS6 DUSP23 PRCP

1.53e-051881256d8f10b3ad11bc99a63f44560e39791085256e5c8
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG KL SLC16A11 ATP2A3 NOTCH3 RASGRP2

1.67e-05191125696ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCellwk_15-18-Hematologic_Lymphocytic-B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 IGLL5 NLRC5 ATP2A3 S1PR4 RASGRP2

1.72e-05192125647fec69fccbabf9db95e5a1246c67bddf89bc76b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ADAM19 SPEG LEFTY2 JAG1 LTBP2 NOTCH3

1.77e-051931256000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.82e-0519412566af2971d83f5ad6aed16d0ceb8bfc52f3947bc10
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG JAG1 SLC16A11 ATP2A3 NOTCH3 RASGRP2

1.82e-0519412563bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.82e-0519412565c60670ec24470225fabaa6071fdb4ef6e579840
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD CNTNAP3B ZBTB7C HLA-DRB1 ARAP3 PRCP

1.82e-051941256b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD CNTNAP3B HLA-DRB1 GAS6 ARAP3 PRCP

1.82e-051941256ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ADAM19 SPEG LEFTY2 JAG1 LTBP2 NOTCH3

1.82e-05194125667f5e2f05a8de2213ab80d5ea16fdee121684633
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPEG JAG1 SLC16A11 ATP2A3 NOTCH3 RASGRP2

1.82e-051941256fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCellEpithelial_cells-Club_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ZBTB7C STEAP2 ERN2 PLPP2 ATP2A3 NOTCH3

1.88e-051951256b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.93e-051961256e1f763fa9c11bf5f4d80e79f70f9485724ac23fe
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT1 ARHGEF5 PIEZO1 GAS6 PLPP2 IGSF3

1.93e-05196125622fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCellControl-Myeloid-cDC|Control / Disease group, lineage and cell class

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.93e-05196125685d92bc226cc28384c30991cc4ebb02ec2e3ec99
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.93e-051961256553c22c7d48f3b4f6f2b2f10d6e668c5ebb09e8c
ToppCellCOVID-19_Moderate-cDC|World / disease group, cell group and cell class

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.93e-05196125692a236adf386f05d020b1954bbdc5bd32346cbf0
ToppCellPBMC-Control-Myeloid-cDC|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.93e-051961256d376168e15ec1cf618723259966c76be3698b9b0
ToppCellPBMC-Control-Myeloid-cDC-cDC|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAYN SPINT1 HLA-DRB1 GAS6 DUSP23 PRCP

1.93e-0519612564a9095ba3f6709f88f32bf09184553f4bd211f43
ToppCellPBMC-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.99e-0519712569162ede5572326c00ede0769fe7f4e0dd14d2340
ToppCellPBMC-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.99e-051971256021c9c48375259b808e1f36a029c4fe6971c00eb
ToppCellPBMC-Mild-Myeloid-cDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.99e-05197125618df0e447bcea2a405a357563f87bacc57466227
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT1 ARHGEF5 PLPP2 JAG1 LTBP2 IGSF3

1.99e-051971256b1c6a15bf6c0645952a7247182dc71baf4736869
ToppCellPBMC-Mild-Myeloid-cDC-cDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.99e-0519712560460b6907743a354792b5bc40bff01aac7c41684
ToppCellCOVID-19_Mild-Myeloid-cDC|COVID-19_Mild / Disease group, lineage and cell class

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

1.99e-0519712562901904b8a791fac2668fd737eff7e7144378db4
ToppCellmoderate-Epithelial-Secretory|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SPINT1 CYP2J2 DUOX2 STEAP2 ERN2 PLPP2

2.04e-0519812567d96d7105a849c7280ce87bd76ce130ac47384fd
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3B ADAM19 LAYN THSD7A CNTNAP3 ARAP3

2.04e-051981256b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CNTNAP3B ADAM19 LAYN THSD7A CNTNAP3 ARAP3

2.04e-051981256fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellCOVID-19_Severe-cDC|World / disease group, cell group and cell class

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

2.04e-051981256c452334249f047265ae89dcabe7de446d968cae6
ToppCellproximal-Epithelial-Differentiating_Basal-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAYN SPINT1 CYP2J2 ERN2 DMRT3 PLPP2

2.10e-051991256c607346f60e5997e757e5a31cab412ab3734377b
ToppCellBiopsy_IPF-Epithelial-SCGB3A2+_SCGB1A1+|Biopsy_IPF / Sample group, Lineage and Cell type

SPINT1 CYP2J2 ERN2 TRAF4 PLPP2 NOTCH3

2.10e-051991256c6150f5fe2ce4466149a4d553acb907034a72efb
ToppCell(02)_MMP9/10+|World / shred by cell type by condition

ADAM19 GAS6 ARHGEF40 JAG1 LTBP2 INS-IGF2

2.10e-0519912563f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCellproximal-3-Epithelial-Differentiating_Basal|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAYN SPINT1 CYP2J2 ERN2 DMRT3 PLPP2

2.10e-05199125612e07084fc2d5d4c418df564ccc0e132b056e549
ToppCellproximal-Epithelial-Differentiating_Basal|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAYN SPINT1 CYP2J2 ERN2 DMRT3 PLPP2

2.10e-05199125696a89a2578fad9a99c52d2cf9e26e06516a96568
ToppCellCOVID-19-COVID-19_Mild-Myeloid-cDC|COVID-19_Mild / Disease, condition lineage and cell class

SPINT1 MBOAT7 HLA-DRB1 GAS6 DUSP23 PRCP

2.16e-052001256b8f52e65813d331c49cdd5f354fdfec6fc8c339e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THSD7A CNTNAP3 KL GRIN3A RASGRP2

2.64e-051241255298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Igfbp6_Car10|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THSD7A LEFTY2 GRIN3A IGSF3 NPAS1

2.85e-05126125561e599678680e5aa86291c2b347b2995014591ea
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

3.19e-0512912556bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

NPBWR1 CNTNAP3 RGS9 GRIN3A NPAS1

3.44e-0513112553cb4b272e28ee9bad6d874f64a7aae18352a6cfb
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAYN CNTNAP3 GRIN3A RASGRP2 NPAS1

3.83e-051341255657ad905b40ec3f82acdef824431b8276d291ef7
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_E|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PKDREJ GPR62 TP53I13 LTBP2 NOTCH3

3.97e-05135125535928195cf34f055b353562c96f451aef2344d64
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

THSD7A KL DUSP23 MZF1 LRIT1

4.26e-051371255ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

THSD7A KL DUSP23 MZF1 LRIT1

4.26e-05137125547859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellTCGA-Thryoid|World / Sample_Type by Project: Shred V9

DUOX2 ST6GAL2 DMRT3 PAK6-AS1 FSCN2

4.41e-0513812558cbae2ec9a51712bed5b4e5f9f834ecccb6b7a47
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAYN CNTNAP3 GRIN3A RASGRP2 NPAS1

4.88e-051411255ad9a25569c142fb68ded34aeba0cd9be8124ce56
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

5.22e-05143125524fd24846fbef049af669a57d42fcc18928d2b27
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RETREG2 MARCHF6 KL PRCP TMEM223

5.58e-05145125547a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

5.95e-05147125550e86860a94be103092c40e39a172eac92372f0d
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-valve_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 DMRT3 ART1 C9orf50 SBK2

7.19e-0515312551440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

7.42e-051541255a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MPO LAYN CUL9 GAL3ST4 SYDE1

7.42e-051541255b16f3139ce50e70a6a2377b1da7d7877b4000ea1
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 GRIN3A IGSF3 RASGRP2 NPAS1

7.65e-0515512555c7b68b59244525e3714806c205a57a2daebf423
ToppCell367C-Lymphocytic-CD4_T-cell-Treg_cell_1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

LAYN CUL9 LPO ANTKMT IGSF3

8.63e-051591255ae53ab7a1339007d0b245c6c291ac61e5ff5b682
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

8.88e-0516012550bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THSD7A STEAP2 DCHS1 GRIN3A RASGRP2

9.15e-051611255bf70be1de418615b5442ec684552551edaf1f072
ToppCelldroplet-Heart-4Chambers|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INS GAS6 ART1 ATP2A2 IGSF3

9.42e-0516212555625ec6dae204d5537883f05ea546970628d10bb
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HLA-DRB1 GAS6 GAL3ST4 B3GNT8 KL

9.70e-0516312554b8abbad4df040c895e3afb240759ebbc66b4d0e
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPEG ST6GAL2 LTBP2 STRC NOTCH3

9.70e-05163125551dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCell5'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL11A2 CYP2J2 DMRT3 PLPP2 NOTCH3

9.98e-0516412558d1d0424943d3e98c8b6399dbf702e0035d0db7b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

THSD7A CNTNAP3 STEAP2 SYDE1 C9orf50

9.98e-051641255f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPIPB2 ST6GAL2 TSPAN10 STRC GP1BA

1.09e-0416712558b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells-Pro-B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK12 RASAL3 NLRC5 S1PR4 RASGRP2

1.15e-0416912557fd13b6e6041032697d36dd215f6b943d4675cf2
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-B_cells|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNK12 RASAL3 NLRC5 S1PR4 RASGRP2

1.18e-041701255e319ab46842d028898c09d6d8f056f896edb1558
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD7A DUSP23 ARAP3 PRCP DCHS1

1.18e-0417012551a568efcff9c39b3f709b55a05d24710450a2657
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPINT1 KCNK12 ARHGEF40 ARHGEF39 FSCN2

1.18e-041701255bf589c4297ccc90e5f51e3d0fcc229548af4fcef
ToppCell3'-Parenchyma_lung-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYBBP1A SPINT1 CYP2J2 PLPP2 SLC16A11

1.18e-041701255fed8e982d2ce234c59d4016432ed8941df36df27
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THSD7A DUSP23 ARAP3 PRCP DCHS1

1.18e-04170125566d41d794790e621d72ac37af995510537103c9c
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l48|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MYBBP1A ADAM19 RASAL3 NLRC5 C9orf50

1.18e-041701255070d8683d1a5cc7d594ff0453c961a9bf982c2d0
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBM15 MBOAT7 CCNF METRN ARHGEF39

1.18e-041701255a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CNTNAP3 RGS9 GRIN3A RASGRP2 NPAS1

1.18e-0417012558ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GAS6 JAG1 NLRC5 NOTCH3 RASGRP2

1.21e-041711255285533ca2a6a411773313166bee35542f34d1a3c
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MPO SRD5A2 SEC14L3 LPO MAP3K19

1.25e-0417212556b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

TTC28 SEC14L3 SLC16A11 ATP2A3 SEC14L2

1.32e-041741255ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A DUOX2 DUSP23 PRCP JAG1

1.35e-0417512552e54961846c65b185d9bd6e305dd81205579d890
ToppCell11.5-Distal-Immune-Hematopoietic,_B_Cells|Distal / Age, Tissue, Lineage and Cell class

HLA-DRB1 IGLL5 ATP2A3 S1PR4 RASGRP2

1.35e-041751255d8ca8fbe5309dab293c335b32f1b138edfdd0b07
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

JCAD CNTNAP3B THSD7A ARAP3 DCHS1

1.35e-0417512550a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD7A DUOX2 DUSP23 PRCP JAG1

1.35e-041751255efa6a05f7417d46141b6e635f258c126b7a03aa1
ToppCellwk_08-11-Hematologic_Lymphocytic-B-Large_pre-B|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HLA-DRB1 KCNK12 IGLL5 ATP2A3 S1PR4

1.39e-04176125578417a5ac2e45e97e7b4c56c78c25879a1b58f97
DrugCefuroxime sodium salt [56238-63-2]; Down 200; 9uM; HL60; HT_HG-U133A

SPINT1 COQ6 ERN2 TRIM14 SYDE1 IVD ARAP3 METRN RASGRP2

1.27e-0619712392526_DN
Diseaseautosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)

STRC STRCP1

1.59e-0521182DOID:0110471 (implicated_via_orthology)
DiseaseBrody myopathy (implicated_via_orthology)

ATP2A2 ATP2A3

4.74e-0531182DOID:0050692 (implicated_via_orthology)
Diseaseplatelet crit

JCAD PGS1 TBRG4 RETREG2 TTC28 PIEZO1 ARHGEF40 USP38 DCHS1 SEC14L2 NOTCH3 S1PR4 GP1BA

1.16e-0495211813EFO_0007985
Diseaseleptin measurement

NPBWR1 HLA-DRB1 RGS9 RB1CC1

3.19e-04811184EFO_0005000
Diseaselymphedema, filarial elephantiasis

HLA-DRB1 ERN2

3.29e-0471182EFO_0007272, MONDO_0019297
Diseasemitochondrial DNA measurement

NPBWR1 TBRG4 HLA-DRB1 RB1CC1 LPO SELENOO S1PR4

3.62e-043281187EFO_0006312
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP3B CNTNAP3

4.37e-0481182DOID:0060308 (implicated_via_orthology)
DiseaseBMI-adjusted waist-hip ratio, adult onset asthma

LAYN SCYL1

5.60e-0491182EFO_0007788, EFO_1002011
Diseaselatent autoimmune diabetes in adults, type 2 diabetes mellitus

INS INS-IGF2

5.60e-0491182EFO_0009706, MONDO_0005148
DiseaseDiabetic Cardiomyopathies

INS ATP2A2

8.52e-04111182C0853897
DiseasePancreatic Ductal Adenocarcinoma

ADAM19 SYDE1

8.52e-04111182C1335302
Diseasequality of life during menstruation measurement, dysmenorrheic pain measurement

NPBWR1 RB1CC1

8.52e-04111182EFO_0007889, EFO_0009366
DiseaseStreptozotocin Diabetes

MPO ATP2A2 ATP2A3 S1PR4

9.45e-041081184C0038433
DiseaseDiabetes Mellitus, Experimental

MPO ATP2A2 ATP2A3 S1PR4

9.45e-041081184C0011853
DiseaseAlloxan Diabetes

MPO ATP2A2 ATP2A3 S1PR4

9.45e-041081184C0002152
Diseaserheumatoid arthritis, smoking status measurement, ACPA-positive rheumatoid arthritis

HLA-DRB1 SEC14L3

1.20e-03131182EFO_0000685, EFO_0006527, EFO_0009459
Diseaselymphocyte measurement

TTC28 HLA-DRB1 PIEZO1 NLRC5

1.27e-031171184EFO_0803546
Diseasemyelodysplastic syndrome (implicated_via_orthology)

ATG7 PRPF8

1.61e-03151182DOID:0050908 (implicated_via_orthology)
DiseaseDisorder of eye

COL11A2 RGS9 PRPF8 FSCN2 TCTN2

1.66e-032121185C0015397
DiseasePancreatitis

MPO INS HLA-DRB1

1.72e-03591183C0030305
DiseaseUrticaria

MPO HLA-DRB1

1.83e-03161182C0042109
DiseaseMoyamoya Disease

HLA-DRB1 JAG1

2.07e-03171182C0026654
Diseaseresponse to homoharringtonine, cytotoxicity measurement

DACT2 DMRT3

2.07e-03171182EFO_0006952, EFO_0006996
Diseaselupus nephritis (is_implicated_in)

MPO HLA-DRB1

2.33e-03181182DOID:0080162 (is_implicated_in)
Diseaseglucose homeostasis measurement, acute insulin response measurement

ATP2A2 ATP2A3

2.33e-03181182EFO_0006831, EFO_0006896
Diseaseanorectal malformation

GAS6 LTB4R2

2.59e-03191182MONDO_0019938
Diseasechronic kidney disease (is_marker_for)

KL GP1BA

2.87e-03201182DOID:784 (is_marker_for)
Diseaseinsular cortex volume measurement

THSD7A VPS13C

3.80e-03231182EFO_0010309
DiseaseWeight decreased

ATG7 INS

3.80e-03231182C1262477
Diseaseage of onset of asthma

ADAM19 TTC28 LTBP2

3.95e-03791183OBA_2001001

Protein segments in the cluster

PeptideGeneStartEntry
AREPAAFWGPLARDT

ACSS1

66

Q9NUB1
WASRLFAPNVLPRTG

CDRT15L2

266

A8MXV6
MFWRRLRPGAQDLAP

C9orf50

1

Q5SZB4
EARFLRFLPLAWNPR

CNTNAP3

151

Q9BZ76
QLAALPWQLLRPGDF

ARHGEF40

91

Q8TER5
RDAPPRLWCVLGAAL

ARAP3

701

Q8WWN8
GPWRLPFLGNFFLVD

CYP2J2

46

P51589
ALQPLRPRAAREPGW

ADAM19

16

Q9H013
LAGRQARTLAPPELW

ARHGEF5

111

Q12774
RSGEPLDRALVLWFP

GTPBP3

86

Q969Y2
LDRALVLWFPGPQSF

GTPBP3

91

Q969Y2
LAGRQARTLAPPELW

ARHGEF35

111

A5YM69
VAWQRFLPSGPIALL

COQ6

246

Q9Y2Z9
AAWEGPNQDLPRRLR

CUEDC2

191

Q9H467
NALQRLRPGWLAPLF

AMIGO3

71

Q86WK7
LRPGWLAPLFQLRAL

AMIGO3

76

Q86WK7
PRSPREALISGWLFF

ATP2A3

821

Q93084
GTLRPPERQALFGSW

ARHGEF39

56

Q8N4T4
AVWALLLQPGFRRVP

ANTKMT

36

Q9BQD7
APRAGPGQLFWAERF

RASAL3

341

Q86YV0
ERWFPLLGAPAGAAL

RASAL3

401

Q86YV0
GLGPWVPLAALAREF

RBM15

461

Q96T37
QALALAFALRSWRPP

TP53I13

171

Q8NBR0
LFLAPGARRWINIDG

RGS9

356

O75916
LALLALWGPDPAAAF

INS

11

P01308
QNPGAFRLAPALPAW

NSUN5

376

Q96P11
RLRRFAALGAPPWGL

NPAS1

96

Q99742
APLERISAARGWALP

LINC02906

71

E5RJ46
FLRNRLFRGLDSWPP

RB1CC1

546

Q8TDY2
ARPLDFEAGPPWRAL

DCHS1

1391

Q96JQ0
ADQGWVPLPRLLAVF

SLC16A11

301

Q8NCK7
PFRPLWALLAFALPA

GPR62

171

Q9BZJ7
PFAREWRAQSLPLAV

GLIPR1L2

6

Q4G1C9
LALPDWLDPARTRLN

RASGRP2

316

Q7LDG7
NALLLLFFWTRPAPG

MGAT1

21

P26572
WGPRERRALFLQATP

METRN

121

Q9UJH8
ALGIAWDRRLRSPPA

GPBAR1

36

Q8TDU6
NLLPSDGDFWIGLRR

LAYN

96

Q6UX15
GPRRERPDFWASLLL

LRRC75A

21

Q8NAA5
RGSRPWPRLGLQLQF

ERN2

6

Q76MJ5
FGQFLLKPVSRRPWD

JCAD

816

Q9P266
NREPFLQALGLLWFR

DUOX2

246

Q9NRD8
RADALRPRWDFPGAF

KCNK12

106

Q9HB15
ALQFPPEGWLRLSLN

PGAM5

241

Q96HS1
AAAAGPVFWRRLLGL

PGS1

6

Q32NB8
PALGAANRALARWLP

LPO

151

P22079
PTLGASNRAFVRWLP

MPO

186

P05164
GLLNPVAVPLDWARL

NOTCH3

2161

Q9UM47
WAGAPPVDVLRALRF

COL11A2

26

P13942
PWATIALRPALRALG

PRCP

16

P42785
LLRRAWPAPLFGLLF

MBOAT7

191

Q96N66
LRPGVLWFLRNLNDP

MARCHF6

446

O60337
KFLQDGLPPTWRDFR

MED27

286

Q6P2C8
RFLLLGFSDWPSLQP

OR2I1P

11

Q8NGU4
LLANLRGPALWLPRS

OR2I1P

81

Q8NGU4
GRLRPNFLAVCDPDW

PLPP2

121

O43688
ASWRLRPPLAGFVSQ

IVD

16

P26440
ARNLLWFDFGLPFPP

GAL3ST4

206

Q96RP7
ELRLPGNRLAAFPWA

LRIT1

111

Q9P2V4
GNRLAAFPWAALRDA

LRIT1

116

Q9P2V4
AFPWAALRDAPKLRL

LRIT1

121

Q9P2V4
GRPAGLFSLRVQEPW

NLRC5

1376

Q86WI3
FWRVVRFLSPPALQG

MYBBP1A

391

Q9BQG0
GARAEALWPRDALLF

GRIN3A

116

Q8TCU5
RNPKEPLISGWLFFR

ATP2A2

821

P16615
LWGRLLLQPSPQRAD

IGLL5

66

B9A064
GSPWEGRLRFQRLSP

IGSF3

1046

O75054
PGWPLRNFLVLAAHR

ATG7

241

O95352
LQRRPALAWEAPGRS

DACT2

546

Q5SW24
LWPSPGNLKLFERAA

CCNF

81

P41002
PRPAAELAAAAALRW

DMRT3

121

Q9NQL9
VLFALWAPDLRAVPL

GAS6

521

Q14393
LALSGDTRPRFLWQP

HLA-DRB1

26

P01911
RDNFTGALRPWARPE

A3GALT2

56

U3KPV4
PEALAFNWPFLGPRQ

LEFTY2

301

O00292
GRALRNPWRGFLPLT

LTBP2

11

Q14767
NPWRGFLPLTLALFV

LTBP2

16

Q14767
PRAWLLFLRGSLPTF

GP1BA

591

P07359
GLPRLLARQGAWENP

KL

646

Q9UEF7
RFLAAAWRAPDFVPR

CUL9

1486

Q8IWT3
FQPLARPWRATLAAE

C1orf127

421

Q8N9H9
LAPWLLRAAARVAPF

B3GNT8

316

Q7Z7M8
PNPDDYFLLRWLRAR

SEC14L2

31

O76054
PNPDDYFLLRWLRAR

SEC14L3

31

Q9UDX4
FRLAPAQWFLREGLL

S1PR4

111

O95977
PRDRPQPWFGLAAAA

SBK2

286

P0C263
ALGLVDPRPWQLPRF

MAP3K19

576

Q56UN5
EARFLRFLPLAWNPR

CNTNAP3B

151

Q96NU0
LALLALWGPDPAAAF

INS-IGF2

11

F8WCM5
GLCEWLRRALPPAQA

IRGQ

441

Q8WZA9
PGSKRLAFLRWEFPN

TBRG4

556

Q969Z0
PINIADFLLRQWPFG

NPBWR1

91

P48145
SVLWLLRFPAVGEPN

OGT

871

O15294
DRNRIVLPFSFAWPR

JAG1

116

P78504
RDCRFLVLPQPDGRW

FSCN2

86

O14926
AARAPPAALWGRLSL

SYDE1

256

Q6ZW31
RTWFLQPFGPDGRLK

THSD7A

1591

Q9UPZ6
LIWEVFNGPLPRAAA

SCYL1

211

Q96KG9
PLFVAFLTRQAWPLG

LTB4R2

76

Q9NPC1
PGRLAWAFRLRLLGP

PKDREJ

136

Q9NTG1
WAFRLRLLGPGAARP

PKDREJ

141

Q9NTG1
LLDLWQPRFLPDVSA

RETREG2

116

Q8NC44
AAMEPAPRWLAGLRF

SELENOO

36

Q9BVL4
APRWLAGLRFDNRAL

SELENOO

41

Q9BVL4
FSALGWRRLVPAVPL

ST6GAL2

271

Q96JF0
IENLPLRLFTLWRGP

STEAP2

201

Q8NFT2
ALLQELQRWAGPLPA

MUTYH

416

Q9UIF7
PRELRVWAPLFSQLG

STRC

991

Q7RTU9
WAARAARPLPLFLGR

B4GALNT4

496

Q76KP1
AWPQFPPALRLRALA

PAK6-AS1

121

Q8N910
GIALLWAPRPFNLRS

PRPF8

401

Q6P2Q9
LRWLQGLDLSFFPRN

SPATA4

56

Q8NEY3
PLTPEQGFWLLRLRN

TRIM69

406

Q86WT6
VPNRGPFDLRSALWR

TMEM223

81

A0PJW6
QPSLRWFRDGQLLPA

SPEG

71

Q15772
LRSVWVARNPPGFAF

SRSF3

36

P84103
RLAPAGIPAVALWLL

SPINT1

11

O43278
PRPAARWAALAALSL

SPRED3

361

Q2MJR0
FDRGVGAEPLLPWNR

XRN2

881

Q9H0D6
RFWAELAPEPRAALL

UAP1L1

21

Q3KQV9
RLPARAAWFLQELPS

SRD5A2

46

P31213
LLPRQARLFAWADPT

VPS13C

3001

Q709C8
PGAFDNLLEWPFARR

TRAF4

371

Q9BUZ4
LVFNRLWFPLVRPGA

USP38

316

Q8NB14
LWFPLVRPGALAVLS

USP38

321

Q8NB14
FGGSPWLRIIIAFPR

NPIPB2

36

A6NJ64
SLGPVPVLRFDALWQ

TRIM14

296

Q14142
PPLRRWLRANLAASG

TSPAN10

281

Q9H1Z9
WQALLTAVGFRLDPP

TTC28

1781

Q96AY4
RKPAAWRAASLLFGP

ZBTB7C

481

A1YPR0
PRELRVWAPLFSQLG

STRCP1

991

A6NGW2
AQALLPPAGIWARVL

PIEZO1

271

Q92508
SAPAALRPNWALARL

TRIM4

56

Q9C037
RLLWGDLAFIPPFIR

TCTN2

21

Q96GX1
PNFSWVLPGRLAGLA

DUSP23

6

Q9BVJ7
LLWFLVVRAFPDGPG

ART1

311

P52961
WDPGPEAARLRFRCF

MZF1

36

P28698