Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionglycerol kinase activity

GK GK2

1.49e-053452GO:0004370
GeneOntologyMolecularFunctionolfactory receptor activity

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

3.90e-04431456GO:0004984
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH12 DNAH9

7.43e-0418452GO:0008569
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

SMYD1 ASH1L

9.20e-0420452GO:0042800
GeneOntologyBiologicalProcessglycerol-3-phosphate biosynthetic process

GK GK2

1.39e-053452GO:0046167
GeneOntologyBiologicalProcessglycerol catabolic process

GK GK2

6.94e-056452GO:0019563
GeneOntologyBiologicalProcessalditol catabolic process

GK GK2

9.71e-057452GO:0019405
GeneOntologyBiologicalProcessglycerol-3-phosphate metabolic process

GK GK2

2.07e-0410452GO:0006072
GeneOntologyBiologicalProcessalditol phosphate metabolic process

GK GK2

3.03e-0412452GO:0052646
GeneOntologyBiologicalProcesspolyol catabolic process

GK GK2

3.03e-0412452GO:0046174
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception of smell

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

3.33e-04432456GO:0050911
GeneOntologyCellularComponent9+2 motile cilium

ADGB GK2 DNAH12 ACE DNAH9

1.55e-04238455GO:0097729
GeneOntologyCellularComponentsperm midpiece

ADGB GK2 ACE

3.54e-0464453GO:0097225
GeneOntologyCellularComponentmotile cilium

ADGB GK2 DNAH12 ACE DNAH9

9.61e-04355455GO:0031514
GeneOntologyCellularComponentaxonemal dynein complex

DNAH12 DNAH9

1.32e-0325452GO:0005858
MousePhenodecreased sperm mitochondrial sheath size

GK GK2

8.06e-056332MP:0014464
MousePhenoabnormal sperm mitochondrial sheath size

GK GK2

8.06e-056332MP:0014462
DomainCarb_kinase_FGGY_CS

GK GK2

1.70e-053452IPR018483
DomainGlycerol_kin

GK GK2

3.40e-054452IPR005999
DomainFGGY_KINASES_2

GK GK2

5.65e-055452PS00445
DomainFGGY_KINASES_1

GK GK2

5.65e-055452PS00933
DomainCarb_kinase_FGGY_C

GK GK2

5.65e-055452IPR018485
DomainFGGY_C

GK GK2

8.46e-056452PF02782
DomainCarb_kinase_FGGY_N

GK GK2

8.46e-056452IPR018484
DomainCarb_kinase_FGGY

GK GK2

1.18e-047452IPR000577
DomainFGGY_N

GK GK2

1.18e-047452PF00370
DomainOlfact_rcpt

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

3.40e-04393456IPR000725
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH9

5.07e-0414452IPR011704
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH9

5.07e-0414452IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH9

5.07e-0414452IPR013602
DomainDHC_N2

DNAH12 DNAH9

5.07e-0414452PF08393
DomainAAA_8

DNAH12 DNAH9

5.07e-0414452PF12780
DomainAAA_5

DNAH12 DNAH9

5.07e-0414452PF07728
DomainDHC_fam

DNAH12 DNAH9

5.84e-0415452IPR026983
DomainDynein_heavy_dom

DNAH12 DNAH9

5.84e-0415452IPR004273
DomainDynein_heavy

DNAH12 DNAH9

5.84e-0415452PF03028
DomainBTB

KLHL29 ZBTB48 BACH1

3.86e-03131453PF00651
DomainSET

SMYD1 ASH1L

4.38e-0341452PF00856
DomainGPCR_Rhodpsn_7TM

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

5.16e-03670456IPR017452
Domain7tm_1

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

5.42e-03677456PF00001
DomainSET

SMYD1 ASH1L

5.49e-0346452SM00317
DomainG_PROTEIN_RECEP_F1_1

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

5.74e-03685456PS00237
DomainG_PROTEIN_RECEP_F1_2

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

5.98e-03691456PS50262
DomainGPCR_Rhodpsn

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

6.02e-03692456IPR000276
DomainSET_dom

SMYD1 ASH1L

6.46e-0350452IPR001214
DomainSET

SMYD1 ASH1L

6.46e-0350452PS50280
DomainBTB

KLHL29 ZBTB48 BACH1

6.73e-03160453PS50097
DomainBTB

KLHL29 ZBTB48 BACH1

9.28e-03180453SM00225
DomainBTB/POZ_dom

KLHL29 ZBTB48 BACH1

1.00e-02185453IPR000210
DomainSKP1/BTB/POZ

KLHL29 ZBTB48 BACH1

1.06e-02189453IPR011333
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

2.50e-04389336M14091
PathwayREACTOME_TRIGLYCERIDE_BIOSYNTHESIS

GK GK2

3.46e-0412332MM15447
PathwayREACTOME_TRIGLYCERIDE_BIOSYNTHESIS

GK GK2

4.75e-0414332M619
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

OR8G5 OR7A5 OR8G2P OR8G1

8.90e-04186334MM15994
PathwayREACTOME_TRIGLYCERIDE_METABOLISM

GK GK2

1.30e-0323332MM15575
PathwayREACTOME_RHOBTB1_GTPASE_CYCLE

DBN1 RNF20

1.30e-0323332M41817
PathwayWP_TRIACYLGLYCERIDE_SYNTHESIS

GK GK2

1.30e-0323332MM15890
PathwayWP_TRIACYLGLYCERIDE_SYNTHESIS

GK GK2

1.42e-0324332M39692
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH12 DNAH9

1.80e-0327332M47755
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR8G5 OR52A5 OR7A5 OR52A1 OR8G1

2.65e-03417335M4072
PathwayWP_FATTY_ACID_BETAOXIDATION

GK GK2

2.84e-0334332M39596
PathwayWP_FATTY_ACID_BETAOXIDATION

GK GK2

2.84e-0334332MM15937
PathwayREACTOME_RHOBTB_GTPASE_CYCLE

DBN1 RNF20

3.01e-0335332M41738
Pubmed

Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse.

OR8G5 OR8G2P OR8G1

2.41e-071045311130974
Pubmed

An olfactory receptor gene is located in the extended human beta-globin gene cluster and is expressed in erythroid cells.

OR52A5 OR52A1

1.64e-06245210512676
Pubmed

Glycerol kinase 2 is essential for proper arrangement of crescent-like mitochondria to form the mitochondrial sheath during mouse spermatogenesis.

GK GK2

1.64e-06245230662012
Pubmed

Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species.

OR7A5 OR8G2P OR8G1

4.02e-06244539119360
Pubmed

Glycerol kinase-like proteins cooperate with Pld6 in regulating sperm mitochondrial sheath formation and male fertility.

GK GK2

4.91e-06345228852571
Pubmed

Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.

OR7A5 OR8G2P OR8G1

5.79e-062745332061665
Pubmed

The glycerol kinase gene family: structure of the Xp gene, and related intronless retroposons.

GK GK2

1.63e-0554527987308
Pubmed

Retrotransposition of glycerol kinase-related genes from the X chromosome to autosomes: functional and evolutionary aspects.

GK GK2

3.42e-05745210444329
Pubmed

Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation.

SLC26A9 BACH1

4.56e-05845231578032
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

UTP20 PKN2 DBN1 MYCBP2 WDR44 BACH1 RNF20

5.72e-0577445715302935
Pubmed

The human olfactory receptor gene family.

OR8G5 OR52A5 OR7A5 OR52A1 OR8G2P OR8G1

6.71e-0554145614983052
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ELP6 PKN2 DBN1 MYCBP2 WDR44 LPP

7.27e-0554945638280479
Pubmed

Different evolutionary processes shaped the mouse and human olfactory receptor gene families.

OR8G5 OR52A5 OR7A5 OR8G2P OR8G1

7.69e-0534045511875048
Pubmed

The olfactory receptor gene superfamily of the mouse.

OR8G5 OR52A5 OR7A5 OR8G2P OR8G1

7.69e-0534045511802173
Pubmed

A unified nomenclature for vertebrate olfactory receptors.

OR8G5 OR52A5 OR7A5 OR8G2P OR8G1

8.01e-0534345532295537
Pubmed

Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.

OR8G5 OR52A5 OR7A5 OR8G2P OR8G1

8.34e-0534645514611657
Pubmed

Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters.

OR52A5 OR52A1

1.70e-041545211121057
Pubmed

Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.

KLHL29 MYCBP2 WDR44 LPP

3.84e-0426545419240061
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

UTP20 MYCBP2 TBC1D1 RNF20

5.05e-0428545432838362
Pubmed

TopBP1 controls BLM protein level to maintain genome stability.

NEK11 TOP3A

6.50e-042945224239288
Pubmed

Genome-wide association study of periodontal pathogen colonization.

PKN2 TBC1D1

7.43e-043145222699663
Pubmed

Parallel SCF adaptor capture proteomics reveals a role for SCFFBXL17 in NRF2 activation via BACH1 repressor turnover.

WDR44 BACH1

1.00e-033645224035498
Cytoband11q24.2

OR8G5 OR8G2P OR8G1

3.35e-056345311q24.2
CytobandEnsembl 112 genes in cytogenetic band chr11q24

OR8G5 OR8G2P OR8G1

8.84e-04191453chr11q24
GeneFamilyGlycerol kinases

GK GK2

5.43e-056352568
GeneFamilyOlfactory receptors, family 8

OR8G5 OR8G2P OR8G1

1.15e-0449353155
GeneFamilyDyneins, axonemal

DNAH12 DNAH9

4.86e-0417352536
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SMYD1 ASH1L

1.96e-0334352487
GeneFamilyBasic leucine zipper proteins|BTB domain containing

KLHL29 ZBTB48 BACH1

2.19e-03134353861
GeneFamilyOlfactory receptors, family 52

OR52A5 OR52A1

4.04e-0349352165
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ADGB TMEM67 DNAH12 DNAH9 NEK11

6.57e-07164455fd30c55d0d75ef8b9396435d836187168095152b
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9 NEK11

7.62e-0716945514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.19e-061854555e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCelltumor_Lung-Epithelial_cells-tS3|Epithelial_cells / Location, Cell class and cell subclass

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.26e-061874553cea677279e71fdb9879530dea10a5e6393beacd
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.32e-061894553e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.36e-061904559ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.36e-06190455833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.39e-06191455e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCellnucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.39e-061914559d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCellnucseq-Epithelial-Epithelial_Airway|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.39e-061914551c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.47e-061934550e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.47e-06193455ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.50e-061944554a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.50e-061944551ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.54e-061954553486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.54e-06195455e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.58e-0619645527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.58e-06196455d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.62e-061974556865f4831eb23794fb88a8649d48d497bbae3f44
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.62e-0619745571fea4aa6ce96c7693fa94792d08770622873850
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.62e-0619745574a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.62e-06197455d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.62e-06197455e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.66e-06198455ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.75e-062004559ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.75e-06200455cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.75e-0620045579e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.75e-06200455873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellBronchus_Control_(B.)-Epithelial-TX-Ciliated|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

ADGB TMEM67 DNAH12 DNAH9 NEK11

1.75e-062004556a2ccc71a0cbe04a542c379b28b5006de53981c3
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

ADGB DNAH12 DNAH9 NEK11

2.42e-0516745426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM67 DNAH12 DNAH9 NEK11

2.78e-05173454c3762655caa79ac4879876f470d32578a3c93b01
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB DNAH12 DNAH9 NEK11

2.97e-05176454dee780cfa85234a7cd7bf440b66b84cec959893e
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB DNAH12 DNAH9 NEK11

3.11e-051784543b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9

3.18e-051794545e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

ADGB TMEM67 DNAH12 DNAH9

3.39e-05182454e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

ADGB TMEM67 DNAH12 DNAH9

3.39e-05182454e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB DNAH12 DNAH9 NEK11

3.54e-05184454797b6a6d6f6aafae98f75ca8bffe8263f8d3ff9b
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB DNAH12 DNAH9 NEK11

3.54e-0518445477d5b60a20b277f589b18f7a131142a7ef2dac17
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB DNAH12 DNAH9 NEK11

3.69e-0518645476033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ADGB DNAH12 DNAH9 NEK11

3.69e-0518645485787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB TMEM67 DNAH12 DNAH9

3.77e-051874542b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9

3.93e-05189454c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ADGB TMEM67 DNAH12 DNAH9

4.01e-05190454426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellEpithelial_cells-Ciliated_cells-A|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ADGB DNAH12 DNAH9 NEK11

4.01e-05190454549d813a8f23b175875e53347928941f143e236c
ToppCellASK428-Epithelial-Ciliated|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ADGB DNAH12 DNAH9 NEK11

4.09e-051914540c4b926a28bc94f3cf4d68a911c0a189f6ff505e
ToppCellE18.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB DNAH12 DNAH9 NEK11

4.09e-05191454acd844b477a069b2dcf07b2998e1b5c87dc0eb94
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

ADGB DNAH12 DNAH9 TOP3A

4.09e-05191454e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB TMEM67 DNAH12 DNAH9

4.18e-05192454be592e661367affced9ebe80849b466e6adb3a34
ToppCellIPF-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9

4.18e-05192454d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCellCOPD-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9

4.18e-05192454eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCellIPF-Epithelial-Ciliated|IPF / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9

4.18e-05192454354adc1354bf596fbc60dd45c0169688e6f45165
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB TMEM67 DNAH12 DNAH9

4.26e-051934540b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellControl-Epithelial-Ciliated|World / Disease state, Lineage and Cell class

ADGB TMEM67 DNAH12 DNAH9

4.35e-05194454958e648138676d46698090b4046cb484083ae449
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB TMEM67 DNAH12 DNAH9

4.35e-051944547a7ddccfe72a4a0dc4d1a5c809988f0069f9f1a3
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRF5 PKN2 BACH1 ASH1L

4.35e-05194454e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellBronchial_Brush-Epithelial-Ciliated_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

ADGB TMEM67 DNAH12 DNAH9

4.35e-05194454b4ce60c06568123008b1081d644733cb91c28f51
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9

4.44e-05195454649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9

4.44e-05195454129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB TMEM67 DNAH12 DNAH9

4.44e-051954543e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB DNAH12 DNAH9 NEK11

4.44e-051954549651ee03738226ee10e901f8b9ec6a417eb9c301
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Mesenchymal-Cilia-bearing_cell|3m / Sample Type, Dataset, Time_group, and Cell type.

ADGB DNAH12 DNAH9 NEK11

4.89e-052004540d14a950172a56b11fdebee8f4e13b0c10e0d592
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

ADGB DNAH12 DNAH9 NEK11

4.89e-05200454f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

ADGB TMEM67 DNAH12 DNAH9

4.89e-05200454bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

ADGB DNAH12 DNAH9 NEK11

4.89e-05200454177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAH12 FBXO10 OR8G1

2.30e-04118453bc65345ee8e59fbda60f345696192376cdbf54b8
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADGB DNAH12 PTPN20

3.49e-0413645367d736096d6b6ddb4722809557f5e987063b8d23
ToppCellSubstantia_nigra-Macroglia-CSF_related|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADGB DNAH12 PTPN20

3.49e-0413645347663c5d81c766a333207a44fc5b58b07309ee76
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)--|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADGB DNAH12 PTPN20

3.49e-041364536d2e5b871f4cf8d64e6fe0be666fb3490797c635
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL-Ependyma.Ccdc153_(Ccdc153)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADGB DNAH12 PTPN20

3.49e-04136453fd4269d194c7c11c6ab4383393a01efab05cbace
ToppCellSubstantia_nigra-Macroglia-CSF_related-EPENDYMAL|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ADGB DNAH12 PTPN20

3.49e-041364533f6cec8d52c84191f7f6e2dd4dc47524dfd5b21b
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ADGB ERMP1 OR8G5

4.13e-041444535e948d4cb913ccd8f82262a1b4d20967aadab3ab
ToppCellCiliated_cells-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

ADGB DNAH12 AFM

4.30e-0414645320f080318e9cbfd9b8b90a5e9f704d6d85b969ee
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGB DNAH9 PTPN20

4.47e-04148453d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGB DNAH9 PTPN20

4.47e-04148453c8e93b87212f55774223caa385859c566fa1981f
ToppCellCiliated_cells-B-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB DNAH12 DNAH9

4.56e-041494536399c5a2f06d79f020dece252526f1c0c110d569
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

ADGB DNAH12 DNAH9

4.74e-041514538216462e723fec2797387929dde095370947e10a
ToppCellSmart-seq2-thymus_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TMEM67 UTP20 MYCBP2

5.21e-04156453cea7b4f133272499e77ed451db91f699cff6a4bb
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE MYCBP2 WDR44

5.82e-0416245393bd29c52846c3156b8b0d2e39c552373efdfe93
ToppCellCiliated_cells-A-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

ADGB DNAH12 DNAH9

5.92e-0416345343194c6127df1ce3d29242f719645de3c11fd7c0
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM67 FBXO10 ACE

6.03e-04164453b77995958c938e10a526118f75d78cee72e0b207
ToppCellCiliated_cells-A-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

DNAH12 DNAH9 NEK11

6.14e-041654530ebdbbdb151fb797335013d5838af1c7bbc45b06
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DNAH9 AFM RNF212B

6.36e-041674533edb0570e583bb527165bcd8a4c25a042054043b
ToppCell15-Distal-Epithelial-Multiciliated_precursor|Distal / Age, Tissue, Lineage and Cell class

ADGB DNAH12 DNAH9

6.36e-04167453442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

OR8G5 ACE PIGM

6.36e-04167453a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGB DBN1 BACH1

6.47e-04168453ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB DNAH12 DNAH9

6.47e-04168453fa7c0303918cea04e3f4c4f3cb079be19004d214
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADGB DNAH12 DNAH9

6.47e-041684537edcab103c69e928d5c19a0d218ffb3ae32f9e70
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ADGB DNAH12 NEK11

6.47e-041684539a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

ADGB DNAH12 DNAH9

6.58e-04169453425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADGB DBN1 SMYD1

6.58e-041694539c9bb1b32fc6e22359424a262178906c3954415d
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADGB DNAH12 DNAH9

6.58e-04169453fba841664939c771881ba97f14ef1df6635c04ff
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|390C / Donor, Lineage, Cell class and subclass (all cells)

GK OR8G5 ACE

6.69e-041704533a7121d045f9ae54583b0f5f7436abf3665a1bce
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GK ACE DNAH9

6.69e-041704538e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GK ACE DNAH9

6.69e-04170453f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

DNAH12 DNAH9 NEK11

6.81e-0417145374be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GK AFM RNF212B

6.81e-04171453f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCelldroplet-Kidney-nan-3m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GK ACE PAQR7

6.81e-0417145305fcc72df50a380a913821b5781d9621df37d328
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GK ACE PAQR7

6.81e-0417145348fc4eca18b102b5ec5050f758281292ee8e10c6
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGB TMEM67 MYCBP2

6.92e-041724533f784aed340b50ddbec3f7dc0a5279180d38a2bb
ToppCellwk_08-11-Epithelial-Proximal_epithelial-Deuterosomal|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ADGB DNAH12 DNAH9

6.92e-0417245308ad76412c9cc3504141797b44b88478ced87476
Diseaseglycerol kinase deficiency (implicated_via_orthology)

GK GK2

6.22e-063432DOID:0060363 (implicated_via_orthology)
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

TMEM67 ACE

2.46e-0416432DOID:0110861 (implicated_via_orthology)
Diseaseproteinuria (implicated_via_orthology)

TMEM67 ACE

8.79e-0430432DOID:576 (implicated_via_orthology)
DiseaseLewy body dementia

SLC26A9 ASH1L

1.49e-0339432EFO_0006792
Diseaseinsulin sensitivity measurement, glucose homeostasis measurement

PKN2 LPP

1.80e-0343432EFO_0004471, EFO_0006896

Protein segments in the cluster

PeptideGeneStartEntry
HNIEESCFQFLKFKF

BACH1

116

O14867
NFHSFNVEKQQLCKC

ASH1L

2261

Q9NR48
DAVLTKCFHVFCFEC

RNF20

931

Q5VTR2
FVSFVLQFQFHEALC

ACE

531

P12821
EDFCVCFQNIYIFHK

ADGB

636

Q8N7X0
INPAVDHCCKTNFAF

AFM

491

P43652
CQVKFCTFKNTHIFL

FBXO10

221

Q9UK96
LNCCFDQVHVFKPAT

CMTR2

291

Q8IYT2
NCKVCFVALIQSFSH

ELP6

46

Q0PNE2
CVFFAVQVLECHFQV

CDAN1

366

Q8IWY9
VFFDISLFVHCCFLV

ERMP1

526

Q7Z2K6
CNQCFRKDGAHFFVT

RNF212B

6

A8MTL3
LCKTNVINHYFCDLF

OR8G2P

181

Q6IF36
HFFCELNQVIQLACS

OR7A5

176

Q15622
VQFCKFDLINHYFCD

OR8G1

166

Q15617
VQFCKFDVINHYFCD

OR8G5

201

Q8NG78
HKCQVVFFLLAAAFF

PAQR7

241

Q86WK9
FTNKCHIAFAALEAV

GK3P

386

Q14409
ARFKAFNTCIAHICV

OR52A1

236

Q9UKL2
ARFKAFNTCIAHICV

OR52A5

236

Q9H2C5
QCTFIKFFLHQQACF

DNAH12

1761

Q6ZR08
IVKFHASFVEQDNFC

NEK11

91

Q8NG66
VFHVDCFTCIICNNK

LPP

436

Q93052
CACASHVAKVAEFFQ

DBN1

96

Q16643
AQQIFSCKHCPSTFF

INSM2

521

Q96T92
VDVVFCAIVKNCSFN

PTPN20

366

Q4JDL3
FTNKCHIAFAALEAV

GK2

386

Q14410
NIFKALFCCFRAQHV

CTDSP2

36

O14595
CHIAFAALEAVCFQT

GK

396

P32189
DEVKHCFANICDAQF

DNAH9

1816

Q9NYC9
FFCVVDLACQNFILA

TMEM67

946

Q5HYA8
LFLCKTNVINHYFCD

OR8G3P

166

P0DMU2
NFHLVVNCFKCVTIL

UTP20

2176

O75691
NFFGSFFKIHVICCA

SLC26A9

376

Q7LBE3
AVVFDSLVNFVCHTC

SMYD1

41

Q8NB12
EAVLQECHNTFTACF

MYCBP2

1536

O75592
VNLFACFQTKEHVCF

PKN2

721

Q16513
TDVSALFCCNKAFVF

SLC35F4

276

A4IF30
LCKTACVAATFFIHF

ADGRF5

1081

Q8IZF2
VCEFCSHAFTQKANL

ZBTB48

466

P10074
HFVCYVFQCTNEALV

TBC1D1

346

Q86TI0
LCCFQHIDFVTAIAF

WDR44

641

Q5JSH3
FIVRHFLACCSQDAQ

TOP3A

436

Q13472
CNECGKAFVVFQHFI

ZNF404

161

Q494X3
GNIKHFCNLFCVLEF

ZMYM6

576

O95789
FCNLFCVLEFCHQQI

ZMYM6

581

O95789
CCFLHTSIFVTFNKV

PIGM

316

Q9H3S5
FHTFCKVCVSFLEKQ

KLHL29

416

Q96CT2