Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase inhibitor activity	IPO5 IQGAP2 IQGAP1	7.97e-06	13	62	3	GO:0005095
GeneOntologyMolecularFunction	11-beta-hydroxysteroid dehydrogenase [NAD(P)+] activity	HSD11B1 HSD11B2	9.49e-06	2	62	2	GO:0003845
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	IQGAP2 ANXA8L1 ANXA8 IQGAP1	1.61e-05	49	62	4	GO:0005547
GeneOntologyMolecularFunction	Krueppel-associated box domain binding	HDAC1 HDAC2	2.84e-05	3	62	2	GO:0035851
GeneOntologyMolecularFunction	protein decrotonylase activity	HDAC1 HDAC2	9.43e-05	5	62	2	GO:0160008
GeneOntologyMolecularFunction	histone decrotonylase activity	HDAC1 HDAC2	9.43e-05	5	62	2	GO:0160009
GeneOntologyMolecularFunction	acetylglucosaminyltransferase activity	MGAT3 EXTL3 LARGE1	4.19e-04	47	62	3	GO:0008375
GeneOntologyMolecularFunction	phosphatidylinositol binding	IQGAP2 SBF2 ANXA8L1 ANXA8 IQGAP1 ITPR2	4.37e-04	316	62	6	GO:0035091
GeneOntologyMolecularFunction	actin filament binding	IQGAP2 ANXA8L1 ANXA8 CAPZA3 IQGAP1	6.94e-04	227	62	5	GO:0051015
GeneOntologyMolecularFunction	protein kinase A catalytic subunit binding	GSK3A RYR2	1.11e-03	16	62	2	GO:0034236
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR2 ITPR2	1.41e-03	18	62	2	GO:0015278
GeneOntologyMolecularFunction	calcium ion binding	CAPN14 ANXA8L1 ANXA8 DNASE1L2 ADGRL3 RYR2 IQGAP1 ITPR2	2.13e-03	749	62	8	GO:0005509
GeneOntologyMolecularFunction	histone deacetylase activity	HDAC1 HDAC2	2.51e-03	24	62	2	GO:0004407
GeneOntologyMolecularFunction	protein kinase activity	JAK2 BMPR1A CSNK2A2 IRAK3 MERTK MAPK7 GSK3A	2.51e-03	600	62	7	GO:0004672
GeneOntologyMolecularFunction	protein lysine deacetylase activity	HDAC1 HDAC2	2.72e-03	25	62	2	GO:0033558
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC35D1 PIEZO2 SLC15A2 SLC16A2 SLC22A5 ANO1 TRPV6 SLC33A1 RYR2 ITPR2	3.24e-03	1180	62	10	GO:0022857
GeneOntologyMolecularFunction	lipid binding	IQGAP2 SBF2 ANXA8L1 ANXA8 TMEM97 HSD11B1 HSD11B2 IQGAP1 ITPR2	3.28e-03	988	62	9	GO:0008289
GeneOntologyMolecularFunction	phosphatidylinositol phosphate binding	IQGAP2 ANXA8L1 ANXA8 IQGAP1	3.40e-03	199	62	4	GO:1901981
GeneOntologyBiologicalProcess	positive regulation of protein localization	IPO5 JAK2 STAC2 MGAT3 CSNK2A2 ANO1 TMEM97 ITGB2 GSK3A IQGAP1	9.72e-06	591	62	10	GO:1903829
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly	IQGAP2 IQGAP1	2.66e-05	3	62	2	GO:1903475
GeneOntologyBiologicalProcess	mitotic actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP1	2.66e-05	3	62	2	GO:1903479
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in mitotic cytokinesis	IQGAP2 IQGAP1	2.66e-05	3	62	2	GO:1902407
GeneOntologyBiologicalProcess	negative regulation of phospholipase A2 activity	ANXA8L1 ANXA8	2.66e-05	3	62	2	GO:1900138
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly actin filament organization	IQGAP2 IQGAP1	5.31e-05	4	62	2	GO:2000689
GeneOntologyBiologicalProcess	fungiform papilla formation	HDAC1 HDAC2	5.31e-05	4	62	2	GO:0061198
GeneOntologyBiologicalProcess	negative regulation of phospholipase activity	ANXA8L1 ANXA8	8.84e-05	5	62	2	GO:0010519
GeneOntologyBiologicalProcess	regulation of cell fate specification	BMPR1A HDAC1 HDAC2	8.94e-05	29	62	3	GO:0042659
GeneOntologyBiologicalProcess	positive regulation of signaling receptor activity	JAK2 HDAC1 HDAC2	1.32e-04	33	62	3	GO:2000273
GeneOntologyBiologicalProcess	fungiform papilla morphogenesis	HDAC1 HDAC2	1.32e-04	6	62	2	GO:0061197
GeneOntologyBiologicalProcess	hair follicle placode formation	HDAC1 HDAC2	1.32e-04	6	62	2	GO:0060789
GeneOntologyBiologicalProcess	response to interleukin-3	JAK2 GSK3A	1.85e-04	7	62	2	GO:0036015
GeneOntologyBiologicalProcess	cellular response to interleukin-3	JAK2 GSK3A	1.85e-04	7	62	2	GO:0036016
GeneOntologyBiologicalProcess	fungiform papilla development	HDAC1 HDAC2	1.85e-04	7	62	2	GO:0061196
GeneOntologyBiologicalProcess	positive regulation of establishment of protein localization	IPO5 JAK2 CSNK2A2 ANO1 TMEM97 ITGB2 GSK3A	2.01e-04	403	62	7	GO:1904951
GeneOntologyBiologicalProcess	negative regulation of serine-type peptidase activity	ANXA8L1 ANXA8	2.46e-04	8	62	2	GO:1902572
GeneOntologyBiologicalProcess	negative regulation of serine-type endopeptidase activity	ANXA8L1 ANXA8	2.46e-04	8	62	2	GO:1900004
GeneOntologyBiologicalProcess	actomyosin contractile ring assembly	IQGAP2 IQGAP1	3.16e-04	9	62	2	GO:0000915
GeneOntologyBiologicalProcess	assembly of actomyosin apparatus involved in cytokinesis	IQGAP2 IQGAP1	3.16e-04	9	62	2	GO:0000912
GeneOntologyBiologicalProcess	regulation of body fluid levels	JAK2 HTR4 ANXA8L1 ANO1 ANXA8 HSD11B2 MERTK	3.52e-04	442	62	7	GO:0050878
GeneOntologyBiologicalProcess	regulation of serine-type peptidase activity	ANXA8L1 ANXA8	3.94e-04	10	62	2	GO:1902571
GeneOntologyBiologicalProcess	regulation of phospholipase A2 activity	ANXA8L1 ANXA8	3.94e-04	10	62	2	GO:0032429
GeneOntologyBiologicalProcess	regulation of serine-type endopeptidase activity	ANXA8L1 ANXA8	3.94e-04	10	62	2	GO:1900003
GeneOntologyBiologicalProcess	actomyosin contractile ring organization	IQGAP2 IQGAP1	3.94e-04	10	62	2	GO:0044837
GeneOntologyBiologicalProcess	cardiac muscle cell development	BMPR1A GSK3A HDAC2 LARGE1	4.99e-04	122	62	4	GO:0055013
GeneOntologyBiologicalProcess	regulation of cell fate commitment	BMPR1A HDAC1 HDAC2	5.44e-04	53	62	3	GO:0010453
GeneOntologyBiologicalProcess	tongue morphogenesis	HDAC1 HDAC2	5.75e-04	12	62	2	GO:0043587
GeneOntologyBiologicalProcess	negative regulation of glycogen biosynthetic process	GRB10 GSK3A	5.75e-04	12	62	2	GO:0045719
GeneOntologyBiologicalProcess	negative regulation of protein catabolic process	MGAT3 CSNK2A2 CAMLG IRAK3	6.52e-04	131	62	4	GO:0042177
GeneOntologyBiologicalProcess	cardiac cell development	BMPR1A GSK3A HDAC2 LARGE1	6.71e-04	132	62	4	GO:0055006
GeneOntologyCellularComponent	endoplasmic reticulum membrane	SLC35D1 OR8K1 MOGAT1 CAMLG COPB2 SEC11C TMEM97 ERMP1 EXTL3 HSD11B1 HSD11B2 SLC33A1 RYR2 ITPR2	1.97e-05	1293	62	14	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	SLC35D1 OR8K1 MOGAT1 CAMLG COPB2 SEC11C TMEM97 ERMP1 EXTL3 HSD11B1 HSD11B2 SLC33A1 RYR2 ITPR2	2.08e-05	1299	62	14	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	SLC35D1 OR8K1 MOGAT1 CAMLG COPB2 SEC11C TMEM97 ERMP1 EXTL3 HSD11B1 HSD11B2 SLC33A1 RYR2 ITPR2	2.63e-05	1327	62	14	GO:0042175
GeneOntologyCellularComponent	PcG protein complex	SCML2 CSNK2A2 HDAC2	4.95e-04	52	62	3	GO:0031519
GeneOntologyCellularComponent	CHD-type complex	HDAC1 HDAC2	1.14e-03	17	62	2	GO:0090545
GeneOntologyCellularComponent	NuRD complex	HDAC1 HDAC2	1.14e-03	17	62	2	GO:0016581
Domain	AnnexinVIII	ANXA8L1 ANXA8	1.05e-05	2	61	2	IPR009115
Domain	RasGAP_C	IQGAP2 IQGAP1	3.14e-05	3	61	2	IPR000593
Domain	RasGAP_C	IQGAP2 IQGAP1	3.14e-05	3	61	2	PF03836
Domain	His_deacetylse_1	HDAC1 HDAC2	6.27e-05	4	61	2	IPR003084
Domain	RIH_assoc	RYR2 ITPR2	1.56e-04	6	61	2	PF08454
Domain	RIH_assoc-dom	RYR2 ITPR2	1.56e-04	6	61	2	IPR013662
Domain	RIH_dom	RYR2 ITPR2	1.56e-04	6	61	2	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR2	1.56e-04	6	61	2	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR2	1.56e-04	6	61	2	IPR015925
Domain	-	RYR2 ITPR2	1.56e-04	6	61	2	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR2	1.56e-04	6	61	2	PF01365
Domain	Ins145_P3_rec	RYR2 ITPR2	1.56e-04	6	61	2	PF08709
Domain	MIR	RYR2 ITPR2	4.64e-04	10	61	2	PS50919
Domain	MIR	RYR2 ITPR2	4.64e-04	10	61	2	PF02815
Domain	MIR	RYR2 ITPR2	4.64e-04	10	61	2	SM00472
Domain	MIR_motif	RYR2 ITPR2	4.64e-04	10	61	2	IPR016093
Domain	Hist_deacetyl	HDAC1 HDAC2	5.66e-04	11	61	2	PF00850
Domain	His_deacetylse_dom	HDAC1 HDAC2	5.66e-04	11	61	2	IPR023801
Domain	-	HDAC1 HDAC2	5.66e-04	11	61	2	3.40.800.20
Domain	His_deacetylse	HDAC1 HDAC2	5.66e-04	11	61	2	IPR000286
Domain	PROTEIN_KINASE_ATP	JAK2 BMPR1A CSNK2A2 IRAK3 MERTK MAPK7 GSK3A	7.18e-04	459	61	7	PS00107
Domain	ANX	ANXA8L1 ANXA8	8.00e-04	13	61	2	SM00335
Domain	ANNEXIN	ANXA8L1 ANXA8	8.00e-04	13	61	2	PS00223
Domain	Annexin_repeat_CS	ANXA8L1 ANXA8	8.00e-04	13	61	2	IPR018252
Domain	Annexin	ANXA8L1 ANXA8	8.00e-04	13	61	2	PF00191
Domain	Annexin_repeat	ANXA8L1 ANXA8	8.00e-04	13	61	2	IPR018502
Domain	-	ANXA8L1 ANXA8	8.00e-04	13	61	2	1.10.220.10
Domain	Annexin	ANXA8L1 ANXA8	9.31e-04	14	61	2	IPR001464
Domain	RasGAP	IQGAP2 IQGAP1	9.31e-04	14	61	2	SM00323
Domain	RasGAP_CS	IQGAP2 IQGAP1	9.31e-04	14	61	2	IPR023152
Domain	MFS_dom	SLC15A2 SLC16A2 SLC22A5 SLC33A1	9.63e-04	134	61	4	IPR020846
Domain	Prot_kinase_dom	JAK2 BMPR1A CSNK2A2 IRAK3 MERTK MAPK7 GSK3A	1.04e-03	489	61	7	IPR000719
Domain	RasGAP	IQGAP2 IQGAP1	1.07e-03	15	61	2	PF00616
Domain	RAS_GTPASE_ACTIV_1	IQGAP2 IQGAP1	1.07e-03	15	61	2	PS00509
Domain	RAS_GTPASE_ACTIV_2	IQGAP2 IQGAP1	1.07e-03	15	61	2	PS50018
Domain	PROTEIN_KINASE_DOM	JAK2 BMPR1A CSNK2A2 IRAK3 MERTK MAPK7 GSK3A	1.09e-03	493	61	7	PS50011
Domain	-	IQGAP2 IQGAP1	1.22e-03	16	61	2	1.10.506.10
Domain	Protein_kinase_ATP_BS	JAK2 BMPR1A CSNK2A2 MERTK MAPK7 GSK3A	1.45e-03	379	61	6	IPR017441
Domain	RasGAP_dom	IQGAP2 IQGAP1	1.55e-03	18	61	2	IPR001936
Domain	IQ	IQGAP2 UBE3C IQGAP1	1.62e-03	71	61	3	PF00612
Domain	Kinase-like_dom	JAK2 BMPR1A CSNK2A2 IRAK3 MERTK MAPK7 GSK3A	1.87e-03	542	61	7	IPR011009
Domain	IQ	IQGAP2 UBE3C IQGAP1	2.36e-03	81	61	3	SM00015
Domain	IQ_motif_EF-hand-BS	IQGAP2 UBE3C IQGAP1	3.18e-03	90	61	3	IPR000048
Domain	IQ	IQGAP2 UBE3C IQGAP1	3.49e-03	93	61	3	PS50096
Domain	Sc_DH/Rdtase_CS	HSD11B1 HSD11B2	5.83e-03	35	61	2	IPR020904
Domain	Ser/Thr_kinase_AS	BMPR1A CSNK2A2 IRAK3 MAPK7 GSK3A	6.15e-03	357	61	5	IPR008271
Domain	Ion_trans_dom	TRPV6 RYR2 ITPR2	6.16e-03	114	61	3	IPR005821
Domain	Ion_trans	TRPV6 RYR2 ITPR2	6.16e-03	114	61	3	PF00520
Domain	PROTEIN_KINASE_ST	BMPR1A CSNK2A2 IRAK3 MAPK7 GSK3A	6.51e-03	362	61	5	PS00108
Domain	Pkinase	BMPR1A CSNK2A2 IRAK3 MAPK7 GSK3A	8.04e-03	381	61	5	PF00069
Domain	Pkinase_Tyr	JAK2 BMPR1A MERTK	8.65e-03	129	61	3	PF07714
Pathway	WP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION	ANXA8L1 ANXA8 HSD11B1 HSD11B2	4.31e-06	32	49	4	MM15850
Pubmed	Regulation of histone deacetylase 2 by protein kinase CK2.	CSNK2A2 HDAC1 HDAC2	3.00e-07	8	62	3	12082111
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	JAK2 BMPR1A CSNK2A2 IRAK3 MERTK MAPK7 NFS1 GSK3A HDAC1 HDAC2 ITPR2	5.57e-07	910	62	11	36736316
Pubmed	PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.	SCML2 CSNK2A2 HDAC1 HDAC2	8.82e-07	41	62	4	22325352
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	JAK2 GRB10 EXTL3 NFS1 DNASE1L2 HDAC1 HDAC2	2.00e-06	329	62	7	17474147
Pubmed	The lysine deacetylase activity of histone deacetylases 1 and 2 is required to safeguard zygotic genome activation in mice and cattle.	HDAC1 HDAC2	3.13e-06	2	62	2	35575026
Pubmed	Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis.	HDAC1 HDAC2	3.13e-06	2	62	2	23792463
Pubmed	Expression profiles of cortisol-inactivating enzyme, 11β-hydroxysteroid dehydrogenase-2, in human epidermal tumors and its role in keratinocyte proliferation.	HSD11B1 HSD11B2	3.13e-06	2	62	2	23362866
Pubmed	Glucocorticoid synthesis-related genes: HSD11B1 and HSD11B2 in hypertensive disorders in pregnancy.	HSD11B1 HSD11B2	3.13e-06	2	62	2	23659736
Pubmed	Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts.	HDAC1 HDAC2	3.13e-06	2	62	2	19531758
Pubmed	11 beta-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess.	HSD11B1 HSD11B2	3.13e-06	2	62	2	9034789
Pubmed	TaqI polymorphisms at the annexin VIII locus (ANX8).	ANXA8L1 ANXA8	3.13e-06	2	62	2	1364010
Pubmed	11Beta-hydroxysteroid dehydrogenases in human endometrium.	HSD11B1 HSD11B2	3.13e-06	2	62	2	16406280
Pubmed	Casein kinase 2 regulates in vivo bone formation through its interaction with bone morphogenetic protein receptor type Ia.	BMPR1A CSNK2A2	3.13e-06	2	62	2	21763800
Pubmed	Histone deacetylases 1 and 2 inhibition suppresses cytokine production and osteoclast bone resorption in vitro.	HDAC1 HDAC2	3.13e-06	2	62	2	31222845
Pubmed	Annexin A8 controls leukocyte recruitment to activated endothelial cells via cell surface delivery of CD63.	ANXA8L1 ANXA8	3.13e-06	2	62	2	24769558
Pubmed	Differential expression of IQGAP1/2 in Hepatocellular carcinoma and its relationship with clinical outcomes.	IQGAP2 IQGAP1	3.13e-06	2	62	2	24998570
Pubmed	The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis.	HDAC1 HDAC2	3.13e-06	2	62	2	24525021
Pubmed	HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1.	HDAC1 HDAC2	3.13e-06	2	62	2	11287668
Pubmed	Human hypertension caused by mutations in the kidney isozyme of 11 beta-hydroxysteroid dehydrogenase.	HSD11B1 HSD11B2	3.13e-06	2	62	2	7670488
Pubmed	Depot-specific regulation of the conversion of cortisone to cortisol in human adipose tissue.	HSD11B1 HSD11B2	3.13e-06	2	62	2	18388900
Pubmed	CK2.1, a novel peptide, induces articular cartilage formation in vivo.	BMPR1A CSNK2A2	3.13e-06	2	62	2	27312334
Pubmed	Essential roles of HDAC1 and 2 in lineage development and genome-wide DNA methylation during mouse preimplantation development.	HDAC1 HDAC2	3.13e-06	2	62	2	31533525
Pubmed	Postdate pregnancy: changes of placental/membranes 11β-hydroxysteroid dehydrogenase mRNA and activity.	HSD11B1 HSD11B2	3.13e-06	2	62	2	24054540
Pubmed	IQGAP1 and IQGAP2 are reciprocally altered in hepatocellular carcinoma.	IQGAP2 IQGAP1	3.13e-06	2	62	2	20977743
Pubmed	Kidney cell type-specific changes in the chromatin and transcriptome landscapes following epithelial Hdac1 and Hdac2 knockdown.	HDAC1 HDAC2	3.13e-06	2	62	2	34890513
Pubmed	Histone deacetylase 1 and 2 drive differentiation and fusion of progenitor cells in human placental trophoblasts.	HDAC1 HDAC2	3.13e-06	2	62	2	32366868
Pubmed	HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells.	HDAC1 HDAC2	3.13e-06	2	62	2	21423190
Pubmed	Pressure overload-induced cardiac hypertrophy response requires janus kinase 2-histone deacetylase 2 signaling.	JAK2 HDAC2	3.13e-06	2	62	2	25380525
Pubmed	Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection.	HDAC1 HDAC2	3.13e-06	2	62	2	24335310
Pubmed	Differences in expression and activity of 11beta-hydroxysteroid dehydrogenase type 1 and 2 in human placentas of term pregnancies according to birth weight and gender.	HSD11B1 HSD11B2	3.13e-06	2	62	2	19542242
Pubmed	Attenuation of neuronal ferroptosis in intracerebral hemorrhage by inhibiting HDAC1/2: Microglial heterogenization via the Nrf2/HO1 pathway.	HDAC1 HDAC2	3.13e-06	2	62	2	38523117
Pubmed	The Role of Placental 11-Beta Hydroxysteroid Dehydrogenase Type 1 and Type 2 Methylation on Gene Expression and Infant Birth Weight.	HSD11B1 HSD11B2	3.13e-06	2	62	2	25788665
Pubmed	Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC.	HDAC1 HDAC2	3.13e-06	2	62	2	18408217
Pubmed	Cooperative binding promotes demand-driven recruitment of AnxA8 to cholesterol-containing membranes.	ANXA8L1 ANXA8	3.13e-06	2	62	2	29306076
Pubmed	HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia.	HDAC1 HDAC2	3.13e-06	2	62	2	28579617
Pubmed	HDAC1 and HDAC2 Modulate TGF-β Signaling during Endothelial-to-Hematopoietic Transition.	HDAC1 HDAC2	3.13e-06	2	62	2	29641990
Pubmed	HDAC1 and HDAC2 restrain the intestinal inflammatory response by regulating intestinal epithelial cell differentiation.	HDAC1 HDAC2	3.13e-06	2	62	2	24040068
Pubmed	Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis.	HDAC1 HDAC2	3.13e-06	2	62	2	26174178
Pubmed	[Regulatory effect of ginsenoside Rh2 on HDAC1/2 activity and cyclin in human erythroleukemia K562 cells].	HDAC1 HDAC2	3.13e-06	2	62	2	25270209
Pubmed	Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma.	HDAC1 HDAC2	3.13e-06	2	62	2	22156779
Pubmed	Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.	RYR2 ITPR2	3.13e-06	2	62	2	28158491
Pubmed	Endothelial cell dysfunction in mice after transgenic knockout of type 2, but not type 1, 11beta-hydroxysteroid dehydrogenase.	HSD11B1 HSD11B2	3.13e-06	2	62	2	11733403
Pubmed	IQGAP1/ERK regulates fear memory formation via histone posttranslational modifications induced by HDAC2.	HDAC2 IQGAP1	3.13e-06	2	62	2	32145408
Pubmed	Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2.	HSD11B1 HSD11B2	3.13e-06	2	62	2	30902677
Pubmed	Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer.	HDAC1 HDAC2	3.13e-06	2	62	2	23251689
Pubmed	Expression of 11β-hydroxysteroid dehydrogenase enzymes in human osteosarcoma: potential role in pathogenesis and as targets for treatments.	HSD11B1 HSD11B2	3.13e-06	2	62	2	22719058
Pubmed	Expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in colorectal cancer.	HSD11B1 HSD11B2	3.13e-06	2	62	2	15172126
Pubmed	Histone deacetylase HDA-1 modulates mitochondrial stress response and longevity.	HDAC1 HDAC2	3.13e-06	2	62	2	32934238
Pubmed	IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling.	IPO5 IQGAP1	3.13e-06	2	62	2	24196961
Pubmed	Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining.	HDAC1 HDAC2	3.13e-06	2	62	2	20802485
Pubmed	Bone matrix regulates osteoclast differentiation and annexin A8 gene expression.	ANXA8L1 ANXA8	3.13e-06	2	62	2	21344395
Pubmed	Inhibition of histone deacetylase 1 (HDAC1) and HDAC2 enhances CRISPR/Cas9 genome editing.	HDAC1 HDAC2	3.13e-06	2	62	2	31799598
Pubmed	The binding of histone deacetylases and the integrity of zinc finger-like motifs of the E7 protein are essential for the life cycle of human papillomavirus type 31.	HDAC1 HDAC2	3.13e-06	2	62	2	15016876
Pubmed	Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions.	HDAC1 HDAC2	3.13e-06	2	62	2	11919195
Pubmed	Dysregulation of 11beta-hydroxysteroid dehydrogenases: implications during pregnancy and beyond.	HSD11B1 HSD11B2	3.13e-06	2	62	2	27018008
Pubmed	Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia.	HDAC1 HDAC2	3.13e-06	2	62	2	21292776
Pubmed	Development of hepatocellular carcinoma in Iqgap2-deficient mice is IQGAP1 dependent.	IQGAP2 IQGAP1	3.13e-06	2	62	2	18180285
Pubmed	Genetic dissection of histone deacetylase requirement in tumor cells.	HDAC1 HDAC2	3.13e-06	2	62	2	19416910
Pubmed	Switch of glycolysis to gluconeogenesis by dexamethasone for treatment of hepatocarcinoma.	HSD11B1 HSD11B2	3.13e-06	2	62	2	24149070
Pubmed	Expression of 11β-hydroxysteroid dehydrogenase 1 and 2 in patients with chronic rhinosinusitis and their possible contribution to local glucocorticoid activation in sinus mucosa.	HSD11B1 HSD11B2	3.13e-06	2	62	2	24810847
Pubmed	Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice.	HDAC1 HDAC2	3.13e-06	2	62	2	23287868
Pubmed	11beta-Hydroxysteroid dehydrogenase types 1 and 2 are up- and downregulated in cortisol-secreting adrenal adenomas.	HSD11B1 HSD11B2	3.13e-06	2	62	2	12109593
Pubmed	HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells.	HDAC1 HDAC2	3.13e-06	2	62	2	31071955
Pubmed	Phenotypic analysis of mice bearing targeted deletions of 11beta-hydroxysteroid dehydrogenases 1 and 2 genes.	HSD11B1 HSD11B2	3.13e-06	2	62	2	11165006
Pubmed	Annexin A8 is up-regulated during mouse mammary gland involution and predicts poor survival in breast cancer.	ANXA8L1 ANXA8	3.13e-06	2	62	2	16203777
Pubmed	Variants of 11β-hydroxysteroid dehydrogenase (HSD11B) gene type 1 and 2 in Chinese obese adolescents.	HSD11B1 HSD11B2	3.13e-06	2	62	2	24729284
Pubmed	Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers.	HDAC1 HDAC2	3.13e-06	2	62	2	25942572
Pubmed	Variable expression of 11beta Hydroxysteroid dehydrogenase (11beta-HSD) isoforms in vascular endothelial cells.	HSD11B1 HSD11B2	3.13e-06	2	62	2	18573267
Pubmed	Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function.	HDAC1 HDAC2	3.13e-06	2	62	2	19553468
Pubmed	A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog.	HDAC1 HDAC2	3.13e-06	2	62	2	24449838
Pubmed	HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells.	HDAC1 HDAC2	3.13e-06	2	62	2	20398369
Pubmed	Annexins: linking Ca2+ signalling to membrane dynamics.	ANXA8L1 ANXA8	3.13e-06	2	62	2	15928709
Pubmed	Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice.	HDAC1 HDAC2	3.13e-06	2	62	2	22307625
Pubmed	Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease.	HDAC1 HDAC2	3.13e-06	2	62	2	26116233
Pubmed	Effect of cellular differentiation on 11beta-hydroxysteroid dehydrogenase activity in the intestine.	HSD11B1 HSD11B2	3.13e-06	2	62	2	11755176
Pubmed	Dynamic distribution of HDAC1 and HDAC2 during mitosis: association with F-actin.	HDAC1 HDAC2	3.13e-06	2	62	2	23280436
Pubmed	Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL.	HDAC1 HDAC2	3.13e-06	2	62	2	25688158
Pubmed	Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse.	HDAC1 HDAC2	3.13e-06	2	62	2	23516383
Pubmed	Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection.	HDAC1 HDAC2	3.13e-06	2	62	2	19740981
Pubmed	NuRD and SIN3 histone deacetylase complexes in development.	HDAC1 HDAC2	3.13e-06	2	62	2	10904264
Pubmed	HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis.	HDAC1 HDAC2	3.13e-06	2	62	2	25648995
Pubmed	Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility.	HDAC1 HDAC2	3.13e-06	2	62	2	17639084
Pubmed	11beta-hydroxysteroid dehydrogenase type 1: a tissue-specific regulator of glucocorticoid response.	HSD11B1 HSD11B2	3.13e-06	2	62	2	15466942
Pubmed	Mitochondrial calcium overload is a key determinant in heart failure.	RYR2 ITPR2	3.13e-06	2	62	2	26217001
Pubmed	Differential HDAC1/2 network analysis reveals a role for prefoldin/CCT in HDAC1/2 complex assembly.	HDAC1 HDAC2	3.13e-06	2	62	2	30209338
Pubmed	HDAC1 and HDAC2 are differentially expressed in endometriosis.	HDAC1 HDAC2	3.13e-06	2	62	2	22344732
Pubmed	Altered activity of 11beta-hydroxysteroid dehydrogenase types 1 and 2 in skeletal muscle confers metabolic protection in subjects with type 2 diabetes.	HSD11B1 HSD11B2	3.13e-06	2	62	2	17519316
Pubmed	Comparison between placental gene expression of 11β-hydroxysteroid dehydrogenases and infantile growth at 10 months of age.	HSD11B1 HSD11B2	3.13e-06	2	62	2	24147632
Pubmed	HDAC1 and HDAC2 independently regulate common and specific intrinsic responses in murine enteroids.	HDAC1 HDAC2	3.13e-06	2	62	2	30926862
Pubmed	Human adrenal cortex and aldosterone secreting adenomas express both 11beta-hydroxysteroid dehydrogenase type 1 and type 2 genes.	HSD11B1 HSD11B2	3.13e-06	2	62	2	11956655
Pubmed	Annexins: from structure to function.	ANXA8L1 ANXA8	3.13e-06	2	62	2	11917092
Pubmed	Trans-regulation of histone deacetylase activities through acetylation.	HDAC1 HDAC2	3.13e-06	2	62	2	19822520
Pubmed	Expression profiles of human 11beta-hydroxysteroid dehydrogenases type 1 and type 2 in inflammatory bowel diseases.	HSD11B1 HSD11B2	3.13e-06	2	62	2	19022342
Pubmed	Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer.	HDAC1 HDAC2	3.13e-06	2	62	2	31692265
Pubmed	Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation.	HDAC1 HDAC2	3.13e-06	2	62	2	15297431
Pubmed	Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells.	HDAC1 HDAC2	3.13e-06	2	62	2	24958871
Pubmed	Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer.	HDAC1 HDAC2	3.13e-06	2	62	2	20585871
Pubmed	Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression.	HDAC1 HDAC2	3.13e-06	2	62	2	26129908
Pubmed	Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation.	HDAC1 HDAC2	3.13e-06	2	62	2	19412887
Pubmed	Function, gene organization and protein structures of 11beta-hydroxysteroid dehydrogenase isoforms.	HSD11B1 HSD11B2	3.13e-06	2	62	2	9370340
Cytoband	9p24	JAK2 ERMP1	5.00e-05	8	62	2	9p24
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	HDAC1 HDAC2	3.31e-05	4	43	2	989
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	HDAC1 HDAC2	1.97e-04	9	43	2	1306
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	HDAC1 HDAC2	3.59e-04	12	43	2	1243
GeneFamily	PHD finger proteins\|NuRD complex	HDAC1 HDAC2	3.59e-04	12	43	2	1305
GeneFamily	Annexins\|Endogenous ligands	ANXA8L1 ANXA8	4.24e-04	13	43	2	404
GeneFamily	Solute carriers	SLC35D1 SLC15A2 SLC16A2 SLC22A5 SLC33A1	2.36e-03	395	43	5	752
Coexpression	NAKAYA_PBMC_FLUMIST_AGE_18_50YO_7DY_IFN_SUBSET_UP	IRAK3 ITGB2 HDAC1 HDAC2	1.10e-06	33	62	4	M41050
Coexpression	MCBRYAN_PUBERTAL_BREAST_4_5WK_DN	LETMD1 SLC16A2 ANXA8L1 GRB10 ANXA8 EXTL3	9.60e-06	207	62	6	MM988
Coexpression	MCCLUNG_COCAIN_REWARD_4WK	SLC35D1 CAMLG SLC22A5 ITPR2	2.88e-05	74	62	4	M1600
Coexpression	MCCLUNG_COCAIN_REWARD_4WK	SLC35D1 CAMLG SLC22A5 ITPR2	3.20e-05	76	62	4	MM682
Coexpression	ROSS_AML_WITH_PML_RARA_FUSION	GRB10 CPA3 ANXA8 ITPR2	3.92e-05	80	62	4	M15368
Coexpression	LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_UP	IQGAP2 SMPDL3A SLC22A5 MERTK IQGAP1	7.36e-05	183	62	5	M12621
Coexpression	GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_UP	PRAMEF10 SLC15A2 TMEM97 DNASE1L2 ADGRL3	9.93e-05	195	62	5	M8140
Coexpression	GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_UP	SLC22A5 NFS1 SLC33A1 HDAC1 IQGAP1	1.09e-04	199	62	5	M5365
Coexpression	GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	IQGAP2 SMPDL3A SLC22A5 SEC11C HSD11B1	1.09e-04	199	62	5	M9179
Coexpression	GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN2_THYMOCYTE_ADULT_DN	SLC35D1 CPA3 TMEM97 HSD11B1 ITPR2	1.12e-04	200	62	5	M4560
Coexpression	MCBRYAN_PUBERTAL_BREAST_4_5WK_DN	LETMD1 SLC16A2 ANXA8L1 GRB10 EXTL3	1.17e-04	202	62	5	M12428
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 SLC16A2 ANO1 HSD11B1 ADAM32 RYR2	1.58e-07	177	61	6	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	PIEZO2 SLC16A2 ANO1 HSD11B1 ADAM32 RYR2	1.58e-07	177	61	6	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL10 ANXA8 ITGB2 GSK3A LARGE1	2.62e-06	159	61	5	709b57f992a29878cc899d760d144d36cb5cb280
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 HSD11B2 DNASE1L2 ITPR2	4.43e-06	177	61	5	6d89042bda8e244babb68929e84b25edcb545a77
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 HSD11B2 DNASE1L2 ITPR2	4.43e-06	177	61	5	daaccf1249dcf816df4caca695a944f53078291a
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 HSD11B2 DNASE1L2 ITPR2	4.43e-06	177	61	5	338bdda26796bf4e16072878c070212d1006cf57
ToppCell	3'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 HSD11B2 DNASE1L2 ITPR2	4.43e-06	177	61	5	c5a16f984c836dbf7d0faf061677844167ab612a
ToppCell	NS-moderate-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	STAC2 HSD11B2 DNASE1L2 ADGRL3 ITPR2	4.81e-06	180	61	5	8af8b4af2dc72223ac71fc027e0d4280c5dd81f8
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 SEC11C DNASE1L2 ITPR2	4.94e-06	181	61	5	40df0afcb6848202da54670e84f22d7c3a515d01
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 SEC11C DNASE1L2 ITPR2	4.94e-06	181	61	5	2b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 SEC11C DNASE1L2 ITPR2	4.94e-06	181	61	5	6aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell	5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STAC2 IQGAP2 SEC11C DNASE1L2 ITPR2	4.94e-06	181	61	5	40d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	IQGAP2 SBF2 IRAK3 MERTK ITPR2	7.10e-06	195	61	5	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	IQGAP2 IRAK3 MERTK ITGB2 ITPR2	7.46e-06	197	61	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAC2 IQGAP2 SLC22A5 MAPK7	4.08e-05	140	61	4	e442c46979d725ec82f525a001c46d971fcade4d
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MGAT3 ERMP1 ITGB2 GSK3A	5.77e-05	153	61	4	489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC15A2 HSD11B1 MERTK ITPR2	5.77e-05	153	61	4	95b28c5bd10ffb74c0993ebd565038b9818e4bd2
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC15A2 HSD11B1 MERTK ITPR2	5.77e-05	153	61	4	b09f8def40a1ea56722f3398f61a036667b61cd9
ToppCell	primary_visual_cortex-Non-neuronal-astrocyte-Astro-Astro_Aqp4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC15A2 HSD11B1 MERTK ITPR2	5.77e-05	153	61	4	3ab9d55b3db51715c1d61eca142384195ce4b54f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOGAT1 SEC11C CPA3 TRPV6	6.07e-05	155	61	4	51f6447945389649d99dcf7603b396195c631ead
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Mast_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MOGAT1 SEC11C CPA3 TRPV6	6.07e-05	155	61	4	23dc71cab28094ca0ac4d2baf4e24871ed107781
ToppCell	10x5'-Liver-Myeloid_Mac-Intestinal_macrophages\|Liver / Manually curated celltypes from each tissue	PIEZO2 SMPDL3A MERTK LARGE1	6.22e-05	156	61	4	9a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 KLHL10 ANXA8L1 HSD11B2	6.22e-05	156	61	4	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	IPF-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	STAC2 SEC11C ADGRL3 ITPR2	6.54e-05	158	61	4	67adf625a959444762d32268b3b7441f6f8b3b8c
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	KLHL10 PIEZO2 ADGRL3 RYR2	7.38e-05	163	61	4	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	lung-Club_Cells\|lung / shred on tissue and cell subclass	IQGAP2 COPB2 ANO1 ITGB2	7.55e-05	164	61	4	b12cacd499b18b96120ca6d14646aebeaed41d10
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 HTR4 GRB10 ITPR2	8.48e-05	169	61	4	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 HTR4 SLC22A5 ITPR2	8.48e-05	169	61	4	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 HTR4 SLC22A5 ITPR2	8.48e-05	169	61	4	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	control-Myeloid-Eosinophils\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	JAK2 MGAT3 SMPDL3A CPA3	8.88e-05	171	61	4	82f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCell	Influenza_Severe-B_intermediate\|World / Disease group and Cell class	MGAT3 SLC15A2 DNASE1L2 LARGE1	8.88e-05	171	61	4	4d33e1dc1efc423dbdd5f4cca6d6440a68add8d0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 HTR4 GRB10 ITPR2	9.29e-05	173	61	4	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	Fetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANO1 GRB10 ADGRL3 RYR2	9.50e-05	174	61	4	015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 HTR4 GRB10 ITPR2	9.92e-05	176	61	4	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	STAC2 IQGAP2 SMPDL3A HSD11B2	1.04e-04	178	61	4	3d6d03bc57062f74ba19fc675dd36b12b6c7115d
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	STAC2 SEC11C HSD11B2 ITPR2	1.13e-04	182	61	4	6e7dac78dc030f74e546b9f6db07556e9bb13ac2
ToppCell	cellseq-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	STAC2 SEC11C HSD11B2 ITPR2	1.13e-04	182	61	4	cd972d30519db706477c6b0c901165b81b74abed
ToppCell	control-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	JAK2 MGAT3 SMPDL3A CPA3	1.18e-04	184	61	4	fad517d047e8eaeaa5bd4f311d770880568dd13c
ToppCell	tumor_Lung-Fibroblasts-Mesothelial_cells\|tumor_Lung / Location, Cell class and cell subclass	PIEZO2 SLC16A2 ANXA8L1 ANXA8	1.18e-04	184	61	4	b0a251030d127858e68cf164be158f209a4d720f
ToppCell	Myeloid-B_(Activated_Macrophage)\|World / shred on cell class and cell subclass (v4)	MERTK ITGB2 IQGAP1 ITPR2	1.23e-04	186	61	4	33d731a7883d75e4e7db83b641cdb1e9a39938bf
ToppCell	moderate-Epithelial-Ionocyte\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	STAC2 HSD11B2 ADGRL3 ITPR2	1.25e-04	187	61	4	3e3fe2d5712a0ac477cddefe56705d4b8d8f7eac
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1A HTR4 ANO1 RYR2	1.28e-04	188	61	4	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	AT1-AT2_cells-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	BMPR1A SLC15A2 ANXA8L1 ANXA8	1.28e-04	188	61	4	be710bc957118cf426dd71c2d57e6f1b41c9a467
ToppCell	ASK454-Endothelial-Lymphatic\|Endothelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAJC13 PIEZO2 SMPDL3A NFS1	1.31e-04	189	61	4	316c857dec9383823e09f966bca62d52d933b141
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BMPR1A HTR4 ANO1 RYR2	1.31e-04	189	61	4	7ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCell	moderate-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	STAC2 HSD11B2 ADGRL3 ITPR2	1.31e-04	189	61	4	6011b747e27d61d222380a7bffdd921a68e9b657
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	IPO5 MGAT3 ANXA8 TMEM97	1.31e-04	189	61	4	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|368C / Donor, Lineage, Cell class and subclass (all cells)	IQGAP2 MERTK ITGB2 ITPR2	1.33e-04	190	61	4	cbba3d94a4c3e0b0d14f3b7c60dba5d6e097c5e3
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAK2 ANO1 ADGRL3 RYR2	1.39e-04	192	61	4	bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAK2 ANO1 ADGRL3 RYR2	1.39e-04	192	61	4	b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell	Control-Myeloid-Monocyte-derived_macrophages\|Control / group, cell type (main and fine annotations)	IQGAP2 IRAK3 MERTK ITPR2	1.41e-04	193	61	4	a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCell	Control-Endothelial-Endothelial-Gen_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIEZO2 SBF2 GRB10 ADGRL3	1.41e-04	193	61	4	e1d546165dcc2392f540162206852c4717d7306f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JAK2 ANO1 ADGRL3 RYR2	1.50e-04	196	61	4	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_3\|Classical_Monocyte / Disease condition and Cell class	DNAJC13 IQGAP2 ITGB2 IQGAP1	1.50e-04	196	61	4	15397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	IQGAP2 SBF2 IRAK3 MERTK	1.50e-04	196	61	4	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PIEZO2 SMPDL3A SBF2 IRAK3	1.50e-04	196	61	4	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JAK2 ANO1 ADGRL3 RYR2	1.50e-04	196	61	4	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	JAK2 MERTK ITGB2 IQGAP1	1.53e-04	197	61	4	e3349a381723393cd255f202afedd0c99037939b
ToppCell	Smart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage\|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	JAK2 MERTK ITGB2 IQGAP1	1.53e-04	197	61	4	e567886d69c6ea8dec87019c2ebc593793cb3107
ToppCell	nucseq-Immune-Immune_Myeloid-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IQGAP2 SMPDL3A MERTK ITPR2	1.53e-04	197	61	4	6f41c8f815851968849428ec92c16745bd01a3fb
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PIEZO2 SMPDL3A SBF2 IRAK3	1.53e-04	197	61	4	0034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCell	nucseq-Immune-Immune_Myeloid-IM-IM\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IQGAP2 SMPDL3A MERTK ITPR2	1.53e-04	197	61	4	304044ace926943b8eb588f686ecbe5d1689a809
ToppCell	COVID-19-Myeloid\|COVID-19 / group, cell type (main and fine annotations)	IQGAP2 SBF2 IRAK3 MERTK	1.56e-04	198	61	4	33f0a919188a67d2a876b52c61a1cec2c9747969
ToppCell	normal_Lung-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	PIEZO2 SMPDL3A ANO1 HSD11B1	1.56e-04	198	61	4	e0e47cf65774191981840b22905b2094b95abe0f
ToppCell	distal-1-mesenchymal-Alveolar_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANO1 HSD11B1 HSD11B2 RYR2	1.56e-04	198	61	4	6594c35ab203dc51462167c61807b0d49fa30fb2
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IQGAP2 SMPDL3A IRAK3 MERTK	1.56e-04	198	61	4	641e7be258303bb9782d19fcf8693f317581d3b8
ToppCell	distal-mesenchymal-Alveolar_Fibroblast-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 ANO1 HSD11B1 HSD11B2	1.59e-04	199	61	4	fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCell	5'-Adult-LargeIntestine-Hematopoietic-Myeloid\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IRAK3 CPA3 MERTK ITGB2	1.59e-04	199	61	4	a4785c1921a3de18a9190e4d674ede6a90f80004
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PIEZO2 ANO1 HSD11B1 RYR2	1.59e-04	199	61	4	66a79732caf2f04c09b4d9832377aa01ca477677
ToppCell	distal-mesenchymal-Alveolar_Fibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 ANO1 HSD11B1 HSD11B2	1.59e-04	199	61	4	655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell	Parenchyma_Control_(B.)-Immune-TX-TRAM-2\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	MGAT3 MOGAT1 IQGAP2 ITGB2	1.62e-04	200	61	4	7c56935446f10d202eafa1f9ee7cb0aae4c2607e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Neuronal-Intermediate\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	SLC15A2 SMPDL3A GRB10 HSD11B2	1.62e-04	200	61	4	401d50fa394fa863fa7836344110ae5c7af3250a
ToppCell	Parenchyma_COVID-19-Immune-TX-MoAM-2\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	IQGAP2 SMPDL3A MERTK ITGB2	1.62e-04	200	61	4	33c5615cbedb9e14f4433169babd3a3a51f69b4c
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	PIEZO2 ANO1 HSD11B1 RYR2	1.62e-04	200	61	4	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	mLN-(6)_Macrophage-(61)_LYVE1_Macrophage\|mLN / shred on region, Cell_type, and subtype	MOGAT1 SMPDL3A IRAK3 MERTK	1.62e-04	200	61	4	a20f5ec61d492d8a2adf695ec304b5d57296aa8f
ToppCell	mLN-Macrophage-LYVE1_Macrophage\|mLN / Region, Cell class and subclass	MOGAT1 SMPDL3A IRAK3 MERTK	1.62e-04	200	61	4	89cf739a3c2f5d30e547404f2f2ec6500cd1d65d
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PIEZO2 ANO1 HSD11B1 RYR2	1.62e-04	200	61	4	a510deaada669e690329183e18df02870bd204b3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PIEZO2 ANO1 HSD11B1 DNASE1L2	1.62e-04	200	61	4	07641f476cb1a131c2a50258b88cc13bb38c8379
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	PIEZO2 ANO1 HSD11B1 DNASE1L2	1.62e-04	200	61	4	343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIEZO2 ANO1 HSD11B1 DNASE1L2	1.62e-04	200	61	4	d0c00cdd52c2e001aec9b935f4e981ba77d0386a
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PIEZO2 ANO1 HSD11B1 RYR2	1.62e-04	200	61	4	dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCell	distal-3-mesenchymal-Alveolar_Fibroblast\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PIEZO2 ANO1 HSD11B1 HSD11B2	1.62e-04	200	61	4	20112be28f80baffad92641c9cfd7c3718967dbb
Drug	D3 F	HSD11B1 HSD11B2	7.06e-06	2	61	2	CID002799606
Drug	20beta-dihydrocortisol	HSD11B1 HSD11B2	7.06e-06	2	61	2	CID000165046
Drug	7 beta-hydroxysteroid	HSD11B1 HSD11B2	7.06e-06	2	61	2	CID000439865
Drug	valproate	HTR4 SLC22A5 TRPV6 MAPK7 GSK3A RYR2 HDAC1 HDAC2	7.76e-06	381	61	8	CID000003121
Drug	Caffeine	MOGAT1 CSNK2A2 TMEM97 HSD11B1 HSD11B2 GSK3A RYR2 HDAC1 HDAC2	8.81e-06	515	61	9	ctd:D002110
Drug	angiotensin	JAK2 CAMLG CPA3 HSD11B1 HSD11B2 MAPK7 SLC33A1	1.02e-05	282	61	7	CID003083715
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; PC3; HT_HG-U133A	JAK2 ERMP1 MAPK7 GSK3A RYR2 ITPR2	1.50e-05	198	61	6	3756_DN
Drug	11-dehydrocorticosterone	HSD11B1 HSD11B2	2.11e-05	3	61	2	ctd:C003552
Drug	FK037	SLC15A2 SLC22A5	2.11e-05	3	61	2	CID009570998
Drug	AC1NB5VE	SLC15A2 SLC22A5	2.11e-05	3	61	2	CID004487903
Drug	diethylcarbamate	HSD11B1 HSD11B2	4.22e-05	4	61	2	CID003757586
Drug	2'-hydroxyflavone	HSD11B1 HSD11B2	7.02e-05	5	61	2	CID000161860
Drug	AC1Q6O8R	HSD11B1 HSD11B2	7.02e-05	5	61	2	CID000009791
Drug	Vorinostat	HDAC1 HDAC2	7.02e-05	5	61	2	DB02546
Drug	6 beta-hydroxyprednisolone	HSD11B1 HSD11B2	7.02e-05	5	61	2	CID000152139
Disease	trimethylamine-N-oxide measurement	TTC13 UBE3C ITPR2	2.86e-06	14	60	3	EFO_0010541
Disease	Pregnancy Complications	JAK2 HSD11B2	1.22e-05	3	60	2	C0032962
Disease	Brain Tumor, Primary	IQGAP2 ITGB2 IQGAP1	4.18e-05	33	60	3	C0750974
Disease	Primary malignant neoplasm of brain	IQGAP2 ITGB2 IQGAP1	4.18e-05	33	60	3	C0750979
Disease	Recurrent Brain Neoplasm	IQGAP2 ITGB2 IQGAP1	4.18e-05	33	60	3	C0750977
Disease	Neoplasms, Intracranial	IQGAP2 ITGB2 IQGAP1	4.18e-05	33	60	3	C1527390
Disease	Benign neoplasm of brain, unspecified	IQGAP2 ITGB2 IQGAP1	4.18e-05	33	60	3	C0496899
Disease	Malignant neoplasm of brain	IQGAP2 ITGB2 IQGAP1	6.41e-05	38	60	3	C0153633
Disease	Brain Neoplasms	IQGAP2 ITGB2 IQGAP1	6.93e-05	39	60	3	C0006118
Disease	alopecia areata (is_marker_for)	HDAC1 HDAC2	1.81e-04	10	60	2	DOID:986 (is_marker_for)
Disease	Thromboembolism	JAK2 MERTK	2.65e-04	12	60	2	C0040038
Disease	smooth surface dental caries	IPO5 IRAK3 ITPR2	2.78e-04	62	60	3	EFO_0006339
Disease	pulmonary hypertension (is_marker_for)	BMPR1A HDAC1 HDAC2	3.05e-04	64	60	3	DOID:6432 (is_marker_for)
Disease	inherited metabolic disorder (is_implicated_in)	SLC22A5 HSD11B2	4.20e-04	15	60	2	DOID:655 (is_implicated_in)
Disease	type 1 diabetes mellitus (is_marker_for)	HSD11B2 HDAC1 HDAC2	4.31e-04	72	60	3	DOID:9744 (is_marker_for)
Disease	partial epilepsy	SLC33A1 ADGRL3	5.42e-04	17	60	2	EFO_0004263
Disease	Tachyarrhythmia	HTR4 RYR2	6.09e-04	18	60	2	C0080203
Disease	Tachycardia	HTR4 RYR2	6.09e-04	18	60	2	C0039231
Disease	Cardiac Arrhythmia	HTR4 SLC22A5	1.18e-03	25	60	2	C0003811
Disease	Heart valve disease	JAK2 ITGB2	1.28e-03	26	60	2	C0018824
Disease	birth weight	SLC35D1 ANO1 GRB10 CPA3 ITPR2	1.31e-03	399	60	5	EFO_0004344
Disease	Crohn's disease (is_implicated_in)	JAK2 SLC22A5	1.71e-03	30	60	2	DOID:8778 (is_implicated_in)
Disease	amyotrophic lateral sclerosis (is_implicated_in)	GSK3A ITPR2	1.94e-03	32	60	2	DOID:332 (is_implicated_in)
Disease	asthma, Eczema, allergic rhinitis	JAK2 SLC15A2 IQGAP1	1.94e-03	121	60	3	EFO_0005854, HP_0000964, MONDO_0004979

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPFLCLYYPQMLYIK	PRAMEF33	261	A0A0G2JMD5
FYKAMPYRLLLGLEY	SLC33A1	376	O00400
LNLVMYPKLGYVIYS	CAPZA3	276	Q96KX2
PFLTLQLAYMGLYKY	CAMLG	216	P49069
MYLLGYIPKDNRLYL	COPB2	561	P35606
RRKYFYLVGYGMPAL	ADGRL3	966	Q9HAR2
LLIYMDYPRYLGAVF	ADAM32	276	Q8TC27
KYLLPILGLFMAYYY	HSD11B1	6	P28845
LMYFIHYYLPEGLRR	HSD11B2	346	P80365
IAFYLLGMFIPYLYA	ERMP1	581	Q7Z2K6
PLLAIGFYLYRMNKY	CAPN14	416	A8MX76
IIGNLLYYRYMNPAI	IQGAP1	1186	P46940
AALGYFVPYVHLMKY	SLC16A2	331	P36021
KLIMEYLPYGSLRDY	JAK2	926	O60674
LGDQRYAPYKYMLRL	ITPR2	541	Q14571
LIVALMYPPYRYEAK	ANXA8	86	P13928
MLIIHNYLFLYIPYL	MOGAT1	41	Q96PD6
YFLYQLLRGLKYMHS	MAPK7	161	Q13164
FLPMYGLYEYLRKSV	LARGE1	566	O95461
PRVLDAMLPYLINYY	NFS1	71	Q9Y697
NYLVFLLMYLFPRQL	LETMD1	151	Q6P1Q0
MYAPKYLLKNYDRFH	MGAT3	481	Q09327
LPFMKYGDLHTYLLY	MERTK	671	Q12866
LLLNYGLYRKMEIYR	HDAC1	41	Q13547
LESLMFPLKYSYPYI	SBF2	241	Q86WG5
DPRDYKLLDMLQYYL	SMPDL3A	341	Q92484
FIPRLVYLYMYSKNG	ANO1	811	Q5XXA6
KFCLIYPYMRNGTLF	IRAK3	236	Q9Y616
LFYGSIIFMYLQPAK	OR2C3	251	Q8N628
KYAEYFLRPMLQYVC	IPO5	901	O00410
RAKGYPIDLYYLMDL	ITGB2	121	P05107
IPILYVKVYMYQLFR	GSK3A	216	P49840
YYCPELRQKAYMFIL	KLHL10	151	Q6JEL2
LIVALMYPPYRYEAK	ANXA8L1	86	Q5VT79
YSQMLLFPYGYTSKL	CPA3	306	P15088
PLGRDQYKEMYLFVY	DNASE1L2	91	Q92874
NFFVKVYGYMPLLYT	EXTL3	881	O43909
MPQLYIYIRLLGAYL	BMPR1A	1	P36894
FYIPFLLMVLAYYRI	HTR4	201	Q13639
RYFKGPELLVDYQMY	CSNK2A2	196	P19784
DLQPYKYAGYPMLIR	DNAJC13	1386	O75165
YKNSMGKSLPLFYIY	MANEAL	256	Q5VSG8
LLKYGMLLYQNYRIP	GRB10	396	Q13322
NLLLNYGLYRKMEIY	HDAC2	41	Q92769
YGMKAVLILYFLYFL	SLC15A2	61	Q16348
VYLGAYDRFLPYILM	SLC22A5	481	O76082
NKYMPGLLRAGYYDL	RYR2	1691	Q92736
YPKFKYALLAVMGAY	SEC11C	171	Q9BY50
YYYMLPMKVRALGLK	MRPL4	161	Q9BYD3
GYVYIPLAFLLMLYA	TMEM151B	111	Q8IW70
LLKIVGNLLYYRYMN	IQGAP2	1096	Q13576
MFYGTLLFIYLQPKS	OR8K1	256	Q8NGG5
KYGLLYYNALFMILP	SLC35D1	216	Q9NTN3
LILSLVYYFYNLMPL	TTC13	751	Q8NBP0
YMGLKLGPALKLCYY	SCML2	676	Q9UQR0
VGPMYSYVALYKFLP	STAC2	291	Q6ZMT1
YVGQPRFLLLFYAMY	PIEZO2	1901	Q9H5I5
RPYFCMLGAIYLLYI	TRPV6	366	Q9H1D0
SPFLCLYYPQMLYIK	PRAMEF10	261	O60809
ILLIFMLRSPYYKYE	TMEM97	156	Q5BJF2
RHYYFLGRMLGKALY	UBE3C	816	Q15386
GMALYKIVPKNPYYF	NAA25	136	Q14CX7