Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.06e-07	11	102	4	GO:0005388
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC11A2 SLC25A37 CCT8L2 P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	7.12e-07	465	102	13	GO:0046873
GeneOntologyMolecularFunction	ferrous iron transmembrane transporter activity	SLC11A2 SLC25A37 SLC25A28	2.56e-06	6	102	3	GO:0015093
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	P2RX4 TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.25e-05	151	102	7	GO:0015085
GeneOntologyMolecularFunction	ATP-dependent activity	CECR2 UPF1 FANCM HELQ CCT8L2 ATP11B CCT8 MACF1 CCT8L1P ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.47e-05	614	102	13	GO:0140657
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC11A2 SLC25A37 CCT8L2 P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.84e-05	627	102	13	GO:0022890
GeneOntologyMolecularFunction	iron ion transmembrane transporter activity	SLC11A2 SLC25A37 SLC25A28	2.07e-05	11	102	3	GO:0005381
GeneOntologyMolecularFunction	P-type transmembrane transporter activity	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.33e-05	36	102	4	GO:0140358
GeneOntologyMolecularFunction	P-type ion transporter activity	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.33e-05	36	102	4	GO:0015662
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC11A2 SLC25A37 CCT8L2 P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	3.34e-05	664	102	13	GO:0008324
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC11A2 SLC25A37 CCT8L2 ATP11B P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	5.03e-05	793	102	14	GO:0015075
GeneOntologyMolecularFunction	ATP hydrolysis activity	UPF1 FANCM HELQ ATP11B CCT8 MACF1 ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.68e-05	441	102	10	GO:0016887
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC11A2 SLC25A37 CCT8L2 P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.27e-04	758	102	13	GO:0015318
GeneOntologyMolecularFunction	calmodulin binding	SPHK1 TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.79e-04	230	102	7	GO:0005516
GeneOntologyMolecularFunction	ATPase-coupled monoatomic cation transmembrane transporter activity	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.85e-04	62	102	4	GO:0019829
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC11A2 MFSD2B SLC35F1 SLC25A37 CCT8L2 ATP11B P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	3.09e-04	1180	102	16	GO:0022857
GeneOntologyMolecularFunction	molybdopterin cofactor binding	AOX1 XDH	3.82e-04	6	102	2	GO:0043546
GeneOntologyMolecularFunction	transporter activity	SLC11A2 MFSD2B SLC35F1 SLC25A37 CCT8L2 ATP11B P2RX4 SLC28A2 TRPV6 SLC5A12 SLC25A28 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	8.10e-04	1289	102	16	GO:0005215
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC11A2 SLC28A2 SLC5A12 ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.98e-04	301	102	7	GO:0022853
GeneOntologyMolecularFunction	cargo receptor activity	STBD1 INSR APOBR STAB1	9.46e-04	85	102	4	GO:0038024
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	CCT8L2 CCT8 CCT8L1P	1.11e-03	40	102	3	GO:0140662
GeneOntologyMolecularFunction	transition metal ion transmembrane transporter activity	SLC11A2 SLC25A37 SLC25A28	1.47e-03	44	102	3	GO:0046915
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.37e-03	109	102	4	GO:0042626
GeneOntologyBiologicalProcess	regulation of cardiac conduction	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.27e-05	29	103	4	GO:1903779
GeneOntologyCellularComponent	chaperonin-containing T-complex	CCT8L2 CCT8 CCT8L1P	1.86e-05	11	103	3	GO:0005832
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.06e-10	4	101	4	IPR022141
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.06e-10	4	101	4	PF12424
Domain	P-type_ATPase_IIB	ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.06e-10	4	101	4	IPR006408
Domain	ATPase_P-typ_cyto_domN	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.19e-06	35	101	5	IPR023299
Domain	ATPase_P-typ_P_site	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.38e-06	36	101	5	IPR018303
Domain	P_typ_ATPase	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.38e-06	36	101	5	IPR001757
Domain	ATPASE_E1_E2	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.38e-06	36	101	5	PS00154
Domain	ATPase_P-typ_TM_dom	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.39e-06	16	101	4	IPR023298
Domain	-	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.39e-06	16	101	4	1.20.1110.10
Domain	ATPase_P-typ_transduc_dom_A	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.59e-06	37	101	5	IPR008250
Domain	E1-E2_ATPase	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.59e-06	37	101	5	PF00122
Domain	ATPase_P-typ_cation-transptr_C	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.82e-06	17	101	4	IPR006068
Domain	Cation_ATPase_C	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.82e-06	17	101	4	PF00689
Domain	Cation_ATPase_N	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.33e-06	18	101	4	PF00690
Domain	Cation_ATPase_N	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.33e-06	18	101	4	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.93e-06	19	101	4	IPR004014
Domain	-	AOX1 XDH	2.90e-05	2	101	2	3.30.365.10
Domain	AldOxase/xan_DH_Mopterin-bd	AOX1 XDH	2.90e-05	2	101	2	IPR008274
Domain	Ald_Xan_dh_C	AOX1 XDH	2.90e-05	2	101	2	PF01315
Domain	Fer2_2	AOX1 XDH	2.90e-05	2	101	2	PF01799
Domain	-	AOX1 XDH	2.90e-05	2	101	2	3.90.1170.50
Domain	CO_deh_flav_C	AOX1 XDH	2.90e-05	2	101	2	SM01092
Domain	CO_deh_flav_C	AOX1 XDH	2.90e-05	2	101	2	PF03450
Domain	Mopterin_DH_FAD-bd	AOX1 XDH	2.90e-05	2	101	2	IPR002346
Domain	Ald_Xan_dh_C	AOX1 XDH	2.90e-05	2	101	2	SM01008
Domain	2Fe-2S-bd	AOX1 XDH	2.90e-05	2	101	2	IPR002888
Domain	FAD_binding_5	AOX1 XDH	2.90e-05	2	101	2	PF00941
Domain	Ald_Oxase/Xan_DH_a/b	AOX1 XDH	2.90e-05	2	101	2	IPR000674
Domain	TRPV5/TRPV6	TRPV6 TRPV5	2.90e-05	2	101	2	IPR008344
Domain	Ald_Xan_dh_C2	AOX1 XDH	2.90e-05	2	101	2	PF02738
Domain	ATP2B1/4	ATP2B1 ATP2B4	2.90e-05	2	101	2	IPR030319
Domain	CO_DH_flav_C	AOX1 XDH	2.90e-05	2	101	2	IPR005107
Domain	Ald_Oxase/xanthine_DH	AOX1 XDH	2.90e-05	2	101	2	IPR016208
Domain	-	AOX1 XDH	2.90e-05	2	101	2	1.10.150.120
Domain	HAD-like_dom	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	6.87e-05	79	101	5	IPR023214
Domain	MOLYBDOPTERIN_EUK	AOX1 XDH	8.66e-05	3	101	2	PS00559
Domain	OxRdtase_Mopterin-bd_dom	AOX1 XDH	8.66e-05	3	101	2	IPR000572
Domain	OxRdtase_Mopterin_BS	AOX1 XDH	8.66e-05	3	101	2	IPR022407
Domain	CRIB	WAS CDC42BPB TNK2	1.64e-04	20	101	3	PS50108
Domain	CRIB_dom	WAS CDC42BPB TNK2	1.90e-04	21	101	3	IPR000095
Domain	2Fe2S_fd_BS	AOX1 XDH	2.86e-04	5	101	2	IPR006058
Domain	-	AOX1 XDH	2.86e-04	5	101	2	3.30.43.10
Domain	FAD-bd_2_sub1	AOX1 XDH	2.86e-04	5	101	2	IPR016167
Domain	2FE2S_FER_1	AOX1 XDH	2.86e-04	5	101	2	PS00197
Domain	2FE2S_FER_2	AOX1 XDH	4.28e-04	6	101	2	PS51085
Domain	-	AOX1 XDH	4.28e-04	6	101	2	3.30.465.10
Domain	2Fe-2S_ferredoxin-type	AOX1 XDH	4.28e-04	6	101	2	IPR001041
Domain	Fer2	AOX1 XDH	4.28e-04	6	101	2	PF00111
Domain	FAD_PCMH	AOX1 XDH	4.28e-04	6	101	2	PS51387
Domain	CO_DH_flavot_FAD-bd_sub2	AOX1 XDH	4.28e-04	6	101	2	IPR016169
Domain	FAD-bd_2	AOX1 XDH	4.28e-04	6	101	2	IPR016166
Domain	-	ATP11B ATP2B1 ATP2B2	6.79e-04	32	101	3	3.40.1110.10
Domain	-	ATP11B ATP2B1 ATP2B2	6.79e-04	32	101	3	2.70.150.10
Domain	Helicase/UvrB_N	UPF1 FANCM	7.94e-04	8	101	2	IPR006935
Domain	ResIII	UPF1 FANCM	7.94e-04	8	101	2	PF04851
Domain	TCP1_1	CCT8L2 CCT8	1.27e-03	10	101	2	PS00750
Domain	TCP1_2	CCT8L2 CCT8	1.27e-03	10	101	2	PS00751
Domain	TCP1_3	CCT8L2 CCT8	1.27e-03	10	101	2	PS00995
Domain	Hydrolase_3	ATP2B2 ATP2B3	1.27e-03	10	101	2	PF08282
Domain	Chaperone_TCP-1	CCT8L2 CCT8	1.27e-03	10	101	2	IPR017998
Domain	TRP_channel	TRPV6 TRPV5	1.54e-03	11	101	2	IPR004729
Domain	-	CCT8L2 CCT8	1.54e-03	11	101	2	3.30.260.10
Domain	TCP-1-like_intermed	CCT8L2 CCT8	1.54e-03	11	101	2	IPR027410
Domain	-	WAS CDC42BPB	1.84e-03	12	101	2	3.90.810.10
Domain	-	HSDL2 ACLY ME3 GFOD2 VAT1	2.25e-03	169	101	5	3.40.50.720
Domain	NAD(P)-bd_dom	HSDL2 ACLY ME3 GFOD2 VAT1	2.49e-03	173	101	5	IPR016040
Domain	-	AOX1 XDH	2.53e-03	14	101	2	3.10.20.30
Domain	GROEL-like_equatorial	CCT8L2 CCT8	2.53e-03	14	101	2	IPR027413
Domain	Beta-grasp_dom	AOX1 XDH	2.53e-03	14	101	2	IPR012675
Domain	-	CCT8L2 CCT8	2.53e-03	14	101	2	1.10.560.10
Domain	GroEL-like_apical_dom	CCT8L2 CCT8	2.90e-03	15	101	2	IPR027409
Domain	Cpn60/TCP-1	CCT8L2 CCT8	2.90e-03	15	101	2	IPR002423
Domain	Cpn60_TCP1	CCT8L2 CCT8	2.90e-03	15	101	2	PF00118
Domain	-	CCT8L2 CCT8	2.90e-03	15	101	2	3.50.7.10
Domain	PBD	WAS CDC42BPB	3.31e-03	16	101	2	SM00285
Domain	PBD	WAS CDC42BPB	3.73e-03	17	101	2	PF00786
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	P2RX4 ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.93e-07	27	76	5	MM15053
Pathway	REACTOME_PLATELET_CALCIUM_HOMEOSTASIS	P2RX4 ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.56e-07	28	76	5	M924
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.74e-07	12	76	4	M27326
Pathway	REACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.49e-07	14	76	4	MM15052
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.12e-05	55	76	5	M971
Pathway	REACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.34e-05	57	76	5	MM15643
Pathway	WP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION	ATP2B1 ATP2B2 ATP2B3 ATP2B4	4.03e-05	36	76	4	M39831
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP11B TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	4.44e-05	176	76	7	MM15718
Pathway	REACTOME_PLATELET_HOMEOSTASIS	P2RX4 ATP2B1 ATP2B2 ATP2B3 ATP2B4	5.46e-05	76	76	5	MM15051
Pathway	REACTOME_ION_CHANNEL_TRANSPORT	ATP11B TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	5.69e-05	183	76	7	M997
Pathway	REACTOME_PLATELET_HOMEOSTASIS	P2RX4 ATP2B1 ATP2B2 ATP2B3 ATP2B4	9.88e-05	86	76	5	M916
Pathway	REACTOME_ION_HOMEOSTASIS	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.01e-04	54	76	4	M27460
Pathway	REACTOME_ION_HOMEOSTASIS	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.01e-04	54	76	4	MM15202
Pathway	KEGG_CALCIUM_SIGNALING_PATHWAY	P2RX4 SPHK1 ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.92e-04	178	76	6	M2890
Pathway	WP_MOLYBDENUM_COFACTOR_MOCO_BIOSYNTHESIS	AOX1 XDH	5.92e-04	7	76	2	M39799
Pathway	WP_EFFECTS_OF_NITRIC_OXIDE	AOX1 XDH	7.86e-04	8	76	2	M39677
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC11A2 APOBR ATP11B SLC28A2 TRPV6 SLC5A12 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.01e-03	681	76	11	MM14985
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	12209837
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	12784250
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	15101689
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	8245032
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	8634322
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	11152753
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.25e-11	4	103	4	10434059
Pubmed	Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.62e-10	5	103	4	17938178
Pubmed	Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.08e-09	6	103	4	12767889
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.49e-09	38	103	6	30786075
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2B1 ATP2B2 ATP2B3 ATP2B4	5.03e-09	8	103	4	10951186
Pubmed	Biology, structure and mechanism of P-type ATPases.	ATP11B ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.32e-08	29	103	5	15071553
Pubmed	Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.	XDH SLC25A37 SLC25A28	2.52e-08	3	103	3	21310927
Pubmed	Increased maternofetal calcium flux in parathyroid hormone-related protein-null mice.	TRPV6 ATP2B1 ATP2B4	2.51e-07	5	103	3	18258656
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	STBD1 HSDL2 RPS12 SHMT1 SRPK2 UPF1 PFKM ECSIT CDC42BPB PRPF40A MTR MACF1 NUDC ATP2B1 ATP2B4 TBL2 VCL SYNCRIP	3.57e-07	1487	103	18	33957083
Pubmed	Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.	ATP2B1 ATP2B2 ATP2B4	5.01e-07	6	103	3	12763866
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	ACLY RPS12 PEPD ACOT7 UPF1 PFKM PRPF40A LENG8 CCT8 MACF1 NUDC CPSF3 PKN3 VCL	6.92e-07	934	103	14	33916271
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	HSDL2 ACLY RPS12 SHMT1 UPF1 PFKM HIGD1A KLHL9 MTR CCT8 NUDC COPS5 CPSF3 TBL2 SYNCRIP VAT1	9.00e-07	1257	103	16	37317656
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ACLY ACOT7 SRPK2 UPF1 PFKM CDC42BPB PRPF40A CCT8 PACS2 MACF1 ATP2B1 ATP2B2 ATP2B3 ATP2B4 CNTN2 VCL SYNCRIP	1.02e-06	1431	103	17	37142655
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	UPF1 PFKM PRPF40A STAB1 CCT8 MACF1 GEMIN6 NUDC COPS5 CPSF3 SYNCRIP	1.30e-06	582	103	11	20467437
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	HSDL2 ACLY RPS12 PEPD UPF1 PFKM PRPF40A MTR CCT8 NUDC ATP2B1 ATP2B3 CPSF3 VCL SYNCRIP VAT1	4.52e-06	1425	103	16	30948266
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	ACLY RPS12 PEPD ACOT7 SHMT1 GMPR2 PFKM OXCT1 MTR CCT8 MACF1 NUDC COPS5 VCL SYNCRIP VAT1	5.87e-06	1455	103	16	22863883
Pubmed	Identification of pp68 as the Tyrosine-phosphorylated Form of SYNCRIP/NSAP1. A cytoplasmic RNA-binding protein.	INSR SYNCRIP	8.69e-06	2	103	2	11994298
Pubmed	Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.	TRPV6 TRPV5	8.69e-06	2	103	2	20178461
Pubmed	The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.	TRPV6 TRPV5	8.69e-06	2	103	2	22354706
Pubmed	Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.	TRPV6 TRPV5	8.69e-06	2	103	2	16564089
Pubmed	The mitochondrial metal transporters mitoferrin1 and mitoferrin2 are required for liver regeneration and cell proliferation in mice.	SLC25A37 SLC25A28	8.69e-06	2	103	2	32518166
Pubmed	Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.	TRPV6 TRPV5	8.69e-06	2	103	2	19295174
Pubmed	Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity.	TRPV6 TRPV5	8.69e-06	2	103	2	23968883
Pubmed	Expression of calcium channels along the differentiation of cultured trophoblast cells from human term placenta.	TRPV6 TRPV5	8.69e-06	2	103	2	12390878
Pubmed	Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta.	ATP2B1 ATP2B4	8.69e-06	2	103	2	18657858
Pubmed	Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis.	SLC25A37 SLC25A28	8.69e-06	2	103	2	21248200
Pubmed	Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.	TRPV6 TRPV5	8.69e-06	2	103	2	12574114
Pubmed	Coexpression and estrogen-mediated regulation of TRPV6 and PMCA1 in the human endometrium during the menstrual cycle.	TRPV6 ATP2B1	8.69e-06	2	103	2	21400627
Pubmed	Structural conservation of the genes encoding CaT1, CaT2, and related cation channels.	TRPV6 TRPV5	8.69e-06	2	103	2	11549322
Pubmed	[TRPV5 and TRPV6 calcium channels in human T cells].	TRPV6 TRPV5	8.69e-06	2	103	2	19140341
Pubmed	TRPV5 and TRPV6 are expressed in placenta and bone tissues during pregnancy in mice.	TRPV6 TRPV5	8.69e-06	2	103	2	30916584
Pubmed	Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.	TRPV6 TRPV5	8.69e-06	2	103	2	16565876
Pubmed	Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2.	SLC25A37 SLC25A28	8.69e-06	2	103	2	19075006
Pubmed	The influence of membrane lipid structure on plasma membrane Ca2+ -ATPase activity.	ATP2B1 ATP2B4	8.69e-06	2	103	2	16412504
Pubmed	Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.	ATP2B1 ATP2B4	8.69e-06	2	103	2	16956963
Pubmed	Localization of two genes encoding plasma membrane Ca2+ ATPases isoforms 2 (ATP2B2) and 3 (ATP2B3) to human chromosomes 3p26-->p25 and Xq28, respectively.	ATP2B2 ATP2B3	8.69e-06	2	103	2	8187550
Pubmed	Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6.	TRPV6 TRPV5	8.69e-06	2	103	2	16705151
Pubmed	Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23.	ATP2B1 ATP2B4	8.69e-06	2	103	2	1674727
Pubmed	Role of polymorphic variants of MTR gene A2756G and SHMT1 gene C1420T in the development of prostatic cancer in residents of the Western Siberian Region of Russia.	SHMT1 MTR	8.69e-06	2	103	2	22803112
Pubmed	Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.	TRPV6 TRPV5	8.69e-06	2	103	2	20405023
Pubmed	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.	ATP2B2 ATP2B4	8.69e-06	2	103	2	1313367
Pubmed	Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.	ATP2B3 ATP2B4	8.69e-06	2	103	2	1531651
Pubmed	A single amino acid mutation results in a rapid inactivation of epithelial calcium channels.	TRPV6 TRPV5	8.69e-06	2	103	2	11846401
Pubmed	First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.	TRPV6 TRPV5	8.69e-06	2	103	2	25164318
Pubmed	Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.	ATP2B1 ATP2B4	8.69e-06	2	103	2	15178683
Pubmed	Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.	TRPV6 TRPV5	8.69e-06	2	103	2	24761864
Pubmed	Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinase.	WAS TNK2	8.69e-06	2	103	2	16257963
Pubmed	Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.	ATP2B2 ATP2B4	8.69e-06	2	103	2	22252018
Pubmed	Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.	TRPV6 TRPV5	8.69e-06	2	103	2	15123711
Pubmed	Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.	TRPV6 TRPV5	8.69e-06	2	103	2	12077127
Pubmed	Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.	ATP2B1 ATP2B4	8.69e-06	2	103	2	16291816
Pubmed	Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.	ATP2B2 ATP2B4	8.69e-06	2	103	2	25690014
Pubmed	Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.	ATP2B1 ATP2B4	8.69e-06	2	103	2	10748016
Pubmed	Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.	ATP2B1 ATP2B4	8.69e-06	2	103	2	26116539
Pubmed	Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.	TRPV6 TRPV5	8.69e-06	2	103	2	11719848
Pubmed	Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.	TRPV6 TRPV5	8.69e-06	2	103	2	17233615
Pubmed	Mitoferrin is essential for erythroid iron assimilation.	SLC25A37 SLC25A28	8.69e-06	2	103	2	16511496
Pubmed	Aminoacylase 1 is a sphingosine kinase 1-interacting protein.	ACY1 SPHK1	8.69e-06	2	103	2	15196915
Pubmed	[The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].	TRPV6 TRPV5	8.69e-06	2	103	2	24592736
Pubmed	Nitrite reductase activity of rat and human xanthine oxidase, xanthine dehydrogenase, and aldehyde oxidase: evaluation of their contribution to NO formation in vivo.	AOX1 XDH	8.69e-06	2	103	2	25537183
Pubmed	Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival.	ATP2B1 ATP2B4	8.69e-06	2	103	2	23266958
Pubmed	Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.	ATP2B2 ATP2B4	8.69e-06	2	103	2	16216224
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	WAS ACLY SHMT1 SRPK2 UPF1 PRPF40A CCT8 NUDC CPSF3 SYNCRIP VAT1	9.11e-06	714	103	11	28302793
Pubmed	140 mouse brain proteins identified by Ca2+-calmodulin affinity chromatography and tandem mass spectrometry.	PFKM NUDC ATP2B1 ATP2B3 ATP2B4 VAT1	9.49e-06	163	103	6	16512683
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	CFAP47 ACLY RPS12 UPF1 PFKM CCT8 NUDC VCL SYNCRIP	1.69e-05	494	103	9	26831064
Pubmed	Characterization of the zinc-induced Shank3 interactome of mouse synaptosome.	ACLY ACOT7 ME3 CCT8 ATP2B2	1.89e-05	109	103	5	29111324
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	ACLY INSR RPS12 ACOT7 SRPK2 UPF1 PFKM PRPF40A CCT8 OXSM NUDC TBL2 VCL SYNCRIP	1.90e-05	1247	103	14	27684187
Pubmed	Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.	SLC25A37 SLC25A28	2.60e-05	3	103	2	19805291
Pubmed	A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.	TRPV6 TRPV5	2.60e-05	3	103	2	27291418
Pubmed	Plasma Membrane Calcium ATPase-Neuroplastin Complexes Are Selectively Stabilized in GM1-Containing Lipid Rafts.	ATP2B1 ATP2B2	2.60e-05	3	103	2	34948386
Pubmed	Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.	TRPV6 TRPV5	2.60e-05	3	103	2	16763551
Pubmed	Polymorphisms in methionine synthase, methionine synthase reductase and serine hydroxymethyltransferase, folate and alcohol intake, and colon cancer risk.	SHMT1 MTR	2.60e-05	3	103	2	19776626
Pubmed	A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.	ATP2B1 ATP2B4	2.60e-05	3	103	2	28827723
Pubmed	Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.	TRPV6 TRPV5	2.60e-05	3	103	2	16354700
Pubmed	Risk of colorectal cancer associated with the C677T polymorphism in 5,10-methylenetetrahydrofolate reductase in Portuguese patients depends on the intake of methyl-donor nutrients.	SHMT1 MTR	2.60e-05	3	103	2	18996879
Pubmed	Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice.	ATP2B1 ATP2B4	2.60e-05	3	103	2	33098669
Pubmed	Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.	TRPV6 TRPV5	2.60e-05	3	103	2	17200157
Pubmed	Breast cancer risk associated with multigenotypic polymorphisms in folate-metabolizing genes: a nested case-control study in Taiwan.	SHMT1 MTR	2.60e-05	3	103	2	17595805
Pubmed	Sphingosine-1-phosphate suppresses GLUT activity through PP2A and counteracts hyperglycemia in diabetic red blood cells.	MFSD2B SPHK1	2.60e-05	3	103	2	38097610
Pubmed	Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine.	AOX1 XDH	2.60e-05	3	103	2	22495427
Pubmed	A dock and coalesce mechanism driven by hydrophobic interactions governs Cdc42 binding with its effector protein ACK.	WAS TNK2	2.60e-05	3	103	2	28539360
Pubmed	The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.	ATP2B2 ATP2B4	2.60e-05	3	103	2	17689535
Pubmed	Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells.	ATP2B2 ATP2B4	2.60e-05	3	103	2	20211863
Pubmed	Trafficking of presynaptic PMCA signaling complexes in mouse photoreceptors requires Cav1.4 α1 subunits.	ATP2B1 ATP2B2	2.60e-05	3	103	2	22183401
Pubmed	Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.	TRPV6 TRPV5	2.60e-05	3	103	2	19922080
Pubmed	Protein kinase C phosphorylates the carboxyl terminus of the plasma membrane Ca(2+)-ATPase from human erythrocytes.	ATP2B1 ATP2B2	2.60e-05	3	103	2	1827443
Pubmed	Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.	TRPV6 TRPV5	2.60e-05	3	103	2	16380433
Pubmed	Plasma membrane Ca2+ ATPase isoform 2b interacts preferentially with Na+/H+ exchanger regulatory factor 2 in apical plasma membranes.	ATP2B1 ATP2B2	2.60e-05	3	103	2	11786550
Pubmed	Novel pharmacogenetic markers for treatment outcome in azathioprine-treated inflammatory bowel disease.	AOX1 XDH	2.60e-05	3	103	2	19500084
Pubmed	CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.	ATP2B1 ATP2B4	2.60e-05	3	103	2	15133509
Interaction	C17orf78 interactions	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.74e-07	12	100	4	int:C17orf78
Interaction	HSD17B6 interactions	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.47e-07	15	100	4	int:HSD17B6
Interaction	CYP2B6 interactions	ATP2B2 ATP2B3 ATP2B4	6.52e-06	8	100	3	int:CYP2B6
Interaction	LILRB4 interactions	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.07e-05	28	100	4	int:LILRB4
Interaction	C5AR1 interactions	WAS SLC35F1 ECSIT ATP2B2 ATP2B3 ATP2B4 YIPF3	1.17e-05	154	100	7	int:C5AR1
Interaction	HCRTR2 interactions	NT5C1A ATP2B2 ATP2B3 ATP2B4	4.11e-05	39	100	4	int:HCRTR2
Interaction	NRAS interactions	HSDL2 ACLY FRMD7 INSR PFKM CDC42BPB SLITRK2 MTR MACF1 ATP2B1 ATP2B4 TBL2 VAT1	4.17e-05	699	100	13	int:NRAS
GeneFamily	ATPases Ca2+ transporting	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.27e-08	9	59	4	1209
GeneFamily	X-linked mental retardation\|RNA helicases	FANCM HELQ	5.65e-04	11	59	2	1168
GeneFamily	Solute carriers	SLC11A2 SLC35F1 SLC25A37 SLC28A2 SLC5A12 SLC25A28	1.78e-03	395	59	6	752
Coexpression	GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP	DIP2B PEPD CDC42BPB PACS2 OXSM ATP2B1 TTC38	1.45e-05	200	103	7	M6613
Coexpression	GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP	ADAM19 ACOT7 XDH POLR1H TNK2 SLC25A28 VCL	1.45e-05	200	103	7	M8505
Coexpression	AIZARANI_LIVER_C20_LSECS_3	FNDC3B INSR ITGA9 CDC42BPB SLC25A37 STAB1 MACF1 VCL	2.21e-05	295	103	8	M39121
ToppCell	droplet-Marrow-BM-30m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 MFSD2B ISG20 PFKM SLC25A37 SPHK1	5.02e-06	188	103	6	f1a9d8ea174a4bef0fae8188e3bd96b7ac1a39bb
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSDL2 ACOT7 SHMT1 STAB1 SLC28A2 VAT1	5.02e-06	188	103	6	1b349618f77260564486586b7f5a47a77d12859c
ToppCell	droplet-Marrow-nan-24m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 MFSD2B ISG20 PFKM SLC25A37 SPHK1	5.17e-06	189	103	6	98ace332c3c046694c6ade47de8c8bf57ec51271
ToppCell	droplet-Marrow-BM-1m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC11A2 MFSD2B ISG20 PFKM SLC25A37 SPHK1	5.50e-06	191	103	6	d78d4fbb0b8317dbf14e32182466a432abef3e93
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DIP2B FNDC3B INSR SRPK2 MACF1 SLC5A12	5.66e-06	192	103	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	UGT3A1 AOX1 PEPD ACOT7 SLC5A12 TTC38	6.56e-06	197	103	6	9b038dac4d4d306aa40ec07d79374c4fe9c604a6
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FNDC3B ADAM19 ZNF407 APOBR STAB1 ATP2B1	6.95e-06	199	103	6	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEURL2 MFSD2B ISG20 SLC25A37 ADAMDEC1	3.33e-05	158	103	5	9fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEURL2 MFSD2B ISG20 SLC25A37 ADAMDEC1	3.33e-05	158	103	5	0edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ME3 LIM2 UMODL1 TTC38 VCL	3.33e-05	158	103	5	1bf692f1e85f677cd62805437b7a59cfaf3b0449
ToppCell	E17.5-Hematopoietic-Erythroid-enucleate_erythrocyte\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MFSD2B ISG20 SLC25A37 ATP2B3	3.95e-05	82	103	4	8917c6fd4a6e3cb7a3a2af489ccc3fdc55c26698
ToppCell	E17.5-Hematopoietic-Erythroid\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MFSD2B ISG20 SLC25A37 ATP2B3	3.95e-05	82	103	4	e0b12b9fb3cd56902b068dc0d921241481aa70a9
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD2B ISG20 RFX2 SLC25A37 SPHK1	4.46e-05	168	103	5	17fb9426eeea407b26fb895b8397faca95b7552d
ToppCell	facs-Marrow-B-cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD2B ISG20 RFX2 SLC25A37 SPHK1	4.46e-05	168	103	5	a61b39884851384cffd430079040546d125b2b40
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	AOX1 RPS12 ACY1 UMODL1 ATP2B2	4.71e-05	170	103	5	a50e558d0b38100ccbdccb90647fe93e85bffd86
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FNDC3B ACY1 SLC25A37 PTPRN2 ATP2B4	4.85e-05	171	103	5	2b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FNDC3B ACY1 SLC25A37 PTPRN2 ATP2B4	4.85e-05	171	103	5	dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCell	356C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	NEURL2 ITGA9 FANCM STAB1 VAT1	5.41e-05	175	103	5	7de1023161233b64f11e130881c742f4cf2bff65
ToppCell	droplet-Spleen-nan-24m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD2B ISG20 SLC25A37 SPHK1 ATP2B4	6.02e-05	179	103	5	f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCell	droplet-Spleen-nan-24m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFSD2B ISG20 SLC25A37 SPHK1 ATP2B4	6.02e-05	179	103	5	01e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell	HSPCs-Erythroblasts\|World / Lineage and Cell class	MFSD2B ISG20 PFKM SLC25A37 SPHK1	6.34e-05	181	103	5	ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCell	B_cells-ISG-high_B_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ADAM19 ISG20 WDFY4 SLC25A28 DOP1A	6.68e-05	183	103	5	dc2b00e920efa1dcc2a6265cd1024e3249c9974f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INSR AOX1 ACY1 SLC5A12 TTC38	6.68e-05	183	103	5	85446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FNDC3B SLC11A2 SLC25A37 SPHK1 ATP2B1	6.86e-05	184	103	5	857ca1fc4de07b300839b22924211dc624453841
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	INSR ISG20 RFX2 CDC42BPB SLC25A37	7.04e-05	185	103	5	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSDL2 ACOT7 SHMT1 SLC28A2 VAT1	7.04e-05	185	103	5	3f1aa91efae2d00320d126087cce1431ad5f26ea
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSDL2 ACOT7 SHMT1 SLC28A2 VAT1	7.22e-05	186	103	5	744bf39af2fb5a7454477174d7755a6d78cd279f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INSR AOX1 PEPD SLC5A12 TTC38	7.22e-05	186	103	5	8287146f0ba415ea04475588117d4668ae00f75c
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSDL2 SHMT1 STAB1 SLC28A2 VAT1	7.40e-05	187	103	5	81d7c3802667190f11e9dcd797ee7b88aadbb8de
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INSR AOX1 PEPD SLC5A12 TTC38	7.40e-05	187	103	5	71eb26ebf60cb0848e5bf1cd01edccda621aecd8
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	UGT3A1 AOX1 PEPD SLC5A12 NUDC	7.40e-05	187	103	5	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-cDC1\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	WAS ISG20 ERICH5 APOBR WDFY4	8.18e-05	191	103	5	9774d423e448ec2d415261e4ad386a81558129b3
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	ADAM19 INSR OXCT1 ATP2B4 VCL	8.59e-05	193	103	5	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	Control-Myeloid-Macrophage\|World / Disease state, Lineage and Cell class	FNDC3B SLC25A37 STAB1 SPHK1 ATP2B1	8.80e-05	194	103	5	c35bf04d5e7450cb6679a036fcabb1b28f409f29
ToppCell	CV-Severe-6\|CV / Virus stimulation, Condition and Cluster	WAS ISG20 LIM2 ATP2B4 VCL	9.01e-05	195	103	5	69095c6ce2a7e763afa543c10d5710e0c3dda769
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC25A37 STAB1 ADAMDEC1 SPHK1 ATP2B1	9.23e-05	196	103	5	c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCell	10x5'-Lung-Myeloid_Mac-Intermediate_macrophages\|Lung / Manually curated celltypes from each tissue	FNDC3B SLC25A37 STAB1 P2RX4 SPHK1	9.23e-05	196	103	5	fede2c605f7581ce2ea7a284cffffa1a3970d811
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC25A37 STAB1 ADAMDEC1 SPHK1 ATP2B1	9.23e-05	196	103	5	64c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FNDC3B ADAM19 APOBR STAB1 ATP2B1	9.23e-05	196	103	5	a44a648bf209ce037bfc7b3adfcb220aab60728c
ToppCell	distal-1-Hematologic-Plasma\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ADAM19 INSR ISG20 TXNDC15 ADAMDEC1	9.46e-05	197	103	5	f5499bfa9dbc111f12563b7006bc45c2423ad0cd
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FNDC3B ADAM19 SLC25A37 SPHK1 ATP2B1	9.46e-05	197	103	5	59aa4a31674125ae422450aee45db3ced5c405d3
ToppCell	Control-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	FNDC3B AOX1 RFX2 SLC25A37 NOVA1	9.46e-05	197	103	5	64cc5f61c88e9560b0f8f6f3151255dffb5c3d66
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AOX1 PEPD ACOT7 SLC5A12 TTC38	9.69e-05	198	103	5	72733b6149b797ac11cc108bc80428b77fbbba78
ToppCell	BAL-Severe\|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ISG20 SLC25A37 STAB1 SPHK1 MACF1	9.69e-05	198	103	5	454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	AOX1 PEPD ACOT7 SLC5A12 TTC38	9.69e-05	198	103	5	f23559ce6072e3c323f6791ff95269271b0f7ff1
ToppCell	moderate-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	SLC11A2 STAB1 P2RX4 SPHK1 MACF1	9.92e-05	199	103	5	3895e367a33ac0316f96a64c07574de99684f4b7
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-Trm_Th1/Th17\|GI_small-bowel / Manually curated celltypes from each tissue	ADAM19 RPS12 ISG20 ATP2B1 ATP2B4	9.92e-05	199	103	5	508a6efc11b1b45899a968888865731088cac668
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	UGT3A1 PEPD ACOT7 SLC5A12 TTC38	9.92e-05	199	103	5	4bde35e5df019189433d65d415e29a0c1145ac66
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	WAS APOBR WDFY4 STAB1 ADAMDEC1	9.92e-05	199	103	5	c72279fa3ca2ebc42a1446507673df154b8033c7
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-OPC_related\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SLC35F1 SLITRK2 TNK2 ATP2B4 NOVA1	1.02e-04	200	103	5	439265194cb08d1373296bf8684cc31294cecb20
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-OPC_related-OPC\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	SLC35F1 SLITRK2 TNK2 ATP2B4 NOVA1	1.02e-04	200	103	5	0450a79c5fae5ccacdb990ae674e4734ef0c3691
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	UGT3A1 AOX1 PEPD ACOT7 SLC5A12	1.02e-04	200	103	5	825aad08431dd6b54aa636ace6efc821dfaf8014
Drug	acetate	STBD1 ACLY PEPD XDH PFKM ACY1 ME3 OXCT1 PACS2 TNK2 TRPV6 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.34e-09	599	102	17	CID000000175
Drug	1sqc	ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.81e-08	10	102	4	CID000444279
Drug	2,5-dimethylquinone	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.22e-07	11	102	4	CID000008718
Drug	1vyq	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.83e-07	12	102	4	CID004369390
Drug	Ro 46861	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.83e-07	12	102	4	CID000003128
Drug	AC1MMLID	SLC11A2 TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	1.89e-07	92	102	7	CID000013245
Drug	AC1NSKPI	P2RX4 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.10e-07	57	102	6	CID005311482
Drug	8-hydroxycoumarin	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.63e-07	13	102	4	CID000122783
Drug	acetyl phosphate	PFKM OXCT1 TNK2 ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.91e-07	98	102	7	CID000000186
Drug	p-hydroxyhippuric acid	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.67e-07	14	102	4	CID000151012
Drug	mag-fura-2	ATP2B1 ATP2B2 ATP2B3 ATP2B4 CNTN2	6.36e-07	37	102	5	CID000123839
Drug	caged ATP	ITGA9 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.24e-07	70	102	6	CID000123806
Drug	AC1L88YH	ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.64e-07	17	102	4	CID000374551
Drug	phosphocreatine disodium	PFKM ME3 SLC28A2 ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.61e-06	126	102	7	CID000000587
Drug	2brh	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.14e-06	21	102	4	CID000848641
Drug	AC1L1G0K	ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	2.67e-06	49	102	5	CID000003473
Drug	AC1L25Y6	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.15e-06	23	102	4	CID000015465
Drug	lanthanum chloride hydrate	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.15e-06	23	102	4	CID000165791
Drug	C13932	PFKM PRPF40A TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	4.15e-06	206	102	8	CID000168297
Drug	cyhexatin	ATP2B1 ATP2B2 ATP2B3 ATP2B4	4.47e-06	25	102	4	CID005364545
Drug	Bay K 8644	TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5 PKN3	5.12e-06	150	102	7	CID000002303
Drug	dodecyl ether	ATP2B1 ATP2B2 ATP2B3 ATP2B4	5.26e-06	26	102	4	CID000020667
Drug	octaethylene glycol	ATP2B1 ATP2B2 ATP2B3 ATP2B4	8.27e-06	29	102	4	CID000078798
Drug	tBuBHQ	FRMD7 ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.46e-05	69	102	5	CID000002374
Drug	trifluoperazine	XDH PFKM ITGA9 ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3 VCL	1.54e-05	324	102	9	CID000005566
Drug	poly I	XDH GMPR2 PFKM POLR1H STAB1 NT5C1A P2RX4 PKN3	1.70e-05	250	102	8	CID000000797
Drug	fluorescamine	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.79e-05	35	102	4	CID000037927
Drug	fluo-3	P2RX4 ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3	1.85e-05	122	102	6	CID000104978
Drug	sodium	PEPD UPF1 ATP11B P2RX4 SLC28A2 MTR TRPV6 OXSM SLC5A12 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5 PKN3	1.97e-05	944	102	15	CID000000923
Drug	5-hydroxypyrazinoic acid	AOX1 XDH	1.99e-05	2	102	2	CID000161825
Drug	caloxin 1b1	ATP2B1 ATP2B4	1.99e-05	2	102	2	ctd:C510327
Drug	5-hydroxypyrazinamide	AOX1 XDH	1.99e-05	2	102	2	CID000151823
Drug	succinate	SHMT1 PFKM ME3 OXCT1 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.20e-05	339	102	9	CID000001110
Drug	gramicidin s	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.24e-05	37	102	4	CID000073357
Drug	2-aminoethyl diphenylborinate	P2RX4 TRPV6 ATP2B1 ATP2B2 TRPV5 PKN3	2.33e-05	127	102	6	CID000001598
Drug	K 2S	WAS XDH OXSM	2.42e-05	13	102	3	CID000014800
Drug	AC1L1IZE	INSR P2RX4 ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.77e-05	131	102	6	CID000004799
Drug	carbidine	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.07e-05	40	102	4	CID000065684
Drug	ronidazole	AOX1 XDH GMPR2	3.07e-05	14	102	3	CID000005094
Drug	AC1L970B	ACLY OXCT1 OXSM	3.07e-05	14	102	3	CID000439266
Drug	lanthanum	TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5	3.42e-05	136	102	6	CID000023926
Drug	C12E8	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.73e-05	42	102	4	CID000123921
Drug	XeC compound	TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.81e-05	84	102	5	CID000005701
Drug	linopirdine	ATP2B1 ATP2B2 ATP2B3 ATP2B4	4.10e-05	43	102	4	CID000003932
Drug	agelasine B	ATP2B1 ATP2B2 ATP2B3 ATP2B4	5.36e-05	46	102	4	CID006439899
Drug	dithionite	AOX1 XDH ATP2B1 ATP2B2 ATP2B3 ATP2B4	5.92e-05	150	102	6	CID000001086
Drug	2-hydroxypurine	AOX1 XDH	5.94e-05	3	102	2	CID000075323
Drug	AC1Q68Z5	ACLY SHMT1 GMPR2 PFKM ACY1 ME3 OXCT1 TNK2 OXSM	6.03e-05	386	102	9	CID000000181
Drug	hypoxanthine	AOX1 SHMT1 XDH GMPR2 PFKM NT5C1A SLC28A2	6.07e-05	220	102	7	CID000000790
Drug	nitrous oxide	MTR ATP2B1 ATP2B2 ATP2B3 ATP2B4	7.23e-05	96	102	5	CID000000948
Drug	nsc25485	NT5C1A MTR OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3	8.17e-05	312	102	8	CID000004605
Drug	indo-1	ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3	8.38e-05	99	102	5	CID000105060
Drug	1,4-dibromobutane	ATP2B1 ATP2B2 ATP2B3 ATP2B4	9.39e-05	53	102	4	CID000008056
Drug	succinyl-coenzyme A	ACLY ACY1 ME3 OXCT1 MTR OXSM	1.04e-04	166	102	6	CID000001111
Drug	AC1L212F	AOX1 XDH	1.19e-04	4	102	2	CID000013118
Drug	m-tolualdehyde	AOX1 OXSM	1.19e-04	4	102	2	CID000012105
Drug	AC1L3UXH	AOX1 XDH	1.19e-04	4	102	2	CID000065446
Drug	picrolonic acid	AOX1 XDH	1.19e-04	4	102	2	CID000068369
Drug	chlorex	ACLY VCL	1.19e-04	4	102	2	CID000008115
Drug	AC1L1JAO	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.25e-04	57	102	4	CID000004955
Drug	econazole	FRMD7 TRPV6 TRPV5 CNTN2	1.25e-04	57	102	4	CID000003198
Drug	benznidazole	AOX1 XDH GMPR2	1.26e-04	22	102	3	CID000031593
Drug	AC1L1KS5	NT5C1A P2RX4 TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3	1.31e-04	334	102	8	CID000005631
Drug	toxaphene	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.34e-04	58	102	4	CID005284469
Drug	ethylketocyclazocine	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.34e-04	58	102	4	CID000135018
Drug	dithiotreitol	INSR XDH PFKM ME3 NT5C1A ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.37e-04	430	102	9	CID000019001
Drug	N1-methylnicotinamide	AOX1 XDH ITGA9	1.45e-04	23	102	3	CID000000457
Drug	pirimiphos methyl	SHMT1 HARBI1 OXCT1 MACF1 YIPF3 SYNCRIP	1.52e-04	178	102	6	ctd:C014153
Drug	sanguinarine	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.53e-04	60	102	4	CID000005154
Drug	arabinosyladenine	XDH UPF1 PFKM NT5C1A P2RX4 SLC28A2 ATP2B1 ATP2B2 ATP2B3 CPSF3 ATP2B4 PKN3	1.55e-04	762	102	12	CID000000191
Drug	4-nitrohippuric acid	AOX1 GMPR2	1.97e-04	5	102	2	CID000017549
Drug	pyrimidin-4-one	AOX1 XDH	1.97e-04	5	102	2	CID000020695
Drug	citric acid	SLC11A2 ACLY PEPD PFKM ME3 OXCT1 OXSM CPSF3	2.06e-04	357	102	8	CID000000311
Drug	fura 2	SLC11A2 ATP2B1 ATP2B2 PKN3	2.08e-04	65	102	4	CID000057054
Drug	AC1L1MAZ	AOX1 XDH GMPR2	2.11e-04	26	102	3	CID000031772
Drug	caffeine	XDH UPF1 NT5C1A P2RX4 TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 VCL	2.16e-04	562	102	10	CID000002519
Drug	manganese	SLC11A2 INSR PEPD ISG20 UPF1 ITGA9 TRPV6 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.19e-04	791	102	12	CID000023930
Drug	Piperine [94-62-2]; Down 200; 14uM; MCF7; HT_HG-U133A	DEAF1 HSDL2 ACLY ISG20 SLC25A37 MACF1	2.29e-04	192	102	6	4830_DN
Drug	chlordecone	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.34e-04	67	102	4	CID000000299
Drug	dihydropyridine	TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3	2.35e-04	193	102	6	CID000104822
Drug	ara-Hx	XDH UPF1 GMPR2 PFKM NT5C1A SLC28A2	2.35e-04	193	102	6	CID000000804
Drug	p-nitrophenyl phosphate	INSR OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.42e-04	194	102	6	CID000000378
Drug	strontium	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.48e-04	68	102	4	CID000104798
Drug	NSC3260	OXCT1 TRPV6 ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.49e-04	195	102	6	CID000220461
Drug	magnesium	INSR PEPD UPF1 PFKM ITGA9 NT5C1A SPHK1 MTR TRPV6 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4 TRPV5 PKN3	2.62e-04	1325	102	16	CID000000888
Drug	L-beta-aspartyl phosphate	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.62e-04	69	102	4	CID000000832
Drug	Cytisine (-) [485-35-8]; Down 200; 21uM; MCF7; HT_HG-U133A	SETD1B WAS SLC25A37 KLHL9 ATP11B TNK2	2.63e-04	197	102	6	6217_DN
Drug	Fenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A	ADAM19 SHMT1 ATP2B2 ATP2B3 TRPV5 TBL2	2.63e-04	197	102	6	2401_UP
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A	AOX1 ACOT7 SLC25A37 KLHL9 ATP11B MACF1	2.70e-04	198	102	6	7323_DN
Drug	(cis-) Nanophine [5072-45-7]; Up 200; 26.8uM; PC3; HT_HG-U133A	XDH APOBR GFOD2 SLC28A2 TNK2 TBL2	2.78e-04	199	102	6	4543_UP
Drug	Pyrethroids	ATP2B1 ATP2B2 ATP2B3 ATP2B4	2.93e-04	71	102	4	CID000005053
Drug	mebeverine	OXSM VCL	2.95e-04	6	102	2	CID000004031
Drug	BOF-4272	AOX1 XDH	2.95e-04	6	102	2	CID000121917
Drug	hydroxyl radicals	AOX1 ACOT7 SHMT1 XDH PFKM ACY1 NT5C1A ATP11B PTPRN2 MTR OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4 PKN3	2.99e-04	1341	102	16	CID000000961
Drug	monobromobimane	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.09e-04	72	102	4	CID000114810
Drug	isooctane	MTR PACS2 OXSM	3.25e-04	30	102	3	CID000010907
Drug	cocaethylene	ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.26e-04	73	102	4	CID000002825
Drug	hydride	SLC11A2 INSR SHMT1 XDH GMPR2 ATP11B SLC28A2 OXSM ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.58e-04	835	102	12	CID000000783
Drug	beta-NADP	ACLY SHMT1 XDH GMPR2 PFKM ME3 MTR OXSM VAT1	3.59e-04	490	102	9	CID000000929
Drug	benzoquinone	PFKM PRPF40A ATP2B1 ATP2B2 ATP2B3 ATP2B4	3.61e-04	209	102	6	CID000004650
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B1 ATP2B2 ATP2B3 ATP2B4	1.71e-09	6	98	4	DOID:0050429 (implicated_via_orthology)
Disease	xanthinuria (implicated_via_orthology)	AOX1 XDH	1.09e-05	2	98	2	DOID:0060236 (implicated_via_orthology)
Disease	Malignant neoplasm of breast	FNDC3B SHMT1 XDH ACY1 ITGA9 RFX2 HELQ TXNDC15 MTR MACF1 OXSM CPSF3 ZNF541 DOP1A	1.25e-05	1074	98	14	C0006142
Disease	obsolete_red blood cell distribution width	DIP2B FNDC3B SETD1B INSR PEPD SHMT1 MFSD2B ZNF407 SLC25A37 ME3 ATP11B SPHK1 ATP2B3 ATP2B4 TBL2	3.74e-05	1347	98	15	EFO_0005192
Disease	hemoglobin A1 measurement	FNDC3B MFSD2B PFKM SLC25A37 INTS14 ATP11B MACF1 TRPV6 ATP2B4	6.00e-05	520	98	9	EFO_0007629
Disease	mean corpuscular hemoglobin concentration	FNDC3B SLC11A2 SETD1B ISG20 GMPR2 PFKM SLC25A37 ME3 ATP11B MACF1 SLC25A28 ATP2B4	3.00e-04	1105	98	12	EFO_0004528
Disease	reticulocyte count	FNDC3B ACLY INSR PEPD MFSD2B PFKM SLC25A37 ATP11B SPHK1 ATP2B1 ATP2B4	7.03e-04	1045	98	11	EFO_0007986
Disease	chronic kidney disease (implicated_via_orthology)	INSR XDH	7.05e-04	12	98	2	DOID:784 (implicated_via_orthology)
Disease	testosterone measurement	DIP2B CECR2 INSR XDH SLC25A37 TXNDC15 MACF1 NUDC ATP2B2 ATP2B4 TBL2 PKN3	1.06e-03	1275	98	12	EFO_0004908
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	DIP2B ATP2B1	1.44e-03	17	98	2	DOID:0060307 (is_implicated_in)
Disease	Antihypertensive use measurement	DIP2B INSR ATP2B1 ATP2B2 ATP2B4	1.94e-03	265	98	5	EFO_0009927
Disease	serum alanine aminotransferase measurement	DIP2B FNDC3B INSR PEPD SHMT1 XDH NUDC SLC25A28 TBL2	2.43e-03	869	98	9	EFO_0004735
Disease	Pseudoaphakia	LIM2 ATP2B1	2.87e-03	24	98	2	C0524524
Disease	Lens Opacities	LIM2 ATP2B1	2.87e-03	24	98	2	C1510497

Protein segments in the cluster

Peptide	Gene	Start	Entry
QHMDAGGVRMEVVSV	UMODL1	836	Q5DID0
HGGVTMKLMDEVAGI	ACOT7	246	O00154
VMHARSGGNLEVMGL	COPS5	66	Q92905
AGHVLGAAMFMIEIA	CPSF3	156	Q9UKF6
MFHVAGAQEMGTVAA	NT5C1A	331	Q9BXI3
AIGVAATMAHEMGHN	ADAM19	336	Q9H013
GPISMNHGVHFMAAI	DOP1A	1816	Q5JWR5
MIAHGSNVMSADGAG	ANKRD24	101	Q8TF21
GLGHFQAVMMEQIGT	CECR2	1416	Q9BXF3
LSGTHVMEGSGRMVV	ATP2B1	261	P20020
GTHVMEGSGRMLVTA	ATP2B2	261	Q01814
HVMEGSGRMVVTAVG	ATP2B3	266	Q16720
HVMEGSGRMVVTAVG	ATP2B4	261	P23634
GRPADKIQMAMVHGV	TNK2	956	Q07912
THGGIEMGQGVHTKM	AOX1	1041	Q06278
MNAVFSVGGDVMHPD	AP4E1	451	Q9UPM8
HSFQDMAVEGGIMGI	P2RX4	241	Q99571
LAHMGILSGSVDAMV	PEPD	341	P12955
VDAMVQAHLGAVFMP	PEPD	351	P12955
EVVAMDCEMVGLGPH	ISG20	6	Q96AZ6
IHMRVAAQGFVVGAM	HIGD1A	61	Q9Y241
GMAELMAGLMQGVDH	PTPRN2	331	Q92932
MAGLMQGVDHGVARG	PTPRN2	336	Q92932
ADQVATGVAIGMGMI	OXSM	141	Q9NWU1
GGLVMGMVVTSAIFH	OR10H5	151	Q8NGA6
ISGIIMGIMAFAHQP	LIM2	76	P55344
AGAGRENGMETPMHE	LENG8	21	Q96PV6
QVMGIPQSHMAEMTG	FANCM	156	Q8IYD8
DGEGMQIHLAVAHMG	FRMD7	196	Q6ZUT3
MATEHVNGNGTEEPM	SYNCRIP	1	O60506
MPGVMGVVDCIHVAI	HARBI1	141	Q96MB7
HTVAVMNVGAPAAGM	PFKM	401	P08237
QDVGHVMPGGMMCIV	DIP2B	721	Q9P265
MVAGAVAGILEHCVM	SLC25A28	76	Q96A46
MKVSLGNGEMGVSAH	KLHL9	1	Q9P2J3
IHTAAMDMLGGPGIE	HSDL2	201	Q6YN16
TVEMAGTLMGATVHG	MFSD2B	186	A6NFX1
AVGIVGAVIMPHNMY	SLC11A2	256	P49281
QHTIMAGNVVTGEMV	GMPR2	151	Q9P2T1
GQPTLVVMELMAHGD	INSR	1096	P06213
HVAHMGPGDGMQVLM	CDC42BPB	1591	Q9Y5S2
SISMAEVMQHPSEGG	PACS2	136	Q86VP3
MVPGDVAMSGHRVGA	KIF25-AS1	86	Q9Y6Z4
MMEPREAGQHVGAAN	MRGPRE	1	Q86SM8
TADMHIIINGEDMGP	NEURL2	201	Q9BR09
NEAVLSPGMMHGIVD	MACF1	2611	Q9UPN3
GAERGGLMVSEMESH	PRPF40A	6	O75400
GGAEMFHVQEMVVGQ	ITGA9	836	Q13797
QIGMISAGPSHVAAM	UPF1	976	Q92900
VAVMAAEPGHMDMGA	DEAF1	66	O75398
GEVAMMPHLVNGDAA	FNDC3B	21	Q53EP0
GMVAIVQLGPEWHGM	INTS14	321	Q96SY0
FNMPGAFVHEVMVVG	GFOD2	241	Q3B7J2
AEVHIVRNGGTSMMV	CNTN2	996	Q02246
GAGEAAMGIAHLLVM	ME3	336	Q16798
HMIGEGSRGATLEMT	HELQ	466	Q8TDG4
MEQIQPEGIVGSMEH	ERICH5	296	Q6P6B1
EDGSMSVTGIMGHAV	GEMIN6	51	Q8WXD5
MGHAVQTVETMNEGD	GEMIN6	61	Q8WXD5
GGGMVDVMCSFVPHQ	CFAP47	466	Q6ZTR5
GIAVLEQMENHGVMP	ECSIT	161	Q9BQ95
GGLVMGMVVTSAIFH	OR10H1	151	Q9Y4A9
GIPSMAGHSMVLVEV	PCDHA12	326	Q9UN75
FVPGGDLMMQIHEDV	PKN3	641	Q6P5Z2
MMAAAPIQQNGTHTG	NOVA1	1	P51513
MADMAHISGLVAAGV	SHMT1	226	P34896
AVPSHSMVGITMDVG	RFX2	126	P48378
PMGDVHIAIMDRSGQ	RIMS3	156	Q9UJD0
GVNVMIMGAGPAHAM	SLC25A37	106	Q9NYZ2
HAIKSGMDMGIVNAG	MTR	601	Q99707
MPFAGVLEHIGGIME	SLITRK2	196	Q9H156
FHQLGTAMPMSVEEG	POLR1H	61	Q9P1U0
EMSGVHQGGNLLMGV	CCT8L1P	466	A6NM43
SDVMAEMSGVHQGGN	CCT8L2	461	Q96SF2
EMSGVHQGGNLLMGV	CCT8L2	466	Q96SF2
GLFPVMQVDMSHVLG	SETD1B	751	Q9UPS6
GGHVDLTMLGAMQVS	OXCT1	391	P55809
DGMLLAMAQQHEGGV	NUDC	11	Q9Y266
GDMTLSEIHAVMTGG	SLC28A2	326	O43868
GTETHMTAIVGMALG	ACLY	406	P53396
LVGVMSHELGHVLGM	ADAMDEC1	346	O15204
MTFVPDEEVGGHQGM	ACY1	141	Q03154
QTARAEGMGAMVEAG	APOBR	861	Q0VD83
VSMIQEAHVGIGIMG	ATP11B	826	Q9Y2G3
MGCMVGADVLVGRHQ	SLC35F1	196	Q5T1Q4
GQNSVMEAIRHGVPM	UGT3A1	371	Q6NUS8
QVHGKMERVAVMPAG	STBD1	246	O95210
GMNGIHVCMVFEVLG	SRPK2	156	P78362
TQGDHMVMLSVIPGE	TXNDC15	86	Q96J42
GLVAEGHRLANVMMG	VCL	521	P18206
MDEGDAAIMHPGVVC	WDFY4	821	Q6ZS81
QSSEGLVGALMHVMQ	WAS	461	P42768
LAGVEGNTVMFQHLM	TRPV6	286	Q9H1D0
MAEEGIAAGGVMDVN	RPS12	1	P25398
DVMAANGVIHMLDGI	STAB1	626	Q9NY15
GTEMGQGLHTKMVQV	XDH	1036	P47989
VMYGGVLVQEHVTMG	VILL	461	O15195
DPTFVMGHAMATGLV	TTC38	61	Q5R3I4
SVLVHMAAGGVGMAA	VAT1	191	Q99536
IQGGGSAVIDMENMD	YIPF3	26	Q9GZM5
VVMSGDGLMHEVVNG	SPHK1	76	Q9NYA1
VVVVGGSMEGHGMDE	ZNF407	1941	Q9C0G0
GAVHMVAGEGAQIIM	ZNF407	2111	Q9C0G0
VMGGVVQASLSIHGM	SLC5A12	401	Q1EHB4
IVMASHMQEQEVGDG	CCT8	86	P50990
NTPGHRAMVEEMQGH	TBL2	401	Q9Y4P3
LAGVEGNTVMFQHLM	TRPV5	246	Q9NQA5
VPVTRHIGSMAMGQE	ZNF541	921	Q9H0D2