Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA helicase activity

UPF1 EIF4A1 EIF4A2 DDX5 DDX54

5.36e-0778415GO:0003724
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

UPF1 EIF4A1 EIF4A2 DDX5 DDX54

6.09e-0780415GO:0008186
GeneOntologyMolecularFunctionhelicase activity

CHD3 UPF1 EIF4A1 EIF4A2 DDX5 DDX54

7.98e-07158416GO:0004386
GeneOntologyMolecularFunctionATP hydrolysis activity

CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

2.87e-05441417GO:0016887
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

RGS14 CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

1.52e-04775418GO:0017111
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

UPF1 EIF4A1 EIF4A2 DDX5 DDX54 FTSJ3

1.94e-04417416GO:0140098
GeneOntologyMolecularFunctionATP-dependent activity

CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

2.27e-04614417GO:0140657
GeneOntologyMolecularFunctionpyrophosphatase activity

RGS14 CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

2.61e-04839418GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

RGS14 CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

2.64e-04840418GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

RGS14 CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

2.64e-04840418GO:0016818
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

CHD3 UPF1 EIF4A1 EIF4A2 DDX5 DDX54 FTSJ3

3.07e-04645417GO:0140640
GeneOntologyMolecularFunctionchromatin binding

SREBF1 PRDM8 CHD3 UPF1 AKAP8 AHDC1 DDX5

6.93e-04739417GO:0003682
GeneOntologyBiologicalProcesstranslation

MRPL41 LSM14A UPF1 MRPL15 TRIM3 EIF4A1 PPP1R15B EIF4A2 RPS9

2.22e-05824409GO:0006412
GeneOntologyBiologicalProcessnuclear transport

SHH RGS14 NOP9 UPF1 CHTOP DDX5

8.25e-05378406GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

SHH RGS14 NOP9 UPF1 CHTOP DDX5

8.25e-05378406GO:0006913
GeneOntologyCellularComponentribonucleoprotein complex

MRPL41 LSM14A NOP9 UPF1 MRPL15 SNRPD1 CD2BP2 DDX5 RPS9 FTSJ3

7.85e-0511944110GO:1990904
GeneOntologyCellularComponenteukaryotic translation initiation factor 4F complex

EIF4A1 EIF4A2

2.89e-0413412GO:0016281
GeneOntologyCellularComponentpreribosome, small subunit precursor

NOP9 FTSJ3

3.88e-0415412GO:0030688
GeneOntologyCellularComponentRNA cap binding complex

EIF4A1 EIF4A2

5.01e-0417412GO:0034518
GeneOntologyCellularComponentcomplex of collagen trimers

COL4A3 COL11A2

7.70e-0421412GO:0098644
GeneOntologyCellularComponentU5 snRNP

SNRPD1 CD2BP2

1.09e-0325412GO:0005682
GeneOntologyCellularComponentmethyltransferase complex

KMT2C PRDM8 SNRPD1

1.24e-03108413GO:0034708
GeneOntologyCellularComponentpreribosome

NOP9 RPS9 FTSJ3

1.45e-03114413GO:0030684
MousePhenoabsent vertebrae

SHH CHTOP

3.58e-055272MP:0000138
DomainDEAD_ATP_HELICASE

EIF4A1 EIF4A2 DDX5 DDX54

5.44e-0731404PS00039
DomainRNA-helicase_DEAD-box_CS

EIF4A1 EIF4A2 DDX5 DDX54

7.06e-0733404IPR000629
DomainRNA_helicase_DEAD_Q_motif

EIF4A1 EIF4A2 DDX5 DDX54

1.13e-0637404IPR014014
DomainQ_MOTIF

EIF4A1 EIF4A2 DDX5 DDX54

1.13e-0637404PS51195
DomainHelicase_C

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.15e-06107405PF00271
DomainHELICc

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.15e-06107405SM00490
DomainHelicase_C

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.30e-06108405IPR001650
DomainHELICASE_CTER

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.45e-06109405PS51194
DomainHELICASE_ATP_BIND_1

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.45e-06109405PS51192
DomainDEXDc

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.45e-06109405SM00487
DomainHelicase_ATP-bd

CHD3 EIF4A1 EIF4A2 DDX5 DDX54

3.61e-06110405IPR014001
DomainEIF4A1/2

EIF4A1 EIF4A2

4.47e-062402IPR031258
DomainDEAD

EIF4A1 EIF4A2 DDX5 DDX54

1.76e-0573404PF00270
DomainDEAD/DEAH_box_helicase_dom

EIF4A1 EIF4A2 DDX5 DDX54

1.76e-0573404IPR011545
DomainAT_hook

PRR12 KMT2C AHDC1

2.57e-0527403SM00384
DomainAT_hook_DNA-bd_motif

PRR12 KMT2C AHDC1

2.57e-0527403IPR017956
DomainP-loop_NTPase

MAGI3 CHD3 UPF1 EIF4A1 EIF4A2 DDX5 KIF1C DDX54

3.68e-04848408IPR027417
DomainAT_hook

PRR12 KMT2C

5.27e-0416402PF02178
DomainLSM_dom

LSM14A SNRPD1

1.01e-0322402IPR010920
DomainHMGI/Y_DNA-bd_CS

PRR12 KMT2C

2.00e-0331402IPR000637
DomainSET

KMT2C PRDM8

4.36e-0346402SM00317
Domain-

CHD3 UPF1 EIF4A1 EIF4A2 DDX5 DDX54

4.79e-037464063.40.50.300
DomainSET_dom

KMT2C PRDM8

5.13e-0350402IPR001214
DomainSET

KMT2C PRDM8

5.13e-0350402PS50280
PathwayREACTOME_METABOLISM_OF_RNA

UPF1 SNRPD1 CHTOP EIF4A1 EIF4A2 DDX5 RPS9 FTSJ3

3.92e-05612318MM15547
PathwayWP_MRNA_PROCESSING

COL4A3 NOP9 SNRPD1 CD2BP2 EIF4A2 DDX5 RPS9

4.42e-05451317MM15946
PathwayBIOCARTA_IRES_PATHWAY

EIF4A1 EIF4A2

6.98e-056312MM1550
PathwayBIOCARTA_IRES_PATHWAY

EIF4A1 EIF4A2

9.76e-057312M22028
PathwayREACTOME_METABOLISM_OF_RNA

UPF1 SNRPD1 CHTOP EIF4A1 EIF4A2 DDX5 RPS9 FTSJ3

1.28e-04724318M16843
PathwayREACTOME_TRANSLATION

MRPL41 MRPL15 EIF4A1 EIF4A2 RPS9

1.36e-04231315MM15420
PathwayBIOCARTA_AKAP95_PATHWAY

AKAP8 DDX5

2.08e-0410312MM1344
PathwayBIOCARTA_AKAP95_PATHWAY

AKAP8 DDX5

2.54e-0411312M5731
PathwayREACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

EIF4A1 EIF4A2 RPS9

3.03e-0460313M721
PathwayREACTOME_Z_DECAY_DEGRADATION_OF_MATERNAL_MRNAS_BY_ZYGOTICALLY_EXPRESSED_FACTORS

EIF4A1 EIF4A2

3.05e-0412312M48027
PathwayREACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S

EIF4A1 EIF4A2 RPS9

3.84e-0465313MM15416
PathwayREACTOME_TRANSLATION

MRPL41 MRPL15 EIF4A1 EIF4A2 RPS9

4.22e-04295315M8229
PathwayBIOCARTA_EIF_PATHWAY

EIF4A1 EIF4A2

5.51e-0416312M7721
PathwayBIOCARTA_MTOR_PATHWAY

EIF4A1 EIF4A2

8.68e-0420312MM1437
PathwayBIOCARTA_MTOR_PATHWAY

EIF4A1 EIF4A2

1.05e-0322312M16563
PathwayBIOCARTA_EIF4_PATHWAY

EIF4A1 EIF4A2

1.15e-0323312MM1470
PathwayREACTOME_DEADENYLATION_OF_MRNA

EIF4A1 EIF4A2

1.25e-0324312MM15090
PathwayBIOCARTA_EIF4_PATHWAY

EIF4A1 EIF4A2

1.25e-0324312M4791
PathwayREACTOME_DEADENYLATION_OF_MRNA

EIF4A1 EIF4A2

1.36e-0325312M13492
PathwayREACTOME_ISG15_ANTIVIRAL_MECHANISM

EIF4A1 EIF4A2

1.83e-0329312MM17065
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

COL4A3 COL11A2

2.23e-0332312MM14924
PathwayREACTOME_EUKARYOTIC_TRANSLATION_INITIATION

EIF4A1 EIF4A2 RPS9

2.27e-03120313M27686
PathwayREACTOME_M_DECAY_DEGRADATION_OF_MATERNAL_MRNAS_BY_MATERNALLY_STORED_FACTORS

EIF4A1 EIF4A2

2.37e-0333312M48026
PathwayREACTOME_EUKARYOTIC_TRANSLATION_INITIATION

EIF4A1 EIF4A2 RPS9

2.44e-03123313MM15415
PathwayWP_EFFECT_OF_PROGERIN_ON_GENES_INVOLVED_IN_PROGERIA

SREBF1 CHD3

2.97e-0337312M39756
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

PRR12 LSM14A NOP9 CHD3 UPF1 AKAP8 SNRPD1 PRRC2A AHDC1 CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

7.78e-16847411635850772
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

MRPL41 LSM14A NOP9 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP EIF4A1 EIF4A2 DDX5 KIF1C DDX54 FTSJ3

9.69e-15807411522681889
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

LSM14A NOP9 CHD3 UPF1 AKAP8 PRRC2A CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

2.31e-12759411335915203
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

MRPL41 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP CD2BP2 DDX5 RPS9 DDX54 FTSJ3

2.31e-11713411229802200
Pubmed

Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.

UPF1 AKAP8 SNRPD1 EIF4A1 DDX5 RPS9 DDX54 FTSJ3

4.23e-1024541821182205
Pubmed

Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.

MRPL41 CHD3 UPF1 SNRPD1 PRRC2A CD2BP2 DDX5 RPS9 FTSJ3

5.70e-1038441931059266
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

MRPL41 LSM14A UPF1 SNRPD1 PRRC2A CHTOP CD2BP2 DDX5 RPS9 DDX54 FTSJ3

5.84e-10731411129298432
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

CHD3 AKAP8 SNRPD1 CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

1.63e-09605411028977666
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SREBF1 PRR12 KMT2C NOP9 CHD3 AKAP8 SNRPD1 AHDC1 CHTOP CD2BP2 DDX5 DDX54 FTSJ3

1.65e-091294411330804502
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

LSM14A CHD3 UPF1 AKAP8 PRRC2A CHTOP DDX5 RPS9 DDX54 FTSJ3

3.47e-09655411035819319
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

MRPL41 LSM14A CHD3 MRPL15 SNRPD1 CHTOP EIF4A1 CD2BP2 EIF4A2 DDX5 RPS9 FTSJ3

5.41e-091153411229845934
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

LSM14A UPF1 AKAP8 MRPL15 SNRPD1 CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

1.41e-081257411236526897
Pubmed

Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.

MRPL41 LSM14A NOP9 UPF1 AKAP8 SNRPD1 CD2BP2 FTSJ3

2.07e-0840341835253629
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

MRPL41 LSM14A CHD3 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP EIF4A1 DDX5 RPS9

2.74e-081335411229229926
Pubmed

RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity.

CHD3 UPF1 SNRPD1 EIF4A1 DDX5 RPS9 DDX54 FTSJ3

3.13e-0842541821081503
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PRR12 KMT2C LSM14A CHD3 UPF1 SNRPD1 PRRC2A AHDC1 CHTOP EIF4A1 DDX5

4.10e-081103411134189442
Pubmed

Human transcription factor protein interaction networks.

PRR12 KMT2C MRPL41 LSM14A CHD3 UPF1 AKAP8 MRPL15 PRRC2A CD2BP2 DDX54 FTSJ3

5.77e-081429411235140242
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PRR12 CACNA1E MAGI3 LSM14A UPF1 SNRPD1 PRRC2A DDX5

7.35e-0847541831040226
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

MRPL41 NOP9 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A EIF4A1 DDX54

7.74e-0867841930209976
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

CHD3 UPF1 AKAP8 SNRPD1 PRRC2A CHTOP EIF4A1 DDX5 RPS9

1.20e-0771441928302793
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

PRR12 UPF1 CHTOP PPP1R15B DDX5 RPS9 FTSJ3

2.03e-0736141730344098
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NOP9 CHD3 AKAP8 SNRPD1 CHTOP EIF4A1 DDX5 RPS9 DDX54 FTSJ3

2.29e-071024411024711643
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

MRPL41 NOP9 UPF1 AKAP8 SNRPD1 AHDC1 EIF4A1 CD2BP2 DDX5 RPS9

3.80e-071082411038697112
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

MRPL41 UPF1 SNRPD1 PRRC2A EIF4A1 CD2BP2 DDX5 RPS9 KIF1C DDX54 FTSJ3

4.98e-071415411128515276
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

UPF1 PRRC2A AHDC1 CHTOP EIF4A1 DDX5 RPS9 FTSJ3

5.22e-0761541831048545
Pubmed

The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.

MRPL41 CHD3 MRPL15 DDX5 RPS9 DDX54 FTSJ3

5.36e-0741741736537216
Pubmed

SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.

LSM14A UPF1 AKAP8 PRRC2A DDX5 KIF1C

5.69e-0725841637794589
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

UPF1 AKAP8 SNRPD1 EIF4A2 DDX5 RPS9 FTSJ3

5.71e-0742141734650049
Pubmed

Circular RNA circPVT1 promotes nasopharyngeal carcinoma metastasis via the β-TrCP/c-Myc/SRSF1 positive feedback loop.

UPF1 AKAP8 EIF4A1 DDX5 RPS9 FTSJ3

5.95e-0726041636199071
Pubmed

Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.

UPF1 PRRC2A EIF4A1 CD2BP2 DDX5 RPS9 FTSJ3

7.79e-0744141731239290
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

ZNF469 NOP9 CHD3 UPF1 AKAP8 CHTOP DDX5 DDX54

8.19e-0765341833742100
Pubmed

A-kinase-anchoring protein AKAP95 is targeted to the nuclear matrix and associates with p68 RNA helicase.

AKAP8 DDX5

1.36e-06241211279182
Pubmed

Prdm8 regulates pMN progenitor specification for motor neuron and oligodendrocyte fates by modulating the Shh signaling response.

SHH PRDM8

1.36e-06241232680935
Pubmed

A cellular response linking eIF4AI activity to eIF4AII transcription.

EIF4A1 EIF4A2

1.36e-06241222589333
Pubmed

Translational dysregulation in cancer: eIF4A isoforms and sequence determinants of eIF4A dependence.

EIF4A1 EIF4A2

1.36e-06241226614665
Pubmed

Differential expression of the murine eukaryotic translation initiation factor isogenes eIF4A(I) and eIF4A(II) is dependent upon cellular growth status.

EIF4A1 EIF4A2

1.36e-0624129015395
Pubmed

Regulation of eukaryotic initiation factor 4AII by MyoD during murine myogenic cell differentiation.

EIF4A1 EIF4A2

1.36e-06241224466343
Pubmed

The mouse protein synthesis initiation factor 4A gene family includes two related functional genes which are differentially expressed.

EIF4A1 EIF4A2

1.36e-0624123046931
Pubmed

R2TP/Prefoldin-like component RUVBL1/RUVBL2 directly interacts with ZNHIT2 to regulate assembly of U5 small nuclear ribonucleoprotein.

UPF1 SNRPD1 CD2BP2 DDX5 KIF1C FTSJ3

1.37e-0630041628561026
Pubmed

A bead-based approach for large-scale identification of in vitro kinase substrates.

LSM14A AKAP8 CD2BP2 DDX54 FTSJ3

1.39e-0616341522113938
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

MRPL41 UPF1 AKAP8 PRRC2A EIF4A1 CD2BP2 DDX5 RPS9 DDX54

1.56e-0697141933306668
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

MRPL41 NOP9 AKAP8 SNRPD1 EIF4A1 CD2BP2 EIF4A2 FTSJ3

1.75e-0672341834133714
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

LSM14A CHD3 UPF1 AKAP8 SNRPD1 PRRC2A CHTOP TRIM3 CD2BP2 FTSJ3

3.22e-061371411036244648
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

LSM14A UPF1 AKAP8 PRRC2A CHTOP EIF4A1 DDX5

3.40e-0655141734728620
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

UPF1 MRPL15 SNRPD1 PRRC2A EIF4A2 DDX5 RPS9

3.69e-0655841727591049
Pubmed

Phosphorylated p68 RNA helicase activates Snail1 transcription by promoting HDAC1 dissociation from the Snail1 promoter.

CHD3 DDX5

4.06e-06341220676135
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

CHD3 UPF1 AKAP8 SNRPD1 EIF4A1 EIF4A2 DDX5

4.87e-0658241720467437
Pubmed

The intracellular interactome of tetraspanin-enriched microdomains reveals their function as sorting machineries toward exosomes.

SNRPD1 EIF4A1 EIF4A2 DDX5 RPS9

5.03e-0621241523463506
Pubmed

Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.

LSM14A UPF1 SNRPD1 EIF4A1 DDX5 RPS9

5.57e-0638341629331416
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

CHD3 MRPL15 SNRPD1 CHTOP EIF4A1 EIF4A2 DDX5 RPS9

5.61e-0684741835235311
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

UPF1 AKAP8 SNRPD1 PRRC2A EIF4A1 EIF4A2 DDX5 RPS9 FTSJ3

6.14e-06114941935446349
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

LSM14A AKAP8 SNRPD1 CHTOP EIF4A1 CD2BP2 EIF4A2 DDX5 KIF1C

6.40e-06115541920360068
Pubmed

BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates.

MRPL41 UPF1 MRPL15 PRRC2A PPP1R15B

6.86e-0622641525900982
Pubmed

The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A.

EIF4A1 EIF4A2

8.12e-0644128449919
Pubmed

Novel Upf2p orthologues suggest a functional link between translation initiation and nonsense surveillance complexes.

UPF1 EIF4A1

8.12e-06441211073994
Pubmed

mRNA helicases: the tacticians of translational control.

EIF4A1 EIF4A2

8.12e-06441221427765
Pubmed

Eukaryotic initiation factors 4A (eIF4A) and 4G (eIF4G) mutually interact in a 1:1 ratio in vivo.

EIF4A1 EIF4A2

8.12e-06441211408474
Pubmed

The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells.

UPF1 SNRPD1 CHTOP EIF4A1 DDX5

9.00e-0623941526641092
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

CHD3 UPF1 SNRPD1 CHTOP DDX5 RPS9 DDX54

9.12e-0664141736057605
Pubmed

Nucleolar proteome dynamics.

NOP9 CHD3 DDX5 RPS9 DDX54 FTSJ3

9.29e-0641941615635413
Pubmed

Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.

UPF1 EIF4A1 DDX5 RPS9 KIF1C

9.37e-0624141523125841
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

AKAP8 SNRPD1 PRRC2A CD2BP2 DDX5

9.95e-0624441529884807
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

SNRPD1 CHTOP EIF4A1 DDX5 RPS9 FTSJ3

1.08e-0543041638172120
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

LSM14A CHD3 UPF1 PRRC2A CHTOP DDX5 RPS9 FTSJ3

1.14e-0593441833916271
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

UPF1 PRRC2A AHDC1 CHTOP EIF4A1 DDX5 RPS9 DDX54 FTSJ3

1.18e-05124741927684187
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

UPF1 MRPL15 SNRPD1 EIF4A1 DDX5 RPS9 DDX54 FTSJ3

1.28e-0594941836574265
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

MRPL15 SNRPD1 RPS9 DDX54 FTSJ3

1.33e-0525941530404004
Pubmed

Mouse erythroid cells express multiple putative RNA helicase genes exhibiting high sequence conservation from yeast to mammals.

EIF4A1 DDX5

1.35e-0554128144024
Pubmed

Regulation of translation initiation in eukaryotes: mechanisms and biological targets.

EIF4A1 EIF4A2

1.35e-05541219239892
Pubmed

Global Hypertranscription in the Mouse Embryonic Germline.

EIF4A2 RPS9

1.35e-05541228591571
Pubmed

A catalogue of putative HIV-1 protease host cell substrates.

UPF1 AKAP8 EIF4A2 DDX5

1.41e-0512441422944692
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

PRR12 KMT2C AKAP8 SNRPD1 AHDC1 DDX5

1.52e-0545741632344865
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

CHD3 SNRPD1 DDX5 RPS9 FTSJ3

1.65e-0527141532433965
Pubmed

Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.

MRPL41 UPF1 PRRC2A TRIM3 DDX5 RPS9

1.65e-0546441632457219
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

PRR12 AKAP8 CD2BP2 EIF4A2 DDX5

1.68e-0527241531010829
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

UPF1 AKAP8 PRRC2A EIF4A1 DDX5

1.74e-0527441534244482
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

KMT2C UPF1 SNRPD1 PRRC2A CHTOP DDX5 DDX54

1.78e-0571141733022573
Pubmed

LINKIN, a new transmembrane protein necessary for cell adhesion.

LSM14A AKAP8 SNRPD1 EIF4A2 DDX5 RPS9

2.00e-0548041625437307
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

MRPL41 UPF1 SNRPD1 PRRC2A EIF4A1 DDX5 RPS9

2.02e-0572541727025967
Pubmed

The functional genes for protein synthesis initiation factor 4AI and 4AII map to mouse chromosomes 11 and 16.

EIF4A1 EIF4A2

2.03e-0564128439732
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

MRPL41 LSM14A CHD3 MRPL15 AHDC1 CHTOP EIF4A1

2.14e-0573241734732716
Pubmed

Mitotic phosphorylation of eukaryotic initiation factor 4G1 (eIF4G1) at Ser1232 by Cdk1:cyclin B inhibits eIF4A helicase complex binding with RNA.

EIF4A1 EIF4A2 RPS9

2.70e-054941324248602
Pubmed

Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation.

SHH COL11A2

2.84e-0574129885252
Pubmed

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.

LSM14A UPF1 PRRC2A EIF4A1 FTSJ3

3.39e-0531541526777405
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

NOP9 UPF1 SNRPD1 CHTOP EIF4A1 DDX5 RPS9 DDX54 FTSJ3

3.39e-05142541930948266
Pubmed

Transcript-selective translational silencing by gamma interferon is directed by a novel structural element in the ceruloplasmin mRNA 3' untranslated region.

EIF4A1 EIF4A2 RPS9

3.42e-055341312588972
Pubmed

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality.

COL4A3 SHH TGFBR3L

3.42e-055341333153107
Pubmed

Analysis of proteins copurifying with the CD4/lck complex using one-dimensional polyacrylamide gel electrophoresis and mass spectrometry: comparison with affinity-tag based protein detection and evaluation of different solubilization methods.

EIF4A2 DDX5 RPS9

3.42e-055341315047060
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

NOP9 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP EIF4A1 DDX54

3.68e-05144041930833792
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1E MAGI3 RGS14 LSM14A PRDM8 CHD3 EIF4A1 EIF4A2 DDX5

3.72e-05144241935575683
Pubmed

A DDX6-CNOT1 complex and W-binding pockets in CNOT9 reveal direct links between miRNA target recognition and silencing.

EIF4A1 EIF4A2

3.78e-05841224768540
Pubmed

Discoidin domain receptor 1 functions in axon extension of cerebellar granule neurons.

COL4A3 SHH

3.78e-05841210970885
Pubmed

The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.

UPF1 AKAP8 RPS9

3.82e-055541331640799
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

COL4A3 UPF1 SNRPD1 CHTOP EIF4A1 DDX5 RPS9

3.99e-0580741730575818
Pubmed

A protein-RNA interaction atlas of the ribosome biogenesis factor AATF.

UPF1 PRRC2A CHTOP RPS9

4.02e-0516241431363146
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

SNRPD1 EIF4A1 DDX5 RPS9 FTSJ3

4.22e-0533041532529326
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

CHD3 UPF1 EIF4A1 EIF4A2 DDX5

4.35e-0533241532786267
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

KMT2C MRPL15 PRRC2A EIF4A1 DDX54

4.41e-0533341536779763
Pubmed

Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases.

LSM14A CHTOP

4.86e-05941219858291
Pubmed

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis.

AKAP8 SNRPD1 RPS9 FTSJ3

5.07e-0517241426336360
InteractionDOT1L interactions

LSM14A NOP9 CHD3 UPF1 AKAP8 SNRPD1 PRRC2A AHDC1 CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

1.52e-118074015int:DOT1L
InteractionHECTD1 interactions

SREBF1 LSM14A NOP9 CHD3 UPF1 AKAP8 PRRC2A CHTOP EIF4A1 CD2BP2 EIF4A2 DDX5 RPS9 DDX54 FTSJ3

2.45e-109844015int:HECTD1
InteractionMEN1 interactions

PRR12 KMT2C NOP9 CHD3 UPF1 AKAP8 SNRPD1 PRRC2A AHDC1 CHTOP EIF4A1 CD2BP2 DDX5 DDX54 FTSJ3

4.56e-1010294015int:MEN1
InteractionSNRNP70 interactions

MRPL41 CHD3 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP CD2BP2 DDX5 RPS9 DDX54 FTSJ3

2.91e-089844013int:SNRNP70
InteractionCEBPA interactions

PRR12 KMT2C LSM14A CHD3 UPF1 SNRPD1 PRRC2A AHDC1 CHTOP EIF4A1 DDX5 RPS9 DDX54 FTSJ3

5.57e-0812454014int:CEBPA
InteractionFMR1 interactions

MAGI3 LSM14A CHD3 UPF1 AKAP8 PRRC2A CHTOP TRIM3 DDX5 RPS9

6.74e-085364010int:FMR1
InteractionZC3H18 interactions

MRPL41 LSM14A CHD3 UPF1 SNRPD1 PRRC2A CHTOP CD2BP2 DDX5 RPS9 DDX54 FTSJ3

7.75e-088774012int:ZC3H18
InteractionKLF15 interactions

PRR12 KMT2C MRPL41 LSM14A AKAP8 MRPL15 PRRC2A FTSJ3

8.61e-08290408int:KLF15
InteractionNFX1 interactions

MRPL41 CHD3 UPF1 SNRPD1 PRRC2A CD2BP2 DDX5 RPS9 FTSJ3

2.53e-07466409int:NFX1
InteractionRBM8A interactions

NOP9 UPF1 PRRC2A CHTOP EIF4A1 EIF4A2 DDX5 RPS9 FTSJ3

2.87e-07473409int:RBM8A
InteractionRPL19 interactions

MRPL41 CHD3 MRPL15 PRRC2A EIF4A1 DDX5 TCEAL5 RPS9 DDX54 FTSJ3

3.39e-076384010int:RPL19
InteractionRC3H1 interactions

MRPL41 LSM14A NOP9 UPF1 MRPL15 SNRPD1 PRRC2A EIF4A1 CD2BP2 DDX54

5.83e-076774010int:RC3H1
InteractionRNF113A interactions

LSM14A CHD3 UPF1 AKAP8 PRRC2A CHTOP DDX5 RPS9 DDX54 FTSJ3

7.12e-076924010int:RNF113A
InteractionPABPC1 interactions

KMT2C LSM14A CHD3 UPF1 SNRPD1 PRRC2A EIF4A1 EIF4A2 DDX5 RPS9

7.80e-076994010int:PABPC1
InteractionILF3 interactions

RGS14 MRPL41 LSM14A CHD3 UPF1 MRPL15 SNRPD1 DDX5 RPS9 DDX54 FTSJ3

8.92e-078964011int:ILF3
InteractionHEXIM1 interactions

MRPL41 LSM14A CHD3 SNRPD1 CHTOP EIF4A1 CD2BP2 EIF4A2 DDX5 RPS9 FTSJ3

1.07e-069134011int:HEXIM1
InteractionHNRNPA1 interactions

LSM14A CHD3 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP EIF4A2 DDX5 RPS9

1.50e-069454011int:HNRNPA1
InteractionCHD3 interactions

CHD3 AKAP8 SNRPD1 CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

1.61e-067574010int:CHD3
InteractionSRP9 interactions

UPF1 SNRPD1 PRRC2A EIF4A1 EIF4A2 RPS9 DDX54 FTSJ3

1.61e-06427408int:SRP9
InteractionEIF4ENIF1 interactions

LSM14A NOP9 UPF1 PRRC2A EIF4A1 EIF4A2 FTSJ3

1.85e-06300407int:EIF4ENIF1
InteractionBTRC interactions

MRPL41 UPF1 AKAP8 MRPL15 PRRC2A EIF4A1 PPP1R15B DDX5 RPS9 FTSJ3

1.98e-067754010int:BTRC
InteractionSOX2 interactions

PRR12 KMT2C MRPL41 LSM14A CHD3 UPF1 AKAP8 MRPL15 AHDC1 CHTOP EIF4A1 DDX5 FTSJ3

2.02e-0614224013int:SOX2
InteractionFBL interactions

LSM14A CHD3 UPF1 PRRC2A AHDC1 DDX5 RPS9 DDX54 FTSJ3

3.47e-06639409int:FBL
InteractionRBM42 interactions

SNRPD1 PRRC2A EIF4A1 CD2BP2 EIF4A2 DDX5 RPS9

3.54e-06331407int:RBM42
InteractionU2AF2 interactions

CHD3 UPF1 MRPL15 SNRPD1 CHTOP TRIM3 EIF4A1 DDX5 FTSJ3

4.04e-06651409int:U2AF2
InteractionOASL interactions

NOP9 UPF1 AKAP8 CHTOP DDX54 FTSJ3

4.81e-06223406int:OASL
InteractionRC3H2 interactions

MRPL41 LSM14A NOP9 UPF1 AKAP8 SNRPD1 PRRC2A EIF4A1 DDX54

4.92e-06667409int:RC3H2
InteractionEIF4A3 interactions

CHD3 UPF1 SNRPD1 CHTOP EIF4A1 EIF4A2 DDX5 RPS9

5.12e-06499408int:EIF4A3
InteractionEIF4A1 interactions

CHD3 UPF1 PRRC2A EIF4A1 EIF4A2 DDX5 KIF1C

5.61e-06355407int:EIF4A1
InteractionMECOM interactions

SREBF1 MAGI3 CHD3 UPF1 AKAP8 SNRPD1 FTSJ3

5.93e-06358407int:MECOM
InteractionPSPC1 interactions

UPF1 PRRC2A EIF4A1 CD2BP2 EIF4A2 DDX5 RPS9 FTSJ3

6.45e-06515408int:PSPC1
InteractionCAND1 interactions

MRPL41 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A EIF4A1 DDX5 RPS9 FTSJ3

7.07e-068944010int:CAND1
InteractionMYCN interactions

MRPL41 LSM14A UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP DDX5 RPS9 DDX54 FTSJ3

8.88e-0613734012int:MYCN
InteractionE2F4 interactions

MRPL41 LSM14A NOP9 UPF1 AKAP8 SNRPD1 CD2BP2 FTSJ3

9.11e-06540408int:E2F4
InteractionSYNCRIP interactions

RGS14 LSM14A CHD3 UPF1 SNRPD1 PRRC2A DDX5 RPS9 DDX54

9.23e-06721409int:SYNCRIP
InteractionRPS16 interactions

NOP9 CHD3 UPF1 PRRC2A EIF4A1 EIF4A2 DDX5 RPS9 FTSJ3

9.54e-06724409int:RPS16
InteractionPRRC2A interactions

LSM14A UPF1 MRPL15 PRRC2A EIF4A1 EIF4A2 DDX54

1.02e-05389407int:PRRC2A
InteractionPPP1CC interactions

PRR12 CHD3 UPF1 CHTOP CD2BP2 PPP1R15B DDX5 RPS9 FTSJ3

1.11e-05738409int:PPP1CC
InteractionRECQL4 interactions

MRPL41 LSM14A CHD3 UPF1 AKAP8 MRPL15 SNRPD1 PRRC2A CHTOP EIF4A1 DDX5 RPS9

1.18e-0514124012int:RECQL4
InteractionHDAC4 interactions

PRR12 CACNA1E MAGI3 LSM14A UPF1 SNRPD1 PRRC2A DDX5 KIF1C

1.19e-05744409int:HDAC4
InteractionRIOK1 interactions

CHD3 UPF1 CHTOP EIF4A1 DDX5 RPS9 DDX54 FTSJ3

1.22e-05562408int:RIOK1
InteractionCSNK2A1 interactions

LSM14A CHD3 UPF1 AKAP8 HAGHL CD2BP2 RPS9 KIF1C DDX54 FTSJ3

1.27e-059564010int:CSNK2A1
InteractionYBX1 interactions

MRPL41 LSM14A CHD3 UPF1 MRPL15 SNRPD1 RPS9 DDX54 FTSJ3

1.29e-05752409int:YBX1
InteractionUNK interactions

LSM14A UPF1 PRRC2A EIF4A1 PPP1R15B EIF4A2 DDX5

1.39e-05408407int:UNK
InteractionNPM1 interactions

RGS14 MRPL41 CHD3 SNRPD1 PRRC2A EIF4A1 EIF4A2 DDX5 RPS9 DDX54 FTSJ3

1.50e-0512014011int:NPM1
InteractionEFTUD2 interactions

MRPL41 CHD3 UPF1 SNRPD1 PRRC2A EIF4A1 CD2BP2 DDX5 RPS9 KIF1C DDX54 FTSJ3

1.53e-0514494012int:EFTUD2
InteractionILF2 interactions

CHD3 UPF1 SNRPD1 EIF4A1 DDX5 RPS9 KIF1C FTSJ3

1.73e-05590408int:ILF2
InteractionTOP3B interactions

SREBF1 PRR12 KMT2C LSM14A UPF1 PRRC2A AHDC1 PRRT4 EIF4A1 CD2BP2 PPP1R15B EIF4A2

1.77e-0514704012int:TOP3B
InteractionCBX6 interactions

UPF1 MRPL15 AHDC1 CHTOP DDX54 FTSJ3

1.87e-05283406int:CBX6
InteractionAURKAIP1 interactions

MRPL41 CHD3 MRPL15 CHTOP DDX54 FTSJ3

1.91e-05284406int:AURKAIP1
InteractionEIF4A2 interactions

UPF1 PRRC2A EIF4A1 CD2BP2 EIF4A2

2.15e-05171405int:EIF4A2
InteractionC1QBP interactions

RGS14 MRPL41 LSM14A MRPL15 SNRPD1 PRRC2A CHTOP RPS9 DDX54

2.24e-05806409int:C1QBP
InteractionPABPC4 interactions

CHD3 PRRC2A TRIM3 EIF4A1 EIF4A2 DDX5 RPS9

2.32e-05442407int:PABPC4
InteractionRBM39 interactions

CHD3 UPF1 AKAP8 SNRPD1 PRRC2A CHTOP EIF4A1 CD2BP2 DDX5 RPS9

2.68e-0510424010int:RBM39
InteractionCD81 interactions

RGS14 SNRPD1 EIF4A1 EIF4A2 DDX5 RPS9

2.74e-05303406int:CD81
InteractionTRIM31 interactions

UPF1 AKAP8 SNRPD1 EIF4A2 DDX5 RPS9 FTSJ3

2.75e-05454407int:TRIM31
InteractionMECP2 interactions

MRPL41 NOP9 UPF1 AKAP8 SNRPD1 AHDC1 EIF4A1 CD2BP2 DDX5 RPS9 DDX54

2.85e-0512874011int:MECP2
InteractionG3BP1 interactions

LSM14A CHD3 UPF1 SNRPD1 PRRC2A EIF4A1 DDX5 RPS9 FTSJ3

2.96e-05835409int:G3BP1
InteractionWWP2 interactions

UPF1 GGN PRRC2A AHDC1 CHTOP EIF4A1 DDX5 RPS9 FTSJ3

3.10e-05840409int:WWP2
InteractionATXN2 interactions

LSM14A UPF1 PRRC2A EIF4A1 EIF4A2 DDX5

3.23e-05312406int:ATXN2
InteractionSUZ12 interactions

SREBF1 CHD3 UPF1 SNRPD1 AHDC1 CHTOP EIF4A2 DDX5

3.24e-05644408int:SUZ12
InteractionRPS8 interactions

MRPL41 NOP9 CHD3 MRPL15 PRRC2A RPS9 DDX54 FTSJ3

3.42e-05649408int:RPS8
InteractionDDX3X interactions

LSM14A CHD3 UPF1 PRRC2A EIF4A1 EIF4A2 DDX5 RPS9

3.50e-05651408int:DDX3X
InteractionHDLBP interactions

CHD3 UPF1 AKAP8 SNRPD1 PRRC2A CHTOP TRIM3 CD2BP2 FTSJ3

3.57e-05855409int:HDLBP
InteractionCDC5L interactions

CHD3 UPF1 AKAP8 SNRPD1 EIF4A1 CD2BP2 EIF4A2 DDX5 FTSJ3

3.57e-05855409int:CDC5L
InteractionKLF5 interactions

SREBF1 PRR12 KMT2C LSM14A PRRC2A

4.03e-05195405int:KLF5
InteractionSMG1 interactions

LSM14A UPF1 PRRC2A EIF4A2

4.03e-0597404int:SMG1
InteractionRPS6 interactions

RGS14 LSM14A NOP9 CHD3 UPF1 EIF4A1 RPS9 DDX54 FTSJ3

4.23e-05874409int:RPS6
InteractionPRP4K interactions

SNRPD1 PRRC2A CHTOP CD2BP2 DDX5 KIF1C

4.35e-05329406int:PRP4K
InteractionADARB1 interactions

CHD3 UPF1 SNRPD1 DDX5 RPS9 DDX54 FTSJ3

4.42e-05489407int:ADARB1
InteractionSRP72 interactions

CHD3 PRRC2A EIF4A1 RPS9 DDX54 FTSJ3

4.65e-05333406int:SRP72
InteractionEIF3B interactions

CHD3 UPF1 PRRC2A EIF4A1 EIF4A2 RPS9

4.97e-05337406int:EIF3B
InteractionRBM47 interactions

LSM14A NOP9 UPF1 MRPL15 PRRC2A

4.99e-05204405int:RBM47
InteractionMRPS30 interactions

MRPL41 LSM14A MRPL15 PRRC2A RPS9

5.47e-05208405int:MRPS30
InteractionEWSR1 interactions

SREBF1 PRR12 CHD3 UPF1 AKAP8 SNRPD1 PRRC2A CD2BP2 DDX5

5.60e-05906409int:EWSR1
InteractionIGF2BP3 interactions

LSM14A CHD3 UPF1 MRPL15 EIF4A1 DDX5 RPS9

5.62e-05508407int:IGF2BP3
InteractionKAT6A interactions

MRPL41 CHD3 MRPL15 DDX5 RPS9 DDX54 FTSJ3

5.76e-05510407int:KAT6A
InteractionTDRD3 interactions

LSM14A UPF1 PRRC2A EIF4A1 EIF4A2

5.99e-05212405int:TDRD3
InteractionSNRPB interactions

CHD3 UPF1 AKAP8 SNRPD1 CHTOP CD2BP2 DDX5

6.28e-05517407int:SNRPB
InteractionDDX21 interactions

CHD3 UPF1 AKAP8 CHTOP DDX5 RPS9 DDX54 FTSJ3

6.98e-05718408int:DDX21
InteractionCHD4 interactions

CHD3 AKAP8 CHTOP EIF4A1 CD2BP2 DDX5 RPS9 DDX54 FTSJ3

7.32e-05938409int:CHD4
InteractionMRPL2 interactions

MRPL41 MRPL15 RPS9 DDX54 FTSJ3

7.77e-05224405int:MRPL2
InteractionSMURF1 interactions

SREBF1 AKAP8 SNRPD1 DDX5 RPS9 DDX54 FTSJ3

8.64e-05544407int:SMURF1
InteractionAATF interactions

CHD3 UPF1 PRRC2A CHTOP RPS9 FTSJ3

9.10e-05376406int:AATF
InteractionCD2BP2 interactions

CHD3 SNRPD1 CD2BP2 EIF4A2 DDX5

9.17e-05232405int:CD2BP2
InteractionZNF346 interactions

UPF1 MRPL15 RPS9 KIF1C DDX54 FTSJ3

9.23e-05377406int:ZNF346
InteractionPRC1 interactions

UPF1 AKAP8 SNRPD1 EIF4A1 EIF4A2 DDX5 RPS9 DDX54 FTSJ3

9.70e-05973409int:PRC1
InteractionFUS interactions

CHD3 UPF1 AKAP8 SNRPD1 PRRC2A EIF4A1 DDX5 RPS9

1.01e-04757408int:FUS
InteractionDRG1 interactions

PRRC2A EIF4A1 EIF4A2 RPS9 DDX54 FTSJ3

1.08e-04388406int:DRG1
InteractionDDX5 interactions

CHD3 UPF1 AKAP8 SNRPD1 EIF4A1 CD2BP2 DDX5

1.13e-04568407int:DDX5
InteractionSRSF1 interactions

CHD3 UPF1 SNRPD1 CD2BP2 DDX5 DDX54 FTSJ3

1.16e-04570407int:SRSF1
InteractionRPL17 interactions

CHD3 UPF1 MRPL15 EIF4A1 RPS9 DDX54 FTSJ3

1.17e-04571407int:RPL17
InteractionYTHDF3 interactions

LSM14A UPF1 PRRC2A EIF4A1 KIF1C

1.21e-04246405int:YTHDF3
InteractionDDRGK1 interactions

MRPL41 NOP9 UPF1 SNRPD1 CHTOP EIF4A2 DDX5 RPS9 DDX54 FTSJ3

1.23e-0412494010int:DDRGK1
InteractionPTPRB interactions

MAGI3 RGS14 FTSJ3

1.41e-0451403int:PTPRB
InteractionUFL1 interactions

MRPL41 LSM14A UPF1 SNRPD1 EIF4A1 DDX5 RPS9 DDX54 FTSJ3

1.51e-041031409int:UFL1
InteractionHNRNPU interactions

LSM14A CHD3 UPF1 MRPL15 SNRPD1 DDX5 RPS9 DDX54 FTSJ3

1.55e-041035409int:HNRNPU
InteractionALYREF interactions

CHD3 UPF1 MRPL15 CHTOP DDX5 RPS9

1.58e-04416406int:ALYREF
InteractionNUP35 interactions

PRR12 KMT2C AKAP8 SNRPD1 AHDC1 DDX5

1.75e-04424406int:NUP35
InteractionTLX2 interactions

PRR12 KMT2C LSM14A DDX54

1.77e-04142404int:TLX2
CytobandEnsembl 112 genes in cytogenetic band chr17p13

CHD3 EIF4A1 KIF1C

3.66e-03346413chr17p13
CytobandEnsembl 112 genes in cytogenetic band chr19q13

PRR12 LSM14A GGN RPS9 PNMA8B

4.04e-031192415chr19q13
GeneFamilyDEAD-box helicases

EIF4A1 EIF4A2 DDX5 DDX54

4.95e-0742284499
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2C PRDM8

1.26e-0334282487
GeneFamilyCollagens

COL4A3 COL11A2

2.30e-0346282490
GeneFamilyMitochondrial ribosomal proteins

MRPL41 MRPL15

6.62e-0379282646
GeneFamilyPHD finger proteins

KMT2C CHD3

8.52e-039028288
CoexpressionWEST_ADRENOCORTICAL_TUMOR_DN

SREBF1 COL4A3 LSM14A CHD3 EIF4A1 CD2BP2 DDX5 RPS9 FTSJ3

1.34e-07546419M3837
CoexpressionGSE21927_SPLEEN_VS_TUMOR_MONOCYTE_C57BL6_DN

KMT2C LSM14A AKAP8 HAGHL PPP1R15B

1.09e-05188415M7583
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3 TRIM3

2.33e-05182414573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3 TRIM3

2.33e-051824146cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCelldroplet|World / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4A1 EIF4A2 DDX5 RPS9

2.71e-051894146e779e4f9fed7b95c4cc975b1054331d507449b2
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3 TRIM3

2.88e-05192414790282d4232311df3dac4ad97c80fc53443beccc
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3 TRIM3

2.88e-05192414b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

COL4A3 SHH MAGI3 TRIM3

3.12e-05196414484bbc6b1f58bc260964babb949d14f5df101393
ToppCellPCW_05-06|World / Celltypes from embryonic and fetal-stage human lung

SNRPD1 EIF4A1 TCEAL5 RPS9

3.18e-051974141527261e2017113d8546d382a38acbb84699d03e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E PRDM8 CHD3 TCEAL5

3.37e-052004140cb0755a101ec655359d051d6a8807408d727c55
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)|Striatum / BrainAtlas - Mouse McCarroll V32

ZNF469 PRDM8 PRRT4

2.22e-041284137e3f5cea91af005f08d8e9340fb8630bf1c887c3
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6|Striatum / BrainAtlas - Mouse McCarroll V32

ZNF469 PRDM8 PRRT4

2.22e-04128413a876303c852db2af9418d1a1711d7c950805018a
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Excitatory_Neuron.Slc17a6.Oprk1_(Claustrum_cortex)-|Striatum / BrainAtlas - Mouse McCarroll V32

ZNF469 PRDM8 PRRT4

2.22e-04128413388062f840fd04cb8087f27a9a78e7a192920e3e
ToppCellP07-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 MAGI3 SDK1

3.74e-041534135501095bcf73080872ae01128f21399f9cfc5dd1
ToppCell367C-Lymphocytic-ILC|367C / Donor, Lineage, Cell class and subclass (all cells)

COL11A2 EIF4A2 TGFBR3L

4.26e-04160413f70ec054b6d51c1565e4a257cbe3c9537c0eb09f
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte-Chondrocyte_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL11A2 SDK1 AHDC1

4.74e-0416641337794a84601a2a949d579663d4a4bb8bc8fb5923
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SDK1 TCEAL5 CCDC74A

4.74e-04166413b1bebcbe17386cb102b11d551e62d46156ce0c68
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Chondrocyte|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL11A2 SDK1 AHDC1

4.74e-0416641381c546c6d847e49e662b81e71992ca0f7a99e890
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGN DDX5 PNMA8B

4.74e-0416641366026988509e39e41274fa0de738383219e8ff30
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_11|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SDK1 TCEAL5 CCDC74A

4.83e-04167413e44743b20a7435c579d8e999ddc4ca119d6753f2
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ZNF469 TCEAL5 PNMA8B

5.00e-04169413031465190cd3623a25ef2b868daab8d932c8ff08
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

5.35e-0417341345808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

5.35e-041734137fa9dbcb258c3ab974490063951620e2def03db1
ToppCellSevere-B_naive-8|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

CHD3 GRID2IP DDX5

5.44e-04174413f3f8c924420f46321bd47e2b97f18c7241541599
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 SHH TRIM3

5.62e-04176413f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 SHH MAGI3

5.72e-041774139af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRDM8 TCEAL5 PNMA8B

6.00e-04180413d76349ecef7c5878bf215e946f032264161eb61b
ToppCelldroplet-Spleen-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4A2 DDX5 RPS9

6.10e-0418141314a04d8d69d3054b6ed3370d361dec5303ca4831
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 SHH MAGI3

6.10e-04181413b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

COL4A3 SHH MAGI3

6.30e-041834136821dca076318115d360ff426eb1218cfe104063
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 SHH MAGI3

6.40e-0418441342ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCelldroplet|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4A2 DDX5 RPS9

6.50e-041854134c8a25f36cbf43fc78d38dfeb3f1cab160bb029d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 SHH MAGI3

6.50e-04185413c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 EIF4A2 RPS9

6.60e-0418641326f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCelldroplet|World / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4A2 DDX5 RPS9

6.60e-04186413fd69a94144710d63fe047cdc50813f42ac7ab68d
ToppCellsaliva-Severe-critical_progression_d28-40|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP1R15B DDX5 RPS9

6.60e-041864130095560ca776b01aa473ad4d6015ed78fc93ff51
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRDM8 NOP9 KIF1C

6.60e-0418641374eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 SHH MAGI3

6.60e-041864133aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCelldroplet-Bladder-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHH CHD3 DDX5

6.71e-04187413663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 EIF4A2 RPS9

6.71e-0418741391c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL4A3 SHH MAGI3

6.71e-04187413ff26a533d310126521efe1d05cf8b9d32e524550
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 EIF4A2 RPS9

6.71e-04187413382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

PRDM8 NOP9 KIF1C

6.71e-041874131eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SHH SDK1

6.92e-04189413aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-bronchial_smooth_muscle_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 TCEAL5 CCDC74A

6.92e-041894134dc32b463546bbe7250dddd281b92ad17ec22da1
ToppCelldroplet-Lung-LUNG-1m-Mesenchymal-Airway_Smooth_Muscle|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 TCEAL5 CCDC74A

6.92e-041894130d06bf0d7191d13a1c4f30a7881e7ea1093bfd6f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 SHH SDK1

6.92e-041894138977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL4A3 EIF4A2 DDX5

7.02e-041904131d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

7.13e-04191413ce76b156b153a2c7c9f2fb8e563b69c81073fbe5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

7.13e-04191413c006f5a6e3a32b79ac99a78304bdd5116fc0d5e0
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 SHH TRIM3

7.13e-041914130f360766490bef3495c42f6421b22a988cfc68fb
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL4A3 SHH TRIM3

7.24e-04192413be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-ELP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MRPL15 SNRPD1 RPS9

7.24e-041924133107ac48e1d9faaea96f07332ffe611e4ebef1a7
ToppCelldroplet-Pancreas-Endocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4A2 DDX5 PNMA8B

7.24e-041924134510aa262da8dcf7c944b3907a51aba5a9397a4e
ToppCellEpithelial|World / shred on cell class and cell subclass (v4)

COL4A3 SHH MAGI3

7.24e-0419241313a3553d9a7c78535679d23d454c63fd08f7d218
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4A2 DDX5 PNMA8B

7.24e-041924130dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCellPND03-Epithelial-Epithelial_Alveolar|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

7.35e-041934135dfa69a680a0859900141c40a446d217aaa747d3
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

7.35e-04193413ebea35704ac5d21e947ae094313cf2a5205e7014
ToppCell368C-Myeloid-Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PRDM8 PPP1R15B RPS9

7.46e-04194413f9b9cbd1a418a7cbd151c2425fda6b864db9aa82
ToppCell(10)_Ciliated-(0)_Reference|(10)_Ciliated / shred by cell type by condition

MRPL41 HAGHL RPS9

7.46e-04194413f9d5bf6baddbd88947e6a740805962109649ed3b
ToppCellMild/Remission-B_memory-0|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

COL4A3 HAGHL EIF4A1

7.46e-041944134866093b50cdf895f06b60684cc3aaa9769aa4dc
ToppCellASK428|World / Donor, Lineage and Cell class of Lung cells from Dropseq

COL4A3 MAGI3 RPS9

7.57e-0419541341cbd7ea0bfab2db338b4ba0fc67cb3ae0d63d6d
ToppCell368C-Myeloid-Monocyte-CD14+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PRDM8 PPP1R15B RPS9

7.57e-041954138da933942e9033e18e25ab47831c269747b1c0b2
ToppCellCV-Severe-2|CV / Virus stimulation, Condition and Cluster

MRPL15 SNRPD1 EIF4A1

7.57e-041954131cde7f6e6c9c610bacc79014519447112c27dd9d
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

7.68e-041964139790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

COL4A3 SHH MAGI3

7.68e-04196413b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL4A3 MAGI3 SDK1

7.68e-04196413c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellEpithelial-Epithelial-A_(AT1)|Epithelial / shred on cell class and cell subclass (v4)

COL4A3 SHH TRIM3

7.68e-0419641341b21a18125cc95bc8adde3369e4abd029cf137d
ToppCellBasal-basal-9|World / Class top

EIF4A1 DDX5 RPS9

7.80e-0419741366db9eeb66b378471e4bccc2e6de51053d7cfa5c
ToppCellsevere-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KMT2C CHD3 DDX5

7.80e-0419741357ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCellBasal-basal-5|World / Class top

EIF4A1 DDX5 RPS9

7.80e-04197413267db5fc5d59eeadbc7746af08ed6e3cb3da8f3a
ToppCell(08)_Brush+PNEC-(0)_Reference|(08)_Brush+PNEC / shred by cell type by condition

MRPL41 PRRC2A RPS9

7.80e-04197413d500bfed2a76f7300f2f17b60962c18a40efd084
ToppCellCOVID_vent-Lymphocytic-T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

CHD3 EIF4A2 DDX5

7.80e-04197413ad702e440a74d54cfdcb8bb1c66bd8e0e71ab04e
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

COL4A3 SHH MAGI3

7.91e-0419841375bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-IPC_like-IPCs|1_mon / Sample Type, Dataset, Time_group, and Cell type.

EIF4A1 DDX5 RPS9

7.91e-04198413b3488e916fff9a4ff62eb897d3783c93296dbd65
ToppCell356C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

EIF4A2 DDX5 RPS9

7.91e-041984130f25a3bf2af543267b43e56064ad06dfc18c7bd7
ToppCellMultiple_Sclerosis|World / Disease, Lineage and Cell Type

EIF4A2 DDX5 RPS9

7.91e-0419841346728bb03f4b0d30ae9b62d984a6c2d00cfd370a
ToppCellBasal-basal-7|World / Class top

EIF4A1 DDX5 RPS9

7.91e-04198413240fe56b41b9435e62c66ac7161ef51f89e73e44
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A3 SHH MAGI3

7.91e-04198413c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellCOVID-19-Heart-Mito_EC|Heart / Disease (COVID-19 only), tissue and cell type

MRPL41 RPS9 KIF1C

7.91e-041984133cc34b5d333abba11ab846c26fb4477051958465
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

COL4A3 SHH MAGI3

7.91e-041984131851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_1|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E PRDM8 CHD3

7.91e-04198413d81f35c0066558ff96dd06f58fca72cd82e681e8
ToppCellCV-Severe-2|Severe / Virus stimulation, Condition and Cluster

MRPL15 SNRPD1 EIF4A1

7.91e-04198413254659bb53dc2511c714295c2df1ab1fddb2f867
ToppCellCOVID_vent-Lymphocytic-T_cell-CD4+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

CHD3 EIF4A2 DDX5

7.91e-0419841358f208b76cb0adcecdf632d92f92833a06f9bf71
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-IPC_like|1_mon / Sample Type, Dataset, Time_group, and Cell type.

EIF4A1 DDX5 RPS9

7.91e-041984136d99901d4df24eb3c5cca80afd9a81eb7ee8fcf1
ToppCellCD8+_Memory_T_cell-FLU-2|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SNRPD1 HAGHL TGFBR3L

7.91e-041984139813578a58cdedf68b57a0a5e3cf190c9c25a4cd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

PRDM8 CHD3 EIF4A2

8.03e-041994131b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellEnterocyte_Progenitors|World / shred on cell type and cluster

SNRPD1 EIF4A1 RPS9

8.03e-04199413776bcc887927dea9ebd76ec4338ce2225c319c2c
ToppCell(2)_B_cell-(22)_B_cell_memory|(2)_B_cell / shred on Cell_type and subtype

HAGHL DDX5 RPS9

8.03e-04199413c4c8faa458c1a49487e13667e68bfb1b4b7759b5
ToppCellCD8+_Memory_T_cell-CV-2|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MRPL15 SNRPD1 EIF4A1

8.03e-041994131e33d8e2e0d6a54ef6e2e13f986e19fd209275a8
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SNRPD1 EIF4A1 EIF4A2

8.03e-0419941362936fb64b33f7ad671f9c610bed665f17d3145e
ToppCellTransverse-T_cell-Th1|T_cell / Region, Cell class and subclass

PPP1R15B EIF4A2 DDX5

8.03e-041994139271d9d36ffe1c169049d4340258f366916adfaf
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MRPL15 SNRPD1 RPS9

8.03e-041994130dbeefd99cd1a4d86ee698efbbd75f24dc74fb8c
ToppCellCV-Moderate-2|CV / Virus stimulation, Condition and Cluster

MRPL15 SNRPD1 EIF4A1

8.03e-041994132d98424a5247e87f98095c11fb945289092a9d75
ToppCellmetastatic_Lymph_Node-B_lymphocytes-Follicular_B_cells|B_lymphocytes / Location, Cell class and cell subclass

EIF4A2 DDX5 RPS9

8.03e-0419941386e9582126ab6e219015a685c42f946ee163db15
ToppCellBasal-basal-10|World / Class top

EIF4A1 DDX5 RPS9

8.03e-041994134fadfc58102b21bf9db9d0092f3437aa78fddd99
ToppCellCV-Moderate-2|Moderate / Virus stimulation, Condition and Cluster

MRPL15 SNRPD1 EIF4A1

8.03e-0419941370d6f2a328eec4cb2cecb7cd85859fba9e15c9c8
ToppCellVE-CD8-CD8_2|VE / Condition, Cell_class and T cell subcluster

HAGHL EIF4A2 RPS9

8.03e-04199413014fff8a0ebfda094a6ad76ddc0131e12a313394
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

PRDM8 CHD3 EIF4A2

8.03e-041994134bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

SNRPD1 EIF4A1 EIF4A2

8.03e-04199413f53e0e4c34e6aec81ab07593aa11e045ba04df06
ToppCell18|World / Age, Tissue, Lineage and Cell class

COL11A2 EIF4A2 DDX5

8.03e-04199413ef043232ee028778b8ddb92aeed7584e2bf586d5
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

CACNA1E PRDM8 TCEAL5

8.14e-04200413e9eb348a66011d8aace4331f84690ae27cb0d061
ComputationalNeighborhood of JUND

LSM14A EIF4A2 DDX5

2.86e-0464223MORF_JUND
ComputationalNeighborhood of CCNI

LSM14A EIF4A1 EIF4A2

7.30e-0488223MORF_CCNI
ComputationalGenes in the cancer module 81.

EIF4A1 EIF4A2

7.43e-0420222MODULE_81
ComputationalGenes in the cancer module 115.

EIF4A1 EIF4A2

1.36e-0327222MODULE_115
ComputationalGenes in the cancer module 318.

CHD3 DDX5

1.46e-0328222MODULE_318
ComputationalGenes in the cancer module 229.

EIF4A2 DDX5

1.79e-0331222MODULE_229
ComputationalNeighborhood of CSNK1A1

CHTOP PPP1R15B

2.42e-0336222GCM_CSNK1A1
ComputationalTranslation factors.

EIF4A1 EIF4A2

2.55e-0337222MODULE_149
ComputationalNeighborhood of EIF4A2

LSM14A EIF4A2 DDX5

2.67e-03138223MORF_EIF4A2
ComputationalNeighborhood of ACTG1

EIF4A1 EIF4A2 RPS9

2.67e-03138223MORF_ACTG1
DiseaseMacrocephaly

CACNA1E CHD3

8.35e-0511372C0221355
DiseaseConnective Tissue Diseases

ZNF469 COL11A2

1.18e-0413372C0009782
DiseaseSezary Syndrome

KMT2C CHD3

5.26e-0427372C0036920
DiseaseGlobal developmental delay

PRR12 CACNA1E CHD3

6.22e-04133373C0557874
DiseaseTakayasu arteritis

PRRC2A PRRT4 RPS9

8.48e-04148373EFO_1001857
Diseasenasopharynx carcinoma (is_marker_for)

KMT2C SNRPD1

1.34e-0343372DOID:9261 (is_marker_for)
Diseasehematocrit

SREBF1 COL4A3 PRR12 RGS14 PRDM8 CHD3

1.49e-031011376EFO_0004348
Diseasemacula measurement

COL4A3 SHH CHD3

1.71e-03189373EFO_0008375
DiseaseIntellectual Disability

PRR12 CACNA1E KMT2C CHD3

2.31e-03447374C3714756

Protein segments in the cluster

PeptideGeneStartEntry
GHYRRRRRGGPGPGM

CACNA1E

2281

Q15878
KGKRGTLGFPGRAGR

COL4A3

1026

Q01955
RGFDRFGPDGTGRKR

AKAP8

291

O43823
RVQGFRRRGGKAGGF

AHDC1

661

Q5TGY3
RTHRPGGKRGRLAGG

CCDC74A

141

Q96AQ1
RRGKRVGGEGTGFGV

HAGHL

206

Q6PII5
VGRRFPAGGKRGRGA

NOP9

11

Q86U38
RGSGFPGKRRPRGAG

KMT2C

886

Q8NEZ4
RGPRGFGFSLRGGKE

MAGI3

1026

Q5TCQ9
RGPERRGGKRDRGQG

DDX54

791

Q8TDD1
GRDRGFGAPRFGGSR

DDX5

11

P17844
YIHRIGRGGRFGRKG

EIF4A1

356

P60842
RRGRAGADGARGMPG

COL11A2

536

P13942
GGRGGGLRRPPARFV

KIF1C

956

O43896
RGGRGRFGIRRDGPM

LSM14A

276

Q8ND56
FTAPRGFRGGFRGGR

LSM14A

431

Q8ND56
FNGAGGGIGAPRRRA

GGN

366

Q86UU5
TGRGGRQKNRFGLPG

UPF1

1026

Q92900
RRLGARGGGKGRKGP

CD2BP2

176

O95400
AGPGGARRTVRVYKG

GRID2IP

271

A4D2P6
GGSEYGTGPGRKRRR

CHD3

91

Q12873
IGRGGRFGRKGVAIN

EIF4A2

361

Q14240
GRCGGRRAAKLGPGR

SDK1

66

Q7Z5N4
LRSPYGGGRPGRVKR

RPS9

161

P46781
GPRSFRGRKGRGAKG

MRPL41

26

Q8IXM3
RGRKGRGAKGIGFLT

MRPL41

31

Q8IXM3
GRKCGRGHKGERQRG

MRPL15

46

Q9P015
GLACGPGRGFGKRRH

SHH

21

Q15465
RRGRGGRVTFPGGLK

TGFBR3L

16

H3BV60
GARKTRAGGRGRGRG

PNMA8B

556

Q9ULN7
RAGGRGRGRGVTPEK

PNMA8B

561

Q9ULN7
GAGLVGGRGRFVERP

PRDM8

326

Q9NQV8
RGFRGTYGGRGRGAR

PRRC2A

1036

P48634
GVGRKVRRPAGVRGH

FTSJ3

806

Q8IY81
RGRGRGRGRKAEEAG

PRR12

1201

Q9ULL5
GGSRKRLGPRAGFRF

PPP1R15B

6

Q5SWA1
LRRRAGPGGKGGAVA

SREBF1

1061

P36956
GGRAVAPRMGLRRGG

CHTOP

141

Q9Y3Y2
APRMGLRRGGVRGRG

CHTOP

146

Q9Y3Y2
GVRGVRGGGRGQKDL

TCEAL5

186

Q5H9L2
GRRRRAGAPLGGSGF

PRRT4

521

C9JH25
KREAVAGRGRGRGRG

SNRPD1

91

P62314
GGRPLRKSFRRELGG

RGS14

236

O43566
LGARGFPGGRRSGRD

nan

156

Q8N1X5
PGFRGRRGRGEKRKE

ZNF469

1081

Q96JG9
GKLVGRFGGRGATDR

TRIM3

606

O75382