Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	mesenchyme migration	ACTA1 ACTA2 ACTC1	2.42e-06	5	130	3	GO:0090131
Domain	ACTINS_1	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.66e-10	8	131	5	PS00406
Domain	Actin_CS	ACTA1 ACTA2 ACTB ACTC1 ACTG1	6.45e-08	16	131	5	IPR004001
Domain	ACTINS_2	ACTA1 ACTA2 ACTB ACTC1 ACTG1	9.09e-08	17	131	5	PS00432
Domain	Actin/actin-like_CS	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.25e-07	18	131	5	IPR020902
Domain	ACTINS_ACT_LIKE	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.69e-07	19	131	5	PS01132
Domain	Actin	ACTA1 ACTA2 ACTB ACTC1 ACTG1	2.31e-06	31	131	5	IPR004000
Domain	Actin	ACTA1 ACTA2 ACTB ACTC1 ACTG1	2.31e-06	31	131	5	PF00022
Domain	ACTIN	ACTA1 ACTA2 ACTB ACTC1 ACTG1	2.31e-06	31	131	5	SM00268
Domain	ASH	ASPM HYDIN	4.88e-05	2	131	2	IPR031549
Domain	ASH	ASPM HYDIN	4.88e-05	2	131	2	PF15780
Domain	TILa_dom	TECTA FCGBP	1.46e-04	3	131	2	IPR025615
Domain	TILa	TECTA FCGBP	1.46e-04	3	131	2	PF12714
Domain	EGF	TECTA SVEP1 CELSR3 CELSR2 NRXN1 TNXB	2.63e-04	126	131	6	PF00008
Domain	CABIT	GAREM2 GAREM1	2.90e-04	4	131	2	PF12736
Domain	CABIT_dom	GAREM2 GAREM1	2.90e-04	4	131	2	IPR025946
Domain	EGF-like_dom	TECTA ADAM12 SVEP1 FCGBP CELSR3 CELSR2 NRXN1 TNXB	3.77e-04	249	131	8	IPR000742
Domain	-	SVEP1 CELSR3 CELSR2 NRXN1 PAPPA	5.50e-04	95	131	5	2.60.120.200
Domain	HormR	VIPR1 CELSR3 CELSR2	6.93e-04	25	131	3	SM00008
Domain	HRM	VIPR1 CELSR3 CELSR2	9.72e-04	28	131	3	PF02793
Domain	APC_su10/DOC_dom	CUL9 ZZEF1	1.00e-03	7	131	2	IPR004939
Domain	eIF5C	EIF4G2 BZW1	1.00e-03	7	131	2	SM00515
Domain	DOC	CUL9 ZZEF1	1.00e-03	7	131	2	PS51284
Domain	ANAPC10	CUL9 ZZEF1	1.00e-03	7	131	2	PF03256
Domain	W2	EIF4G2 BZW1	1.00e-03	7	131	2	PF02020
Domain	W2	EIF4G2 BZW1	1.00e-03	7	131	2	PS51363
Domain	APC10	CUL9 ZZEF1	1.00e-03	7	131	2	SM01337
Domain	W2_domain	EIF4G2 BZW1	1.00e-03	7	131	2	IPR003307
Domain	EGF	TECTA SVEP1 FCGBP CELSR3 CELSR2 NRXN1 TNXB	1.36e-03	235	131	7	SM00181
Domain	SAM/pointed	SFMBT1 ETS2 SAMHD1 GAREM2 GAREM1	1.41e-03	117	131	5	IPR013761
Domain	Ubiquitin-rel_dom	RAPGEF4 DDI1 RGL1 UBXN11 BAG6 EPB41L2	1.91e-03	184	131	6	IPR029071
Domain	Rap_GAP	SIPA1L3 RAP1GAP2	2.12e-03	10	131	2	PF02145
Domain	VWC	TECTA CCN4 FCGBP	2.38e-03	38	131	3	SM00214
Domain	LAM_G_DOMAIN	CELSR3 CELSR2 NRXN1	2.38e-03	38	131	3	PS50025
Domain	Rap_GAP_dom	SIPA1L3 RAP1GAP2	2.58e-03	11	131	2	IPR000331
Domain	GAIN_dom_N	CELSR3 CELSR2	2.58e-03	11	131	2	IPR032471
Domain	RAPGAP	SIPA1L3 RAP1GAP2	2.58e-03	11	131	2	PS50085
Domain	GAIN	CELSR3 CELSR2	2.58e-03	11	131	2	PF16489
Domain	GPCR_2_extracellular_dom	VIPR1 CELSR3 CELSR2	2.76e-03	40	131	3	IPR001879
Domain	G_PROTEIN_RECEP_F2_1	VIPR1 CELSR3 CELSR2	2.76e-03	40	131	3	PS00649
Domain	Laminin_G_2	CELSR3 CELSR2 NRXN1	2.76e-03	40	131	3	PF02210
Domain	G_PROTEIN_RECEP_F2_3	VIPR1 CELSR3 CELSR2	2.76e-03	40	131	3	PS50227
Domain	calpain_III	CAPN2 CAPN5	3.08e-03	12	131	2	SM00720
Domain	C2_III	CAPN2 CAPN5	3.08e-03	12	131	2	IPR033883
Domain	C8	TECTA FCGBP	3.08e-03	12	131	2	PF08742
Domain	TIL	TECTA FCGBP	3.08e-03	12	131	2	PF01826
Domain	Calpain_III	CAPN2 CAPN5	3.08e-03	12	131	2	IPR022683
Domain	VWF_dom	TECTA CCN4 FCGBP	3.17e-03	42	131	3	IPR001007
Domain	Calpain_III	CAPN2 CAPN5	3.62e-03	13	131	2	PF01067
Domain	Unchr_dom_Cys-rich	TECTA FCGBP	3.62e-03	13	131	2	IPR014853
Domain	Calpain_domain_III	CAPN2 CAPN5	3.62e-03	13	131	2	IPR022682
Domain	C8	TECTA FCGBP	3.62e-03	13	131	2	SM00832
Domain	LamG	CELSR3 CELSR2 NRXN1	3.62e-03	44	131	3	SM00282
Domain	TIL_dom	TECTA FCGBP	4.20e-03	14	131	2	IPR002919
Domain	Ras_G-nucl-exch_fac_CS	RAPGEF4 RGL1	4.20e-03	14	131	2	IPR019804
Domain	Calpain_cysteine_protease	CAPN2 CAPN5	4.20e-03	14	131	2	IPR022684
Domain	SAM_DOMAIN	SFMBT1 SAMHD1 GAREM2 GAREM1	4.50e-03	95	131	4	PS50105
Domain	ConA-like_dom	SVEP1 RYR1 CELSR3 CELSR2 NRXN1 PAPPA	4.50e-03	219	131	6	IPR013320
Domain	Peptidase_C2	CAPN2 CAPN5	4.83e-03	15	131	2	PF00648
Domain	-	EIF4G2 BZW1	4.83e-03	15	131	2	1.25.40.180
Domain	CysPc	CAPN2 CAPN5	4.83e-03	15	131	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN2 CAPN5	4.83e-03	15	131	2	IPR001300
Domain	MIF4-like	EIF4G2 BZW1	4.83e-03	15	131	2	IPR016021
Domain	CALPAIN_CAT	CAPN2 CAPN5	4.83e-03	15	131	2	PS50203
Domain	7tm_2	VIPR1 CELSR3 CELSR2	5.20e-03	50	131	3	PF00002
Domain	G_PROTEIN_RECEP_F2_2	VIPR1 CELSR3 CELSR2	5.20e-03	50	131	3	PS00650
Domain	ASX_HYDROXYL	SVEP1 CELSR3 CELSR2 NRXN1	5.39e-03	100	131	4	PS00010
Domain	VWF_type-D	TECTA FCGBP	5.49e-03	16	131	2	IPR001846
Domain	VWFD	TECTA FCGBP	5.49e-03	16	131	2	PS51233
Domain	VWD	TECTA FCGBP	5.49e-03	16	131	2	SM00216
Domain	VWD	TECTA FCGBP	5.49e-03	16	131	2	PF00094
Domain	SMAD_FHA_domain	PNKP MKI67 SMAD9	5.80e-03	52	131	3	IPR008984
Domain	EGF_3	ADAM12 SVEP1 CELSR3 CELSR2 NRXN1 TNXB	6.31e-03	235	131	6	PS50026
Domain	EGF-type_Asp/Asn_hydroxyl_site	SVEP1 CELSR3 CELSR2 NRXN1	6.62e-03	106	131	4	IPR000152
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.87e-05	47	99	5	M39829
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCC3 SEMA4B ABCA2 SIPA1L3 RAP1GAP2 CUL9 HUWE1 KDM6B ZZEF1 RYR1 TBC1D24 DIP2A CELSR3 CELSR2 GAREM2 EPOP DOK4 PLA2G4B ZNF516 TMEM268 TIGD3 SENP2 HECTD1 MFSD5 MED13 SDHA TBCD GAREM1 KLHL17	2.17e-16	1105	134	29	35748872
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	9971772
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	10074138
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	1540415
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	11709093
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	12009869
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	23017337
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.71e-12	6	134	5	9841925
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.64e-11	7	134	5	22535526
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.64e-11	7	134	5	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.64e-11	7	134	5	22640593
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.64e-11	7	134	5	17504171
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.64e-11	7	134	5	22465675
Pubmed	Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.37e-11	8	134	5	14694110
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.37e-11	8	134	5	20147394
Pubmed	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.37e-11	8	134	5	23260110
Pubmed	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	9.80e-11	9	134	5	10556093
Pubmed	Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	9.80e-11	9	134	5	8892894
Pubmed	HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	9.80e-11	9	134	5	18775311
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.95e-10	10	134	5	1907279
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.95e-10	10	134	5	1991513
Pubmed	Gelsolin activity controls efficient early HIV-1 infection.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.95e-10	10	134	5	23575248
Pubmed	CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.57e-10	11	134	5	30962377
Pubmed	N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.57e-10	11	134	5	23294842
Pubmed	Quantitative proteomic analysis of lentiviral vectors using 2-DE.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.57e-10	11	134	5	19639585
Pubmed	HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	6.10e-10	12	134	5	23071112
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	COL4A3 ACTA1 ACTA2 ACTB ACTC1 ACTG1	6.31e-10	26	134	6	24742657
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.53e-09	14	134	5	21923909
Pubmed	Regulating the functions of the HIV-1 matrix protein.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.53e-09	14	134	5	17411366
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	KDM5B ABCA2 CFAP91 ANXA7 SIPA1L3 ACTB RAPGEF4 ETS2 RAP1GAP2 BIRC2 CUL9 HUWE1 KDM6B GSK3A STAMBP DIP2A TXNDC15 CELSR3 EIF4G2 HECTD1 MED13 SDHA	4.45e-09	1285	134	22	35914814
Pubmed	Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.70e-09	17	134	5	17360745
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.70e-09	17	134	5	8997639
Pubmed	A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	6.48e-09	18	134	5	24840128
Pubmed	Functional proteomics mapping of a human signaling pathway.	TOM1L2 PNKP ACTB ETS2 ACTG1 HUWE1 ZZEF1 SVEP1 RLF UBXN11 EIF4G2 PAPPA BAG6 TBCD SMAD9	1.02e-08	591	134	15	15231748
Pubmed	Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.97e-08	22	134	5	16526095
Pubmed	Essential and supporting host cell factors for HIV-1 budding.	ACTA1 ACTA2 ACTB ACTC1 ACTG1	2.51e-08	23	134	5	22004035
Pubmed	Human immunodeficiency virus type 1 envelope gp120-induced partial T-cell receptor signaling creates an F-actin-depleted zone in the virological synapse.	ICAM1 ACTA1 ACTB ACTG1	2.62e-08	9	134	4	19710135
Pubmed	Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.	ACTA1 ACTB ACTC1	5.59e-08	3	134	3	1728592
Pubmed	Restricted morphological and behavioral abnormalities following ablation of β-actin in the brain.	ACTA2 ACTB ACTG1	5.59e-08	3	134	3	22403730
Pubmed	The human beta-actin multigene family.	ACTA1 ACTA2 ACTB	5.59e-08	3	134	3	3842206
Pubmed	The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.	ACTA1 ACTB ACTC1	5.59e-08	3	134	3	6641707
Pubmed	Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.	ACTA1 ACTA2 ACTC1	5.59e-08	3	134	3	7780165
Pubmed	Isolation and characterization of full-length cDNA clones for human alpha-, beta-, and gamma-actin mRNAs: skeletal but not cytoplasmic actins have an amino-terminal cysteine that is subsequently removed.	ACTA1 ACTB ACTG1	5.59e-08	3	134	3	6865942
Pubmed	Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.	ACTA1 ACTB ACTC1	5.59e-08	3	134	3	3084797
Pubmed	Defining the membrane proteome of NK cells.	ABCA2 PNKP ANXA7 ICAM1 CYP20A1 ACTB ACTC1 ACTG1 RNF213 HUWE1 MED1 NCAPH DNAJC10 EIF4G2 MKI67 BZW1 BAG6 MFSD5 MED13	1.25e-07	1168	134	19	19946888
Pubmed	Expression of the BMP receptor Alk3 in the second heart field is essential for development of the dorsal mesenchymal protrusion and atrioventricular septation.	ACTA1 ACTC1 MKI67 SMAD9	2.05e-07	14	134	4	23584254
Pubmed	Polymerisation of chemically cross-linked actin:thymosin beta(4) complex to filamentous actin: alteration in helical parameters and visualisation of thymosin beta(4) binding on F-actin.	ACTA1 ACTA2 ACTB	2.23e-07	4	134	3	11812134
Pubmed	The formin-homology-domain-containing protein FHOD1 enhances cell migration.	ACTA1 ACTB ACTG1	2.23e-07	4	134	3	12665555
Pubmed	Actinfilin, a brain-specific actin-binding protein in postsynaptic density.	ACTC1 ACTG1 KLHL17	2.23e-07	4	134	3	12063253
Pubmed	Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line.	ACTA1 ACTB ACTC1	2.23e-07	4	134	3	2201580
Pubmed	The proline-rich domain of tau plays a role in interactions with actin.	ACTA1 ACTB ACTG1	2.23e-07	4	134	3	19895707
Pubmed	Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.	ANXA7 ACTB HUWE1 KDM6B EIF4G2 PAPPA	2.87e-07	69	134	6	32238831
Pubmed	Microtubule associated protein MAP1A is an actin-binding and crosslinking protein.	ACTA1 ACTB ACTG1	5.56e-07	5	134	3	7820861
Pubmed	D186/D190 is an allele-dependent determinant of HIV-1 Nef function.	ACTA1 ACTA2 ACTB	5.56e-07	5	134	3	27560372
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ABCA2 CUL9 THSD7B CELSR3 NRXN1 HECTD1 MED13	7.67e-07	130	134	7	12421765
Pubmed	Mammalian CAP interacts with CAP, CAP2, and actin.	ACTB ACTG1 BAG6	1.11e-06	6	134	3	8761950
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	SIPA1L3 CAPN2 BIRC2 CUL9 ZZEF1 MKI67 HECTD1 BAG6	1.80e-06	212	134	8	33853758
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTA2 ACTC1	1.94e-06	7	134	3	9384381
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	ACTA1 ACTA2 ACTC1	1.94e-06	7	134	3	30289203
Pubmed	Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.	ACTA1 ACTA2 ACTC1	3.09e-06	8	134	3	20096780
Pubmed	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.	ACTA1 ACTA2 ACTC1	4.62e-06	9	134	3	12297046
Pubmed	Analysis of lipid pathway genes indicates association of sequence variation near SREBF1/TOM1L2/ATPAF2 with dementia risk.	TOM1L2 ABCA2 MLXIPL CELSR2	4.64e-06	29	134	4	20167577
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	COL4A3 CACNA1C FLT3 ASIC2 ACTA1 PTPRB NRXN1	4.77e-06	171	134	7	20201926
Pubmed	Drebrin, an actin-binding protein, is required for lens morphogenesis and growth.	ACTA2 ACTB MKI67	6.58e-06	10	134	3	33896079
Pubmed	Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.	ACTA1 ACTA2 ACTC1	6.58e-06	10	134	3	21749862
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ABCA2 KDM6B ZZEF1 NCAPH TBC1D24 LRRC47 CELSR3 TSR1 ZNF516 CAPRIN2 MED13	6.94e-06	529	134	11	14621295
Pubmed	Proteomic analysis reveals novel binding partners of MIP-T3 in human cells.	ACTA1 ACTB ACTC1 ACTG1	8.93e-06	34	134	4	20391533
Pubmed	FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.	ACTA1 ACTA2 ACTC1	9.02e-06	11	134	3	22207710
Pubmed	Smooth and cardiac muscle-selective knock-out of Kruppel-like factor 4 causes postnatal death and growth retardation.	ACTA2 ACTC1 MKI67	9.02e-06	11	134	3	20439457
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	ACTA1 ACTA2 ACTB ACTC1 ACTG1 MED1 TSR1 MKI67	1.09e-05	271	134	8	32433965
Pubmed	SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.	ACTA1 ACTA2 ACTC1	1.20e-05	12	134	3	31042497
Pubmed	Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice.	ICAM1 ACTA2 MKI67	1.20e-05	12	134	3	20223757
Pubmed	Beta- and gamma-cytoplasmic actins are required for meiosis in mouse oocytes.	ACTB ACTG1	1.47e-05	2	134	2	21778137
Pubmed	De novo mutations in the actin genes ACTB and ACTG1 cause Baraitser-Winter syndrome.	ACTB ACTG1	1.47e-05	2	134	2	22366783
Pubmed	Human leukocyte antigen-B-associated transcript 3 is released from tumor cells and engages the NKp30 receptor on natural killer cells.	NCR3 BAG6	1.47e-05	2	134	2	18055229
Pubmed	Prenatal presentation and diagnosis of Baraitser-Winter syndrome using exome sequencing.	ACTB ACTG1	1.47e-05	2	134	2	32588558
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	1.47e-05	2	134	2	20706863
Pubmed	Baraitser-Winter cerebrofrontofacial syndrome.	ACTB ACTG1	1.47e-05	2	134	2	27625340
Pubmed	Molecular analysis of 23 Pakistani families with autosomal recessive primary microcephaly using targeted next-generation sequencing.	ASPM WDR62	1.47e-05	2	134	2	27784895
Pubmed	A soluble fragment of the tumor antigen BCL2-associated athanogene 6 (BAG-6) is essential and sufficient for inhibition of NKp30 receptor-dependent cytotoxicity of natural killer cells.	NCR3 BAG6	1.47e-05	2	134	2	24133212
Pubmed	Chromosomal localization of Celsr2 and Celsr3 in the mouse; Celsr3 is a candidate for the tippy (tip) lethal mutant on chromosome 9.	CELSR3 CELSR2	1.47e-05	2	134	2	10790539
Pubmed	Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function.	NCR3 BAG6	1.47e-05	2	134	2	18852879
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	1.47e-05	2	134	2	3023046
Pubmed	Isolation of cDNA clones for mouse cytoskeletal gamma-actin and differential expression of cytoskeletal actin mRNAs in mouse cells.	ACTB ACTG1	1.47e-05	2	134	2	3221869
Pubmed	ACTB and SDHA Are Suitable Endogenous Reference Genes for Gene Expression Studies in Human Astrocytomas Using Quantitative RT-PCR.	ACTB SDHA	1.47e-05	2	134	2	30259794
Pubmed	Nucleotide sequences of the rabbit alpha-smooth-muscle and beta-non-muscle actin mRNAs.	ACTA2 ACTB	1.47e-05	2	134	2	1555776
Pubmed	Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.	ACTA1 ACTC1	1.47e-05	2	134	2	3075543
Pubmed	Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension.	ACTB ACTG1	1.47e-05	2	134	2	21502360
Pubmed	The evolution and complexity of the genes encoding the cytoskeletal proteins of human epidermal cells.	ACTB ACTG1	1.47e-05	2	134	2	6686106
Pubmed	Actin amino-acid sequences. Comparison of actins from calf thymus, bovine brain, and SV40-transformed mouse 3T3 cells with rabbit skeletal muscle actin.	ACTB ACTG1	1.47e-05	2	134	2	213279
Pubmed	The First Korean Case of Baraitser-Winter Cerebro-Fronto-Facial Syndrome with a Novel Mutation in ACTB Diagnosed Via Targeted Gene Panel Sequencing and Literature Review.	ACTB ACTG1	1.47e-05	2	134	2	33334799
Pubmed	β-Actin specifically controls cell growth, migration, and the G-actin pool.	ACTB ACTG1	1.47e-05	2	134	2	21900491
Pubmed	Beta and gamma-cytoplasmic actins display distinct distribution and functional diversity.	ACTB ACTG1	1.47e-05	2	134	2	19638415
Interaction	TOP3B interactions	ABCC3 SEMA4B ABCA2 SIPA1L3 RAP1GAP2 ACTG1 CUL9 HUWE1 KDM6B ZZEF1 RYR1 TBC1D24 DIP2A CELSR3 CELSR2 GAREM2 EPOP DOK4 LRRC31 PLA2G4B ZNF516 TMEM268 TIGD3 SENP2 HECTD1 MFSD5 MED13 SDHA TBCD GAREM1 KLHL17	5.30e-09	1470	133	31	int:TOP3B
Interaction	TMSB4X interactions	ANXA7 ACTA1 ACTA2 ACTB ACTC1 ACTG1 MED1 MKI67	5.66e-08	80	133	8	int:TMSB4X
Interaction	DNASE1 interactions	ACTA1 ACTA2 ACTB ACTG1	6.25e-08	7	133	4	int:DNASE1
Interaction	POTEJ interactions	ACTA1 ACTA2 ACTB ACTC1 ACTG1 CUL9	1.17e-06	52	133	6	int:POTEJ
Interaction	ERRFI1 interactions	ACTA1 ACTA2 ACTB ACTC1 ACTG1 MFSD5 HYDIN	7.01e-06	107	133	7	int:ERRFI1
Interaction	LRRFIP1 interactions	LUC7L3 ACTB ACTC1 ACTG1 NCAPH TSR1 BZW1 HECTD1	8.07e-06	153	133	8	int:LRRFIP1
Interaction	PTMA interactions	VIPR1 CAPN2 ACTA2 ACTB ACTC1 ACTG1 GSK3A MKI67 BAG6	1.17e-05	212	133	9	int:PTMA
Interaction	ACTG2 interactions	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.75e-05	49	133	5	int:ACTG2
Interaction	PFN3 interactions	ACTA2 ACTB ACTC1	3.26e-05	10	133	3	int:PFN3
Interaction	LCOR interactions	ABCA2 ACTB SAMHD1 GSK3A EPOP ZNF516 EIF4G2 MED13 SDHA	3.34e-05	242	133	9	int:LCOR
Interaction	PHACTR2 interactions	ACTA2 ACTB ACTC1 ACTG1	3.79e-05	29	133	4	int:PHACTR2
Interaction	SCIN interactions	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.02e-05	58	133	5	int:SCIN
Interaction	WASH8P interactions	ACTA2 ACTB ACTC1	4.46e-05	11	133	3	int:WASH8P
Interaction	TWF2 interactions	CAPN2 ACTA2 ACTB ACTC1 ACTG1 ITGA2B	5.29e-05	100	133	6	int:TWF2
Interaction	POTEI interactions	ACTA1 ACTA2 ACTB ACTC1 ACTG1 EPB41L2	6.95e-05	105	133	6	int:POTEI
Interaction	KLHL17 interactions	RAPGEF4 ACTC1 ACTG1 KLHL17	7.21e-05	34	133	4	int:KLHL17
Interaction	CAP2 interactions	ACTA1 ACTA2 ACTB ACTC1 ACTG1	7.51e-05	66	133	5	int:CAP2
Interaction	PCYT1B interactions	ACTA1 ACTA2 ACTB	7.66e-05	13	133	3	int:PCYT1B
Interaction	PSMA1 interactions	SFMBT1 CAPN2 ACTB CUL9 EXOSC5 DDI1 HUWE1 KDM6B LRRC47 UBXN11 RAD54B BZW1	8.23e-05	480	133	12	int:PSMA1
Interaction	PFN2 interactions	ACTA2 ACTB ACTC1 ACTG1 BIRC2 KDM6B NAE1	9.03e-05	159	133	7	int:PFN2
Interaction	ABRA interactions	ACTA1 ACTA2 ACTB ACTC1	9.07e-05	36	133	4	int:ABRA
Interaction	DUSP10 interactions	ACTA2 ACTB ACTC1 SAMHD1 DNAJC10	1.07e-04	71	133	5	int:DUSP10
Interaction	RNF123 interactions	DNAH2 ACTG1 RNF213 SAMHD1 HUWE1 ZZEF1 RYR1 USP19 LRRC47 CCN4 DIP2A EXOC3L4 BAG6 EPB41L2 SDHA SMAD9	1.08e-04	824	133	16	int:RNF123
Interaction	EIF3H interactions	LUC7L3 ICAM1 ACTB NCAPH LRRC47 EIF4G2 MKI67 HECTD1 BAG6	1.09e-04	282	133	9	int:EIF3H
Interaction	FBXO40 interactions	ACTA2 ACTB ACTC1	1.21e-04	15	133	3	int:FBXO40
Interaction	NAA80 interactions	ACTA2 ACTB ACTC1	1.21e-04	15	133	3	int:NAA80
Interaction	WIPF3 interactions	ACTB ACTC1 ACTG1	1.48e-04	16	133	3	int:WIPF3
Interaction	FLII interactions	MED20 ACTB ACTC1 ACTG1 NCAPH LRRC31 TSR1 BZW1 HECTD1	1.64e-04	298	133	9	int:FLII
Interaction	REG3A interactions	ACTA2 ACTB ACTC1	1.79e-04	17	133	3	int:REG3A
Interaction	OSTM1 interactions	ACTA2 BIRC2 RNF213 EXOSC5 TBCD	1.88e-04	80	133	5	int:OSTM1
Cytoband	3p21.31	CDCP1 USP19 CELSR3 PRSS42P INKA1	1.18e-05	100	134	5	3p21.31
Cytoband	Ensembl 112 genes in cytogenetic band chr3p21	SFMBT1 CDCP1 USP19 CELSR3 PRSS42P INKA1	3.48e-04	316	134	6	chr3p21
Cytoband	Ensembl 112 genes in cytogenetic band chr17p13	DNAH2 RAP1GAP2 KDM6B ZZEF1 TSR1 TMEM102	5.61e-04	346	134	6	chr17p13
Cytoband	19q13.1	EXOSC5 RYR1 FCGBP	5.71e-04	55	134	3	19q13.1
Cytoband	19q13.13	SIPA1L3 IFNL2	8.66e-04	15	134	2	19q13.13
GeneFamily	Actins	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.15e-11	6	84	5	929
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR3 CELSR2	6.38e-05	3	84	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR3 CELSR2	6.38e-05	3	84	2	1189
GeneFamily	Cyclins\|Mediator complex	MED20 MED1 MED13	4.77e-04	33	84	3	1061
GeneFamily	C2 domain containing\|Calpains	CAPN2 CAPN5	2.15e-03	15	84	2	975
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	FLT3 ICAM1 ITGA2B CDCP1 NCR3 TLR10 MELTF	2.38e-03	394	84	7	471
Coexpression	RIGGI_EWING_SARCOMA_PROGENITOR_DN	KCTD4 CHI3L1 CDCP1 ADAM12 SVEP1 CCN4 MELTF ASPM	7.90e-06	196	134	8	M13256
Coexpression	GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_UP	COL4A3 ICAM1 ACTA1 ETS2 ACTC1 MED1 MELTF AOC3	9.16e-06	200	134	8	M8203
Coexpression	GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_DN	VIPR1 CAPN2 RAPGEF4 RAP1GAP2 TECTA ADAM12 RAD54B	2.91e-05	171	134	7	M8820
Coexpression	DARWICHE_PAPILLOMA_RISK_LOW_DN	ICAM1 ACTA1 ACTA2 SAMHD1 DIP2A DOK4 BAG6	3.02e-05	172	134	7	M1134
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 AOC3	1.98e-05	26	133	4	gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 AOC3	2.68e-05	28	133	4	gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
ToppCell	Control-Control-Myeloid-immature_Neutrophil\|Control / Disease, condition lineage and cell class	SEMA4B CHI3L1 NCAPH NSDHL RLF CENPI MKI67 ASPM EPB41L2	1.02e-08	200	134	9	118321ac443feb42aee171baccfc4610f00a8822
ToppCell	RSV-Healthy-2\|Healthy / Virus stimulation, Condition and Cluster	ACTB RAP1GAP2 NCAPH KIAA0825 RAD54B MKI67 ASPM WDR62	6.13e-08	175	134	8	c47440c0b0513e67fe13b85f10dd8a8d42d0e9a3
ToppCell	RSV-Healthy-2\|RSV / Virus stimulation, Condition and Cluster	ACTB RAP1GAP2 NCAPH KIAA0825 RAD54B MKI67 ASPM WDR62	6.13e-08	175	134	8	0e97189585b7afaf3bd622c3ef10c86412393829
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM EPB41L2	9.02e-08	184	134	8	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SEMA4B CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM EPB41L2	9.02e-08	184	134	8	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	SEMA4B CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM EPB41L2	9.02e-08	184	134	8	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SEMA4B CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM EPB41L2	9.02e-08	184	134	8	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SEMA4B CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM EPB41L2	9.02e-08	184	134	8	d31d4116d1d196633784863781fa45673607a421
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	SEMA4B ANKRD36C CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM	9.02e-08	184	134	8	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCell	Control-immature_Neutrophil\|Control / Disease condition and Cell class	SEMA4B ANKRD36C CHI3L1 NCAPH NSDHL CENPI MKI67 ASPM	9.02e-08	184	134	8	2fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SAMHD1 NCAPH RYR1 FCGBP CENPI MKI67 ASPM WDR62	1.02e-07	187	134	8	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF4 ANKRD36C NCAPH PTPRB CENPI MKI67 ASPM WDR62	1.15e-07	190	134	8	31de1727822e9818652946dfb962daee77ffad68
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells-Platelet\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	ABCC3 PADI4 CAPN2 ACTB GPX4 ACTG1 ITGA2B UBXN11	1.30e-07	193	134	8	06ddaeb2fd32895181e23f3f1bb3e9103e79752c
ToppCell	COVID-19-lung-Proliferative_fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CACNA1C NCAPH ADAM12 CCN4 CENPI MKI67 ASPM WDR62	1.47e-07	196	134	8	2ce8a787f2731faa913d20342d73041d59468f27
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C ACTA2 NEU3 CELSR2 CAPRIN2 AOC3 SMAD9	8.86e-07	171	134	7	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1C ACTA2 NEU3 CELSR2 CAPRIN2 AOC3 SMAD9	8.86e-07	171	134	7	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FLT3 SAMHD1 NCAPH CENPI MKI67 ASPM WDR62	8.86e-07	171	134	7	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CACNA1C UPK3B FCGBP MKI67 ASPM WDR62 GAREM1	8.86e-07	171	134	7	0eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_2\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CACNA1C UPK3B FCGBP MKI67 ASPM WDR62 GAREM1	1.03e-06	175	134	7	bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 CFAP91 CRYGN CAPRIN2 AOC3 HYDIN LRRC74B	1.12e-06	177	134	7	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	SEMA4B ANKRD36C NCAPH NSDHL CENPI EPB41L2 TMEM63A	1.45e-06	184	134	7	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH SVEP1 CENPI RAD54B MKI67 ASPM WDR62	1.61e-06	187	134	7	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH SVEP1 CENPI RAD54B MKI67 ASPM WDR62	1.61e-06	187	134	7	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 ABCC3 RAP1GAP2 RNF213 CDCP1 HYDIN GAREM1	1.73e-06	189	134	7	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 ABCC3 RAP1GAP2 RNF213 CDCP1 HYDIN GAREM1	1.73e-06	189	134	7	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 ABCC3 ASIC2 RAP1GAP2 RNF213 HYDIN GAREM1	2.06e-06	194	134	7	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	ABCC3 PADI4 ACTB GPX4 ACTG1 ITGA2B EIF4G2	2.20e-06	196	134	7	21ad9a63242e33038f9f531dd4074a5a9304ed62
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LUC7L3 ETS2 SAMHD1 SVEP1 PAPPA TNXB EPB41L2	2.43e-06	199	134	7	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ANKRD36C NCAPH CENPI RAD54B MKI67 ASPM WDR62	2.52e-06	200	134	7	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PADI4 ESS2 ACTA1 CHI3L1 TDRD1 CENPI	4.77e-06	143	134	6	9836a040a2ebcf6f05431e658a7b8fd566621452
ToppCell	PBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PADI4 ESS2 ACTA1 CHI3L1 TDRD1 CENPI	4.77e-06	143	134	6	4622c221b5d2d4cd4f37e4f81662e073924e1507
ToppCell	facs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 ACTA2 RAP1GAP2 CHI3L1 KDM6B CELSR3	6.28e-06	150	134	6	6e806a028c0519489151c181d9907e05289e27e0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PADI4 NCAPH CENPI MKI67 ASPM WDR62	7.57e-06	155	134	6	969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	COL4A3 ACTB TLR10 EXOC3L4 TIGD3 INKA1	7.86e-06	156	134	6	4e4b94580969a9736ca28df79715535a4bd1f9b2
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCC3 SEMA4B CHI3L1 ADAM12 SVEP1 CCN4	8.45e-06	158	134	6	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH CENPI RAD54B MKI67 ASPM WDR62	1.01e-05	163	134	6	3f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	RAPGEF4 ADAM12 NCR3 ASPM SMAD9 KLHL17	1.20e-05	168	134	6	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH CENPI RAD54B MKI67 ASPM WDR62	1.24e-05	169	134	6	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CFAP91 NCAPH CENPI RAD54B MKI67 WDR62	1.24e-05	169	134	6	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH CENPI RAD54B MKI67 ASPM WDR62	1.28e-05	170	134	6	21bfe070e63722672176052b386167ea4c3dc4e5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH CCN4 CENPI MKI67 ASPM WDR62	1.33e-05	171	134	6	b0373ed8283ee1792b6a490bff93906546978593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH CCN4 CENPI MKI67 ASPM WDR62	1.33e-05	171	134	6	b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCell	367C-Lymphocytic-NK_cells-Proliferating_NK_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	NCAPH NCR3 CENPI MKI67 ASPM WDR62	1.33e-05	171	134	6	4ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA1 ACTA2 ACTB ACTC1 EPOP AOC3	1.42e-05	173	134	6	ecbf7167d4bec685e3460d826318544946f5f5c2
ToppCell	10x3'2.3-week_14-16-Myeloid_DC-DC-DC_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLT3 ACTB ACTG1 SAMHD1 CELSR3 PLA2G4B	1.42e-05	173	134	6	a361474ad6f058bb3d3f9671bae697205535090b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA1 ACTA2 ACTB ACTC1 EPOP AOC3	1.42e-05	173	134	6	b8dc978c52de64afba21ff6cb32e79f07167448e
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP91 CCN4 NRXN1 AOC3 MKI67 ASPM	1.51e-05	175	134	6	fa16c6ba08dc0cc22e8cf049db0577811d080df6
ToppCell	COVID-19_Mild-Neu_3\|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients	CDCP1 MIR1915HG CEP68 RGL1 CAPRIN2 ASB1	1.56e-05	176	134	6	2049767fd591045cfcf5b1071d80798e52843f27
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 AOC3 MKI67 ASPM TIGD3	1.56e-05	176	134	6	45c6983ab671b0f306e7390320bd84f848e474cc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	RAPGEF4 ETS2 RGL1 PTPRB AOC3 INKA1	1.56e-05	176	134	6	64e426f5e84884ce2c29acf6f4b958962a63927f
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	CACNA1C ACTA2 ADAM12 SVEP1 CCN4 AOC3	1.66e-05	178	134	6	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL4A3 RAPGEF4 ADAM12 SVEP1 CCN4 PAPPA	1.66e-05	178	134	6	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SIPA1L3 NCAPH RYR1 DIP2A RAD54B MKI67	1.72e-05	179	134	6	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NCAPH CENPI RAD54B MKI67 ASPM WDR62	1.77e-05	180	134	6	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	E18.5-samps-Mesenchymal-Pericyte\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ACTA2 CCN4 NRXN1 AOC3 SLC35F6 EPB41L2	1.77e-05	180	134	6	0b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|normal_Lung / Location, Cell class and cell subclass	RAPGEF4 TLR10 FCGBP GAREM2 MKI67 WDR62	1.83e-05	181	134	6	b55dbcfae8c92d322071906831489830a22239b9
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPH CELSR3 CENPI RAD54B MKI67 ASPM	1.89e-05	182	134	6	bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 SAMHD1 SVEP1 CCN4 CRYGN EPB41L2	1.89e-05	182	134	6	44764676ed3f51ba171ce63f669390392fa50a43
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	RAPGEF4 TLR10 FCGBP GAREM2 MKI67 WDR62	1.89e-05	182	134	6	8dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 SAMHD1 SVEP1 CCN4 CRYGN EPB41L2	1.89e-05	182	134	6	d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPH CELSR3 CENPI RAD54B MKI67 ASPM	1.89e-05	182	134	6	0fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CCN4 KIAA0825 TMEM268 AOC3 PAPPA EPB41L2	1.95e-05	183	134	6	5377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	ABCC3 UPRT ANKRD36C TDRD1 FCGBP CAPN5	1.95e-05	183	134	6	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 DNAJC10 AOC3 MKI67 ASPM	2.01e-05	184	134	6	d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th1\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ACTB ACTG1 RNF213 ADAM12 NCR3 ASPM	2.07e-05	185	134	6	326c8b6ea0e9140616d7b867db1385b980dc3678
ToppCell	facs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPH CENPI RAD54B MKI67 ASPM WDR62	2.13e-05	186	134	6	9feef5936985e936b3d88f9d1bb012abb6468570
ToppCell	facs-Heart-LA-24m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETS2 ACTG1 KDM6B PTPRB DOK4 INKA1	2.13e-05	186	134	6	f8ed078684ce6d914fd9cb1f0ef4aba36db39b3f
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MED20 FLT3 ADAM12 TLR10 TMEM268 KLHL17	2.13e-05	186	134	6	a558fd00053e7dd6216b01dc8e650c30cee451f1
ToppCell	facs-Heart-LA-24m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETS2 ACTG1 KDM6B PTPRB DOK4 INKA1	2.13e-05	186	134	6	1d08e60d239153c9e5ea42135d702d494d8b42b1
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MED20 FLT3 ADAM12 TLR10 TMEM268 KLHL17	2.13e-05	186	134	6	75b1f342be5d6dbe0e7acd924a0ca75964f6bab0
ToppCell	5'-Airway_Nasal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MED20 FLT3 ADAM12 TLR10 TMEM268 KLHL17	2.13e-05	186	134	6	0c3d195077de7b4c354c127a26116438aef29244
ToppCell	facs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPH CENPI RAD54B MKI67 ASPM WDR62	2.13e-05	186	134	6	89f5b06bc56674af304912d481ac697c7c870904
ToppCell	COVID_non-vent-Myeloid-Dendritic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FLT3 ACTB ETS2 ACTG1 SAMHD1 RGL1	2.20e-05	187	134	6	936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCell	COVID_non-vent-Myeloid-Dendritic-cDC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	FLT3 ACTB ETS2 ACTG1 SAMHD1 RGL1	2.20e-05	187	134	6	55fe4e8b4f301876716c1af15c34d42164f2358e
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 CYP20A1 CCN4 NRXN1 AOC3 EPB41L2	2.26e-05	188	134	6	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 ADAM12 SVEP1 CCN4 TNXB EPB41L2	2.33e-05	189	134	6	71397e993a77d70b2eeede240bdfc7660b558987
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 ADAM12 SVEP1 CCN4 TNXB EPB41L2	2.33e-05	189	134	6	4eea4759520c312bd17a681034d8074e47093d2b
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CYP20A1 CCN4 NRXN1 AOC3 SLC35F6 EPB41L2	2.33e-05	189	134	6	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	facs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPH CENPI RAD54B MKI67 ASPM WDR62	2.33e-05	189	134	6	bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCell	facs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCAPH CENPI RAD54B MKI67 ASPM WDR62	2.33e-05	189	134	6	96f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CYP20A1 CCN4 NRXN1 AOC3 SLC35F6 EPB41L2	2.40e-05	190	134	6	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_Tregs\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ACTA2 ACTB ACTG1 CUL9 SAMHD1 ADAM12	2.40e-05	190	134	6	f69a4733b5d1542ab4d0eb44856f2c5c34c18b9e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C CHI3L1 ADAM12 SVEP1 CCN4 PAPPA	2.40e-05	190	134	6	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 CYP20A1 CCN4 NRXN1 AOC3 EPB41L2	2.40e-05	190	134	6	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells-Platelet\|Megakaryo-cells / Lineage, cell class and subclass	ABCC3 PADI4 CAPN2 ACTB ITGA2B UBXN11	2.55e-05	192	134	6	a061db719d87209b56d074afbdeab37aa0079419
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 ADAM12 SVEP1 CCN4 TNXB EPB41L2	2.55e-05	192	134	6	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL4A3 SAMHD1 SVEP1 PAPPA TNXB EPB41L2	2.55e-05	192	134	6	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	H1299-infected\|H1299 / Cell line, Condition and Strain	LUC7L3 ANKRD36C CAPRIN2 MKI67 ASPM WDR62	2.55e-05	192	134	6	9cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCell	ILEUM-inflamed-(1)_Tregs\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ACTB ACTG1 CUL9 RNF213 SAMHD1 ADAM12	2.55e-05	192	134	6	1fe3417dfd1cf1758fd82c9ac13dbd88bdf0b548
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP91 DNAH2 UBXN11 KIAA0825 HYDIN FYB2	2.62e-05	193	134	6	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	human_hepatoblastoma-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	NCAPH CENPI MKI67 ASPM WDR62 TBCD	2.62e-05	193	134	6	4b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCell	ILEUM-non-inflamed-(3)_MNP-(3)_DC1\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FLT3 ACTB ACTG1 TLR10 NAE1 MKI67	2.62e-05	193	134	6	42775588e788c330aade07e54b208f1c2eea3ab3
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANXA7 GPX4 BIRC2 ADAM12 CEP68 BZW1	2.62e-05	193	134	6	d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCell	10x5'v1-week_14-16-Myeloid_DC-DC-DC2\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLT3 CAPN2 ACTB ACTG1 SAMHD1 TLR10	2.70e-05	194	134	6	a0cfc8c1cdc0722db39170e4417615b6e6b85041
ToppCell	3'_v3-blood-Lymphocytic_NK-Cycling_NK\|blood / Manually curated celltypes from each tissue	NCAPH NCR3 CENPI MKI67 ASPM WDR62	2.70e-05	194	134	6	bf9734abaad603ade2a6a6940918aaf1e1c4e2cd
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 ADAM12 SVEP1 CCN4 TNXB EPB41L2	2.70e-05	194	134	6	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 ADAM12 SVEP1 CCN4 TNXB EPB41L2	2.70e-05	194	134	6	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	(4)_Endothelial_cells-(42)_EC-sinusoidal\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ICAM1 ETS2 RGL1 PTPRB CRYGN INKA1	2.70e-05	194	134	6	4428b472c2042f88eae028b1770767512a515b75
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 ABCC3 RAP1GAP2 RNF213 CDCP1 GAREM1	2.78e-05	195	134	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 SAMHD1 ADAM12 SVEP1 CCN4 EPB41L2	2.78e-05	195	134	6	cad6563cc51d212554152c727fc2c249c6a07e4d
Computational	Muscle genes.	VIPR1 ACTA1 ACTA2 ACTC1 ADAM12 RYR1	3.64e-07	37	84	6	MODULE_512
Computational	Genes in the cancer module 387.	VIPR1 ACTA1 ACTA2 ACTC1 ADAM12 RYR1	2.03e-06	49	84	6	MODULE_387
Computational	Genes in the cancer module 329.	VIPR1 ACTA1 ACTA2 ACTC1 ADAM12 RYR1	2.58e-06	51	84	6	MODULE_329
Computational	Genes in the cancer module 330.	VIPR1 ACTA1 ACTC1 RYR1	6.16e-05	28	84	4	MODULE_330
Drug	3-methylhistidine	CAPN2 ACTA1 ACTA2 ACTB ACTC1 ACTG1 ASPM	3.35e-08	55	134	7	CID000064969
Drug	Nsc687160	ACTA1 ACTA2 ACTB ACTC1 ACTG1	5.28e-08	18	134	5	CID005459290
Drug	tolytoxin	ACTA1 ACTA2 ACTB ACTC1 ACTG1	7.13e-08	19	134	5	CID006440827
Drug	m2-19	ACTA1 ACTA2 ACTB ACTC1 ACTG1	7.13e-08	19	134	5	CID000079129
Drug	manidipine	CACNA1C ICAM1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 RYR1	9.22e-08	95	134	8	CID000004008
Drug	NSC312786	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.24e-07	21	134	5	CID000329495
Drug	AC1L8NVR	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.24e-07	21	134	5	CID000384633
Drug	SIRIUS	COL4A3 ACTA1 ACTA2 ACTB ACTC1 ACTG1 MLXIPL	3.57e-07	77	134	7	CID000091750
Drug	CID5288653	ACTA1 ACTA2 ACTB ACTC1 ACTG1	5.77e-07	28	134	5	CID005288653
Drug	azaspiracid	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.29e-07	30	134	5	CID006451158
Drug	AC1L1HS4	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.16e-06	32	134	5	CID000004267
Drug	dihydrocytochalasin B	ACTA1 ACTA2 ACTB ACTC1 ACTG1 ITGA2B	1.17e-06	58	134	6	CID000003064
Drug	N,N'-p-phenylenedimaleimide	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.59e-06	34	134	5	CID000076765
Drug	1,N6-ethenoadenosine 5'-diphosphate	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.59e-06	34	134	5	CID000001312
Drug	NSC60597	SEMA4B ACTA1 ACTA2 ACTB ACTC1 ACTG1 MED1 SDHA	1.82e-06	140	134	8	CID000003327
Drug	AC1NSKFN	ACTA1 ACTA2 ACTB ACTC1 ACTG1	2.13e-06	36	134	5	CID005311324
Drug	sulphoxide	SFMBT1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 AOC3	2.27e-06	101	134	7	CID000008442
Drug	Ethamsylate [2624-44-4]; Up 200; 15.2uM; HL60; HT_HG-U133A	SIPA1L3 RAP1GAP2 NEU3 ITGA2B TECTA NRXN1 WDR62 TBCD TMEM63A	2.50e-06	196	134	9	2915_UP
Drug	fluorescein isothiocyanate	ICAM1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 NEU3 ITGA2B	2.62e-06	147	134	8	CID000018730
Drug	Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; MCF7; HT_HG-U133A	COL4A3 ICAM1 ACTC1 ITGA2B GSK3A CCN4 PTPRB DOK4 TMEM63A	2.71e-06	198	134	9	4171_UP
Drug	Bephenium hydroxynaphthoate [3818-50-6]; Up 200; 9uM; MCF7; HT_HG-U133A	ABCC3 KDM5B ESS2 ICAM1 ACTA1 SVEP1 DOK4 PAPPA TMEM63A	2.71e-06	198	134	9	5628_UP
Drug	SC-560; Down 200; 10uM; PC3; HT_HG-U133A	SIPA1L3 ITGA2B KDM6B GSK3A CEP68 CELSR3 CELSR2 TBCD TMEM63A	2.71e-06	198	134	9	6865_DN
Drug	AC1L1ERT	ACTA1 ACTA2 ACTB ACTC1 ACTG1 ITGA2B	3.28e-06	69	134	6	CID000002920
Drug	DFMO	ACTA1 ACTA2 ACTB ACTC1 ACTG1 GSK3A EIF4G2 AOC3	3.88e-06	155	134	8	CID000003009
Drug	Ro-1724	ACTA1 ACTA2 ACTB RAPGEF4 ACTC1 ACTG1 TECTA	4.02e-06	110	134	7	CID000005087
Drug	epsilon-ATP	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.14e-06	41	134	5	CID000162262
Drug	AC1L8FNU	ACTA1 ACTA2 ACTB ACTC1 ACTG1	5.92e-06	44	134	5	CID000425429
Drug	TCNB	CAPN2 ACTA1 ACTA2 ACTB ACTC1 ACTG1 RYR1	6.77e-06	119	134	7	CID000008330
Drug	NpCaM	ACTA1 ACTA2 ACTB ACTC1 ACTG1	9.16e-06	48	134	5	CID000122259
Drug	AC1Q6LQU	ACTA1 ACTA2 ACTB ACTC1 ACTG1	9.16e-06	48	134	5	CID000072380
Drug	formamide	PNKP ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.11e-05	85	134	6	CID000000713
Drug	NSC106399	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.24e-05	51	134	5	CID000002887
Drug	AC1L22RD	ACTA1 ACTA2 ACTB ACTC1 ACTG1 SDHA	1.64e-05	91	134	6	CID000065183
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	LUC7L3 NCAPH CEP68 CENPI RAD54B ASPM MED13 TMEM63A	1.73e-05	190	134	8	2619_DN
Drug	foscarnet	COL4A3 ACTA1 ACTA2 ACTB ACTC1 ACTG1 ITGA2B TLR10	1.73e-05	190	134	8	CID000003414
Drug	C18:1n-7	ACTA1 ACTA2 ACTB ACTC1 ACTG1 TLR10	1.75e-05	92	134	6	CID000122325
Drug	Rp-cAMPS	CACNA1C VIPR1 ACTA1 ACTA2 ACTB RAPGEF4 ACTC1 ACTG1	2.01e-05	194	134	8	CID006426631
Drug	CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A	ABCA2 TECTA TDRD1 GSK3A CCN4 DOK4 ZNF516 EIF4G2	2.08e-05	195	134	8	4558_UP
Drug	Phenindione [83-12-5]; Down 200; 18uM; PC3; HT_HG-U133A	ABCC3 SIPA1L3 CAPN2 MED1 ADAM12 CEP68 DIP2A TMEM63A	2.41e-05	199	134	8	7289_DN
Drug	Cloxacillin sodium salt [642-78-4]; Up 200; 8.8uM; MCF7; HT_HG-U133A	SIPA1L3 HUWE1 ZZEF1 ADAM12 GSK3A PTPRB DOK4 TMEM63A	2.41e-05	199	134	8	2289_UP
Drug	candesartan cilexetil	COL4A3 ICAM1 ACTA1 ACTA2 ACTB ACTC1 ACTG1	2.46e-05	145	134	7	CID000002540
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A	KDM5B ESS2 ASIC2 ICAM1 CAPN2 ADAM12 GSK3A MLXIPL	2.50e-05	200	134	8	3936_UP
Drug	Strophanthidin [66-28-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A	ABCA2 SAMHD1 HINFP DIP2A CELSR3 EIF4G2 GAREM1 TMEM63A	2.50e-05	200	134	8	7182_DN
Drug	Dasatinib	CACNA1C ABCC3 FLT3 ACTA2 ACTC1 CHI3L1 NCAPH SVEP1 NSDHL CENPI MKI67 ASPM	2.66e-05	478	134	12	ctd:D000069439
Drug	bistheonellide A	ACTB ACTC1 ACTG1	3.18e-05	11	134	3	CID006441172
Drug	Viroisin	ACTB ACTC1 ACTG1	3.18e-05	11	134	3	CID000119538
Drug	oryzalin	ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.50e-05	63	134	5	CID000029393
Drug	etheno-NAD	PADI4 ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.51e-05	104	134	6	CID005288160
Drug	epoxiconazole	CACNA1C ABCC3 LUC7L3 ANXA7 RAPGEF4 GPX4 NRXN1 EIF4G2 MKI67 HECTD1	3.52e-05	341	134	10	ctd:C109476
Drug	BFDGE	ACTB ACTC1 ACTG1	4.22e-05	12	134	3	CID000091511
Drug	5-IAF	ACTA1 ACTA2 ACTB ACTC1 ACTG1	4.39e-05	66	134	5	CID000123822
Drug	Gdrgdsp	COL4A3 ACTB ACTC1 ACTG1 ITGA2B TNXB	4.58e-05	109	134	6	CID000115346
Drug	caged ATP	ACTA1 ACTA2 ACTB ACTC1 ACTG1	5.83e-05	70	134	5	CID000123806
Drug	AC1MNW2N	ACTA1 ACTA2 ACTB ACTC1 ACTG1	5.83e-05	70	134	5	CID003359490
Drug	thalidomide	ACTA1 ACTA2 ACTB ACTC1 ACTG1 BIRC2 MLXIPL IFNL2	6.51e-05	229	134	8	CID000005426
Drug	kabiramide C	ACTB ACTC1 ACTG1	6.92e-05	14	134	3	CID005288658
Drug	Co-protoporphyrin IX	ACTA1 ACTA2 ACTB ACTC1 ACTG1 PAPPA	7.14e-05	118	134	6	CID000004972
Drug	Pb m	ICAM1 ACTA1 ACTA2 ACTB ACTC1 ACTG1	7.14e-05	118	134	6	CID006327255
Drug	L-Carnosine	ACTA1 ACTA2 ACTB ACTC1 ACTG1	7.14e-05	73	134	5	CID000009369
Drug	C3H2N2O3S	ACTA1 ACTA2 ACTB ACTC1 ACTG1	7.62e-05	74	134	5	CID000448652
Drug	AC1LD8HW	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.13e-05	75	134	5	CID000644061
Drug	AC1L1KC5	CACNA1C ACTA1 ACTA2 ACTB RAPGEF4 ACTC1 ACTG1 BIRC2 GSK3A RYR1 UBXN11 DNAJC10	8.73e-05	541	134	12	CID000005428
Drug	AC1L9EF8	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.04e-04	79	134	5	CID000443315
Drug	2C5P	ACTA1 ACTA2 ACTB ACTC1 ACTG1 CELSR3	1.07e-04	127	134	6	CID000447961
Drug	6-trans-leukotriene B4	ABCC3 ICAM1 ACTA1 ACTA2 ACTB ACTC1 ACTG1 RYR1	1.10e-04	247	134	8	CID000000169
Drug	Corticosterone [50-22-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	VIPR1 SIPA1L3 KDM6B ZZEF1 SVEP1 ASB1 EPB41L2	1.11e-04	184	134	7	3244_UP
Drug	NSC613009	ACTA1 ACTA2 ACTB ACTC1 ACTG1 RYR1	1.22e-04	130	134	6	CID000003800
Drug	Thioguanosine [85-31-4]; Down 200; 12.6uM; MCF7; HT_HG-U133A	NCAPH CEP68 CENPI RAD54B MKI67 ASPM MED13	1.23e-04	187	134	7	4989_DN
Drug	plakin	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.24e-04	82	134	5	CID000018752
Drug	Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A	FLT3 CAPN2 ZZEF1 RYR1 PTPRB DOK4 TMEM63A	1.36e-04	190	134	7	4144_UP
Drug	Dicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A	ABCA2 SIPA1L3 ICAM1 CAPN2 ETS2 KDM6B EIF4G2	1.36e-04	190	134	7	1483_UP
Drug	Latex	NCAPH SVEP1 CENPI MKI67 ASPM PAPPA TNXB	1.40e-04	191	134	7	ctd:D007840
Drug	Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; PC3; HT_HG-U133A	ABCC3 CYP20A1 KDM6B ADAM12 GSK3A TSR1 CENPI	1.49e-04	193	134	7	3667_DN
Drug	5152487; Up 200; 10uM; MCF7; HT_HG-U133A_EA	VIPR1 GSK3A CEP68 MELTF CELSR3 DOK4 CAPN5	1.49e-04	193	134	7	896_UP
Drug	Hydrastinine hydrochloride [4884-68-8]; Up 200; 16.4uM; MCF7; HT_HG-U133A	ABCC3 ICAM1 HUWE1 GSK3A RYR1 CCN4 DOK4	1.49e-04	193	134	7	2283_UP
Drug	D-myo-inositol 1,4-bisphosphate	ACTA1 ACTA2 ACTB ACTC1 ACTG1	1.56e-04	86	134	5	CID000000805
Drug	NSC3260	ANXA7 ACTA1 ACTA2 ACTB ACTC1 ACTG1 RYR1	1.59e-04	195	134	7	CID000220461
Drug	Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A	PADI4 FLT3 ICAM1 ITGA2B TECTA GSK3A RYR1	1.59e-04	195	134	7	2225_UP
Drug	Paroxetine maleate [64006-44-6]; Down 200; 1uM; PC3; HT_HG-U133A	ABCC3 NEU3 SVEP1 GSK3A PTPRB EIF4G2 TMEM63A	1.59e-04	195	134	7	3821_DN
Drug	Graveoline [485-61-0]; Down 200; 14.4uM; PC3; HT_HG-U133A	ABCC3 CELSR3 DOK4 ZNF516 EIF4G2 SLC35F6 TMEM63A	1.64e-04	196	134	7	3716_DN
Drug	Fluvoxamine maleate [61718-82-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	ABCA2 SIPA1L3 TDRD1 CELSR2 RAD54B MKI67 TMEM63A	1.64e-04	196	134	7	7333_DN
Drug	Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A	VIPR1 CAPN2 CUL9 GSK3A ZNF516 CAPN5 TMEM63A	1.64e-04	196	134	7	7213_UP
Drug	beta- Belladonnine dichloroethylate [191355-47-2]; Down 200; 6uM; PC3; HT_HG-U133A	ICAM1 ADAM12 DOK4 RAD54B SENP2 ASB1 WDR62	1.64e-04	196	134	7	6638_DN
Drug	Cetirizine dihydrochloride [83881-52-1]; Down 200; 8.6uM; MCF7; HT_HG-U133A	MED20 SIPA1L3 MED1 KDM6B TDRD1 CEP68 ASB1	1.64e-04	196	134	7	2829_DN
Drug	Sulfaguanidine [57-67-0]; Down 200; 18.6uM; HL60; HG-U133A	SFMBT1 ESS2 GSK3A CEP68 DIP2A EPB41L2 TBCD	1.64e-04	196	134	7	1995_DN
Drug	CGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A	VIPR1 ABCC3 ASIC2 HUWE1 RAD54B AOC3 ASB1	1.70e-04	197	134	7	6412_DN
Drug	Fosfosal [6064-83-1]; Down 200; 18.4uM; MCF7; HT_HG-U133A	ACTA2 CUL9 DOK4 ASB1 CAPN5 TBCD TMEM63A	1.70e-04	197	134	7	4823_DN
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; MCF7; HT_HG-U133A	COL4A3 ESS2 NEU3 ITGA2B GSK3A DOK4 TMEM63A	1.70e-04	197	134	7	2291_UP
Drug	Piperacillin sodium salt [59703-84-3]; Down 200; 7.4uM; MCF7; HT_HG-U133A	SIPA1L3 ICAM1 GSK3A USP19 RGL1 DOK4 WDR62	1.70e-04	197	134	7	3939_DN
Drug	Harmaline hydrochloride dihydrate [6027-98-1]; Down 200; 14uM; PC3; HT_HG-U133A	ABCC3 ABCA2 ESS2 ICAM1 ACTA2 ASB1 CAPN5	1.70e-04	197	134	7	6623_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	ACTA2 CUL9 MED1 KDM6B TDRD1 USP19 WDR62	1.70e-04	197	134	7	1496_DN
Drug	PHA-00846566E [724718-26-7]; Up 200; 10uM; PC3; HT_HG-U133A	MED20 ADAM12 USP19 CELSR3 DOK4 CENPI CAPN5	1.70e-04	197	134	7	7046_UP
Drug	Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; PC3; HT_HG-U133A	KDM5B ACTA1 RAPGEF4 ITGA2B CEP68 PAPPA TBCD	1.70e-04	197	134	7	6759_UP
Drug	Myosmine [532-12-7]; Down 200; 27.4uM; PC3; HT_HG-U133A	ABCC3 ABCA2 ICAM1 ITGA2B SVEP1 GSK3A TMEM63A	1.75e-04	198	134	7	4293_DN
Drug	Caffeic acid [3331-39-5]; Down 200; 22.2uM; HL60; HT_HG-U133A	MED20 PADI4 CELSR3 CELSR2 RAD54B SLC35F6 TMEM63A	1.75e-04	198	134	7	3053_DN
Drug	Bergenin monohydrate [477-90-7]; Up 200; 11.6uM; MCF7; HT_HG-U133A	VIPR1 ZZEF1 RYR1 RGL1 ZNF516 CAPN5 TMEM63A	1.75e-04	198	134	7	7224_UP
Drug	estradiol, USP; Up 200; 0.01uM; HL60; HT_HG-U133A	ICAM1 CAPN2 ACTA1 GSK3A MLXIPL PAPPA TBCD	1.75e-04	198	134	7	2701_UP
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A	SIPA1L3 ETS2 TDRD1 CEP68 DOK4 WDR62 TMEM63A	1.75e-04	198	134	7	6930_UP
Drug	pioglitazone HCl; Down 200; 10uM; MCF7; HT_HG-U133A	VIPR1 ICAM1 ETS2 TDRD1 DOK4 SENP2 ASB1	1.75e-04	198	134	7	7506_DN
Drug	5'IATR	ACTB ACTC1 ACTG1	1.80e-04	19	134	3	CID000074997
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.19e-11	8	129	5	DOID:13099 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.19e-11	8	129	5	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.19e-11	8	129	5	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTA2 ACTB ACTC1 ACTG1	8.19e-11	8	129	5	DOID:14004 (implicated_via_orthology)
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.66e-10	10	129	5	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTA2 ACTB ACTC1 ACTG1	3.66e-10	10	129	5	DOID:13832 (implicated_via_orthology)
Disease	Severe Congenital Microcephaly	PNKP STAMBP WDR62 TBCD	1.00e-05	31	129	4	C3853041
Disease	Microcephaly	PNKP NCAPH STAMBP WDR62 TBCD	1.15e-05	67	129	5	C0025958
Disease	Microlissencephaly	PNKP STAMBP WDR62 TBCD	1.29e-05	33	129	4	C1956147
Disease	Baraitser-Winter syndrome	ACTB ACTG1	1.90e-05	2	129	2	cv:C1853623
Disease	Moyamoya disease 1	ACTA2 RNF213	1.90e-05	2	129	2	C2931384
Disease	Iris Coloboma with Ptosis, Hypertelorism, and Mental Retardation	ACTB ACTG1	1.90e-05	2	129	2	C1855722
Disease	Fryns-Aftimos Syndrome	ACTB ACTG1	1.90e-05	2	129	2	C1853623
Disease	primary autosomal recessive microcephaly (is_implicated_in)	NCAPH ASPM WDR62	4.38e-05	16	129	3	DOID:0070296 (is_implicated_in)
Disease	Moyamoya Disease	ACTA2 RNF213 SAMHD1	5.31e-05	17	129	3	C0026654
Disease	non-Hodgkin lymphoma (is_marker_for)	ANXA7 ICAM1	5.67e-05	3	129	2	DOID:0060060 (is_marker_for)
Disease	lung non-small cell carcinoma (is_marker_for)	ICAM1 BIRC2 CHI3L1 NCAPH PTPRB MKI67	1.03e-04	169	129	6	DOID:3908 (is_marker_for)
Disease	Gingival bleeding	ASIC2 NRXN1	1.13e-04	4	129	2	HP_0000225
Disease	Moyamoya disease (is_implicated_in)	ACTA2 RNF213	1.88e-04	5	129	2	DOID:13099 (is_implicated_in)
Disease	Child Development Disorders, Specific	PNKP STAMBP TBCD	2.74e-04	29	129	3	C0085997
Disease	Child Development Deviations	PNKP STAMBP TBCD	2.74e-04	29	129	3	C0085996
Disease	Congenital myopathy with fiber type disproportion	ACTA1 RYR1	2.81e-04	6	129	2	cv:C0546264
Disease	primary pulmonary hypertension (is_implicated_in)	RYR1 SMAD9	2.81e-04	6	129	2	DOID:14557 (is_implicated_in)
Disease	Developmental Disabilities	PNKP STAMBP TBCD	3.04e-04	30	129	3	C0008073
Disease	Uveoretinal Coloboma	ACTB ACTG1	3.93e-04	7	129	2	C4554007
Disease	Liver carcinoma	VIPR1 ACTB MED1 NCAPH MLXIPL CELSR3 MKI67 ASPM WDR62	4.03e-04	507	129	9	C2239176
Disease	nemaline myopathy (implicated_via_orthology)	ACTB ACTC1	5.22e-04	8	129	2	DOID:3191 (implicated_via_orthology)
Disease	diffuse large B-cell lymphoma (is_marker_for)	ICAM1 MKI67	5.22e-04	8	129	2	DOID:0050745 (is_marker_for)
Disease	Congenital ocular coloboma (disorder)	ACTB ACTG1	6.69e-04	9	129	2	C0009363
Disease	Malignant tumor of colon	KDM5B ICAM1 ACTA2 RAD54B MKI67	6.86e-04	159	129	5	C0007102
Disease	Kunitz-type protease inhibitor 2 measurement	SIPA1L3 RYR1	8.34e-04	10	129	2	EFO_0008200
Disease	Congenital neurologic anomalies	ACTB ACTG1	8.34e-04	10	129	2	C0497552
Disease	Cranioschisis	ACTB ACTG1	8.34e-04	10	129	2	C0265541
Disease	hypertrophic cardiomyopathy (biomarker_via_orthology)	ICAM1 CAPN2	8.34e-04	10	129	2	DOID:11984 (biomarker_via_orthology)
Disease	WNT1-inducible-signaling pathway protein 1 measurement	CCN4 FYB2	8.34e-04	10	129	2	EFO_0008321
Disease	glioblastoma (is_marker_for)	CHI3L1 PTPRB ASPM	9.48e-04	44	129	3	DOID:3068 (is_marker_for)
Disease	Copper-Overload Cirrhosis	ACTA2 MKI67	1.02e-03	11	129	2	C1876165
Disease	visual epilepsy (is_implicated_in)	TBC1D24 ASPM	1.02e-03	11	129	2	DOID:11832 (is_implicated_in)
Disease	uveitis (implicated_via_orthology)	ICAM1 AOC3	1.02e-03	11	129	2	DOID:13141 (implicated_via_orthology)
Disease	granulins measurement	ITGA2B CELSR2	1.22e-03	12	129	2	EFO_0008141
Disease	Cardiomyopathy, Dilated	ACTA1 ACTC1 SDHA	1.22e-03	48	129	3	C0007193
Disease	acute myeloid leukemia (is_marker_for)	ABCC3 FLT3 CHI3L1	1.30e-03	49	129	3	DOID:9119 (is_marker_for)
Disease	Autosomal Dominant Myotubular Myopathy	ACTA1 RYR1	1.43e-03	13	129	2	C3661489
Disease	Centronuclear myopathy	ACTA1 RYR1	1.43e-03	13	129	2	C0175709
Disease	X-linked centronuclear myopathy	ACTA1 RYR1	1.43e-03	13	129	2	C0410203
Disease	Myopathy, Centronuclear, 1	ACTA1 RYR1	1.43e-03	13	129	2	C4551952
Disease	Congenital Structural Myopathy	ACTA1 RYR1	1.43e-03	13	129	2	C0752282
Disease	Malformations of Cortical Development	WDR62 TBCD	1.67e-03	14	129	2	C1955869
Disease	Myopathy, Centronuclear, Autosomal Dominant	ACTA1 RYR1	1.67e-03	14	129	2	C1834558
Disease	Tubular Aggregate Myopathy	ACTA1 RYR1	1.67e-03	14	129	2	C0410207
Disease	Cortical Dysplasia	WDR62 TBCD	1.67e-03	14	129	2	C0431380
Disease	Schizophrenia	CACNA1C ESS2 ICAM1 ACTB CHI3L1 ADAM12 GSK3A NRXN1 PLA2G4B TNXB SDHA	1.75e-03	883	129	11	C0036341
Disease	Autosomal recessive primary microcephaly	ASPM WDR62	1.92e-03	15	129	2	cv:C3711387
Disease	response to statin, LDL cholesterol change measurement	CELSR2 EPB41L2	1.92e-03	15	129	2	EFO_0007804, GO_0036273
Disease	Autosomal Recessive Centronuclear Myopathy	ACTA1 RYR1	1.92e-03	15	129	2	C3645536
Disease	Hypertrophic Cardiomyopathy	CACNA1C ACTA1 ACTC1	2.01e-03	57	129	3	C0007194
Disease	MHPG measurement, 5-HIAA measurement	COL4A3 ADAM12	2.47e-03	17	129	2	EFO_0005132, EFO_0005133
Disease	Congenital Fiber Type Disproportion	ACTA1 RYR1	2.77e-03	18	129	2	C0546264
Disease	Schizophrenia	CHI3L1 NRXN1	2.77e-03	18	129	2	cv:C0036341
Disease	type 2 diabetes mellitus (is_marker_for)	ICAM1 CHI3L1 AOC3 PAPPA	3.05e-03	136	129	4	DOID:9352 (is_marker_for)
Disease	hydrocephalus (implicated_via_orthology)	CELSR2 HYDIN	3.09e-03	19	129	2	DOID:10908 (implicated_via_orthology)
Disease	Profound Mental Retardation	KDM6B NRXN1 WDR62 TBCD	3.29e-03	139	129	4	C0020796
Disease	Mental Retardation, Psychosocial	KDM6B NRXN1 WDR62 TBCD	3.29e-03	139	129	4	C0025363
Disease	Mental deficiency	KDM6B NRXN1 WDR62 TBCD	3.29e-03	139	129	4	C0917816
Disease	ovarian cancer (is_marker_for)	ANXA7 ICAM1 CHI3L1	3.33e-03	68	129	3	DOID:2394 (is_marker_for)
Disease	Malaria	ICAM1 NCR3	3.42e-03	20	129	2	C0024530
Disease	kidney disease (biomarker_via_orthology)	ABCC3 MKI67	3.77e-03	21	129	2	DOID:557 (biomarker_via_orthology)
Disease	type 1 diabetes mellitus (is_marker_for)	ICAM1 CHI3L1 AOC3	3.91e-03	72	129	3	DOID:9744 (is_marker_for)
Disease	Hereditary hearing loss and deafness	COL4A3 ACTG1 TECTA SDHA	3.93e-03	146	129	4	cv:C0236038
Disease	Autosomal Recessive Primary Microcephaly	ASPM WDR62	4.14e-03	22	129	2	C3711387
Disease	Hepatitis, Chronic	ACTA2 MKI67	4.14e-03	22	129	2	C0019189
Disease	Chronic active hepatitis	ACTA2 MKI67	4.14e-03	22	129	2	C0520463
Disease	progranulin measurement	ITGA2B CELSR2	4.14e-03	22	129	2	EFO_0004625
Disease	Chronic Persistent Hepatitis	ACTA2 MKI67	4.14e-03	22	129	2	C0149519
Disease	Primary microcephaly	ASPM WDR62	4.14e-03	22	129	2	C0431350
Disease	Cryptogenic Chronic Hepatitis	ACTA2 MKI67	4.14e-03	22	129	2	C0524611

Protein segments in the cluster

Peptide	Gene	Start	Entry
STFLNLPFQGIRCQL	TDRD1	816	Q9BXT4
CSLFRSFRQALNDGP	EXOC3L4	81	Q17RC7
GPRTLANLAEFFCRD	CYP27C1	76	Q4G0S4
PEGQNPCFLRSFVRA	CEP68	551	Q76N32
QALASPGSCLEEFRA	COL4A3	1596	Q01955
RFDPTQFQDCIIQGL	BZW1	26	Q7L1Q6
FGARLLELCNQGLFE	BAG6	861	P46379
TIGNERFRCPETLFQ	ACTA1	251	P68133
CDQDAQSPGILRLQF	CDCP1	316	Q9H5V8
GNERFRCPEALFQPS	ACTB	251	P60709
GNERFRCPEALFQPS	ACTG1	251	P63261
QCFRLLLLAGANPDF	ASB1	206	Q9Y576
TIGNERFRCPETLFQ	ACTA2	251	P62736
CLFNLPEVRESFGGQ	ADAM12	411	O43184
LQCALNRPAFFAERL	ANXA7	411	P20073
GEFLLRVFTDVPSNC	CAPN5	481	O15484
SFQCPDGLGFSRQVL	CCN4	321	O95388
FLLGINQADLPFACT	CELSR2	2426	Q9HCU4
DLGFSVSQRCFVLQP	ASPM	86	Q8IZT6
SRLGCFPDNNSEDFV	CFAP91	376	Q7Z4T9
RDAFCVFEQNQGLPL	AOC3	426	Q16853
FPAVTLCNLNGFRFS	ASIC2	86	Q16515
VISPDDFSSGRCFQL	RAD54B	196	Q9Y620
ELLLDRYGNLTSPNC	RGL1	111	Q9NZL6
PALLQRNGSFANFLC	ABCC3	836	O15438
TLRDRLCSDGFLFPQ	ANKRD36C	11	Q5JPF3
EPLGLQCTFINDFFT	PADI4	621	Q9UM07
GDFLQCSFSILEDQP	DDI1	311	Q8WTU0
TLPLIQDFFRGCAAS	MIR1915HG	116	Q5T4H9
RSRQPLVLGDNCFAD	INKA1	181	Q96EL1
LLQTGLAEPERCNFT	PTPRB	16	P23467
DTLGAALCPTFRIDN	PTPRB	61	P23467
CLLNSFPGDLEFEQI	KIAA0825	16	Q8IV33
FLPCSFNASQGRLAI	NCR3	36	O14931
TGNCLDSFPAELFRP	LRRC47	161	Q8N1G4
AFSPVLLQFCTDPRN	KDM6B	1196	O15054
GSFCGQDLRFPLTNA	CHI3L1	361	P36222
QLRQDIASGRLPCSF	EPB41L2	316	O43491
RFVCDLQNLLGFTPE	ETS2	441	P15036
NESISLPFQCKGRFS	GAREM1	206	Q9H706
LDISLRPSNFRDCGQ	LRRC31	486	Q6UY01
RSQGLRIFCNAPDFI	KCTD4	151	Q8WVF5
GFCPAELFTNTRSDL	LUC7L3	41	O95232
PYNLFLSGDSLRCLQ	KDM5B	181	Q9UGL1
FACEQNLLSRPDGSA	EXOSC5	31	Q9NQT4
ELTGFRELFQTPCTD	MKI67	1831	P46013
LGFGPCAEEQAFLSR	PLA2G4B	256	P0C869
RLPDLISDALFCNGQ	NRXN1	1061	Q9ULB1
FDNFDPVTLSSCQRG	PAPPA	1181	Q13219
SIRLECVFLPDQGAF	TMEM63A	541	O94886
ESGTHFPLFLLCLQQ	EIF4G2	666	P78344
RGLQSFVQCQPFERL	HUWE1	616	Q7Z6Z7
TGQCLEFLEDSPFLQ	CRYGN	106	Q8WXF5
FPNLTSFLGCQLADA	FLT3	936	P36888
FLRDPFSQALSRCQL	ESS2	251	Q96DF8
EDLGLNFQFCPSSRI	HECTD1	2406	Q9ULT8
IGDFESNLFCQIPNL	HYDIN	3916	Q4G0P3
SFFDELRCLGTQLPN	GSK3A	401	P49840
LSQLDPSNCLGIRGF	KLHL17	186	Q6TDP4
ALLPFVNCRDAGQDR	CACNA1C	2176	Q13936
GTQEFSPLCLRALAF	EPOP	31	A6NHQ4
AGFVLSADRCVPLNN	FCGBP	1991	Q9Y6R7
PGCLEASVTFNLFRL	IFNL2	171	Q8IZJ0
QSLCPDGQRDEFGFL	ABCA2	71	Q9BZC7
AGFRQQLSLTLCPAN	C1orf53	31	Q5VUE5
LGETFDLQLGRFNCP	CAPRIN2	1026	Q6IMN6
PRSFTFLNDACQGLE	CUL9	2326	Q8IWT3
GANFSCRTELDLRPQ	ICAM1	181	P05362
LGFSGTQECPELRFA	CYP20A1	401	Q6UW02
GPCQNFAPEFELLAR	DNAJC10	701	Q8IXB1
CDAFLNVFQSRGLRP	DIP2A	646	Q14689
DCLNRSGSFPLEQLQ	CENPI	331	Q92674
LEPDLFNCTSPAFRE	CELSR3	2171	Q9NYQ7
AECGLRILAFPCNQF	GPX4	91	P36969
QADLGPCILDFQSRN	HINFP	106	Q9BQA5
RNECLEAGTLFQDPS	CAPN2	36	P17655
LSSLCRAGDPNFNIV	DNAH2	2101	Q9P225
LAAEGFGNRLCFLEP	RYR1	36	P21817
FGNRLCFLEPTSNAQ	RYR1	41	P21817
TDRFNVFLLPCPNLD	DOK4	136	Q8TEW6
RACSNPSFLRFQLDF	MFSD5	31	Q6N075
GLLQFEVCPLSESRF	MED1	436	Q15648
PISCFLRQGSAQELN	LRRC74B	71	Q6ZQY2
FALFENGPCLIADTN	MED20	76	Q9H944
FQCQGRFSTRSPLEL	GAREM2	231	Q75VX8
LPSFGFTLNSEGCNR	SENP2	146	Q9HC62
INGRLFACPREQFDS	RAPGEF4	736	Q8WZA2
AFCDDAVGLRFNPVL	RAP1GAP2	226	Q684P5
LLCPNGARAEVSQFA	MELTF	601	P08582
LNIAFNFLTDLPGCS	TLR10	471	Q9BXR5
ALLPCLDESRFENLG	SAMHD1	76	Q9Y3Z3
TRAGLPCQDLEFVQF	SDHA	281	P31040
SNFFRCPEDLSLLNI	PLAC8L1	6	A1L4L8
ACSNNSRNGIFDLPI	FYB2	671	Q5VWT5
AQLLCSRPDDGFPFN	SEMA4B	306	Q9NPR2
NDLLLSCPHFRNEIG	SIPA1L3	421	O60292
PQVRFFLGDLCSRQD	NSDHL	76	Q15738
FSCADRLFALNLGLP	PNKP	306	Q96T60
LLQDQCTNLFSPFGA	MED13	1191	Q9UHV7
AEGGQCPSLLFDLRD	ITGA2B	91	P08514
GFFLRGNSTTLCQPD	SVEP1	2411	Q4LDE5
EPGGRQLLDLNCFLS	MLXIPL	236	Q9NP71
FTDPSNNRNRFCLGL	SMAD9	301	O15198
NCPFLENSLETLRFS	BIRC2	246	Q13490
TIGNERFRCPETLFQ	ACTC1	251	P68032
EDRQICPSLAGFQFT	NCAPH	311	Q15003
EGFQRLALSRQLCEP	NEU3	261	Q9UQ49
RCGIINDPSNSSFLE	TECTA	911	O75443
CNDPGRRLIDQSFLA	TBC1D24	161	Q9ULP9
LRIDNTCAPISFDLG	TMEM268	46	Q5VZI3
ASLFCNPSFIGDTLR	RNF213	2231	Q63HN8
LPATENLNADFRFCV	TAS2R7	146	Q9NYW3
LQAAPRCFFGIRSEA	TIGD3	216	Q6B0B8
QFFLQCLNLRPSAAG	ZNF516	381	Q92618
CPLIFKLFSSIQGRN	VIPR1	86	P32241
GHFTLDQCLNLFTRP	USP19	1056	O94966
ECFRQGTPLIAFSLL	TSR1	571	Q2NL82
PSLDTFLERCRQFGV	RLF	331	Q13129
LGPIDALNFFCEQLR	WDR97	1481	A6NE52
GRLCPQFLQLASANT	STAMBP	261	O95630
IFLNGNRERPLNVFC	TNXB	4046	P22105
DFLNPNGSDCTLVLF	TXNDC15	201	Q96J42
RPLTDIDFCSGAQLQ	TMEM102	21	Q8N9M5
NLFTSFPGDSLLCGR	PRSS42P	61	Q7Z5A4
NPRGTLEDALDAFCQ	SLC35F6	241	Q8N357
FEDQRACLPSGSFLT	WDR62	416	O43379
LLDFAQSEPAQNFCG	ZZEF1	1291	O43149
LIAPGSRLECQAFQD	SFMBT1	161	Q9UHJ3
CLIPFDFSRLDGNLL	TBCD	161	Q9BTW9
LFGGLQCPNLTESRA	THSD7B	211	Q9C0I4
TLSSLQQCNPRDGFD	TOM1L2	371	Q6ZVM7
NLLDNDPSFFCRFTV	NAE1	111	Q13564
FSLEQPRCVFDGLAS	UPK3B	106	Q9BT76
PAGNSFLEDCELSRQ	UPRT	91	Q96BW1
STQRCLRDILDGFFP	UBXN11	256	Q5T124
NEFSPLNILEPFCLA	LDAH	221	Q9H6V9