Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 CRYBG2 RIN3 LAMA5 ADGRL1 ATG2A REV3L LARS2 BIRC6 PLEKHG5 RNF43 MDN1 COQ4 NLRC5 CACNA1H GPC2 CABIN1 PRDM16 TOP3A RASAL1	6.50e-09	1105	131	20	35748872
Pubmed	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	GRM6 PIAS2 PIAS1	1.04e-06	6	131	3	16144832
Pubmed	Signaling via PINCH: Functions, binding partners and implications in human diseases.	LIMS2 LIMS1	1.41e-05	2	131	2	27590440
Pubmed	Multi-omics integration identifies cell-state-specific repression by PBRM1-PIAS1 cooperation.	PIAS1 PBRM1	1.41e-05	2	131	2	38190100
Pubmed	A Cav3.2/Stac1 molecular complex controls T-type channel expression at the plasma membrane.	STAC CACNA1H	1.41e-05	2	131	2	27149520
Pubmed	Long noncoding RNA FER1L4 regulates rheumatoid arthritis via targeting NLRC5.	FER1L4 NLRC5	1.41e-05	2	131	2	31694750
Pubmed	Requirement for PINCH in skeletal myoblast differentiation.	LIMS2 LIMS1	1.41e-05	2	131	2	36385586
Pubmed	Regulation of Cytochrome P450 2B10 (CYP2B10) Expression in Liver by Peroxisome Proliferator-activated Receptor-β/δ Modulation of SP1 Promoter Occupancy.	CYP2B6 PPARD	1.41e-05	2	131	2	27765815
Pubmed	Focal adhesion proteins Pinch1 and Pinch2 regulate bone homeostasis in mice.	LIMS2 LIMS1	1.41e-05	2	131	2	31723057
Pubmed	LIM domain proteins Pinch1/2 regulate chondrogenesis and bone mass in mice.	LIMS2 LIMS1	1.41e-05	2	131	2	33083097
Pubmed	The investigation of relevancy between PIAS1 and PIAS2 gene expression and disease severity of multiple sclerosis.	PIAS2 PIAS1	1.41e-05	2	131	2	31084243
Pubmed	Expression of PIAS Genes in Migraine Patients.	PIAS2 PIAS1	1.41e-05	2	131	2	33763841
Pubmed	XTP8 stimulates migration and invasion of gastric carcinoma through interacting with TGIF1.	TGIF1 DEPDC1B	1.41e-05	2	131	2	32196592
Pubmed	Role of PINCH and its partner tumor suppressor Rsu-1 in regulating liver size and tumorigenesis.	LIMS2 LIMS1	1.41e-05	2	131	2	24058607
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	GCM2 BACH2 PPARD BIRC6 PIAS1 RNF43 LIMS2 TGIF1 PBRM1 GTF3C1 PRDM16 TOP3A	1.64e-05	709	131	12	22988430
Pubmed	PIAS genes as disease markers in bipolar disorder.	PIAS2 PIAS1	4.21e-05	3	131	2	30861611
Pubmed	Brief research report: Effects of Pinch deficiency on cartilage homeostasis in adult mice.	LIMS2 LIMS1	4.21e-05	3	131	2	36743414
Pubmed	Consequences of loss of PINCH2 expression in mice.	LIMS2 LIMS1	4.21e-05	3	131	2	16317048
Pubmed	PIAS proteins modulate transcription factors by functioning as SUMO-1 ligases.	PIAS2 PIAS1	4.21e-05	3	131	2	12077349
Pubmed	Characterization of PINCH-2, a new focal adhesion protein that regulates the PINCH-1-ILK interaction, cell spreading, and migration.	LIMS2 LIMS1	4.21e-05	3	131	2	12167643
Pubmed	Immunohistochemical expression of Notch1, Jagged1, NF-κB and MMP-9 in colorectal cancer patients and the relationship to clinicopathological parameters.	JAG1 MMP9	4.21e-05	3	131	2	26406415
Pubmed	Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development.	PTPRU PTPRM	8.41e-05	4	131	2	9510027
Pubmed	A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading.	LIMS2 LIMS1	8.41e-05	4	131	2	11331308
Pubmed	Distinct effects of PIAS proteins on androgen-mediated gene activation in prostate cancer cells.	PIAS2 PIAS1	8.41e-05	4	131	2	11439351
Pubmed	The transactivating function of peroxisome proliferator-activated receptor gamma is negatively regulated by SUMO conjugation in the amino-terminal domain.	PIAS2 PIAS1	8.41e-05	4	131	2	15507114
Pubmed	AP1-dependent repression of TGFα-mediated MMP9 upregulation by PPARδ agonists in keratinocytes.	PPARD MMP9	8.41e-05	4	131	2	21496113
Pubmed	FLI-1 functionally interacts with PIASxalpha, a member of the PIAS E3 SUMO ligase family.	PIAS2 PIAS1	8.41e-05	4	131	2	16148010
Pubmed	Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification.	PIAS2 PIAS1	8.41e-05	4	131	2	15123625
Pubmed	Protein inhibitors of activated STAT resemble scaffold attachment factors and function as interacting nuclear receptor coregulators.	PIAS2 PIAS1	8.41e-05	4	131	2	11877418
Pubmed	ACE I/D, ACTN3 R577X, PPARD T294C and PPARGC1A Gly482Ser polymorphisms and physical fitness in Taiwanese late adolescent girls.	ACTN3 PPARD	8.41e-05	4	131	2	22247001
Pubmed	SUMO-1 modification of centrosomal protein hNinein promotes hNinein nuclear localization.	PIAS2 PIAS1	1.40e-04	5	131	2	16154161
Pubmed	Mechanism of blood-retinal barrier breakdown induced by HIV-1 (Review).	TJP2 MMP9	1.40e-04	5	131	2	24660027
Pubmed	Dissecting integrin-dependent regulation of neural stem cell proliferation in the adult brain.	LIMS2 LIMS1	1.40e-04	5	131	2	24719101
Pubmed	PIAS proteins are involved in the SUMO-1 modification, intracellular translocation and transcriptional repressive activity of RET finger protein.	PIAS2 PIAS1	1.40e-04	5	131	2	15907835
Pubmed	PAPILLARY THYROID CANCER IS CHARACTERIZED BY ALTERED EXPRESSION OF GENES INVOLVED IN THE SUMOYLATION PROCESS.	PIAS2 PIAS1	1.40e-04	5	131	2	26403403
Pubmed	PIAS1 and PIASxalpha function as SUMO-E3 ligases toward androgen receptor and repress androgen receptor-dependent transcription.	PIAS2 PIAS1	1.40e-04	5	131	2	12177000
Pubmed	Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.	PIAS2 PIAS1	1.40e-04	5	131	2	23202365
Pubmed	Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier.	PIAS2 PIAS1	1.40e-04	5	131	2	18579533
Pubmed	SUMO-triggered ubiquitination of NR4A1 controls macrophage cell death.	PIAS2 PIAS1	1.40e-04	5	131	2	28622293
Pubmed	Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation.	PIAS2 PIAS1	1.40e-04	5	131	2	15229330
Pubmed	T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B.	ANK2 CACNA1H	1.40e-04	5	131	2	29720258
Pubmed	SUMOylation of claudin-2.	PIAS2 TJP2	1.40e-04	5	131	2	22731716
Pubmed	SUMO Modification Reverses Inhibitory Effects of Smad Nuclear Interacting Protein-1 in TGF-β Responses.	PIAS2 PIAS1	1.40e-04	5	131	2	27703003
Pubmed	PINCH2 is a new five LIM domain protein, homologous to PINCHand localized to focal adhesions.	LIMS2 LIMS1	2.09e-04	6	131	2	12651156
Pubmed	Sumoylation modulates transcriptional activity of MITF in a promoter-specific manner.	PIAS2 PIAS1	2.09e-04	6	131	2	16029420
Pubmed	The SUMO E3-ligase PIAS1 regulates the tumor suppressor PML and its oncogenic counterpart PML-RARA.	PIAS2 PIAS1	2.09e-04	6	131	2	22406621
Pubmed	Repression of the Transactivating Capacity of the Oncoprotein PLAG1 by SUMOylation.	PIAS2 PIAS1	2.09e-04	6	131	2	15208321
Pubmed	Members of the PIAS family act as SUMO ligases for c-Jun and p53 and repress p53 activity.	PIAS2 PIAS1	2.09e-04	6	131	2	11867732
Pubmed	Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokines.	PIAS2 PIAS1	2.09e-04	6	131	2	18832723
Pubmed	Genomic organization of mouse and human 65 kDa FK506-binding protein genes and evolution of the FKBP multigene family.	FKBP10 FKBP9	2.09e-04	6	131	2	12036304
Pubmed	Identification of an elaborate complex mediating postsynaptic inhibition.	GPHN ARHGAP32	2.09e-04	6	131	2	27609886
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	GCM2 BACH2 PPARD CREB3L4 PIAS2 PIAS1 LIMS2 TGIF1 LIMS1 PBRM1 PRDM16	2.52e-04	808	131	11	20412781
Pubmed	ZNF451 is a novel PML body- and SUMO-associated transcriptional coregulator.	PIAS2 PIAS1	2.92e-04	7	131	2	18656483
Pubmed	An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity.	PIAS2 PIAS1	2.92e-04	7	131	2	17283066
Pubmed	RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation.	PIAS2 PIAS1	2.92e-04	7	131	2	22162396
Pubmed	Association of the nucleocapsid protein of the Seoul and Hantaan hantaviruses with small ubiquitin-like modifier-1-related molecules.	PIAS2 PIAS1	2.92e-04	7	131	2	14609633
Pubmed	Breaking down the barrier: the effects of HIV-1 on the blood-brain barrier.	TJP2 MMP9	2.92e-04	7	131	2	21641584
Pubmed	Inhibition of Stat1-mediated gene activation by PIAS1.	PIAS2 PIAS1	2.92e-04	7	131	2	9724754
Pubmed	Phospho-regulated SUMO interaction modules connect the SUMO system to CK2 signaling.	PIAS2 PIAS1	2.92e-04	7	131	2	19217413
Pubmed	Identification and characterization of CDS2, a mammalian homolog of the Drosophila CDP-diacylglycerol synthase gene.	CDS1 JAG1	2.92e-04	7	131	2	9889000
Pubmed	Transmembrane homodimerization of receptor-like protein tyrosine phosphatases.	PTPRU PTPRM	2.92e-04	7	131	2	15978577
Pubmed	DSSylation, a novel protein modification targets proteins induced by oxidative stress, and facilitates their degradation in cells.	PIAS1 MDN1 RPF2	3.13e-04	35	131	3	24515614
Pubmed	Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.	PHB2 PIAS2 PIAS1 HAL PRDM16	3.22e-04	156	131	5	37108203
Pubmed	Identification of rare DNA variants in mitochondrial disorders with improved array-based sequencing.	ACADS APEX2 TOP3A	3.69e-04	37	131	3	20843780
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	ELP5 REV3L DICER1 HEPH LIMS2 KANK1 MAPK15 MDN1 GTF3C1 SLC22A8 APEX2 SLC34A1 COQ4 VPS35L	3.84e-04	1293	131	14	15342556
Pubmed	Associations of polymorphisms of eight muscle- or metabolism-related genes with performance in Mount Olympus marathon runners.	ACTN3 PPARD	3.88e-04	8	131	2	20044476
Pubmed	SUMO E3 ligase activity of TRIM proteins.	PIAS2 PIAS1	3.88e-04	8	131	2	20972456
Pubmed	HIV-1 gp120 and drugs of abuse: interactions in the central nervous system.	TJP2 MMP9	3.88e-04	8	131	2	22591361
Pubmed	Sumoylation of Mdm2 by protein inhibitor of activated STAT (PIAS) and RanBP2 enzymes.	PIAS2 PIAS1	3.88e-04	8	131	2	12393906
Pubmed	SUMO-1 modification of the C-terminal KVEKVD of Axin is required for JNK activation but has no effect on Wnt signaling.	PIAS2 PIAS1	3.88e-04	8	131	2	12223491
Pubmed	ARIP3 (androgen receptor-interacting protein 3) and other PIAS (protein inhibitor of activated STAT) proteins differ in their ability to modulate steroid receptor-dependent transcriptional activation.	PIAS2 PIAS1	3.88e-04	8	131	2	11117529
Pubmed	Mutations in the paxillin-binding site of integrin-linked kinase (ILK) destabilize the pseudokinase domain and cause embryonic lethality in mice.	LIMS2 LIMS1	3.88e-04	8	131	2	23658024
Pubmed	Modification of de novo DNA methyltransferase 3a (Dnmt3a) by SUMO-1 modulates its interaction with histone deacetylases (HDACs) and its capacity to repress transcription.	PIAS2 PIAS1	3.88e-04	8	131	2	14752048
Pubmed	Interaction of protein inhibitor of activated STAT (PIAS) proteins with the TATA-binding protein, TBP.	PIAS2 PIAS1	3.88e-04	8	131	2	16522640
Pubmed	Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development.	LAMA5 OSBPL2	3.88e-04	8	131	2	21048919
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	RBBP5 PBRM1 VRTN CABIN1 MBD2	4.39e-04	167	131	5	20362541
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ARHGAP32 LAMA5 BIRC6 PBRM1 MDN1 CABIN1 DCAF4	4.70e-04	363	131	7	14691545
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	PIAS2 PIAS1 LIMS1 MDN1 EXD2 RPF2	4.92e-04	262	131	6	36880596
Pubmed	The interaction of Piasy with Trim32, an E3-ubiquitin ligase mutated in limb-girdle muscular dystrophy type 2H, promotes Piasy degradation and regulates UVB-induced keratinocyte apoptosis through NFkappaB.	PIAS2 PIAS1	4.98e-04	9	131	2	16816390
Pubmed	Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.	PIAS2 PIAS1	4.98e-04	9	131	2	21931855
Pubmed	Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of Alport syndrome.	LAMA5 MMP9	4.98e-04	9	131	2	10880400
Pubmed	An acetylation switch regulates SUMO-dependent protein interaction networks.	PIAS2 PIAS1	4.98e-04	9	131	2	22578841
Pubmed	A crosstalk between hSiah2 and Pias E3-ligases modulates Pias-dependent activation.	PIAS2 PIAS1	4.98e-04	9	131	2	17533377
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	VWA5B2 CRYBG2 ANK2 SLC7A14 PXDN PTPRM TJP2	5.35e-04	371	131	7	15747579
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	ARHGAP32 PSMB8 LAMA5 APEX2 FER1L4 TRIM56 RPF2 MMP9	6.06e-04	496	131	8	31343991
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	ARHGAP32 SH2D3A ARHGEF16 TJP2	6.14e-04	102	131	4	15778465
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	FRMPD4 RUSC2 MDN1 CABIN1	6.61e-04	104	131	4	9205841
Pubmed	DGKι regulates presynaptic release during mGluR-dependent LTD.	GPHN DGKI	7.57e-04	11	131	2	21119615
Pubmed	Genome-wide association study of metabolic traits reveals novel gene-metabolite-disease links.	ACADS PYROXD2	7.57e-04	11	131	2	24586186
Pubmed	Sumoylation of FOXP2 Regulates Motor Function and Vocal Communication Through Purkinje Cell Development.	PIAS2 PIAS1	7.57e-04	11	131	2	27009683
Pubmed	HSP70-Hrd1 axis precludes the oncorepressor potential of N-terminal misfolded Blimp-1s in lymphoma cells.	PIAS2 PIAS1	7.57e-04	11	131	2	28842558
Pubmed	The DNA sequence and comparative analysis of human chromosome 20.	LAMA5 BPIFB1 GATA5 ZNF831 AAR2 OSBPL2 JAG1 MMP9	7.93e-04	517	131	8	11780052
Pubmed	Alpha9 and beta8 integrin expression correlates with the merger of the developing mouse eyelids.	LAMA5 ITGB8	9.07e-04	12	131	2	10090148
Pubmed	Hypoxia-induced Slug SUMOylation enhances lung cancer metastasis.	PIAS2 PIAS1	9.07e-04	12	131	2	30612578
Pubmed	A role for Saccharomyces cerevisiae Centrin (Cdc31) in mitochondrial function and biogenesis.	DDI1 MDN1	9.07e-04	12	131	2	30251372
Pubmed	A cochlear progenitor pool influences patterning of the mammalian sensory epithelium via MYBL2.	JAG1 PRDM16	9.07e-04	12	131	2	39254648
Pubmed	Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.	PTPRU PTPRM	9.07e-04	12	131	2	9624153
Pubmed	Interplay of BAF and MLL4 promotes cell type-specific enhancer activation.	PBRM1 PRDM16	9.07e-04	12	131	2	33712604
Pubmed	SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling.	PIAS2 PIAS1	9.07e-04	12	131	2	34267330
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FRMPD4 ADGRL1 CSMD3 RUSC2 KANK1 PXDN CACNA1H	9.20e-04	407	131	7	12693553
Cytoband	Ensembl 112 genes in cytogenetic band chr1p36	CD164L2 CRYBG2 ZNF683 FAM43B ARHGEF16 PLEKHG5 DISP3 MST1L PRDM16	1.57e-04	681	131	9	chr1p36
GeneFamily	LIM zinc finger domain containing\|LIM domain containing	LIMS2 LIMS1	1.30e-04	4	85	2	1163
GeneFamily	Zinc fingers GRF-type\|Topoisomerases	APEX2 TOP3A	4.52e-04	7	85	2	135
GeneFamily	Zinc fingers MIZ-type	PIAS2 PIAS1	4.52e-04	7	85	2	85
Coexpression	GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_DN	GPHN FKBP10 RIN3 EPS8L1 KANK1 PTPRM EXD2 MMP9	7.47e-06	199	131	8	M8044
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HGABA	KIF21B FRMPD4 ANK2 BACH2 LAMA5 ADGRL1 REV3L FAM43B CSMD3 PIAS2 NT5DC3 ADCY1 DICER1 SLC7A14 RUSC2 FRY MDN1 GPC2	1.03e-05	1106	131	18	M39071
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FKBP10 DEPP1 LAMA5 AK7 KANK1 MAPK15 BNIPL	1.20e-06	183	131	7	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CRYBG2 GCM2 ACTN3 CSMD3 AK7 LIMS2 ITIH6	1.71e-06	193	131	7	315840bc48899f3a36d57b19197509de19716e3d
ToppCell	10x3'2.3-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KIF21B RIN3 ZNF683 RUSC2 FRY SLC34A1 HAL	1.77e-06	194	131	7	5da8873cddff582e5693b32fd3aaebc102f65fc0
ToppCell	Fibroblasts-Pericytes\|Fibroblasts / lung cells shred on cell class, cell subclass, sample id	LAMA5 LIMS2 FRY APOLD1 JAG1 CACNA1H PRDM16	1.83e-06	195	131	7	c2ebc0b33bda9b35b9ef26d69e5d2c6acfdb6ff1
ToppCell	facs-Marrow-T_cells-18m-Lymphocytic-Klrb1a/b/c(-)_NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B IFITM10 RNF43 TRIM56 JAG1 MMP9	9.51e-06	165	131	6	eeb58d4db64ad37dc6b441eab22b05c24862e1a9
ToppCell	Ciliated_cells-A-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	VWA5B2 CD164L2 BPIFB1 HOATZ EPS8L1 MAPK15	9.51e-06	165	131	6	0ebdbbdb151fb797335013d5838af1c7bbc45b06
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell\|E16.5-samps / Age Group, Lineage, Cell class and subclass	CD164L2 ARHGEF16 RNF43 FCGBP CMAHP PRDM16	1.13e-05	170	131	6	5a64e05c263df915085988d881808221e2c0f2e2
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HMGCR PIAS1 CEP72 SLC35E4 DEPDC1B RASAL1	1.61e-05	181	131	6	3fe648db1cb8326066d8bde3ca1287c5c9af19bd
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBG2 DEPP1 BPIFB1 LARS2 FCGBP SLC38A8	1.76e-05	184	131	6	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CRYBG2 DEPP1 BPIFB1 LARS2 FCGBP SLC38A8	1.76e-05	184	131	6	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 PTPRM APOLD1 PRDM16	1.82e-05	185	131	6	c3105978d971da7d0fad1a717ee29afee5ed6357
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 PTPRM APOLD1 PRDM16	1.82e-05	185	131	6	4cfef50aeed5b3000ce5e864a41c13740b8267b1
ToppCell	facs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 PTPRM APOLD1 PRDM16	1.82e-05	185	131	6	09256c6f42f59b7eb89160b2ea706172a5b743be
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	FRMPD4 CSMD3 ADCY1 LIMS1 DGKI PRDM16	1.93e-05	187	131	6	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	facs-Heart-LV-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 LIMS2 PTPRM APOLD1 TJP2 PRDM16	1.99e-05	188	131	6	ed11e26ff4ef3d6314b5f5734062519b9aa285c1
ToppCell	facs-Heart-LV-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 LIMS2 PTPRM APOLD1 TJP2 PRDM16	1.99e-05	188	131	6	e5a8ca4613ab0bf1584b9e78959adf41d0bf379f
ToppCell	facs-Heart-LV-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 LIMS2 PTPRM APOLD1 TJP2 PRDM16	1.99e-05	188	131	6	0fc3a6562e6895f6fe7a93397eae842a75c60c93
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 CYP2B6 EPS8L1 ITGB8 TRIM56 TJP2	2.11e-05	190	131	6	6ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 FRY PTPRM APOLD1	2.18e-05	191	131	6	a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCell	facs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 FRY PTPRM APOLD1	2.18e-05	191	131	6	827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	LAMA5 LIMS2 FRY JAG1 CACNA1H PRDM16	2.18e-05	191	131	6	2da83c493e60ad0278848957645277d76737a188
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 LAMA5 LIMS2 FRY PTPRM APOLD1	2.31e-05	193	131	6	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 LAMA5 LIMS2 FRY PTPRM APOLD1	2.31e-05	193	131	6	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	droplet-Fat-Mat-18m-Endothelial-Cd36+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 LAMA5 LIMS2 KANK1 PTPRM APOLD1	2.38e-05	194	131	6	74d0eaa76f6d9af14110dfe5b4bf9751b99ff6e3
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 BPIFB1 EPS8L1 ITGB8 FCGBP RASAL1	2.45e-05	195	131	6	fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DEPP1 ADCY1 LIMS2 PTPRM JAG1 DGKI	2.45e-05	195	131	6	a432d69b0172211ee4d53675936a1dc9ce1ae1f0
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 LIMS2 FRY APOLD1 JAG1 CACNA1H	2.52e-05	196	131	6	1d94cecd378a829dd8014fc086d7fca48c953a91
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164L2 LAMA5 ARHGEF16 FCGBP BNIPL TJP2	2.52e-05	196	131	6	9554ac6eb5f381bcde3ba40c32aa3fc340974540
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	LAMA5 LIMS2 FRY APOLD1 JAG1 CACNA1H	2.52e-05	196	131	6	aacec48285bcb7ccf1b538187071885e3602cc49
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VWA5B2 DEPP1 LIMS2 FRY PXDN APOLD1	2.59e-05	197	131	6	a312d9cf4ced949307eb9620be4eed926300b892
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	CRYBG2 MCIDAS HOATZ EPS8L1 AK7 MAPK15	2.67e-05	198	131	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	CRYBG2 MCIDAS HOATZ EPS8L1 AK7 MAPK15	2.67e-05	198	131	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	LPS_only-Epithelial_airway-airway_epithelial\|LPS_only / Treatment groups by lineage, cell group, cell type	CRYBG2 HOATZ EPS8L1 AK7 FCGBP MAPK15	2.67e-05	198	131	6	e035380578c01b0243bfef29ca9b50cc17cce771
ToppCell	LPS_only-Epithelial_airway\|LPS_only / Treatment groups by lineage, cell group, cell type	CRYBG2 HOATZ EPS8L1 AK7 FCGBP MAPK15	2.67e-05	198	131	6	ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCell	NS-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGAP32 CDS1 BPIFB1 HOATZ EPS8L1 ITGB8	2.74e-05	199	131	6	d64adb68502be596ce55fb2cb63fe1cfa2c5f8ba
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FKBP10 ANK2 FSTL3 ROR2 HEPH PXDN	2.74e-05	199	131	6	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGAP32 ROR2 BPIFB1 ITGB8 FCGBP RASAL1	2.82e-05	200	131	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / Treatment groups by lineage, cell group, cell type	FKBP9 EPS8L1 LIMS2 FRY PTPRM JAG1	2.82e-05	200	131	6	b17eb1587ca86c3d40515128a00a8d8fd787fccf
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CD164L2 ANK2 ACTN3 GRM6 FCGBP	4.15e-05	130	131	5	7d4319aae42acc914757796877b8f0d874acbec4
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ARHGAP32 CDS1 ZNF831 CACNA1H RASAL1	6.52e-05	143	131	5	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWA5B2 FAM43B GRM6 CREB3L4 DISP3	6.74e-05	144	131	5	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	kidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GPHN ANK2 GTF3C1 SLC22A8 SLC34A1	6.97e-05	145	131	5	47a3bb973a508d3097213a2d86ad1ce697af9bae
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	B3GNT4 MCIDAS HOATZ AK7 MAPK15	8.44e-05	151	131	5	e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	B3GNT4 MCIDAS HOATZ AK7 MAPK15	8.44e-05	151	131	5	633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCell	Leuk-UTI-Lymphocyte-T_NK-NK_CD56bright\|Leuk-UTI / Disease, Lineage and Cell Type	FKBP10 PYROXD2 RNF43 STAC DCAF4	1.01e-04	157	131	5	db0057741d06e212a9543cb4b011659b79efeafc
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP2B6 FRMPD4 LAMA5 GRM6 JAG1	1.04e-04	158	131	5	d78e7e52657dc094430291fec07e9c298be9e584
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RIN3 DEPP1 PSMB8 LIMS2 SLC22A8	1.14e-04	161	131	5	a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell-Endo\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RIN3 DEPP1 PSMB8 LIMS2 SLC22A8	1.17e-04	162	131	5	0bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Ctxn3_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ANKRD63 PTPRU ZNF831 PEAK1 RASAL1	1.17e-04	162	131	5	4d13c271b4f63cf32980e5643b5d5951165fe8b5
ToppCell	primary_visual_cortex-Non-neuronal-endothelial_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RIN3 DEPP1 PSMB8 LIMS2 SLC22A8	1.17e-04	162	131	5	5799a602ef8d83925907e8e34532428be7330228
ToppCell	COPD-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	RIN3 IFITM10 STAC FRY JAG1	1.32e-04	166	131	5	e2cad1db536d5ad5a34c337c19b5e7d1a2851552
ToppCell	Endothelial-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	ANK2 ZNF831 MAGED4 APOLD1 SLC35E4	1.32e-04	166	131	5	c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA5B2 ADCY1 SLC7A14 DISP3 CACNA1H	1.39e-04	168	131	5	4e1b522c7400c9d87f63c00e4e1dd07136095cd6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	BPIFB1 ZNF831 MAPK15 PXDN RASAL1	1.39e-04	168	131	5	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DDI1 RNF43 NLRC5 CMAHP RASAL1	1.39e-04	168	131	5	273168eefe0dae5494ac6ff5306bb307f06dc9c5
ToppCell	Control-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	RIN3 BACH2 IFITM10 FRY JAG1	1.39e-04	168	131	5	d7118d39253ed9790908b850088ebfc5a86f4065
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWA5B2 DEPP1 BPIFB1 ACTN3 SLC7A14	1.39e-04	168	131	5	17d46f993dc4ae22b8087808582aba77f5c61892
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CRYBG2 LARS2 LIMS2 TRMT10A DEPDC1B	1.47e-04	170	131	5	12aa9bdb18f3bf6da2a25984d08fe9497e5570ed
ToppCell	facs-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B BACH2 LARS2 CMAHP RASAL1	1.51e-04	171	131	5	a31c23406cf6d6a17358a8fb41d392a7fb0306e0
ToppCell	facs-Lung-nan-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B BACH2 LARS2 CMAHP RASAL1	1.51e-04	171	131	5	43d8fd9b9546e84a652564fe96b514b34b06262b
ToppCell	droplet-Fat-Mat-18m-Lymphocytic-lymphocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21B GRM6 RNF43 MDN1 NLRC5	1.55e-04	172	131	5	226de1a5d4a360d3ae01b0235fea19521ec623a0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L6_THEMIS_C6orf48\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8L1 PTPRU ITGB8 LIMS2 MAPK15	1.60e-04	173	131	5	8bc916ccf687df0341ec1d77d62844bf890cad47
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT4 HOATZ ARHGEF16 FCGBP MAPK15	1.60e-04	173	131	5	a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BPIFB1 CREB3L4 ADCY1 FCGBP RASAL1	1.60e-04	173	131	5	e4d9a9a781acc531bc81c3fcee24d637e805c8e1
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 DDI1 APOLD1 CACNA1H PRDM16	1.60e-04	173	131	5	a2c1ef3f4d7e9f68fc77ee7c42a4727bdea5da94
ToppCell	facs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT4 HOATZ AK7 MAPK15 CACNA1H	1.60e-04	173	131	5	27ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 DDI1 APOLD1 CACNA1H PRDM16	1.60e-04	173	131	5	4830136f1f1976e00ac9af9062a531ac42533041
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 DDI1 APOLD1 CACNA1H PRDM16	1.60e-04	173	131	5	0b79e2a4fd19d524c24b69a6b524ffc6affdabe5
ToppCell	droplet-Fat-SCAT-30m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT4 DEPP1 LIMS2 APOLD1 PRDM16	1.60e-04	173	131	5	eb58b0189e71e38d4f4f1cf544a82cde8d1c86bc
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	DEPP1 LIMS2 PTPRM JAG1 DGKI	1.60e-04	173	131	5	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	AT1_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CRYBG2 FSTL3 NT5DC3 LIMS2 YOD1	1.60e-04	173	131	5	b29816427428c7053017477f59b828bf1357f3b2
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT4 HOATZ AK7 MAPK15 CACNA1H	1.64e-04	174	131	5	f1510b0f7771936adf29ae3572feab55db31832b
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	B3GNT4 HOATZ AK7 MAPK15 CACNA1H	1.64e-04	174	131	5	5d5d2fc60afff47f997751e8e9ca1367a22d19ec
ToppCell	BAL-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	CRYBG2 LAMA5 PTPRU ADCY1 DEPDC1B	1.68e-04	175	131	5	daf014e15a354956e9149c83fd89d0af0d07eb00
ToppCell	facs-Aorta\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 PSMB8 PTPRU LIMS2 APOLD1	1.73e-04	176	131	5	0b3491451be02c18a16cdb875645be47eb867a7f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRU ITGB8 LIMS2 MAPK15 SLC38A8	1.73e-04	176	131	5	ed7ba2a3af3b060dec98b60f09f96000a67f7e63
ToppCell	facs-Aorta-Heart-24m-Endothelial-aortic_endothelial_cell\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 APOLD1 MBD2	1.82e-04	178	131	5	8017aaecd6275d8173c516f6f3a68ea991f3c1b0
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 ACTN3 GRM6 PLEKHG5 RNF43	1.82e-04	178	131	5	41745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCell	facs-Marrow-T-cells-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA5 ACTN3 GRM6 PLEKHG5 RNF43	1.82e-04	178	131	5	eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCell	facs-Aorta-Heart-24m-Endothelial\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIN3 DEPP1 LIMS2 APOLD1 MBD2	1.82e-04	178	131	5	46333db0d205580189062bf9df839c97196ad161
ToppCell	367C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DEPP1 ZNF683 ATG2A MINPP1 PLEKHG5	1.87e-04	179	131	5	5aa8465e943b6b666c7f8b1937fcc3764bfe91f6
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FKBP10 CDS1 ATXN7L2 ZNF683 PTPRM	1.87e-04	179	131	5	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	AT1-AT2_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ANK2 FSTL3 BACH2 PXDN CACNA1H	1.92e-04	180	131	5	3c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell	facs-Heart-RA-24m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DEPP1 IFITM10 LIMS2 KANK1 APOLD1	1.92e-04	180	131	5	174c643e046646e3b305dd7e5b120d2c9a46690f
ToppCell	368C-Endothelial_cells-Endothelial-E\|368C / Donor, Lineage, Cell class and subclass (all cells)	DEPP1 LAMA5 PLEKHG5 LIMS2 FRY	1.92e-04	180	131	5	8ab16a0b9053bffc07b569a4f9e71749f56dde7e
ToppCell	Ciliated_cells-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	CD164L2 BPIFB1 HOATZ EPS8L1 MAPK15	1.92e-04	180	131	5	d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCell	368C-Endothelial_cells-Endothelial-E-\|368C / Donor, Lineage, Cell class and subclass (all cells)	DEPP1 LAMA5 PLEKHG5 LIMS2 FRY	1.92e-04	180	131	5	394cd465b88429b70eebb2957480dffcbc51cfe7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRU ITGB8 LIMS1 MAPK15 SLC38A8	1.97e-04	181	131	5	13270b6ba6a9c8e5681c6f40000c643ce1d9344a
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTPRU ITGB8 LIMS1 MAPK15 SLC38A8	1.97e-04	181	131	5	3e3c903b522dced6bec5dc447cc3f8bf9a9749e3
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT4 DEPP1 LIMS2 PTPRM APOLD1	1.97e-04	181	131	5	2e15c46e8260bb04d8264478c19a707221996026
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DEPP1 LIMS2 FRY PTPRM JAG1	2.02e-04	182	131	5	0639011cdd1c437ea8b7230896a4e6e5d7244ac2
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Deuterosomal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CDS1 MCIDAS HOATZ AK7 MAPK15	2.02e-04	182	131	5	000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD164L2 CDS1 FRMPD4 HEPH PRDM16	2.02e-04	182	131	5	fe4fb213dc0ca482b0f94097fe1b0a51fc2690e2
ToppCell	3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FKBP10 ANK2 FSTL3 DEPP1 FAM43B	2.07e-04	183	131	5	2beb5414958d38a5341870d55229f3b1707e76bf
ToppCell	E17.5-Epithelial-airway_epithelial_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MCIDAS DEPP1 HOATZ AK7 MAPK15	2.07e-04	183	131	5	07cebb0e186e1bff14ac2a6bb6f8412d4aaa2350
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK2 IFITM10 ITGB8 FCGBP RASAL1	2.07e-04	183	131	5	83592c332b1e82673f993d37c7f480befdc3dcda
ToppCell	IPF-Lymphoid-ILC_B\|Lymphoid / Disease state, Lineage and Cell class	ARHGAP32 RIN3 IFITM10 FRY JAG1	2.07e-04	183	131	5	9b507547e6adf78e46e7f542cd9958224ec5826a
ToppCell	E17.5-Epithelial-airway_epithelial_cell-club_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MCIDAS DEPP1 HOATZ AK7 MAPK15	2.07e-04	183	131	5	e8e85e5be909f9cd85a6a041190bfcb855dfa1a4
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.4.4.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2B6 MCIDAS BPIFB1 EPS8L1 CREB3L4	2.13e-04	184	131	5	c2ca984551baf4becbefbe58bd1889828542b045
ToppCell	facs-Heart-LA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT4 BPIFB1 IFITM10 KANK1 SLC22A8	2.18e-04	185	131	5	1ecfca049c0c1110fd1b2256db7cb7abda6afb04
Drug	Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; MCF7; HT_HG-U133A	CRYBG2 RIN3 ACADS PPARD GRM6 RNF43 RUSC2 CACNA1H DCAF4	1.78e-06	197	128	9	6811_UP
Drug	rotenone; Up 200; 1uM; PC3; HT_HG-U133A	SLC17A2 FKBP10 CRYBG2 ACADS DEPP1 RUSC2 LIMS2 LINS1 APOLD1	1.93e-06	199	128	9	5920_UP
Disease	forced expiratory volume	SLC17A2 RIN3 GATA5 ACTN3 LARS2 PIAS1 ITGB8 PBRM1 SLC34A1 CEP72 VRTN CMAHP	1.60e-04	789	127	12	EFO_0004314
Disease	potassium voltage-gated channel subfamily F member 1 measurement	SLC17A2 SLC34A1	1.82e-04	5	127	2	EFO_0802890
Disease	response to placebo	STAC PXDN	1.82e-04	5	127	2	EFO_0008344
Disease	temporal arteritis (is_marker_for)	JAG1 MMP9	3.81e-04	7	127	2	DOID:13375 (is_marker_for)
Disease	brain measurement, neuroimaging measurement	VWA5B2 KIF21B RIN3 RBBP5 PBRM1 APOLD1 JAG1 DGKI PRDM16	6.45e-04	550	127	9	EFO_0004346, EFO_0004464
Disease	focal segmental glomerulosclerosis (biomarker_via_orthology)	PIAS1 MMP9	1.18e-03	12	127	2	DOID:1312 (biomarker_via_orthology)
Disease	hematologic cancer (implicated_via_orthology)	PIAS2 PIAS1	1.39e-03	13	127	2	DOID:2531 (implicated_via_orthology)
Disease	tetralogy of Fallot (is_implicated_in)	GATA5 JAG1	1.39e-03	13	127	2	DOID:6419 (is_implicated_in)
Disease	membranous glomerulonephritis (biomarker_via_orthology)	PTPRU MMP9	1.62e-03	14	127	2	DOID:10976 (biomarker_via_orthology)
Disease	ventricular septal defect (is_implicated_in)	GATA5 MMP9	1.62e-03	14	127	2	DOID:1657 (is_implicated_in)
Disease	atrial fibrillation (is_implicated_in)	ANK2 GATA5	1.62e-03	14	127	2	DOID:0060224 (is_implicated_in)
Disease	asthma, body mass index	ACTN3 ITGB8	1.62e-03	14	127	2	EFO_0004340, MONDO_0004979
Disease	Liver Cirrhosis, Experimental	SLC17A2 PSMB8 HMGCR FRY KANK1 PXDN SLC22A8 NLRC5 HAL MMP9	1.94e-03	774	127	10	C0023893
Disease	Tetralogy of Fallot	GATA5 JAG1	2.12e-03	16	127	2	C0039685
Disease	PROSTATE CANCER, HEREDITARY, 1	RNF43 ITGB8 MBD2	2.23e-03	60	127	3	C4722327
Disease	Malignant neoplasm of breast	CDS1 ADAT3 ANK2 DEPP1 SH2D3A GRM6 TRMT10A PBRM1 JAG1 NLRC5 GPC2 MMP9	2.36e-03	1074	127	12	C0006142
Disease	Abnormality of refraction	ARHGAP32 PRSS56 IFITM10 BIRC6 FRY EXD2 FER1L4 TJP2 PEAK1	2.59e-03	673	127	9	HP_0000539
Disease	smoking cessation	CYP2B6 CSMD3 BIRC6 EXD2 CACNA1H DEPDC1B	2.89e-03	325	127	6	EFO_0004319
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	RNF43 PBRM1	3.00e-03	19	127	2	DOID:4928 (is_marker_for)
Disease	Prostate cancer, familial	RNF43 ITGB8 MBD2	3.32e-03	69	127	3	C2931456
Disease	glaucoma (is_marker_for)	HEPH MMP9	3.32e-03	20	127	2	DOID:1686 (is_marker_for)
Disease	bipolar disorder, schizophrenia, response to lithium ion	ADCY1 CMAHP	3.32e-03	20	127	2	GO_0010226, MONDO_0004985, MONDO_0005090
Disease	advanced glycosylation end product-specific receptor ligand measurement	SLC17A2 SLC34A1	3.66e-03	21	127	2	EFO_0010762
Disease	skin neoplasm	BACH2 KANK1 HAL	4.04e-03	74	127	3	EFO_0004198
Disease	urinary metabolite measurement	ACADS PYROXD2 SLC22A8 HAL CABIN1	4.24e-03	245	127	5	EFO_0005116

Protein segments in the cluster

Peptide	Gene	Start	Entry
EMLLCLAGPASGPRS	ADAT3	91	Q96EY9
IDRPGMLCSFRIPGA	DCAF4	271	Q8WV16
TMGSPLRGPGLEALC	BACH2	406	Q9BYV9
CGKPAVRPLVDTGAM	DISP3	996	Q9P2K9
GPRPVVMLCGVEAIR	CYP2B6	71	P20813
MLELRHRGSCPGPRE	CDS1	1	Q92903
CNGGMRPVVRLPSLK	BIRC6	1236	Q9NR09
LPLLSAMREKPAGGI	BPIFB1	56	Q8TDL5
TCRLGERLQMDGAPP	CSMD3	2436	Q7Z407
CRIPKDSILGEPGMG	ACADS	246	P16219
NPPRLGEIFMLKRCG	ADAM21	396	Q9UKJ8
SSKPMGAPRGRLCEA	DEPP1	141	Q9NTK1
GMLVERPCPKGTRGI	ADGRL1	496	O94910
GLARLPEMKPRAGTE	AAR2	191	Q9Y312
ERRPACGGLPMLSFL	ARHGEF16	406	Q5VV41
KEMPPLCDGFGTRTL	DEPDC1B	341	Q8WUY9
LPAPGKCRKRRMPVG	CEP72	326	Q9P209
CVMRTVKKPGPNLGR	APEX2	476	Q9UBZ4
RASIVGPPMSCVRLA	DICER1	676	Q9UPY3
LGGPECCLRVSLMPL	ATG2A	1571	Q2TAZ0
TMGPRVKRAGPLDCR	ATXN7L2	616	Q5T6C5
MLKPKDLCPRAGTRT	ANKRD63	1	C9JTQ0
IVGSVGRCPPAMRLA	RASAL1	426	O95294
GMLSRPVCGIRGKTL	GPHN	126	Q9NQX3
MALLDVCGAPRGQRP	PSMB8	1	P28062
GGVLNPACAPEMRRL	YOD1	171	Q5VVQ6
MRGCRHNGLRIIIPP	ANK2	981	Q01484
TFPCLGKGMERPAAR	APOLD1	26	Q96LR9
LPEGELPLCSRMVSG	DDI1	361	Q8WTU0
LKAMRTPRCGVPDLG	MMP9	91	P14780
PGSGRRLCDLFMVKP	PBRM1	536	Q86U86
PIPGSQLPSGCRMRK	MDN1	4361	Q9NU22
DKMGVPICGACRRPI	LIMS2	191	Q7Z4I7
VGEDLCRGSVPALMP	LINS1	311	Q8NG48
EALRKMGLRPGVRHP	MAGED4	526	Q96JG8
LQRVPVAKMLCGPSG	MST1L	556	Q2TV78
RLIGCPLCRGVPSLM	GPC2	256	Q8N158
CILGEMLRGRPLFPG	MAPK15	206	Q8TD08
DGMTRGPVVRLPRAC	HMGCR	586	P04035
KLTLGPHGIRMQPCE	FAM43B	111	Q6ZT52
LPDMVRGARGPELCS	FER1L4	1611	A9Z1Z3
ALCGQRPMRKRLSAP	BNIPL	76	Q7Z465
MASPSGLCVLVRLPK	EXD2	126	Q9NVH0
RSLERKLPPSCMIGG	PEAK1	186	Q9H792
MEGCAVRRGSCPLLP	FAM218A	1	Q96MZ4
ERVAGRAGLKPPMLD	KIF21B	831	O75037
LVGLKMRTIACGPPQ	KANK1	771	Q14678
LGAPTRMAGVTPCIL	LAMA5	3501	O15230
RMAGVTPCILGPLEA	LAMA5	3506	O15230
SLRSRKLPDMGCSLP	ARHGAP32	1861	A7KAX9
RLPAGPRGMGTALKL	PHB2	11	Q99623
GDMLCPRGEVPTLRQ	PLCXD1	176	Q9NUJ7
LLPGCRVMATSRPGK	NLRC5	336	Q86WI3
RVMATSRPGKLPACL	NLRC5	341	Q86WI3
RMLALPGRALLCKPG	MCIDAS	21	D6RGH6
LTCGRDGEPEPMQKL	RBBP5	231	Q15291
GPPLISRTKCAEPMR	PTPRU	371	Q92729
VPCTRLPIRMAKALG	SLC34A1	491	Q06495
LGMCVGEKRIITIPP	FKBP9	211	O95302
ICPDGSRKPGMEGCR	ITGB8	406	P26012
PRATESGKRMDCPAL	MBD2	141	Q9UBB5
ACGLYMKLHGVPRPL	GATA5	266	Q9BWX5
RSLGLDRKMCPFGRA	ADCY1	1066	Q08828
MCPGERRKIIIPPFL	FKBP10	221	Q96AY3
SGVGKPLSPERCRML	HAL	196	P42357
SLCSLPCGPGERKKM	GRM6	516	O15303
PKVCGLPGARMTTDV	CABIN1	1676	Q9Y6J0
RSGLLPKGPAMLCRL	B3GNT4	16	Q9C0J1
GEPCRLAPAMIRISL	DGKI	681	O75912
LMSIPSPFRGRLCGL	FCGBP	4971	Q9Y6R7
PGKACRMLGGRPRCE	FSTL3	106	O95633
PRKVEMRRDPVLGFG	FRMPD4	76	Q14CM0
DPSVGSLKPMRLGCP	CRYBG2	1146	Q8N1P7
MREGKRGPPCILSFR	IFITM10	1	A6NMD0
RLCGLPGLQRPAAEM	COQ4	11	Q9Y3A0
IRLVTGPMGPCLRRH	ITIH6	1251	Q6UXX5
MEAPGPRALRTALCG	CD164L2	1	Q6UWJ8
GGPLGALRAMCKRTD	ELP5	101	Q8TE02
RTCVAAIPRLLPDGM	FRY	606	Q5TBA9
CKRPRMDPVLSGRSA	FAM90A20P	156	A6NIJ5
LGAIVRCDAVMPPGR	EPS8L1	101	Q8TE68
RNKMLQGPGRCPDRV	FAM240C	66	A0A1B0GVR7
KCSHIPGRRELRMPC	CACNA1H	301	O95180
LEGRGSLSPPLIMCT	CACNA1H	1066	O95180
VLPMGPNGKPERCLR	SLC22A8	61	Q8TCC7
MGGKPRPSGRIRSVL	CREB3L4	376	Q8TEY5
CRRALGPGLRPSTML	PRSS56	256	P0CW18
PGPALRTRTKCADPM	PTPRM	366	P28827
CPLGKMRLTIPCRAV	PIAS2	346	O75928
CPTAGLGPLREEAMK	RIN3	346	Q8TB24
RPCITMGSVIPDGAK	JAG1	861	P78504
RMLSCPVRLSEGPAA	RUSC2	516	Q8N2Y8
ILCGDRPGLMNVPRV	PPARD	356	Q03181
LRMALVPGKDCLTPV	LARS2	331	Q15031
RPLCTAPGTAPDMKR	NT5DC3	41	Q86UY8
LEPMPTFGKGLDLRR	PRDM16	1186	Q9HAZ2
PPMKIAGDCRAIRPT	GCM2	446	O75603
CSMAPPVDLLTGKVR	HEPH	366	Q9BQS7
GRKESQEMCPPGLLV	HOATZ	11	Q6PI97
PRPCLSLASKARMAG	RNF43	116	Q68DV7
MARGSALPRRPLLCI	ROR2	1	Q01974
DKMGVPICGACRRPI	LIMS1	186	P48059
PLGKMRLTIPCRALT	PIAS1	336	O75925
LICAMGVEPIGPRVK	SLC38A8	391	A6NNN8
TGMEKTLPPTDCRLR	OSBPL2	391	Q9H1P3
GCRTPRIELEEMGPS	RPF2	206	Q9H7B2
ISGERLPRPDKGKMR	ACTN3	86	Q08043
PRGIIEKSCQGPRMS	AGPS	341	O00116
IVDCTRPNGGRLPMK	CMAHP	181	Q9Y471
RCELCLGIMGGKPRH	ATG4D	326	Q86TL0
GPCKILGPRLEKMVA	TXN2	91	Q99757
IRLGLPGKMDRPTAA	SLC7A14	546	Q8TBB6
QGPAPRRRLLETMKG	TGIF1	121	Q15583
ELLPLGPVDGRSCSM	PLEKHG5	801	O94827
GRPGPIGVLLMKSRA	TJP2	301	Q9UDY2
LPRLTCMIRGIGDPL	VPS35L	316	Q7Z3J2
MLRAPGCLLRTSVAP	MINPP1	1	Q9UNW1
PGACVPALELTRKML	REV3L	2921	O60673
PMLEEGAGSKVPRCL	PYROXD2	121	Q8N2H3
KPLMRALDEGAGPCD	SH2D3A	451	Q9BRG2
TDGLAPQRCMGKLPK	STAC	151	Q99469
GRAVPIKAMVTCLPL	SLC17A2	261	O00624
DLVPGSRLGPTLMCL	PXDN	1221	Q92626
KRGSLPPTMPLEFVC	TOP3A	721	Q13472
LSMGRRHKLCSPDPG	VWA5B2	1031	Q8N398
PMPGGTRCRVLLLSL	SLC35E4	101	Q6ICL7
PRLGEGCEPISKRQM	TRMT10A	31	Q8TBZ6
MTVPCPSLGSDGRKR	ZNF831	1601	Q5JPB2
GRAPMRCPLCRKISE	TRIM64C	46	A6NLI5
GRAPMRCPSCRKISE	TRIM64	46	A6NGJ6
GLGRSLGFLPKMPRL	GTF3C1	786	Q12789
PRNMLPLVCKGEGSL	VRTN	71	Q9H8Y1
LERGGMASPAKRVPL	ZNF683	286	Q8IZ20
AALACVLRPSRGVMP	nan	111	Q8NAQ8
MPGDKRSPRITGLCP	TRIM56	501	Q9BRZ2
VAPSMALRDGVCRIP	PRO3102	16	Q9H379
QSRGLMPIKICILGP	AK7	361	Q96M32