Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontranscription coactivator activity

BCL9L KMT2C NCOA6 DYRK1B SMARCC1 NCOA1 SMARCD2 CTBP2 TRIM24 CREBBP MAML3 PBXIP1

1.67e-083039312GO:0003713
GeneOntologyMolecularFunctiontranscription coregulator activity

BCL9L NCOR2 KMT2C NCOA6 DYRK1B SMARCC1 NCOA1 SMARCD2 CTBP2 TRIM24 CREBBP MAML3 PBXIP1

2.00e-065629313GO:0003712
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

MAGI2 BCL9L NCOR2 KMT2C NCOA6 DYRK1B SMARCC1 NCOA1 SMARCD2 CTBP2 RIMS2 TRIM24 CREBBP MAML3 PBXIP1 LGALS3 SOS1

2.26e-0511609317GO:0030674
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

NCOR2 NCOA6 NCOA1 CTBP2

1.25e-0455934GO:0042974
GeneOntologyMolecularFunctionmolecular adaptor activity

MAGI2 BCL9L NCOR2 KMT2C NCOA6 DYRK1B SMARCC1 NCOA1 SMARCD2 CTBP2 RIMS2 TRIM24 CREBBP MAML3 PBXIP1 LGALS3 SOS1

1.56e-0413569317GO:0060090
GeneOntologyMolecularFunctionchromatin binding

FLI1 NCOR2 NCOA6 PYGO2 SMARCC1 NCOA1 SMARCD2 CTBP2 RUNX2 TRIM24 PRDM15 CREBBP

1.61e-047399312GO:0003682
GeneOntologyMolecularFunctionnuclear retinoid X receptor binding

NCOR2 NCOA6 NCOA1

1.62e-0423933GO:0046965
GeneOntologyMolecularFunctionstructural constituent of presynaptic active zone

CTBP2 RIMS2

5.90e-048932GO:0098882
GeneOntologyMolecularFunctionstructural constituent of synapse

MAGI2 CTBP2 RIMS2

9.84e-0442933GO:0098918
GeneOntologyCellularComponentnuclear protein-containing complex

BCL9L BPTF NCOR2 KMT2C NCOA6 RANBP2 PYGO2 WDR33 CDK12 SCAF8 CAMSAP3 SMARCC1 NCOA1 SMARCD2 CREBBP ATF6B AQR LGALS3

2.30e-0513779118GO:0140513
GeneOntologyCellularComponenttranscription regulator complex

BCL9L NCOR2 NCOA6 PYGO2 NCOA1 CTBP2 RUNX2 CREBBP ATF6B PBXIP1

2.66e-045969110GO:0005667
GeneOntologyCellularComponentribbon synapse

OTOF CTBP2 RIMS2

3.61e-0432913GO:0097470
GeneOntologyCellularComponentbasolateral plasma membrane

OTOF CALHM1 SLCO2B1 LRRC7 ITGA3 SLC26A1 ABCC10

4.97e-04320917GO:0016323
GeneOntologyCellularComponentperinuclear region of cytoplasm

MAGI2 BPTF SYNRG RANBP2 TTBK1 CLINT1 ATXN10 GNAS ITGA3 DOCK6 TESK1 KLHL20

7.21e-049349112GO:0048471
GeneOntologyCellularComponentbasal plasma membrane

OTOF CALHM1 SLCO2B1 LRRC7 ITGA3 SLC26A1 ABCC10

9.01e-04354917GO:0009925
GeneOntologyCellularComponentkinetochore

NCAPD3 SMARCC1 SMARCD2 ZNF207 CREBBP

1.17e-03181915GO:0000776
GeneOntologyCellularComponentMLL3/4 complex

KMT2C NCOA6

1.20e-0312912GO:0044666
GeneOntologyCellularComponentbasal part of cell

OTOF CALHM1 SLCO2B1 LRRC7 ITGA3 SLC26A1 ABCC10

1.32e-03378917GO:0045178
GeneOntologyCellularComponentbeta-catenin-TCF complex

BCL9L PYGO2

1.42e-0313912GO:1990907
GeneOntologyCellularComponentcondensed chromosome, centromeric region

NCAPD3 SMARCC1 SMARCD2 ZNF207 CREBBP

1.56e-03193915GO:0000779
GeneOntologyCellularComponentbrahma complex

SMARCC1 SMARCD2

1.65e-0314912GO:0035060
DomainSSDP_DNA-bd

SSBP2 SSBP4

6.72e-053892IPR008116
PathwayREACTOME_RUNX1_REGULATES_TRANSCRIPTION_OF_GENES_INVOLVED_IN_DIFFERENTIATION_OF_MYELOID_CELLS

RUNX2 CREBBP LGALS3

4.79e-067743M27799
PathwayWP_KLEEFSTRA_SYNDROME

KMT2C NCOA6 SMARCC1 SMARCD2

1.50e-0529744M48076
PathwayWP_NOTCH_SIGNALING_WP268

NCOR2 CTBP2 CREBBP MAML3

8.86e-0545744M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NCOR2 CTBP2 CREBBP MAML3

9.66e-0546744MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NCOR2 CTBP2 CREBBP MAML3

1.05e-0447744M7946
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA6 NCOA1 CREBBP

1.07e-0418743M26942
PathwayPID_HES_HEY_PATHWAY

NCOR2 NCOA1 RUNX2 CREBBP

1.14e-0448744M288
PathwayPID_AR_TF_PATHWAY

SMARCC1 NCOA1 TRIM24 CREBBP

1.69e-0453744M151
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

NCOA6 NCOA1 PERM1 CREBBP

1.95e-0455744M27145
PathwayBIOCARTA_VDR_PATHWAY

SMARCC1 NCOA1 CREBBP

2.60e-0424743M13404
PathwayREACTOME_CYTOPROTECTION_BY_HMOX1

NCOR2 NCOA6 NCOA1 CREBBP

2.73e-0460744M41830
PathwayREACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION

NCOA6 NCOA1 CREBBP

3.71e-0427743M26943
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

MAGI2 KMT2C CREBBP MAML3

3.72e-0465744M39682
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

NCOR2 NCOA1

4.02e-046742MM15663
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NCOR2 CREBBP MAML3

4.14e-0428743M6177
PathwayPID_RETINOIC_ACID_PATHWAY

NCOR2 NCOA1 CREBBP

5.09e-0430743M207
PathwayPID_RAS_PATHWAY

LGALS3 SOS1 SYNGAP1

5.09e-0430743M269
PathwayBIOCARTA_RARRXR_PATHWAY

NCOR2 NCOA1

5.61e-047742M6907
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF462 FLI1 BCL9L BPTF NCOR2 KMT2C NCOA6 RANBP2 PYGO2 SOBP SMARCC1 NCOA1 SMARCD2 CTBP2 SSBP2 TRIM24 CREBBP

6.83e-17351931738297188
Pubmed

Human transcription factor protein interaction networks.

ZNF462 FLI1 BCL9L BPTF NCOR2 KMT2C NCOA6 PYGO2 ZSCAN21 WDR33 SOBP SCAF8 SMARCC1 NCOA1 SMARCD2 CTBP2 MRPL38 SSBP2 ATXN10 SSBP4 TRIM24 CREBBP

2.00e-111429932235140242
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

BCL9L NCOR2 KMT2C NCOA6 PYGO2 WDR33 CDK12 SCAF8 SMARCC1 ZNF207 TRIM24 CREBBP TOR1AIP1 MAML3

2.16e-11457931432344865
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

BCL9L NCOA6 PYGO2 ZSCAN21 WDR33 SMARCC1 NCOA1 SMARCD2 SSBP2 TRIM24 CREBBP

1.62e-10268931133640491
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

BPTF SYNRG NCOR2 NCOA6 NCAPD3 RANBP2 CDK12 SCAF8 SAMD4B GTSE1 RALGAPB CAMSAP3 KLC2 SMARCC1 ZYX SOS1

2.41e-10774931615302935
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

FLI1 BPTF NCOR2 KMT2C NCOA6 NCAPD3 RANBP2 WIPF1 ZSCAN21 SMARCC1 NCOA1 SMARCD2 ZNF207 CLINT1 RUNX2 TRIM24 CREBBP ZYX

7.09e-101103931834189442
Pubmed

Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.

NCOR2 SMARCC1 SMARCD2 CTBP2 TRIM24 CREBBP

1.11e-094093634585037
Pubmed

Tagging genes with cassette-exchange sites.

ZNF462 BPTF NCOR2 KMT2C CDK12 SCAF8 GTSE1 SMARCC1 CREBBP TOR1AIP1 AQR

1.70e-09335931115741177
Pubmed

T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.

NCOR2 NCOA6 NCOA1 TRIM24 CREBBP

1.84e-092093511877444
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SYNRG NCOA6 CARMIL2 SAMD4B GTSE1 RALGAPB DYRK1B CAMSAP3 KLC2 CLINT1 GNAS DOCK6 TESK1 ZYX AQR

9.26e-09861931536931259
Pubmed

Natural helix 9 mutants of PPARγ differently affect its transcriptional activity.

NCOR2 NCOA1 TRIM24 CREBBP

9.94e-091093430595551
Pubmed

Activating signal cointegrator 2 belongs to a novel steady-state complex that contains a subset of trithorax group proteins.

KMT2C NCOA6 NCOA1 CREBBP

4.70e-081493412482968
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

ZNF462 EVA1C BPTF NCOR2 KMT2C SOBP SCAF8 SAMD4B RALGAPB CAMSAP3 CTBP2 LRRC7 GNAS RBBP8NL DOCK6 PRDM15 CREBBP MAML3

7.25e-081489931828611215
Pubmed

Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.

BPTF NCOR2 NCOA6 CDK12 SMARCC1 TRIM24

9.93e-088393628794006
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

NCOR2 KMT2C DYRK1B CIZ1 SMARCC1 NCOA1 SMARCD2 CTBP2 TRIM24 CREBBP

1.20e-07398931035016035
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

COL4A6 NCOR2 PYGO2 GTSE1 KLC2 ZNF207 CC2D1B CTBP2 BLOC1S1 TUG1 GNAS RUNX2 RIMS2 PRDM15 TOR1AIP1 SYNGAP1

1.36e-071215931615146197
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF462 BPTF ZSCAN21 CIZ1 SMARCC1 NCOA1 SMARCD2 ZNF207 KLF17 RUNX2 TRIM24 ATF6B ZYX

2.45e-07808931320412781
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

BPTF NCOR2 NCOA6 RANBP2 ZSCAN21 WDR33 CDK12 GTSE1 CIZ1 SMARCC1 ZNF207 CLINT1 TRIM24 TOR1AIP1

2.47e-07954931436373674
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

BPTF SYNRG KMT2C NCOA6 WDR33 CDK12 CIZ1 SMARCC1 CLINT1 CREBBP ZYX

2.60e-07549931138280479
Pubmed

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

NCOR2 NCOA6 NCOA1 CREBBP

2.77e-072193419596656
Pubmed

An Oct4-centered protein interaction network in embryonic stem cells.

ZNF462 BPTF KMT2C CAMSAP3 SMARCC1 SMARCD2 CTBP2

3.47e-0716793720362541
Pubmed

Impaired peroxisome proliferator-activated receptor gamma function through mutation of a conserved salt bridge (R425C) in familial partial lipodystrophy.

NCOR2 NCOA1 CREBBP

3.68e-07693317312272
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

MAGI2 SYN3 SRGAP3 DYRK1B CAMSAP3 LRRC7 RIMS2 SOS1 SYNGAP1

4.07e-0734793917114649
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

ZNF462 ZNF469 TTBK1 CC2D1B MRPL38 MAML3

4.51e-0710793611347906
Pubmed

Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.

SMARCC1 NCOA1 CREBBP

6.43e-0779339590696
Pubmed

S 26948: a new specific peroxisome proliferator activated receptor gamma modulator with potent antidiabetes and antiatherogenic effects.

NCOR2 NCOA1 CREBBP

6.43e-07793317704298
Pubmed

Aberrant association of promyelocytic leukemia protein-retinoic acid receptor-alpha with coactivators contributes to its ability to regulate gene expression.

NCOR2 NCOA1 CREBBP

1.03e-06893317475621
Pubmed

Oct4 links multiple epigenetic pathways to the pluripotency network.

BPTF NCOR2 WDR33 SCAF8 SMARCC1 CTBP2 ATXN10

1.29e-0620393722083510
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

BCL9L KMT2C NCAPD3 RANBP2 CDK12 SCAF8 SAMD4B RALGAPB CAMSAP3 CIZ1 ZNF207 CTBP2 MRPL38 PBXIP1 AQR LGALS3

2.13e-061497931631527615
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

ZNF462 NCOR2 KMT2C SMARCC1 NCOA1 SMARCD2 TRIM24

2.20e-0622093735785414
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

ZNF462 NCAPD3 RANBP2 GTSE1 CLINT1 TRIM24 CREBBP

2.34e-0622293737071664
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

ZNF462 BPTF KMT2C RANBP2 WDR33 GTSE1

2.79e-0614693623892456
Pubmed

Corepressors selectively control the transcriptional activity of PPARgamma in adipocytes.

NCOR2 NCOA1 CREBBP

3.01e-061193315681609
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

SYNRG NCOR2 RANBP2 GTSE1 ZNF207 CLINT1 TRIM24 CREBBP ZYX

3.10e-0644493934795231
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

ZNF462 KMT2C ZSCAN21 SMARCC1 NCOA1 SMARCD2 ZNF207 KLF17 CREBBP MAML3 ZYX

3.13e-06709931122988430
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

NCOR2 WDR33 SOBP CIZ1 NCOA1 CREBBP

3.52e-0615293638360978
Pubmed

Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2.

NCOR2 NCOA6 CREBBP

4.00e-061293311158331
Pubmed

Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.

NCOA6 NCOA1 CREBBP

4.00e-061293312189208
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

BPTF NCOA6 SMARCC1 SMARCD2 CTBP2 CREBBP

4.24e-0615793630186101
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

ZNF462 BCL9L BPTF KMT2C RANBP2 SMARCC1 SMARCD2 ZNF207 AQR

4.83e-0646993927634302
Pubmed

The NCOA1-CBP-NF-κB transcriptional complex induces inflammation response and triggers endotoxin-induced myocardial dysfunction.

NCOA1 CREBBP

7.07e-06293235339471
Pubmed

Runx2 is expressed in human glioma cells and mediates the expression of galectin-3.

RUNX2 LGALS3

7.07e-06293218438928
Pubmed

The transcriptional activity of Pygopus is enhanced by its interaction with cAMP-response-element-binding protein (CREB)-binding protein.

PYGO2 CREBBP

7.07e-06293219555349
Pubmed

Runt-Related Transcription Factor 2 (Runx2) Is Responsible for Galectin-3 Overexpression in Human Thyroid Carcinoma.

RUNX2 LGALS3

7.07e-06293228390192
Pubmed

Runx2 regulates the expression of GNAS on SaOs-2 cells.

GNAS RUNX2

7.07e-06293216442859
Pubmed

A nuclear factor, ASC-2, as a cancer-amplified transcriptional coactivator essential for ligand-dependent transactivation by nuclear receptors in vivo.

NCOA6 NCOA1 CREBBP

8.23e-061593310567404
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOR2 NCOA6 NCAPD3 RNF123 SMARCC1 NCOA1 ITGA3 TRIM24 CREBBP MAML3

8.29e-06638931031182584
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

RANBP2 PYGO2 CDK12 SAMD4B GTSE1 CAMSAP3 KLC2 SMARCD2 ZYX

8.46e-0650393916964243
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NCAPD3 CDK12 SCAF8 SAMD4B RALGAPB CAMSAP3 SMARCC1 CC2D1B PBXIP1 AQR

9.74e-06650931038777146
Pubmed

Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.

NCOR2 RANBP2 GTSE1 CREBBP SOS1

1.20e-0511093537219487
Pubmed

Identification of a polymorphic, neuron-specific chromatin remodeling complex.

SRGAP3 SMARCC1 SMARCD2

1.22e-051793312368262
Pubmed

Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.

NCOR2 NCOA1 CREBBP

1.22e-051793319183483
Pubmed

Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.

NCOR2 CTBP2 TRIM24 CREBBP LGALS3

1.37e-0511393523403292
Pubmed

Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene.

NCOA6 NCOA1 CREBBP

1.74e-051993322982455
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

BPTF NCOR2 NCAPD3 RANBP2 GTSE1 SMARCC1 CTBP2 MRPL38 TRIM24 PRDM15 CREBBP

1.85e-05857931125609649
Pubmed

High-resolution photocatalytic mapping of SARS-CoV-2 spike interactions on the cell surface.

DMRT3 EFNB3 SCAF8 GTSE1 CAMSAP3 CREBBP LGALS3

1.93e-0530793737499664
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

CACNA1S NCOR2 NCOA6 ZNF469 GTSE1 CLINT1 SOS1 SYNGAP1

2.08e-0543093835044719
Pubmed

Coactivator ASC-2 mediates heat shock factor 1-mediated transactivation dependent on heat shock.

NCOA6 CREBBP

2.12e-05393214960326
Pubmed

Glucose-stimulated PGC-1α couples with CBP and Runx2 to mediate intervertebral disc degeneration through transactivation of ADAMTS4/5 in diet-induced obesity mice.

RUNX2 CREBBP

2.12e-05393236403758
Pubmed

GCN5L1 interacts with αTAT1 and RanBP2 to regulate hepatic α-tubulin acetylation and lysosome trafficking.

RANBP2 BLOC1S1

2.12e-05393230333138
Pubmed

Inhibition effect of cypermethrin mediated by co-regulators SRC-1 and SMRT in interleukin-6-induced androgen receptor activation.

NCOR2 NCOA1

2.12e-05393227239967
Pubmed

The Ewing's sarcoma fusion protein, EWS-FLI, binds Runx2 and blocks osteoblast differentiation.

FLI1 RUNX2

2.12e-05393220665663
Pubmed

A novel, evolutionarily conserved gene family with putative sequence-specific single-stranded DNA-binding activity.

SSBP2 SSBP4

2.12e-05393212079286
Pubmed

Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene.

NCOA1 CREBBP

2.12e-05393210848596
Pubmed

The homeodomain protein Arix promotes protein kinase A-dependent activation of the dopamine beta-hydroxylase promoter through multiple elements and interaction with the coactivator cAMP-response element-binding protein-binding protein.

CREBBP ATF6B

2.12e-05393210644760
Pubmed

Activating signal cointegrator-2 is an essential adaptor to recruit histone H3 lysine 4 methyltransferases MLL3 and MLL4 to the liver X receptors.

KMT2C NCOA6

2.12e-05393218372346
Pubmed

Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis.

KMT2C NCOA6

2.12e-05393221330447
Pubmed

Role of CBP/p300 and SRC-1 in transcriptional regulation of the pulmonary surfactant protein-A (SP-A) gene by thyroid transcription factor-1 (TTF-1).

NCOA1 CREBBP

2.12e-05393211713256
Pubmed

Lack of coactivator interaction can be a mechanism for dominant negative activity by mutant thyroid hormone receptors.

NCOR2 NCOA1

2.12e-0539329751500
Pubmed

Insulin-like growth factor-1 increases skeletal muscle dihydropyridine receptor alpha 1S transcriptional activity by acting on the cAMP-response element-binding protein element of the promoter region.

CACNA1S CREBBP

2.12e-05393212407098
Pubmed

Galectin-3 promotes lamellipodia formation in epithelial cells by interacting with complex N-glycans on alpha3beta1 integrin.

ITGA3 LGALS3

2.12e-05393219755493
Pubmed

Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.

NCOA1 CREBBP

2.12e-05393211574547
Pubmed

Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor.

BCL9L PYGO2

2.12e-05393220637214
Pubmed

Modulation of androgen receptor transactivation by the SWI3-related gene product (SRG3) in multiple ways.

SMARCC1 NCOA1

2.12e-05393215923603
Pubmed

RUNX1 and RUNX2 upregulate Galectin-3 expression in human pituitary tumors.

RUNX2 LGALS3

2.12e-05393219020999
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLI1 NCOR2 NCOA6 RNF123 UBXN11 CDK12 CTBP2 CREBBP ZYX

3.01e-0559193915231748
Pubmed

FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.

FLI1 SMARCC1 SMARCD2

3.15e-052393330962207
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

ZNF462 BPTF RANBP2 WDR33 CDK12 SMARCC1 ZNF207 SSBP2 DOCK6 PBXIP1 AQR SYNGAP1

3.18e-051082931238697112
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ZNF462 KMT2C NCOA6 CDK12 SRGAP3 RALGAPB

3.27e-0522593612168954
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

WDR33 SRGAP3 DYRK1B CAMSAP3 SMARCC1 ZNF207 CTBP2 DOCK6 TOR1AIP1 ZYX SOS1

3.40e-05916931132203420
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

ZNF462 FLI1 BPTF ZSCAN21 CIZ1 SMARCC1 SMARCD2 TRIM24 PRDM15

3.75e-0560893936089195
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SYNRG NCOR2 KMT2C NCOA6 CDK12 GTSE1 ITGA3 SLC45A1 SSBP4 DOCK6 TESK1 ABCC10

3.89e-051105931235748872
Pubmed

Steroid receptor coactivator-1 and its family members differentially regulate transactivation by the tumor suppressor protein p53.

NCOA1 CREBBP

4.23e-05493210551785
Pubmed

Two of four alternatively spliced isoforms of RUNX2 control osteocalcin gene expression in human osteoblast cells.

RUNX2 CREBBP

4.23e-05493218321663
Pubmed

Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

CACNA1S RIMS2

4.23e-05493214660679
Pubmed

MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.

KMT2C CREBBP

4.23e-05493228398509
Pubmed

A signature motif in transcriptional co-activators mediates binding to nuclear receptors.

NCOA1 CREBBP

4.23e-0549329192902
Pubmed

Steroid receptor coactivator-1 interacts with the p50 subunit and coactivates nuclear factor kappaB-mediated transactivations.

NCOA1 CREBBP

4.23e-0549329556555
Pubmed

Direct association between the CREB-binding protein (CBP) and nuclear receptor corepressor (N-CoR).

NCOR2 CREBBP

4.23e-05493217073437
Pubmed

Human immunodeficiency virus type 1 (HIV-1) accessory protein Vpr induces transcription of the HIV-1 and glucocorticoid-responsive promoters by binding directly to p300/CBP coactivators.

NCOA1 CREBBP

4.23e-05493212208951
Pubmed

The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.

NCOA1 CREBBP

4.23e-05493211463834
Pubmed

Crucial role of the H11-H12 loop in stabilizing the active conformation of the human mineralocorticoid receptor.

NCOA1 TRIM24

4.23e-05493210935545
Pubmed

Analysis of the steroid receptor coactivator 1 (SRC1)-CREB binding protein interaction interface and its importance for the function of SRC1.

NCOA1 CREBBP

4.23e-05493211113179
Pubmed

Mouse cathepsin F: cDNA cloning, genomic organization and chromosomal assignment of the gene.

ZP1 KLC2

4.23e-05493210876093
Pubmed

Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3.

SYNRG CLINT1

4.23e-05493212858162
Pubmed

The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes.

AGXT CREBBP

4.23e-05493212169688
Pubmed

The co-regulators SRC-1 and SMRT are involved in interleukin-6-induced androgen receptor activation.

NCOR2 NCOA1

4.23e-05493228396297
Pubmed

A peroxisome proliferator-activated receptor gamma ligand inhibits adipocyte differentiation.

NCOA1 CREBBP

4.23e-05493210339548
Pubmed

Modulation of M2 macrophage polarization by the crosstalk between Stat6 and Trim24.

TRIM24 CREBBP

4.23e-05493231554795
Pubmed

LncRNA TUG1 sponges miR-204-5p to promote osteoblast differentiation through upregulating Runx2 in aortic valve calcification.

TUG1 RUNX2

4.23e-05493229016735
InteractionSP7 interactions

FLI1 BCL9L NCOR2 KMT2C NCOA6 RNF123 PYGO2 ZSCAN21 WDR33 SCAF8 SMARCC1 NCOA1 SMARCD2 TRIM24 CREBBP

5.59e-123049015int:SP7
InteractionEGR2 interactions

ZNF462 FLI1 BCL9L NCOR2 KMT2C NCOA6 PYGO2 SMARCC1 NCOA1 SSBP2 TRIM24 CREBBP

1.46e-111719012int:EGR2
InteractionNUP35 interactions

BCL9L NCOR2 KMT2C NCOA6 RANBP2 PYGO2 WDR33 CDK12 SCAF8 SMARCC1 ZNF207 TRIM24 CREBBP MAML3 KLHL20

5.95e-104249015int:NUP35
InteractionCRX interactions

ZNF462 FLI1 BCL9L NCOR2 KMT2C PYGO2 SMARCC1 NCOA1 SMARCD2 TRIM24 CREBBP LGALS3

1.42e-092549012int:CRX
InteractionTBXT interactions

NCOR2 KMT2C NCOA6 ZSCAN21 SMARCC1 SMARCD2 SSBP2 TRIM24 CREBBP

2.42e-09116909int:TBXT
InteractionLHX1 interactions

NCOR2 KMT2C PYGO2 ZSCAN21 SMARCD2 SSBP2 SSBP4 TRIM24

1.94e-08103908int:LHX1
InteractionSOX7 interactions

NCOR2 KMT2C SMARCC1 NCOA1 SMARCD2 TRIM24 CREBBP

8.10e-0882907int:SOX7
InteractionPAX7 interactions

FLI1 NCOR2 KMT2C PYGO2 ZSCAN21 SMARCD2 SSBP4 CREBBP

8.32e-08124908int:PAX7
InteractionTLX1 interactions

ZNF462 NCOR2 KMT2C PYGO2 ZSCAN21 SMARCC1 SMARCD2 SSBP2 CREBBP

8.82e-08175909int:TLX1
InteractionTEAD1 interactions

ZNF462 BPTF NCOR2 KMT2C ZSCAN21 NCOA1 SMARCD2 SSBP2 CREBBP

9.27e-08176909int:TEAD1
InteractionHNF4A interactions

ZNF462 BPTF NCOR2 KMT2C NCOA6 SMARCC1 NCOA1 SMARCD2 TRIM24 CREBBP

4.16e-072759010int:HNF4A
InteractionGCM1 interactions

NCOR2 KMT2C ZSCAN21 SMARCC1 SMARCD2 CREBBP

5.87e-0768906int:GCM1
InteractionETV4 interactions

FLI1 NCOR2 PYGO2 SMARCD2 TRIM24 CREBBP

6.41e-0769906int:ETV4
InteractionERG interactions

FLI1 NCOR2 KMT2C NCOA6 PYGO2 SMARCC1 SMARCD2 TRIM24 CREBBP

6.87e-07223909int:ERG
InteractionLHX4 interactions

BCL9L NCOR2 KMT2C PYGO2 SMARCD2 SSBP2 SSBP4 TRIM24

7.82e-07166908int:LHX4
InteractionETS1 interactions

BPTF SMARCC1 NCOA1 SMARCD2 RUNX2 TRIM24 CREBBP

1.17e-06121907int:ETS1
InteractionAR interactions

ZNF462 BCL9L NCOR2 KMT2C NCOA6 PYGO2 ZSCAN21 WDR33 SMARCC1 NCOA1 SMARCD2 CTBP2 SSBP2 GNAS RUNX2 TRIM24 CREBBP

1.60e-069929017int:AR
InteractionLHX2 interactions

BCL9L NCOR2 KMT2C SMARCC1 SMARCD2 SSBP2 SSBP4 TRIM24

1.63e-06183908int:LHX2
InteractionLHX3 interactions

NCOR2 KMT2C PYGO2 SMARCD2 SSBP2 SSBP4 TRIM24 CREBBP

1.77e-06185908int:LHX3
InteractionPAX9 interactions

FLI1 BCL9L NCOR2 KMT2C NCOA6 PYGO2 SMARCD2

1.89e-06130907int:PAX9
InteractionMYOD1 interactions

BPTF NCOR2 KMT2C SMARCC1 NCOA1 SMARCD2 TRIM24 CREBBP

2.52e-06194908int:MYOD1
InteractionGSC interactions

ZNF462 FLI1 BCL9L NCOR2 KMT2C CREBBP

2.53e-0687906int:GSC
InteractionGATA2 interactions

NCOR2 KMT2C NCOA6 SMARCC1 SMARCD2 SSBP2 TRIM24 CREBBP

3.05e-06199908int:GATA2
InteractionFEV interactions

ZNF462 NCOR2 KMT2C NCOA6 ZSCAN21 SMARCD2 TRIM24 CREBBP

3.53e-06203908int:FEV
InteractionLHX8 interactions

PYGO2 SMARCD2 SSBP2 SSBP4 ATF6B

3.85e-0653905int:LHX8
InteractionSOX9 interactions

KMT2C NCOA6 SMARCC1 SMARCD2 RUNX2 CREBBP

4.78e-0697906int:SOX9
InteractionRBBP5 interactions

KMT2C NCOA6 RNF123 PYGO2 WDR33 KLC2 SMARCC1 SMARCD2 CREBBP

5.48e-06287909int:RBBP5
InteractionTLE3 interactions

BCL9L NCOR2 PYGO2 CDK12 SCAF8 NCOA1 ZNF207 CTBP2 SSBP4 CREBBP

6.89e-063769010int:TLE3
InteractionCEBPA interactions

FLI1 BPTF NCOR2 KMT2C NCOA6 NCAPD3 RANBP2 WIPF1 ZSCAN21 SMARCC1 NCOA1 SMARCD2 ZNF207 CLINT1 RUNX2 TRIM24 CREBBP ZYX

8.20e-0612459018int:CEBPA
InteractionPPARG interactions

NCOR2 KMT2C NCOA6 SELENOK SMARCC1 NCOA1 TRIM24 CREBBP LGALS3

9.42e-06307909int:PPARG
InteractionFOS interactions

NCOR2 KMT2C NCOA6 SMARCC1 NCOA1 SMARCD2 RUNX2 TRIM24 CREBBP

1.07e-05312909int:FOS
InteractionTBR1 interactions

BCL9L NCOR2 KMT2C RNF123 PYGO2 SMARCD2

1.15e-05113906int:TBR1
InteractionSMG7 interactions

NCOR2 NCOA6 SCAF8 SAMD4B NCOA1 TRIM24 CREBBP ZYX AQR

1.28e-05319909int:SMG7
InteractionYWHAH interactions

SYNRG NCOA6 CARMIL2 SAMD4B GTSE1 RALGAPB CAMSAP3 KLC2 NCOA1 CLINT1 RIMS2 DOCK6 TESK1 CREBBP AQR SYNGAP1

2.68e-0511029016int:YWHAH
InteractionSRF interactions

FLI1 BPTF NCOR2 NCOA6 NCOA1 CREBBP

3.74e-05139906int:SRF
InteractionPAX6 interactions

ZNF462 BPTF NCOR2 KMT2C NCOA6 SMARCC1 SMARCD2 TRIM24 CREBBP

3.77e-05366909int:PAX6
InteractionNCOA1 interactions

NCOA6 SMARCC1 NCOA1 RUNX2 TRIM24 CREBBP

4.92e-05146906int:NCOA1
InteractionNANOG interactions

ZNF462 BPTF NCOR2 KMT2C NCAPD3 RANBP2 WDR33 SAMD4B GTSE1 TRIM24

5.67e-054819010int:NANOG
InteractionFOXI1 interactions

NCOR2 KMT2C SMARCD2 TRIM24 CREBBP

5.75e-0592905int:FOXI1
InteractionPYGO2 interactions

BCL9L PYGO2 KLC2 CREBBP

6.23e-0548904int:PYGO2
InteractionBCL9L interactions

BCL9L PYGO2 SSBP2 SSBP4

6.23e-0548904int:BCL9L
InteractionSOX17 interactions

NCOR2 KMT2C NCOA6 SMARCD2 TRIM24

6.70e-0595905int:SOX17
InteractionNFIX interactions

BPTF NCOR2 KMT2C ZSCAN21 SMARCC1 SMARCD2 TRIM24

7.09e-05227907int:NFIX
InteractionCHN2 interactions

SRGAP3 GNAS SLC26A1 ZYX SYNGAP1

7.40e-0597905int:CHN2
InteractionTFCP2L1 interactions

ZNF462 BPTF CAMSAP3 SMARCC1 SMARCD2

8.16e-0599905int:TFCP2L1
InteractionWWTR1 interactions

BPTF SYNRG NCOA6 CDK12 SMARCC1 CLINT1 RUNX2 CREBBP ZYX

1.12e-04422909int:WWTR1
InteractionBCL3 interactions

RNF123 NCOA1 CTBP2 CREBBP

1.14e-0456904int:BCL3
InteractionTPRX2 interactions

NCOA6 SMARCC1 SMARCD2 CREBBP

1.14e-0456904int:TPRX2
InteractionLHX6 interactions

BCL9L ZSCAN21 SSBP2 SSBP4

1.31e-0458904int:LHX6
InteractionSMC5 interactions

BPTF NCOR2 NCOA6 RANBP2 ZSCAN21 WDR33 CDK12 GTSE1 CIZ1 SMARCC1 ZNF207 CLINT1 TRIM24 TOR1AIP1

1.34e-0410009014int:SMC5
InteractionPAX8 interactions

NCOR2 KMT2C PYGO2 SMARCD2 CREBBP

1.40e-04111905int:PAX8
InteractionTHRA interactions

NCOR2 NCOA6 NCOA1 TRIM24 CREBBP

1.40e-04111905int:THRA
InteractionHELZ interactions

NCOR2 SAMD4B CTBP2 TRIM24 CREBBP ZYX KLHL20

1.53e-04257907int:HELZ
InteractionNR6A1 interactions

NCOR2 NCOA1 CREBBP

1.63e-0424903int:NR6A1
InteractionTFAP2B interactions

SSBP4 CREBBP KLHL20

1.63e-0424903int:TFAP2B
InteractionSOX2 interactions

ZNF462 FLI1 BCL9L BPTF NCOR2 KMT2C NCOA6 RANBP2 PYGO2 CDK12 SAMD4B SMARCC1 SMARCD2 CTBP2 CLINT1 RUNX2 TRIM24

1.63e-0414229017int:SOX2
InteractionLPXN interactions

AGXT GNAS ZYX SOS1 SYNGAP1

1.66e-04115905int:LPXN
InteractionFLI1 interactions

FLI1 SMARCC1 SMARCD2 CTBP2

1.70e-0462904int:FLI1
InteractionSMAD3 interactions

MAGI2 FLI1 BPTF NCOA6 SMARCC1 NCOA1 RUNX2 TRIM24 CREBBP

1.73e-04447909int:SMAD3
InteractionTERF2IP interactions

BPTF NCOR2 NCOA6 WDR33 CDK12 CIZ1 SMARCC1 TRIM24 CREBBP TOR1AIP1

1.76e-045529010int:TERF2IP
InteractionTRIM33 interactions

BPTF RANBP2 KLC2 SMARCC1 SSBP2 SSBP4 TRIM24 CREBBP KLHL20

1.91e-04453909int:TRIM33
InteractionHNF1B interactions

BPTF NCOR2 KMT2C SMARCC1 TRIM24 CREBBP

2.10e-04190906int:HNF1B
InteractionMLLT1 interactions

RNF123 CDK12 SMARCC1 SMARCD2 TRIM24

2.27e-04123905int:MLLT1
InteractionARID1A interactions

FLI1 BPTF SRGAP3 SMARCC1 NCOA1 SMARCD2 CREBBP

2.37e-04276907int:ARID1A
InteractionKLF5 interactions

NCOR2 KMT2C NCOA6 SMARCD2 TRIM24 CREBBP

2.41e-04195906int:KLF5
InteractionPML interactions

SYNRG NCOR2 RANBP2 RNF123 ZSCAN21 GTSE1 ZNF207 CLINT1 RUNX2 TRIM24 CREBBP ZYX KLHL20

2.49e-049339013int:PML
InteractionJUN interactions

NCOR2 KMT2C NCOA6 WIPF1 SMARCC1 NCOA1 CLINT1 RUNX2 CREBBP

2.51e-04470909int:JUN
InteractionPYGO1 interactions

BCL9L SSBP2 SSBP4

2.60e-0428903int:PYGO1
InteractionARX interactions

GTSE1 KLC2 CLINT1

2.60e-0428903int:ARX
InteractionPLEKHG4B interactions

DYRK1B CAMSAP3 ZYX

2.60e-0428903int:PLEKHG4B
InteractionVDR interactions

NCOR2 NCOA6 NCOA1 TRIM24 CREBBP

2.63e-04127905int:VDR
InteractionPOU5F1 interactions

ZNF462 BPTF NCOR2 NCAPD3 WDR33 SCAF8 SMARCC1 CTBP2 ATXN10 TRIM24

2.76e-045849010int:POU5F1
InteractionTNIK interactions

ZNF462 MAGI2 NCOR2 SRGAP3 CTBP2 LRRC7 SOS1 SYNGAP1

3.05e-04381908int:TNIK
InteractionKLF15 interactions

NCOR2 KMT2C PYGO2 NCOA1 MRPL38 TRIM24 CREBBP

3.21e-04290907int:KLF15
InteractionSMAD2 interactions

BPTF KMT2C NCOA6 RNF123 SMARCC1 SMARCD2 RUNX2 CREBBP

3.27e-04385908int:SMAD2
InteractionTLX3 interactions

BCL9L NCOR2 KMT2C NCOA6 PYGO2 TRIM24 SYNGAP1

3.27e-04291907int:TLX3
InteractionCREBBP interactions

NCOR2 NCOA6 PYGO2 DYRK1B SMARCC1 NCOA1 CTBP2 RUNX2 TRIM24 CREBBP

3.37e-045999010int:CREBBP
InteractionNR1H4 interactions

NCOR2 NCOA6 NCOA1

3.89e-0432903int:NR1H4
InteractionYWHAG interactions

SYNRG NCOA6 TTBK1 CARMIL2 CDK12 SAMD4B GTSE1 RALGAPB CAMSAP3 KLC2 CLINT1 GNAS TESK1 AQR SYNGAP1

3.95e-0412489015int:YWHAG
InteractionSLC45A1 interactions

CARMIL2 SLC45A1

4.08e-047902int:SLC45A1
InteractionYWHAE interactions

SYNRG NCOR2 CARMIL2 SYN3 CDK12 SRGAP3 SAMD4B GTSE1 RALGAPB AGXT CAMSAP3 KLC2 RIMS2 ZYX SYNGAP1

4.22e-0412569015int:YWHAE
InteractionFOXQ1 interactions

NCOR2 RANBP2 CTBP2 SSBP2 CREBBP

4.26e-04141905int:FOXQ1
InteractionEP300 interactions

NCOR2 NCOA6 ZNF469 CDK12 DYRK1B KLC2 SMARCC1 NCOA1 CTBP2 SSBP2 CLINT1 RUNX2 SSBP4 TRIM24 CREBBP ZYX

4.36e-0414019016int:EP300
InteractionNUP43 interactions

ZNF462 BCL9L BPTF NCOR2 NCOA6 RANBP2 CDK12 CIZ1 KLC2 SMARCC1

4.71e-046259010int:NUP43
InteractionCDK8 interactions

ZSCAN21 CDK12 SMARCC1 CREBBP PBXIP1 AQR

4.81e-04222906int:CDK8
InteractionNCOA6 interactions

NCOR2 KMT2C NCOA6 NCOA1 CREBBP

4.84e-04145905int:NCOA6
InteractionELF5 interactions

BPTF KMT2C GTSE1 SMARCD2 TRIM24

5.15e-04147905int:ELF5
InteractionSH3KBP1 interactions

WIPF1 GTSE1 CIZ1 KLC2 ITGA3 SOS1 SYNGAP1

5.26e-04315907int:SH3KBP1
InteractionPHOX2A interactions

CREBBP ATF6B

5.43e-048902int:PHOX2A
InteractionSNRNP40 interactions

ZNF462 BCL9L NCOR2 CDK12 SCAF8 CIZ1 SMARCC1 ZNF207 TRIM24 AQR

5.46e-046379010int:SNRNP40
InteractionPGR interactions

BPTF NCOR2 NCOA1 TRIM24

5.46e-0484904int:PGR
InteractionHOXB2 interactions

NCOA1 TRIM24 CREBBP

5.53e-0436903int:HOXB2
InteractionADGRB1 interactions

MAGI2 RNF123 LRRC7

5.53e-0436903int:ADGRB1
InteractionEGLN3 interactions

NCOR2 NCAPD3 RANBP2 SELENOK CDK12 SCAF8 SAMD4B GTSE1 CTBP2 CLINT1 ATXN10 GNAS RBBP8NL CREBBP TOR1AIP1

5.86e-0412969015int:EGLN3
InteractionBCL9 interactions

BCL9L PYGO2 SSBP2 SSBP4

5.97e-0486904int:BCL9
InteractionKLF1 interactions

FLI1 SMARCC1 CREBBP

6.00e-0437903int:KLF1
InteractionDNM1 interactions

CTBP2 MRPL38 CLINT1 RUNX2 SYNGAP1

7.15e-04158905int:DNM1
InteractionEYA4 interactions

NCOR2 WDR33 SOBP CIZ1 NCOA1 CREBBP

7.73e-04243906int:EYA4
InteractionPTPN23 interactions

SYNRG KLC2 CTBP2 CLINT1 ZYX

8.00e-04162905int:PTPN23
InteractionISL1 interactions

BCL9L SSBP2 SSBP4

8.12e-0441903int:ISL1
GeneFamilyPHD finger proteins

BPTF KMT2C PYGO2 TRIM24

2.41e-049061488
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

NCOA1 CREBBP

1.47e-0317612486
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

FLI1 BPTF SYNRG KMT2C RANBP2 WIPF1 SCAF8 SRGAP3 RALGAPB NCOA1 GNAS RUNX2 SSBP4 CREBBP TOR1AIP1 PBXIP1 ZYX SOS1

4.37e-0614929318M40023
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

BPTF NCOR2 RANBP2 SCAF8 NCOA1 CTBP2 SSBP2 CLINT1 TRIM24 CREBBP KLHL20 AQR SOS1

1.02e-058569313M4500
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 BCL9L NCOR2 SAMD4B ITGA3 TESK1 PBXIP1

1.29e-07186937bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

BOC COL4A6 BPTF DMRT3 EFNB3 TUG1 TRIM24

2.05e-07199937358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MAGI2 KMT2C NCOA1 SSBP2 MAML3 SOS1

3.84e-0619993694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell368C-Fibroblasts-Fibroblast-H-|368C / Donor, Lineage, Cell class and subclass (all cells)

EFNB3 GPR173 PRDM15 ABCC10 SYNGAP1

1.69e-05152935dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCell368C-Fibroblasts-Fibroblast-H|368C / Donor, Lineage, Cell class and subclass (all cells)

EFNB3 GPR173 PRDM15 ABCC10 SYNGAP1

1.69e-051529359f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCell368C-Fibroblasts-Fibroblast-H|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EFNB3 GPR173 PRDM15 ABCC10 SYNGAP1

1.79e-05154935f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell368C-Fibroblasts-Fibroblast-H-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EFNB3 GPR173 PRDM15 ABCC10 SYNGAP1

1.79e-0515493566065c0763c83d98084ca6969694c3af37e43274
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

RNF123 SRGAP3 SMARCC1 MAML3 SYNGAP1

2.57e-0516693532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RNF123 SOBP CC2D1B SSBP2 SOS1

3.05e-0517293584d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MAGI2 EVA1C COL16A1 SRGAP3 ABCC10

3.50e-0517793530f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

NCOA6 DYRK1B CTBP2 ATF6B PBXIP1

3.79e-05180935974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

NCOA6 DYRK1B CTBP2 ATF6B PBXIP1

3.79e-05180935703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOR2 SAMD4B ITGA3 TESK1 PBXIP1

4.78e-05189935965e0e388251e7318f8b463816dc96ccb4658677
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 NCOR2 COL16A1 ITGA3 PBXIP1

5.02e-051919352f733d510a4862565a817f59829d8387d7ea26d9
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLI1 NCOR2 COL16A1 ITGA3 PBXIP1

5.02e-051919358691eba35793e4e90f93d50c2145847ee51289f7
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

BPTF SYNRG RANBP2 SMARCC1 AQR

5.28e-05193935abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C DYRK1B SMARCD2 ZNF207 SSBP2

5.28e-05193935a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCellSevere-CD8+_T_activated|Severe / Disease group and Cell class

UBXN11 WIPF1 OTOF ZYX LGALS3

5.82e-05197935bb1e3e1d841c2c7141eb1099e7755860b168b6fc
ToppCellSevere-CD8+_T_activated|World / Disease group and Cell class

UBXN11 WIPF1 OTOF ZYX LGALS3

5.96e-051989355ff98c9b6c8c6863767b76c7745f263568f86acc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6|World / Primary Cells by Cluster

MAGI2 BPTF NCOA1 SSBP2 RIMS2

6.10e-051999351b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal|World / Primary Cells by Cluster

MAGI2 BPTF NCOA1 SSBP2 RIMS2

6.10e-051999354bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

FLI1 BPTF KMT2C SLCO2B1 DOCK6

6.25e-05200935dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
DrugPromazine hydrochloride [53-60-1]; Up 200; 12.4uM; PC3; HT_HG-U133A

COL16A1 WDR33 SLCO2B1 AGXT RIMS2 TESK1 KIF17 PBXIP1

1.53e-062009283752_UP
Diseaseschizophrenia (implicated_via_orthology)

SRGAP3 BLOC1S1 RIMS2 SYNGAP1

6.19e-0568924DOID:5419 (implicated_via_orthology)
DiseaseHyperoxaluria

AGXT SLC26A1

2.66e-048922C0020500
DiseaseEwings sarcoma

FLI1 CIZ1

2.66e-048922C0553580
DiseaseAdenoid Cystic Carcinoma

MAGI2 KMT2C CREBBP MAML3

2.76e-04100924C0010606
DiseaseLiver Diseases, Parasitic

KMT2C GNAS

3.41e-049922C0023897
DiseaseCoffin-Siris syndrome (implicated_via_orthology)

SMARCC1 SMARCD2

3.41e-049922DOID:1925 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

CIZ1 SMARCC1 SMARCD2 CTBP2 CREBBP

3.70e-04195925DOID:1574 (implicated_via_orthology)
DiseaseBladder Neoplasm

BPTF KMT2C CALHM1 CREBBP

9.82e-04140924C0005695
DiseaseMalignant neoplasm of urinary bladder

BPTF KMT2C CALHM1 CREBBP

1.01e-03141924C0005684
Diseaseautism spectrum disorder (implicated_via_orthology)

SYN3 RIMS2 CREBBP SYNGAP1

1.33e-03152924DOID:0060041 (implicated_via_orthology)
Diseasevital capacity

FLI1 CACNA1S NCOR2 NCOA6 CDK12 AGXT NCOA1 SMARCD2 RUNX2 SSBP4 TRIM24

1.61e-0312369211EFO_0004312
DiseaseCraniosynostosis

ZNF462 RUNX2

1.76e-0320922C0010278
Diseasecardioembolic stroke

NCOR2 TTBK1 WIPF1 PBXIP1

2.00e-03170924EFO_1001976
Diseaseneuroimaging measurement, brain volume measurement

BPTF CTBP2 MYEOV ATXN10 RUNX2

2.04e-03286925EFO_0004346, EFO_0006930
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C GNAS

2.54e-0324922C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C GNAS

2.54e-0324922C3805278
Diseasephysical activity

MAGI2 SAMD4B LRRC7

2.66e-0388923EFO_0003940
DiseaseIntellectual Disability

ZNF462 BPTF KMT2C SRGAP3 GNAS SYNGAP1

2.78e-03447926C3714756
Diseasemacula measurement

BPTF DYRK1B MYEOV SYNGAP1

2.94e-03189924EFO_0008375
DiseaseCholangiocarcinoma

KMT2C GNAS

2.98e-0326922C0206698
DiseaseNeurodevelopmental Disorders

KMT2C SRGAP3 SYNGAP1

3.11e-0393923C1535926

Protein segments in the cluster

PeptideGeneStartEntry
PLTPQPIQMPGRPLR

GNAS

396

P84996
SGPQGPRRTPTMPQE

CDK12

1236

Q9NYV4
GPVGIPSPRRPMSNL

COL4A6

951

Q14031
IRPQIMNGPLHPRPL

CTBP2

21

P56545
RGPGVPSPQPDVTML

BLOC1S1

16

P78537
SQPLGPRRPMRPVGH

COL16A1

191

Q07092
MAAPRPPPARLSGVM

ATXN10

1

Q9UBB4
AGPLPRMDLPLAGQP

CARMIL2

1001

Q6F5E8
VRPPNGPLSLPVNRM

CREBBP

701

Q92793
PMPGLPRPVISMQAQ

CREBBP

2031

Q92793
PPLRLGQEEPPLMGN

CALHM1

311

Q8IU99
RAGMQPGLTMVVGPP

AQR

811

O60306
MRGRRGRPPKQPAAP

BPTF

1

Q12830
MVEAAPPGPGPLRRT

CAMSAP3

1

Q9P1Y5
ALRTRMTGGRPPLPP

DYRK1B

591

Q9Y463
FVQPMPGEGLRPSLP

RANBP2

1006

P49792
QRGTLLPPLLPGPMA

ABCC10

156

Q5T3U5
MRLQAGVMASPPPPG

NCOR2

2466

Q9Y618
GPRHTDPMRRPPQGL

KMT2C

2601

Q8NEZ4
PLAIMERPPPVMVNG

MAGI2

526

Q86UL8
PVRPQTNALIGGPMP

CLINT1

536

Q14677
PRPQAPPRLQSLMGT

MAML3

941

Q96JK9
VPPGNIPQRPDRLPM

LRRC7

746

Q96NW7
VPYNLPLPGGVVPRM

LGALS3

116

P17931
PPVLMPRGNVGTPLR

GPATCH3

186

Q96I76
MGPGPSRAPRAPRLM

ITGA3

1

P26006
MGPSRLVRGPRPQGM

P3R3URF

1

A0A087WWA1
VRRTGQVGPTMHPPP

MYEOV

276

Q96EZ4
RMGPAMLRPALPAGP

GTSE1

356

Q9NYZ3
GGTPQEPPNPRMKRA

KLC2

566

Q9H0B6
GPMISPTMGQPPRAE

PYGO2

191

Q9BRQ0
MSAPVGPRGRLAPIP

RIMS2

1

Q9UQ26
MGIQGQVLRPPGPSP

NCOA6

781

Q14686
RGQPTPGEMLPSLPV

RBBP8NL

376

Q8NC74
MLLPGRARQPPTPQP

EVA1C

1

P58658
LPQERPLMQGPRTRP

KLHL20

296

Q9Y2M5
MLRGQPALPRPPTSV

BOC

441

Q9BWV1
RLPQLMAPTPPGLRN

DOCK6

2021

Q96HP0
LTQRAMPRGQAPPAP

CACNA1S

1726

Q13698
MGGPVSQPPRAPLQR

DMRT3

11

Q9NQL9
GPPPPNMTTNERRVI

FLI1

111

Q01543
PPMGQSGLREVDPPM

BCL9L

751

Q86UU0
MMPGPRPRKGPQARG

CC2D1B

1

Q5T0F9
VRGMNLPAPPGVTPD

CC2D1B

706

Q5T0F9
RGPMPPTLLGIRQNG

GPR173

251

Q9NS66
PRVARPFGGNLRMPP

KLF17

141

Q5JT82
PRGGAVPRKPVSEMP

EFNB3

171

Q15768
MPMLDIRPGLIPQAP

SCAF8

921

Q9UPN6
MLQQPGPRPGRQQPS

SLC45A1

1

Q9Y2W3
DQMQRLLQGPAPRPP

PERM1

136

Q5SV97
VPQLSPRPGALRPML

PRR18

221

Q8N4B5
RGPIMPVPMGIRPVL

OTOF

1116

Q9HC10
MQGLPDPPSQRGIIP

KIF17

101

Q9P2E2
RIPHPSMRVGVPPQN

RUNX2

251

Q13950
SMRVGVPPQNPRPSL

RUNX2

256

Q13950
GLMEPPGPSTPIVQR

SYN3

76

O14994
QRMTPPRGMVPLGPQ

SSBP2

176

P81877
LGPGPSNLPPRIMAA

AGXT

26

P21549
VAGGIRPPQAGLMPM

SYNRG

31

Q9UMZ2
PSSGLPVQMGNPRLP

NCOA1

1146

Q15788
PRPRVQPMRVARGGP

PRDM15

111

P57071
KSPGVRPSNPRPGTM

SOS1

1036

Q07889
MPGNILGPRVPLTAP

SMARCC1

1056

Q92922
VPQAQPPMPAQRRGL

SMARCD2

121

Q92925
RPERKSIVPAPMPGN

ATF6B

301

Q99941
PPPQVRGSVMPSVIR

NCAPD3

906

P42695
PPGRPQEMGPKLQAR

CNGB1

196

Q14028
RQSLLGPPPVGVPMN

CIZ1

156

Q9ULV3
PPGNPPRRMGRINHL

SELENOK

66

Q9Y6D0
RRPAPVGLPNPRMQG

TRIM24

486

O15164
IPRPIGLRMPMPVAA

TTBK1

1156

Q5TCY1
LGMAPVLGPRPPQEQ

ZSCAN21

6

Q9Y5A6
VLGPRPPQEQVGPLM

ZSCAN21

11

Q9Y5A6
EQPPLQPSPVMTRRG

TOR1AIP1

136

Q5JTV8
PAPMTQPGPLRLELR

ZP1

396

P60852
GRRTPPLGPMPNSDI

MRPL38

26

Q96DV4
RRRGREAGPPQPMVP

PBXIP1

161

Q96AQ6
RLAGAQLRPPPMRPV

SRGAP3

1046

O43295
PRPQPVVLRGPSAEM

SYNGAP1

741

Q96PV0
FPMPPRALPPGRMGL

SAMD4B

576

Q5PRF9
GFMPPQVPEPRLMQR

SLC26A1

326

Q9H2B4
MGPRIGPAGEVPQVP

SLCO2B1

1

O94956
LGVPPRSPPMVMTNR

SOBP

376

A7XYQ1
RSPPMVMTNRGPVPL

SOBP

381

A7XYQ1
MQALAVGGPLPLPRP

RNF123

656

Q5XPI4
PSMGGPMQRVTPPRG

SSBP4

191

Q9BWG4
MARPPPLPGLVGRRN

TUG1

1

A0A6I8PU40
MLGFPPGRPQLPVQL

ZNF211

1

Q13398
GHRSGPPEPQRNRMP

WIPF1

156

O43516
RRMETALPGPGPPAV

TESK1

446

Q15569
MGMLAPGPLQGRRPR

SNHG28

1

P0DPA3
PSSRMRKLPQGRPVP

RALGAPB

1321

Q86X10
MPGERPRGAPPPTMT

ZNF469

1

Q96JG9
PRPPMGMRPPVMSQG

ZNF207

461

O43670
PPPAPGAQRAQMGRV

ZYX

46

Q15942
MMRGVEGPQGSPRPP

ZNF462

1156

Q96JM2
PQGSMLGPPQELRGP

WDR33

841

Q9C0J8
TRKVPLPSEPMNPGR

UBXN11

11

Q5T124