Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionCDP phosphatase activity

ENTPD6 ENTPD5

6.23e-054652GO:0036384
GeneOntologyMolecularFunctionIDP phosphatase activity

ENTPD6 ENTPD5

1.04e-045652GO:1990003
GeneOntologyMolecularFunctionNAD+-protein-cysteine ADP-ribosyltransferase activity

PARP6 PARP8

1.55e-046652GO:0140803
GeneOntologyMolecularFunctionATP-dependent chromatin remodeler activity

CHD5 CHD3 CHD4

2.36e-0437653GO:0140658
GeneOntologyMolecularFunctionUDP phosphatase activity

ENTPD6 ENTPD5

3.70e-049652GO:0045134
GeneOntologyMolecularFunctiontestosterone dehydrogenase [NAD(P)+] activity

DHRS9 SRD5A2

5.63e-0411652GO:0030283
GeneOntologyMolecularFunctionGDP phosphatase activity

ENTPD6 ENTPD5

6.74e-0412652GO:0004382
GeneOntologyMolecularFunctionpyrophosphatase activity

CHD5 ENTPD6 ENTPD5 ENPP5 CHD3 CHD4 DNAH8 GNL1 DNAH7

1.51e-03839659GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

CHD5 ENTPD6 ENTPD5 ENPP5 CHD3 CHD4 DNAH8 GNL1 DNAH7

1.53e-03840659GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

CHD5 ENTPD6 ENTPD5 ENPP5 CHD3 CHD4 DNAH8 GNL1 DNAH7

1.53e-03840659GO:0016818
GeneOntologyMolecularFunctionmicrotubule motor activity

APPBP2 DNAH8 DNAH7

1.54e-0370653GO:0003777
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH8 DNAH7

1.54e-0318652GO:0008569
GeneOntologyMolecularFunctionhistone binding

CHD5 CHD3 CHD4 SSRP1 ZZEF1

1.71e-03265655GO:0042393
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

ENTPD6 ENTPD5

1.91e-0320652GO:0017110
GeneOntologyMolecularFunctionzinc ion binding

CAD TUT7 PRICKLE2 ENPP5 CPB1 CHD3 CHD4 PPARG ZZEF1

2.28e-03891659GO:0008270
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

PARP6 CAD PDK2 HIPK1 PARP8 TUT7 FN3KRP AGK TWF1

3.22e-03938659GO:0016772
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

CHD5 ENTPD6 ENTPD5 CHD3 CHD4 DNAH8 GNL1 DNAH7

3.55e-03775658GO:0017111
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH8 DNAH7

3.73e-0328652GO:0051959
GeneOntologyMolecularFunctionNAD+-protein poly-ADP-ribosyltransferase activity

PARP6 PARP8

3.73e-0328652GO:0003950
GeneOntologyCellularComponentCHD-type complex

CHD5 CHD3 CHD4

2.07e-0517673GO:0090545
GeneOntologyCellularComponentNuRD complex

CHD5 CHD3 CHD4

2.07e-0517673GO:0016581
DomainCHDCT2

CHD5 CHD3 CHD4

4.02e-083653PF08074
DomainCHDNT

CHD5 CHD3 CHD4

4.02e-083653PF08073
DomainDUF1086

CHD5 CHD3 CHD4

4.02e-083653IPR009462
DomainDUF1087

CHD5 CHD3 CHD4

4.02e-083653IPR009463
DomainCHD_N

CHD5 CHD3 CHD4

4.02e-083653IPR012958
DomainCHD_C2

CHD5 CHD3 CHD4

4.02e-083653IPR012957
DomainDUF1087

CHD5 CHD3 CHD4

4.02e-083653PF06465
DomainDUF1086

CHD5 CHD3 CHD4

4.02e-083653PF06461
DomainDUF1087

CHD5 CHD3 CHD4

4.02e-083653SM01147
DomainDUF1086

CHD5 CHD3 CHD4

4.02e-083653SM01146
DomainHMG_box_dom

CHD5 CHD3 CHD4 SSRP1

7.71e-0565654IPR009071
DomainChromo_domain

CHD5 CHD3 CHD4

7.73e-0524653IPR023780
DomainChromo

CHD5 CHD3 CHD4

9.88e-0526653PF00385
DomainCHROMO_1

CHD5 CHD3 CHD4

1.24e-0428653PS00598
DomainCHROMO_2

CHD5 CHD3 CHD4

1.24e-0428653PS50013
DomainSNF2_N

CHD5 CHD3 CHD4

1.86e-0432653IPR000330
DomainChromodomain-like

CHD5 CHD3 CHD4

1.86e-0432653IPR016197
DomainSNF2_N

CHD5 CHD3 CHD4

1.86e-0432653PF00176
DomainChromo/shadow_dom

CHD5 CHD3 CHD4

2.04e-0433653IPR000953
DomainCHROMO

CHD5 CHD3 CHD4

2.04e-0433653SM00298
DomainDNA/RNA_helicase_DEAH_CS

CHD5 CHD3 CHD4

2.43e-0435653IPR002464
DomainDEAH_ATP_HELICASE

CHD5 CHD3 CHD4

3.11e-0438653PS00690
DomainGDA1_CD39_NTPase

ENTPD6 ENTPD5

3.29e-048652IPR000407
DomainGDA1_CD39

ENTPD6 ENTPD5

3.29e-048652PF01150
DomainGDA1_CD39_NTPASE

ENTPD6 ENTPD5

3.29e-048652PS01238
Domain-

CHD5 CHD3 SSRP1

9.28e-04556531.10.30.10
DomainDynein_heavy_chain_D4_dom

DNAH8 DNAH7

1.06e-0314652IPR024317
DomainDynein_HC_stalk

DNAH8 DNAH7

1.06e-0314652IPR024743
DomainDynein_heavy_dom-2

DNAH8 DNAH7

1.06e-0314652IPR013602
DomainDHC_N2

DNAH8 DNAH7

1.06e-0314652PF08393
DomainMT

DNAH8 DNAH7

1.06e-0314652PF12777
DomainAAA_8

DNAH8 DNAH7

1.06e-0314652PF12780
DomainDHC_fam

DNAH8 DNAH7

1.22e-0315652IPR026983
DomainDynein_heavy_dom

DNAH8 DNAH7

1.22e-0315652IPR004273
DomainDynein_heavy

DNAH8 DNAH7

1.22e-0315652PF03028
DomainZinc_finger_PHD-type_CS

CHD5 CHD3 CHD4

1.51e-0365653IPR019786
DomainPoly(ADP-ribose)pol_cat_dom

PARP6 PARP8

1.57e-0317652IPR012317
DomainPARP_CATALYTIC

PARP6 PARP8

1.57e-0317652PS51059
DomainPARP

PARP6 PARP8

1.57e-0317652PF00644
Domain-

PARP6 PARP8

1.57e-03176523.90.228.10
DomainLH2

LOXHD1 PKD1L2

1.76e-0318652SM00308
DomainPHD

CHD5 CHD3 CHD4

2.27e-0375653PF00628
DomainPLAT

LOXHD1 PKD1L2

2.40e-0321652PS50095
Domain-

LOXHD1 PKD1L2

2.40e-03216522.60.60.20
DomainPLAT

LOXHD1 PKD1L2

2.40e-0321652PF01477
DomainPLAT/LH2_dom

LOXHD1 PKD1L2

2.40e-0321652IPR001024
DomainZnf_PHD-finger

CHD5 CHD3 CHD4

2.63e-0379653IPR019787
DomainWGR_domain

PARP6 PARP8

3.13e-0324652IPR008893
DomainPHD

CHD5 CHD3 CHD4

3.69e-0389653SM00249
DomainZnf_PHD

CHD5 CHD3 CHD4

3.93e-0391653IPR001965
DomainZF_PHD_2

CHD5 CHD3 CHD4

4.43e-0395653PS50016
DomainZF_PHD_1

CHD5 CHD3 CHD4

4.57e-0396653PS01359
DomainATP_grasp_subdomain_2

CAD TTLL4

5.20e-0331652IPR013816
DomainHelicase_C

CHD5 CHD3 CHD4

6.17e-03107653PF00271
DomainHELICc

CHD5 CHD3 CHD4

6.17e-03107653SM00490
DomainHelicase_C

CHD5 CHD3 CHD4

6.33e-03108653IPR001650
DomainHELICASE_CTER

CHD5 CHD3 CHD4

6.50e-03109653PS51194
DomainHELICASE_ATP_BIND_1

CHD5 CHD3 CHD4

6.50e-03109653PS51192
DomainDEXDc

CHD5 CHD3 CHD4

6.50e-03109653SM00487
DomainHelicase_ATP-bd

CHD5 CHD3 CHD4

6.66e-03110653IPR014001
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_BROWN_AND_BEIGE_ADIPOCYTE_DIFFERENTIATION

CHD3 CHD4 PPARG

1.98e-0431523M48258
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

HIPK1 PRR5 CHD3 CHD4 SSRP1

2.74e-04157525MM15226
PathwayREACTOME_REGULATION_OF_TP53_ACTIVITY

HIPK1 PRR5 CHD3 CHD4 SSRP1

2.99e-04160525M27498
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD6 ENTPD5

3.68e-048522M27737
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD6 ENTPD5

3.68e-048522MM15486
Pubmed

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.

CHD5 SPTBN1 CHD4 SSRP1

7.07e-073667429089422
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

CAD CHD5 CHD3 CHD4 SSRP1

9.32e-079167520362542
Pubmed

DLX1 and the NuRD complex cooperate in enhancer decommissioning and transcriptional repression.

CHD5 CHD3 CHD4

3.06e-061567335695185
Pubmed

Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.

CHD3 CHD4

3.66e-0626727560064
Pubmed

The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.

CHD3 CHD4

3.66e-0626727575689
Pubmed

cDNA cloning and chromosomal mapping of a mouse gene with homology to NTPases.

ENTPD6 ENTPD5

3.66e-0626729457681
Pubmed

Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development.

CHD3 CHD4

3.66e-06267235568926
Pubmed

Two forms of the major antigenic protein of the dermatomyositis-specific Mi-2 autoantigen.

CHD3 CHD4

3.66e-0626728843877
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

PACS1 FNDC3B CEP78 TTC28 SGPL1 TUT7 AFDN CHD3 ZZEF1

4.29e-0665067938777146
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

CHD5 CHD3 CHD4

4.56e-061767327806305
Pubmed

The chromatin-remodeling enzyme CHD3 plays a role in embryonic viability but is dispensable for early vascular development.

CHD3 CHD4

1.10e-05367232658897
Pubmed

Characterization of the CHD family of proteins.

CHD3 CHD4

2.19e-0546729326634
Pubmed

The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster.

ENTPD6 ENTPD5

2.19e-0546729676430
Pubmed

Cloning and mapping of a human and mouse gene with homology to ecto-ATPase genes.

ENTPD6 ENTPD5

2.19e-0546729271669
Pubmed

Genetic variants on chromosome 1q41 influence ocular axial length and high myopia.

PARP8 SPTBN1

2.19e-05467222685421
Pubmed

NAB2 represses transcription by interacting with the CHD4 subunit of the nucleosome remodeling and deacetylase (NuRD) complex.

CHD3 CHD4

2.19e-05467216574654
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

CAD SGPL1 RPS5 CHD5 SPTBN1 TUT7 AGK BUD13 SSRP1 FKBP4 TWF1

2.64e-051257671136526897
Pubmed

Inhibition of ubiquitin ligase F-box and WD repeat domain-containing 7α (Fbw7α) causes hepatosteatosis through Krüppel-like factor 5 (KLF5)/peroxisome proliferator-activated receptor γ2 (PPARγ2) pathway but not SREBP-1c protein in mice.

KLF5 PPARG

3.64e-05567221911492
Pubmed

Proteomic analysis of mouse thymoma EL4 cells treated with bis(tri-n-butyltin)oxide (TBTO).

SPTBN1 CHD4

3.64e-05567219552622
Pubmed

Identification of the BRD1 interaction network and its impact on mental disorder risk.

CHD5 CHD3 CHD4

4.28e-053567327142060
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

CHD5 CHD3 CHD4 SSRP1

4.82e-0510367432744500
Pubmed

Chromatin remodeling proteins interact with pericentrin to regulate centrosome integrity.

CHD3 CHD4

5.46e-05667217626165
Pubmed

Cross-linking mass spectrometry reveals the structural topology of peripheral NuRD subunits relative to the core complex.

CHD5 CHD3 CHD4

5.49e-053867333283408
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

NTAN1 RPS5 SPTBN1 AGK AFDN CHD4 SSRP1 GNL1

6.61e-0571167833022573
Pubmed

SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-delta.

KLF5 PPARG

7.63e-05767218500350
Pubmed

The PARP superfamily.

PARP6 PARP8

1.02e-04867215273990
Pubmed

Mammalian chromodomain proteins: their role in genome organisation and expression.

CHD3 CHD4

1.02e-04867210655032
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

CEP78 RPS5 TUT7 AGK BUD13 CHD3 CHD4 SSRP1

1.04e-0475967835915203
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

PACS1 SPTBN1 BUD13 AFDN CHD3 CHD4 SNX33 SSRP1

1.19e-0477467815302935
Pubmed

FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.

RPS5 CHD3 CHD4 SSRP1 DNAH7

1.19e-0424867527926873
Pubmed

Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.

BUD13 CHD3 CHD4

1.76e-045667326919559
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

CHD5 SPTBN1 CHD3 CHD4 SSRP1

1.80e-0427167532433965
Pubmed

The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.

RPS5 CHD5 SPTBN1 CHD4

1.91e-0414767428977470
Pubmed

Normal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glands.

FA2H PPARG

1.99e-041167221628453
Pubmed

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.

CHD3 CHD4

1.99e-041167210204490
Pubmed

Breast cancer: a candidate gene approach across the estrogen metabolic pathway.

SRD5A2 PPARG

1.99e-041167217588204
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

CAD RPS5 SPTBN1 AGK CHD4 SSRP1 FKBP4

2.27e-0463867733239621
Pubmed

NURD, a novel complex with both ATP-dependent chromatin-remodeling and histone deacetylase activities.

CHD3 CHD4

2.38e-04126729885572
Pubmed

NuRD suppresses pluripotency gene expression to promote transcriptional heterogeneity and lineage commitment.

CHD3 CHD4

2.38e-041267222560079
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

SPTBN1 CHD3 CHD4 FKBP4

2.40e-0415667437108203
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TTC28 PARP8 SPTBN1 PRR5 AFDN SSRP1 DNAH7 TWF1

2.45e-0486167836931259
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FNDC3B CAD SGPL1 RPS5 SPTBN1 TUT7 AFDN CHD4 SNX33 SSRP1

2.53e-041353671029467282
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CAD RPS5 SPTBN1 TUT7 AFDN CHD4 FKBP4

2.61e-0465367722586326
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

APPBP2 CAD SGPL1 RPS5 AGK CHD3 CHD4

2.66e-0465567735819319
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TTC28 SGPL1 CHD5 BUD13 CHD3 CHD4 ITGA3 SSRP1 ZZEF1

2.81e-04111667931753913
Pubmed

LSD1 is a subunit of the NuRD complex and targets the metastasis programs in breast cancer.

CHD3 CHD4

2.81e-041367219703393
Pubmed

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.

SOCS2 TTC28 ERRFI1 PPARG

2.83e-0416367423333304
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH8 DNAH7

3.28e-04146729373155
Pubmed

The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny.

CHD3 CHD4

3.28e-041467217360773
Pubmed

MBD2/NuRD and MBD3/NuRD, two distinct complexes with different biochemical and functional properties.

CHD3 CHD4

3.28e-041467216428440
Pubmed

NuRD-ZNF827 recruitment to telomeres creates a molecular scaffold for homologous recombination.

CHD3 CHD4

3.28e-041467225150861
Pubmed

Human cytomegalovirus UL29/28 protein interacts with components of the NuRD complex which promote accumulation of immediate-early RNA.

CHD3 CHD4

3.28e-041467220585571
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

ZNF716 TTC28 CHD3 DNAH7

3.32e-0417067423314748
Pubmed

The chromatin remodeling factor CHD5 is a transcriptional repressor of WEE1.

CHD5 CHD4

3.78e-041567225247294
Pubmed

Chromatin deacetylation by an ATP-dependent nucleosome remodelling complex.

CHD3 CHD4

3.78e-04156729804427
Pubmed

NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development.

CHD3 CHD4

3.78e-041567219927129
Pubmed

Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.

TTC28 KLF5 FA2H

3.86e-047367325086665
Pubmed

BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites.

CAD SSRP1 FKBP4

3.86e-047367332347575
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PACS1 CAD SGPL1 RPS5 SPTBN1 ARHGAP44 PRICKLE2 AFDN CHD3 TWF1

3.95e-041431671037142655
Pubmed

p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis.

CHD3 CHD4

4.31e-041667221930775
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

PARP6 PARP8

4.31e-041667225043379
Pubmed

RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation.

CHD3 CHD4

4.31e-041667230760870
Pubmed

A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order.

TMEM232 ENTPD6

4.31e-041667222036096
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

FNDC3B SGPL1 AFDN SNX33 HACD2 ABHD16A FKBP4

4.65e-0471967735337019
Pubmed

Genome-wide analysis of sex-specific differences in the mother-child PELAGIE cohort exposed to organophosphate metabolites.

PDK2 PPARG

4.88e-041767237198424
Pubmed

Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development.

CHD3 CHD4

5.48e-041867223201013
Pubmed

The dermatomyositis-specific autoantigen Mi2 is a component of a complex containing histone deacetylase and nucleosome remodeling activities.

CHD3 CHD4

5.48e-04186729790534
Pubmed

A candidate X-linked mental retardation gene is a component of a new family of histone deacetylase-containing complexes.

CHD3 CHD4

5.48e-041867212493763
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

SPTBN1 ITGA3

5.48e-041867212119179
Pubmed

Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.

CHD3 CHD4

5.48e-041867210444591
Pubmed

Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse.

PARP6 LOXHD1

5.48e-041867233087486
Pubmed

LSD1-mediated epigenetic modification is required for TAL1 function and hematopoiesis.

CHD3 CHD4

5.48e-041867219497860
Pubmed

Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways.

FMO2 ENTPD5 PRICKLE2 GULP1

5.79e-0419767421386911
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

TULP4 SPTBN1 PRICKLE2 AFDN

5.79e-0419767436604605
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

SOCS2 FNDC3B TULP4 TUT7

5.90e-0419867420881960
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

CAD AFDN CHD3 CHD4

6.36e-0420267424639526
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SGPL1 BUD13 HERC3 PKD1L2 FAM43A

6.68e-0436167526167880
Pubmed

Identification of Protor as a novel Rictor-binding component of mTOR complex-2.

PRR5 ABHD16A

6.79e-042067217461779
Pubmed

A cohesin-RAD21 interactome.

CAD RPS5 CHD4 GNL1

7.10e-0420867422145905
Pubmed

High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.

APPBP2 KLF5 PARP8 ARHGAP44 CHD3 HACD2 MAPKBP1 GNL1

7.57e-04102167826760575
Pubmed

Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex.

AFDN ITGA3

8.24e-042267226733533
Pubmed

PTENα and PTENβ promote carcinogenesis through WDR5 and H3K4 trimethylation.

CAD RPS5 CHD4 SSRP1

8.31e-0421767431685992
Pubmed

Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium.

KLF5 PPARG

9.82e-042467221803035
Pubmed

Importin 8 is a gene silencing factor that targets argonaute proteins to distinct mRNAs.

RPS5 SPTBN1 AGK

9.95e-0410167319167051
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

CAD CEP78 SGPL1 RPS5 CHD4 SSRP1

1.06e-0360167633658012
Pubmed

Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.

APPBP2 CAD SPTBN1 SSRP1 TWF1

1.07e-0340167525852190
Pubmed

KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.

CAD SPTBN1 FKBP4

1.08e-0310467336055981
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

RPS5 CHD5 SPTBN1 CHD3 CHD4 SSRP1

1.10e-0360567628977666
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PACS1 SGPL1 FA2H TTLL4 SPTBN1 TUT7 ENTPD6 CHD3

1.11e-03108467811544199
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

CAD RPS5 SPTBN1 TUT7

1.12e-0323567430258100
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

APPBP2 TTC28 HIPK1 HERC3 MAPKBP1

1.14e-0340767512693553
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

CAD CHD4 SSRP1

1.14e-0310667319394292
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

RPS5 SPTBN1 CHD3 CHD4 SSRP1 FKBP4 TWF1

1.21e-0384767735235311
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SGPL1 RPS5 AGK CHD3 CHD4 HACD2 SSRP1

1.21e-0384767735850772
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

CEP78 SPTBN1 TUT7 AGK CHD3 CHD4 SNX33 SSRP1 GNL1

1.22e-03137167936244648
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

CAD RPS5 SPTBN1 CHD4 SSRP1 TWF1

1.31e-0362667633644029
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

ERRFI1 SSRP1 DNAH8 DNAH7 BBS10

1.31e-0342067528065597
Pubmed

ACAA2 is a ligand-dependent coactivator for thyroid hormone receptor β1.

FA2H CHD5 PRR5

1.38e-0311367334474245
Pubmed

Large-scale cDNA transfection screening for genes related to cancer development and progression.

PRR5 ABHD16A FAM43A

1.41e-0311467315498874
Pubmed

RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.

CAD CHD4

1.44e-032967236800290
GeneFamilyPHD finger proteins|NuRD complex

CHD5 CHD3 CHD4

2.01e-06123931305
GeneFamilyDyneins, axonemal

DNAH8 DNAH7

6.04e-0417392536
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP6 PARP8

6.04e-0417392684
GeneFamilyPHD finger proteins

CHD5 CHD3 CHD4

9.58e-049039388
CoexpressionDUTERTRE_ESTRADIOL_RESPONSE_24HR_DN

SOCS2 PACS1 KLF5 PARP8 ERRFI1 PRR5 HERC3 PPARG GULP1

5.32e-06504679M2157
CoexpressionGSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_2H_UP

SOCS2 FNDC3B TTLL4 ERRFI1 AFDN FKBP4

1.24e-05200676M8733
ToppCellfacs-Bladder-nan-18m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 FA2H ENPP5 ITGA3 PPARG

4.49e-0719267618546b4d5e39aafa97186104d47cfda02eb5f4b5
ToppCellASK452-Epithelial-Type_1|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

FMO2 VSIG2 KLF5 ARHGAP44 ERRFI1 ITGA3

5.22e-07197676dc0a6dca4af6b216357b06f67203274f8b2a8bb0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF5 SPTBN1 DHRS9 ERRFI1 AFDN GULP1

5.70e-07200676f386a86b127433cbac306950443355bd723080ff
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM232 KLF5 SPTBN1 DHRS9 AFDN GULP1

5.70e-072006761c02a7f4047d1d2208cc522c6bb4a4989d7845bb
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

KLF5 SPTBN1 DHRS9 ERRFI1 AFDN GULP1

5.70e-07200676b75154417c215b8853186bff46d624ebd387ac4f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM232 KLF5 SPTBN1 DHRS9 AFDN GULP1

5.70e-0720067603051d2190244208905e1611019d4b8fd200bae0
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FMO2 LOXHD1 VSIG2 ARHGAP44 ITGA3

7.45e-061796751603117b52623663458a977c94bf7f9f6c1114b8
ToppCellAT1_cells-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

FMO2 VSIG2 SPTBN1 ARHGAP44 ITGA3

7.66e-061806752d52cb5f77dde0e3dccac1333d4ec67ec680fcb2
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 SGPL1 ENTPD6 ENPP5 HACD2

8.52e-06184675382b1e90b3f437af596750669c0465a169d97095
ToppCellControl-Epithelial-ATI|World / Disease state, Lineage and Cell class

FMO2 VSIG2 SPTBN1 ARHGAP44 ITGA3

8.75e-061856750563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

FMO2 VSIG2 SPTBN1 ARHGAP44 ITGA3

9.21e-06187675fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

FMO2 SPTBN1 ARHGAP44 AFDN ITGA3

9.21e-0618767577f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLF5 ARHGAP44 ERRFI1 AFDN ITGA3

9.45e-06188675eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCelldroplet-Limb_Muscle-nan-3m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENTPD5 PRICKLE2 ITGA3 PPARG ZZEF1

9.70e-0618967516a4c92dd7a0d60f3691bd3130a091a9a54730f1
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

FMO2 SPTBN1 ARHGAP44 AFDN ITGA3

9.70e-061896755a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FMO2 SPTBN1 ARHGAP44 AFDN ITGA3

9.95e-0619067530b50d183d7649146eb1e79b47ba897355f1998a
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

FMO2 VSIG2 KLF5 SPTBN1 ITGA3

1.02e-0519167566875b2ec2c510489407f3e433a90cdf74a15094
ToppCellfacs-Bladder-nan-18m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 FA2H ENPP5 PPARG

1.02e-05191675b842647caf05d39f602de83c647d5c224715d19f
ToppCelldroplet-Bladder-nan-24m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 SGPL1 KLF5 ENPP5 HACD2

1.07e-051936755b30bbb354c69f684a1c8d2c68e9b3424d759e8d
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

VSIG2 KLF5 DHRS9 AFDN GULP1

1.07e-05193675518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

VSIG2 KLF5 DHRS9 AFDN GULP1

1.07e-051936754e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 SGPL1 KLF5 ENPP5 HACD2

1.13e-05195675d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCellAT2_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

KLF5 RPS5 SPTBN1 ERRFI1 ITGA3

1.19e-05197675c36513e893488c4299119d4fba6ef0fd72610ee6
ToppCellASK440-Epithelial-Type_1|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

FMO2 VSIG2 KLF5 SPTBN1 ITGA3

1.19e-051976751eda2c2504451a3d626dda5c2b2b12eeaa6bca54
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KLF5 ARHGAP44 ERRFI1 ITGA3 GULP1

1.21e-05198675691a2f1779225e5519155460eeb6a2aac5f67a92
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KLF5 ARHGAP44 ERRFI1 ITGA3 GULP1

1.21e-05198675aed0476248e9637897eefb1623ec4035f2dacd82
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

KLF5 ARHGAP44 ERRFI1 ITGA3 GULP1

1.21e-05198675e115eea04012e9e492e923ed080e1723c38d14fd
ToppCellBAL-Severe-Epithelial-Epithelial-AT1/AT2-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KLF5 ARHGAP44 ERRFI1 ITGA3 GULP1

1.21e-0519867533d1e0b6f57663544bee0ffdde83a65da764d44c
ToppCellSevere_COVID-19-Epithelial-AT1/AT2|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

KLF5 ARHGAP44 ERRFI1 ITGA3 GULP1

1.21e-0519867543e33d28d9de5033bd00d39be953542a225236ed
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VSIG2 KLF5 DHRS9 ERRFI1 AFDN

1.24e-051996755a1557fe35aa48080d4967e8724bf27f9585a5fb
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

VSIG2 KLF5 DHRS9 ERRFI1 AFDN

1.24e-051996750a657475b92aa3a713da62da364525249fdc3886
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 VSIG2 KLF5 ERRFI1 ITGA3

1.24e-05199675c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCellPSB-critical-LOC-Epithelial|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KLF5 SPTBN1 DHRS9 AFDN GULP1

1.24e-0519967558dcb0eedafa8629585dc99e53147e2287f49689
ToppCellBiopsy_Other_PF-Epithelial-AT1|Biopsy_Other_PF / Sample group, Lineage and Cell type

FMO2 VSIG2 KLF5 ERRFI1 ITGA3

1.27e-05200675b746dcc94814bcbca63c71e6451a9c5f084bcfaf
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c4-DNAJB1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

VSIG2 DHRS9 ERRFI1 BBS10

7.33e-05148674e73860f6b8021482f82b83ccd2b7e1dfd7d9e80b
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2-Th.Adora2a-Th_(Striatum,_Th+_SPN)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LOXHD1 CPB1 LRIT3

8.27e-0556673e6b2f6ff08887ae8335c44d7fff118c371768809
ToppCellGlobus_pallidus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a-Excitatory_Neuron.Gad1Gad2-Th.Adora2a-Th_(Striatum,_Th+_SPN)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

LOXHD1 CPB1 LRIT3

8.27e-05566737a1f39e2ebe70d757847e4fb02c39313b1ea5a2d
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

TMEM232 DHRS9 DNAH7 IQUB

1.17e-0416767426cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

CAD NTAN1 KLF5 HIPK1

1.20e-041686748459d0a1bf6d4b5c83001097331f8b78fceb9305
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM232 AGK ENPP5 IQUB

1.20e-041686749a8709d34865cfa668d8f3335dc34fc86fc32482
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 VSIG2 KLF5 ITGA3

1.25e-041706744cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell356C-Epithelial_cells-Epithelial-E_(AT2)|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 VSIG2 KLF5 ITGA3

1.25e-0417067436c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

VSIG2 ARHGAP44 CHD3 ITGA3

1.31e-041726740be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellTCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

FMO2 TMEM232 SRD5A2 DNAH7

1.31e-041726746b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

SPTBN1 ARHGAP44 AFDN ITGA3

1.37e-04174674548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VSIG2 KLF5 FA2H PPARG

1.40e-041756748727252bcbc70bfa2ff72e7421df9cfe6fd4eed7
ToppCell3'-GW_trimst-1-LargeIntestine-Epithelial-Tuft-related|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VSIG2 KLF5 FA2H PPARG

1.40e-04175674c083abe368e5c0dc2b0f27f375c9271a2d7ff64f
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 SPTBN1 AFDN FAM43A

1.46e-04177674ca5a30b3e7bcfdd8de01ceaf7449735b5cd503af
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 SPTBN1 AFDN FAM43A

1.46e-04177674f471f7747d6e8db7546899019af9508f48a14f89
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 SPTBN1 AFDN FAM43A

1.46e-04177674cd0684b876c2a7d5fe7e2773e8e25bb61ecbc795
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LOXHD1 SPTBN1 PRICKLE2 GULP1

1.46e-04177674b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TTC28 PARP8 ARHGAP44

1.49e-04178674d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TTC28 PARP8 ARHGAP44

1.49e-04178674b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TTC28 PARP8 ARHGAP44

1.49e-041786740f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCellfacs-Bladder-nan-24m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 RPS5 FA2H

1.53e-04179674fc9f44fb81da0d381a5141a95a005e66a0be28cc
ToppCellfacs-Bladder-nan-24m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 RPS5 FA2H

1.53e-041796749152d92bb96e65d43de54e933494f0d08ae02c4f
ToppCellCOVID-19-Endothelial_cells-Capillary_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

SPTBN1 PRICKLE2 HERC3 ITGA3

1.59e-04181674c5f9c92af1384d9089c65afdf41c6feb8345a3ae
ToppCelldroplet-Lung-LUNG-1m-Epithelial-type_II_pneumocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 ARHGAP44 ERRFI1

1.63e-04182674c1e0be27064e14043b78ae501b02d4e9542267a3
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VSIG2 DHRS9 ENTPD5 LRIT3

1.63e-0418267494e70746e35a3062015d4b83ee545f4f84f47420
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOCS2 SPTBN1 AFDN CHD3

1.63e-04182674c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SOCS2 SPTBN1 AFDN CHD3

1.63e-041826744cb182ef39be2044a6ad7266f332d4177591e550
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Alveolar_Epithelial_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 ARHGAP44 ERRFI1

1.63e-041826743c9b4869d357884ae4bcd22a9872faf83a5cfc6d
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

SPTBN1 ARHGAP44 ERRFI1 ITGA3

1.66e-04183674dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

VSIG2 KLF5 ARHGAP44 ERRFI1

1.66e-0418367423e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCellfacs-Bladder-nan-24m-Epithelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 RPS5 FA2H

1.66e-04183674268fc48ffd88e19c9dcd1af32b635256fc915742
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial-AT2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

VSIG2 KLF5 ARHGAP44 ERRFI1

1.66e-041836740a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPTBN1 ARHGAP44 AFDN ITGA3

1.70e-0418467457c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellCiliated_cells-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

FMO2 TMEM232 SRD5A2 DNAH7

1.70e-0418467407c5a9633ccdcd18771e3230d6198a55c400afa6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

FMO2 SPTBN1 ARHGAP44 AFDN

1.70e-04184674561592edc3083fad41b91811151b442207c65dd9
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPTBN1 ARHGAP44 AFDN ITGA3

1.70e-04184674d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPTBN1 ARHGAP44 AFDN ITGA3

1.73e-041856741c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SOCS2 FNDC3B CEP78 SGPL1

1.73e-041856747925519b855f76444a0b57382ce35d89457b0b14
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

TULP4 CHD3 SNX33 PPARG

1.77e-04186674701eea0016d69f0f9d29b613948f91239096e6c7
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 RPS5 FA2H

1.77e-041866748589d55f7f778442bf31cd4eb1fdaa632f1b7ab0
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 FA2H ENTPD5 PPARG

1.81e-04187674dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
ToppCellfacs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF5 ERRFI1 ITGA3 MAPKBP1

1.81e-041876749c1013720c248ef201d010806b6e7ad24205e8ee
ToppCelldroplet-Marrow-BM-1m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF5 ENTPD5 HACD2 SSRP1

1.81e-041876746be99f71532b7d679d1287ea1bb08245d9538db7
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

SPTBN1 PRICKLE2 HERC3 ITGA3

1.84e-0418867488b3415e33db81726dd29c1f50c886e057af50a0
ToppCelldroplet-Marrow-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF5 ENTPD5 HACD2 SSRP1

1.84e-041886741526e271411e381eae7a342003002276f83f47a3
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

SOCS2 TTC28 ARHGAP44 PLPPR1

1.84e-04188674ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellfacs-Skin-Telogen-3m-Epithelial-Basal_IFE|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF5 ERRFI1 ITGA3 MAPKBP1

1.84e-041886748cc927b4c51d982fdafa04dc7393617ad9bb220e
ToppCellSevere_COVID-19-Epithelial-undefined_Epi|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

VSIG2 KLF5 FA2H DHRS9

1.88e-041896748cbd35320c7e7ff013ef0c0f13f8d875db1c53cd
ToppCelldroplet-Bladder|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 SGPL1 FA2H PPARG

1.92e-04190674170484f7a6f0a0d0792bbe1bb04abad060b7188e
ToppCelldroplet-Bladder-nan-24m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 RPS5 ENTPD5

1.96e-0419167447066fda0eb1576023c1906584713d1b03e2303c
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPTBN1 AFDN PPARG FAM43A

1.96e-041916745020fe6c3452e7fab57847f5043d28ebbc5aa381
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FMO2 VSIG2 CXorf65

1.97e-04756733167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FMO2 VSIG2 CXorf65

1.97e-047567370c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

FMO2 VSIG2 CXorf65

1.97e-047567326d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCellCOPD-Epithelial|COPD / Disease state, Lineage and Cell class

TMEM232 KLF5 PRICKLE2 ITGA3

2.00e-041926740644fad5df18f0021f6f49cca996d8cf47f972ff
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

VSIG2 KLF5 ERRFI1 PLPPR1

2.00e-0419267439804d9ddc67c1b41887752df2503389eae44a1a
ToppCell(5)_Epi_upper|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

FMO2 VSIG2 DHRS9 AFDN

2.00e-041926740c8f73cfd24531a040544df39f28626433aaa651
ToppCell(5)_Epithelial_cells-(5)_Epi_upper|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

FMO2 VSIG2 DHRS9 AFDN

2.00e-0419267469b6b3ceaad6432c46d1bc2a00b8389069a8876e
ToppCellILEUM-inflamed-(1)_T_cell-(1)_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

KLF5 RPS5 PARP8 PRR5

2.00e-041926749a2560921b8c0997e1788053004f099439e8f071
ToppCellNS-critical-d_0-4-Epithelial-Basal|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KLF5 FA2H ARHGAP44 FN3KRP

2.04e-041936741affb4c2e21712bde0d36ab736411fe36642cc6d
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 SGPL1 KLF5 FA2H

2.04e-04193674268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC3B AFDN ITGA3 DNAH7

2.04e-04193674f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCelldroplet-Bladder-nan-24m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 KLF5 RPS5 ENTPD5

2.04e-0419367466dd5ea1f9ea4b6160a0b79b068a421754689312
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VSIG2 KLF5 ARHGAP44 ERRFI1

2.04e-041936744a1b4a2faf741ffba5c84218af4df6a8b2a9f4de
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VSIG2 SGPL1 KLF5 HACD2

2.04e-04193674ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCellfacs-Lung-24m-Epithelial-alveolar_epithelial-type_II_pneumocyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VSIG2 KLF5 ARHGAP44 ERRFI1

2.04e-0419367468adc680deb2f1a29d3cca19c13b9f6271dd4d60
Diseaseplasminogen activator inhibitor 1 measurement

TMEM232 PARP8 PPARG

2.44e-0454663EFO_0004792
DiseaseProstate cancer, familial

TTC28 SRD5A2 CHD3

5.04e-0469663C2931456
Diseaselevel of Phosphatidylcholine (15:0_18:2) in blood serum

NTAN1 BUD13

7.37e-0418662OBA_2045065
DiseasePseudopelade

SRD5A2 PPARG

8.22e-0419662C0086873
DiseaseColorectal Carcinoma

CAD KLF5 PARP8 CHD5 PPARG DNAH8 IQUB

9.66e-04702667C0009402
DiseaseObesity

PACS1 ENTPD6 PPARG BBS10

1.16e-03205664C0028754
DiseaseHypermetropia

FMO2 TULP4 PRICKLE2

1.61e-03103663HP_0000540
Diseaseeosinophil count

TMEM232 FA2H PARP8 SPTBN1 ENTPD6 BUD13 PPARG PLPPR1 DNAH7 FAM43A

1.65e-0314886610EFO_0004842
Diseasepathological myopia

PARP8 SPTBN1 CHD4

2.00e-03111663EFO_0004207

Protein segments in the cluster

PeptideGeneStartEntry
LSSPKYSLYEVHVSG

AFDN

86

P55196
GASHLSFPKNSKYEY

BUD13

306

Q9BRD0
YLGPLKIKAAHFFST

AGK

226

Q53H12
KPNHAEYASKYLTAR

CXorf65

56

A6NEN9
SLYKEGHSKGPYLVS

CHD5

741

Q8TDI0
GYLSLSKVVPFSHYA

ABHD16A

86

O95870
GSKHPKYSDTLLDYG

APPBP2

281

Q92624
SGRKHSLGKEYYAPA

CEP78

366

Q5JTW2
KSKTGKYSFPHTYIR

BBS10

646

Q8TAM1
YGLKNHKLLSKSYSS

PARP8

421

Q8N3A8
KLYTHSYLGFGLKAA

ENTPD5

236

O75356
SSSFYSAYHGKIPKA

FN3KRP

256

Q9HA64
KYYTHSKTLPATQGQ

HIPK1

41

Q86Z02
YKGDYSATHPTVKLF

HERC3

951

Q15034
LKIKGIHPYHSLSYT

KIAA1109

2251

Q2LD37
IPYYVSVTTGKHKDA

LOXHD1

1421

Q8IVV2
LGKVYIYHSSSKGLL

ITGA3

396

P26006
KTYPNHYTLVTGLFA

ENPP5

71

Q9UJA9
HVTPKSYLSFINGYK

DNAH8

3036

Q96JB1
LGKIHGAYSSEKLSY

GNL1

156

P36915
HNSAVTVLYSKYGGK

LRIT3

511

Q3SXY7
SHPVAKYLGSVDSKY

PACS1

666

Q6VY07
ASLAGAPKYIEHFSK

PDK2

11

Q15119
LTLSLGYGYHPNKSS

PKD1L2

1206

Q7Z442
SDELLHKYSSYGLPK

PRICKLE2

806

Q7Z3G6
HKYSSYGLPKSSTLG

PRICKLE2

811

Q7Z3G6
GSPHKGSYLYSLKAH

FA2H

321

Q7L5A8
YSLYKEGHTKGPFLV

CHD3

776

Q12873
EYTFTHLKPGTLYKL

FNDC3B

631

Q53EP0
AKGSYHSLYYSIEKP

HACD2

66

Q6Y1H2
SKHFIPYNAKFLGST

GULP1

21

Q9UBP9
GLYKLEKTFHDSPYA

DNAH7

806

Q8WXX0
SGDHKSYIEYTKTLP

DNAH7

3686

Q8WXX0
SKPKGYAVSLHYSAL

FAM43A

21

Q8N2R8
PKKVGKVYSALYHSS

MAPKBP1

376

O60336
KLVTPGKYFSAAEYH

IQUB

321

Q8NA54
SLYKYIFPAHLDKST

FMO2

351

Q99518
PLGSYHKTIKYASLL

CCDC168

3476

Q8NDH2
HSIVYLKPSYAFGSV

FKBP4

216

Q02790
YSLYKEGHSKGPFLV

CHD4

766

Q14839
ALTSLFPKTHYAAGK

DHRS9

271

Q9BPW9
KELASLHGTKYTYGP

CPB1

336

P15086
VHYGFASVIYLKPKS

OR10H1

251

Q9Y4A9
ASYTKLQLHGAAYGK

PARP6

491

Q2NL67
AKYLPHSAGRYAAKR

RPS5

46

P46782
THETFKALKPGLSAY

ENTPD6

131

O75354
GYILKPHFLRESKSY

PLCZ1

456

Q86YW0
KVVSPYLGTYGLHSS

PRR5

206

P85299
ALAKHLYDSYIKSFP

PPARG

241

P37231
GTVHLYLTKPLYTSA

SOCS2

146

O14508
IKSYISYKLTPTHAA

SNX33

246

Q8WV41
PAHTLFSGNKALLYK

NTAN1

281

Q96AB6
FPSKHAALSIYSALY

PLPPR1

196

Q8TBJ4
YSADPHAIAGALKSY

ARHGAP44

316

Q17R89
PIIENGKKVSSTHYY

ERRFI1

381

Q9UJM3
SISADTHKYGYAPKG

SGPL1

346

O95470
THKYGYAPKGSSLVL

SGPL1

351

O95470
HGKTFDYKIPYTTVL

SSRP1

226

Q08945
FYKDAKTAASGIPYH

SPTBN1

2236

Q01082
KKGDFSLYPTSVHYQ

TULP4

866

Q9NRJ4
ALSFSGASYHKYPNI

TMEM232

201

C9JQI7
GKAFSLPSTFTYHKR

ZNF716

386

A6NP11
YVAKPSGYGKHTESL

SRD5A2

26

P31213
SALASKATGYPLAYV

CAD

691

P27708
FKLKYPSSPYSAHIS

TTC28

2286

Q96AY4
AKKYSYGHLPTHSIT

ZZEF1

1861

O43149
YKYFALPHKITKSSL

TUT7

626

Q5VYS8
YLHKPYLISGSKFDL

TTLL4

751

Q14679
YFTNGHLYPTGSKSK

VSIG2

76

Q96IQ7
LHGYKKYLLSQSSPA

TWF1

131

Q12792
DYPGCTKVYTKSSHL

KLF5

376

Q13887