Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchromo shadow domain binding

ATRX NIPBL

7.41e-056452GO:0070087
GeneOntologyMolecularFunctionribosome binding

LARP1 NOMO2 NOMO3 NOMO1

1.53e-04120454GO:0043022
GeneOntologyBiologicalProcessmulti-pass transmembrane protein insertion into ER membrane

NOMO2 NOMO3 NOMO1

8.08e-079453GO:0160063
GeneOntologyBiologicalProcessmaintenance of mitotic sister chromatid cohesion

ATRX SLF2 NIPBL

2.73e-0613453GO:0034088
GeneOntologyBiologicalProcessmaintenance of sister chromatid cohesion

ATRX SLF2 NIPBL

3.47e-0614453GO:0034086
GeneOntologyBiologicalProcessprotein insertion into ER membrane

NOMO2 NOMO3 NOMO1

4.18e-0531453GO:0045048
GeneOntologyBiologicalProcessmitotic sister chromatid cohesion

ATRX SLF2 NIPBL

6.59e-0536453GO:0007064
GeneOntologyBiologicalProcessplacenta development

E2F7 MME CUL7 RXRB ASH1L

6.77e-05197455GO:0001890
GeneOntologyBiologicalProcessuterus morphogenesis

NIPBL ASH1L

6.94e-056452GO:0061038
GeneOntologyBiologicalProcessregulation of cell cycle process

MKI67 E2F7 PUM2 SIN3A CUL7 ATRX SLF2 PHF10 USP19

7.32e-05845459GO:0010564
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

NOMO3 NOMO1

9.71e-057452GO:1900108
GeneOntologyBiologicalProcessdevelopmental growth

ANKRD26 PUM2 MACF1 XIRP1 SIN3A COMP ATRX NIPBL RXRB

1.30e-04911459GO:0048589
GeneOntologyBiologicalProcessregulation of nodal signaling pathway

NOMO3 NOMO1

1.66e-049452GO:1900107
GeneOntologyBiologicalProcessregulation of maintenance of mitotic sister chromatid cohesion

ATRX SLF2

1.66e-049452GO:0034182
GeneOntologyBiologicalProcessprotein insertion into membrane

NOMO2 NOMO3 NOMO1

1.77e-0450453GO:0051205
GeneOntologyBiologicalProcesscell cycle process

MKI67 E2F7 PUM2 SIN3A CUL7 ATRX SLF2 PHF10 NIPBL PPP1R12A USP19

2.07e-0414414511GO:0022402
GeneOntologyBiologicalProcessdetermination of left/right asymmetry in lateral mesoderm

NOMO3 NOMO1

2.07e-0410452GO:0003140
GeneOntologyBiologicalProcessregulation of maintenance of sister chromatid cohesion

ATRX SLF2

2.07e-0410452GO:0034091
GeneOntologyBiologicalProcessregulation of cell cycle

MKI67 E2F7 PUM2 SIN3A CUL7 ATRX CDKL2 SLF2 PHF10 USP19

3.04e-0412564510GO:0051726
GeneOntologyBiologicalProcesssister chromatid cohesion

ATRX SLF2 NIPBL

4.22e-0467453GO:0007062
GeneOntologyBiologicalProcesspositive regulation of DNA-templated DNA replication

E2F7 ATRX

4.80e-0415452GO:2000105
GeneOntologyBiologicalProcessprotein localization to organelle

MACF1 SIN3A DNAAF11 ATRX SLF2 NOMO2 NIPBL NOMO3 NOMO1

4.95e-041091459GO:0033365
GeneOntologyBiologicalProcesspositive regulation of cell cycle process

E2F7 SIN3A ATRX SLF2 USP19

5.30e-04307455GO:0090068
GeneOntologyCellularComponentmulti-pass translocon complex

NOMO2 NOMO3 NOMO1

7.76e-079453GO:0160064
GeneOntologyCellularComponentER membrane insertion complex

NOMO2 NOMO3 NOMO1

3.34e-0614453GO:0072379
GeneOntologyCellularComponentchromosomal region

MKI67 SIN3A ATRX SLF2 PHF10 THOC5 PPP1R12A

3.00e-05421457GO:0098687
GeneOntologyCellularComponentcondensed chromosome

MKI67 SIN3A ATRX SLF2 PHF10 PPP1R12A

4.81e-05307456GO:0000793
GeneOntologyCellularComponentchromosome, centromeric region

MKI67 SIN3A ATRX PHF10 PPP1R12A

3.07e-04276455GO:0000775
GeneOntologyCellularComponentcondensed chromosome, centromeric region

SIN3A ATRX PHF10 PPP1R12A

7.81e-04193454GO:0000779
GeneOntologyCellularComponentactin cytoskeleton

ANKRD26 MACF1 XIRP1 ABLIM2 ARHGAP21 PPP1R12A

1.39e-03576456GO:0015629
DomainDUF2012

NOMO2 NOMO3 NOMO1

4.87e-084443PF09430
DomainDUF2012

NOMO2 NOMO3 NOMO1

4.87e-084443IPR019008
DomainCarb-bd-like_fold

NOMO2 NOMO3 NOMO1

6.78e-078443IPR013784
DomainCarboxyPept_regulatory_dom

NOMO2 NOMO3 NOMO1

3.43e-0613443IPR014766
Domain-

NOMO2 NOMO3 NOMO1

3.43e-06134432.60.40.1120
DomainCarboxyPept-like_regulatory

NOMO2 NOMO3 NOMO1

8.11e-0617443IPR008969
DomainCS

DNAAF11 USP19

4.85e-0414442PF04969
DomainCS_dom

DNAAF11 USP19

6.37e-0416442IPR007052
DomainCS

DNAAF11 USP19

6.37e-0416442PS51203
DomainZF_PHD_2

ATRX PHF10 ASH1L

1.45e-0395443PS50016
DomainZF_PHD_1

ATRX PHF10 ASH1L

1.50e-0396443PS01359
DomainZnf_FYVE_PHD

ATRX PHF10 ASH1L

5.00e-03147443IPR011011
DomainARM-type_fold

ARFGEF3 PUM2 CUL7 NIPBL

8.18e-03339444IPR016024
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

MKI67 ANKRD26 LARP1 PUM2 MACF1 UPF3B SIN3A ATRX NIPBL ARHGAP21 PPP1R12A UTP14A

1.67e-09934451233916271
Pubmed

Recurrent NOMO1 Gene Deletion Is a Potential Clinical Marker in Early-Onset Colorectal Cancer and Is Involved in the Regulation of Cell Migration.

NOMO2 NOMO3 NOMO1

2.02e-09345336011023
Pubmed

Silencing of nodal modulator 1 inhibits the differentiation of P19 cells into cardiomyocytes.

NOMO2 NOMO3 NOMO1

2.02e-09345325576386
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ANKRD26 ARFGEF3 E2F7 MACF1 UPF3B CUL7 ATRX SLF2 NOMO2 RBM20

3.32e-09588451038580884
Pubmed

Establishment of a conditional Nomo1 mouse model by CRISPR/Cas9 technology.

NOMO2 NOMO3 NOMO1

8.09e-09445331833031
Pubmed

A locus for autosomal recessive pseudoxanthoma elasticum, with penetrance of vascular symptoms in carriers, maps to chromosome 16p13.1.

NOMO2 NOMO3 NOMO1

8.09e-0944539267806
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NOMO2 NOMO3 NOMO1

1.13e-07845315257293
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NOMO2 NOMO3 NOMO1

1.69e-07945336261522
Pubmed

Human transcription factor protein interaction networks.

MKI67 PSMC3 LARP1 PUM2 WBP11 SIN3A CUL7 ATRX PHF10 NIPBL RBM20 UTP14A

1.80e-071429451235140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ANKRD26 LARP1 MACF1 SCN11A WBP11 POLQ ATRX NIPBL ARHGAP21 PPP1R12A UTP14A ASH1L

1.99e-071442451235575683
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

UPF3B SIN3A CUL7 ATRX NOMO2 ARHGAP21 PPP1R12A NOMO3 CNGB3 NOMO1

1.99e-07910451036736316
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

MKI67 ANKRD26 LARP1 PUM2 MACF1 PHF10 THOC5 PPP1R12A UTP14A

3.17e-0772445936232890
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

NOMO2 NOMO3 NOMO1

3.32e-071145332820719
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

MKI67 ATRX NIPBL UTP14A

4.80e-068645437253089
Pubmed

EGFR, CD10 and proliferation marker Ki67 expression in ameloblastoma: possible role in local recurrence.

MKI67 MME

4.91e-06345222300665
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MKI67 LARP1 PUM2 SIN3A ATRX PHF10 NIPBL USP19

6.04e-0677445815302935
Pubmed

Hepatic lipase maturation: a partial proteome of interacting factors.

NOMO2 NOMO3 NOMO1

8.87e-063145319136429
Pubmed

MUM1 expression dichotomises follicular lymphoma into predominantly, MUM1-negative low-grade and MUM1-positive high-grade subtypes.

MKI67 MME

9.81e-06445217296585
Pubmed

Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity.

MKI67 SIN3A

9.81e-06445227399968
Pubmed

An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.

NOMO2 NOMO3 NOMO1

1.07e-053345330783098
Pubmed

Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly.

MKI67 ATRX

1.63e-05545223892236
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

LARP1 WBP11 SIN3A ATRX ARHGAP21 RBM20 UTP14A

1.89e-0565045738777146
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MKI67 PSMC3 LARP1 MACF1 CUL7 NIPBL UTP14A

1.95e-0565345722586326
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

MKI67 ANKRD26 LARP1 THOC5 PPP1R12A NOMO3 NOMO1

2.29e-0567045722990118
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

LARP1 PUM2 ARHGAP21 PPP1R12A UTP14A

2.76e-0527445534244482
Pubmed

The Histone Methyltransferase Ash1l is Required for Epidermal Homeostasis in Mice.

MKI67 ASH1L

3.42e-05745228374742
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ANKRD26 UBR3 MACF1 CUL7 THOC5 UTP14A

4.01e-0549345615368895
Pubmed

HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.

MKI67 WBP11 ATRX UTP14A

4.10e-0514845432538781
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

MKI67 LARP1 MACF1 UPF3B SIN3A CUL7 UTP14A

5.06e-0575945735915203
Pubmed

The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.

SIN3A ATRX PHF10 ASH1L

5.15e-0515745430186101
Pubmed

ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain.

MKI67 ATRX

5.86e-05945225395668
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MKI67 PSMC3 LARP1 UPF3B ATRX NIPBL USP19 NOMO1 UTP14A

7.41e-05142545930948266
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

LARP1 PUM2 MACF1 WBP11 UPF3B RSRC2 UTP14A

7.43e-0580745722681889
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

MKI67 PSMC3 LARP1 WBP11 UPF3B SIN3A RSRC2 NIPBL

7.58e-05110345834189442
Pubmed

Transmembrane insertases and N-glycosylation critically determine synthesis, trafficking, and activity of the nonselective cation channel TRPC6.

NOMO2 NOMO3 NOMO1

7.61e-056345331266804
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

ATRX PHF10 THOC5 UTP14A

8.21e-0517745426206133
Pubmed

The interactome of the prostate-specific protein Anoctamin 7.

ATRX NIPBL THOC5

8.36e-056545332176628
Pubmed

A protein interaction framework for human mRNA degradation.

UPF3B RSRC2 NOMO2 NOMO3 NOMO1

8.46e-0534745515231747
Pubmed

New tools for studying microglia in the mouse and human CNS.

MKI67 P2RY12

8.94e-051145226884166
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

MKI67 LARP1 WBP11 ARHGAP21 PPP1R12A

1.02e-0436145530344098
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ANKRD26 MACF1 WBP11 ATRX NOMO2 THOC5 NOMO1 PBDC1 UTP14A

1.03e-04148745933957083
Pubmed

Frameshift variants in C10orf71 cause dilated cardiomyopathy in human, mouse, and organoid models.

MKI67 RBM20

1.07e-041245238950288
Pubmed

SPOP targets oncogenic protein ZBTB3 for destruction to suppress endometrial cancer.

RXRB PPP1R12A

1.07e-041245231911863
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

LARP1 SIN3A CUL7 RSRC2 RXRB PPP1R12A UTP14A

1.08e-0485745725609649
Pubmed

Genome-wide association analyses suggest NELL1 influences adverse metabolic response to HCTZ in African Americans.

THSD4 PHF10 PPP1R12A

1.09e-047145323400010
Pubmed

A comprehensive resource of interacting protein regions for refining human transcription factor networks.

SLF2 ARHGAP21 RXRB PPP1R12A

1.10e-0419145420195357
Pubmed

Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.

MACF1 PPP1R12A NOMO3 NOMO1

1.10e-0419145433762435
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

ANKRD26 ARFGEF3 LARP1 MACF1 SLF2 ARHGAP21 PPP1R12A

1.11e-0486145736931259
Pubmed

Arp2/3 inactivation causes intervertebral disc and cartilage degeneration with dysregulated TonEBP-mediated osmoadaptation.

MKI67 COMP

1.27e-041345231961823
Pubmed

The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain.

ATRX NIPBL

1.27e-041345215882967
Pubmed

Microglial control of neuronal development via somatic purinergic junctions.

MKI67 P2RY12

1.47e-041445236130488
Pubmed

Modular patterning of structure and function of the striatum by retinoid receptor signaling.

MKI67 RXRB

1.47e-041445218443282
Pubmed

A protein interaction landscape of breast cancer.

MKI67 MACF1 CUL7 PHF10 ARHGAP21 THOC5

1.60e-0463445634591612
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

MKI67 PSMC3 LARP1 WBP11 PPP1R12A

1.62e-0439945535987950
Pubmed

Perlecan maintains the integrity of cartilage and some basement membranes.

MKI67 COMP

1.70e-041545210579729
Pubmed

Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.

PPP1R12A PBDC1

1.70e-041545230948508
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

MKI67 PSMC3 LARP1 UPF3B RSRC2 THOC5 PPP1R12A UTP14A

1.77e-04124745827684187
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ARFGEF3 PUM2 MACF1 ARHGAP21 USP19

1.78e-0440745512693553
Pubmed

The cell proliferation antigen Ki-67 organises heterochromatin.

MKI67 PHF10 NIPBL THOC5 UTP14A

1.84e-0441045526949251
Pubmed

Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum.

MKI67 MME

1.94e-041645227019864
Pubmed

Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon.

MKI67 COMP

1.94e-041645221939397
Pubmed

Constraint of gene expression by the chromatin remodelling protein CHD4 facilitates lineage specification.

MKI67 SIN3A

1.94e-041645226116663
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

POLQ ATRX SLF2 NIPBL

1.96e-0422245437071664
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

MKI67 PSMC3 MACF1 WBP11 THOC5 PPP1R12A

1.98e-0466045632780723
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

MKI67 LARP1 WBP11 ATRX SLF2 NIPBL UTP14A

2.09e-0495445736373674
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MACF1 WBP11 ATRX SLF2 NOMO2 NIPBL ARHGAP21 ASH1L

2.17e-04128545835914814
Pubmed

Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.

WBP11 NOMO2 NIPBL NOMO3 NOMO1

2.17e-0442545524999758
Pubmed

The sequence and analysis of duplication-rich human chromosome 16.

NOMO2 NOMO3 NOMO1

2.20e-049045315616553
Pubmed

Early Fate Defines Microglia and Non-parenchymal Brain Macrophage Development.

MKI67 P2RY12

2.20e-041745232259484
Pubmed

Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns.

SIN3A ATRX

2.20e-041745214519686
Pubmed

Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca2+ Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response.

MKI67 SIN3A

2.20e-041745232245798
Pubmed

A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development.

MKI67 SIN3A

2.20e-041745227806305
Pubmed

Transcription factors expressed in olfactory bulb local progenitor cells revealed by genome-wide transcriptome profiling.

MKI67 E2F7 SIN3A

2.27e-049145321194568
Pubmed

ATRX proximal protein associations boast roles beyond histone deposition.

ATRX SLF2 UTP14A

2.27e-049145334780483
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

MKI67 PSMC3 LARP1 MACF1 UPF3B NOMO2 NIPBL PPP1R12A

2.31e-04129745833545068
Pubmed

Genome duplications and other features in 12 Mb of DNA sequence from human chromosome 16p and 16q.

NOMO2 NOMO3 NOMO1

2.35e-049245310493829
Pubmed

Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.

SCN11A XIRP1

2.76e-041945224564958
Pubmed

Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.

MKI67 P2RY12

2.76e-041945234428430
Pubmed

Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development.

MKI67 PHF10

2.76e-041945235173232
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

MKI67 LARP1 PUM2 UPF3B RSRC2 THOC5

3.00e-0471345629802200
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

MKI67 PSMC3 LARP1 PUM2 WBP11 UTP14A

3.02e-0471445628302793
Pubmed

Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.

ANKRD26 MACF1

3.06e-042045221689717
Pubmed

Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.

MKI67 ATRX

3.06e-042045219088125
Pubmed

Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.

LARP1 WBP11 ATRX UTP14A

3.13e-0425145428077445
Pubmed

Sin3a regulates epithelial progenitor cell fate during lung development.

MKI67 SIN3A

3.38e-042145228619823
Pubmed

The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart.

MKI67 CUL7

3.72e-042245236877136
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

MKI67 ANKRD26 MACF1 ARHGAP21

3.73e-0426345434702444
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

NOMO2 NOMO3 NOMO1

3.97e-0411045327889896
Pubmed

Failure of extra-embryonic progenitor maintenance in the absence of dosage compensation.

MKI67 ATRX

4.07e-042345222573614
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

PSMC3 LARP1 MACF1 WBP11 UPF3B SIN3A NIPBL UTP14A

4.14e-04141545828515276
Pubmed

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing.

LARP1 UPF3B THOC5

4.40e-0411445331553912
Pubmed

Snf2h-mediated chromatin organization and histone H1 dynamics govern cerebellar morphogenesis and neural maturation.

MKI67 ATRX

4.44e-042445224946904
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

ANKRD26 PSMC3 MACF1 ABLIM2 ARHGAP21

4.45e-0449745523414517
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

MKI67 ANKRD26 ARFGEF3 ARHGAP21 USP19 UTP14A

4.73e-0477745635844135
Pubmed

Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit.

MKI67 E2F7

4.82e-042545228923932
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

LARP1 MACF1 CUL7 UTP14A

4.85e-0428245423667531
Pubmed

DAAM1 and DAAM2 are co-required for myocardial maturation and sarcomere assembly.

MKI67 PPP1R12A

5.22e-042645226526197
Pubmed

The functional interactome landscape of the human histone deacetylase family.

MKI67 SIN3A MME UTP14A

5.32e-0428945423752268
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

MACF1 SIN3A CUL7 RSRC2 PHF10 PPP1R12A ASH1L

5.37e-04111645731753913
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

LARP1 CCDC168 ASH1L

5.50e-0412345326912792
InteractionNAA40 interactions

MKI67 ANKRD26 LARP1 PUM2 MACF1 UPF3B SIN3A ATRX NIPBL ARHGAP21 PPP1R12A UTP14A

1.04e-069784512int:NAA40
InteractionSOX2 interactions

ANKRD26 PSMC3 LARP1 PUM2 MACF1 UPF3B SIN3A CUL7 COMP PHF10 NIPBL ARHGAP21 PPP1R12A UTP14A

1.49e-0614224514int:SOX2
InteractionFUBP1 interactions

MKI67 LARP1 UPF3B SIN3A CUL7 ATRX THOC5

5.13e-06309457int:FUBP1
InteractionCDX2 interactions

ATRX PHF10 THOC5 UTP14A

4.03e-0586454int:CDX2
InteractionPLEC interactions

MACF1 CUL7 RSRC2 ABLIM2 CDKL2 NOMO1 ASH1L

4.32e-05430457int:PLEC
InteractionCIT interactions

MKI67 PSMC3 LARP1 MACF1 UPF3B SIN3A CUL7 NIPBL THOC5 PPP1R12A UTP14A ASH1L

5.68e-0514504512int:CIT
InteractionNUP43 interactions

MKI67 LARP1 CCDC168 CUL7 SLF2 NIPBL PPP1R12A ASH1L

6.40e-05625458int:NUP43
InteractionRBM39 interactions

MKI67 PSMC3 LARP1 PUM2 WBP11 MME CUL7 ATRX THOC5 UTP14A

7.97e-0510424510int:RBM39
InteractionCBX3 interactions

MKI67 MACF1 CUL7 ATRX PHF10 NIPBL PPP1R12A UTP14A

8.06e-05646458int:CBX3
Cytoband3p22.2

SCN11A XIRP1

2.56e-04244523p22.2
Cytoband12p12.3

PLCZ1 WBP11

4.57e-043245212p12.3
Cytoband10p12.1

ANKRD26 ARHGAP21

4.57e-043245210p12.1
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

MKI67 ARFGEF3 WBP11 PPP1R12A

2.17e-04181304694
GeneFamilyX-linked mental retardation|Angiotensin receptors

UPF3B ATRX

3.48e-0353302103
GeneFamilyPHD finger proteins

PHF10 ASH1L

9.74e-039030288
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3

MKI67 UBR3 MACF1 ATRX SLF2 PHF10 NIPBL PPP1R12A

3.07e-06432458Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

MKI67 ANKRD26 UPF3B POLQ ATRX NIPBL ARHGAP21

3.81e-06311457Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

MKI67 ANKRD26 PSMC3 UPF3B POLQ ATRX NIPBL ARHGAP21 UTP14A ASH1L

7.33e-068314510Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

MKI67 THSD4 ANKRD26 PSMC3 MACF1 ATRX PHF10 NIPBL ASH1L

3.14e-05780459Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3

MKI67 ANKRD26 MACF1 ATRX NIPBL ASH1L

3.27e-05291456Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

MKI67 ANKRD26 PSMC3 MACF1 UPF3B RSRC2 ATRX SLF2 PHF10 NIPBL PBDC1

4.18e-0512414511facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

MKI67 ANKRD26 E2F7 PUM2 MACF1 UPF3B RSRC2 ATRX NIPBL ARHGAP21 PBDC1

4.70e-0512574511facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ANKRD26 POLQ ATRX NIPBL UTP14A

5.23e-05192455Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500_k-means-cluster#4

MKI67 ANKRD26 MACF1 ATRX NIPBL

5.23e-05192455Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

ANKRD26 E2F7 WBP11 RSRC2 POLQ NIPBL UTP14A

1.18e-04532457Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

MKI67 ANKRD26 E2F7 PUM2 MACF1 UPF3B RSRC2 ATRX NIPBL ARHGAP21 PBDC1

1.79e-0414594511facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500

MKI67 ANKRD26 PSMC3 MACF1 UPF3B RSRC2 ATRX SLF2 PHF10 NIPBL PBDC1

1.89e-0414684511facebase_RNAseq_e10.5_MandArch_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000

MKI67 UBR3 MACF1 ABLIM2 ATRX SLF2 PHF10 NIPBL PPP1R12A

1.94e-04989459Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

MKI67 UBR3 MACF1 ATRX SLF2 NIPBL PPP1R12A

3.30e-04629457Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_200

ATRX CDKL2 ASH1L

3.39e-0464453gudmap_developingGonad_e16.5_ovary_200_k5
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_500

MKI67 ANKRD26 MACF1 MME ATRX NIPBL

5.68e-04492456Facebase_RNAseq_e10.5_Lateral Nasal Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#5

MKI67 ANKRD26 MACF1 SLF2

6.42e-04186454Facebase_RNAseq_e10.5_Mandibular Arch_500_K5
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 RSRC2 ATRX NIPBL PPP1R12A ASH1L

4.21e-08194456e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell(24)_B_cell_cycling|World / shred on Cell_type and subtype

MKI67 THSD4 E2F7 POLQ ATRX P2RY12

5.35e-08202456a7c9b6b173701348ba35fbb975e0bdd3c1f1d5fe
ToppCell(2)_B_cell-(24)_B_cell_cycling|(2)_B_cell / shred on Cell_type and subtype

MKI67 THSD4 E2F7 POLQ ATRX

1.70e-06199455d5a9a8a71c4de8cbcef947943f60838731bc640b
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MACF1 RSRC2 ATRX NIPBL ASH1L

1.75e-0620045512f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellDividing_Macrophages-Donor_01|World / lung cells shred on cell class, cell subclass, sample id

MKI67 E2F7 POLQ ATRX

1.67e-05152454e39cfc346b35235546b303e7d73e4d9d7120a5fb
ToppCellDividing_Macrophages-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MKI67 POLQ ATRX P2RY12

2.37e-05166454c503036f3c19ef186e1e62c9643c49dea3827f51
ToppCellTCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2|TCGA-Bile_Duct / Sample_Type by Project: Shred V9

THSD4 DNAAF11 COMP ABLIM2

2.48e-05168454c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ P2RY12

2.72e-05172454ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

SERTAD4 MKI67 ARFGEF3 CDKL2

2.91e-05175454fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

SERTAD4 MKI67 ARFGEF3 CDKL2

2.91e-0517545436c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 ATRX ARHGAP21 RBM20

2.97e-05176454749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 SCN11A POLQ

3.04e-05177454f925a15d2162d166a5b60edac3517c6b2d6cfbea
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MACF1 ATRX SLF2 NIPBL

3.54e-051844541154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MACF1 POLQ NOMO2 ASH1L

3.69e-051864548571956890fc9894d766ba294a28e376b4aba428
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ANKRD26 ABLIM2 CDKL2 PHF10

3.77e-05187454c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSRC2 ATRX NIPBL ASH1L

3.85e-05188454d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MKI67 E2F7 MME POLQ

4.26e-05193454e45ce9cf8421512b57f157c24b64793b47b4ba4b
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 MKI67 ATRX NIPBL

4.35e-051944548ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell(7)_Epithelial_cells-(7)_Epithelial-J_(AT1-AT2_progenitors)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MKI67 E2F7 POLQ ATRX

4.35e-051944544d6ae2b25db11a4ae6dadee83be5c8c05b1225c3
ToppCell(4)_B_Hypermutation|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MKI67 MME POLQ ATRX

4.44e-0519545454d2acaff6be6b5604591bdbd7d769ac3e74f223
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MKI67 E2F7 POLQ P2RY12

4.62e-051974540a404b4494a2246d5a92299235056f0fda4d2b48
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MKI67 E2F7 MME POLQ

4.62e-05197454d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

ANKRD26 UPF3B RSRC2 ATRX

4.62e-051974540fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / Treatment groups by lineage, cell group, cell type

MKI67 E2F7 MME POLQ

4.62e-05197454038fd92750257d43d5e980fd06d77742b543f11a
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MACF1 ATRX PPP1R12A ASH1L

4.71e-051984544c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellcritical-Epithelial-FOXN4+|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SERTAD4 E2F7 PSMC3 PHF10

4.71e-051984546b160b3d6a2c1b1641c2c7dcec1a7ef38411fec9
ToppCellCaecum-B_cell-B_cell_cycling|Caecum / Region, Cell class and subclass

MKI67 THSD4 E2F7 POLQ

4.71e-0519845461294fe99a5641ad359796022c3d038470076b3c
ToppCell(3)_DC_Monocyte_Dividing|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

MKI67 E2F7 POLQ ATRX

4.71e-05198454e2b89f6d7c0007ccab62495cd543fe0e5513a9a4
ToppCellCaecum-(2)_B_cell-(24)_B_cell_cycling|Caecum / shred on region, Cell_type, and subtype

MKI67 THSD4 E2F7 POLQ

4.71e-05198454568d47770cd20c6569ca84ea1eafde367642d68b
ToppCell(1)_T_cell_dividing|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MKI67 E2F7 POLQ ATRX

4.71e-05198454dac3a16e3a070a37f4d0ea37633c23fdc8a9c70a
ToppCell(0)_NK_dividing|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MKI67 E2F7 POLQ ATRX

4.71e-05198454c5336d9b802393d6fd6f8446ea4bb6befeb97bfd
ToppCellT_cells-GZMK+GZMB+_T_cells|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MKI67 E2F7 PSMC3 POLQ

4.71e-05198454085ba270f9defbf5ef45108c6d870e1d7c428479
ToppCell(1)_T_cells-(1)_T_cell_dividing|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MKI67 E2F7 POLQ ATRX

4.80e-0519945433afdd1b1b951b360ababf440bc556fd9e1c1db2
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MACF1 ATRX NIPBL ASH1L

4.89e-05200454dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell(18)_cycling_gd_T|World / shred on Cell_type and subtype

MKI67 E2F7 POLQ ATRX

5.19e-052034547d58929058c4769226a29febee1fd8ba64bc9f1a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-Unfolded_protein_responsible_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

ABLIM2 NOMO3 UTP14A

1.45e-04101453ae650e96b93a0d2f0a19ffaf37f21f02fb20651d
ToppCellControl-Lymphoid_T/NK-NK_activated|Control / Disease group, lineage and cell class

THSD4 MACF1 PLCZ1

2.36e-04119453a258d91ac90d4174b6f203d7f96ba6e57c6003e7
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

THSD4 CCDC168 RBM20

2.42e-041204533b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

THSD4 MACF1 ASH1L

2.48e-0412145319333a660800b583fa27b495c1f7828e6636a257
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

2.79e-041264538ae631694bbba40f64e55e2be8162d7a40eeadc5
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-immature_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARFGEF3 COMP PRODH

3.20e-041324539936078c328b1e1d59f9dfdd69d36926a0cdaf0d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

3.20e-04132453f1b448efccbf87caa86d1a794c43a230a4b0758e
ToppCellLA-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

E2F7 PLCZ1 XIRP1

3.72e-041394539e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCellLA-15._Ventricular_Cardiomyocyte_III|LA / Chamber and Cluster_Paper

PLCZ1 XIRP1 RBM20

4.38e-041474538970eb6b82589f39439c61a57d999661ec8342de
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

4.47e-0414845318cfecd6ae20edb74f5d44ba759909df356acf3a
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

UBR3 COMP USP19

4.83e-041524530652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

5.12e-04155453969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLF2 NOMO1 PBDC1

5.21e-041564538790b4b400695571fcf1ccb24c658b5e90854ff7
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

5.21e-04156453b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

5.31e-041574531ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC168 MME ABLIM2

5.51e-04159453fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC168 MME ABLIM2

5.51e-04159453aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC168 MME ABLIM2

5.51e-041594538bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MME DNAAF11 P2RY12

5.61e-0416045370f3637dd0bcfcef421aa114f946fff0048f192e
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A COMP ABLIM2

5.72e-04161453133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A COMP ABLIM2

5.72e-04161453cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A COMP ABLIM2

5.72e-041614539466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN11A COMP ABLIM2

5.82e-0416245396c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MKI67 E2F7 POLQ

5.92e-04163453466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MKI67 E2F7 POLQ

5.92e-041634535285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

5.92e-041634533f434015c0cbefb31eeda133c34f75384c5f7e22
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MKI67 E2F7 POLQ

6.03e-041644534ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.14e-04165453eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.25e-041664532642544070564debe2deb2938d2c33997bf5ef02
ToppCell343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2|343B / Donor, Lineage, Cell class and subclass (all cells)

E2F7 MME POLQ

6.36e-041674537efa0081e79f22b219eac64ffcaedb2179cde299
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.36e-04167453bc132b51dec4e8f1cd2b2cd89f83641976e09292
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.47e-04168453d35944fd9fea9934ce1e76b2b35d48e2300cca61
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 CCDC168 POLQ

6.47e-04168453a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.58e-04169453121768fc51fc3441ec725346a1bbe29e21d05971
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.58e-04169453b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.58e-041694530bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PLCZ1 MME RBM20

6.58e-04169453716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MKI67 E2F7 POLQ

6.58e-04169453e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 POLQ P2RY12

6.58e-0416945354b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.69e-0417045321bfe070e63722672176052b386167ea4c3dc4e5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

6.81e-04171453c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

MKI67 E2F7 POLQ

6.81e-041714534ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MKI67 POLQ CDKL2

6.81e-041714530eea035fde32cc2a75a0d4227911edb5d54ed47e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 E2F7 POLQ

6.92e-0417245335c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

MKI67 E2F7 POLQ

7.04e-041734538a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.04e-04173453a25459b8140b0dbcb73e3b4cc1407b679229f25c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERTAD4 MKI67 E2F7

7.04e-04173453f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 XIRP1 ATRX

7.04e-04173453a5172dee859bf6c2eed46c48bd64dfef0ff9f28f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKI67 XIRP1 ATRX

7.04e-04173453639b5b0b33ce5aa0bc26363c059717012ddc14c0
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

MKI67 E2F7 ARHGAP21

7.04e-0417345367f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.16e-0417445384da9faff088d05233183b425385beb054c92d1b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.16e-041744537b318796728001c17b4043d2b033330c7be40c78
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.16e-04174453c26eac176e9b0cba385630fdc60e0314a4e4caac
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 CCDC168 MME

7.16e-04174453b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.16e-04174453dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell10x5'-blood-Lymphocytic_B_plasma-Plasmablasts|blood / Manually curated celltypes from each tissue

MKI67 E2F7 POLQ

7.28e-041754532e048bf7961c3d86b6e12a1ebae3b3f2359af457
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.28e-04175453876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MKI67 E2F7 POLQ

7.28e-041754536b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.28e-04175453f7d191cde68de8f3457fa62b1df53b6d0dbe5001
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

MKI67 POLQ CDKL2

7.28e-04175453bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellwk_08-11-Mesenchymal-Chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

SERTAD4 THSD4 MME

7.40e-041764531af28b701c4598ce761f85adbd5d79e4918d265a
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MKI67 THSD4 E2F7

7.40e-0417645345c6983ab671b0f306e7390320bd84f848e474cc
ToppCell3'_v3-Lung-Lymphocytic_T_CD4/8-lo-Cycling_T|Lung / Manually curated celltypes from each tissue

MKI67 E2F7 POLQ

7.40e-04176453a40dfd8c4ba16757ff929b2f03a0628acf334de4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MKI67 E2F7 POLQ

7.52e-0417745373ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THSD4 XIRP1 PPP1R12A

7.52e-04177453928118b0ed120ec01c7d753ce523ab609ac24e5f
DiseaseDisease Exacerbation

MKI67 E2F7 CDKL2 RXRB

1.17e-04165454C0235874
DiseaseMalignant neoplasm of breast

MKI67 MACF1 XIRP1 MME NIPBL RXRB THOC5 PRODH

1.95e-041074458C0006142
Diseasedisease free survival

WBP11 CCDC168

3.43e-0418452EFO_0000409
Diseasegamma-glutamyltyrosine measurement

ARHGAP21 ASH1L

7.79e-0427452EFO_0021144
DiseaseMental Retardation, X-Linked

UPF3B ATRX

8.99e-0429452C1136249
Diseasedisease recurrence, unipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

THSD4 E2F7

1.17e-0333452EFO_0003761, EFO_0004952, EFO_0008343, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

PeptideGeneStartEntry
KRNRERNIEAGKDDG

ASH1L

51

Q9NR48
NDDQKDTDQDGRGDA

COMP

356

P49747
SDGEDGSLDQDNRKK

ABLIM2

446

Q6H8Q1
ADGKEKNIGNEQAED

ANKRD26

441

Q9UPS8
NKTKRTDRDQEGADD

RBM20

826

Q5T481
ARRQEREKNGNEEGE

NOMO3

716

P69849
DQNRDLKQGDDDDSK

PUM2

141

Q8TB72
EKNGDEDCQRGGQKK

LARP1

231

Q6PKG0
ARRQEREKNGNEEGE

NOMO2

716

Q5JPE7
EKRADSGEEENTKNG

PBDC1

176

Q9BVG4
QAEGEDGQNLEKRRN

CUL7

1551

Q14999
DDNGRNFNKDGDLVD

MME

591

P08473
RDHDNKQKSDDRGES

NIPBL

816

Q6KC79
ARRQEREKNGNEEGE

NOMO1

716

Q15155
QELDQNKGKGRDVES

MKI67

311

P46013
SLSQDNRKKEQDGGD

P2RY12

321

Q9H244
NRKKEQDGGDPNEET

P2RY12

326

Q9H244
DEDGIRDEKAGINQN

MACF1

4981

Q9UPN3
SDDGEDGRGDEKRKN

PHF10

301

Q8WUB8
GDSSKGEDKQDRNKE

UPF3B

31

Q9BZI7
IDGEKAEKGNRASNA

CDKL2

361

Q92772
KRTGKQNEENPGDEE

ATRX

1301

P46100
GERKKDGDPDSQEQQ

E2F7

251

Q96AV8
GAEGIKEQNQKERDA

ARFGEF3

896

Q5TH69
QDGGDQDERAEKSKL

POLQ

1606

O75417
HQEEDKNEDKRSNAG

DNAAF11

191

Q86X45
EEQGKEDRRGAGQEK

CCDC168

4211

Q8NDH2
DKGRERLNSSENGED

RSRC2

96

Q7L4I2
ETHERKGSDKRGDNQ

PLCZ1

306

Q86YW0
AAERDGSGTNKRDKQ

PRODH

166

O43272
CQRGREQQEKEGKEG

SIN3A

1136

Q96ST3
ENNEKNDRDRGKTNA

SLF2

181

Q8IX21
LNDEKANDDTNRDGG

SERTAD4

281

Q9NUC0
QEERQRGKDKDGDGE

RXRB

276

P28702
REQAAQKKENSEGGE

CNGB3

696

Q9NQW8
QKDRANQESKDGDPR

USP19

26

O94966
EDGANIDLDSQRKGK

PSMC3

106

P17980
SEDEGDNDGERKHQK

UTP14A

31

Q9BVJ6
EDDQDGSQGLGKRKR

UBR3

346

Q6ZT12
NEERNGNLEGEARKT

SCN11A

816

Q9UI33
RDNGERDNNEEKKSG

WBP11

291

Q9Y2W2
AEGKRNRSDTEQEGK

THOC5

21

Q13769
RSQEEGEQKGRNEEK

THSD4

556

Q6ZMP0
GEQKGRNEEKEDLRG

THSD4

561

Q6ZMP0
KDEENGNRGGKQRNR

ARHGAP21

81

Q5T5U3
EQQERQKEEGKSQGD

XIRP1

566

Q702N8
DLKADNQRLKDENGA

PPP1R12A

1006

O14974