Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontyrosine-ester sulfotransferase activity

SULT1A4 SULT1A3

1.79e-0441102GO:0017067
GeneOntologyMolecularFunctionamine sulfotransferase activity

SULT1A4 SULT1A3

1.79e-0441102GO:0047685
GeneOntologyMolecularFunctionflavonol 3-sulfotransferase activity

SULT1A4 SULT1A3

2.97e-0451102GO:0047894
GeneOntologyCellularComponentnuclear body

KLHDC2 AHCTF1 RNF113A NOC3L OBSCN SMC4 E4F1 RUFY1 RFXAP TP53INP2 PPARGC1A PRPF40B GLI2 PKN2 TP53BP1

7.71e-0590311015GO:0016604
GeneOntologyCellularComponentUSH2 complex

PDZD7 ADGRV1

1.64e-0441102GO:1990696
GeneOntologyCellularComponentstereocilia ankle link

PDZD7 ADGRV1

4.06e-0461102GO:0002141
GeneOntologyCellularComponentstereocilia ankle link complex

PDZD7 ADGRV1

4.06e-0461102GO:0002142
GeneOntologyCellularComponentapical dendrite

FLNA CPEB3 PPARGC1A

6.29e-04321103GO:0097440
GeneOntologyCellularComponentstereocilia coupling link

PDZD7 ADGRV1

7.53e-0481102GO:0002139
GeneOntologyCellularComponentcalyx of Held

GIT1 KCNC3 PRKCG

8.92e-04361103GO:0044305
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 KASH5 GUCY2D

1.22e-03401103GO:0005640
GeneOntologyCellularComponentmicrotubule organizing center attachment site

SYNE1 KASH5

1.46e-03111102GO:0034992
GeneOntologyCellularComponentmeiotic nuclear membrane microtubule tethering complex

SYNE1 KASH5

1.46e-03111102GO:0034993
GeneOntologyCellularComponentnuclear membrane protein complex

SYNE1 KASH5

1.46e-03111102GO:0106083
GeneOntologyCellularComponentnuclear membrane microtubule tethering complex

SYNE1 KASH5

1.46e-03111102GO:0106094
DomainFN3

NPHS1 FLNC FN1 KIAA0319L OBSCN IL21R ROBO3

1.26e-041851127SM00060
DomainK_chnl_volt-dep_Kv3

KCNC2 KCNC3

2.12e-0441122IPR003974
DomainFN3_dom

NPHS1 FLNC FN1 KIAA0319L OBSCN IL21R ROBO3

2.67e-042091127IPR003961
DomainACTININ_2

FLNA FLNC SYNE1

3.41e-04231123PS00020
DomainACTININ_1

FLNA FLNC SYNE1

3.41e-04231123PS00019
DomainActinin_actin-bd_CS

FLNA FLNC SYNE1

3.41e-04231123IPR001589
DomainIG_FLMN

FLNA FLNC

1.55e-03101122SM00557
DomainFilamin

FLNA FLNC

1.89e-03111122PF00630
DomainFILAMIN_REPEAT

FLNA FLNC

1.89e-03111122PS50194
DomainFilamin/ABP280_rpt

FLNA FLNC

1.89e-03111122IPR001298
DomainFilamin/ABP280_repeat-like

FLNA FLNC

1.89e-03111122IPR017868
DomainKelch_2

KLHDC2 KLHDC3

2.66e-03131122IPR011498
DomainKelch_2

KLHDC2 KLHDC3

2.66e-03131122PF07646
DomainIGc2

NPHS1 ADAMTSL1 OBSCN IGSF1 ROBO3 ALPK2

2.94e-032351126SM00408
DomainIg_sub2

NPHS1 ADAMTSL1 OBSCN IGSF1 ROBO3 ALPK2

2.94e-032351126IPR003598
Domain-

KLHDC2 KLHL30 KLHDC3

2.98e-034811232.120.10.80
DomainPX

PXDC1 HS1BP3 SH3PXD2A

3.16e-03491123PF00787
DomainPX

PXDC1 HS1BP3 SH3PXD2A

3.35e-03501123PS50195
DomainIg-like_fold

NPHS1 FLNA FLNC ADAMTSL1 FN1 OBSCN CAMTA2 IL21R IGSF1 ROBO3 ALPK2

3.43e-0370611211IPR013783
Domain-

PXDC1 HS1BP3 SH3PXD2A

3.55e-035111233.30.1520.10
DomainPhox

PXDC1 HS1BP3 SH3PXD2A

3.75e-03521123IPR001683
DomainKelch-typ_b-propeller

KLHDC2 KLHL30 KLHDC3

4.39e-03551123IPR015915
DomainRUN

RUFY1 RUNDC1

5.12e-03181122SM00593
DomainRUN

RUFY1 RUNDC1

5.70e-03191122PS50826
DomainRUN

RUFY1 RUNDC1

5.70e-03191122PF02759
DomainRun_dom

RUFY1 RUNDC1

5.70e-03191122IPR004012
DomainIg_I-set

NPHS1 ADAMTSL1 OBSCN ROBO3 ALPK2

5.77e-031901125IPR013098
DomainI-set

NPHS1 ADAMTSL1 OBSCN ROBO3 ALPK2

5.77e-031901125PF07679
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2

PSMA1 PSMC4 PPARGC1A PPARGC1B GLI2 COL1A1

4.64e-05119776M27785
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

NES FLNA FLNC FN1 CENPF RBBP7 AHCTF1 WDR46 NOC3L NAP1L1 SMC4 ALDH18A1 NIPBL TP53BP1

2.93e-086531131422586326
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NES FLNA FLNC DIS3L2 FN1 PSMA1 AHCTF1 WDR46 NOC3L NAP1L1 SMC4 PSMC4 MCM2 AARSD1 ALDH18A1 PKN2 DHX34 NIPBL TP53BP1

7.47e-0813531131929467282
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

FLNA FLNC NIBAN1 GIT1 RBBP7 PSMA1 NAP1L1 SMC4 IST1 PSMC4 MCM2 RUFY1 AARSD1 NUDT5 MAP1S HPRT1 GET3 UBA6 PRPF39

2.29e-0714551131922863883
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NES FLNA FLNC PSMA1 NOC3L SMC4 IST1 PSMC4 RNF213 AARSD1 FCGBP NUDT5 GET3 UBA6 ALDH18A1 TMED2 TP53BP1 COL1A1

4.39e-0713671131832687490
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

FLNA CENPF AHCTF1 WDR46 NOC3L NAP1L1 SMC4 NIPBL

4.60e-07210113816565220
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SOX4 FLNA FLNC MGAT4B PCNX3 VPS39 KIAA0319L OBSCN PER1 FAAP100 MAP1S OSBPL5 ANKRD11 TIGD3 DHX34 COL1A1

5.98e-0711051131635748872
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NES FLNA FLNC NIBAN1 CENPF SYNE1 WDR46 NAP1L1 SMC4 MCM2 HPRT1 GET3 UBA6 FKBP8 NIPBL

1.20e-0610241131524711643
Pubmed

MEKK4 signaling regulates filamin expression and neuronal migration.

NES FLNA FLNC

1.85e-068113317145501
Pubmed

Novel interactors and a role for supervillin in early cytokinesis.

FLNA PCNX3 CENPF SH3PXD2A

2.04e-0628113420309963
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NES CARMIL2 GIT1 KLHDC2 RBBP7 REEP2 CARD8 SH3PXD2A ANKRD11 FMN2 RAB11FIP5 PRKCG PATJ

4.72e-068611131336931259
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

PCNX3 RBBP7 VPS39 AHCTF1 RNF113A KIAA0319L IST1 HS1BP3 NUDT5 TEX264 CD99 RAB11FIP5 PKN2 FKBP8

5.11e-0610071131434597346
Pubmed

Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.

FLNA KLHDC2 RBBP7 NAP1L1 PSMC4 RNF213 MCM2 ADGRV1 KLHDC3 HPRT1

5.23e-064951131028581483
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

FN1 CENPF OBSCN SMC4 PSMC4 RUFY1 MAP1S ANKRD11 UBA6 FKBP8

5.42e-064971131036774506
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

NES FLNA CENPF RBBP7 AHCTF1 NAP1L1 IST1 MCM2 AARSD1 MAP1S

5.51e-064981131036634849
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

FLNA FLNC FN1 SYNE1 OBSCN RNF213 CARD8

6.73e-06214113722199357
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

FLNA FLNC GIT1 RBBP7 NAP1L1 SOX18 PKN2

6.94e-06215113735973513
Pubmed

Rosiglitazone-induced mitochondrial biogenesis in white adipose tissue is independent of peroxisome proliferator-activated receptor γ coactivator-1α.

PPARGC1A PPARGC1B

1.05e-052113222087241
Pubmed

Structural and functional analysis of the fibronectin-binding protein FNE from Streptococcus equi spp. equi.

FN1 COL1A1

1.05e-052113225290767
Pubmed

Peroxisome proliferator-activated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism.

PPARGC1A PPARGC1B

1.05e-052113217018837
Pubmed

Structural analysis of collagen type I interactions with human fibronectin reveals a cooperative binding mode.

FN1 COL1A1

1.05e-052113223653354
Pubmed

Two independent modes of chromatin organization revealed by cohesin removal.

HPRT1 NIPBL

1.05e-052113229094699
Pubmed

A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance.

PPARGC1A PPARGC1B

1.05e-052113226950361
Pubmed

Promoter methylation of PGC1A and PGC1B predicts cancer incidence in a veteran cohort.

PPARGC1A PPARGC1B

1.05e-052113229888964
Pubmed

Peroxisome proliferator-activated receptor γ coactivator family members competitively regulate hepatitis b virus biosynthesis.

PPARGC1A PPARGC1B

1.05e-052113230419515
Pubmed

Breast cancer cells alter the dynamics of stromal fibronectin-collagen interactions.

FN1 COL1A1

1.05e-052113227503584
Pubmed

The transcriptional coregulator PGC-1β controls mitochondrial function and anti-oxidant defence in skeletal muscles.

PPARGC1A PPARGC1B

1.05e-052113226674215
Pubmed

aPKCλ maintains the integrity of the glomerular slit diaphragm through trafficking of nephrin to the cell surface.

NPHS1 PRKCG

1.05e-052113224700503
Pubmed

Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue.

PPARGC1A PPARGC1B

1.05e-052113230277821
Pubmed

Fatty acid-induced differential regulation of the genes encoding peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in human skeletal muscle cells that have been differentiated in vitro.

PPARGC1A PPARGC1B

1.05e-052113216132959
Pubmed

Hypomorphic mutation of PGC-1beta causes mitochondrial dysfunction and liver insulin resistance.

PPARGC1A PPARGC1B

1.05e-052113217141629
Pubmed

Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3.

SULT1A4 SULT1A3

1.05e-052113229705271
Pubmed

No association between the G482S polymorphism of the proliferator-activated receptor-gamma coactivator-1 (PGC-1) gene and Type II diabetes in French Caucasians.

PPARGC1A PPARGC1B

1.05e-052113212032643
Pubmed

Disconnecting mitochondrial content from respiratory chain capacity in PGC-1-deficient skeletal muscle.

PPARGC1A PPARGC1B

1.05e-052113223707060
Pubmed

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7.

FLNA FLNC

1.05e-05211327689010
Pubmed

PGC-1 proteins and heart failure.

PPARGC1A PPARGC1B

1.05e-052113222939990
Pubmed

PGC1α/β Expression Predicts Therapeutic Response to Oxidative Phosphorylation Inhibition in Ovarian Cancer.

PPARGC1A PPARGC1B

1.05e-052113235131872
Pubmed

[Effect of Danshensu on fibronectin and collagen-1 secretion induced by high glucose in human peritoneal mesothelial cells].

FN1 COL1A1

1.05e-052113221311138
Pubmed

Zinc induces structural reorganization of gelatin binding domain from human fibronectin and affects collagen binding.

FN1 COL1A1

1.05e-052113220541508
Pubmed

Filamin isogene expression during mouse myogenesis.

FLNA FLNC

1.05e-052113210679933
Pubmed

PGC-1alpha/beta induced expression partially compensates for respiratory chain defects in cells from patients with mitochondrial disorders.

PPARGC1A PPARGC1B

1.05e-052113219297390
Pubmed

The PGC-1 coactivators promote an anti-inflammatory environment in skeletal muscle in vivo.

PPARGC1A PPARGC1B

1.05e-052113226159922
Pubmed

A role for peroxisome proliferator-activated receptor γ coactivator 1 (PGC-1) in the regulation of cardiac mitochondrial phospholipid biosynthesis.

PPARGC1A PPARGC1B

1.05e-052113224337569
Pubmed

A novel structural unit in the N-terminal region of filamins.

FLNA FLNC

1.05e-052113224469451
Pubmed

The Potential Use of PGC-1α and PGC-1β to Protect the Retina by Stimulating Mitochondrial Repair.

PPARGC1A PPARGC1B

1.05e-052113226427438
Pubmed

A novel FLNC frameshift and an OBSCN variant in a family with distal muscular dystrophy.

FLNC OBSCN

1.05e-052113229073160
Pubmed

Constitutive Gαi coupling activity of very large G protein-coupled receptor 1 (VLGR1) and its regulation by PDZD7 protein.

PDZD7 ADGRV1

1.05e-052113224962568
Pubmed

Loss of PGC-1α in RPE induces mesenchymal transition and promotes retinal degeneration.

PPARGC1A PPARGC1B

1.05e-052113231101737
Pubmed

Fasting-Induced Transcription Factors Repress Vitamin D Bioactivation, a Mechanism for Vitamin D Deficiency in Diabetes.

PPARGC1A PPARGC1B

1.05e-052113230833469
Pubmed

Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation.

PPARGC1A PPARGC1B

1.05e-052113216679291
Pubmed

Crystal structure of human catecholamine sulfotransferase.

SULT1A4 SULT1A3

1.05e-052113210543947
Pubmed

Peroxisome proliferator-activated receptor-gamma coactivator-1 and insulin resistance: acute effect of fatty acids.

PPARGC1A PPARGC1B

1.05e-052113216896940
Pubmed

Phylogenomic approaches to common problems encountered in the analysis of low copy repeats: the sulfotransferase 1A gene family example.

SULT1A4 SULT1A3

1.05e-052113215752422
Pubmed

Alternative splice variant PGC-1α-b is strongly induced by exercise in human skeletal muscle.

PPARGC1A PPARGC1B

1.05e-052113221862727
Pubmed

[Regulation of collagen type I and fibronectin mRNA expression by mechanical stress in cultured human periodontal ligament fibroblasts].

FN1 COL1A1

1.05e-052113219031824
Pubmed

Human liver thermolabile phenol sulfotransferase: cDNA cloning, expression and characterization.

SULT1A4 SULT1A3

1.05e-05211328117269
Pubmed

Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator-activated receptor-gamma coactivator-1alpha and -1beta in cultured myotubes.

PPARGC1A PPARGC1B

1.05e-052113219906680
Pubmed

Adult expression of PGC-1α and -1β in skeletal muscle is not required for endurance exercise-induced enhancement of exercise capacity.

PPARGC1A PPARGC1B

1.05e-052113227780821
Pubmed

Impact of SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of phenylephrine and salbutamol by human SULT1A3 allozymes.

SULT1A4 SULT1A3

1.05e-052113231145702
Pubmed

Analysis of Metabolic Regulators PGC1-α and PGC1-β in Oral Squamous Cell Carcinoma with and without Hyperglycemia.

PPARGC1A PPARGC1B

1.05e-052113236037136
Pubmed

A genetic variation in the PGC-1 gene could confer insulin resistance and susceptibility to Type II diabetes.

PPARGC1A PPARGC1B

1.05e-052113212107756
Pubmed

Estrogen Signals Through Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease.

PPARGC1A PPARGC1B

1.05e-052113227658772
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

FLNA RBBP7 AHCTF1 NAP1L1 SMC4 RUFY1 NUDT5 PKN2 PATJ TP53BP1

1.28e-055491131038280479
Pubmed

Hereditary Ataxia Overview

SYNE1 FAT2 KCNC3 RNF216 PRKCG

1.30e-0592113520301317
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

FLNA FLNC FN1 RBBP7 NOC3L NAP1L1 SMC4 PSMC4 HPRT1 ALDH18A1 PRPF39 ALPK2

1.34e-058091131232129710
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FLNA NAP1L1 SMC4 PSMC4 RNF213 PKN2 NIPBL TP53BP1

1.36e-05332113832786267
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

FLNA FLNC PSMA1 OBSCN NAP1L1 PSMC4 HPRT1 PATJ

1.42e-05334113830425250
Pubmed

Knockout mice with pituitary malformations help identify human cases of hypopituitarism.

ASXL1 SH3PXD2A ALDH18A1 RUNDC1

1.42e-0545113438822427
Pubmed

Ring finger protein 213 assembles into a sensor for ISGylated proteins with antimicrobial activity.

PSMA1 NAP1L1 IST1 PSMC4 RNF213

1.60e-0596113534599178
Pubmed

Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation.

FN1 SDC3 COL1A1

1.81e-0516113321067603
Pubmed

Netrin1 Produced by Neural Progenitors, Not Floor Plate Cells, Is Required for Axon Guidance in the Spinal Cord.

NES GLI2 ROBO3

1.81e-0516113328434801
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

CENPF WDR46 NAP1L1 SMC4 PSMC4 MCM2 MAP1S HPRT1 PRPF39 NIPBL TP53BP1

1.94e-057041131129955894
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

NES FLNA FLNC CENPF RBBP7 PSMA1 WDR46 NOC3L NAP1L1 PSMC4 MCM2 ALDH18A1 TP53BP1

2.05e-059891131336424410
Pubmed

Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.

FLNA FLNC FN1

2.63e-0518113312119179
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

DIS3L2 GIT1 AARSD1 MAP1S UBA6 PRPF39

3.10e-05183113631932471
Pubmed

A mouse model of brittle cornea syndrome caused by mutation in Zfp469.

FN1 COL1A1

3.13e-053113234368841
Pubmed

PGC-1α induces SPP1 to activate macrophages and orchestrate functional angiogenesis in skeletal muscle.

PPARGC1A HPRT1

3.13e-053113225009290
Pubmed

Interaction of the leucine-rich repeats of polycystin-1 with extracellular matrix proteins: possible role in cell proliferation.

FN1 COL1A1

3.13e-053113211752017
Pubmed

GADD45γ regulates the thermogenic capacity of brown adipose tissue.

PPARGC1A PPARGC1B

3.13e-053113225071184
Pubmed

PDZD7 is a modifier of retinal disease and a contributor to digenic Usher syndrome.

PDZD7 ADGRV1

3.13e-053113220440071
Pubmed

Genomic organization, nucleotide sequence, and cellular distribution of a Shaw-related potassium channel gene, Kv3.3, and mapping of Kv3.3 and Kv3.4 to human chromosomes 19 and 1.

KCNC2 KCNC3

3.13e-05311321740329
Pubmed

Metastatic outgrowth encompasses COL-I, FN1, and POSTN up-regulation and assembly to fibrillar networks regulating cell adhesion, migration, and growth.

FN1 COL1A1

3.13e-053113220489157
Pubmed

Indications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilin.

FLNA FLNC

3.13e-053113211038172
Pubmed

New insights into PGC-1 coactivators: redefining their role in the regulation of mitochondrial function and beyond.

PPARGC1A PPARGC1B

3.13e-053113225495651
Pubmed

PI3K/AKT phosphorylation activates ERRα by upregulating PGC‑1α and PGC‑1β in gallbladder cancer.

PPARGC1A PPARGC1B

3.13e-053113234184087
Pubmed

PGC-1 coactivator activity is required for murine erythropoiesis.

PPARGC1A PPARGC1B

3.13e-053113224662048
Pubmed

Localization and enhanced current density of the Kv4.2 potassium channel by interaction with the actin-binding protein filamin.

FLNA FLNC

3.13e-053113211102480
Pubmed

[Expression and pathobiological significance of Col I, Col IV and Fn in laryngeal squamous cell carcinomas].

FN1 COL1A1

3.13e-053113220359090
Pubmed

A tissue-specific coactivator of steroid receptors, identified in a functional genetic screen.

PPARGC1A PPARGC1B

3.13e-053113210713165
Pubmed

Filamin A negatively regulates the transcriptional activity of p73alpha in the cytoplasm.

FLNA FLNC

3.13e-053113217825253
Pubmed

Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact.

FLNA FLNC

3.13e-053113212393796
Pubmed

Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation.

PPARGC1A PPARGC1B

3.13e-053113217932310
Pubmed

Weighted correlation network analysis identifies FN1, COL1A1 and SERPINE1 associated with the progression and prognosis of gastric cancer.

FN1 COL1A1

3.13e-053113233780362
Pubmed

Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.

FLNA FLNC

3.13e-05311329412467
Pubmed

Association between PPARγ, PPARGC1A, and PPARGC1B genetic variants and susceptibility of gastric cancer in an Eastern Chinese population.

PPARGC1A PPARGC1B

3.13e-053113236587194
Pubmed

Genomic structure and fine mapping of the two human filamin gene paralogues FLNB and FLNC and comparative analysis of the filamin gene family.

FLNA FLNC

3.13e-053113211153914
Pubmed

Kv3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons.

KCNC2 KCNC3

3.13e-053113222673617
Pubmed

Filamins as integrators of cell mechanics and signalling.

FLNA FLNC

3.13e-053113211252955
Pubmed

The F-actin cross-linking and focal adhesion protein filamin A is a ligand and in vivo substrate for protein kinase C alpha.

FLNA FLNC

3.13e-053113212704190
Pubmed

Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer.

PPARGC1A PPARGC1B

3.13e-053113216704985
Pubmed

Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.

PPARGC1A PPARGC1B

3.13e-053113221109195
InteractionHDAC5 interactions

FLNA FN1 GIT1 RBBP7 PSMC4 MCM2 CAMTA2 GLI2 ANKRD11 ALDH18A1 PKN2 PRPF39 COL1A1

9.27e-0743211313int:HDAC5
InteractionARHGAP25 interactions

RBBP7 PSMA1 PER1 UBA6 ALDH18A1

1.07e-05521135int:ARHGAP25
Cytoband19q13.33

LMTK3 CARD8 KASH5 KCNC3

1.42e-04106113419q13.33
GeneFamilyFibronectin type III domain containing|USH2 complex

PDZD7 ADGRV1

9.34e-0547221244
GeneFamilyC2 domain containing protein kinases

PRKCG PKN2

6.89e-0410722835
GeneFamilySulfotransferases, cytosolic

SULT1A4 SULT1A3

1.38e-0314722762
GeneFamilySRY-boxes

SOX4 SOX18

2.56e-0319722757
GeneFamilyFibronectin type III domain containing

NPHS1 FN1 OBSCN ROBO3

3.81e-03160724555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ADAMTSL1 OBSCN ROBO3 ALPK2

3.90e-03161724593
CoexpressionNAKAYA_MYELOID_DENDRITIC_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_UP

AHCTF1 NOC3L SMC4 SLA SLC4A3 SULT1A4 SULT1A3 OSGIN2 PRPF39 NIPBL TP53BP1

1.29e-0639911311M41172
CoexpressionGSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP

OBSCN PER1 SOX18 CR2 SLA IL21R DHX34 NIPBL

2.39e-061981138M4432
CoexpressionJIANG_HYPOXIA_CANCER

FN1 CENPF IST1 E4F1 SLA

5.20e-06581135M7547
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

SOX4 PER1 RNF213 SH3PXD2A ALDH18A1 PATJ TP53BP1

2.56e-051991137M9184
CoexpressionMENON_FETAL_KIDNEY_0_CAP_MESENCHYME_CELLS

SOX4 CENPF NAP1L1 SMC4 ANKRD11

4.47e-05901135M39250
CoexpressionTURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP

FN1 CENPF DGKH COL1A1

5.06e-05471134M7585
CoexpressionKAYO_CALORIE_RESTRICTION_MUSCLE_UP

FLNA FN1 RNF113A KLHDC3 COL1A1

5.51e-05941135M7013
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

AHCTF1 RNF213 ZNF407 DGKH ANKRD11 NIPBL TP53BP1

5.29e-071881137ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTSL1 FN1 SYNE1 ZNF469 ALPK2 COL1A1

6.27e-061781136142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SOX4 DGKH ADGRV1 SH3PXD2A UBA6 PATJ

6.48e-0617911366e965e424eebef50f0202cff75f458be395cfca1
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLNA FLNC SLC4A3 GLI2 IGSF1 COL1A1

6.90e-061811136fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

NIBAN1 FN1 PXDC1 PEG3 SH3PXD2A SDC3

7.58e-061841136684d05340a3dfb8aa08b881516a37f9627a10448
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 SMC4 SLA IL21R CFAP74 FYB1

7.82e-0618511367acc071ea75442817db4d98bd3ed3fff6f0a9d46
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 NES FLNA CENPF ANKRD11 COL1A1

8.06e-06186113615ab6666748a641226e42e6ca6eeaf186a501c95
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 NES FLNA CENPF ANKRD11 COL1A1

8.06e-0618611364ed1b97e2552f3c4134f25665d7513498ffac16c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA SYNE1 RFXAP TEX264 CD99 RAB11FIP5

8.31e-0618711368c69fd469df2915c56ede534cee3ef23d5f64ebf
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-immature_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 SMC4 SLA IL21R CFAP74 FYB1

9.10e-061901136a550806f015d26f809df51a9af04541f2d16a2fc
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX4 NES FLNA NIBAN1 SH3PXD2A ANKRD11

9.10e-061901136d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

NIBAN1 OBSCN SLC4A3 PPARGC1A PATJ ALPK2

9.10e-061901136fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellcontrol-Myeloid-Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

NIBAN1 AHCTF1 TP53INP2 MMP25 PKN2 DHX34

9.38e-061911136db1b3cd07d7d190155b2d14e82e1d124975fbd0b
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF OBSCN PPARGC1A KLHL30 IGSF1 ALPK2

9.38e-061911136543da1197c7e62f2c9cbd4a51414bbaaa6d1a92f
ToppCellfacs-Heart-LV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPF OBSCN PPARGC1A KLHL30 IGSF1 ALPK2

9.38e-0619111369d7d680da3979e256191b534ebd14c5383e0cf93
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

NIBAN1 OBSCN PPARGC1A RNF216 PATJ ALPK2

9.95e-061931136dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCelldroplet-Lung-LUNG-1m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT4B PER1 SLA SDC3 TMED2 PATJ

1.02e-051941136621e0e8fe77ff0be83ea9287ce46e97c47e2b3b9
ToppCelldroplet-Lung-1m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MGAT4B PER1 SLA SDC3 TMED2 PATJ

1.02e-051941136d16ab5f0cfe73afe6c551fd3123d14784a082f56
ToppCellControl-CD8+_Tem|Control / Disease condition and Cell class

FLNA NIBAN1 SYNE1 RNF213 CD99 RAB11FIP5

1.06e-0519511367503b3e032f95b350a2782d28e4d412a8dc9ebcc
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

NIBAN1 CENPF PSMA1 SMC4 SLA FYB1

1.06e-0519511367e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCelldroplet-Limb_Muscle-MUSCLE-1m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 PXDC1 PEG3 PER1 TP53INP2 COL1A1

1.06e-051951136fee9d13f48149cd5f921cfe4b8b3053cf6a6dbd2
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

FLNA CENPF SMC4 ADGRV1 PPARGC1A CD99

1.12e-05197113661749ccafeb938c310cff1de5ff924a1c794325a
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 SYNE1 PEG3 NAP1L1 CD99 COL1A1

1.12e-0519711369af431323da6d099459b7360af40e5df998cffbd
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

FLNA CENPF SMC4 ADGRV1 PPARGC1A CD99

1.12e-0519711369d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCellCD8+_Memory_T_cell-CV-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

SOX4 FLNA GIT1 MCM2 SLA FKBP8

1.12e-0519711369fe3d53346a95c1bbb0fc6a2f2e974889873424b
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial|6_mon / Sample Type, Dataset, Time_group, and Cell type.

FLNA ADGRV1 CD99 FMN2 SDC3 OSGIN2

1.12e-051971136965d5a3f8c9b12cb8a8d3429702ae29ebd8c6122
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon-Macroglial-Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

FLNA ADGRV1 CD99 FMN2 SDC3 OSGIN2

1.12e-0519711363f088eb29197bc575400d6dafd8083e69e4a149f
ToppCellCV-Moderate-3|CV / Virus stimulation, Condition and Cluster

SOX4 FLNA GIT1 MCM2 SLA FKBP8

1.12e-0519711367031286e300eaccf73b927939f8de3a9d2d5fc74
ToppCellControl-Control-Lymphocyte-T/NK-NK_activated|Control / Disease, condition lineage and cell class

FLNA VPS39 SYNE1 RNF213 PDZD7 OSBPL5

1.15e-05198113676d5fe4e5bbe6c73a6ca409b80b5c3924e07cab7
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FN1 SYNE1 PEG3 NAP1L1 CD99 COL1A1

1.15e-051981136a883e25cb7a78b2ecfb15cef4633bdd02dfafb12
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

SOX4 ADAMTSL1 FN1 SH3PXD2A GLI2 COL1A1

1.18e-0519911365b9d355795dd03a22f0961dfd143425c367a4654
ToppCellHSPCs|World / Lineage and Cell class

PSMA1 NAP1L1 SMC4 MCM2 NUDT5 HPRT1

1.18e-051991136df1ffc416c6946f1ba182f242a50ee41a571d565
ToppCelldroplet-Liver-nan-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0319L UBA6 ALDH18A1 SDC3 TP53BP1

1.82e-05127113539fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ASXL1 FN1 PXDC1 ZNF407 ALPK2

4.59e-051541135e65e4636646164610f33f7bbac0d879a3ea55986
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA RNF113A NAP1L1 GLI2 COL1A1

4.88e-051561135d5207dbfbcfb885557ea1378dfe6a56d7102e94a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA RNF113A NAP1L1 GLI2 COL1A1

4.88e-051561135363f1b661048d25895e2b8681c82894c957b29c0
ToppCellE16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF213 SLA MMP25 IL21R FYB1

5.67e-0516111355a8698790f9aba796dd2b64af419055c60bd7de8
ToppCell390C-Lymphocytic-ILC-ILC-2|390C / Donor, Lineage, Cell class and subclass (all cells)

HS1BP3 TP53INP2 SULT1A3 OSGIN2 TP53BP1

6.93e-0516811352781dd6b369427a94c5059b44b4c8f023f5f2988
ToppCell368C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

SOX4 KLHDC2 TEX264 NIPBL

7.48e-05881134142d2e00ef19c0ad011a21945bf1111271056eae
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HS1BP3 TP53INP2 WDR97 OSGIN2 TP53BP1

7.54e-05171113570963f79711fe6088d6d01b29206b17ab89e5e73
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 LMTK3 SLC4A3 NACAD PRKCG

7.96e-051731135e944ea3a0a368f856efacbda4600605cf751dd9c
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 LMTK3 SLC4A3 NACAD PRKCG

7.96e-05173113585fa5918e9c1f6bb4757e3350cfc71ee75c55640
ToppCellfacs-MAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMC4 SLA KCNC2 IL21R FYB1

8.63e-051761135359a57aea89d8e6776eaefb0c3553a0dbcad5e58
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC NIBAN1 FN1 COL1A1

9.10e-051781135c661246269ce26c4fc62e12f86c5f90a2dcfdce0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Degenerative_Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FLNC NIBAN1 FN1 COL1A1

9.10e-051781135e5e5f5b4a27e120a1076b1cb250fa25d0c336956
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

SYNE1 SLA ZNF469 IL21R ALPK2

9.35e-051791135cc079ba015326dccde955c5eafa3e4a2e40de192
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SOX4 NIBAN1 ADAMTSL1 ADGRV1 PATJ

9.60e-051801135b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

NIBAN1 FN1 PEG3 SH3PXD2A SDC3

9.85e-05181113556ae86072858c156681507aecd1bc6cb0a3372d2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA NIBAN1 FN1 GLI2 COL1A1

1.04e-041831135667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Lymphocytic-lymphocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CARMIL2 CR2 IL21R PATJ FYB1

1.04e-041831135a305667cfdae50e64e1890f10f71b407ae617b80
ToppCellCF-Myeloid-Neutrophil|CF / Disease state, Lineage and Cell class

NIBAN1 SLA MMP25 FYB1 DHX34

1.04e-041831135da43827952e6fdee2ce94648c316182f272b321c
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

FLNC NIBAN1 OBSCN SLC4A3 ALPK2

1.06e-041841135e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-4|TCGA-Thryoid / Sample_Type by Project: Shred V9

NIBAN1 MGAT4B FN1 MCM2 OSGIN2

1.06e-041841135d9659d1e4465fec68f48a22edef443f354f6c7cf
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

FLNA NIBAN1 SYNE1 RNF213 CD99

1.09e-041851135097d628f92e13250c15b550f2fd1f4225fc07558
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 SMC4 SLA IL21R CFAP74

1.09e-041851135aa2c36e2cce0f0a536cd1dfc3788b6fee6f21b6b
ToppCelldroplet-Lung-LUNG-1m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA PER1 SLA SDC3 PATJ

1.09e-04185113553a5218c1e6eb12daccde3d6e02f337e2586d74c
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A3 PPARGC1A KLHL30 IGSF1 ALPK2

1.12e-041861135337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A3 PPARGC1A KLHL30 IGSF1 ALPK2

1.12e-041861135e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 CENPF SMC4 GLI2 COL1A1

1.15e-041871135e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FN1 CENPF SMC4 GLI2 COL1A1

1.15e-041871135cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCellfacs-Heart-Unknown-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN SLC4A3 PPARGC1A KLHL30 ALPK2

1.15e-0418711350ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCellfacs-Heart-Unknown|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN SLC4A3 PPARGC1A KLHL30 ALPK2

1.15e-041871135362e56426a568423a81e8a30e3ecf99b76135843
ToppCellRV-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

OBSCN CPEB3 PPARGC1B PATJ ALPK2

1.15e-04187113578cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCellfacs-Heart-Unknown-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN SLC4A3 PPARGC1A KLHL30 ALPK2

1.15e-041871135c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCellLA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

NIBAN1 OBSCN SLC4A3 PPARGC1A ALPK2

1.18e-0418811356d249fe92d51a19da19ec14bb2262d394255d577
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LMTK3 KCNC3 PRKCG PATJ ALPK2

1.18e-0418811351efbc99bcd6542e5d9fa91edb7c4295167914786
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 PXDC1 ANKRD11 PKN2 NIPBL

1.18e-041881135d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NIBAN1 ADAMTSL1 ADGRV1 FCGBP PATJ

1.18e-0418811350d86044bc340e3efb90d0022dd299873639d831c
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 SMC4 SLA CFAP74 FYB1

1.21e-041891135a1773ef8fe4518d8f3b17c6fb2c3ff3bbc4d79ad
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

NIBAN1 OBSCN PPARGC1A PATJ ALPK2

1.21e-0418911359c1debd65c13d63fd4f3158917d621b44b714c26
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A3 PPARGC1A KLHL30 IGSF1 ALPK2

1.21e-041891135e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC4A3 PPARGC1A KLHL30 IGSF1 ALPK2

1.21e-041891135b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellRV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

FLNC NIBAN1 OBSCN PPARGC1A ALPK2

1.21e-0418911350a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

FLNC NIBAN1 OBSCN PPARGC1A ALPK2

1.24e-04190113593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellMesenchymal-airway_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

SOX4 FLNA FLNC GLI2 COL1A1

1.24e-041901135645e56b02edc3702c7db917b8ecd5eed0decaf71
ToppCell3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-T_cell-T_cells_proliferating-T_cells_proliferating_L.1.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF SMC4 MCM2 HPRT1 IL21R

1.24e-041901135b69940d16685249167d4c2cf6ad8237ccf6f7590
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

FLNA NIBAN1 SYNE1 RNF213 CD99

1.24e-04190113566d29f53f129fc18771f6214316a913eeaccd55e
ToppCellLA-03._Atrial_Cardiomyocyte|LA / Chamber and Cluster_Paper

NIBAN1 OBSCN SLC4A3 PPARGC1A ALPK2

1.27e-0419111355d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCellInfluenza_Severe-Non-classical_Monocyte|Influenza_Severe / Disease group and Cell class

SOX4 NAP1L1 PPARGC1B KNDC1 SDC3

1.27e-041911135197edf6feb1cfc71d88e532d74f77305a42a3486
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA FN1 SH3PXD2A GLI2 COL1A1

1.27e-04191113504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCelldroplet-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 CENPF SMC4 SLA FYB1

1.30e-041921135041124dd5c24c1eb188d2560ba606422c0b215c5
ToppCellLV-04._Ventricular_Cardiomyocyte_I|LV / Chamber and Cluster_Paper

NIBAN1 OBSCN PPARGC1A PATJ ALPK2

1.30e-041921135ad19e2c1d36a0566c9b12ced10db78f4781c8ea6
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-immature_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 SMC4 SLA IL21R FYB1

1.30e-0419211357ad0aa18d6debe0dc26dbb0d33be656b734b5e73
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SOX4 FLNA FN1 FYB1 COL1A1

1.30e-0419211358171a60df481195c39a7f740effcae8e4deb6ca7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ADAMTSL1 KIAA0319L SMC4 ADGRV1 PATJ

1.30e-04192113529f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SOX4 SMC4 SLA IL21R FYB1

1.30e-0419211357299a0bbba8998cff4c6fd136f7e2d644ee5bd45
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 FN1 SOX18 SYT15B OSBPL5

1.33e-041931135daefbfd3a3dd1351fbe94b9abfd807db44d56c24
ToppCellControl-CD8+_T_naive|Control / Disease condition and Cell class

SOX4 OBSCN NAP1L1 FCGBP FYB1

1.33e-041931135627d345baf1940218c61907305705298e473dbab
ToppCellPND01|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FN1 PEG3 NAP1L1 PER1 ANKRD11

1.33e-041931135c291345c11cfcbceacbdc001a5851f67478a2779
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPHS1 FLNA FN1 CR2 ALPK2

1.36e-041941135f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellsevere-Myeloid-CD16_Monocytes|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SOX4 NAP1L1 KCNC3 KNDC1 SDC3

1.36e-0419411351b33248b8a7cb914783bcf9e6a80481b4db7e0e8
ToppCellPCW_07-8.5|World / Celltypes from embryonic and fetal-stage human lung

NES CENPF NAP1L1 SMC4 DGKH

1.36e-0419411355759c83308df017f1faae248e9b85388e25254f0
ToppCellfacs-Skin-Telogen-3m-Epithelial|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBBP7 AHCTF1 PEG3 PER1 TMED2

1.36e-0419411354d7fc4d0a55abb3b645116d13a983bbedc55f70c
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA FN1 CENPF PXDC1 COL1A1

1.36e-041941135775600880bb77781de48085d8744c1030223de1f
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 ANKRD11 PKN2 NIPBL COL1A1

1.36e-041941135e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FLNA NIBAN1 SYNE1 GET3 OSBPL5

1.36e-04194113524837a27b0041fe8c348225fa8b09b127d743603
ToppCellfacs-Skin-Telogen-3m|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBBP7 AHCTF1 PEG3 PER1 TMED2

1.36e-041941135ba10fc5929649bb994c3f1d2ce6ca3167fa9b11b
ToppCellHSPCs-Mk_prog.|HSPCs / Lineage and Cell class

OBSCN SLA REEP2 ROBO3 FYB1

1.36e-0419411355c05d508f5c29e6efe87506bf59e3b0fe5922f65
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

FLNA NIBAN1 SYNE1 CD99 OSBPL5

1.36e-041941135ecdfc27d06e363fb23f0309f26ef6404a89f14ec
ToppCelldroplet-Pancreas-Exocrine-21m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA FN1 CENPF PXDC1 COL1A1

1.36e-04194113504ecb609d233a4b12e275c604810937830363e17
DiseaseUsher syndrome, type 2C

PDZD7 ADGRV1

1.23e-0521042C2931213
DiseaseUSHER SYNDROME, TYPE IIC

PDZD7 ADGRV1

1.23e-0521042605472
DiseaseUsher syndrome type 2C

PDZD7 ADGRV1

1.23e-0521042cv:C2931213
DiseaseUsher syndrome type 2C (is_implicated_in)

PDZD7 ADGRV1

1.23e-0521042DOID:0110839 (is_implicated_in)
Diseasemyofibrillar myopathy 5 (implicated_via_orthology)

FLNA FLNC

3.68e-0531042DOID:0080096 (implicated_via_orthology)
Diseasedistal muscular dystrophy 4 (implicated_via_orthology)

FLNA FLNC

3.68e-0531042DOID:0111190 (implicated_via_orthology)
DiseaseLupus Erythematosus, Systemic

PCNX3 KIAA0319L CR2 IL21R

1.18e-04711044C0024141
DiseaseMalignant neoplasm of breast

FLNA FN1 CENPF VPS39 SYNE1 PXDC1 OBSCN PER1 RUFY1 PPARGC1B NIPBL TP53BP1

4.05e-04107410412C0006142
DiseaseAortic Valve Insufficiency

FN1 COL1A1

6.63e-04111042C0003504
DiseaseLibman-Sacks Disease

PCNX3 CR2 IL21R

1.14e-03581043C0242380
Diseaserespiratory symptom change measurement, response to placebo

PPARGC1A PKN2

1.62e-03171042EFO_0008344, EFO_0010068
DiseaseMammary Carcinoma, Human

FLNA FN1 CENPF VPS39 SYNE1 PPARGC1B TP53BP1

2.61e-035251047C4704874
DiseaseMammary Neoplasms, Human

FLNA FN1 CENPF VPS39 SYNE1 PPARGC1B TP53BP1

2.61e-035251047C1257931
DiseaseMammary Neoplasms

FLNA FN1 CENPF VPS39 SYNE1 PPARGC1B TP53BP1

2.67e-035271047C1458155
Diseasedilated cardiomyopathy (implicated_via_orthology)

FLNC CENPF PPARGC1A

2.87e-03801043DOID:12930 (implicated_via_orthology)
DiseaseBreast Carcinoma

FLNA FN1 CENPF VPS39 SYNE1 PPARGC1B TP53BP1

2.99e-035381047C0678222
Diseasenephrotic syndrome (biomarker_via_orthology)

NPHS1 PPARGC1A

3.23e-03241042DOID:1184 (biomarker_via_orthology)
Diseasethalamus volume

ADGRV1 PPARGC1A SDC3

3.41e-03851043EFO_0006935
DiseaseLeft Ventricular Hypertrophy

FN1 COL1A1

3.50e-03251042C0149721

Protein segments in the cluster

PeptideGeneStartEntry
LELGGSEATPEDDPL

SLC4A3

661

P48751
ADAFAGPEDDLDLGP

ANKRD11

2121

Q6UB99
AAEAQPLEGFGEVPE

ALPK2

1996

Q86TB3
PGELEGLFFPEEKEE

CARMIL2

921

Q6F5E8
DFIPSSGELIFEPGE

ADGRV1

3586

Q8WXG9
EALFGGPVGASELEP

CAMTA2

486

O94983
EDTVLFPEGGGQPDD

AARSD1

46

Q9BTE6
LDGDLDPGLPSTEDV

GIT1

631

Q9Y2X7
APDGGFDLSDALPDN

CD99

21

P14209
PSPDGDRDIFIDGVV

DIS3L2

86

Q8IYB7
PGDLTAEEGLDPLDS

ASXL1

941

Q8IXJ9
EECSFELPPGALDGL

RAB11FIP5

71

Q9BXF6
FAPPEVPESGDLDDD

NAP1L1

301

P55209
PEAEEPANLESFGGE

KASH5

136

Q8N6L0
EEEAGEEPTPGLGNF

KLHL30

281

Q0D2K2
LPPFEDESEGLLGTE

MCM2

46

P49736
TELGLPPGEEVDAVF

MMP25

406

Q9NPA2
AGDLDTLEPDSLPFE

NPHS1

1221

O60500
LPPDLGSVDVGEEQD

PCDHA8

776

Q9Y5H6
LDIFETPDLIGGDPG

KCNC2

166

Q96PR1
PLAPGAADSDEDTEG

MAP1S

801

Q66K74
AEGEVDPAFGPLEAL

MGAT4B

511

Q9UQ53
GDEEPPFVLLDTDAA

GUCY2D

396

Q02846
TADDLGFLPEDDVPH

KIAA0319L

136

Q8IZA0
GFPGADPDDVLTVTE

LMTK3

456

Q96Q04
EIPEFNPDETDGLFG

ADAMTSL1

586

Q8N6G6
DDPLFSELDGLGLEP

PER1

1216

O15534
PLLEGGGFFEDEDTS

PCNX3

411

Q9H6A9
FLDASDPDLGPAGEV

FAT2

946

Q9NYQ8
CIEFPAGLIDDGETP

NUDT5

91

Q9UKK9
LLPVNGFPEEEDNGE

PDZD7

676

Q9H5P4
APGVVGPAEADIDFD

FLNC

806

Q14315
DGIEEEDADDGFPAP

FYB1

626

O15117
DNLGSDDPEGDIPVL

NIPBL

81

Q6KC79
SEEFEDLGTEAPFLP

NES

1366

P48681
LGDLTALDDTPPGAD

GLI2

691

P10070
GQPPFDGEDEEELFQ

PRKCG

551

P05129
DDDVSPFLEGLEERP

PSMA1

226

P25786
IDPFGATPFIDPDLD

DGKH

746

Q86XP1
GGASDLPEDPDEDAI

RNF113A

326

O15541
GGALAPSDSEDPFLD

FAAP100

611

Q0VG06
PDVIIGEGPTDSEFF

PEG3

31

Q9GZU2
GDDLPSGIEDITDPA

PRPF39

286

Q86UA1
SDVEGLFDSPPGSDD

ALDH18A1

266

P54886
EDAEDGPPELLFIHG

RBBP7

356

Q16576
PGVVISDDEPGYDLD

HPRT1

6

P00492
LFLSADEGPAEPEEP

OBSCN

5031

Q5VST9
LDSLPVDEDGLPSFD

PPARGC1A

96

Q9UBK2
DSPAHLEIEGEDFPF

OSGIN2

266

Q9Y236
AGVPPLEDFEVLDGV

FKBP8

16

Q14318
PLPGVEFVLEHDGEE

IGSF1

1186

Q8N6C5
FDEEVDPDEGLFGPG

HS1BP3

231

Q53T59
FDDPDLGGAIPLGDS

HS1BP3

266

Q53T59
DPDPEEGVNFILIGE

CR2

306

P20023
TEGTEFEPEGLPEVV

CENPF

2971

P49454
GGLPPDIDEDEITAS

CPEB3

446

Q8NE35
GDPADDFLTPDGALA

FCGBP

616

Q9Y6R7
DFLTPDGALAPDAVE

FCGBP

621

Q9Y6R7
APGVVGPAEADIDFD

FLNA

811

P21333
EDGIHELFPAPDGEE

FN1

1761

P02751
ELFPAPDGEEDTAEL

FN1

1766

P02751
GGPLFDVTAEPEEAV

CARD8

231

Q9Y2G2
DPSLGVAELPDEFFE

GET3

106

O43681
EAPPGVETDLIDVGF

IST1

186

P53990
EDLRADDLPGPAFES

KLHDC2

6

Q9Y2U9
PSPEEGLGDEFDLID

KLHDC3

311

Q9BQ90
DDPEGAFVPPEFDVT

KNDC1

101

Q76NI1
DDGYPALDLDAGLEP

IL21R

396

Q9HBE5
GEVEPGDFASSDVLP

AHCTF1

1601

Q8WYP5
GFLGLPAPFSEEDED

E4F1

41

Q66K89
EDAFEDAPRGSPGEE

FMN2

351

Q9NZ56
DGPPGAEEAALETLQ

DHX34

1096

Q14147
GGPSGDFELPEEETT

SDC3

311

O75056
FVEGGDPLDVPVESL

CFAP74

1481

Q9C0B2
ESQGSGVFLPELDEP

NOC3L

666

Q8WTT2
PELSDEEQDGDFVPG

OSBPL5

786

Q9H0X9
PEGTENPLGVDESLF

SLA

211

Q13239
FLEEATAEEPGAAPG

RUNDC1

56

Q96C34
ADPSDPLGLYEEEGA

SOX4

316

Q06945
NGSEFPSELEDGDDP

PXDC1

196

Q5TGL8
GLSFLGPEPEDLEDL

PSMC4

26

P43686
EGTEDLDGELLPTPS

SYNE1

5826

Q8NF91
PGSALEPGEEFEIVD

RUFY1

26

Q96T51
DDIPEDDVGLAAFPA

PPARGC1B

101

Q86YN6
EDDYGEFLDLGPPGI

RNF216

71

Q9NWF9
GEDEADLLDTSDPPG

RFXAP

86

O00287
LVGESPFPGDDEEEV

PKN2

851

Q16513
ENGILGLGPFPTEDE

OXCT2

341

Q9BYC2
GLGPFPTEDEVDADL

OXCT2

346

Q9BYC2
FLEVNDPGEPSGLET

SULT1A4

81

P0DMN0
FLEVNDPGEPSGLET

SULT1A3

81

P0DMM9
DVAPLDVGAPDQEFG

COL1A1

1441

P02452
LDRAADFLSEPEGGP

RNF213

4236

Q63HN8
DEKGDREGAFEPLPT

TIGD3

416

Q6B0B8
VSFAPDIDGDEDLPG

UBA6

1026

A0AVT1
PGSLLDTIEDLGDDP

REEP2

176

Q9BRK0
FGGTLEDEEPAQEEP

NIBAN1

686

Q9BZQ8
PDAALPDGDLSEGEL

TP53INP2

126

Q8IXH6
LPEREEGEGEETPNF

PATJ

1046

Q8NI35
PAFGFDSEPELSEEP

SH3PXD2A

561

Q5TCZ1
DADGYDVPDPGLLTE

WDR97

21

A6NE52
CLEGPEEELEGSSEP

ROBO3

1096

Q96MS0
LEAESLEPPSEFGDL

SYT15B

321

X6R8R1
SSFEELDLEGEGPLG

TEX264

271

Q9Y6I9
GGDAELELVDSLDPF

SMC4

1156

Q9NTJ3
LEPEPGGSEDCDVLE

PRPF40B

216

Q6NWY9
LPDGPTGSSEEEEEF

TP53BP1

1751

Q12888
LLLAEEPGFLEGEDG

WDR46

151

O15213
EDPAGLPESFLLDGF

ZNF469

2901

Q96JG9
EGGFLDIDVEITGPD

TMED2

51

Q15363
PDTPFGDIVGLDLGE

TTC36

16

A6NLP5
ERSPLDGLEPGEAAF

SOX18

216

P35713
PDGLEGPELSSFEGI

ZNF142

731

P52746
EDGGPVSDVIASFPE

ZNF407

31

Q9C0G0
TPVPAGEEEGELGEY

VPS39

646

Q96JC1
EEALDSFEAPDPAGA

KCNC3

196

Q14003
EALSLPEPASGAGEE

NACAD

1026

O15069
PEPASGAGEEIAEAL

NACAD

1031

O15069
EDSVEDEEPPGSLGL

NACAD

1256

O15069