Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN3 NRXN1	3.51e-05	5	38	2	GO:0097109
GeneOntologyBiologicalProcess	postsynaptic density assembly	NRXN3 NRXN1 SIPA1L1	3.59e-05	34	39	3	GO:0097107
GeneOntologyBiologicalProcess	transition metal ion transport	ABCB7 SLC31A1 SLC39A8 CLTC	6.06e-05	113	39	4	GO:0000041
GeneOntologyBiologicalProcess	postsynaptic specialization assembly	NRXN3 NRXN1 SIPA1L1	7.84e-05	44	39	3	GO:0098698
GeneOntologyBiologicalProcess	excitatory synapse assembly	NRXN3 NRXN1 SIPA1L1	8.97e-05	46	39	3	GO:1904861
GeneOntologyBiologicalProcess	postsynaptic density organization	NRXN3 NRXN1 SIPA1L1	1.79e-04	58	39	3	GO:0097106
Domain	MOR2-PAG1_mid	FRY FRYL	4.03e-06	2	38	2	PF14228
Domain	MOR2-PAG1_C	FRY FRYL	4.03e-06	2	38	2	PF14225
Domain	MOR2-PAG1_N	FRY FRYL	4.03e-06	2	38	2	PF14222
Domain	Cell_morpho_N	FRY FRYL	4.03e-06	2	38	2	IPR025614
Domain	Cell_Morphogen_C	FRY FRYL	4.03e-06	2	38	2	IPR025481
Domain	MOR2-PAG1_mid	FRY FRYL	4.03e-06	2	38	2	IPR029473
Domain	Syndecan	NRXN3 NRXN1	8.41e-05	7	38	2	PF01034
Domain	Syndecan/Neurexin_dom	NRXN3 NRXN1	8.41e-05	7	38	2	IPR027789
Domain	Neurexin-like	NRXN3 NRXN1	3.61e-04	14	38	2	IPR003585
Domain	4.1m	NRXN3 NRXN1	3.61e-04	14	38	2	SM00294
Domain	LAM_G_DOMAIN	NRXN3 NRXN1	2.71e-03	38	38	2	PS50025
Domain	Laminin_G_2	NRXN3 NRXN1	2.99e-03	40	38	2	PF02210
Domain	LamG	NRXN3 NRXN1	3.61e-03	44	38	2	SM00282
Domain	ARM-type_fold	CKAP5 FRYL CLTC EFR3A	4.84e-03	339	38	4	IPR016024
Pubmed	The contribution of rare and common variants in 30 genes to risk nicotine dependence.	ANKK1 NRXN3 NRXN1	4.70e-07	14	39	3	25450229
Pubmed	Association of a polymorphism in the NRXN3 gene with the degree of smoking in schizophrenia: a preliminary study.	NRXN3 NRXN1	1.23e-06	2	39	2	19658047
Pubmed	Cytoskeleton-associated protein 5 and clathrin heavy chain binding regulates spindle assembly in mouse oocytes.	CKAP5 CLTC	1.23e-06	2	39	2	28177917
Pubmed	Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.	NRXN3 NRXN1	1.23e-06	2	39	2	37543682
Pubmed	Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.	NRXN3 NRXN1	1.23e-06	2	39	2	9430716
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	FANCD2 SRP54 BRCC3 MCMBP CPSF2 HNRNPLL LANCL2 NDUFS1 DHX9 CLTC	1.54e-06	1335	39	10	29229926
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	CKAP5 FRYL DHX9 CLTC ITPR3	3.08e-06	202	39	5	33005030
Pubmed	Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.	NRXN3 NRXN1	3.67e-06	3	39	2	34133920
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN3 NRXN1	3.67e-06	3	39	2	38891114
Pubmed	Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.	NRXN3 NRXN1	3.67e-06	3	39	2	12036300
Pubmed	β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.	NRXN3 NRXN1	3.67e-06	3	39	2	26213384
Pubmed	Neurexin gene family variants as risk factors for autism spectrum disorder.	NRXN3 NRXN1	3.67e-06	3	39	2	29045040
Pubmed	Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.	NRXN3 NRXN1	3.67e-06	3	39	2	31005376
Pubmed	Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.	NRXN3 NRXN1	3.67e-06	3	39	2	38571813
Pubmed	Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.	NRXN3 NRXN1	3.67e-06	3	39	2	35173587
Pubmed	The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.	NRXN3 NRXN1	3.67e-06	3	39	2	30858964
Pubmed	Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOG.	CKAP5 CLTC	3.67e-06	3	39	2	22891263
Pubmed	Neurexins are differentially expressed in the embryonic nervous system of mice.	NRXN3 NRXN1	3.67e-06	3	39	2	7722633
Pubmed	Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.	NRXN3 NRXN1	3.67e-06	3	39	2	26446217
Pubmed	Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.	NRXN3 NRXN1	3.67e-06	3	39	2	28013231
Pubmed	Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.	CKAP5 CLTC	3.67e-06	3	39	2	20566684
Pubmed	Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.	NRXN3 NRXN1	3.67e-06	3	39	2	11944992
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN3 NRXN1	3.67e-06	3	39	2	16406382
Pubmed	Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.	NRXN3 NRXN1	3.67e-06	3	39	2	33058888
Pubmed	Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.	NRXN3 NRXN1	3.67e-06	3	39	2	17035546
Pubmed	Neurexins: three genes and 1001 products.	NRXN3 NRXN1	3.67e-06	3	39	2	9448462
Pubmed	Deletion of α-neurexin II results in autism-related behaviors in mice.	NRXN3 NRXN1	3.67e-06	3	39	2	25423136
Pubmed	Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.	NRXN3 NRXN1	3.67e-06	3	39	2	31812984
Pubmed	Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.	NRXN3 NRXN1	7.34e-06	4	39	2	14983056
Pubmed	CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.	NRXN3 NRXN1	7.34e-06	4	39	2	8786425
Pubmed	Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.	NRXN3 NRXN1	7.34e-06	4	39	2	17347997
Pubmed	Neurexins cluster Ca2+ channels within the presynaptic active zone.	NRXN3 NRXN1	7.34e-06	4	39	2	32134527
Pubmed	Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.	NRXN3 NRXN1	7.34e-06	4	39	2	32706374
Pubmed	A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging.	CKAP5 CLTC	7.34e-06	4	39	2	21297582
Pubmed	Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.	NRXN3 NRXN1	7.34e-06	4	39	2	35385735
Pubmed	Neurexins regulate presynaptic GABAB-receptors at central synapses.	NRXN3 NRXN1	7.34e-06	4	39	2	33888718
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	CKAP5 CPSF2 LANCL2 DHX9 CLTC ITPR3 EFR3A	1.15e-05	701	39	7	30196744
Pubmed	Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.	NRXN3 NRXN1	1.22e-05	5	39	2	28472659
Pubmed	Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.	NRXN3 NRXN1	1.22e-05	5	39	2	36709330
Pubmed	Neuroligins and neurexins link synaptic function to cognitive disease.	NRXN3 NRXN1	1.22e-05	5	39	2	18923512
Pubmed	Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.	NRXN3 NRXN1	1.22e-05	5	39	2	20537373
Pubmed	Distinct neurexin-cerebellin complexes control AMPA- and NMDA-receptor responses in a circuit-dependent manner.	NRXN3 NRXN1	1.22e-05	5	39	2	36205393
Pubmed	Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.	NRXN3 NRXN1	1.22e-05	5	39	2	9223334
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	CKAP5 WDR35 NRXN3 NRXN1	1.30e-05	128	39	4	30995482
Pubmed	Structures, alternative splicing, and neurexin binding of multiple neuroligins.	NRXN3 NRXN1	1.83e-05	6	39	2	8576240
Pubmed	Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.	NRXN3 NRXN1	1.83e-05	6	39	2	30683685
Pubmed	Loss of GGN leads to pre-implantation embryonic lethality and compromised male meiotic DNA double strand break repair in the mouse.	FANCD2 BRCC3	1.83e-05	6	39	2	23451117
Pubmed	Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.	NRXN3 NRXN1	1.83e-05	6	39	2	12827191
Pubmed	Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn.	NRXN3 NRXN1	1.83e-05	6	39	2	19816407
Pubmed	Glycosylation of Cblns attenuates their receptor binding.	NRXN3 NRXN1	2.56e-05	7	39	2	29782851
Pubmed	Neurexophilin binding to alpha-neurexins. A single LNS domain functions as an independently folding ligand-binding unit.	NRXN3 NRXN1	2.56e-05	7	39	2	9856994
Pubmed	Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.	LRTM2 NRXN3 NRXN1	2.77e-05	52	39	3	24613359
Pubmed	GluD1 is a signal transduction device disguised as an ionotropic receptor.	NRXN3 NRXN1	3.42e-05	8	39	2	34135511
Pubmed	Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.	NRXN3 NRXN1	3.42e-05	8	39	2	30871858
Pubmed	Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.	NRXN3 NRXN1	3.42e-05	8	39	2	37591863
Pubmed	Defining the membrane proteome of NK cells.	CKAP5 ADIPOR1 CPSF2 HNRNPLL VPS50 DHX9 CLTC ITPR3	3.85e-05	1168	39	8	19946888
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	FANCD2 CKAP5 SRP54 CPSF2 HNRNPLL DHX9	4.37e-05	582	39	6	20467437
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	NRXN3 NRXN1	4.39e-05	9	39	2	9707552
Pubmed	Molecular self-avoidance in synaptic neurexin complexes.	NRXN3 NRXN1	4.39e-05	9	39	2	34919427
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	FANCD2 MCMBP ABCB7 LANCL2 NDUFS1 DHX9 CLTC	4.85e-05	878	39	7	37223481
Pubmed	An N-terminal SIAH-interacting motif regulates the stability of the ubiquitin specific protease (USP)-19.	CKAP5 ECEL1	5.48e-05	10	39	2	23500468
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	SRP54 BRCC3 CPSF2 LANCL2 DHX9 CLTC	5.93e-05	615	39	6	31048545
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	MCMBP HNRNPLL LANCL2 NDUFS1 SIPA1L1 DHX9 CLTC ITPR3	6.10e-05	1247	39	8	27684187
Pubmed	SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.	NRXN3 NRXN1	6.70e-05	11	39	2	32973045
Pubmed	Polymorphisms in mitochondrial genes and prostate cancer risk.	FANCD2 NDUFS1 SLC39A8	8.00e-05	74	39	3	19064571
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CKAP5 FRY CPSF2 NRXN1 SIPA1L1 RASAL1 CLTC	8.66e-05	963	39	7	28671696
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	FANCD2 CKAP5 BRCC3 MCMBP HNRNPLL LANCL2 ITPR3	9.30e-05	974	39	7	28675297
Pubmed	A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.	SRP54 NRXN3 SLC31A1 NDUFS1 DHX9	1.02e-04	419	39	5	28700943
Pubmed	Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair.	FANCD2 DHX9	1.46e-04	16	39	2	31980815
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	FANCD2 BRCC3 MCMBP CPSF2 CLTC ITPR3 EFR3A	1.47e-04	1049	39	7	27880917
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	FANCD2 CKAP5 MCMBP HNRNPLL LANCL2 NDUFS1 DHX9 CLTC	1.54e-04	1425	39	8	30948266
Pubmed	MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.	NRXN3 NRXN1	1.65e-04	17	39	2	27779093
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	SRP54 CPSF2 NRXN1 HNRNPLL NDUFS1 DHX9 CLTC	1.78e-04	1082	39	7	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SRP54 FRYL ABCB7 CPSF2 LANCL2 SIPA1L1 CLTC	1.80e-04	1084	39	7	11544199
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	BRCC3 ABCB7 VPS50 CUEDC1 ITPR3	1.94e-04	481	39	5	28190767
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SRP54 MCMBP ABCB7 NDUFS1 DHX9 CLTC ITPR3 EFR3A	2.06e-04	1487	39	8	33957083
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FANCD2 CKAP5 CPSF2 SIPA1L1 DHX9 CLTC	2.08e-04	774	39	6	15302935
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	FANCD2 SRP54 ABCB7 NDUFS1 MMUT DHX9 CLTC ITPR3	2.15e-04	1496	39	8	32877691
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	CKAP5 SRP54 CPSF2 HNRNPLL NDUFS1 SIPA1L1 CUEDC1 EFR3A	2.16e-04	1497	39	8	31527615
Pubmed	Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt.	CKAP5 MCMBP ABCB7 CLTC	2.39e-04	271	39	4	25737280
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CKAP5 NRXN1 HNRNPLL NDUFS1 SIPA1L1 RASAL1 CLTC	2.44e-04	1139	39	7	36417873
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	CPSF2 SIPA1L1 DHX9 CLTC	2.50e-04	274	39	4	34244482
Pubmed	Cbln1 regulates axon growth and guidance in multiple neural regions.	NRXN3 NRXN1	2.79e-04	22	39	2	36395107
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	CKAP5 SRP54 BRCC3 NDUFS1 MMUT	3.13e-04	534	39	5	35032548
Pubmed	Systematic Determination of Human Cyclin Dependent Kinase (CDK)-9 Interactome Identifies Novel Functions in RNA Splicing Mediated by the DEAD Box (DDX)-5/17 RNA Helicases.	CKAP5 SIPA1L1 DHX9 CLTC	3.30e-04	295	39	4	26209609
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	CKAP5 ABCB7 NDUFS1 VPS50 CLTC	3.89e-04	560	39	5	35241646
Pubmed	Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation.	CPSF2 NDUFS1 DHX9	4.13e-04	129	39	3	28973437
Pubmed	TRAIP regulates replication fork recovery and progression via PCNA.	FANCD2 MCMBP	4.23e-04	27	39	2	27462463
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	CKAP5 NRXN1 SIPA1L1	4.23e-04	130	39	3	12421765
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	BRCC3 MCMBP ABCB7 CPSF2 NDUFS1 DHX9 CLTC	4.42e-04	1257	39	7	37317656
Pubmed	Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.	NRXN3 NRXN1	4.55e-04	28	39	2	38324473
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	CKAP5 CPSF2 HNRNPLL CLTC	5.15e-04	332	39	4	32786267
Pubmed	A genome-wide association study of behavioral disinhibition.	LRTM2 NRXN1	5.23e-04	30	39	2	23942779
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	WDR35 CPSF2 NDUFS1 SIPA1L1 DHX9 CLTC	5.28e-04	922	39	6	27609421
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	SRP54 ECEL1 ABCB7 LANCL2 NDUFS1 DHX9 CLTC	5.33e-04	1297	39	7	33545068
Pubmed	Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.	CKAP5 ECEL1 NDUFS1 DHX9 CLTC	5.87e-04	613	39	5	22268729
Pubmed	Gene-smoking interactions identify several novel blood pressure loci in the Framingham Heart Study.	FRY NRXN3	5.95e-04	32	39	2	25189868
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	FANCD2 TRAPPC13 ECEL1 ABCB7 NDUFS1 SLC39A8 CLTC	6.11e-04	1327	39	7	32694731
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	LANCL2 NDUFS1 SIPA1L1 RASAL1 DHX9	6.23e-04	621	39	5	22794259
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	CKAP5 FRYL DHX9	7.19e-04	156	39	3	22952844
GeneFamily	Solute carriers	SLC5A12 SLC44A4 SLC31A1 SLC39A8	1.00e-03	395	21	4	752
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CKAP5 FRYL NDUFS1 CLTC EFR3A	7.05e-07	193	39	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
Disease	systolic blood pressure, cigarettes per day measurement	FRY NRXN3	1.25e-04	13	38	2	EFO_0006335, EFO_0006525
Disease	Manganese Poisoning	SLC31A1 SLC39A8	1.46e-04	14	38	2	C0677050
Disease	social interaction measurement	NRXN1 GNRHR SIPA1L1	2.44e-04	94	38	3	EFO_0009592
Disease	caudate volume change measurement, age at assessment	NRXN3 NRXN1	5.55e-04	27	38	2	EFO_0008007, EFO_0021491
Disease	nicotine use, generational effect measurement, illegal drug consumption, non-substance related disinhibited behaviour, alcohol drinking, alcohol dependence	LRTM2 NRXN1	6.41e-04	29	38	2	EFO_0004329, EFO_0005430, EFO_0005431, EFO_0005432, EFO_0008364, MONDO_0007079
Disease	Mental Retardation, Psychosocial	FRY NRXN1 SLC31A1	7.65e-04	139	38	3	C0025363
Disease	Profound Mental Retardation	FRY NRXN1 SLC31A1	7.65e-04	139	38	3	C0020796
Disease	Mental deficiency	FRY NRXN1 SLC31A1	7.65e-04	139	38	3	C0917816
Disease	pack-years measurement, systolic blood pressure	FRY NRXN3	8.83e-04	34	38	2	EFO_0006335, EFO_0006526
Disease	autism spectrum disorder (implicated_via_orthology)	NRXN3 NRXN1 ITPR3	9.91e-04	152	38	3	DOID:0060041 (implicated_via_orthology)
Disease	triacylglycerol 50:3 measurement	LRTM2 ABCB7	1.16e-03	39	38	2	EFO_0010410

Protein segments in the cluster

Peptide	Gene	Start	Entry
ATIPVYKMGQMFMYD	CPSF2	86	Q9P2I0
TQKKPYSGFNMMMII	ANKK1	221	Q8NFD2
YQRSEIMMFIMGKVP	EFR3A	396	Q14156
MEQFMKLVGMPYLHE	RASAL1	351	O95294
LEKFGTICYVMMMPF	HNRNPLL	96	Q8WVV9
TFIRGYKAMVMDMEF	ITPR3	2306	Q14573
MYFMAPLQEKVVFGM	ADIPOR1	161	Q96A54
MAGIYYMLMQPAAKV	LANCL2	266	Q9NS86
MDTDKMAPVFYTMVI	OR5B3	266	Q8NH48
MDDFKTMFPNMDYDI	CUEDC1	51	Q9NWM3
SLIMGMKFFRVKMYP	FRYL	221	O94915
LSYDGSMYMKIIMPM	NRXN3	686	Q9Y4C0
YDGSMFMKIQLPVVM	NRXN1	721	Q9ULB1
AKLQYMMVMVGYPDF	ECEL1	501	O95672
MSPDFTVFMIKYLMT	FZD1	596	Q9UP38
ALPFFMMHLGYEKMA	CKAP5	1041	Q14008
MCLVYPASKMFPFIM	CKAP5	1316	Q14008
KLFSMYAPAFMMVVI	GNRHR	121	P30968
KAVGQMMSTMFYPLV	SLC44A4	346	Q53GD3
IMGMKFFRIKMYPVE	FRY	271	Q5TBA9
HAFVMIFFMVMPIMI	MT-CO1	61	P00395
MMMPMTFYFGFKNVE	SLC31A1	41	O15431
EPRFGKMMIMGCIFY	DHX9	861	Q08211
AMMMNAVFVKGILDY	FANCD2	506	Q9BXW9
MIQDMFDPEFYMGVY	MCMBP	71	Q9BTE3
LGMEFMEPMEKSIFY	TMEM67	906	Q5HYA8
DMYEQFQNIMKMGPF	SRP54	331	P61011
GKDMRMVPMEMFNYC	LRTM2	236	Q8N967
GNDMQVGTYIEKMFM	NDUFS1	201	P28331
YRMPVMEYKMNEGVS	SIPA1L1	1041	O43166
KAMNIVVPFMFKYAV	ABCB7	151	O75027
MYQMMDQGFVGLIFS	BRCC3	141	P46736
MMYVVFKEVPMMVPA	B3GALT9	256	A8MXE2
IMDFAMPYFIQVMKE	CLTC	1591	Q00610
YMQMMNILKPIAFDV	VPS50	621	Q96JG6
GYMEPYEAQKMMAEI	SHF	136	Q7M4L6
GMFLYISLADMFPEM	SLC39A8	401	Q9C0K1
DQLMPYFVMEIFATM	SLC5A12	316	Q1EHB4
PDLFAMMEKTRMYVF	WDR35	606	Q9P2L0
MFMEKVSLEPSIMYN	TRAPPC13	206	A5PLN9
IGMNFYMEIAKMRAG	MMUT	311	P22033