Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK2 AGAP5 TRIO RASGRF2 DOCK10 GBP2 KRIT1 NF1 RIC8A AGAP7P AGAP4 AGAP6 TNS3	6.91e-05	507	142	13	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK2 AGAP5 TRIO RASGRF2 DOCK10 GBP2 KRIT1 NF1 RIC8A AGAP7P AGAP4 AGAP6 TNS3	6.91e-05	507	142	13	GO:0030695
GeneOntologyMolecularFunction	phospholipid binding	SESTD1 AGAP5 AMPH GPAA1 SYT12 SYT10 KRIT1 NF1 AP2A2 PIK3C2G AGAP7P AGAP4 AGAP6	1.50e-04	548	142	13	GO:0005543
GeneOntologyMolecularFunction	enzyme regulator activity	DOCK2 PPP4R1 AGAP5 TRIO RASGRF2 CD109 DOCK10 GBP2 KRIT1 CCNT1 ANOS1 PPP2R5C NF1 PHACTR3 ETAA1 SPDYA TAOK1 RIC8A AGAP7P PZP AGAP4 AGAP6 TNS3	1.66e-04	1418	142	23	GO:0030234
GeneOntologyMolecularFunction	structural constituent of skin epidermis	KRT4 KRT6A KRT6B KRT6C	2.44e-04	43	142	4	GO:0030280
GeneOntologyBiologicalProcess	synaptic signaling	GABRD TSHZ3 AMPH SYT12 TRIO RASGRF2 RTN4 CLSTN1 SYT10 SLC12A5 ORAI1 NF1 STXBP3 PTPRS DLG2 PLA2G6 GRIN3A TNR EPHA7	4.57e-05	976	143	19	GO:0099536
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	GABRD TSHZ3 AMPH SYT12 TRIO RASGRF2 RTN4 CLSTN1 SYT10 SLC12A5 NF1 STXBP3 PTPRS DLG2 PLA2G6 GRIN3A TNR EPHA7	8.04e-05	931	143	18	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	GABRD TSHZ3 AMPH SYT12 TRIO RASGRF2 RTN4 CLSTN1 SYT10 SLC12A5 NF1 STXBP3 PTPRS DLG2 PLA2G6 GRIN3A TNR EPHA7	8.04e-05	931	143	18	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	GABRD TSHZ3 AMPH SYT12 TRIO RASGRF2 RTN4 CLSTN1 SYT10 SLC12A5 NF1 STXBP3 PTPRS DLG2 PLA2G6 GRIN3A TNR EPHA7	8.95e-05	939	143	18	GO:0099537
GeneOntologyBiologicalProcess	regulation of Rac protein signal transduction	DOCK2 RTN4 NF1 TNS3	9.81e-05	35	143	4	GO:0035020
GeneOntologyCellularComponent	glutamatergic synapse	GABRD AMPH TRIO RASGRF2 RTN4 DOCK10 CLSTN1 SYT10 NF1 AP2A1 PIK3C3 PTPRS DLG2 GRIN3A TNR EPHA7	1.53e-04	817	143	16	GO:0098978
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	MMRN1 NID1 TNR	1.99e-04	17	143	3	GO:0098637
MousePheno	persistence of hyaloid vascular system	AGAP5 ALG11 CLSTN1 CCNT1 VCAN RIC8A AGAP7P AGAP4 AGAP6 DNASE1L2	1.29e-05	223	113	10	MP:0001289
MousePheno	fused cornea and lens	AGAP5 AGAP7P AGAP4 AGAP6	3.80e-05	24	113	4	MP:0001307
MousePheno	abnormal astrocyte physiology	DOCK10 CP NF1 PLA2G6	6.15e-05	27	113	4	MP:0008916
MousePheno	absent pinna reflex	WBP2 AGAP5 AP2A2 AGAP7P AGAP4 AGAP6	8.23e-05	89	113	6	MP:0006358
Domain	ARM-like	DOCK2 PPP4R1 DOCK10 XPO4 HUWE1 AP4E1 PPP2R5C KATNBL1 NF1 AP2A1 AP2A2 RIC8A	9.22e-07	270	140	12	IPR011989
Domain	ARM-type_fold	DOCK2 PPP4R1 XPO4 HUWE1 AP4E1 PPP2R5C NF1 AP2A1 AP2A2 PIK3C2G PIK3C3 RIC8A TAF2	1.67e-06	339	140	13	IPR016024
Domain	PH_dom-like	WBP2 AGAP5 TRIO RASGRF2 MYO7B DOCK10 NIBAN2 PTPN3 DGKK AGAP7P AGAP4 AGAP6 TNS3	1.96e-05	426	140	13	IPR011993
Domain	Coatomer/calthrin_app_sub_C	AP4E1 AP2A1 AP2A2	2.25e-05	8	140	3	IPR009028
Domain	-	WBP2 AGAP5 TRIO RASGRF2 MYO7B DOCK10 NIBAN2 PTPN3 DGKK AGAP4 AGAP6 TNS3	3.93e-05	391	140	12	2.30.29.30
Domain	Keratin_II	KRT4 KRT6A KRT6B KRT6C	3.98e-05	26	140	4	IPR003054
Domain	CRAL_TRIO	SESTD1 TRIO NF1 SEC14L5	4.64e-05	27	140	4	PS50191
Domain	CRAL-TRIO_dom	SESTD1 TRIO NF1 SEC14L5	5.38e-05	28	140	4	IPR001251
Domain	-	AP2A1 AP2A2	5.58e-05	2	140	2	2.60.40.1030
Domain	Ribosomal_L10e_CS	RPL10L RPL10	5.58e-05	2	140	2	IPR018255
Domain	Clathrin_a-adaptin_app_Ig-like	AP2A1 AP2A2	5.58e-05	2	140	2	IPR013038
Domain	AP2_complex_asu	AP2A1 AP2A2	5.58e-05	2	140	2	IPR017104
Domain	Clathrin_a-adaptin_app_sub_C	AP2A1 AP2A2	5.58e-05	2	140	2	IPR003164
Domain	Ribosomal_L10e	RPL10L RPL10	5.58e-05	2	140	2	IPR001197
Domain	Alpha_adaptin_C	AP2A1 AP2A2	5.58e-05	2	140	2	PF02296
Domain	RIBOSOMAL_L10E	RPL10L RPL10	5.58e-05	2	140	2	PS01257
Domain	ArfGap	AGAP5 AGAP7P AGAP4 AGAP6	6.21e-05	29	140	4	SM00105
Domain	ARFGAP	AGAP5 AGAP7P AGAP4 AGAP6	6.21e-05	29	140	4	PS50115
Domain	ArfGap	AGAP5 AGAP7P AGAP4 AGAP6	6.21e-05	29	140	4	PF01412
Domain	ArfGAP	AGAP5 AGAP7P AGAP4 AGAP6	6.21e-05	29	140	4	IPR001164
Domain	Teashirt_fam	TSHZ3 TSHZ2	1.67e-04	3	140	2	IPR027008
Domain	Ribosomal_L10e/L16	RPL10L RPL10	1.67e-04	3	140	2	IPR016180
Domain	-	RPL10L RPL10	1.67e-04	3	140	2	3.90.1170.10
Domain	Ribosomal_L16	RPL10L RPL10	1.67e-04	3	140	2	PF00252
Domain	Clathrin/coatomer_adapt-like_N	AP4E1 AP2A1 AP2A2	1.76e-04	15	140	3	IPR002553
Domain	Adaptin_N	AP4E1 AP2A1 AP2A2	1.76e-04	15	140	3	PF01602
Domain	PH	AGAP5 TRIO RASGRF2 DOCK10 NIBAN2 DGKK AGAP7P AGAP4 AGAP6	2.52e-04	278	140	9	SM00233
Domain	PH_DOMAIN	AGAP5 TRIO RASGRF2 DOCK10 NIBAN2 DGKK AGAP7P AGAP4 AGAP6	2.59e-04	279	140	9	PS50003
Domain	PH_domain	AGAP5 TRIO RASGRF2 DOCK10 NIBAN2 DGKK AGAP7P AGAP4 AGAP6	2.66e-04	280	140	9	IPR001849
Domain	-	PPP4R1 XPO4 AP4E1 PPP2R5C NF1 AP2A1 AP2A2 RIC8A	2.74e-04	222	140	8	1.25.10.10
Domain	Clathrin_a/coatomer_app_sub_C	AP2A1 AP2A2	3.31e-04	4	140	2	IPR015873
Domain	-	AP2A1 AP2A2	3.31e-04	4	140	2	3.30.310.30
Domain	FN3	FLNC SPEG ANOS1 PTPRS TNR USH2A EPHA7	4.96e-04	185	140	7	SM00060
Domain	ANK_REPEAT	AGAP5 MUC16 KRIT1 PLA2G6 POTEA AGAP7P AGAP4 AGAP6	6.52e-04	253	140	8	PS50088
Domain	ANK_REP_REGION	AGAP5 MUC16 KRIT1 PLA2G6 POTEA AGAP7P AGAP4 AGAP6	6.69e-04	254	140	8	PS50297
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	7.43e-04	24	140	3	IPR032444
Domain	Keratin_2_head	KRT6A KRT6B KRT6C	7.43e-04	24	140	3	PF16208
Domain	SEC14	TRIO NF1 SEC14L5	8.40e-04	25	140	3	SM00516
Domain	FN3_dom	FLNC SPEG ANOS1 PTPRS TNR USH2A EPHA7	1.02e-03	209	140	7	IPR003961
Domain	Intermediate_filament_CS	KRT4 KRT6A KRT6B KRT6C	1.28e-03	63	140	4	IPR018039
Domain	fn3	SPEG ANOS1 PTPRS TNR USH2A EPHA7	1.40e-03	162	140	6	PF00041
Domain	C2_dom	SYT12 SYT10 C2CD2 PIK3C2G PIK3C3 TNS3	1.49e-03	164	140	6	IPR000008
Domain	-	CPA1 CPA2	1.52e-03	8	140	2	3.30.70.340
Domain	Sec1-like	SCFD2 STXBP3	1.52e-03	8	140	2	IPR001619
Domain	Sec-1-like_dom2	SCFD2 STXBP3	1.52e-03	8	140	2	IPR027482
Domain	PI3K_C2	PIK3C2G PIK3C3	1.52e-03	8	140	2	SM00142
Domain	PI3K_C2_dom	PIK3C2G PIK3C3	1.52e-03	8	140	2	IPR002420
Domain	Sec1	SCFD2 STXBP3	1.52e-03	8	140	2	PF00995
Domain	-	SCFD2 STXBP3	1.52e-03	8	140	2	3.40.50.1910
Domain	PI3K_C2	PIK3C2G PIK3C3	1.52e-03	8	140	2	PF00792
Domain	Propep_M14	CPA1 CPA2	1.52e-03	8	140	2	PF02244
Domain	PI3K_C2	PIK3C2G PIK3C3	1.52e-03	8	140	2	PS51547
Domain	M14A_act_pep	CPA1 CPA2	1.52e-03	8	140	2	IPR003146
Domain	SPEC	SESTD1 TRIO MACF1	1.74e-03	32	140	3	SM00150
Domain	Spectrin/alpha-actinin	SESTD1 TRIO MACF1	1.74e-03	32	140	3	IPR018159
Domain	PI3Ka	PIK3C2G PIK3C3	1.94e-03	9	140	2	PF00613
Domain	Alpha_adaptinC2	AP2A1 AP2A2	1.94e-03	9	140	2	PF02883
Domain	PI3Ka	PIK3C2G PIK3C3	1.94e-03	9	140	2	SM00145
Domain	Clathrin_a/b/g-adaptin_app_Ig	AP2A1 AP2A2	1.94e-03	9	140	2	IPR008152
Domain	Alpha_adaptinC2	AP2A1 AP2A2	1.94e-03	9	140	2	SM00809
Domain	-	PIK3C2G PIK3C3	1.94e-03	9	140	2	1.25.40.70
Domain	IF	KRT4 KRT6A KRT6B KRT6C	2.10e-03	72	140	4	PS00226
Domain	Filament	KRT4 KRT6A KRT6B KRT6C	2.21e-03	73	140	4	PF00038
Domain	A2M	CD109 PZP	2.41e-03	10	140	2	PF00207
Domain	A2M_N_2	CD109 PZP	2.41e-03	10	140	2	IPR011625
Domain	A2M_comp	CD109 PZP	2.41e-03	10	140	2	IPR011626
Domain	A2M_recep	CD109 PZP	2.41e-03	10	140	2	PF07677
Domain	A2M_comp	CD109 PZP	2.41e-03	10	140	2	PF07678
Domain	PI_Kinase	PIK3C2G PIK3C3	2.41e-03	10	140	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3C2G PIK3C3	2.41e-03	10	140	2	IPR001263
Domain	A2M_N	CD109 PZP	2.41e-03	10	140	2	PF01835
Domain	A2M_N	CD109 PZP	2.41e-03	10	140	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	CD109 PZP	2.41e-03	10	140	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	CD109 PZP	2.41e-03	10	140	2	PS00477
Domain	A2M_N_2	CD109 PZP	2.41e-03	10	140	2	PF07703
Domain	PIK_HELICAL	PIK3C2G PIK3C3	2.41e-03	10	140	2	PS51545
Domain	Macroglobln_a2	CD109 PZP	2.41e-03	10	140	2	IPR001599
Domain	IF	KRT4 KRT6A KRT6B KRT6C	2.56e-03	76	140	4	IPR001664
Domain	ANK	AGAP5 KRIT1 PLA2G6 POTEA AGAP7P AGAP4 AGAP6	2.88e-03	251	140	7	SM00248
Domain	DHR-1_domain	DOCK2 DOCK10	2.94e-03	11	140	2	IPR027007
Domain	DHR_2	DOCK2 DOCK10	2.94e-03	11	140	2	PS51651
Domain	DHR_1	DOCK2 DOCK10	2.94e-03	11	140	2	PS51650
Domain	DHR-2	DOCK2 DOCK10	2.94e-03	11	140	2	PF06920
Domain	DOCK	DOCK2 DOCK10	2.94e-03	11	140	2	IPR026791
Domain	DOCK_C	DOCK2 DOCK10	2.94e-03	11	140	2	IPR010703
Domain	DOCK-C2	DOCK2 DOCK10	2.94e-03	11	140	2	PF14429
Domain	DHR-2	DOCK2 DOCK10	2.94e-03	11	140	2	IPR027357
Domain	Ankyrin_rpt-contain_dom	AGAP5 KRIT1 PLA2G6 POTEA AGAP7P AGAP4 AGAP6	3.07e-03	254	140	7	IPR020683
Domain	CRAL_TRIO_2	SESTD1 NF1	3.51e-03	12	140	2	PF13716
Domain	Coatomer/clathrin_app_Ig-like	AP2A1 AP2A2	3.51e-03	12	140	2	IPR013041
Domain	Ankyrin_rpt	AGAP5 KRIT1 PLA2G6 POTEA AGAP7P AGAP4 AGAP6	3.65e-03	262	140	7	IPR002110
Domain	C2	SYT12 SYT10 C2CD2 PIK3C2G PIK3C3	3.73e-03	137	140	5	SM00239
Domain	FN3	SPEG ANOS1 PTPRS TNR USH2A EPHA7	3.91e-03	199	140	6	PS50853
Domain	SH3_2	DOCK2 AMPH MYO7B DLG2	3.99e-03	86	140	4	PF07653
Domain	SH3_2	DOCK2 AMPH MYO7B DLG2	3.99e-03	86	140	4	IPR011511
Domain	P_typ_ATPase_c	ATP9B ATP9A	4.79e-03	14	140	2	IPR032630
Domain	P-type_ATPase_N	ATP9B ATP9A	4.79e-03	14	140	2	IPR032631
Domain	P-type_ATPase_IV	ATP9B ATP9A	4.79e-03	14	140	2	IPR006539
Domain	PhoLip_ATPase_C	ATP9B ATP9A	4.79e-03	14	140	2	PF16212
Domain	PhoLip_ATPase_N	ATP9B ATP9A	4.79e-03	14	140	2	PF16209
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SESTD1 AGAP5 AMPH TRIO NF1 AP2A1 AP2A2 MACF1 DLG2 AGAP7P TNR AGAP4 AGAP6	2.51e-10	281	147	13	28706196
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP5 AGAP7P AGAP4 AGAP6	3.80e-08	9	147	4	12640130
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP5 AGAP7P AGAP4 AGAP6	6.31e-08	10	147	4	20664521
Pubmed	Genetic variants in pachyonychia congenita-associated keratins increase susceptibility to tooth decay.	KRT6A KRT6B KRT6C	7.40e-08	3	147	3	29357356
Pubmed	Cloning and characterization of multiple human genes and cDNAs encoding highly related type II keratin 6 isoforms.	KRT6A KRT6B KRT6C	7.40e-08	3	147	3	7543104
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP5 AGAP7P AGAP4 AGAP6	9.88e-08	11	147	4	15381706
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP5 AGAP7P AGAP4 AGAP6	2.13e-07	13	147	4	27713690
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP5 AGAP7P AGAP4 AGAP6	2.97e-07	14	147	4	22453919
Pubmed	Pachyonychia Congenita	KRT6A KRT6B KRT6C	7.35e-07	5	147	3	20301457
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	AGAP5 MCCC1 ATP9A NF1 VCAN MACF1 DLG2 AGAP7P TNR AGAP4 AGAP6	2.39e-06	430	147	11	32581705
Pubmed	Clathrin interacts specifically with amphiphysin and is displaced by dynamin.	AMPH AP2A1 AP2A2	2.56e-06	7	147	3	9280305
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	KRT6A FLNC KRT6B AMPH TRIO RTN4 SRP72 ATP9A SLC12A5 NF1 AP2A1 AP2A2 PTPRS VCAN GLUD1 MACF1 DLG2 TNR DHX29 RPL10	2.75e-06	1431	147	20	37142655
Pubmed	Decreased synaptic vesicle recycling efficiency and cognitive deficits in amphiphysin 1 knockout mice.	AMPH AP2A1 AP2A2	4.08e-06	8	147	3	11879655
Pubmed	RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.	KRT4 KRT6A KRT6B MCCC1 KRT6C	4.42e-06	57	147	5	31862882
Pubmed	Accessory protein recruitment motifs in clathrin-mediated endocytosis.	AMPH AP2A1 AP2A2	6.10e-06	9	147	3	12057195
Pubmed	FCH domain only-2 organizes clathrin-coated structures and interacts with Disabled-2 for low-density lipoprotein receptor endocytosis.	TRIO CCNT1 AP2A1 AP2A2	8.82e-06	31	147	4	22323290
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RPL10L MYH3 KRT6A FLNC KRT6B STRBP CCDC150 SRP72 OR13D1 AP2A1 AP2A2 KRT6C PMPCA DGKK GLUD1 MACF1 DLG2 ISG20L2 RPL10	1.15e-05	1442	147	19	35575683
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	WBP2 B4GALT7 GPAA1 RTN4 PCDHAC2 ALG11 HUWE1 C2CD2 CCNT1 ORAI1 NF1 STXBP3 AP2A1 PMPCA PTPRS MACF1	1.17e-05	1061	147	16	33845483
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	KRT6A FLNC STRBP ICE2 RTN4 NIBAN2 MCCC1 TFCP2 SYNJ2 MACF1 TAF2 DHX29 TNS3	1.34e-05	724	147	13	36232890
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	IFT140 AGAP5 SATB2 RTN4 XPO4 PPP2R5C SYNJ2 AGAP7P ZC3H7B AGAP4 AGAP6	1.67e-05	529	147	11	14621295
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	CARM1 FLNC RTN4 CD109 XPO4 HUWE1 PTPN3 AP2A1 PMPCA PTPRS GLUD1 NID1 DHX29 RPL10 TNS3	1.75e-05	974	147	15	28675297
Pubmed	Orai1 and Ca2+-independent phospholipase A2 are required for store-operated Icat-SOC current, Ca2+ entry, and proliferation of primary vascular smooth muscle cells.	ORAI1 PLA2G6	1.77e-05	2	147	2	22094335
Pubmed	A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos.	KRT6A KRT6B	1.77e-05	2	147	2	11118885
Pubmed	Resistance to inhibitors of cholinesterase (Ric)-8A and Gαi contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps)34 activity.	PIK3C3 RIC8A	1.77e-05	2	147	2	24466196
Pubmed	Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure.	FLNC TRIO	1.77e-05	2	147	2	16914736
Pubmed	Satb2 Regulates EphA7 to Control Soma Spacing and Self-Avoidance of Cortical Pyramidal Neurons.	SATB2 EPHA7	1.77e-05	2	147	2	34546353
Pubmed	Expression of MK6a dominant-negative and C-terminal mutant transgenes in mice has distinct phenotypic consequences in the epidermis and hair follicle.	KRT6A KRT6B	1.77e-05	2	147	2	10550543
Pubmed	The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis.	KRT6A KRT6B	1.77e-05	2	147	2	10550545
Pubmed	Changes in zinc ligation promote remodeling of the active site in the zinc hydrolase superfamily.	CPA1 CPA2	1.77e-05	2	147	2	11743734
Pubmed	The two functional keratin 6 genes of mouse are differentially regulated and evolved independently from their human orthologs.	KRT6A KRT6B	1.77e-05	2	147	2	9790766
Pubmed	Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.	TSHZ3 TSHZ2	1.77e-05	2	147	2	21423795
Pubmed	Collapse of the keratin filament network through the expression of mutant keratin 6c observed in a case of focal plantar keratoderma.	KRT6A KRT6C	1.77e-05	2	147	2	23662636
Pubmed	Cloning of cDNAs encoding two related 100-kD coated vesicle proteins (alpha-adaptins).	AP2A1 AP2A2	1.77e-05	2	147	2	2564002
Pubmed	Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b.	KRT6A KRT6B	1.77e-05	2	147	2	11489919
Pubmed	Delayed wound healing in keratin 6a knockout mice.	KRT6A KRT6B	1.77e-05	2	147	2	10866680
Pubmed	Introducing a null mutation in the mouse K6alpha and K6beta genes reveals their essential structural role in the oral mucosa.	KRT6A KRT6B	1.77e-05	2	147	2	10953016
Pubmed	The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins.	KRT6A KRT6B	1.77e-05	2	147	2	6207530
Pubmed	Cytokeratins mediate epithelial innate defense through their antimicrobial properties.	KRT6A KRT6B	1.77e-05	2	147	2	23006328
Pubmed	NKD2 mediates stimulation-dependent ORAI1 trafficking to augment Ca2+ entry in T cells.	ORAI1 NKD2	1.77e-05	2	147	2	34433025
Pubmed	Cloning, physical mapping and structural characterization of the human alpha(A)-adaptin gene.	AP2A1 AP2A2	1.77e-05	2	147	2	12036598
Pubmed	A Novel, Synthetic, Neuroactive Steroid Is Effective at Decreasing Depression-Like Behaviors and Improving Maternal Care in Preclinical Models of Postpartum Depression.	GABRD SLC12A5	1.77e-05	2	147	2	30532739
Pubmed	Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.	CPA1 CPA2	1.77e-05	2	147	2	8806703
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	WBP2 IFT140 AGAP5 MAN2B2 ALPK1 AP4E1 NF1 AP2A2 SYNJ2 OTUD6B DLG2 PLA2G6 AGAP7P AGAP4 AGAP6 DNASE1L2 PUS7L	2.13e-05	1242	147	17	30973865
Pubmed	Antagonistic functions of Dishevelleds regulate Frizzled3 endocytosis via filopodia tips in Wnt-mediated growth cone guidance.	AMPH AP2A1 AP2A2	3.98e-05	16	147	3	24305805
Pubmed	Hague (Hag). A new mouse hair mutation with an unstable semidominant allele.	KRT4 KRT6A KRT6B	3.98e-05	16	147	3	12399393
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	DOCK2 FLNC RTN4 CP NIBAN2 MCCC1 HUWE1 STXBP3 AP2A1 AP2A2 MACF1 HYDIN RPL10	4.13e-05	807	147	13	30575818
Pubmed	The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.	AGAP5 SRP72 HUWE1 PTPN3 ISG20L2 AGAP7P AGAP4	5.11e-05	225	147	7	25277244
Pubmed	Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development.	TSHZ3 TSHZ2	5.31e-05	3	147	2	16631416
Pubmed	Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles.	KRT6A KRT6B	5.31e-05	3	147	2	17170733
Pubmed	Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses.	AP2A1 AP2A2	5.31e-05	3	147	2	35014951
Pubmed	A diacidic motif in human immunodeficiency virus type 1 Nef is a novel determinant of binding to AP-2.	AP2A1 AP2A2	5.31e-05	3	147	2	18032517
Pubmed	AP2 adaptor complex mediates bile salt export pump internalization and modulates its hepatocanalicular expression and transport function.	AP2A1 AP2A2	5.31e-05	3	147	2	22262466
Pubmed	Overcoming functional redundancy to elicit pachyonychia congenita-like nail lesions in transgenic mice.	KRT6A KRT6B	5.31e-05	3	147	2	15601842
Pubmed	Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.	TSHZ3 TSHZ2	5.31e-05	3	147	2	19745106
Pubmed	Amphiphysin (Amph) maps to the proximal region of mouse chromosome 13.	AMPH NID1	5.31e-05	3	147	2	8530056
Pubmed	Envelope Glycoprotein Internalization Protects Human and Simian Immunodeficiency Virus-Infected Cells from Antibody-Dependent Cell-Mediated Cytotoxicity.	AP2A1 AP2A2	5.31e-05	3	147	2	26269175
Pubmed	Cytokeratin 5/6 expression in bladder cancer: association with clinicopathologic parameters and prognosis.	KRT6A KRT6B	5.31e-05	3	147	2	29587848
Pubmed	Genome-wide association study identifies nidogen 1 (NID1) as a susceptibility locus to cutaneous nevi and melanoma risk.	NID1 PLA2G6	5.31e-05	3	147	2	21478494
Pubmed	A role for keratins in supporting mitochondrial organization and function in skin keratinocytes.	KRT6A KRT6B	5.31e-05	3	147	2	32213122
Pubmed	A basic patch on alpha-adaptin is required for binding of human immunodeficiency virus type 1 Nef and cooperative assembly of a CD4-Nef-AP-2 complex.	AP2A1 AP2A2	5.31e-05	3	147	2	19129443
Pubmed	Interaction of Shc with adaptor protein adaptins.	AP2A1 AP2A2	5.31e-05	3	147	2	8617812
Pubmed	Overexpression of Orai1 and STIM1 proteins alters regulation of store-operated Ca2+ entry by endogenous mediators.	ORAI1 PLA2G6	5.31e-05	3	147	2	22549787
Pubmed	Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration.	ORAI1 PLA2G6	5.31e-05	3	147	2	23043102
Pubmed	Inhibition of receptor-mediated endocytosis by the amphiphysin SH3 domain.	AMPH AP2A1	5.31e-05	3	147	2	9259551
Pubmed	Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita.	KRT6A KRT6B	5.31e-05	3	147	2	17851587
Pubmed	A small deletion hotspot in the type II keratin gene mK6irs1/Krt2-6g on mouse chromosome 15, a candidate for causing the wavy hair of the caracul (Ca) mutation.	KRT6A KRT6B	5.31e-05	3	147	2	14573483
Pubmed	Loss of keratin 6 (K6) proteins reveals a function for intermediate filaments during wound repair.	KRT6A KRT6B	5.31e-05	3	147	2	14568992
Pubmed	The C-type lectin domains of lecticans, a family of aggregating chondroitin sulfate proteoglycans, bind tenascin-R by protein-protein interactions independent of carbohydrate moiety.	VCAN TNR	5.31e-05	3	147	2	9294172
Pubmed	Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing.	CPA1 CPA2	5.31e-05	3	147	2	20385563
Pubmed	Chymotrypsin C is a co-activator of human pancreatic procarboxypeptidases A1 and A2.	CPA1 CPA2	5.31e-05	3	147	2	21098023
Pubmed	Three putative murine Teashirt orthologues specify trunk structures in Drosophila in the same way as the Drosophila teashirt gene.	TSHZ3 TSHZ2	5.31e-05	3	147	2	14973285
Pubmed	Identification of a cloned sequence activated during multi-stage carcinogenesis in mouse skin.	KRT6A KRT6B	5.31e-05	3	147	2	1713533
Pubmed	The ear of alpha-adaptin interacts with the COOH-terminal domain of the Eps 15 protein.	AP2A1 AP2A2	5.31e-05	3	147	2	8662627
Pubmed	Reticulon 4 is necessary for endoplasmic reticulum tubulation, STIM1-Orai1 coupling, and store-operated calcium entry.	RTN4 ORAI1	5.31e-05	3	147	2	24558039
Pubmed	Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas.	TRIO NKD2	5.31e-05	3	147	2	16752383
Pubmed	Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.	AMPH AP2A1 AP2A2 VCAN GLUD1	5.94e-05	97	147	5	22360420
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	DOCK2 RPL10L TDRD15 FLNC KRT6B MUC16 SRP72 AP2A1 AP2A2 GLUD1 PHACTR3 MACF1 RPL10	6.50e-05	844	147	13	25963833
Pubmed	Ikaros promotes early-born neuronal fates in the cerebral cortex.	SATB2 IKZF3 IKZF5	6.82e-05	19	147	3	23382203
Pubmed	An investigation into the human serum "interactome".	KRT6A KRT6B CP AP4E1 MACF1 TNS3	6.85e-05	162	147	6	15174051
Pubmed	The B cell coreceptor CD22 associates with AP50, a clathrin-coated pit adapter protein, via tyrosine-dependent interaction.	AP2A1 AP2A2	1.06e-04	4	147	2	12646615
Pubmed	Keratin 6 regulates collective keratinocyte migration by altering cell-cell and cell-matrix adhesion.	KRT6A KRT6B	1.06e-04	4	147	2	30389720
Pubmed	Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade.	KRIT1 PIK3C3	1.06e-04	4	147	2	12925680
Pubmed	Disruption of the murine Ap2β1 gene causes nonsyndromic cleft palate.	AP2A1 AP2A2	1.06e-04	4	147	2	20500056
Pubmed	A review of the clinical phenotype of 254 patients with genetically confirmed pachyonychia congenita.	KRT6A KRT6B	1.06e-04	4	147	2	22264670
Pubmed	Mouse models in preclinical studies for pachyonychia congenita.	KRT6A KRT6B	1.06e-04	4	147	2	16250208
Pubmed	Phosphorylation of human keratin 8 in vivo at conserved head domain serine 23 and at epidermal growth factor-stimulated tail domain serine 431.	KRT6A KRT6C	1.06e-04	4	147	2	9054461
Pubmed	Association and colocalization of Eps15 with adaptor protein-2 and clathrin.	AP2A1 AP2A2	1.06e-04	4	147	2	9049247
Pubmed	The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation.	KRT6A KRT6B FMO5	1.23e-04	23	147	3	19494835
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	CPA1 CPA2 EPHA7	1.40e-04	24	147	3	16446123
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK2 RPL10L TRIO RASGRF2 DOCK10 FTSJ1 MCCC1 HUWE1 CCNT1 PPP2R5C AP2A1 AP2A2 GLUD1	1.46e-04	916	147	13	32203420
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	CARM1 SATB2 TRIO RTN4 HUWE1 AP2A1 MACF1 EPHA7	1.50e-04	358	147	8	32460013
Pubmed	New consensus nomenclature for mammalian keratins.	KRT4 KRT6A KRT6B KRT6C	1.50e-04	63	147	4	16831889
Pubmed	Airway hillocks are injury-resistant reservoirs of unique plastic stem cells.	KRT6A KRT6B	1.76e-04	5	147	2	38693267
Pubmed	Weak Molecular Interactions in Clathrin-Mediated Endocytosis.	AP2A1 AP2A2	1.76e-04	5	147	2	29184887
Pubmed	The proteoglycans aggrecan and Versican form networks with fibulin-2 through their lectin domain binding.	VCAN TNR	1.76e-04	5	147	2	11038354
Pubmed	Solo/Trio8, a membrane-associated short isoform of Trio, modulates endosome dynamics and neurite elongation.	SESTD1 TRIO	1.76e-04	5	147	2	16943433
Pubmed	A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein.	AP2A1 AP2A2	1.76e-04	5	147	2	17108326
Pubmed	Role for keratins 6 and 17 during wound closure in embryonic mouse skin.	KRT6A KRT6B	1.76e-04	5	147	2	12557214
Pubmed	Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.	AP2A1 AP2A2	1.76e-04	5	147	2	9723620
Pubmed	Purification and properties of five different forms of human procarboxypeptidases.	CPA1 CPA2	1.76e-04	5	147	2	2920728
Interaction	KRT26 interactions	KRT4 KRT6A KRT6B CCDC146 KRT6C	5.08e-06	35	146	5	int:KRT26
Interaction	KRT25 interactions	KRT4 KRT6A KRT6B TFCP2 KRT6C	5.08e-06	35	146	5	int:KRT25
Cytoband	12q13.13	KRT4 KRT6A KRT6B KRT6C	6.61e-05	67	147	4	12q13.13
GeneFamily	Keratins, type II	KRT4 KRT6A KRT6B KRT6C	1.19e-05	27	96	4	609
GeneFamily	ArfGAPs	AGAP5 AGAP7P AGAP4 AGAP6	2.71e-05	33	96	4	395
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP5 AGAP4 AGAP6	9.35e-05	17	96	3	1291
GeneFamily	Ankyrin repeat domain containing	AGAP5 KRIT1 PLA2G6 POTEA AGAP7P AGAP4 AGAP6	3.06e-04	242	96	7	403
GeneFamily	Phosphatidylinositol 3-kinase subunits	PIK3C2G PIK3C3	7.65e-04	8	96	2	831
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	AGAP5 RASGRF2 DOCK10 AGAP7P AGAP4 AGAP6	8.05e-04	206	96	6	682
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	CD109 PZP	9.80e-04	9	96	2	1234
GeneFamily	Fibronectin type III domain containing	ANOS1 PTPRS TNR USH2A EPHA7	1.63e-03	160	96	5	555
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	MYO7B KRIT1 PTPN3	2.37e-03	50	96	3	1293
GeneFamily	ATPase phospholipid transporting	ATP9B ATP9A	2.80e-03	15	96	2	1210
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	TSHZ3 TSHZ2	2.80e-03	15	96	2	529
GeneFamily	Cadherin related	DCHS2 CLSTN1	3.60e-03	17	96	2	24
GeneFamily	Synaptotagmins	SYT12 SYT10	3.60e-03	17	96	2	765
GeneFamily	Carboxypeptidases	CPA1 CPA2	5.49e-03	21	96	2	1321
Coexpression	THEODOROU_MAMMARY_TUMORIGENESIS	AGAP5 NKD2 AGAP7P AGAP4 AGAP6	1.83e-06	37	145	5	MM1121
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	TSHZ3 TSHZ2 OLFML2A NKD2 PTPRS PHACTR3 NID1 TOX2	2.52e-07	193	146	8	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Bronchus_Control_(B.)\|World / Sample group, Lineage and Cell type	KRT6A KRT6B TSHZ2 MUC16 CP PRDM2 SYNJ2 SHOC1	2.95e-07	197	146	8	b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT4 DNAH3 CCDC146 TSHZ2 STRBP MUC16 CP HYDIN	3.06e-07	198	146	8	d0ecace1fad24ce50b0935036fabb07e6c9e372d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 KCNT2 DLG2 DHRSX HYDIN TNS3 EPHA7	2.30e-06	181	146	7	6956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GLYAT DCHS2 SATB2 FMO5 MYO7B USH2A EPHA7	2.47e-06	183	146	7	d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B PIK3C2G DGKK PHACTR3 USH2A HYDIN EPHA7	2.56e-06	184	146	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B PIK3C2G DGKK PHACTR3 USH2A HYDIN EPHA7	2.56e-06	184	146	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO7B PIK3C2G DGKK PHACTR3 USH2A HYDIN EPHA7	2.56e-06	184	146	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	IKZF3 DOCK10 HUWE1 PRDM2 NF1 MACF1 TAOK1	2.96e-06	188	146	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Kidney-nan-3m-Epithelial-Epcam____podocyte-2\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SATB2 TSHZ2 CP NIBAN2 SPDYA TNS3 EPHA7	2.96e-06	188	146	7	c300accbac71a3bc075fe985543d8a8ead82531b
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT4 KRT6A KRT6B SYT12 MUC16 CP KRT6C	2.96e-06	188	146	7	07705bed928683470a52c8ccfa40ffb9a0971318
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT4 KRT6A HUWE1 AP2A2 PTPRS GLUD1 TAOK1	3.17e-06	190	146	7	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT6B TSHZ2 MUC16 CP SYNJ2 CYP4X1 DMBT1	3.28e-06	191	146	7	30e7cc5f7eadf90ab0900a73fdfe48f9a1adcbfb
ToppCell	cellseq-Epithelial-Epithelial_Glandular-SMG_Basal/Duct-SMG_Basal/Duct\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT6B TSHZ2 MUC16 CP SYNJ2 CYP4X1 DMBT1	3.28e-06	191	146	7	41d2f5278f6d5f52a5bdf4f3df70969481c00162
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6B TSHZ2 MUC16 CP SYNJ2 CYP4X1 DMBT1	3.40e-06	192	146	7	c227ab1914191e839fc39c9adc2080026d4b04fc
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6B TSHZ2 MUC16 CP SYNJ2 CYP4X1 DMBT1	3.40e-06	192	146	7	bf187a57a559ab732bb815892af45ca922966ac6
ToppCell	3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT6B TSHZ2 MUC16 CP SYNJ2 CYP4X1 DMBT1	3.40e-06	192	146	7	f573b2d205bd4d053a548af3fe3ff9de7be0cd2b
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	SESTD1 TSHZ2 KCNT2 PTPRS VCAN CYP4X1 NID1	3.40e-06	192	146	7	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TSHZ3 TSHZ2 OLFML2A NKD2 VCAN PHACTR3 TOX2	3.64e-06	194	146	7	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SCFD2 TSHZ3 TSHZ2 DOCK10 VCAN CCDC68 MACF1	3.64e-06	194	146	7	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT4 KRT6A DNAH3 MUC16 CP CLSTN1 HYDIN	4.02e-06	197	146	7	5c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ3 RASGRF2 BEND4 NR1I2 KCNT2 PIK3C2G NID1	4.02e-06	197	146	7	ee8f7def9d5af7b1e636830a4ea1da158d02f25a
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC TSHZ2 MMRN1 OLFML2A PTPN3 PIK3C2G NID1	4.30e-06	199	146	7	1587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FLNC TSHZ2 MMRN1 OLFML2A PTPN3 PIK3C2G NID1	4.30e-06	199	146	7	a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT6B TSHZ2 CP PTPN3 SYNJ2 CYP4X1 DMBT1	4.30e-06	199	146	7	527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABRD AMPH PCDHAC2 SYT10 SLC12A5 CYP4X1 EPHA7	4.44e-06	200	146	7	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABRD AMPH PCDHAC2 SYT10 SLC12A5 CYP4X1 EPHA7	4.44e-06	200	146	7	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABRD AMPH PCDHAC2 SYT10 SLC12A5 CYP4X1 EPHA7	4.44e-06	200	146	7	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AMPH CP VCAN PHACTR3 MACF1 TNS3	1.53e-05	161	146	6	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	Ciliated_cells-B-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 CCDC146 MUC16 CFAP206 PZP HYDIN	1.70e-05	164	146	6	0e9961acbb1d6c0089e6805ba6756736fa4d8bed
ToppCell	Bronchial_Biopsy-Immune-T_and_NK\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	CCDC150 MMRN1 FSIP2 CCDC68 DLG2 TOX2	1.95e-05	168	146	6	435b2f238fbb3f50427e8cdecf2220615015153c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CP KCNT2 NKD2 VCAN NID1 EPHA7	2.02e-05	169	146	6	c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCell	COVID-19-kidney-Bcells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 TDRD15 IKZF3 STRBP DOCK10 BEND4	2.16e-05	171	146	6	8e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TDRD15 CP NR1I2 KCNT2 PIK3C2G PZP	2.54e-05	176	146	6	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC146 ALPK1 SYT10 PIK3C2G CFAP206 HYDIN	2.62e-05	177	146	6	e8bb4f8ecd5e283efec966b9fc2040a6152d5551
ToppCell	COVID-19-B_cells-Activated_B_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK2 IKZF3 STRBP BEND4 PRDM2 TNR	2.62e-05	177	146	6	653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 TSHZ2 SYT10 HYDIN TNS3 EPHA7	2.62e-05	177	146	6	da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SATB2 SYT10 DHRSX HYDIN TNS3 EPHA7	3.06e-05	182	146	6	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	TRIO TSHZ2 KCNT2 VCAN PHACTR3 MACF1	3.25e-05	184	146	6	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	droplet-Liver-LIVER_HEP-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF2 TSHZ2 BEND4 SYNJ2 ZC3H7B PUS7L	3.35e-05	185	146	6	bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCell	COVID-19-lung-B_cells\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 IKZF3 STRBP DOCK10 BEND4 PRDM2	3.35e-05	185	146	6	e8f1ad580f19705b5ca1d7d8867b2125f4891684
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	SESTD1 TRIO STRBP PELI1 PRDM2 TNS3	3.56e-05	187	146	6	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	facs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C3orf38 SPEG OLFML2A ADRA2B CCDC68 SPDYA	3.56e-05	187	146	6	f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCell	facs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C3orf38 SPEG OLFML2A ADRA2B CCDC68 SPDYA	3.56e-05	187	146	6	3ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	SESTD1 TRIO STRBP PELI1 PRDM2 TNS3	3.56e-05	187	146	6	af1327559f7e01bec070881cae52834917c3da65
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	TSHZ3 PTPRS VCAN MACF1 NID1 TNS3	3.67e-05	188	146	6	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRD DOCK10 ANOS1 VCAN GRIN3A TOX2	3.78e-05	189	146	6	979b7fa947538aa7ca4a219263da2575869a2caa
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 TRIO CP PHACTR3 SPDYA FAM135A	3.78e-05	189	146	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SESTD1 TRIO CP PHACTR3 SPDYA FAM135A	3.78e-05	189	146	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	COPD-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	SESTD1 TRIO STRBP PELI1 PRDM2 TNS3	3.89e-05	190	146	6	1e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TSHZ3 TSHZ2 NKD2 SYNJ2 VCAN TOX2	4.01e-05	191	146	6	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.01e-05	191	146	6	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	IKZF3 DOCK10 XPO4 HUWE1 CCNT1 MACF1	4.01e-05	191	146	6	9454f642c3621370fa23640b631301346b300950
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AMPH SPEG SYT10 KCNT2 NID1 PZP	4.01e-05	191	146	6	7853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCell	PND07-Epithelial-Epithelial_Airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT4 KRT6A DNAH3 CCDC146 SYT10 CFAP206	4.01e-05	191	146	6	b55500eb416f4f339031acad16b2737e5b891d8e
ToppCell	COVID-19_Mild-dn_T\|COVID-19_Mild / Disease condition and Cell class	SESTD1 PCDHAC2 CPA1 PTPN3 NKD2	4.03e-05	116	146	5	79c918f3bebfd5e0b865d2c7673af9ee3bc48779
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRD DOCK10 ANOS1 VCAN GRIN3A TOX2	4.13e-05	192	146	6	63d1b3efe93e5ff939278ebe40bacb38218ea09b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRD DOCK10 ANOS1 VCAN GRIN3A TOX2	4.13e-05	192	146	6	bd3fa6c8fcb618db64d11f25cabaf08608957c35
ToppCell	COPD-Epithelial-Goblet\|COPD / Disease state, Lineage and Cell class	KRT4 KRT6A MUC16 CP PTPN3 CYP4X1	4.13e-05	192	146	6	93b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.13e-05	192	146	6	0afb9dbe468e0be442c326e11c5fc0f699b32f23
ToppCell	facs-Aorta-Heart-3m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC PTPRS VCAN RPL10 TNS3 EPHA7	4.13e-05	192	146	6	0dc1f46e40346ed0b286e53b106a812441575100
ToppCell	COVID-19_Mild-Lymphoid_T/NK-dn_T\|COVID-19_Mild / Disease group, lineage and cell class	IKZF3 PCDHAC2 CPA1 PTPN3 NKD2	4.20e-05	117	146	5	9d417dd137c27f8fe9e57842cd5515fdc2f2dc06
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF3 PCDHAC2 CPA1 PTPN3 NKD2	4.20e-05	117	146	5	e74dd01ccb6cc630759146655fccec359f725b1d
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IKZF3 PCDHAC2 CPA1 PTPN3 NKD2	4.20e-05	117	146	5	3c67e8a184b5a8302cba584e5ee97006f6cd267f
ToppCell	LAM-Endothelial-LymEndo\|LAM / Condition, Lineage and Cell class	GABRD FLNC TSHZ2 MMRN1 OLFML2A NID1	4.25e-05	193	146	6	68eadc91c2d89edd2412e86dfe134dd7c0ef6ee9
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.25e-05	193	146	6	8d05805295c5d3aa93aeb38be5fbefa81e1be1f0
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	SESTD1 TSHZ2 KCNT2 PTPRS VCAN NID1	4.25e-05	193	146	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	Control-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	NKD2 PHACTR3 CCDC68 MACF1 TOX2 TNS3	4.25e-05	193	146	6	5896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	SESTD1 TSHZ2 KCNT2 PTPRS VCAN NID1	4.37e-05	194	146	6	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IKZF3 PCDHAC2 CPA1 PTPN3 NKD2	4.38e-05	118	146	5	d95344ef24a1a838232186c02725f556c5fd51ac
ToppCell	PBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IKZF3 PCDHAC2 CPA1 PTPN3 NKD2	4.38e-05	118	146	5	c234ea1969726356ee47d9364b716044cfbd125a
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.50e-05	195	146	6	1c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	SESTD1 AMPH TSHZ2 KCNT2 VCAN NID1	4.50e-05	195	146	6	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	PND10-Mesenchymal-Mesenchymal_structural\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.50e-05	195	146	6	11d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSHZ3 TSHZ2 DOCK10 VCAN CCDC68 MACF1	4.50e-05	195	146	6	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	COVID-19-Fibroblasts-Alveolar_FB\|COVID-19 / group, cell type (main and fine annotations)	NKD2 PTPRS PHACTR3 NID1 DLG2 TOX2	4.50e-05	195	146	6	603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	SESTD1 TSHZ2 KCNT2 PTPRS VCAN NID1	4.50e-05	195	146	6	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	SESTD1 TSHZ2 KCNT2 PTPRS VCAN NID1	4.50e-05	195	146	6	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRD DOCK10 ANOS1 VCAN GRIN3A TOX2	4.50e-05	195	146	6	98ca9f3aa36211dde1e6f7f3817b9418c95e583e
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHAC2 CLSTN1 OLFML2A CCDC68 TOX2 TNS3	4.50e-05	195	146	6	cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.50e-05	195	146	6	1f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AMPH CP VCAN PHACTR3 MACF1 TNS3	4.50e-05	195	146	6	10f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	KRT4 KRT6A KRT6B MUC16 CP CCDC68	4.63e-05	196	146	6	b246e482f012dd9782b49c2a953acedfa3c1139d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	KRT4 KRT6A KRT6B MUC16 CP CCDC68	4.63e-05	196	146	6	808c0a7d1889a8f3508ed9790c6dc7ec16bbc840
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNC OLFML2A PTPRS VCAN RPL10 TNS3	4.63e-05	196	146	6	2029f58ce6a7b8c35d3a7496c3341391990909ce
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-leukocyte\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	KRT4 KRT6A KRT6B IKZF3 TSHZ2 KRT6C	4.76e-05	197	146	6	d968d7d5608b175bb567ea3a315bf473ec3be459
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KRT6A TSHZ3 TSHZ2 OLFML2A PTPN3 ANOS1	4.76e-05	197	146	6	1e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 AMPH TSHZ2 ZIM2 KCNT2 VCAN	4.76e-05	197	146	6	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	RASGRF2 TSHZ2 NKD2 VCAN MACF1 DLG2	4.76e-05	197	146	6	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	TSHZ2 NKD2 PTPRS VCAN NID1 DLG2	4.90e-05	198	146	6	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2\|World / Primary Cells by Cluster	TSHZ3 SATB2 RTN4 DLG2 TNR CCDC144A	5.03e-05	199	146	6	f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCell	mild-B_memory\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	IKZF3 STRBP PELI1 BEND4 PRDM2 TNR	5.03e-05	199	146	6	e6ac9a0959b0de2c6a99298feb7715aa80ade1dd
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 CCDC146 CCDC150 SYT10 CFAP206 SEC14L5	5.03e-05	199	146	6	92778939e9d06599c7d06cfd8f4362b97ed0606b
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Layer_IV\|World / Primary Cells by Cluster	TSHZ3 SATB2 RTN4 DLG2 TNR CCDC144A	5.03e-05	199	146	6	e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TSHZ2 MUC16 CP NIBAN2 CLSTN1 PTPN3	5.18e-05	200	146	6	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DCHS2 CCDC146 MUC16 FTSJ1 CP PIK3C2G	5.18e-05	200	146	6	b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCell	NS-moderate-d_0-4-Epithelial\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PPP4R1 TSHZ2 STRBP MUC16 CP PTPN3	5.18e-05	200	146	6	64462a18afca3c1a8548a857924b8166058bf958
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	KRT6A TSHZ2 MUC16 CP SYNJ2 PTPRS	5.18e-05	200	146	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ2 NKD2 PTPRS VCAN PHACTR3 NID1	5.18e-05	200	146	6	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TSHZ2 NKD2 PTPRS VCAN PHACTR3 NID1	5.18e-05	200	146	6	cae972324d1dfea6efeaf6013f265c7c6bb48db4
Drug	dithranol	KRT6A KRT6B KRIT1 KRT6C	4.51e-06	18	145	4	CID000002202
Drug	SC-791	KRT6A KRT6B KRT6C	4.99e-06	6	145	3	CID010291510
Disease	cerebral palsy (implicated_via_orthology)	AGAP5 AGAP7P AGAP4 AGAP6	1.09e-07	10	143	4	DOID:1969 (implicated_via_orthology)
Disease	Colorectal Carcinoma	FLNC DNAH3 SATB2 RASGRF2 RTN4 CD109 SLC12A5 NF1 PTPRS ETAA1 NID1 PZP EPHA7	3.95e-05	702	143	13	C0009402
Disease	T-cell acute lymphoblastic leukemia (implicated_via_orthology)	RPL10L RPL10	6.97e-05	3	143	2	DOID:5603 (implicated_via_orthology)
Disease	Pachyonychia congenita syndrome	KRT6A KRT6B	1.39e-04	4	143	2	cv:C0265334
Disease	Pachyonychia Congenita, Jadassohn Lewandowsky Type	KRT6A KRT6B	1.39e-04	4	143	2	C1706595
Disease	pachyonychia congenita (is_implicated_in)	KRT6A KRT6B	1.39e-04	4	143	2	DOID:0050449 (is_implicated_in)
Disease	autistic disorder (implicated_via_orthology)	RPL10L RPL10	1.39e-04	4	143	2	DOID:12849 (implicated_via_orthology)
Disease	Pachyonychia Congenita, Type 2 (disorder)	KRT6A KRT6B	1.39e-04	4	143	2	C1721007
Disease	Pachyonychia Congenita	KRT6A KRT6B	2.31e-04	5	143	2	C0265334
Disease	nevus	NID1 PLA2G6	3.45e-04	6	143	2	EFO_0000625
Disease	Idiopathic generalized epilepsy	GABRD SLC12A5	3.45e-04	6	143	2	C0270850
Disease	spondyloepiphyseal dysplasia congenita (implicated_via_orthology)	RPL10L RPL10	3.45e-04	6	143	2	DOID:14789 (implicated_via_orthology)
Disease	pentachlorophenol measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022071
Disease	parathion measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022070
Disease	potassium chromate measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022072
Disease	mercuric chloride measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022068
Disease	heptachlor epoxide measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022067
Disease	methoxychlor measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022069
Disease	4,6-dinitro-o-cresol measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022053
Disease	2,4,5-trichlorophenol measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022052
Disease	azinphos methyl measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022055
Disease	aldrin measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022054
Disease	dicofol measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022060
Disease	disulfoton measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022062
Disease	dieldrin measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022061
Disease	endrin measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022064
Disease	endosulfan measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022063
Disease	heptachlor measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022066
Disease	ethion measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022065
Disease	chlorpyrifos measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022057
Disease	cadmium chloride measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022056
Disease	diazinon measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022059
Disease	dibutyl phthalate measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0022058
Disease	environmental exposure measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.44e-04	73	143	4	EFO_0008360
Disease	DDT metabolite measurement	TSHZ2 MUC16 PHACTR3 USH2A	4.68e-04	74	143	4	EFO_0007886
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	RPL10L RPL10	4.82e-04	7	143	2	DOID:0060807 (implicated_via_orthology)
Disease	Diabetes Mellitus	CP ALPK1 NR1I2	4.99e-04	32	143	3	C0011849
Disease	helping behavior measurement	BEND4 USH2A	6.41e-04	8	143	2	EFO_0008538
Disease	PARTINGTON X-LINKED MENTAL RETARDATION SYNDROME	BRWD3 RPL10	6.41e-04	8	143	2	C0796250
Disease	coronary aneurysm	DOCK2 TSHZ2 GRIN3A	6.51e-04	35	143	3	EFO_1000881
Disease	Abruptio Placentae	DOCK2 TDRD15	1.49e-03	12	143	2	EFO_1001754
Disease	blood cobalt measurement	TSHZ2 MUC16 PHACTR3 USH2A	1.50e-03	101	143	4	EFO_0007577
Disease	Intellectual Disability	TRIO BRWD3 AP4E1 ADRA2B NF1 MACF1 TAOK1 TAF2	1.56e-03	447	143	8	C3714756
Disease	hippocampal CA1 volume	SCFD2 STRBP VCAN	1.64e-03	48	143	3	EFO_0009394
Disease	Neurodegeneration with brain iron accumulation	CP PLA2G6	1.76e-03	13	143	2	cv:C2931845
Disease	Mental Retardation, X-Linked Nonsyndromic	FTSJ1 HUWE1	1.76e-03	13	143	2	C3501611
Disease	immature platelet count	PPP4R1 DOCK10 TAOK1 SEC14L5	1.79e-03	106	143	4	EFO_0803544
Disease	immature platelet fraction	PPP4R1 DOCK10 TAOK1 SEC14L5	2.34e-03	114	143	4	EFO_0009187
Disease	Autosomal Recessive Centronuclear Myopathy	SPEG ORAI1	2.35e-03	15	143	2	C3645536
Disease	immature platelet measurement	PPP4R1 DOCK10 TAOK1 SEC14L5	2.73e-03	119	143	4	EFO_0803541
Disease	blood nickel measurement	TSHZ2 MUC16 PHACTR3 USH2A	2.81e-03	120	143	4	EFO_0007583
Disease	calcium measurement	SCFD2 ICE2 CD109 CCNT1 KCNT2 SHOC1 MACF1 DMBT1 TOX2	3.62e-03	628	143	9	EFO_0004838
Disease	testosterone measurement	SCFD2 DCHS2 SATB2 TSHZ2 ICE2 C3orf38 NIBAN2 C2CD2 NF1 DGKK MACF1 USH2A TNS3 KNL1	3.68e-03	1275	143	14	EFO_0004908
Disease	eye colour measurement	PTPN3 PIK3C3 DMBT1 USH2A TNS3	4.28e-03	218	143	5	EFO_0009764
Disease	systemising measurement	TSHZ3 CLSTN1	4.61e-03	21	143	2	EFO_0010221
Disease	Profound Mental Retardation	AP4E1 ADRA2B NF1 TAF2	4.75e-03	139	143	4	C0020796
Disease	Mental Retardation, Psychosocial	AP4E1 ADRA2B NF1 TAF2	4.75e-03	139	143	4	C0025363
Disease	Mental deficiency	AP4E1 ADRA2B NF1 TAF2	4.75e-03	139	143	4	C0917816

Protein segments in the cluster

Peptide	Gene	Start	Entry
SEEDYAETIAHILSM	ALG11	441	Q2TAA5
FLDDSTAIQHYLTMT	AGAP4	126	Q96P64
ITSEGDHVTSVNEYM	CABS1	41	Q96KC9
DHVTSVNEYMLESDF	CABS1	46	Q96KC9
DVLASYTQATHDESM	VCAN	2641	P13611
SHGISYETMIEDVQS	CPA1	81	P15085
VHSQTSDNVDIEMQY	BEND4	221	Q6ZU67
HMEAVNLLSSNKYTE	AP2A1	76	O95782
HYSGQLTALTDENTM	ANKRD36BP1	81	Q96IX9
HSAEISDMAVNYENT	BRWD3	221	Q6RI45
AALSEMVEYITHNRN	PPP2R5C	71	Q13362
GAYHTLEEISQEMDN	CPA2	121	P48052
MDHQDPYSVQATAAI	ADRA2B	1	P18089
TSEVYLHEELQQDMQ	CCDC144CP	436	Q8IYA2
TTQTIDYQDTVNMLH	CCNT1	651	O60563
TVNPMETYEDQHSSE	CLSTN1	911	O94985
MEDNSALYESTSAHI	CCDC68	16	Q9H2F9
YHESSQMSSLVETFV	DHX29	956	Q7Z478
DVERQMTAQHYVTEF	ALPK1	1081	Q96QP1
FLDDSTAIQHYLTMT	AGAP6	126	Q5VW22
HMEAVNLLSSNRYTE	AP2A2	76	O94973
QEASMKLTESLHEVY	AMPH	71	P49418
FLEETTEYIHSNAME	AP4E1	906	Q9UPM8
ATMQHIDYQLETARS	CFAP206	221	Q8IYR0
HLYQTQAPSAEVEMT	PZP	1201	P20742
NHYMEQILNVSHEVT	PIK3C2G	1281	O75747
ADNLANEMTYITETE	PTPN3	396	P26045
MDNAVYTFETLLHQE	NIBAN2	441	Q96TA1
IHAGMETTYTVLQNE	CP	1046	P00450
EASSGMTHENYIILQ	ANOS1	476	P23352
TYQLVDIHVTEMESS	MUC16	14296	Q8WXI7
SQESLSDEEYAQMQH	DGKK	1066	Q5KSL6
LYDAELSQMQTHISD	KRT6C	301	P48668
EVSQDHETMAQVLFS	KATNBL1	146	Q9H079
LEAYHDVNVTGMQSS	GPAA1	196	O43292
LYDAELSQMQTHISD	KRT6A	301	P02538
ESVSNNVTEYMSTLH	MMRN1	536	Q13201
DEIQSHVRDSYSQMQ	ATP9B	496	O43861
QEQDMTDDLDHYTNT	GLYAT	61	Q6IB77
YDAELSQMQTHVSDT	KRT4	276	P19013
ESSNSTDYIAMHDVD	B4GALT7	151	Q9UBV7
YAVEASTMAQHAEVL	CARM1	211	Q86X55
IGQSYSEVMSLNEHS	ORAI1	56	Q96D31
QSMVDSIYADLSHSN	FSIP2	4861	Q5CZC0
HRIMSSSSYNQEDLI	FSIP2	6791	Q5CZC0
TINAHYTSRDELMEE	FAM135A	1111	Q9P2D6
LYDAELSQMQTHISD	KRT6B	301	P04259
IVFENTDLHSYVVMN	NID1	451	P14543
VDPNVDEHSVMTYLS	FLNC	241	Q14315
GHSSVEDAQATMELY	ISG20L2	321	Q9H9L3
NDMDITKSYTIEINH	KNL1	896	Q8NG31
QTENSLHMGYSALEI	KRIT1	201	O00522
QQAMDQLHYVTELTD	GBP2	136	P32456
EVASIDHISEANMEY	GABRD	71	O14764
VAYGLDSMDEVQSHI	ATP9A	411	O75110
DSMDEVQSHIFSIYT	ATP9A	416	O75110
STVGYDEMNDHQSTL	KCNT2	1066	Q6UVM3
HEEEYVLMQAISLFS	NR1I2	336	O75469
TVMDLLAHANYTFEV	EPHA7	401	Q15375
THEIPNIQTDSYESM	IKZF5	216	Q9H5V7
NTSTMEQATEYLLTH	HUWE1	1341	Q7Z6Z7
SLMHTIYEVVDASVN	NKD2	146	Q969F2
ETAREQLDTHMELYS	MACF1	6366	Q9UPN3
YDFTQMISETEILSN	ETAA1	216	Q9NY74
LNVTSDHMNTEITTY	ETAA1	776	Q9NY74
TQSVFEHYVQDAMEL	GRIN3A	381	Q8TCU5
MVQTEDQYSFIHEAL	PTPRS	1631	Q13332
ATMAVYVSVTDINDN	DCHS2	1276	Q6V1P9
STVTANVYVVDMNDH	PCDHAC2	561	Q9Y5I4
SQTAEYMQSHVEDFL	OTUD6B	181	Q8N6M0
SGTTDLYVDLQHMED	COG5	441	Q9UP83
TMENVVHELELYNTG	CD109	606	Q6YHK3
SVINNQYEETSIHMV	HYDIN	3591	Q4G0P3
TSEQTAEAMHYDISK	ICE2	251	Q659A1
LMQGYTASVDSTHQE	C2CD2	531	Q9Y426
QMASLELQQVTSDYH	CCDC150	526	Q8NCX0
ALMEQINSVSEHEYS	DNASE1L2	71	Q92874
QELHASDMPEYSVTN	DOCK10	1131	Q96BY6
MEHSQSDEYDILVFD	DOCK2	661	Q92608
TVVMEHYLEEFNNIS	DNAH3	2386	Q8TD57
ITINEANVLSVMSYD	GBA3	161	Q9H227
DSNYHLLMSVQESLE	GLUD1	461	P00367
HTIQGDYIDTMEELA	FMO5	426	P49326
EQNVMDYHGAEIVSL	C3orf38	186	Q5JPI3
TSVEVYEHINSMSLD	CYP4X1	176	Q8N118
TSEVYLHEELQQDMQ	CCDC144B	486	Q3MJ40
VSSATHYVAELNMDD	DHRSX	181	Q8N5I4
FLDDSTAIQHYLTMT	AGAP7P	126	Q5VUJ5
VAVYSEADRNSMHVD	MCCC1	76	Q96RQ3
SERQEIFTHIMDQYS	MAN2B2	201	Q9Y2E5
LMVNNYSLEEVTHEE	DLG2	246	Q15700
TSEVYLHEELQQDMQ	CCDC144A	486	A2RUR9
LNDYSLTKSHEMENV	IKZF3	26	Q9UKT9
VDTMYIANDTIHVAN	DMBT1	2226	Q9UGM3
SLYMTEEEQEHTDQL	SEC14L5	491	O43304
VLAMHEENVYTVESN	IFT140	486	Q96RY7
HLDNYKVMVSTEITD	PKD1L1	1256	Q8TDX9
DDVYIMDISSNISEN	PRDM2	551	Q13029
YVHKVASQMNTLEES	OLFML2A	141	Q68BL7
TVVVEYTHDSNTDMF	PELI1	86	Q96FA3
VEVVEMHESDISAYT	SLC12A5	911	Q9H2X9
NSHYEQLTVEVEQME	POTEA	476	Q6S8J7
FYTTQQAGDLEHMET	OR13D1	21	Q8NGV5
LNEYKSNEMEVHASS	PHACTR3	536	Q96KR7
EYTEHLAMLLSEEQS	MEI4	31	A8MW99
HMVSDEYEQLSSEAL	RPL10L	51	Q96L21
QMEELSTAVYSNDDL	RTN4	831	Q9NQC3
TEMIHEAAYRENTVG	PMPCA	206	Q10713
VEVSMEYDTASHTLN	SYT12	156	Q8IV01
EYDTASHTLNVAVMQ	SYT12	161	Q8IV01
SVIYNSTELFQDHML	USH2A	2191	O75445
TEKHSQDSYNSLSMD	SPDYA	256	Q5MJ70
LISDAVENMDSTLHY	PPP4R1	576	Q8TF05
VENMDSTLHYIHSDS	PPP4R1	581	Q8TF05
DGHVSNFVETEQMIY	SYNJ2	226	O15056
ELENLTAHMTLHYDT	TDRD15	266	B5MCY1
IHLVTEEEGSANMYA	PUS7L	576	Q9H0K6
EEEGSANMYAIHQVV	PUS7L	581	Q9H0K6
HMVSDEYEQLSSEAL	RPL10	51	P27635
QIVFTMVEAESEYVH	RASGRF2	246	O14827
QALYHSSIDALEVMS	YARS2	371	Q9Y2Z4
SNGDLVETVYTHDMR	TAF2	216	Q6P1X5
SDEEAVHYMQSLIDE	PIK3C3	851	Q8NEB9
DATVADMLQDVYHVV	SATB2	136	Q9UPW6
DSQIEVEEVSLYTHM	SHOC1	46	Q5VXU9
LAEQYDHSINEMLST	TAOK1	771	Q7L7X3
SYMTIQQKEDITHSA	STRBP	296	Q96SI9
YQRTVETMQSALDAE	MYH3	1591	P11055
SKDHIIETANMSYTN	MT-ND5	391	P03915
MIALTALHTEEENYN	SCFD2	311	Q8WU76
TLDAMTEIHEYNQDL	PLA2G6	661	O60733
ALVTMYSHEEDIDSA	SRP72	411	O76094
SEESYLHNLQEVTRM	TNS3	26	Q68CZ2
STVLHELTFQAMAYD	STXBP3	246	O00186
DVIMEALRSYNQEHS	RIC8A	16	Q9NPQ8
EQTNMDELSVTLDYL	SESTD1	36	Q86VW0
YTLLHDAVMSTQESE	CCDC146	71	Q8IYE0
DDSTASQHYLTMTII	AGAP5	151	A6NIR3
MEYSIKHSSEVDINT	XPO4	566	Q9C0E2
MAIDPDSLTYTVQHQ	SPEG	1311	Q15772
LDTMKAETNDSYHII	TFCP2	486	Q12800
DLYATVTQNVHEERM	SAGE1	526	Q9NXZ1
AMSTNDLYATITHDV	SAGE2P	331	A6NJ88
ETLAEYMGQTSDHES	TNR	96	Q92752
DYEMETQRISSSQQH	NF1	2576	P21359
ENVDQVSLSIAVMDY	SYT10	441	Q6XYQ8
SAAYDTLVELTVHMN	TSHZ2	221	Q9NRE2
AAYDTLVELTVHMNE	TSHZ3	221	Q63HK5
EESYAMETDSRHTVI	ZIM2	231	Q9NZV7
VTGLHDVDEYMQAQL	FTSJ1	121	Q9UET6
HVMRSNYETLVSLDD	ZNF786	36	Q8N393
TIQEMVHSEVAAYDS	TOX2	146	Q96NM4
EDYISNATHMLSRLE	TRIO	221	O75962
QQYSGMTHEDIVQES	ZC3H7B	646	Q9UGR2
NNTESILMSYDHVEL	WBP2	16	Q969T9
VQHVFTMEQEEYRSE	MYO7B	466	Q6PIF6