Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	IKZF3 ZNF337 ZNF460 ZNF875 MAX ZNF343 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF840P ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 NKX6-1 MYRF ZNF426 ZNF286A	2.48e-16	1412	104	36	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IKZF3 ZNF337 ZNF460 ZNF875 MAX ZNF343 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF840P ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 NKX6-1 ZNF763 ZNF426 ZNF286A	6.94e-16	1459	104	36	GO:0000977
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	IKZF3 ZNF460 MAX ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF840P ZNF774 ZBTB24 ZNF2 BCL6B ZNF14 ZNF18 SALL2 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF624 ZNF616 ZFP92 NKX6-1 ZNF763 ZNF426 ZNF286A	2.36e-11	1244	104	28	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	IKZF3 ZNF460 MAX ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF840P ZNF774 ZBTB24 ZNF2 BCL6B ZNF14 ZNF18 SALL2 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF624 ZNF616 ZFP92 NKX6-1 ZNF763 ZNF426 ZNF286A	3.91e-11	1271	104	28	GO:0000987
Domain	zf-C2H2	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	5.82e-28	693	104	38	PF00096
Domain	Znf_C2H2-like	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 RBM6 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	6.40e-27	796	104	39	IPR015880
Domain	Znf_C2H2/integrase_DNA-bd	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	9.51e-27	694	104	37	IPR013087
Domain	ZnF_C2H2	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 RBM6 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	1.12e-26	808	104	39	SM00355
Domain	ZINC_FINGER_C2H2_2	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	3.40e-26	775	104	38	PS50157
Domain	ZINC_FINGER_C2H2_1	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	3.73e-26	777	104	38	PS00028
Domain	-	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	6.66e-26	679	104	36	3.30.160.60
Domain	Znf_C2H2	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	1.34e-25	805	104	38	IPR007087
Domain	KRAB	ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZKSCAN2 ZNF101 ZNF112 ZNF235 ZNF774 ZNF587B ZNF2 ZNF599 ZNF14 ZNF18 ZNF550 ZNF347 ZNF500 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	5.22e-22	358	104	26	PS50805
Domain	KRAB	ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZKSCAN2 ZNF101 ZSCAN25 ZNF112 ZNF235 ZNF587B ZNF2 ZNF599 ZNF14 ZNF18 ZNF550 ZNF347 ZNF500 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	1.13e-21	369	104	26	SM00349
Domain	KRAB	ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZKSCAN2 ZNF101 ZSCAN25 ZNF112 ZNF235 ZNF587B ZNF2 ZNF599 ZNF14 ZNF18 ZNF550 ZNF347 ZNF500 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	1.21e-21	370	104	26	IPR001909
Domain	KRAB	ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZKSCAN2 ZNF101 ZNF112 ZNF235 ZNF587B ZNF2 ZNF599 ZNF14 ZNF18 ZNF550 ZNF347 ZNF500 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	9.43e-21	358	104	25	PF01352
Domain	zf-C2H2_6	ZNF234 MYNN ZBTB24 ZNF14 SALL2 ZNF500 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	2.20e-09	314	104	14	PF13912
Domain	SCAN	ZKSCAN2 ZSCAN25 ZNF18 ZSCAN5C ZNF500	1.48e-05	56	104	5	SM00431
Domain	SCAN_BOX	ZKSCAN2 ZSCAN25 ZNF18 ZSCAN5C ZNF500	1.76e-05	58	104	5	PS50804
Domain	SCAN	ZKSCAN2 ZSCAN25 ZNF18 ZSCAN5C ZNF500	1.76e-05	58	104	5	PF02023
Domain	SCAN_dom	ZKSCAN2 ZSCAN25 ZNF18 ZSCAN5C ZNF500	1.76e-05	58	104	5	IPR003309
Domain	Retrov_capsid_C	ZKSCAN2 ZSCAN25 ZNF18 ZSCAN5C ZNF500	1.92e-05	59	104	5	IPR008916
Domain	DUF4685	KIAA1614 C9orf50	3.07e-05	2	104	2	IPR032756
Domain	DUF4685	KIAA1614 C9orf50	3.07e-05	2	104	2	PF15737
Domain	Integrin_alpha	ITGA5 ITGAD	1.63e-03	11	104	2	PF00357
Domain	zf-H2C2_2	ZNF599 ZNF286A	2.68e-03	14	104	2	PF13465
Domain	Integrin_alpha_C_CS	ITGA5 ITGAD	3.50e-03	16	104	2	IPR018184
Domain	Integrin_alpha-2	ITGA5 ITGAD	4.43e-03	18	104	2	IPR013649
Domain	Integrin_alpha2	ITGA5 ITGAD	4.43e-03	18	104	2	PF08441
Domain	Integrin_alpha	ITGA5 ITGAD	4.43e-03	18	104	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGA5 ITGAD	4.43e-03	18	104	2	PS00242
Domain	Int_alpha_beta-p	ITGA5 ITGAD	4.94e-03	19	104	2	IPR013519
Domain	Int_alpha	ITGA5 ITGAD	4.94e-03	19	104	2	SM00191
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	MRE11 ZNF234 ATR ZNF337 ZNF460 ZNF875 MAX ZNF343 ZNF101 ZSCAN25 ZNF112 ITGA5 ZNF235 ZNF774 ZNF2 ZNF599 ZNF14 ZNF18 ZNF550 ZNF347 ZNF500 ZNF75A ZNF624 ZNF616 ZNF426 ZNF286A HTT	4.28e-10	1387	73	27	M734
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	MRE11 MAX ZNF101 ZSCAN25 ZNF112 ZNF235 ZNF2 ZNF14 ZNF18 ZNF347 ZNF814 ZNF624 ZNF616 ZNF426 ZNF286A	7.25e-06	768	73	15	MM14851
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	MRE11 MAX ZNF101 ZSCAN25 ZNF112 ZNF235 ZNF2 ZNF14 ZNF18 ZNF347 ZNF814 ZNF624 ZNF616 ZNF426 ZNF286A	1.96e-04	1022	73	15	MM15436
Pathway	REACTOME_REGULATION_OF_ENDOGENOUS_RETROELEMENTS	ZNF101 ZNF14 ZNF347 ZNF616	1.98e-04	56	73	4	MM17236
Pubmed	Rapid and efficient cloning of cDNAs encoding Krüppel-like zinc finger proteins by degenerate PCR.	MYNN ZNF101 ZNF347 ZNF814 ZNF624 ZNF616	1.03e-08	49	109	6	9630514
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	MAX MYNN ZNF235 ZBTB24 ZNF2 SART1 ZNF18 ZNF592 ZSCAN5C ZNF347 ZNF616 ZNF426 ZNF286A	1.57e-06	808	109	13	20412781
Pubmed	Mutant huntingtin downregulates myelin regulatory factor-mediated myelin gene expression and affects mature oligodendrocytes.	MYRF HTT	9.73e-06	2	109	2	25789755
Pubmed	The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.	MRE11 ATR	9.73e-06	2	109	2	21826105
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ZNF234 EPB41L4B PKD1L2 ITGA5 SART1 FAT1 ZNF592 ZNF616	1.90e-05	361	109	8	26167880
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF460 ZNF101 ZNF235 ZNF587B ZNF550 ZNF624	2.38e-05	181	109	6	37372979
Pubmed	Development of serous ovarian cancer is associated with the expression of homologous recombination pathway proteins.	MRE11 ATR	2.91e-05	3	109	2	24752797
Pubmed	Rapid activation of ATR by ionizing radiation requires ATM and Mre11.	MRE11 ATR	2.91e-05	3	109	2	16431910
Pubmed	Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters.	ZNF234 ZNF112 ZNF235	3.28e-05	20	109	3	12743021
Pubmed	Emergence of the ZNF91 Krüppel-associated box-containing zinc finger gene family in the last common ancestor of anthropoidea.	ZNF814 ZNF624 ZNF426	3.28e-05	20	109	3	7479878
Pubmed	Activation of the c-H-ras proto-oncogene by retrovirus insertion and chromosomal rearrangement in a Moloney leukemia virus-induced T-cell leukemia.	ZNF814 ZNF624 ZNF426	3.28e-05	20	109	3	2542606
Pubmed	Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937.	ZNF234 ZNF460 ZNF235	3.82e-05	21	109	3	7865130
Pubmed	Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.	ZNF347 ZNF814 ZNF624 ZNF616	3.89e-05	60	109	4	18023262
Pubmed	Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection.	MRE11 ATR	5.82e-05	4	109	2	19197236
Pubmed	Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complex.	MRE11 ATR	5.82e-05	4	109	2	20943970
Pubmed	NKX6.1 functions as a metastatic suppressor through epigenetic regulation of the epithelial-mesenchymal transition.	NKX6-1 CDH2	9.67e-05	5	109	2	26257059
Pubmed	Inactivation of the Nijmegen breakage syndrome gene leads to excess centrosome duplication via the ATR/BRCA1 pathway.	MRE11 ATR	9.67e-05	5	109	2	19244116
Pubmed	mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease.	CDH2 HTT	9.67e-05	5	109	2	32859226
Pubmed	The basic cleft of RPA70N binds multiple checkpoint proteins, including RAD9, to regulate ATR signaling.	MRE11 ATR	9.67e-05	5	109	2	18936170
Pubmed	Multiple cadherins are expressed in human fibroblasts.	FAT1 CDH2	9.67e-05	5	109	2	9199196
Pubmed	RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.	ATR SPSB1	2.02e-04	7	109	2	25916848
Pubmed	The Mre11-Rad50-Nbs1 complex acts both upstream and downstream of ataxia telangiectasia mutated and Rad3-related protein (ATR) to regulate the S-phase checkpoint following UV treatment.	MRE11 ATR	2.02e-04	7	109	2	17526493
Pubmed	RNF126-Mediated MRE11 Ubiquitination Activates the DNA Damage Response and Confers Resistance of Triple-Negative Breast Cancer to Radiotherapy.	MRE11 ATR	2.02e-04	7	109	2	36563124
Pubmed	Specific and ubiquitous expression of different Zn finger protein genes in the mouse.	ZNF814 ZNF624	2.02e-04	7	109	2	3143103
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	EPB41L4B ZNF875 SPSB1 WWP2 UVSSA FAM117B PLEKHM1 TBC1D4 RBM6 TVP23C ZFHX2 RASEF SEMA6A HTT	2.34e-04	1489	109	14	28611215
Pubmed	Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response.	MRE11 ATR	2.69e-04	8	109	2	15456891
Pubmed	RPA2 is a direct downstream target for ATR to regulate the S-phase checkpoint.	ATR PRIM1	2.69e-04	8	109	2	17035231
Pubmed	A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.	SALL2 ZNF814 ZNF624 NKX6-1	3.06e-04	102	109	4	19741146
Pubmed	A GO catalogue of human DNA-binding transcription factors.	ZNF234 ZNF235 ZNF592	3.14e-04	42	109	3	34673265
Pubmed	Single-cell analysis of murine long-term hematopoietic stem cells reveals distinct patterns of gene expression during fetal migration.	ITGA5 CDH2	3.45e-04	9	109	2	22276210
Pubmed	Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis.	ARHGEF19 CDH2	4.31e-04	10	109	2	30283008
Pubmed	A retrotransposon insertion in the 5' regulatory domain of Ptf1a results in ectopic gene expression and multiple congenital defects in Danforth's short tail mouse.	OTUD1 NKX6-1	4.31e-04	10	109	2	23437001
Pubmed	Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage.	MRE11 ATR	5.26e-04	11	109	2	15758953
Pubmed	Sonic hedgehog signaling directs patterned cell remodeling during cranial neural tube closure.	NKX6-1 CDH2	5.26e-04	11	109	2	33103996
Pubmed	Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.	MRE11 ATR	5.26e-04	11	109	2	15364958
Pubmed	A census of human transcription factors: function, expression and evolution.	IKZF3 MAX ZKSCAN2 ZBTB24 BCL6B ZNF14 SALL2 ZFHX2 NKX6-1 MYRF	5.82e-04	908	109	10	19274049
Pubmed	Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).	MRE11 ATR	6.29e-04	12	109	2	15149599
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ARHGEF19 ITGA5 PLEKHM1 FAT1 ZNF592 TTLL4 ZNF500 MYRF ZNF426 SOWAHB HTT	7.12e-04	1105	109	11	35748872
Pubmed	Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.	ITGA5 ITGAD	7.42e-04	13	109	2	20563599
Pubmed	Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer risk.	MRE11 ATR	7.42e-04	13	109	2	19064565
Pubmed	Organization of motor pools depends on the combined function of N-cadherin and type II cadherins.	NKX6-1 CDH2	7.42e-04	13	109	2	31235635
Pubmed	Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci.	ZNF814 ZNF624 ZNF426	9.44e-04	61	109	3	8662221
Pubmed	ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex.	MYNN ZBTB24 BCL6B	1.04e-03	63	109	3	34351428
Pubmed	Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells.	ZNF101 ZNF112	1.13e-03	16	109	2	8467795
Pubmed	Detailed comparative map of human chromosome 19q and related regions of the mouse genome.	ZNF235 ZNF347 ZNF616	1.24e-03	67	109	3	8812484
Pubmed	Leber Congenital Amaurosis – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	LCA5 GUCY2D	1.28e-03	17	109	2	20301475
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	CASP8AP2 STARD9 ZNF624 SEMA6A	1.40e-03	153	109	4	10718198
Pubmed	Meta-analysis identifies nine new loci associated with rheumatoid arthritis in the Japanese population.	ZNF774 PLD4	1.44e-03	18	109	2	22446963
Pubmed	TBX3 is dynamically expressed in pancreatic organogenesis and fine-tunes regeneration.	NKX6-1 CDH2	1.44e-03	18	109	2	36941669
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	MRE11 ATR MAX STAU1 SALL2 MRPL9	1.59e-03	396	109	6	26687479
Pubmed	Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.	NKX6-1 CDH2	1.78e-03	20	109	2	19439492
Pubmed	Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells.	NKX6-1 CDH2	1.78e-03	20	109	2	32855415
Pubmed	Nuclear Organization in the Spinal Cord Depends on Motor Neuron Lamination Orchestrated by Catenin and Afadin Function.	NKX6-1 CDH2	1.78e-03	20	109	2	29444423
Pubmed	A distinct response to endogenous DNA damage in the development of Nbs1-deficient cortical neurons.	MRE11 ATR	1.78e-03	20	109	2	22212482
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	MAX ZNF407 MYNN ZNF235 ZBTB24 ZNF2 ANKRD53 BCL6B ZNF592	1.79e-03	877	109	9	20211142
Pubmed	The DNA sequence and biology of human chromosome 19.	CBARP ZNF112 ZNF550 ZSCAN5C ZNF814	2.05e-03	284	109	5	15057824
Pubmed	Characterization and mapping of human genes encoding zinc finger proteins.	BCL6B ZNF763	2.16e-03	22	109	2	1946370
Pubmed	Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes.	BCL6B ZNF763	2.16e-03	22	109	2	1505991
Pubmed	β1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation.	ITGA5 CDH2	2.16e-03	22	109	2	38794925
Pubmed	Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo.	NKX6-1 CDH2	2.36e-03	23	109	2	18953410
Pubmed	Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8.	MRE11 CDH2	2.57e-03	24	109	2	19124014
Pubmed	Leber Congenital Amaurosis / Early-Onset Severe Retinal Dystrophy Overview	LCA5 GUCY2D	2.79e-03	25	109	2	30285347
Pubmed	Substrate specificities and identification of putative substrates of ATM kinase family members.	MRE11 ATR	2.79e-03	25	109	2	10608806
Pubmed	Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.	NKX6-1 CDH2	2.79e-03	25	109	2	18927156
Pubmed	Evaluating new candidate SNPs as low penetrance risk factors in sporadic breast cancer: a two-stage Spanish case-control study.	MRE11 ATR CLCA2	2.80e-03	89	109	3	18950845
Pubmed	The structural role of radial glial endfeet in confining spinal motor neuron somata is controlled by the Reelin and Notch pathways.	SEMA6A CDH2	3.01e-03	26	109	2	23988635
Pubmed	The tumor suppressor PTEN and the PDK1 kinase regulate formation of the columnar neural epithelium.	NKX6-1 CDH2	3.01e-03	26	109	2	26809587
Interaction	NOTCH2 interactions	ZNF460 OTUD1 ZNF407 ZKSCAN2 MYNN ZSCAN25 ZNF235 ZBTB24 ZNF587B CRKL ZNF592 ZNF624	2.10e-06	423	105	12	int:NOTCH2
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZNF234 ZNF460 ZNF875 ZNF112 ZNF235 ZNF587B ZNF599 ZNF550 ZSCAN5C ZNF347 ZNF814 ZNF616	2.76e-05	1192	109	12	chr19q13
Cytoband	20p11.1	ZNF337 FAM182A	3.63e-04	12	109	2	20p11.1
Cytoband	Ensembl 112 genes in cytogenetic band chr17p12	ZNF18 TVP23C ZNF286A	4.88e-04	64	109	3	chr17p12
Cytoband	19q13.43	ZNF550 ZSCAN5C ZNF814	1.19e-03	87	109	3	19q13.43
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	IKZF3 ZNF234 ZNF337 ZNF460 ZNF875 ZNF343 ZNF407 ZKSCAN2 MYNN ZNF101 ZSCAN25 ZNF112 ZNF235 ZXDA ZNF774 ZBTB24 ZNF491 ZNF587B ZNF2 ZNF599 BCL6B ZNF14 ZNF18 SALL2 ZNF550 ZNF592 ZSCAN5C ZNF347 ZNF500 ZFHX2 ZNF814 ZNF75A ZNF624 ZNF616 ZFP92 ZNF763 ZNF426 ZNF286A	4.46e-32	718	80	38	28
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-valve_cells\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGEF19 EPB41L4B ZSCAN25 ANKRD53 C9orf50 SOWAHB LRRC15	9.58e-08	153	108	7	1440f2716fea74e2c3eb2924eba3d63ebd08c997
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	GALNT15 FAM117B UBOX5 TVP23C ZNF624 ZNF616	6.02e-06	185	108	6	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	GALNT15 FAM117B UBOX5 TVP23C ZNF624 ZNF616	6.02e-06	185	108	6	02cbf492bc40abebaa93a3a208888afae72fbe06
Disease	apolipoprotein B measurement	ARHGEF19 AKNAD1 FAM117B ZNF101 ZNF112 ZNF235 ZNF14 MYRF HTT	3.41e-04	663	97	9	EFO_0004615
Disease	serum alanine aminotransferase measurement	GALNT15 ARHGEF19 EPB41L4B WWP2 ZNF101 STRADA RBM6 RASEF MYRF HTT	5.82e-04	869	97	10	EFO_0004735
Disease	Leber congenital amaurosis (implicated_via_orthology)	LCA5 GUCY2D	8.15e-04	13	97	2	DOID:14791 (implicated_via_orthology)
Disease	thalamus volume change measurement	SPSB1 FAT1	9.49e-04	14	97	2	EFO_0021496
Disease	eosinophil count	IKZF3 ATR TENT4A SPSB1 WWP2 MAX ZKSCAN2 MYNN ZNF491 IHO1 TBC1D4 FER1L5 MYRF	1.17e-03	1488	97	13	EFO_0004842
Disease	phosphatidylcholine 38:3 measurement	MYRF ALOX5AP	1.25e-03	16	97	2	EFO_0010385
Disease	Leber congenital amaurosis	LCA5 GUCY2D	1.25e-03	16	97	2	cv:C0339527
Disease	thyroxine measurement, triiodothyronine measurement	GALNT15 ZNF616	1.41e-03	17	97	2	EFO_0005130, EFO_0008392
Disease	Malignant neoplasm of endometrium	ATR MAX	1.58e-03	18	97	2	C0007103
Disease	Carcinoma in situ of endometrium	ATR MAX	1.58e-03	18	97	2	C0346191
Disease	Leber Congenital Amaurosis	LCA5 GUCY2D	2.37e-03	22	97	2	C0339527
Disease	Huntington's disease (is_implicated_in)	NPY2R HTT	2.59e-03	23	97	2	DOID:12858 (is_implicated_in)
Disease	lysophosphatidylcholine 18:0 measurement	GALNT15 MYRF	2.82e-03	24	97	2	EFO_0010359
Disease	breast cancer (implicated_via_orthology)	MRE11 ATR	3.05e-03	25	97	2	DOID:1612 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LIQHQRTHTGEKPFR	ZNF286A	481	Q9HBT8
FAHKVEHESRTQNGR	ALOX5AP	26	P20292
ASLDTRGSPKRHHFQ	CBARP	321	Q8N350
SAAKPGLHFIDQHRA	PYCARD	106	Q9ULZ3
FTTVRKANHRPHGAQ	C9orf50	231	Q5SZB4
DFQTFHASLQHRKPR	AMZ1	76	Q400G9
AEKTRPGSRHFHFIQ	C20orf204	56	A0A1B0GTL2
PGSRHFHFIQKNLTR	C20orf204	61	A0A1B0GTL2
SEFPHFRNNHKTART	CASP8AP2	141	Q9UKL3
KHQRGFQRSHGVQES	RASEF	456	Q8IZ41
SPGAANDHYHQRRQK	NPY2R	251	P49146
HTQPQRRASHGSEKK	ARHGEF19	121	Q8IW93
HPGHSLVSNTKQARA	ANKRD53	321	Q8N9V6
TFNPESVHGHRKAVA	FAT1	4286	Q14517
VNVHGTRGFTAPSKH	ANOS1	266	P23352
SEHRQALAAAKHRGP	OTUD1	196	Q5VV17
PRFQSAADKRAHHNA	MAX	16	P61244
TFLHPHGGTSRKVAQ	GUCY2D	511	Q02846
LPAFGSHERNRHVKD	IHO1	336	Q8IYA8
RFLHSGHVVHRDQKP	MAPK15	126	Q8TD08
NHSAVNRRHFSAPQK	FAM182A	16	Q5T1J6
PSHQRRKAASFQNLH	KIAA1614	1056	Q5VZ46
QHTSRKEIHFGSPQH	GALNT15	546	Q8N3T1
HAVASDPRHLRNKGS	FCRL5	936	Q96RD9
LNKHFRSHTGERPFI	MYNN	486	Q9NPC7
EGRSFNPNRHRLKHA	LCA5	661	Q86VQ0
LVRSSPHGKHGNRNS	CRKL	181	P46109
HQFHPGRRKRENKAS	TENT4A	161	Q5XG87
RGFSQPHSHAQALRQ	PKD1L2	1771	Q7Z442
HRRVSGAQKQPHQSA	ITGAD	826	Q13349
GNHSNIPFSRVNHSK	PLD4	416	Q96BZ4
GAVYSHRPNQHNTVK	PRIM1	81	P49642
GSLHHQQKREAPSRS	ITGA5	886	P08648
QSARVARKAGHHQTA	ATR	1926	Q13535
TFHQRTVGHTQRKSG	CEFIP	66	Q711Q0
HLARSHLAVTQPFGQ	FBH1	16	Q8NFZ0
PVNSRKHRAGVDIHS	HTT	2656	P42858
NRPANLKTHSRIHSG	BCL6B	366	Q8N143
THKPFEVEGNHRNTR	BCLAF3	631	A2AJT9
PSQHNAEFRGSTHRI	GAB4	276	Q2WGN9
RDKERQSPFHGNHAA	FAM117B	301	Q6P1L5
KEAGLNIFPTRHSHF	DNAI7	566	Q6TDU7
NHSKRGAFVQPHSLD	AKNAD1	701	Q5T1N1
FQARVQGSSALHPRH	MBOAT4	186	Q96T53
HKRSHTGERPFQCNQ	IKZF3	136	Q9UKT9
RGNLRAHFVGHKASP	SALL2	671	Q9Y467
AHFVGHKASPAARAQ	SALL2	676	Q9Y467
HHAFFRLRTPGNSKS	EPB41L4B	361	Q9H329
IVFPRQFSKHSGHLQ	CDH2	141	P19022
HGVSRSKTIPAHFFQ	LGSN	96	Q5TDP6
PSQGHKSFRVVHRRQ	PLEKHM1	511	Q9Y4G2
KSHAQERHSGNFPGR	RBM6	36	P78332
QSQVVFSHRGFKARP	UBOX5	126	O94941
ISHGQRQRVVHDFPK	STRADA	221	Q7RTN6
SRHITFAGKFEPVQH	UVSSA	551	Q2YD98
AHRALSSKPQHFQVR	FER1L5	156	A0AVI2
GKNSLTHISPRVFQH	LRRC15	181	Q8TF66
RKHTRPTFSGQQIFA	NKX6-1	236	P78426
SSHLRFQKAPVGQHL	STARD9	3816	Q9P2P6
IHQNRSKHGSTNFIP	MRE11	216	P49959
PSQHQHRRELFKGFV	SOWAHB	41	A6NEL2
ANGRYSLKVHVNHSP	CLCA2	681	Q9UQC9
AEHNFVAKAHGSPRV	CLEC17A	296	Q6ZS10
RHSGAAKTRTQVHQP	PGBD2	436	Q6P3X8
RHFFKNLGVVVAPHT	MRPL9	191	Q9BYD2
HVIQPSQALASGFHR	USP17L3	141	A6NCW0
ANLFKHQAVHGARRP	ZFP92	361	A6NM28
HQAVHGARRPAKAET	ZFP92	366	A6NM28
VHQRIHTGEKPFRCN	ZNF624	461	Q9P2J8
SSFIRHQRTHSGEKP	ZNF343	366	Q6P1L6
SRHRQPVKNSGHSGL	WWP2	216	O00308
FIRHNRTHSGQKPLE	ZNF599	466	Q96NL3
NFVRHNRIHTGEKPF	ZNF599	521	Q96NL3
RHQRTHNGDKPFVCS	ZNF460	241	Q14592
HLTRHQRVHSGEKPF	ZNF460	266	Q14592
SSLNRHQKAHAGDPR	ZNF2	326	Q9BSG1
GHPSRKFHQVDINSF	TVP23C	191	Q96ET8
HSVGFLHRDIKPSNF	TTBK1	146	Q5TCY1
FVRHQRSHTGQKPYI	ZNF616	256	Q08AN1
RAHTLSQHAVQPKYR	ZFHX2	996	Q9C0A1
SQGHHTKDFTRAAPN	STAU1	431	O95793
HRHPVAQSTDAIRGK	SPSB1	76	Q96BD6
FVGHKPGRNTTQRHR	SEMA6A	41	Q9H2E6
SNFITHQRTHTGVKP	ZNF774	276	Q6NX45
SFHTPNSLRKHIRNN	ZNF592	1021	Q92610
ANLAVHRRAHTGEKP	ZSCAN25	471	Q6NSZ9
RHQQIHTGRKPFICS	ZNF840P	566	A6NDX5
TPKEAFRQLSHRFHG	SART1	721	O43290
VHEGSQKSQPRRRHA	TBC1D4	326	O60343
PSQFQAHRRIHTGEK	ZNF234	356	Q14588
GKVFTQNSHLVRHRG	ZNF347	351	Q96SE7
IHQRSHTGERPFKCN	ZBTB24	311	O43167
SFSNHQRVHSGKRPY	ZNF587B	256	E7ETH6
KGFSRSSHLQGHQRV	ZNF112	616	Q9UJU3
TFIRHNRTHTGEKPF	ZNF550	301	Q7Z398
TQAKLGAHQRSHFEP	ZXDA	371	P98168
PNLFQIHQRTHTGKR	ZNF101	181	Q8IZC7
SFNRNIRTDTGHQPH	ZNF491	51	Q8N8L2
SNFGAHQRIHTGEKP	ZKSCAN2	816	Q63HK3
NFNRHQRVHTGEKPY	ZNF18	506	P17022
PNLFRHKRAHSGAFV	ZNF875	566	P10072
VSHGNEVRHSSKPQF	ZNF407	691	Q9C0G0
NLHTHQRTHTGEKPF	ZNF75A	231	Q96N20
HPSFRTQERNHTGEK	ZNF763	156	Q0D2J5
QVHISHQEARGPSFK	SPAG11A	71	Q6PDA7
RSIREHQKLNHFPGS	TTLL4	651	Q14679
SFQSHQRVHTGEKPF	ZNF235	501	Q14590
AFGRPATLRRHQKTH	ZSCAN5C	476	A6NGD5
NSFQIHGRTHTGEKP	ZNF426	321	Q9BUY5
FSNHQRVHTGKRPYE	ZNF814	311	B7Z6K7
SFSNHQRVHTGKRPY	ZNF814	366	B7Z6K7
SNFSTHQRVHTGEKP	ZNF500	366	O60304
HQRTHSGEKPFACRQ	ZNF337	366	Q9Y3M9
YQPFQRHERTHAGQK	ZNF14	181	P17017
GVSHHKPINRRVSSQ	MYO3A	1461	Q8NEV4
HAGSQFSRAGSVPHK	MYRF	726	Q9Y2G1