Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDC42BPG RFK MAK HK2 ATR PDGFRB MATK RPS6KA2 NTRK3 GLYCTK CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EEF2K EIF2AK4 EIF2AK1 ALK	3.99e-09	709	164	24	GO:0016773
GeneOntologyMolecularFunction	kinase activity	CDC42BPG RFK MAK HK2 ATR PDGFRB MATK RPS6KA2 NTRK3 GLYCTK CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EEF2K EIF2AK4 EIF2AK1 ALK	1.68e-08	764	164	24	GO:0016301
GeneOntologyMolecularFunction	protein kinase activity	CDC42BPG MAK ATR PDGFRB MATK RPS6KA2 NTRK3 CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EEF2K EIF2AK4 EIF2AK1 ALK	2.32e-08	600	164	21	GO:0004672
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDC42BPG MAK ATR RPS6KA2 CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EEF2K EIF2AK4 EIF2AK1	1.67e-07	446	164	17	GO:0004674
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDC42BPG RFK MAK HK2 ATR PDGFRB MATK RPS6KA2 NTRK3 POLR2A GLYCTK CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EEF2K EIF2AK4 EIF2AK1 ALK	1.97e-07	938	164	25	GO:0016772
GeneOntologyMolecularFunction	protein serine kinase activity	CDC42BPG MAK ATR RPS6KA2 CILK1 NEK1 NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1	9.90e-06	363	164	13	GO:0106310
GeneOntologyMolecularFunction	magnesium ion binding	ENOSF1 CDC42BPG RPS6KA2 POLR2A CILK1 NT5C3B BPNT1 PRKACA ENO3	2.10e-04	247	164	9	GO:0000287
GeneOntologyMolecularFunction	beta-adrenergic receptor kinase activity	GRK2 GRK3	3.98e-04	4	164	2	GO:0047696
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH6 DNAH11	4.05e-04	18	164	3	GO:0008569
Domain	Protein_kinase_ATP_BS	CDC42BPG MAK PDGFRB MATK RPS6KA2 NTRK3 CILK1 NEK1 GRK2 GRK3 NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1 ALK	8.12e-09	379	166	18	IPR017441
Domain	Kinase-like_dom	CDC42BPG MAK ATR PDGFRB MATK RPS6KA2 NTRK3 CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EEF2K EIF2AK4 EIF2AK1 ALK	1.55e-08	542	166	21	IPR011009
Domain	Prot_kinase_dom	CDC42BPG MAK PDGFRB MATK RPS6KA2 NTRK3 CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1 ALK	7.58e-08	489	166	19	IPR000719
Domain	PROTEIN_KINASE_DOM	CDC42BPG MAK PDGFRB MATK RPS6KA2 NTRK3 CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1 ALK	8.61e-08	493	166	19	PS50011
Domain	PROTEIN_KINASE_ATP	CDC42BPG MAK PDGFRB MATK RPS6KA2 NTRK3 CILK1 NEK1 GRK2 GRK3 NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1 ALK	1.49e-07	459	166	18	PS00107
Domain	AGC-kinase_C	CDC42BPG RPS6KA2 GRK2 GRK3 PRKACA PRKACG PRKCE	6.21e-07	56	166	7	IPR000961
Domain	AGC_KINASE_CTER	CDC42BPG RPS6KA2 GRK2 GRK3 PRKACA PRKACG PRKCE	6.21e-07	56	166	7	PS51285
Domain	S_TK_X	CDC42BPG RPS6KA2 GRK2 GRK3 PRKACA PRKACG PRKCE	6.21e-07	56	166	7	SM00133
Domain	Pkinase	CDC42BPG MAK RPS6KA2 CILK1 NEK1 GRK2 GRK3 STRADA NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1	1.63e-06	381	166	15	PF00069
Domain	Ser/Thr_kinase_AS	CDC42BPG MAK RPS6KA2 CILK1 NEK1 GRK2 GRK3 NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1	3.86e-06	357	166	14	IPR008271
Domain	S_TKc	CDC42BPG MAK RPS6KA2 CILK1 NEK1 GRK2 GRK3 NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1	4.11e-06	359	166	14	SM00220
Domain	PROTEIN_KINASE_ST	CDC42BPG MAK RPS6KA2 CILK1 NEK1 GRK2 GRK3 NRK TBK1 PRKACA PRKACG PRKCE EIF2AK4 EIF2AK1	4.53e-06	362	166	14	PS00108
Domain	Plexin_repeat	SEMA7A PLXDC1 PLXND1 PLXNB2 SEMA4A	8.66e-06	32	166	5	IPR002165
Domain	PSI	SEMA7A PLXDC1 PLXND1 PLXNB2 SEMA4A	8.66e-06	32	166	5	PF01437
Domain	-	WSB1 SEMA7A TBL1Y COPB2 PLXND1 PLXNB2 WDR19 WDR93 WDR87 NUP133 PAN2 SEMA4A	4.43e-05	333	166	12	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WSB1 SEMA7A TBL1Y COPB2 PLXND1 PLXNB2 WDR19 WDR93 WDR87 NUP133 PAN2 SEMA4A	4.70e-05	335	166	12	IPR015943
Domain	PSI	SEMA7A PLXDC1 PLXND1 PLXNB2 SEMA4A	5.33e-05	46	166	5	SM00423
Domain	Factor_5/8	F5 F8	7.85e-05	2	166	2	IPR024715
Domain	Semap_dom	SEMA7A PLXND1 PLXNB2 SEMA4A	1.57e-04	31	166	4	IPR001627
Domain	SEMA	SEMA7A PLXND1 PLXNB2 SEMA4A	1.57e-04	31	166	4	PS51004
Domain	Sema	SEMA7A PLXND1 PLXNB2 SEMA4A	1.57e-04	31	166	4	SM00630
Domain	Sema	SEMA7A PLXND1 PLXNB2 SEMA4A	1.57e-04	31	166	4	PF01403
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	IPR013602
Domain	DHC_N2	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	IPR011704
Domain	MT	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	PF12777
Domain	AAA_8	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	PF12780
Domain	CNH	CDC42BPG GARNL3 NRK	2.34e-04	14	166	3	SM00036
Domain	AAA_5	DNAH3 DNAH6 DNAH11	2.34e-04	14	166	3	PF07728
Domain	Na/sul_symport_CS	SLC13A1 SLC13A5	2.34e-04	3	166	2	IPR031312
Domain	NA_SULFATE	SLC13A1 SLC13A5	2.34e-04	3	166	2	PS01271
Domain	DHC_fam	DNAH3 DNAH6 DNAH11	2.90e-04	15	166	3	IPR026983
Domain	Dynein_heavy	DNAH3 DNAH6 DNAH11	2.90e-04	15	166	3	PF03028
Domain	CNH	CDC42BPG GARNL3 NRK	2.90e-04	15	166	3	PF00780
Domain	Dynein_heavy_dom	DNAH3 DNAH6 DNAH11	2.90e-04	15	166	3	IPR004273
Domain	CNH	CDC42BPG GARNL3 NRK	2.90e-04	15	166	3	PS50219
Domain	CNH_dom	CDC42BPG GARNL3 NRK	2.90e-04	15	166	3	IPR001180
Domain	-	ENOSF1 ENO3	4.66e-04	4	166	2	3.30.390.10
Domain	-	ENOSF1 ENO3	4.66e-04	4	166	2	3.20.20.120
Domain	Enolase_C-like	ENOSF1 ENO3	4.66e-04	4	166	2	IPR029065
Domain	Enolase_N-like	ENOSF1 ENO3	4.66e-04	4	166	2	IPR029017
Domain	Pkinase_C	CDC42BPG RPS6KA2 PRKACA PRKCE	5.18e-04	42	166	4	PF00433
Domain	PLAC	ADAMTS19 ADAMTS3 ADAMTS6	6.02e-04	19	166	3	PS50900
Domain	PLAC	ADAMTS19 ADAMTS3 ADAMTS6	6.02e-04	19	166	3	IPR010909
Domain	PSI	SEMA7A PLXND1 PLXNB2 SEMA4A	6.19e-04	44	166	4	IPR016201
Domain	Na/sul_symport	SLC13A1 SLC13A5	7.72e-04	5	166	2	IPR001898
Domain	Cu-oxidase_3	F5 F8	7.72e-04	5	166	2	IPR011707
Domain	MULTICOPPER_OXIDASE1	F5 F8	7.72e-04	5	166	2	PS00079
Domain	Cu_oxidase_CS	F5 F8	7.72e-04	5	166	2	IPR033138
Domain	Na_sulph_symp	SLC13A1 SLC13A5	7.72e-04	5	166	2	PF00939
Domain	Cu-oxidase_3	F5 F8	7.72e-04	5	166	2	PF07732
Domain	ADAM_spacer1	ADAMTS19 ADAMTS3 ADAMTS6	1.07e-03	23	166	3	IPR010294
Domain	ADAM_spacer1	ADAMTS19 ADAMTS3 ADAMTS6	1.07e-03	23	166	3	PF05986
Domain	Cu_oxidase_Cu_BS	F5 F8	1.15e-03	6	166	2	IPR002355
Domain	Peptidase_M12B_ADAM-TS	ADAMTS19 ADAMTS3 ADAMTS6	1.22e-03	24	166	3	IPR013273
Domain	zf-C2H2	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZFHX4 ZNF30 PRDM15 ZNF554	1.34e-03	693	166	15	PF00096
Domain	ZINC_FINGER_C2H2_2	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZFHX4 TRMT1L ZNF30 PRDM15 ZNF554	1.52e-03	775	166	16	PS50157
Domain	ZINC_FINGER_C2H2_1	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZFHX4 TRMT1L ZNF30 PRDM15 ZNF554	1.56e-03	777	166	16	PS00028
Domain	GPCR_kinase	GRK2 GRK3	1.60e-03	7	166	2	IPR000239
Domain	Znf_C2H2-like	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZFHX4 TRMT1L ZNF30 PRDM15 ZNF554	1.99e-03	796	166	16	IPR015880
Domain	Sel1	SEL1L3 EEF2K	2.12e-03	8	166	2	PF08238
Domain	Znf_C2H2	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZFHX4 TRMT1L ZNF30 PRDM15 ZNF554	2.23e-03	805	166	16	IPR007087
Domain	ZnF_C2H2	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZFHX4 TRMT1L ZNF30 PRDM15 ZNF554	2.31e-03	808	166	16	SM00355
Domain	Plexin_cytopl	PLXND1 PLXNB2	2.71e-03	9	166	2	PF08337
Domain	Sel1-like	SEL1L3 EEF2K	2.71e-03	9	166	2	IPR006597
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXND1 PLXNB2	2.71e-03	9	166	2	IPR013548
Domain	Plexin	PLXND1 PLXNB2	2.71e-03	9	166	2	IPR031148
Domain	IG_FLMN	FLNB AREL1	3.37e-03	10	166	2	SM00557
Domain	Glyco_transf_8	UGGT2 LARGE1	3.37e-03	10	166	2	PF01501
Domain	Glyco_trans_8	UGGT2 LARGE1	3.37e-03	10	166	2	IPR002495
Domain	Filamin	FLNB AREL1	4.10e-03	11	166	2	PF00630
Domain	aa-tRNA-synt_IIb	SARS2 EIF2AK4	4.10e-03	11	166	2	IPR002314
Domain	FILAMIN_REPEAT	FLNB AREL1	4.10e-03	11	166	2	PS50194
Domain	Filamin/ABP280_rpt	FLNB AREL1	4.10e-03	11	166	2	IPR001298
Domain	Filamin/ABP280_repeat-like	FLNB AREL1	4.10e-03	11	166	2	IPR017868
Domain	tRNA-synt_2b	SARS2 EIF2AK4	4.10e-03	11	166	2	PF00587
Domain	Tyr_kinase_rcpt_2_CS	NTRK3 ALK	4.10e-03	11	166	2	IPR002011
Domain	Pkinase_C	CDC42BPG RPS6KA2 PRKCE	4.29e-03	37	166	3	IPR017892
Domain	RECEPTOR_TYR_KIN_II	NTRK3 ALK	4.89e-03	12	166	2	PS00239
Domain	Pep_M12B_propep	ADAMTS19 ADAMTS3 ADAMTS6	4.98e-03	39	166	3	PF01562
Domain	Peptidase_M12B_N	ADAMTS19 ADAMTS3 ADAMTS6	4.98e-03	39	166	3	IPR002870
Domain	TYR_PHOSPHATASE_PTP	PTPN23 PTPN5 PTP4A3	4.98e-03	39	166	3	PS50055
Domain	DISINTEGRIN_1	ADAMTS19 ADAMTS3 ADAMTS6	5.35e-03	40	166	3	PS00427
Domain	Reprolysin	ADAMTS19 ADAMTS3 ADAMTS6	5.35e-03	40	166	3	PF01421
Domain	ADAM_MEPRO	ADAMTS19 ADAMTS3 ADAMTS6	5.35e-03	40	166	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS19 ADAMTS3 ADAMTS6	5.35e-03	40	166	3	PS50214
Domain	Peptidase_M12B	ADAMTS19 ADAMTS3 ADAMTS6	5.35e-03	40	166	3	IPR001590
Domain	PTPase_domain	PTPN23 PTPN5 PTP4A3	5.74e-03	41	166	3	IPR000242
Domain	Disintegrin_dom	ADAMTS19 ADAMTS3 ADAMTS6	5.74e-03	41	166	3	IPR001762
Domain	Y_phosphatase	PTPN23 PTPN5 PTP4A3	5.74e-03	41	166	3	PF00102
Domain	-	DPM1 EIF2B5 UGGT2 LARGE1	5.89e-03	81	166	4	3.90.550.10
Domain	-	F5 F8	6.66e-03	14	166	2	2.60.40.420
Domain	PLAC	ADAMTS19 ADAMTS6	6.66e-03	14	166	2	PF08686
Domain	-	ZBTB20 ZNF234 ZNF674 SALL4 ZNF699 ZNF25 ZKSCAN5 ZXDA ZXDB ZFHX4 ZNF30 PRDM15 ZNF554	7.72e-03	679	166	13	3.30.160.60
Domain	Tyr_kinase_cat_dom	PDGFRB MATK NTRK3 ALK	7.87e-03	88	166	4	IPR020635
Domain	TyrKc	PDGFRB MATK NTRK3 ALK	7.87e-03	88	166	4	SM00219
Domain	Nucleotide-diphossugar_trans	DPM1 EIF2B5 UGGT2 LARGE1	7.87e-03	88	166	4	IPR029044
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	CUL3 ZBTB20 PDGFRB MATK RPS6KA2 NTRK3 CILK1 AREL1 TBK1 PRKCE EIF2AK1 ALK	3.17e-07	372	169	12	22939624
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ENOSF1 CDC42BPG FLNB VPS37A ZBTB20 TSHZ2 NSD2 INPP5A PLCXD1 RPS6KA2 SH3BP2 CILK1 ANKRD44 GRK3 SHANK2 TMEM184A TBK1 SEL1L3 ENPP5 PRKCE AKAP13 EIF2AK4 PRDM15	9.96e-07	1489	169	23	28611215
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	CDC42BPG EPS8L2 HK2 LARS2 PLXNB2 TUBGCP6 MTR EIF2AK4	3.42e-06	183	169	8	31932471
Pubmed	Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.	AVPR1A NTRK3 GRIA1 CHRNA2 SLC6A2 S100B GRK3 NRXN2 NOS2	1.75e-05	300	169	9	19086053
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CUL3 CDC42BPG HK2 ATR DPM1 ZXDB TBK1 EIF2B5 MTR ANKRD28 UGGT2 AKAP13 EIF2AK4	1.93e-05	650	169	13	38777146
Pubmed	Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.	GRIA1 SLC6A2 S100B GRK3 NOS2	1.93e-05	67	169	5	20398908
Pubmed	Sublethal simulated ischemia promotes delayed resistance against ischemia via ATP-sensitive (K+) channels in murine myocytes: role of PKC and iNOS.	PRKCE NOS2	2.35e-05	2	169	2	15025939
Pubmed	Desmopressin acetate as a haemostatic elevator in individuals with combined deficiency of factors V and VIII: a clinical trial.	F5 F8	2.35e-05	2	169	2	26599105
Pubmed	Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.	ATR MTA1	2.35e-05	2	169	2	20427275
Pubmed	The molecular basis of factor V and VIII procofactor activation.	F5 F8	2.35e-05	2	169	2	19765210
Pubmed	Factor VIII/V C-domain swaps reveal discrete C-domain roles in factor VIII function and intracellular trafficking.	F5 F8	2.35e-05	2	169	2	28057741
Pubmed	The factor VIII D1241E polymorphism is associated with decreased factor VIII activity and not with activated protein C resistance levels.	F5 F8	2.35e-05	2	169	2	15735794
Pubmed	Cardiac hyporesponsiveness in severe sepsis is associated with nitric oxide-dependent activation of G protein receptor kinase.	GRK2 NOS2	2.35e-05	2	169	2	28526706
Pubmed	Increased factor VIII coagulant activity levels in male carriers of the factor V R2 polymorphism.	F5 F8	2.35e-05	2	169	2	17287628
Pubmed	Semaphorin4A-Plexin D1 Axis Induces Th2 and Th17 While Represses Th1 Skewing in an Autocrine Manner.	PLXND1 SEMA4A	2.35e-05	2	169	2	32971928
Pubmed	Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3.	GRK2 GRK3	2.35e-05	2	169	2	10198406
Pubmed	Activated protein C has a regulatory role in factor VIII function.	F5 F8	2.35e-05	2	169	2	33512448
Pubmed	G-protein coupled receptor kinase 2 and 3 expression in human detrusor cultured smooth muscle cells.	GRK2 GRK3	2.35e-05	2	169	2	11762794
Pubmed	Factor XIII Val34Leu and the risk of venous thromboembolism in factor V Leiden carriers.	F5 F8	2.35e-05	2	169	2	11091190
Pubmed	The deubiquitinase Otud7b suppresses cone photoreceptor degeneration in mouse models of retinal degenerative diseases.	MAK OTUD7B	2.35e-05	2	169	2	38510130
Pubmed	Cloning of GRK2 cDNA from S49 murine lymphoma cells.	GRK2 GRK3	2.35e-05	2	169	2	8638670
Pubmed	Dissecting the roles of GRK2 and GRK3 in μ-opioid receptor internalization and β-arrestin2 recruitment using CRISPR/Cas9-edited HEK293 cells.	GRK2 GRK3	2.35e-05	2	169	2	33060647
Pubmed	Duplicated zinc finger protein genes on the proximal short arm of the human X chromosome: isolation, characterization and X-inactivation studies.	ZXDA ZXDB	2.35e-05	2	169	2	8268913
Pubmed	Characterization of the cAMP-dependent protein kinase catalytic subunit Cgamma expressed and purified from sf9 cells.	PRKACA PRKACG	2.35e-05	2	169	2	15039079
Pubmed	G protein--coupled receptor kinases.	GRK2 GRK3	2.35e-05	2	169	2	8035170
Pubmed	PCIF1, a novel human WW domain-containing protein, interacts with the phosphorylated RNA polymerase II.	POLR2A PCIF1	2.35e-05	2	169	2	12565871
Pubmed	Conservative mutations in the C2 domains of factor VIII and factor V alter phospholipid binding and cofactor activity.	F5 F8	2.35e-05	2	169	2	22613792
Pubmed	Phosphorylation of the platelet-derived growth factor receptor-beta by G protein-coupled receptor kinase-2 reduces receptor signaling and interaction with the Na(+)/H(+) exchanger regulatory factor.	PDGFRB GRK2	2.35e-05	2	169	2	15271984
Pubmed	Wild-type LRP6 inhibits, whereas atherosclerosis-linked LRP6R611C increases PDGF-dependent vascular smooth muscle cell proliferation.	PDGFRB LRP6	2.35e-05	2	169	2	21245321
Pubmed	Novel blockade of protein kinase A-mediated phosphorylation of AMPA receptors.	GRIA1 PRKACA	2.35e-05	2	169	2	16436600
Pubmed	Th1 cells promote neurite outgrowth from cortical neurons via a mechanism dependent on semaphorins.	SEMA7A SEMA4A	2.35e-05	2	169	2	20946887
Pubmed	Plexin-B2 and Plexin-D1 in dendritic cells: expression and IL-12/IL-23p40 production.	PLXND1 PLXNB2	2.35e-05	2	169	2	22916243
Pubmed	The coatomer protein beta'-COP, a selective binding protein (RACK) for protein kinase Cepsilon.	COPB2 PRKCE	2.35e-05	2	169	2	9360998
Pubmed	Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.	GRK2 PRKACA	2.35e-05	2	169	2	11278469
Pubmed	Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.	SEMA7A PLXND1 PLXNB2	3.11e-05	13	169	3	10520995
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH6 DNAH11	3.94e-05	14	169	3	9373155
Pubmed	Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development.	PLXNB2 S100B SEMA4A	4.91e-05	15	169	3	21122816
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNB ATR DDX60 RNF112 SALL4 AKAP13 EIF2AK4	6.26e-05	202	169	7	33005030
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	CUL3 ZBTB20 HK2 RPS6KA2 POLR2A PLXND1 PLXNB2 NEK1 ADAMTS6 PRKACA KCNS2 PRKCE DNAH11	6.34e-05	730	169	13	34857952
Pubmed	Human NK cells express CC chemokine receptors 4 and 8 and respond to thymus and activation-regulated chemokine, macrophage-derived chemokine, and I-309.	GRK2 GRK3	7.02e-05	3	169	2	10754297
Pubmed	Distinct expression patterns of ICK/MAK/MOK protein kinases in the intestine implicate functional diversity.	MAK CILK1	7.02e-05	3	169	2	24244486
Pubmed	An unusual fusion gene EML4-ALK in a patient with congenital mesoblastic nephroma.	NTRK3 ALK	7.02e-05	3	169	2	34378283
Pubmed	Molecular cloning of a tissue-specific protein kinase (C gamma) from human testis--representing a third isoform for the catalytic subunit of cAMP-dependent protein kinase.	PRKACA PRKACG	7.02e-05	3	169	2	2342480
Pubmed	Brain ischemia and reperfusion activates the eukaryotic initiation factor 2alpha kinase, PERK.	EIF2AK4 EIF2AK1	7.02e-05	3	169	2	11389192
Pubmed	Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor.	PLXND1 SEMA4A	7.02e-05	3	169	2	26648031
Pubmed	Factor V Leiden improves in vivo hemostasis in murine hemophilia models.	F5 F8	7.02e-05	3	169	2	16359510
Pubmed	Coagulation procofactor activation by factor XIa.	F5 F8	7.02e-05	3	169	2	20456758
Pubmed	Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cepsilon- and A-dependent mechanisms in rats and mice.	PRKACA PRKCE	7.02e-05	3	169	2	16793902
Pubmed	Factor V Leiden mutation and high FVIII are associated with an increased risk of VTE in women with breast cancer during adjuvant tamoxifen - results from a prospective, single center, case control study.	F5 F8	7.02e-05	3	169	2	25592075
Pubmed	Cell signaling through the protein kinases cAMP-dependent protein kinase, protein kinase Cepsilon, and RAF-1 regulates amphotropic murine leukemia virus envelope protein-induced syncytium formation.	PRKACA PRKCE	7.02e-05	3	169	2	15741175
Pubmed	Phosphorylation of the platelet-derived growth factor receptor-beta and epidermal growth factor receptor by G protein-coupled receptor kinase-2. Mechanisms for selectivity of desensitization.	PDGFRB GRK2	7.02e-05	3	169	2	12381737
Pubmed	The switch-like expression of heme-regulated kinase 1 mediates neuronal proteostasis following proteasome inhibition.	EIF2AK4 EIF2AK1	7.02e-05	3	169	2	32329716
Pubmed	The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits.	PRKACA PRKACG	7.02e-05	3	169	2	19383776
Pubmed	S100B dysregulation during brain development affects synaptic SHANK protein networks via alteration of zinc homeostasis.	S100B SHANK2	7.02e-05	3	169	2	34741005
Pubmed	CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner.	MAK CILK1	7.02e-05	3	169	2	23743448
Pubmed	Interpretation of correlations between coagulation factors FV, FVIII and vWF in normal and type 2 diabetes mellitus patients.	F5 F8	7.02e-05	3	169	2	22032085
Pubmed	Differential effects of CC chemokines on CC chemokine receptor 5 (CCR5) phosphorylation and identification of phosphorylation sites on the CCR5 carboxyl terminus.	GRK2 GRK3	7.02e-05	3	169	2	10085131
Pubmed	Co-segregation of thrombophilic disorders in factor V Leiden carriers; the contributions of factor VIII, factor XI, thrombin activatable fibrinolysis inhibitor and lipoprotein(a) to the absolute risk of venous thromboembolism.	F5 F8	7.02e-05	3	169	2	12368162
Pubmed	Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor.	GRK2 GRK3	7.02e-05	3	169	2	7761854
Pubmed	The N-termini of GRK2 and GRK3 simulate the stimulating effects of RKIP on β-adrenoceptors.	GRK2 GRK3	7.02e-05	3	169	2	31604529
Pubmed	Active cAMP-dependent protein kinase incorporated within highly purified HIV-1 particles is required for viral infectivity and interacts with viral capsid protein.	PRKACA PRKACG	7.02e-05	3	169	2	12842892
Pubmed	Thrombomodulin-dependent effect of factor VLeiden mutation on factor XIII activation.	F5 F8	7.02e-05	3	169	2	21774968
Pubmed	Orphanin FQ/nociceptin-mediated desensitization of opioid receptor-like 1 receptor and mu opioid receptors involves protein kinase C: a molecular mechanism for heterologous cross-talk.	GRK2 GRK3	7.02e-05	3	169	2	12130708
Pubmed	Regulation of ATR activity via the RNA polymerase II associated factors CDC73 and PNUTS-PP1.	ATR POLR2A	7.02e-05	3	169	2	30541148
Pubmed	Human phosphorylated CTD-interacting protein, PCIF1, negatively modulates gene expression by RNA polymerase II.	POLR2A PCIF1	7.02e-05	3	169	2	18294453
Pubmed	ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.	MTA1 ZFHX4	7.02e-05	3	169	2	24440720
Pubmed	Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization.	GRK2 PRKACA	7.02e-05	3	169	2	12639913
Pubmed	Characterization of multiple phosphorylation sites on the AMPA receptor GluR1 subunit.	GRIA1 PRKACA	7.02e-05	3	169	2	8663994
Pubmed	A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer.	HK2 ALK	7.02e-05	3	169	2	27132509
Pubmed	Renal Interstitial Platelet-Derived Growth Factor Receptor-β Cells Support Proximal Tubular Regeneration.	PDGFRB POLR2A	7.02e-05	3	169	2	29444905
Pubmed	The Role of the Second Extracellular Loop of Norepinephrine Transporter, Neurotrophin-3 and Tropomyosin Receptor Kinase C in T Cells: A Peripheral Biomarker in the Etiology of Schizophrenia.	NTRK3 SLC6A2	7.02e-05	3	169	2	34445205
Pubmed	PKC and PKA regulate AChR dynamics at the neuromuscular junction of living mice.	CHRNA2 PRKACA	7.02e-05	3	169	2	24260568
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	CUL3 IQSEC3 NTRK3 GRIA1 GRK3 SHANK2 PRKACA PRKCE	7.47e-05	281	169	8	28706196
Pubmed	Identification of different proteins binding to Na, K-ATPase α1 in LPS-induced ARDS cell model by proteomic analysis.	FLNB NOP56 POLR2A COPB2 DPM1 DHX15	7.72e-05	144	169	6	35681168
Pubmed	Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.	NTRK3 GRIA1 NRXN2 ADGRL3	1.21e-04	52	169	4	24613359
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA7A PLXND1 PLXNB2 SEMA4A	1.21e-04	52	169	4	26633812
Pubmed	Identification of the proteome complement of humanTLK1 reveals it binds and phosphorylates NEK1 regulating its activity.	ATR NEK1	1.40e-04	4	169	2	28426283
Pubmed	Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration.	ZBTB20 PRKACA	1.40e-04	4	169	2	23507145
Pubmed	EF-hand domains of MCFD2 mediate interactions with both LMAN1 and coagulation factor V or VIII.	F5 F8	1.40e-04	4	169	2	20007547
Pubmed	KLHL4, a novel p53 target gene, inhibits cell proliferation by activating p21WAF/CDKN1A.	CUL3 KLHL4	1.40e-04	4	169	2	32753315
Pubmed	PDGFR blockade is a rational and effective therapy for NPM-ALK-driven lymphomas.	PDGFRB ALK	1.40e-04	4	169	2	23064464
Pubmed	Phosphorylation of serine 2843 in ryanodine receptor-calcium release channel of skeletal muscle by cAMP-, cGMP- and CaM-dependent protein kinase.	RYR1 PRKACA	1.40e-04	4	169	2	8380342
Pubmed	Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulin.	F5 F8	1.40e-04	4	169	2	9525969
Pubmed	Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function.	GRK2 GRK3	1.40e-04	4	169	2	8917529
Pubmed	ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.	ADAMTS19 ADAMTS3	1.40e-04	4	169	2	28088271
Pubmed	Rap1GAP2 is a new GTPase-activating protein of Rap1 expressed in human platelets.	PRKACA PRKACG	1.40e-04	4	169	2	15632203
Pubmed	Structural characterization of carbohydrate binding by LMAN1 protein provides new insight into the endoplasmic reticulum export of factors V (FV) and VIII (FVIII).	F5 F8	1.40e-04	4	169	2	23709226
Pubmed	Hierarchical organization of multi-site phosphorylation at the CXCR4 C terminus.	GRK2 GRK3	1.40e-04	4	169	2	23734232
Pubmed	NPM-ALK up-regulates iNOS expression through a STAT3/microRNA-26a-dependent mechanism.	NOS2 ALK	1.40e-04	4	169	2	23338972
Pubmed	iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated dystrophin.	RYR1 NOS2	1.40e-04	4	169	2	32693782
Pubmed	Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP.	GRIA1 PRKACA	1.40e-04	4	169	2	17972919
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH3 DNAH6	1.40e-04	4	169	2	11175280
Pubmed	Class 4 Semaphorins and Plexin-B receptors regulate GABAergic and glutamatergic synapse development in the mammalian hippocampus.	PLXNB2 SEMA4A	1.40e-04	4	169	2	29981480
Pubmed	Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complex.	F5 F8	1.40e-04	4	169	2	12717434
Pubmed	14-3-3 proteins and survival kinases cooperate to inactivate BAD by BH3 domain phosphorylation.	RPS6KA2 PRKACA	1.40e-04	4	169	2	10949026
Pubmed	Reduced expression of G protein-coupled receptor kinases in schizophrenia but not in schizoaffective disorder.	GRK2 GRK3	1.40e-04	4	169	2	21784156
Pubmed	Prothrombotic polymorphisms in patients with Raynaud's phenomenon and migraine.	F5 F8	1.40e-04	4	169	2	23238545
Pubmed	TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation.	TBK1 NOS2	1.40e-04	4	169	2	24562310
Pubmed	Acidosis Mediates the Switching of Gs-PKA and Gi-PKCε Dependence in Prolonged Hyperalgesia Induced by Inflammation.	PRKACA PRKCE	1.40e-04	4	169	2	25933021
Pubmed	Protein kinase A-induced phosphorylation of the p65 subunit of nuclear factor-kappaB promotes Schwann cell differentiation into a myelinating phenotype.	PRKACA PRKACG	1.40e-04	4	169	2	18385332
Interaction	EGLN1 interactions	CUL3 NTRK3 POLR2A BPNT1 TBK1 PYGL NAA40 ALK	8.13e-07	91	165	8	int:EGLN1
GeneFamily	Dyneins, axonemal	DNAH3 DNAH6 DNAH11	1.77e-04	17	119	3	536
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS19 ADAMTS3 ADAMTS6	2.49e-04	19	119	3	50
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZBTB20 ZNF234 TSHZ2 ZNF674 SALL4 ZNF699 ZNF25 ZNF414 ZKSCAN5 ZXDA ZXDB ZNF30 PRDM15 ZNF554	2.67e-04	718	119	14	28
GeneFamily	Protein phosphatase 6 regulatory subunits	ANKRD44 ANKRD28	6.33e-04	6	119	2	699
GeneFamily	Plexins	PLXND1 PLXNB2	1.50e-03	9	119	2	683
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	PDGFRB NTRK3 ALK	2.30e-03	40	119	3	321
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	CDC42BPG SH3BP2 PLEKHD1 GRK2 GRK3 AKAP13	2.43e-03	206	119	6	682
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	TSHZ2 ZFHX4	4.26e-03	15	119	2	529
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000	ZBTB20 ADAMTS3 TMEM45A PDGFRB AVPR1A INPP5A NTRK3 PLXND1 GCNT1 TMBIM6 PICALM SLC3A1 BPNT1 PTP4A3 GRK3 ADAMTS6 NRK SEL1L3 ENPP5 PYGL EEF2K ENO3	2.60e-06	905	167	22	gudmap_kidney_P0_JuxtaGlom_Ren1_1000
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	MAK HK2 GCNT1 NCAPH RYR1 AREL1 PTP4A3 MROH1 IFRD2	4.32e-08	186	170	9	74eb69a52090f9e2426a47e03a1c478ee0cfec18
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDX60 RPS6KA2 F5 TUBGCP6 ANKRD44 GRK3 DNAH6 ENO3	3.82e-07	175	170	8	c1c722db42da9b8a2a46e516ddb83d9be5e2e504
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	WSB1 ADAMTS19 ZBTB20 TSHZ2 ANKRD44 NRK UGGT2 ADGRL3	7.13e-07	190	170	8	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	356C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	FLNB EPS8L2 LAMP5 PTP4A3 SEL1L3 TSPAN13 ZNF554	3.15e-06	163	170	7	ae9c5eb19657ea94b7f2357cbc8679acd697b8fe
ToppCell	356C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FLNB EPS8L2 LAMP5 PTP4A3 SEL1L3 TSPAN13 ZNF554	3.28e-06	164	170	7	fed26f4ac36a2b0722bc7b9f91659c5e0cf4d53a
ToppCell	(3)_DC_plasmacytoid\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	FLNB SEMA7A LAMP5 PLEKHD1 DHX15 SEL1L3 TSPAN13	3.85e-06	168	170	7	8a913db9b2a1a4ff96fb139734a3834e6aa263f1
ToppCell	(3)_MNP-(3)_DC_plasmacytoid\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	FLNB SEMA7A LAMP5 PLEKHD1 PTP4A3 SEL1L3 TSPAN13	3.85e-06	168	170	7	13c160ea1a19b47d2e7e2dae818c8dcde4e3e377
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RFK EPS8L2 COX6A1 TMBIM6 SLC3A1 SEMA4A ENO3	4.33e-06	171	170	7	b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCell	droplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RFK EPS8L2 COX6A1 TMBIM6 SLC3A1 SEMA4A ENO3	4.33e-06	171	170	7	e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HK2 SH3BP2 F5 GRK3 CD300LB PYGL ENO3	4.50e-06	172	170	7	e72966ced5f2ee9e24ce9fd820d99a69a482a607
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HK2 SH3BP2 F5 GRK3 CD300LB PYGL ENO3	4.50e-06	172	170	7	83730ea3b240b8e2f2a9fb6c34dd1408050867ff
ToppCell	CF-Lymphoid-pDC\|CF / Disease state, Lineage and Cell class	FLNB LAMP5 SEL1L3 TSPAN13 MTR EEF2K EIF2AK4	5.23e-06	176	170	7	dd1e529a9e413bcaab43584afbe059e1464ffb53
ToppCell	CV-Severe-4\|Severe / Virus stimulation, Condition and Cluster	IQSEC3 EPS8L2 HK2 SEMA7A TMEM45A INPP5A F5	6.06e-06	180	170	7	cf84a01e6a33e5d27ad7be1d9069a0370b5116d1
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|390C / Donor, Lineage, Cell class and subclass (all cells)	MAK GCNT1 NCAPH RYR1 AREL1 MROH1 TRMT1L	6.75e-06	183	170	7	228092290dbb08785c4eda224e3ad03e99e10fab
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ADAMTS3 TSHZ2 NEK1 ZFHX4 NRK KCNS2 HSD11B1	7.00e-06	184	170	7	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-pDC\|bone_marrow / Manually curated celltypes from each tissue	FLNB SEMA7A RPS6KA2 LAMP5 PLEKHD1 SEL1L3 TSPAN13	7.00e-06	184	170	7	2817d530863e85dfdcd143b7a3dc5fc58a9cd98b
ToppCell	Mild-Lymphoid-pDC-\|Mild / Condition, Lineage, Cell class and cell subclass	FLNB SEMA7A LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	7.51e-06	186	170	7	1d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCell	Mild-Lymphoid-pDC\|Mild / Condition, Lineage, Cell class and cell subclass	FLNB SEMA7A LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	7.51e-06	186	170	7	7fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 PDGFRB NTRK3 PTP4A3 ADGRL3 DNAH11 LARGE1	7.78e-06	187	170	7	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	MAK HK2 GCNT1 NCAPH RYR1 AREL1 IFRD2	7.78e-06	187	170	7	1eed2c1a05e80a7c8f639437c117afe0c18dfb0c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 PDGFRB NTRK3 PTP4A3 ADGRL3 DNAH11 LARGE1	7.78e-06	187	170	7	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	WSB1 ZBTB20 TSHZ2 ANKRD44 NRK UGGT2 ADGRL3	8.93e-06	191	170	7	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	F5 ZNF414 SLC13A5 KCNS2 SOAT2 ADGRL3	9.87e-06	128	170	6	e100629f6038e32176ffcc81bd06bd175df46cef
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CILK1 PLXND1 PICALM F8 ZXDB TSPAN31 PRDM15	1.09e-05	197	170	7	789c97ca9d1e28df3353140046047f11fbccc1d0
ToppCell	Biopsy_Other_PF-Immune-pDCs\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SEMA7A LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13 EIF2AK4	1.09e-05	197	170	7	598a130eb7afb1bb95da64a964218362627feb49
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPS8L2 ADAMTS3 TMEM45A AVPR1A CNMD S100B TSPAN13	1.09e-05	197	170	7	6e111ba16fc8adde782b3f7da250248cddf11228
ToppCell	(5)_Dendritic_cell-(54)_pDC\|(5)_Dendritic_cell / shred on Cell_type and subtype	FLNB IQSEC3 EPS8L2 SEMA7A LAMP5 SEL1L3 TSPAN13	1.13e-05	198	170	7	fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCell	severe-pDC\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FLNB SEMA7A RPS6KA2 LAMP5 SLC9C2 SEL1L3 TSPAN13	1.13e-05	198	170	7	22da4a29b9ff8b94d98bc69b4632a2a58d5dd9e6
ToppCell	severe-pDC\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FLNB SEMA7A RPS6KA2 LAMP5 SEL1L3 TSPAN13 EIF2AK4	1.13e-05	198	170	7	3c4820a8391088682fb3e47b914f872533bae227
ToppCell	Sepsis-Bac-SEP-Myeloid-pDC\|Bac-SEP / Disease, condition lineage and cell class	FLNB SEMA7A LAMP5 PLEKHD1 ZDHHC4 SEL1L3 TSPAN13	1.17e-05	199	170	7	7f6569de050262f3d8d9d41c0f0cc139de85c0cb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-DC-DC3-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAK LAMP5 CD300LB SEL1L3 TSPAN13 EIF2AK4 DNAH6	1.17e-05	199	170	7	7271dbeca9aa838b88ad44d00059263a29c0316b
ToppCell	mild-unassigned\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PDGFRB TUBGCP6 S100B AREL1 NEK1 NUP133 ENPP5	1.20e-05	200	170	7	ca0a08bf162c954f037a56aa0cbb8b5d7c6ffec0
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_ALM_Macc1_Lrg1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ADAMTS3 RPS6KA2 LAMP5 RYR1 ZFHX4 SLC13A5	1.78e-05	142	170	6	d08e1880425d285c4433014fe0242ac7ff7734af
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 DDX60 F5 CD300LB PYGL ENO3	2.43e-05	150	170	6	34774b015adecc2be56a471fda8994e89a6ad93e
ToppCell	368C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BTBD8 AVPR1A ZNF674 EIF2B5 NAA40 PRDM15	2.82e-05	154	170	6	f29316d4b4dcdb23bd427d78068e65a9802f7f07
ToppCell	368C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	BTBD8 AVPR1A ZNF674 EIF2B5 NAA40 PRDM15	2.82e-05	154	170	6	66065c0763c83d98084ca6969694c3af37e43274
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS19 PLXDC1 PDGFRB NTRK3 LRP6 ALK	3.14e-05	157	170	6	bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCell	Control-Endothelial-Epi-like-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8L2 SALL4 TUBGCP6 MROH1 HSD11B1 DNAH6	3.14e-05	157	170	6	2c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCell	Control-Endothelial-Epi-like\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	EPS8L2 SALL4 TUBGCP6 MROH1 HSD11B1 DNAH6	3.14e-05	157	170	6	4d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCell	URO-Other-RBC\|URO / Disease, Lineage and Cell Type	EPS8L2 VPS37A LAMP5 PTP4A3 SEL1L3 TSPAN13	3.49e-05	160	170	6	558f3b0719e2461a69e1b93b08e21675e8d07a5a
ToppCell	URO-Other\|URO / Disease, Lineage and Cell Type	EPS8L2 VPS37A LAMP5 PTP4A3 SEL1L3 TSPAN13	3.49e-05	160	170	6	b0923e6bacfaba8ca40aa5706bf270eea0938b0a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PDGFRB ASPG PLXND1 ADAMTS6 PYGL EEF2K	4.01e-05	164	170	6	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 PDGFRB NTRK3 COX6A1 NCAPH ADGRL3	4.15e-05	165	170	6	cd8de98af8a1a8a6c81d71fae807cc07f319f4c9
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 PDGFRB NTRK3 COX6A1 NCAPH ADGRL3	4.15e-05	165	170	6	4f83ac71efc57be3668d8db1e62bad05dc6a5e2b
ToppCell	normal-na-Lymphocytic_B-B_atypical-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	IQSEC3 SEMA7A GCNT1 SLC3A1 SEL1L3 LARGE1	4.29e-05	166	170	6	30a180b67572c3f4fb3a291f271f855e1b20005e
ToppCell	367C-Myeloid-Dendritic-pDC\|367C / Donor, Lineage, Cell class and subclass (all cells)	SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13 EIF2AK4	4.43e-05	167	170	6	650de8cd5df070639b8aa292aacead739cfdb02c
ToppCell	Healthy_Control-Lymphoid-pDC\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FLNB EPS8L2 SEMA7A PLXDC1 LAMP5 TSPAN13	4.74e-05	169	170	6	a4e9b8b2f0338203455ba941b8f99bf4884d26f0
ToppCell	COVID-19-Heart-Adipocyte\|Heart / Disease (COVID-19 only), tissue and cell type	TBL1Y GRK3 ZFHX4 ANKRD28 ENPP5 PYGL	4.74e-05	169	170	6	bd39f85b48207955f80ca120a11e15a0124117b9
ToppCell	Healthy_Control-Lymphoid-pDC-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	FLNB EPS8L2 SEMA7A PLXDC1 LAMP5 TSPAN13	4.74e-05	169	170	6	338ce99897cb522b86edd603f75bc15ec4dfcda3
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic-pDC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13 EIF2AK4	5.75e-05	175	170	6	37c2d4e0b6e9a3171931797ce9a54f3347288e57
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 PDGFRB NTRK3 PTP4A3 ADGRL3 DNAH11	6.13e-05	177	170	6	4943d040eee0f9dceaddc7498171281d170e271f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 PDGFRB NTRK3 PTP4A3 ADGRL3 DNAH11	6.13e-05	177	170	6	3f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell	COPD-Myeloid-pDC\|COPD / Disease state, Lineage and Cell class	SEMA7A RPS6KA2 LAMP5 PLEKHD1 SEL1L3 TSPAN13	6.13e-05	177	170	6	415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 AVPR1A SLC6A2 ADAMTS6 HSD11B1 SOAT2	6.52e-05	179	170	6	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	moderate-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FLNB SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13	6.72e-05	180	170	6	1d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANKRD29 RFK EPS8L2 PLXND1 GCNT1 F8	6.72e-05	180	170	6	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	Severe-Lymphoid-pDC-\|Severe / Condition, Lineage, Cell class and cell subclass	SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13 EIF2AK4	6.93e-05	181	170	6	277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCell	Severe-Lymphoid-pDC\|Severe / Condition, Lineage, Cell class and cell subclass	SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13 EIF2AK4	6.93e-05	181	170	6	2caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCell	normal_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	SEMA7A OTUD7B USP44 S100B TSPAN13 SMPD2	7.15e-05	182	170	6	8dd79fef8f8463ad3194f9cc07c6cacf2c886304
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ADAMTS19 PLXDC1 PDGFRB RPS6KA2 GRK3 LRP6	7.59e-05	184	170	6	689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCell	BAL-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	7.82e-05	185	170	6	c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCell	Bac-SEP-Myeloid-pDC\|Bac-SEP / Disease, Lineage and Cell Type	FLNB SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13	7.82e-05	185	170	6	3de50b2042f22b0fb62ff12c76d85cc67649a0bd
ToppCell	BAL-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	7.82e-05	185	170	6	f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCell	BAL-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	7.82e-05	185	170	6	3cb816fc9541c04b4436e21d984216cfbbacff98
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 SEL1L3 DNAH6 ADGRL3 DNAH11 LARGE1	8.06e-05	186	170	6	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	BAL-Mild-Myeloid-pDC-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	FLNB LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	8.06e-05	186	170	6	b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCell	mild-unassigned\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	PDGFRB TUBGCP6 S100B AREL1 NUP133 ENPP5	8.06e-05	186	170	6	5b2e1a58916f392fa1156bf9210df528775248ff
ToppCell	BAL-Mild-Myeloid-pDC-pDC-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLNB LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	8.06e-05	186	170	6	79aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCell	BAL-Mild-Myeloid-pDC\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	FLNB LAMP5 PLEKHD1 SLC9C2 SEL1L3 TSPAN13	8.06e-05	186	170	6	d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCell	myeloid-pDC\|myeloid / Lineage and Cell class	FLNB EPS8L2 SEMA7A LAMP5 SEL1L3 TSPAN13	8.54e-05	188	170	6	a2dc4bbeca2bdc00c51825dd65a699c54c72f241
ToppCell	COVID-19_Mild-pDC\|COVID-19_Mild / Disease condition and Cell class	FLNB EPS8L2 SEMA7A LAMP5 SEL1L3 TSPAN13	8.54e-05	188	170	6	62d33d2990d4a2d32bd0863147e47f656df1966e
ToppCell	COVID-19_Mild-pDC-\|COVID-19_Mild / Disease condition and Cell class	FLNB EPS8L2 SEMA7A LAMP5 SEL1L3 TSPAN13	8.54e-05	188	170	6	a75c2cf2f8dae343c13aaa66b637658b935ed10a
ToppCell	(0)_Myeloid-(01)_Dendritic_cell\|(0)_Myeloid / immune cells in Peripheral Blood (logTPM normalization)	FLNB EPS8L2 LAMP5 SLC6A2 SEL1L3 TSPAN13	9.06e-05	190	170	6	e9507bb0c8ff3d071402731a9b8cfe1bba93fab0
ToppCell	facs-Lung-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAK RFX4 WDR93 SHANK2 NKPD1 DNAH6	9.06e-05	190	170	6	fe844559b95832845d2e8d3ab4b57e3d558bc372
ToppCell	facs-Lung-nan-3m-Epithelial-Ciliated_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAK RFX4 WDR93 SHANK2 NKPD1 DNAH6	9.06e-05	190	170	6	e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ANKRD29 EPS8L2 ASPG OTUD7B SHANK2 TSPAN13	9.06e-05	190	170	6	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	COVID-19-Heart-Mito_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TSHZ2 KLHL41 F8 RYR1 PTP4A3 ENO3	9.06e-05	190	170	6	ea74e0e38bcaba125b48c88331e9ba09228d3178
ToppCell	(3)_MNP-(3)_DC_activated\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	SEMA7A SLC6A2 NRXN2 TSPAN13 ENO3 DNAH11	9.32e-05	191	170	6	0353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ZBTB20 CNMD GCNT1 S100B ZFHX4 ADGRL3	9.59e-05	192	170	6	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	(3)_Chondrocytes\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	EPS8L2 CNMD S100B NRK TSPAN13 SLC13A5	9.59e-05	192	170	6	5d2b4830d025d3dbdf5623ce1c28d1036e1984a8
ToppCell	11.5-Airway-Mesenchymal-Cartilage\|Airway / Age, Tissue, Lineage and Cell class	SEMA7A CNMD GCNT1 S100B NRK PYGL	9.87e-05	193	170	6	d4779d92a4dd4b8b656383e6f4fce76d3bd70931
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SEMA7A LAMP5 PLEKHD1 SEL1L3 TSPAN13 AKAP13	9.87e-05	193	170	6	30abf991ac17c18679ab7d633e7549c0ce841920
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS19 NTRK3 GRIA1 NRXN2 NRK KLHL4	9.87e-05	193	170	6	adc9fc94f9ec686a417d08c0b8b7b7ab687afec0
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	FLNB TSHZ2 F5 SHANK2 LRP6 SLC13A5	9.87e-05	193	170	6	503a979328c68b096680b71359a26f02fafdff35
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKRD29 IQSEC3 TSHZ2 RPS6KA2 F8 KLHL4	9.87e-05	193	170	6	bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATK RNF112 GRIA1 LAMP5 NRXN2 PRKCE	9.87e-05	193	170	6	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	10x5'v1-week_17-19-Myeloid_DC-DC-pDC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EPS8L2 LAMP5 SLC9C2 SEL1L3 TSPAN13 EIF2AK4	9.87e-05	193	170	6	2a48e72f3df2ad64e1680fca759be8fd2190771e
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATK RNF112 GRIA1 LAMP5 NRXN2 PRKCE	9.87e-05	193	170	6	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT1 ZNF25 GRK2 SEL1L3 TSPAN13 ENPP5	9.87e-05	193	170	6	4aee372ba2c0351b0221d0d468707d1ad21526d6
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HK2 LAMP5 PLXNB2 CD300LB PYGL SEMA4A	9.87e-05	193	170	6	52f5b0fbb8ca706206c65e7edbb1ddbd380aebae
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MATK RNF112 GRIA1 LAMP5 NRXN2 PRKCE	9.87e-05	193	170	6	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Large_Intestine-Distal-3m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GCNT1 ZNF25 GRK2 SEL1L3 TSPAN13 ENPP5	9.87e-05	193	170	6	aaa5042388dc451bff384c6bb237348f08280a08
ToppCell	PCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANKRD29 EPS8L2 CNMD SHANK2 SEL1L3 TSPAN13	9.87e-05	193	170	6	4b8202fcfe639a73f69a13f48fc3601ade256346
ToppCell	Control-Lymphoid-pDC\|Lymphoid / Condition, Lineage and Cell class	FLNB LAMP5 PLXNB2 CD300LB TSPAN13 EIF2AK4	1.02e-04	194	170	6	5f95a5a35f73222dbe2ca52cc580f4774f641403
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 PDGFRB TSHZ2 NTRK3 ZFHX4 ADGRL3	1.02e-04	194	170	6	c49f72441b3557e2c3a9c4239e68c0cf0652814b
ToppCell	Fibroblasts-Pericytes\|Fibroblasts / lung cells shred on cell class, cell subclass, sample id	PDGFRB NTRK3 DHX15 SLC6A2 PTP4A3 ADGRL3	1.04e-04	195	170	6	c2ebc0b33bda9b35b9ef26d69e5d2c6acfdb6ff1
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB LAMP5 PLEKHD1 PTP4A3 SEL1L3 TSPAN13	1.04e-04	195	170	6	06051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB LAMP5 PLEKHD1 PTP4A3 SEL1L3 TSPAN13	1.04e-04	195	170	6	3aa44633c72658545aa2b35bf9d532c62f36a451
ToppCell	(3)_Chondrocytes-(34)_Chondro-progen\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	EPS8L2 ZBTB20 TMEM45A GRIA1 S100B TSPAN13	1.04e-04	195	170	6	d00cb2fab25f2026a9668a7f0686938a2e7155e2
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SFTPC^high_distal_(9)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANKRD29 EPS8L2 CNMD SHANK2 SEL1L3 TSPAN13	1.10e-04	197	170	6	22b26bac3a99b20c73bfa6e6f81026d064eaa9e8
Drug	8-azido cyclic AMP	GRK2 GRK3 PRKACA PRKACG PYGL	1.63e-07	18	168	5	CID000115296
Drug	lavendustin A	MATK NTRK3 RYR1 PTP4A3 GRK2 GRK3 PRKACA PRKACG PRKCE NOS2	5.94e-07	171	168	10	CID000003894
Drug	NPC 15437	GRIA1 GRK2 GRK3 PRKACA PRKACG PRKCE	1.08e-06	46	168	6	CID000004548
Drug	Starlicide	NTRK3 GRK2 GRK3 PRKACA PRKACG PYGL	1.59e-06	49	168	6	CID000007255
Drug	Indomethacin [53-86-1]; Up 200; 11.2uM; MCF7; HT_HG-U133A	RPS6KA2 F5 RYR1 CFLAR NEK1 MTA1 LRP6 PRKCE SMPD2 ENO3	1.96e-06	195	168	10	5468_UP
Drug	2',3'-dideoxyadenosine	ENOSF1 PKDREJ GRK2 GRK3 PRKACA PRKACG PYGL	2.51e-06	82	168	7	CID000020039
Drug	8-N3cAMP	GRK2 GRK3 PRKACA PRKACG	2.70e-06	14	168	4	CID006426627
Drug	8-(6-aminohexyl)amino cyclic AMP	GRK2 GRK3 PRKACA PRKACG	2.70e-06	14	168	4	CID000161999
Drug	NA-382	GRK2 GRK3 PRKACA PRKACG	3.66e-06	15	168	4	CID000132534
Drug	AC1Q6RZ4	HK2 RYR1 GRK2 GRK3 PRKACA PRKACG PYGL ENO3	3.73e-06	123	168	8	CID000000719
Drug	isoquinolinium	SLC6A2 GRK2 GRK3 PRKACA PRKACG PRKCE EIF2AK1	5.84e-06	93	168	7	CID000008405
Drug	Florisil	MAK CILK1 SARS2 GRK2 GRK3 PRKACA PRKACG PRKCE	7.04e-06	134	168	8	CID000026924
Drug	BiM4	AVPR1A RPS6KA2 CFLAR GRK2 GRK3 PRKACA PRKACG PRKCE EEF2K SMPD2 NOS2	8.67e-06	283	168	11	CID000002399
Drug	AC1L1GTT	GRIA1 RYR1 SLC6A2 CFLAR GRK2 GRK3 PRKACA PRKACG PRKCE EEF2K	9.52e-06	233	168	10	CID000003837
Drug	8-pCPT-cGMP	GRK2 GRK3 NRK PRKACA PRKACG NOS2	1.01e-05	67	168	6	CID000123969
Drug	8-azidoadenosine	GRK2 GRK3 PRKACA PRKACG	1.02e-05	19	168	4	CID000160751
Drug	8-thiomethyl-cAMP	GRK2 GRK3 PRKACA PRKACG	1.02e-05	19	168	4	CID000093140
Drug	8-chloroadenosine	GRK2 GRK3 NRK PRKACA PRKACG	1.10e-05	40	168	5	CID000147569
Drug	KT5720	NTRK3 GRIA1 GRK2 GRK3 PRKACA PRKACG PRKCE AKAP13 NOS2	1.18e-05	189	168	9	CID000003844
Drug	AC1L19C4	HK2 GRK2 GRK3 PRKACA PRKACG PYGL	1.20e-05	69	168	6	CID000000483
Drug	DiC8	AVPR1A PTP4A3 GRK2 GRK3 PRKACA PRKACG PRKCE NOS2	1.32e-05	146	168	8	CID000001323
Drug	Furosemide [54-31-9]; Up 200; 12uM; PC3; HT_HG-U133A	WSB1 MAK DDX60 CNMD CHRNA2 SLC3A1 CFLAR SHANK2 PRKACG	1.39e-05	193	168	9	4503_UP
Drug	arabinosyladenine	HK2 PDGFRB POLR2A NT5C3B LARS2 F5 F8 RYR1 BPNT1 GRK2 GRK3 TBK1 PRKACA PRKACG NKPD1 PYGL PRKCE NOS2	1.44e-05	762	168	18	CID000000191
Drug	magnesium	DNAH3 RFK HK2 MATK POLR2A COPB2 GRIA1 NT5C3B DPM1 RYR1 BPNT1 GRK2 GRK3 TBK1 PRKACA PRKACG MTR NKPD1 PRKCE SMPD2 EIF2AK1 ENO3 NOS2 ALK DNAH11	1.45e-05	1325	168	25	CID000000888
Drug	16-phenyl tetranor Prostaglandin E2; Down 200; 10uM; MCF7; HT_HG-U133A	ABCA2 TMEM45A PLXDC1 SH3BP2 ZKSCAN5 F8 CFLAR GRK3 SOAT2	1.57e-05	196	168	9	7541_DN
Drug	milrinone	PLCXD1 GRK2 GRK3 PRKACA PRKACG SMPD2 NUDT15 NOS2	1.61e-05	150	168	8	CID000004197
Drug	Loracarbef [121961-22-6]; Down 200; 10.8uM; MCF7; HT_HG-U133A	GCNT1 ZKSCAN5 CFLAR PTP4A3 MTA1 GRK2 GRK3 PCIF1 SEMA4A	1.64e-05	197	168	9	3532_DN
Drug	Ofloxacin [82419-36-1]; Down 200; 11uM; MCF7; HT_HG-U133A	ABCA2 MATK SH3BP2 NEK1 PTP4A3 SHANK2 UGGT2 AKAP13 KEL	1.64e-05	197	168	9	2302_DN
Drug	Clindamycin hydrochloride [21462-39-5]; Up 200; 8.6uM; PC3; HT_HG-U133A	CUL3 ZBTB20 PLXND1 ZKSCAN5 PTP4A3 MTA1 GRK2 SMPD2 LARGE1	1.70e-05	198	168	9	2057_UP
Drug	vanadyl	DNAH3 PDGFRB DPM1 PTP4A3 GRK2 GRK3 PRKACA PRKACG LRP6 PRKCE DNAH11	1.85e-05	307	168	11	CID000061671
Drug	Sp-8-Cl-cAMPS	GRK2 GRK3 PRKACA PRKACG	1.89e-05	22	168	4	CID000133987
Drug	orthovanadate	DNAH3 RFK PDGFRB RYR1 GRK2 GRK3 TBK1 PRKACA PRKACG NKPD1 PYGL PRKCE DNAH11	2.20e-05	435	168	13	CID000061672
Drug	4,4'-diisothiocyanostilbene-2,2'-disulfonic acid	RNF112 F8 SLC26A8 GRK2 GRK3 SLC13A1 PRKACA PRKACG SLC13A5	2.33e-05	206	168	9	CID000040600
Drug	AC1Q6RZL	HK2 SLC3A1 PRKACA PRKACG PYGL	2.46e-05	47	168	5	CID000001144
Drug	noradrealine	PLCXD1 COX6A1 ZNF699 CHRNA2 RYR1 HSPA13 SLC6A2 GRK2 GRK3 SHANK2 PRKACA PRKACG PYGL PRKCE NOS2	2.50e-05	575	168	15	CID000000951
Drug	DPCPX	ZDHHC4 GRK2 GRK3 PRKACA PRKACG PRKCE NOS2	2.64e-05	117	168	7	CID000001329
Drug	allulose 6-phosphate	HK2 PTPN5 GRK2 GRK3 PRKACA PRKACG PYGL ENO3	2.80e-05	162	168	8	CID000000603
Drug	propanoyl	RNF112 RYR1 SOAT2	3.21e-05	9	168	3	CID000139982
Drug	Phosphoryl	RFK HK2 RPS6KA2 GLYCTK PTPN5 GRK2 GRK3 PRKACA PRKACG	3.26e-05	215	168	9	CID006857426
Drug	H 85	GRK2 GRK3 PRKACA PRKACG	3.77e-05	26	168	4	CID006439306
Drug	7B-forskolin	GRK2 GRK3 PRKACA PRKACG	3.77e-05	26	168	4	CID000130638
Drug	Kemptide	RPS6KA2 GRK2 GRK3 PRKACA PRKACG PRKCE AKAP13	3.83e-05	124	168	7	CID000100074
Drug	K 252	NTRK3 GRK2 GRK3 PRKACA PRKACG PRKCE	4.85e-05	88	168	6	CID000003813
Drug	H-9 dihydrochloride	RNF112 GRK2 GRK3 PRKACA PRKACG PRKCE	5.51e-05	90	168	6	CID000003544
Drug	1,3-diolein	GRK2 GRK3 PRKACA PRKACG PRKCE SMPD2	5.51e-05	90	168	6	CID000033120
Drug	KN-62	AVPR1A GRIA1 PTP4A3 GRK2 GRK3 PRKACA PRKACG PRKCE EEF2K	5.51e-05	230	168	9	CID000003838
Drug	Mesotocin	AVPR1A ZNF699 SHANK2 MTR	5.88e-05	29	168	4	CID000123799
Drug	trapidil	PDGFRB GRK2 GRK3 PRKACA PRKACG	6.33e-05	57	168	5	CID000005531
Drug	AC1O5WLA	GRK2 GRK3 PRKACA PRKACG	6.75e-05	30	168	4	CID006442113
Drug	2,3-DPG	HK2 NT5C3B GRK2 GRK3 PRKACA PRKACG ENO3	7.23e-05	137	168	7	CID000000061
Drug	Ro-31-8425	GRK2 GRK3 PRKACA PRKACG PRKCE	8.11e-05	60	168	5	CID000002404
Drug	glucose-6-P	HK2 PICALM SLC3A1 PTPN5 GRK2 GRK3 TSPAN31 NRK PRKACA PRKACG PYGL	9.09e-05	366	168	11	CID000000208
Drug	AC1L1G9T	PDGFRB MATK S100B PTP4A3 GRK2 GRK3 NRK PRKACA PRKACG PRKCE SMPD2 NOS2	9.40e-05	433	168	12	CID000003591
Drug	AC1L1GU8	GRK2 GRK3 PRKACA PRKACG NOS2	9.49e-05	62	168	5	CID000003843
Drug	N6-monobutyryl-cAMP	GRK2 GRK3 PRKACA PRKACG	9.90e-05	33	168	4	CID000115029
Drug	Famotidine [76824-35-6]; Up 200; 11.8uM; PC3; HG-U133A	ENOSF1 NTRK3 SH3BP2 PLXND1 CFLAR ZFHX4 TRMT1L EIF2AK1	1.04e-04	195	168	8	1946_UP
Drug	AC1LAIK6	PLXDC1 GRK2 GRK3 PRKACA PRKACG HSD11B1	1.05e-04	101	168	6	CID000469113
Drug	AMP group	HK2 NT5C3B LARS2 BPNT1 SARS2 GRK2 GRK3 STRADA PRKACA PRKACG PYGL PRKCE ENO3 NOS2	1.05e-04	579	168	14	CID000000224
Drug	triethyltin bromide	HK2 AKAP13 KEL	1.07e-04	13	168	3	CID000017701
Drug	geldanamicin	MAK HK2 MATK ZDHHC4 HSPA13 CFLAR GRK2 GRK3 EEF2K EIF2AK1 NOS2	1.07e-04	373	168	11	CID000003460
Drug	myo-inositol	PDGFRB AVPR1A TBL1Y INPP5A PLCXD1 MATK POLR2A NT5C3B CHRNA2 RYR1 BPNT1 GRK2 GRK3 NRK PRKACA PRKACG PRKCE	1.10e-04	811	168	17	CID000000892
Drug	Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; MCF7; HT_HG-U133A	GCNT1 F5 RYR1 SLC3A1 MTA1 PRKCE AKAP13 SMPD2	1.11e-04	197	168	8	7014_UP
Drug	Flufenamic acid [530-78-9]; Up 200; 14.2uM; MCF7; HT_HG-U133A	AVPR1A TBL1Y NSD2 RPS6KA2 CHRNA2 CFLAR KEL SEMA4A	1.11e-04	197	168	8	5478_UP
Drug	Lithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A	CUL3 DNAH3 CFLAR TSPAN31 PRKACA LRP6 AKAP13 SMPD2	1.11e-04	197	168	8	3433_DN
Drug	novobiocin sodium, USP; Up 200; 100uM; MCF7; HG-U133A	ENOSF1 WSB1 DNAH3 GCNT1 ZKSCAN5 F8 PRKACA AKAP13	1.15e-04	198	168	8	437_UP
Drug	Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	ABCA2 TBL1Y F5 ZKSCAN5 RYR1 CFLAR PTP4A3 AKAP13	1.15e-04	198	168	8	1689_UP
Drug	fura 2	AVPR1A RYR1 TBK1 PRKCE SMPD2	1.19e-04	65	168	5	CID000057054
Drug	Chenodiol [474-25-9]; Down 200; 10.2uM; HL60; HT_HG-U133A	SH3BP2 F5 PTP4A3 MTA1 LRP6 AKAP13 ALK ADGRL3	1.19e-04	199	168	8	2402_DN
Drug	Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; MCF7; HT_HG-U133A	DNAH3 ABCA2 SH3BP2 CFLAR MTA1 GRK3 AKAP13 SEMA4A	1.19e-04	199	168	8	3435_DN
Drug	C070379	HK2 RYR1 GRK2 GRK3 PRKACA PRKACG AKAP13 NOS2	1.19e-04	199	168	8	CID003034747
Drug	Bay K 8644	RYR1 GRK2 GRK3 PRKACA PRKACG PRKCE EEF2K	1.28e-04	150	168	7	CID000002303
Drug	MDL-12330A	RNF112 GRK2 GRK3 PRKACA PRKACG	1.28e-04	66	168	5	CID000004024
Drug	LY83583	SLC3A1 GRK2 GRK3 PRKACA PRKACG NOS2	1.30e-04	105	168	6	CID000003976
Drug	fasudil	GRK2 GRK3 PRKACA PRKACG MTR PRKCE NOS2	1.33e-04	151	168	7	CID000003547
Drug	8-Cl-cAMP	GRK2 GRK3 NRK PRKACA PRKACG	1.38e-04	67	168	5	CID000100299
Drug	Tannins	GRK2 GRK3 PRKACA PRKACG	1.40e-04	36	168	4	CID000250395
Drug	phosphine oxide	RYR1 GRK2 GRK3 PRKACA PRKACG PRKCE	1.44e-04	107	168	6	CID000166931
Drug	Boc-leu-ser-thr-arg-mca	F5 F8	1.62e-04	3	168	2	CID000189792
Drug	I-Q-S	WSB1 GRK2 GRK3 PRKACA PRKACG PRKCE HSD11B1	1.63e-04	156	168	7	CID000003540
Drug	8-Br	RYR1 GRK2 GRK3 PRKACA PRKACG PRKCE NOS2	1.63e-04	156	168	7	CID000168120
Drug	phenylisopropyladenosine	GRK2 GRK3 PRKACA PRKACG PRKCE	1.69e-04	70	168	5	CID000005022
Drug	Pc 12	NTRK3 CHRNA2 GRK2 GRK3 PRKACA PRKACG PRKCE SMPD2	1.78e-04	211	168	8	CID003036508
Drug	sulprostone	PLCXD1 GRK2 GRK3 PRKACA PRKACG	1.81e-04	71	168	5	CID005312153
Drug	forskolin from Coleus forskohlii	PDGFRB AVPR1A TBL1Y PLCXD1 GRIA1 CHRNA2 RYR1 PTPN5 MTA1 GRK2 GRK3 NRK EIF2B5 PRKACA PRKACG PRKCE AKAP13 EIF2AK4 NOS2	1.82e-04	1013	168	19	CID000003413
Drug	dihydrochloride	GRK2 GRK3 PRKACA PRKACG PRKCE SMPD2 NOS2	1.83e-04	159	168	7	CID000070978
Drug	calmidazolium chloride	GRK2 GRK3 PRKACA PRKACG PRKCE EEF2K NOS2	1.90e-04	160	168	7	CID000002531
Drug	2-(aminomethyl)pyrrolidine	HK2 PLCXD1 GRK2 GRK3 PRKACA PRKACG NOS2	1.98e-04	161	168	7	CID000072032
Drug	1d3q	GRK2 GRK3 PRKACA PRKACG	2.12e-04	40	168	4	CID000001635
Disease	Infiltrating duct carcinoma of female breast	MAK ATR PDGFRB NRK	4.87e-06	21	162	4	C3165106
Disease	Adenocarcinoma of large intestine	MATK RPS6KA2 GRK2 NRK TBK1 EEF2K	1.54e-05	96	162	6	C1319315
Disease	Adenocarcinoma of lung (disorder)	HK2 NOP56 ATR NTRK3 NEK1 EIF2B5 EIF2AK1 ALK	1.94e-05	206	162	8	C0152013
Disease	Mental Depression	GRIA1 CHRNA2 SLC6A2 S100B MTR HSD11B1 NOS2 ALK	8.53e-05	254	162	8	C0011570
Disease	hepatitis (biomarker_via_orthology)	F5 NOS2	1.78e-04	4	162	2	DOID:2237 (biomarker_via_orthology)
Disease	Depressive disorder	GRIA1 CHRNA2 SLC6A2 S100B MTR HSD11B1 NOS2 ALK	2.07e-04	289	162	8	C0011581
Disease	Kohlschutter-Tonz syndrome (implicated_via_orthology)	SLC13A1 SLC13A5	2.96e-04	5	162	2	DOID:0111668 (implicated_via_orthology)
Disease	adenoid cystic carcinoma (is_implicated_in)	ATR NTRK3	2.96e-04	5	162	2	DOID:0080202 (is_implicated_in)
Disease	Bipolar Disorder	RPS6KA2 GRIA1 LARS2 RFX4 CHRNA2 SLC6A2 S100B GRK3 SHANK2 MTR	3.22e-04	477	162	10	C0005586
Disease	Schizophrenia	ADAMTS3 PDGFRB AVPR1A INPP5A NTRK3 GRIA1 LARS2 SLC6A2 PTPN5 S100B SLC26A8 NRXN2 MTR ALK	3.85e-04	883	162	14	C0036341
Disease	portal hypertension (is_marker_for)	AVPR1A F5	4.43e-04	6	162	2	DOID:10762 (is_marker_for)
Disease	hypertension (is_implicated_in)	AVPR1A SLC6A2 MTR HSD11B1 NOS2	5.58e-04	121	162	5	DOID:10763 (is_implicated_in)
Disease	Manic Disorder	RPS6KA2 S100B GRK3 SHANK2	6.39e-04	71	162	4	C0024713
Disease	Large cell carcinoma of lung	ATR NTRK3 NEK1	7.17e-04	32	162	3	C0345958
Disease	alcohol use disorder (implicated_via_orthology)	EPS8L2 CHRNA2 RYR1 PRKACA PRKACG PRKCE	7.51e-04	195	162	6	DOID:1574 (implicated_via_orthology)
Disease	androsterone sulfate measurement	NTRK3 ZKSCAN5 ALK	7.85e-04	33	162	3	EFO_0021117
Disease	Vasogenic Brain Edema	S100B NOS2	8.21e-04	8	162	2	C0750969
Disease	Cytotoxic Brain Edema	S100B NOS2	8.21e-04	8	162	2	C0750970
Disease	alcohol-related neurodevelopmental disorder (implicated_via_orthology)	SLC13A1 SLC13A5	8.21e-04	8	162	2	DOID:0050667 (implicated_via_orthology)
Disease	Cytotoxic Cerebral Edema	S100B NOS2	8.21e-04	8	162	2	C0472388
Disease	Vasogenic Cerebral Edema	S100B NOS2	8.21e-04	8	162	2	C0472387
Disease	Brain Edema	S100B NOS2	8.21e-04	8	162	2	C1527311
Disease	Cerebral Edema	S100B NOS2	8.21e-04	8	162	2	C0006114
Disease	Manic	RPS6KA2 S100B GRK3 SHANK2	9.11e-04	78	162	4	C0338831
Disease	Depression, Bipolar	RPS6KA2 S100B GRK3 SHANK2	9.55e-04	79	162	4	C0005587
Disease	Recurrent depression	SLC6A2 S100B	1.05e-03	9	162	2	C0221480
Disease	macrovascular complications of diabetes	RPS6KA2 F5	1.31e-03	10	162	2	EFO_0010977
Disease	hyperhomocysteinemia (implicated_via_orthology)	GRIA1 F8	1.59e-03	11	162	2	DOID:9279 (implicated_via_orthology)
Disease	hypertension (biomarker_via_orthology)	HK2 PDGFRB AVPR1A GRK2 GRK3 NOS2	1.64e-03	227	162	6	DOID:10763 (biomarker_via_orthology)
Disease	Myocardial Infarction	F5 S100B PRKCE NOS2	1.89e-03	95	162	4	C0027051
Disease	N-acetylputrescine measurement	SLC6A2 TUBGCP6	1.91e-03	12	162	2	EFO_0800127
Disease	Congenital muscular dystrophy	RYR1 LARGE1	1.91e-03	12	162	2	cv:C0699743
Disease	Childhood Ataxia with Central Nervous System Hypomyelinization	EIF2B5 MTR	2.61e-03	14	162	2	C1858991
Disease	Impaired cognition	PICALM EIF2B5	2.61e-03	14	162	2	C0338656
Disease	hepatic encephalopathy (biomarker_via_orthology)	GRIA1 NOS2	3.00e-03	15	162	2	DOID:13413 (biomarker_via_orthology)
Disease	corneal topography	ADAMTS3 ADAMTS6 AKAP13 EIF2AK4	3.11e-03	109	162	4	EFO_0004345
Disease	Intellectual Disability	IQSEC3 PDGFRB NSD2 GRIA1 PTPN23 SHANK2 NRXN2 LARGE1	3.39e-03	447	162	8	C3714756
Disease	interferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement	PDGFRB F5	3.42e-03	16	162	2	EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Disease	hyperglycemia (implicated_via_orthology)	HK2 GRK2	3.86e-03	17	162	2	DOID:4195 (implicated_via_orthology)
Disease	unipolar depression, response to bupropion, mood disorder	CUL3 ADAMTS6	4.82e-03	19	162	2	EFO_0003761, EFO_0004247, EFO_0006326

Protein segments in the cluster

Peptide	Gene	Start	Entry
KVFHPNIHIVSNYMD	NT5C3B	171	Q969T7
FYATEIILGLEHMHN	GRK3	296	P35626
KHCGEVMIFELAYHV	EIF2AK4	116	Q9P2K8
QVFEGHTHYVMQIVI	COPB2	136	P35606
QTVGHHAIDLYAEAM	DPH6	51	Q7L8W6
SGFDVLYHNMKHGQI	FCHO2	16	Q0JRZ9
LYHNMKHGQISTKEL	FCHO2	21	Q0JRZ9
VLFVSVGSMVEHYHT	SH3BP2	526	P78314
EFHHVRTLKIMSGVY	AKAP13	2006	Q12802
LGIALYKMFHHTAIL	ADGRL3	1026	Q9HAR2
AYMGHIEVVKLLVSH	ANKRD28	181	O15084
QYGHMQVVETLLKHG	ANKRD29	121	Q8N6D5
AEFMKHFLLYGHAVS	DNAH11	1046	Q96DT5
MQKALEGVHYIADHL	CHRNA2	466	Q15822
AYHLAKMGAHVVVTA	HSD11B1	51	P28845
KALVTGYFMQVAHLE	DHX15	691	O43143
QYHKDVKHMNSAGVL	BPNT1	271	O95861
YEVQKFLHLSMHGIS	CFLAR	276	O15519
AYIHGMKHATGNYII	DPM1	101	O60762
HGRKDIEHYILSVMN	ADAMTS6	266	Q9UKP5
FYAAEIILGLEHMHN	GRK2	296	P25098
GSFHLIHLMFDDYVL	RFX4	451	Q33E94
ELYIGHHGEKMLESF	ADAMTS19	386	Q8TE59
YSGVENKQVVIIHHM	INTS4	711	Q96HW7
VQMKIYYFAAVAHLH	PTPN23	241	Q9H3S7
QFVHHVMSLYEKQLS	PTPN5	546	P54829
LVETYGKIMNHEDHL	CDC42BPG	281	Q6DT37
VFYSALHCNIMHKGV	OOSP3	91	A0A2R8YFM6
EMAQKGVLHAVHTAY	NOS2	1031	P35228
FVGTLKMGHRHQYQE	OTUD7B	611	Q6GQQ9
LLYFIHVMDHIAVKE	GDAP2	371	Q9NXN4
HVMDHIAVKEYVLVY	GDAP2	376	Q9NXN4
KAHSFLMDFIHQVGL	NUP133	606	Q8WUM0
HIMEGVYSELHSVVA	PAN2	56	Q504Q3
MVLLHVLFEHAVGYA	NOP56	1	O00567
GRVMLVKHKETGNHY	PRKACA	56	P17612
EVLMSRHNVGYHIVY	LARGE1	521	O95461
LHQGLYIVMEHVSKG	MATK	296	P42679
QHLYAKILHLVMADG	NEK1	1236	Q96PY6
HYVTILMKGEVDVTH	NUDT15	91	Q9NV35
GMVYLASQHFVHRDL	NTRK3	666	Q16288
QYHGFVVIHGTDTMA	ASPG	106	Q86U10
NHIYHMIKLGLGTDE	HSP90AB3P	551	Q58FF7
VTSALMFLHQHGVIY	PRKCE	516	Q02156
VYIHHFDRIAQMGSE	MOB3A	166	Q96BX8
IGYHHSAMSFKEKQL	DDX60	1261	Q8IY21
HNKIYAIPQEVMHGT	HK2	556	P52789
QIHMHVTAKEYGARV	EIF2B5	286	Q13144
LHEHFKYPVMIQRAS	ENOSF1	391	Q7L5Y1
EMGVHTVSVKYRGQH	FLNB	2161	O75369
VALHGKLEYYTDIMH	PLXNB2	1356	O15031
VTVAYGEPVHHVMQF	PLXND1	511	Q9Y4D7
EFYQVVHTHKPHFMA	INPP5A	36	Q14642
YVPIITLAAMHHFAK	OR51A7	251	Q8NH64
VSHVGAVAFFYIHML	OR51F1	251	A6NGY5
FHYIMKYGVHVKQVT	ENPP5	51	Q9UJA9
IKHAHENDITHFYML	NSD2	1106	O96028
VLHFYHTGKLHVMAE	KCNS2	81	Q9ULS6
AGIGHAMVNKLHYLV	NRXN2	386	Q9P2S2
KVYGHNVISHKGMIY	KLHL41	436	O60662
GHLDYVMDILVFHSS	LRP6	871	O75581
VTLAIYHVHHKMTAN	LAMP5	251	Q9UJQ1
HEMQHFVKVIQGYIA	TUBGCP6	1671	Q96RT7
ISSHQHDGMEAYVKV	F8	331	P00451
AYMGHLDVVALLINH	ANKRD44	181	Q8N8A2
AVSMLNVYLKSHHGE	COX6A1	51	P12074
VQVISAMAHHGYLEQ	MROH1	411	Q8NDA8
HNLGMYVFLHAVKGT	ORMDL1	56	Q9P0S3
VVIFYHKGEYHAMDI	RFESD	41	Q8TAC1
QIEMLEHKYGGHLVS	IQSEC3	301	Q9UPP2
LEGSEKNLHFVHMVY	PLCXD1	111	Q9NUJ7
KNLHFVHMVYTTALV	PLCXD1	116	Q9NUJ7
QYHVQHLATFIMDKS	EPS8L2	51	Q9H6S3
NVAHKYTMEHFIEVI	KLHL4	301	Q9C0H6
VMLTVFKHNHGAYQF	NAA40	171	Q86UY6
EVKHLGYASHLMEIF	IL20RA	356	Q9UHF4
SGMVLNAYVTHLHAE	SMPD2	126	O60906
NLIYMGHVKGYISHQ	PCID2	366	Q5JVF3
EHLGFLQKLYAAMHE	ATR	1671	Q13535
DQIIHYHGVVKSMLG	ATR	1731	Q13535
FHGKEHVQNYLLTLM	ADAMTS3	271	O15072
FHVILTEMANKHFGI	DNAH6	2346	Q9C0G6
VRHQETGGHYAMKIL	PRKACG	61	P22612
MHYKAVHNTAVLFLQ	PCIF1	631	Q9H4Z3
VKSMAQFYGLLAHVA	GLYCTK	341	Q8IVS8
QHHYDYGMRAVKSVL	DNAH3	1596	Q8TD57
LVEGVFYIHNMGIVH	EIF2AK1	426	Q9BQI3
GISHVELNVMMHFIY	BTBD8	251	Q5XKL5
ELYRNAYTMVLHKHG	CUL3	56	Q13618
LKYGQVLMHSHVVII	ABCA2	771	Q9BZC7
EVGHSMAFRVHLFYK	AREL1	71	O15033
AAAGAYVHMVTHFIQ	TMBIM6	41	P55061
YVHMVTHFIQAGLLS	TMBIM6	46	P55061
MYQILQGLAFIHKHG	MAK	106	P20794
IYAAFKEVLGSGMHH	IFRD2	431	Q12894
AAAMAYGLHKADVFH	HSPA13	206	P48723
AMRIGAEVYHHLKGV	ENO3	181	P13929
SILGKVHLAMVRYHE	EEF2K	521	O00418
DHIYNVIVTAHAFVM	MT-CO1	51	P00395
DQTYAKIHFTIMFIG	MT-CO1	406	P00395
FPIAYSIVVHHKIEM	GCNT1	121	Q02742
RTNYTLHVIEMKHDG	GRIA1	361	P42261
SEIAVGHQYKHQGMF	SLC25A35	136	Q3KQZ1
NAIVFSYGHLKVIDM	SLC13A1	536	Q9BZW2
NAIVFTYGHLKVADM	SLC13A5	511	Q86YT5
AFTTKGNLKVHYMTH	SALL4	906	Q9UJQ4
VHLGHAIMSFYAALI	RYR1	2416	P21817
GIHSVYTVYQGHEIM	GARNL3	261	Q5VVW2
QYQKGHTLAILHEML	IFNE	71	Q86WN2
VKVAEAGHYTMRAFH	PDGFRB	386	P09619
HHSRVYFMTLGKLEE	NRK	1561	Q7Z2Y5
GLYRVHHFTKVEMFG	SARS2	341	Q9NP81
IFSILGYMAHEHKVN	SLC6A2	361	P23975
YMNISFHVGNHVLSE	RNF133	41	Q8WVZ7
LQGVLKALDYIHHMG	STRADA	176	Q7RTN6
IIGEQITSKMGAHYH	TRMT1L	171	Q7Z2T5
SVFLTEEGYLHIQMH	SEL1L3	321	Q68CR1
EEGYLHIQMHLVKGE	SEL1L3	326	Q68CR1
VIGYEKMIHHPHFSV	PRSS58	81	Q8IYP2
LYIGGKEHAVMHLFY	LARS2	556	Q15031
VDYGNKSHVDLHLLM	TDRD9	981	Q8NDG6
KSHEFHAINGMIYSL	F5	1801	P12259
LMAVYSVGKHLFVSQ	NKPD1	171	Q17RQ9
MAVTTIILQAFGKYH	TMEM184A	196	Q6ZMB5
VHTIILDFSMVHYVD	SLC26A8	721	Q96RN1
VTEYMLQKHVQLTHD	PRDM15	1206	P57071
GIHLHTHYVMAKVIV	PKDREJ	1151	Q9NTG1
REAMHGVFLYHAIKS	MTR	591	Q99707
AHKHTAVLVDGMLYS	SEMA4A	181	Q9H3S1
KAMVALIDVFHQYSG	S100B	6	P04271
LYHDFTTTQVGMHDI	SLC3A1	346	Q07837
SYILVKIHVKNGDHM	WDR19	1156	Q8NEZ3
LFHAMDTLHKNIYDI	MTA1	251	Q13330
EVQHFRTIYHMFIAG	SOAT2	116	O75908
VQHLEHLLFYGADMS	SHANK2	311	Q9UPX8
KVMEGHGEVNIKHYL	ALK	971	Q9UM73
VFIGSHKRNHYMLLV	CD300LB	141	A8K4G0
MYQILQGLAFIHKHG	CILK1	106	Q9UPZ9
LKMAQGHRVETEHYE	NCAPH	531	Q15003
HIYNVHYTMSINGKL	CNMD	71	O75829
FKSLITTHHLMVYGN	PICALM	76	Q13492
MAHKYVGLQYHGSVT	ZNF30	1	P17039
TTVYNLKAHMKGHEQ	ZXDB	346	P98169
FPSMQELVAHSKLHY	ZNF414	156	Q96IQ9
HMQKYQLVAHIKEGG	ZFHX4	941	Q86UP3
EVSYKHMRFLITHNP	PTP4A3	11	O75365
GAVKHHQVLLFFYMI	TSPAN13	66	O95857
LEMFVHVAEVMGKHY	RNF112	291	Q9ULX5
YAMKISHQDFHGNIL	PLEKHD1	101	A6NEE1
SDLHLQTGYKVERHM	POLR2A	436	P24928
HTFIVLHLVLQGMVY	ZDHHC4	66	Q9NPG8
HLHVMDTVFLIQYLF	ZDHHC4	236	Q9NPG8
GAVNHHQVLLFFYMI	TSPAN31	66	Q12999
MQASHGETFHVLYLT	SEMA7A	416	O75326
HIMHTFKEDFYGEIL	RFK	81	Q969G6
HTLMKHQEPVYSVAF	TBL1Y	446	Q9BQ87
YISHLESHLGFQMKD	TSHZ2	941	Q9NRE2
VVKHLQVFGMFASAY	AVPR1A	126	P37288
MKIHYQVHLVVHTGE	ZNF234	411	Q14588
QNYVKHMFVHTGEKP	ZBTB20	591	Q9HC78
LIKHMVTHTGVRAYQ	ZBTB20	621	Q9HC78
VKAYLMVHQKTHTGE	ZNF25	241	P17030
FTTVYNLKAHMKGHE	ZXDA	341	P98168
IHFLKYFSVHKGQNM	WDR93	461	Q6P2C0
VIGHMAYNSVEVHQI	SLC9C2	66	Q5TAH2
HHDGRIVFAYKEIPM	PLXDC1	226	Q8IUK5
YTMIRKLEGHHHDVV	WSB1	246	Q9Y6I7
VDTIVMAHHGYFQLK	UGGT2	1121	Q9NYU1
FRAHMKIHIGKTNYE	ZNF699	266	Q32M78
VMLENYSHLVSVGHL	ZNF674	36	Q2M3X9
EFMLPVHFYGKVEHT	PYGL	196	P06737
FIFYNHTHGREMLDI	TMEM45A	136	Q9NWC5
QSMVHAGSFHILVVY	WDR87	71	Q6ZQQ6
CFIYDLSAVVMHHGK	USP44	616	Q9H0E7
IRHHLMDKQGVYVTS	VPS37A	86	Q8NEZ2
IHVFSLQQMTAHKIY	TBK1	311	Q9UHD2
FQYVSLIEHQVLHMG	ZKSCAN5	671	Q9Y2L8
SHFIQHGGKMFVYLE	ZNF554	286	Q86TJ5
GSIMAHELLHIFYQL	KEL	576	P23276
ITKTMDYLHSQGVVH	RPS6KA2	516	Q15349
QDVHLVKGAMAATYF	RPS6KA2	686	Q15349