Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmismatched DNA binding

PMS2 MLH3 MUTYH

8.71e-0614593GO:0030983
GeneOntologyMolecularFunctionMutSalpha complex binding

PMS2 MUTYH

1.79e-047592GO:0032407
GeneOntologyMolecularFunctionmismatch repair complex binding

PMS2 MUTYH

4.64e-0411592GO:0032404
DomainMutL_C

PMS2 MLH3

9.48e-062582PF08676
DomainMutL_C

PMS2 MLH3

9.48e-062582SM00853
DomainMutL_C

PMS2 MLH3

9.48e-062582IPR014790
DomainDNA_mismatch_repair_C

PMS2 MLH3

5.66e-054582IPR013507
DomainDNA_mismatch_repair_fam

PMS2 MLH3

5.66e-054582IPR002099
DomainDNA_mis_repair

PMS2 MLH3

5.66e-054582PF01119
DomainDNA_MISMATCH_REPAIR_1

PMS2 MLH3

5.66e-054582PS00058
DomainDNA_mismatch_repair_CS

PMS2 MLH3

9.42e-055582IPR014762
DomainDi19_Zn_binding_dom

ZEB1 ZEB2

1.97e-047582IPR008598
Domainzf-Di19

ZEB1 ZEB2

1.97e-047582PF05605
DomainHomeodomain-like

ZEB1 RCOR3 POU3F4 RERE KDM1B ZEB2

5.61e-04332586IPR009057
DomainELM2

RCOR3 RERE

7.23e-0413582PF01448
DomainELM2

RCOR3 RERE

7.23e-0413582PS51156
DomainELM2_dom

RCOR3 RERE

7.23e-0413582IPR000949
DomainELM2

RCOR3 RERE

7.23e-0413582SM01189
DomainCNH

MAP4K3 CIT

8.42e-0414582SM00036
DomainCNH

MAP4K3 CIT

9.70e-0415582PF00780
DomainCNH

MAP4K3 CIT

9.70e-0415582PS50219
DomainCNH_dom

MAP4K3 CIT

9.70e-0415582IPR001180
DomainHATPase_c

PMS2 MLH3

1.40e-0318582SM00387
DomainHATPase_c

PMS2 MLH3

1.57e-0319582PF02518
DomainPWWP

PWWP2A NSD2

1.74e-0320582SM00293
DomainHATPase_C

PMS2 MLH3

1.92e-0321582IPR003594
DomainRibosomal_S5_D2-typ_fold_subgr

PMS2 MLH3

2.10e-0322582IPR014721
DomainPWWP

PWWP2A NSD2

2.30e-0323582PF00855
DomainPWWP_dom

PWWP2A NSD2

2.30e-0323582IPR000313
DomainPWWP

PWWP2A NSD2

2.50e-0324582PS50812
DomainTRYPSIN_SER

GZMB PRSS55 CORIN

2.76e-0390583IPR033116
DomainSANT_dom

RCOR3 RERE

2.94e-0326582IPR017884
DomainSANT

RCOR3 RERE

3.40e-0328582PS51293
DomainTRYPSIN_HIS

GZMB PRSS55 CORIN

4.03e-03103583IPR018114
DomainTRYPSIN_SER

GZMB PRSS55 CORIN

4.37e-03106583PS00135
DomainTRYPSIN_HIS

GZMB PRSS55 CORIN

4.49e-03107583PS00134
DomainRibosomal_S5_D2-typ_fold

PMS2 MLH3

4.99e-0334582IPR020568
DomainPeptidase_S1A

GZMB PRSS55 CORIN

5.23e-03113583IPR001314
DomainMyb_DNA-binding

RCOR3 RERE

5.28e-0335582PF00249
DomainTRYPSIN_DOM

GZMB PRSS55 CORIN

5.49e-03115583PS50240
DomainPH

ACAP1 DGKD PLEKHA6 CIT

5.57e-03229584PF00169
DomainTryp_SPc

GZMB PRSS55 CORIN

5.75e-03117583SM00020
DomainMYB_LIKE

RCOR3 RERE

6.20e-0338582PS50090
DomainTrypsin

GZMB PRSS55 CORIN

6.32e-03121583PF00089
DomainTrypsin_dom

GZMB PRSS55 CORIN

6.32e-03121583IPR001254
DomainPeptidase_S1_PA

GZMB PRSS55 CORIN

6.61e-03123583IPR009003
Domain-

ACAP1 MTM1 DGKD PLEKHA6 CIT

7.24e-033915852.30.29.30
Pubmed

TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.

RIF1 KIF23 NSD2 ATP2A2 ZEB2 PSRC1

3.60e-0810960633554859
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

RIF1 PMS2 KIF23 ZEB1 SMC6 KDM1B ATP2A2 DSN1

1.10e-0645360829656893
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

MYT1L PMS2 MAP4K3 TUT7 SMC6 DCAF17 HIPK2 RCOR3 KDM1B DEDD VPS13B

2.17e-061084601111544199
Pubmed

Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo.

GZMB PTPN22 RERE

2.19e-061560320410501
Pubmed

ZEBs: Novel Players in Immune Cell Development and Function.

ZEB1 ZEB2

2.93e-06260230956067
Pubmed

Prognostic significance of ZEB1 and ZEB2 in digestive cancers: a cohort-based analysis and secondary analysis.

ZEB1 ZEB2

2.93e-06260228416756
Pubmed

Zfhx1a and Zfhx1b mRNAs have non-overlapping expression domains during chick and mouse midgestation limb development.

ZEB1 ZEB2

2.93e-06260212609600
Pubmed

Expression of miRNAs and ZEB1 and ZEB2 correlates with histopathological grade in papillary urothelial tumors of the urinary bladder.

ZEB1 ZEB2

2.93e-06260224306957
Pubmed

Either ZEB1 or ZEB2/SIP1 can play a central role in regulating the Epstein-Barr virus latent-lytic switch in a cell-type-specific manner.

ZEB1 ZEB2

2.93e-06260220375168
Pubmed

Prognostic Significance of Zinc Finger E-Box-Binding Homeobox Family in Glioblastoma.

ZEB1 ZEB2

2.93e-06260229476046
Pubmed

Epithelial-mesenchymal transition and mesenchymal-epithelial transition via regulation of ZEB-1 and ZEB-2 expression in pancreatic cancer.

ZEB1 ZEB2

2.93e-06260222213144
Pubmed

Functional conservation of zinc-finger homeodomain gene zfh1/SIP1 in Drosophila heart development.

ZEB1 ZEB2

2.93e-06260216957952
Pubmed

Genetic evidence for the involvement of mismatch repair proteins, PMS2 and MLH3, in a late step of homologous recombination.

PMS2 MLH3

2.93e-06260233453991
Pubmed

The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2.

ZEB1 ZEB2

2.93e-06260237819755
Pubmed

Epithelial-mesenchymal transition transcription factor ZEB1/ZEB2 co-expression predicts poor prognosis and maintains tumor-initiating properties in head and neck cancer.

ZEB1 ZEB2

2.93e-06260222892238
Pubmed

The Zeb proteins δEF1 and Sip1 may have distinct functions in lens cells following cataract surgery.

ZEB1 ZEB2

2.93e-06260225082886
Pubmed

Complete reversal of epithelial to mesenchymal transition requires inhibition of both ZEB expression and the Rho pathway.

ZEB1 ZEB2

2.93e-06260220025777
Pubmed

Epidermal growth factor receptor and mutant p53 expand an esophageal cellular subpopulation capable of epithelial-to-mesenchymal transition through ZEB transcription factors.

ZEB1 ZEB2

2.93e-06260220424117
Pubmed

Phosphodiesterase 4D regulates baseline sarcoplasmic reticulum Ca2+ release and cardiac contractility, independently of L-type Ca2+ current.

PDE4D ATP2A2

2.93e-06260221903937
Pubmed

TMPRSS2/ERG promotes epithelial to mesenchymal transition through the ZEB1/ZEB2 axis in a prostate cancer model.

ZEB1 ZEB2

2.93e-06260221747944
Pubmed

The adaptive antioxidant response during fasting-induced muscle atrophy is oppositely regulated by ZEB1 and ZEB2.

ZEB1 ZEB2

2.93e-06260237948583
Pubmed

The role of epithelial-mesenchymal transition drivers ZEB1 and ZEB2 in mediating docetaxel-resistant prostate cancer.

ZEB1 ZEB2

2.93e-06260228133913
Pubmed

Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity.

ZEB1 ZEB2

2.93e-06260234550965
Pubmed

Human transcription factor protein interaction networks.

RIF1 KIF23 ZEB1 POLH HIPK2 PDCD11 RCOR3 RERE KDM1B ATP2A2 CIT ZEB2

4.97e-061429601235140242
Pubmed

A NOTCH3-mediated squamous cell differentiation program limits expansion of EMT-competent cells that express the ZEB transcription factors.

ZEB1 ZEB2

8.77e-06360221890822
Pubmed

TCF4 promotes colorectal cancer drug resistance and stemness via regulating ZEB1/ZEB2 expression.

ZEB1 ZEB2

8.77e-06360231933004
Pubmed

Down-regulation of miR-144 promotes thyroid cancer cell invasion by targeting ZEB1 and ZEB2.

ZEB1 ZEB2

8.77e-06360224968735
Pubmed

Expression of miR-9 and miR-200c, ZEB1, ZEB2 and E-cadherin in Non-Small Cell Lung Cancers in Iran.

ZEB1 ZEB2

8.77e-06360231244281
Pubmed

miR-144-3p inhibited the growth, metastasis and epithelial-mesenchymal transition of colorectal adenocarcinoma by targeting ZEB1/2.

ZEB1 ZEB2

8.77e-06360234226299
Pubmed

Ginsenoside Rg3 Inhibits Migration and Invasion of Nasopharyngeal Carcinoma Cells and Suppresses Epithelial Mesenchymal Transition.

ZEB1 MMP2

8.77e-06360230915362
Pubmed

miR-23a promotes the transition from indolent to invasive colorectal cancer.

PMS2 MLH3

8.77e-06360222628407
Pubmed

The potential role of regulator of G-protein signaling 16 in cell motility mediated by δEF1 family proteins.

ZEB1 ZEB2

8.77e-06360226823172
Pubmed

A miRNA signature associated with human metastatic medullary thyroid carcinoma.

ZEB1 ZEB2

8.77e-06360224127332
Pubmed

p53 regulates epithelial-mesenchymal transition through microRNAs targeting ZEB1 and ZEB2.

ZEB1 ZEB2

8.77e-06360221518799
Pubmed

miR-139-5p suppresses cancer cell migration and invasion through targeting ZEB1 and ZEB2 in GBM.

ZEB1 ZEB2

8.77e-06360225833697
Pubmed

A novel interaction between human DNA polymerase eta and MutLalpha.

PMS2 POLH

8.77e-06360219703417
Pubmed

miR-139-5p inhibits epithelial-mesenchymal transition, migration and invasion of hepatocellular carcinoma cells by targeting ZEB1 and ZEB2.

ZEB1 ZEB2

8.77e-06360226022123
Pubmed

An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition.

ZEB1 ZEB2

8.77e-06360221411626
Pubmed

Langerhans cell maturation is accompanied by induction of N-cadherin and the transcriptional regulators of epithelial-mesenchymal transition ZEB1/2.

ZEB1 ZEB2

8.77e-06360224165969
Pubmed

Vimentin, zeb1 and Sip1 are up-regulated in triple-negative and basal-like breast cancers: association with an aggressive tumour phenotype.

ZEB1 ZEB2

8.77e-06360223412770
Pubmed

Src promotes EGF-induced epithelial-to-mesenchymal transition and migration in gastric cancer cells by upregulating ZEB1 and ZEB2 through AKT.

ZEB1 ZEB2

8.77e-06360229052277
Pubmed

Contributions by MutL homologues Mlh3 and Pms2 to DNA mismatch repair and tumor suppression in the mouse.

PMS2 MLH3

8.77e-06360216204034
Pubmed

Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-beta.

ZEB1 ZEB2

8.77e-06360217615296
Pubmed

miR-590-3p suppresses cancer cell migration, invasion and epithelial-mesenchymal transition in glioblastoma multiforme by targeting ZEB1 and ZEB2.

ZEB1 ZEB2

8.77e-06360226556542
Pubmed

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1.

ZEB1 ZEB2

8.77e-06360218376396
Pubmed

The miR-200 family inhibits epithelial-mesenchymal transition and cancer cell migration by direct targeting of E-cadherin transcriptional repressors ZEB1 and ZEB2.

ZEB1 ZEB2

8.77e-06360218411277
Pubmed

BMP4 signaling mediates Zeb family in developing mouse tooth.

ZEB1 ZEB2

8.77e-06360222350174
Pubmed

miR-200c inhibits TGF-β-induced-EMT to restore trastuzumab sensitivity by targeting ZEB1 and ZEB2 in gastric cancer.

ZEB1 ZEB2

8.77e-06360229302045
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PWWP2A RIF1 KIF23 NSD2 POLH SMC6 KDM1B ZEB2

9.58e-0660860836089195
Pubmed

Maternal DNA Methylation Regulates Early Trophoblast Development.

ZEB1 PLEKHA6 ZEB2

1.55e-052860326812015
Pubmed

Synaptotagmin gene content of the sequenced genomes.

SYT14 SYT14P1

1.75e-05460215238157
Pubmed

An intact Pms2 ATPase domain is not essential for male fertility.

PMS2 MLH3

1.75e-05460226753533
Pubmed

Screening methylation of DNA repair genes in the oral mucosa of chronic smokers.

PMS2 MLH3

1.75e-05460229775861
Pubmed

Fra-1/AP-1 induces EMT in mammary epithelial cells by modulating Zeb1/2 and TGFβ expression.

ZEB1 ZEB2

1.75e-05460225301070
Pubmed

miR-200b regulates cell migration via Zeb family during mouse palate development.

ZEB1 ZEB2

1.75e-05460222261924
Pubmed

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

ZEB1 ZEB2

1.75e-05460217360662
Pubmed

Downregulated microRNA-200a promotes EMT and tumor growth through the wnt/β-catenin pathway by targeting the E-cadherin repressors ZEB1/ZEB2 in gastric adenocarcinoma.

ZEB1 ZEB2

1.75e-05460223381389
Pubmed

Ets1 and ESE1 reciprocally regulate expression of ZEB1/ZEB2, dependent on ERK1/2 activity, in breast cancer cells.

ZEB1 ZEB2

1.75e-05460228247944
Pubmed

Complementary expression pattern of Zfhx1 genes Sip1 and deltaEF1 in the mouse embryo and their genetic interaction revealed by compound mutants.

ZEB1 ZEB2

1.75e-05460216598713
Pubmed

MiR-525-5p Repressed Metastasis and Anoikis Resistance in Cervical Cancer via Blocking UBE2C/ZEB1/2 Signal Axis.

ZEB1 ZEB2

1.75e-05460231679088
Pubmed

Novel roles for MLH3 deficiency and TLE6-like amplification in DNA mismatch repair-deficient gastrointestinal tumorigenesis and progression.

PMS2 MLH3

1.75e-05460218551179
Pubmed

miR-200b/c attenuates lipopolysaccharide-induced early pulmonary fibrosis by targeting ZEB1/2 via p38 MAPK and TGF-β/smad3 signaling pathways.

ZEB1 ZEB2

1.75e-05460229200203
Pubmed

The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2.

PMS2 MLH3

1.75e-05460211292842
Pubmed

miR-200 family and targets, ZEB1 and ZEB2, modulate uterine quiescence and contractility during pregnancy and labor.

ZEB1 ZEB2

1.75e-05460221079000
Pubmed

The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung.

ZEB1 ZEB2

1.75e-05460227215389
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

RIF1 PMS2 KIF23 PDE4D MTM1 PLEKHA6 PSRC1

2.53e-0550360716964243
Pubmed

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition.

ZEB1 ZEB2

2.92e-05560218829540
Pubmed

Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteins.

ZEB1 ZEB2

2.92e-05560212743039
Pubmed

Opposing functions of ZEB proteins in the regulation of the TGFbeta/BMP signaling pathway.

ZEB1 ZEB2

2.92e-05560212743038
Pubmed

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression.

ZEB1 ZEB2

2.92e-05560219651985
Pubmed

ZEB1, ZEB2, and the miR-200 family form a counterregulatory network to regulate CD8+ T cell fates.

ZEB1 ZEB2

2.92e-05560229449309
Pubmed

Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expression.

ZEB1 ZEB2

4.37e-05660212161443
Pubmed

miR-200c is aberrantly expressed in leiomyomas in an ethnic-dependent manner and targets ZEBs, VEGFA, TIMP2, and FBLN5.

ZEB1 ZEB2

4.37e-05660222685266
Pubmed

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.

PMS2 MLH3

4.37e-05660220603073
Pubmed

KIF14 and citron kinase act together to promote efficient cytokinesis.

KIF23 CIT

4.37e-05660216431929
Pubmed

Dissecting the role of Rho-mediated signaling in contractile ring formation.

KIF23 CIT

4.37e-05660216236794
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RIF1 KIF23 ZEB1 GZMB RIMS1 SCFD1 RERE ATP2A2

5.35e-0577460815302935
Pubmed

Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancer.

PMS2 MLH3

6.11e-05760219115210
Pubmed

Genetic investigation of DNA-repair pathway genes PMS2, MLH1, MSH2, MSH6, MUTYH, OGG1 and MTH1 in sporadic colon cancer.

PMS2 MUTYH

6.11e-05760217417778
Pubmed

Mismatch repair gene polymorphisms and survival in invasive ovarian cancer patients.

PMS2 MLH3

6.11e-05760218723338
Pubmed

Common variants in mismatch repair genes and risk of invasive ovarian cancer.

PMS2 MLH3

6.11e-05760216774946
Pubmed

Common variants in mismatch repair genes and risk of colorectal cancer.

PMS2 MLH3

6.11e-05760218364438
Pubmed

Pc2-mediated sumoylation of Smad-interacting protein 1 attenuates transcriptional repression of E-cadherin.

ZEB1 ZEB2

8.14e-05860216061479
Pubmed

FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.

PMS2 MLH3

8.14e-05860234469738
Pubmed

A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration.

ZEB1 ZEB2

8.14e-05860230271956
Pubmed

Interaction between Smad-interacting protein-1 and the corepressor C-terminal binding protein is dispensable for transcriptional repression of E-cadherin.

ZEB1 ZEB2

8.14e-05860212714599
Pubmed

Atypical ubiquitin E3 ligase complex Skp1-Pam-Fbxo45 controls the core epithelial-to-mesenchymal transition-inducing transcription factors.

ZEB1 ZEB2

8.14e-05860225460509
Pubmed

Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I.

PMS2 MLH3

8.14e-05860216260499
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZEB1 POLH RCOR3 RERE ZEB2 GPRASP2

8.42e-0541860634709266
Pubmed

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.

ZEB1 ZEB2

1.05e-04960224769727
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CEP350 PWWP2A PMS2 KIF23 NSD2 SMC6 KDM1B

1.20e-0464560725281560
Pubmed

Maternal diabetes induces senescence and neural tube defects sensitive to the senomorphic rapamycin.

ZEB1 ZEB2

1.31e-041060234193422
Pubmed

The functional interactome landscape of the human histone deacetylase family.

PWWP2A RIF1 PDCD11 RCOR3 RERE

1.44e-0428960523752268
Pubmed

A census of human transcription factors: function, expression and evolution.

MYT1L ZEB1 NSD2 RCOR3 HBP1 POU3F4 RERE ZEB2

1.61e-0490860819274049
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

MYT1L RIMS1

1.91e-041260227824329
Pubmed

Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission.

PMS2 PDE4D MTM1 GPRASP2

2.03e-0416760425659891
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP350 PWWP2A DGKD PLEKHA6 DDHD2 REXO1L1P

2.06e-0449360615368895
Pubmed

A High-Density Map for Navigating the Human Polycomb Complexome.

PWWP2A RCOR3 RERE KDM1B ATP2A2 DSN1

2.11e-0449560627705803
Pubmed

Identification of novel genetic Loci associated with thyroid peroxidase antibodies and clinical thyroid disease.

PTPN22 RERE

2.26e-041360224586183
Pubmed

Noncanonical role of transferrin receptor 1 is essential for intestinal homeostasis.

ZEB1 ZEB2

2.63e-041460226324903
InteractionTWIST1 interactions

RIF1 KIF23 NSD2 ATP2A2 ZEB2 PSRC1

8.38e-06170576int:TWIST1
GeneFamilyMutL homologs

PMS2 MLH3

3.46e-0544421027
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZEB1 ZEB2

5.96e-0415442529
GeneFamilyPWWP domain containing

PWWP2A NSD2

1.30e-03224421147
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_NK_CELL

RIF1 KIF23 NSD2 POLH SMC6 ATP2A2 DSN1 PSRC1 MUTYH

2.34e-05694599M45767
CoexpressionHE_LIM_SUN_FETAL_LUNG_C4_CYCLING_T_CELL

RIF1 KIF23 ZEB1 NSD2 POLH SMC6 CIT DSN1 PSRC1 MUTYH

4.24e-059395910M45768
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

CEP350 RIF1 ZEB1 NSD2 ATP2A2

5.36e-05180595M8239
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

CEP350 RIF1 KIF23 MLH3 MTM1 VPS13B

5.79e-05300596M8702
CoexpressionGSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_DN

PLEKHA6 CARNS1 ZEB2 GPRASP2 OPLAH

8.61e-05199595M3583
CoexpressionGSE24142_ADULT_VS_FETAL_DN3_THYMOCYTE_UP

MAP4K3 HBP1 PTPN22 DDHD2 ZEB2

8.82e-05200595M4584
CoexpressionGSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN

SMC6 HBP1 DGKD PTPN22 RERE

8.82e-05200595M9735
CoexpressionGSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP

MTM1 SMC6 HBP1 SCFD1 VPS13B

8.82e-05200595M5556
CoexpressionHE_LIM_SUN_FETAL_LUNG_C5_PRO_B_CELL

SOCS2 RIF1 KIF23 NSD2 CIT DSN1 PSRC1

9.66e-05478597M45785
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND4A PDE4D MAP4K3 CORIN RERE PLEKHA6 ZEB2 VPS13B

2.10e-10193608779276e775cb2492e8dd36436295a536084a6415
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A SMC6 DGKD RERE LRCH1 ZEB2

8.78e-081636066bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 PDE4D GZMB DGKD PTPN22 ZEB2

2.38e-07193606778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCellPND07-28-samps-Lymphocyte|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ACAP1 GZMB PTPN22 DSN1 MUTYH

2.27e-06157605105f2711d7bae3be36714954e103c61cf021f957
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 KIF23 GZMB CIT KLHL4

3.55e-06172605e495efd25aec60b97ac2b5aa861651bd73174a17
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A SMC6 DGKD RERE ZEB2

3.65e-06173605d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellASK452-Immune-B_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

GZMB SMC6 GPATCH2 MUTYH OPLAH

3.75e-0617460569723f5666abc3af5f0431901a60246c9915ef81
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 POLH CMTR2 PSRC1 KLHL4

4.31e-06179605df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCellIPF-Lymphoid-ILC_A|IPF / Disease state, Lineage and Cell class

ACAP1 DENND4A ZEB1 GZMB PTPN22

4.80e-0618360549bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 NSD2 GZMB MUTYH KLHL4

4.93e-06184605b998803180322a5ea2b567928dea531c26816c3c
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ZEB1 HIPK2 RIMS1 MMP2 ZEB2

5.20e-061866057def03dd856b765bd3f493288641981c4f7fd26e
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 PDE4D GZMB PTPN22 ZEB2

5.33e-06187605d17352f769c3c66601b65d060626eecff41b0482
ToppCell10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYT1L ZEB1 RIMS1 RERE PLEKHA6

5.47e-06188605e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIT DSN1 PSRC1 MUTYH

5.62e-06189605bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIT DSN1 PSRC1 MUTYH

5.62e-0618960596f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAP4K3 SMC6 DGKD RERE ZEB2

5.76e-06190605ed100e271aac82806f59e0c613ccda63f59100c1
ToppCellCOVID-19-kidney-NK|kidney / Disease (COVID-19 only), tissue and cell type

ACAP1 GZMB DGKD PTPN22 ZEB2

5.76e-06190605e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCellControl-Lymphoid-ILC_A|Control / Disease state, Lineage and Cell class

ACAP1 DENND4A ZEB1 GZMB PTPN22

5.91e-061916051ca73582dc3d28322b5ee841010067589d848acc
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEP350 RIF1 NSD2 HIPK2 LRCH1

6.06e-061926051ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-CD4_T|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACAP1 DENND4A ZEB1 PTPN22 PLEKHA6

6.22e-061936059c9434a3297b85774b4f0ecab6294f44d738e29f
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACAP1 PDE4D GZMB PTPN22 ZEB2

6.38e-0619460564535db0420e53e4d777d2333b5051e63e8a3373
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A SMC6 DGKD RERE ZEB2

6.54e-06195605481989d2e5bd2582da3d86b0155c4d6615317067
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DENND4A SMC6 DGKD RERE ZEB2

6.54e-061956056108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACAP1 GZMB PTPN22 ZEB2 KLHL4

7.22e-061996057d69785717073491b5fb81bf24db0175f86cd0b0
ToppCellsevere-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE4D GZMB PTPN22 ZEB2 KLHL4

7.39e-062006052253d74049cc49c92e897ff4aa298d913daeb739
ToppCellBronchial-NucSeq-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ACAP1 GZMB PTPN22 ZEB2 KLHL4

7.39e-06200605bfbd2ccf4b28901aad63d70a382a8247e4458ba6
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

1.77e-051156043ab39d28717ae585d84c0e0686508faab2fc2e3b
ToppCellLPS_only-Endothelial-Endothelial-FOXM1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 DCAF17 CIT KLHL4

3.22e-051346044d8f7ddad02fe76a614771e115ebb8e04623ba85
ToppCellLPS-IL1RA-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

3.22e-0513460492981dc68c1b3cdc53f9cf83386c47f0c6c98ae7
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 DENND4A GZMB PTPN22

5.69e-0515560493513bab53b40e9c3c91ab8e3316ea00a4f66cd2
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACAP1 SLC16A5 GZMB PTPN22

6.28e-051596048d958d79f5eb3ab683d1245ae7f4f22a2cefbc55
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP350 ACAP1 GZMB PTPN22

6.43e-05160604b2d8940ea8c068273b7da1589d3d6ae5110d8209
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP350 ACAP1 GZMB PTPN22

6.43e-051606049caab1bb63c7e66c44783852ee75b16bb40fa594
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP350 ACAP1 GZMB PTPN22

6.43e-05160604229841be7b984a00a301cd5d88c11226a90d8a88
ToppCellE16.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP350 ACAP1 GZMB PTPN22

6.43e-0516060499c9ae2041445539fada842e1af01368669bfca0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

PDE4D GZMB PTPN22 ZEB2

6.59e-05161604a480107b1c7773f2081afca2657e0b7fc88a5645
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A KIF23 BNIPL CARNS1

6.91e-05163604abec4389cd88252449f110fe95416d67424b403a
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 GZMB PTPN22 VPS13B

6.91e-05163604e6213900f56257fe38ac7852351bea0340294be0
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 GZMB PTPN22 VPS13B

6.91e-05163604ed7319185c1ec384444309bb8be95691a0c2091c
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE4D GZMB PTPN22 ZEB2

6.91e-0516360411cc18f36604d9a5f4e7fb8626a8f0fb141da5e1
ToppCell3'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACAP1 GZMB PTPN22 VPS13B

6.91e-05163604ef35d7ff09aa364734fea7fdaab6260c0a3fbf09
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CIT GPRASP2 PSRC1

7.08e-051646044307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 GZMB PTPN22 KLHL4

7.08e-05164604e9e5a1462d8ed60b2e5bf603c8c47eb85bce83d5
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 BNIPL GZMB PTPN22

7.08e-05164604731b9c7d6f6ecfb14d4a8705e0ddac9fb460d9a8
ToppCellLPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CIT GPRASP2 PSRC1

7.08e-051646041d84aa5b925f502ee9c5fa39714490f613a58028
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 GZMB PTPN22 KLHL4

7.42e-051666040b7503e27e26dcbf7f1b893c32ce0b21ce58bd4a
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEP350 ACAP1 GZMB PTPN22

7.42e-0516660426f3d5e5e30b63b09b89cda23c423d12d887631f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 NSD2 POLH PSRC1

7.95e-05169604b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCell368C-Lymphocytic-ILC|368C / Donor, Lineage, Cell class and subclass (all cells)

ACAP1 PDE4D POLH PTPN22

8.32e-051716043b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell368C-Lymphocytic-ILC-ILC-2|368C / Donor, Lineage, Cell class and subclass (all cells)

ACAP1 PDE4D POLH PTPN22

8.32e-05171604fd01076574dcc82bfd4a1538812500543b16794f
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF23 LRCH1 ZEB2 PSRC1

8.32e-05171604e3cab55f39879e2bd3e8bda91802181075839bc4
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF23 LRCH1 ZEB2 PSRC1

8.32e-0517160452fdc2a4ec36fb91583b1215362548ceb6740ae1
ToppCellfacs-Lung-nan-3m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 SLC16A5 GZMB PTPN22

8.51e-051726047af0713c40ea48f1e92c859c4fc4d8f0137c4415
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D|367C / Donor, Lineage, Cell class and subclass (all cells)

BNIPL GZMB PTPN22 CMTR2

8.51e-051726046379ae0aca9007c3a8a87e3330908fc90961ad3f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 CORIN PTPN22 RIMS1

8.51e-051726043ffe721f62c0d20c1d765ecb15ed4e1aa88099f7
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 CORIN PTPN22 RIMS1

8.51e-051726042bbe3f601a56577d200aa7ba7031f7c19b988cc1
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACAP1 KIF23 POLH GZMB

8.51e-05172604282017db72d0537ac82aecc69393ccde9590be60
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

8.70e-05173604fde1fabb8d13d05998ac3f21ecb1fde6a7a2f337
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MLH3 GZMB CARNS1 MUTYH

8.70e-05173604b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

8.70e-05173604dcde3252ff96448d3a61039a4948c74ad321a218
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MLH3 GZMB DCAF17 PTPN22

8.90e-051746046987fe7959afce347282f632abc16d800ccab7c4
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 RIMS1 CIT PSRC1

8.90e-051746047b2f35add804981c7d588a996bdbca6ec11a1ca5
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

8.90e-0517460461aa89b56ebda0eba1ba675d5f036992967f670f
ToppCellLPS-antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

9.10e-0517560498cb577df466700e72d1bbc6689205ccf2e7fcba
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE4D GZMB PTPN22

9.30e-05176604dff11730f26b4b7d26ee83b665d0284bc847cac0
ToppCellfacs-GAT-Fat-3m-Lymphocytic|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 DENND4A GZMB PTPN22

9.30e-051766042e3f25a338842384517656d05776a52cbfc62b52
ToppCellfacs-GAT-Fat-3m-Lymphocytic-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 DENND4A GZMB PTPN22

9.30e-051766040823088bc6b19c7ad784d83c2ccdfae80611afab
ToppCellfacs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIT DSN1 PSRC1

9.51e-051776048a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell(01)_Cycling_Basal_(homeostasis)|World / shred by cell type and Timepoint

KIF23 CIT DSN1 PSRC1

9.51e-0517760405c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCellfacs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIT DSN1 PSRC1

9.51e-05177604e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

9.72e-051786047905621f5b2aa55324c5592d1d2fef763a5fa41f
ToppCellLPS-IL1RA+antiTNF-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

9.72e-05178604f914092c20130207193f97c6044ae61a9a440a86
ToppCelldroplet-Liver-LIVER-30m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE4D GZMB PTPN22

9.72e-0517860400a5d8f47373be4792bf53914db63a1aedc2d77a
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

9.93e-05179604de3ddc1264e43727be50d69b81cc84a3c91812a2
ToppCellLPS_only-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

9.93e-05179604def981e97e3ff9019910c9af3861ca0d08eb0d0f
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A ZEB1 GZMB PTPN22

9.93e-05179604cb880ef40c203c8bd16c4f69a70cf59f97ebbffd
ToppCellASK452-Immune-B_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

GZMB SMC6 GPATCH2 OPLAH

9.93e-05179604c3cf49c069e66db16d2fce1de4c52a4c4fe7e832
ToppCellLPS-IL1RA-Lymphocytic_NKT|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

9.93e-051796045ccf0824611ded5c673d94dff3048aedac12f1a8
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 NSD2 CIT PSRC1

9.93e-0517960454191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A ZEB1 GZMB PTPN22

9.93e-05179604686b9f745d290ca686b42d9505e9792c78667e6e
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF23 NSD2 CIT PSRC1

9.93e-05179604e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|368C / Donor, Lineage, Cell class and subclass (all cells)

MAP4K3 GZMB PTPN22 DSN1

9.93e-0517960410c7d371937d9d93c12c8d3465430ef9e0c2ec81
ToppCelldroplet-Large_Intestine-COLON_-_"PROM_Tm"-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A ZEB1 GZMB PTPN22

9.93e-051796041eb004e1a17e1f1e4337e0581e547c0f5a965e68
ToppCellNS-moderate-d_0-4-Lymphoid-CTL|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ACAP1 ZEB1 GZMB PTPN22

1.04e-041816047fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CARNS1 DSN1 PSRC1

1.06e-04182604bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCellIIH-Treg-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

PWWP2A DCAF17 LRCH1 DSN1

1.06e-041826045c7d02da9ca2bca49db9832704b6894dfaa08a71
ToppCellIPF-Lymphoid-ILC_A|World / Disease state, Lineage and Cell class

ACAP1 ZEB1 GZMB PTPN22

1.06e-04182604f91bb45baaec76cb3bb26eedbcf0709b2492e93f
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

1.08e-0418360459e8d07556390828f7557ba3fd2f7d49851498b7
ToppCellControl-Lymphocytic_NKT-iNKT/MAIT-iNKT-MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACAP1 GZMB PTPN22 OPLAH

1.08e-041836042c5707ada3442eb7100a2a5f9438d5a2ac53a9e1
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 PDE4D GZMB PTPN22

1.10e-04184604f9365feed31e48f3382588bab077f99c5a3f5b04
ToppCellCV-Severe-3|CV / Virus stimulation, Condition and Cluster

SOCS2 BNIPL GZMB FAM157B

1.10e-041846041c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCellCTRL-Lymphoid|CTRL / Disease state, Lineage and Cell class

ACAP1 ZEB1 PDE4D GZMB

1.10e-0418460426fb2c4e6cb9950c27eb15428e7e74e5abb4397d
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 DENND4A GZMB PTPN22

1.10e-04184604290b8ef0bc4b7b99a2b35b96a756699d3f233b96
ToppCellfacs-SCAT-Fat-18m-Lymphocytic|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAP1 DENND4A GZMB PTPN22

1.10e-0418460443313b0b4e4d4b18dd67ac0c525d7aa4db493f71
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|368C / Donor, Lineage, Cell class and subclass (all cells)

MTM1 GZMB CARNS1 MUTYH

1.10e-04184604d48807f9da48bdd015a54c606d2e2a311f181396
ToppCellnucseq-Immune-Lymphocytic_T/NK-Lymphocytic_T/NK-Treg|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ACAP1 DENND4A ZEB1 PTPN22

1.13e-04185604a86a3a1a187a4d8d7762bc6d3dcb22c982178d22
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZEB1 PDE4D GZMB PTPN22

1.13e-04185604f1263899a2d41d182022dc4ca62cbae08a463c89
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 NSD2 POLH PSRC1

1.13e-0418560430e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SOCS2 MTM1 CARNS1 MUTYH

1.13e-041856047925519b855f76444a0b57382ce35d89457b0b14
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ZEB1 HIPK2 MMP2 ZEB2

1.13e-041856041ac6a32cc56d5d819649bdd99518e2ead0eead4c
DiseaseMalignant neoplasm of breast

RIF1 ACAP1 ZEB1 NSD2 POLH GZMB SMC6 MMP2 ZEB2 VPS13B

3.57e-0510745710C0006142
DiseaseLynch Syndrome

PMS2 MLH3

1.31e-049572C4552100
Diseaserheumatic heart disease (biomarker_via_orthology)

ZEB1 ZEB2

2.39e-0412572DOID:0050827 (biomarker_via_orthology)
DiseaseEndometrial Carcinoma

PMS2 MLH3 ZEB1

3.71e-0472573C0476089
Diseasetemporal arteritis (is_implicated_in)

PTPN22 MMP2

4.32e-0416572DOID:13375 (is_implicated_in)
DiseaseOral Submucous Fibrosis

ZEB1 MMP2

5.50e-0418572C0029172
DiseaseFetal Growth Retardation

NSD2 MMP2

6.81e-0420572C0015934
DiseaseAdenocarcinoma of large intestine

PMS2 MLH3 MUTYH

8.60e-0496573C1319315
DiseaseLynch syndrome (is_implicated_in)

PMS2 MLH3

9.85e-0424572DOID:3883 (is_implicated_in)
DiseaseVitiligo

GZMB PTPN22 RERE

9.96e-04101573EFO_0004208
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

PMS2 MLH3

1.16e-0326572C0009405
DiseaseHereditary non-polyposis colorectal cancer syndrome

PMS2 MLH3

1.25e-0327572C1112155
DiseaseHereditary Nonpolyposis Colorectal Cancer

PMS2 MLH3

1.44e-0329572C1333990
Diseaseesophageal carcinoma

PDE4D ATP2A2

1.54e-0330572EFO_0002916
DiseaseBreast Cancer, Familial

PMS2 MUTYH

1.54e-0330572C0346153
Diseaseintracranial volume measurement

PDCD11 ATP2A2

1.86e-0333572EFO_0004886
Diseaseautoimmune thyroid disease

ACAP1 PTPN22 RERE

1.88e-03126573EFO_0006812

Protein segments in the cluster

PeptideGeneStartEntry
MGPTRKPNVCSRLSR

DCAF17

1

Q5H9S7
RNNGMPPRACTKVSS

GZMB

221

P10144
MSKCRKTPVQQLASP

CMTR2

1

Q8IYT2
PCSSPAAMRLAKQKS

CARNS1

491

A5YM72
AMAVKKPGPSCSRQE

ACAP1

491

Q15027
TSGPQMCSKRPARGR

DEDD

156

O75618
CRDKMNSPGLQTKEP

CIT

1426

O14578
QNTIETMRKPRCGNP

MMP2

91

P08253
QIPANRSKTAMSKCP

DENND4A

1566

Q7Z401
QRSKCRPPKGMYLTQ

RCOR3

211

Q9P2K3
RNMKKSICNSCPPNK

PTPN22

756

Q9Y2R2
QGTIKRCPMSGSPAK

MAP4K3

456

Q8IVH8
SKRVKENTPPRCAMV

HIPK2

831

Q9H2X6
TPSTLALCGQRPMRK

BNIPL

71

Q7Z465
SIICKPKNGPTSRQM

MLH3

276

Q9UHC1
LQDRAPSKRSPMCNQ

PDE4D

246

Q08499
NPSNPRPSKGKMMRC

NSD2

771

O96028
FSTRKNSMGIKRPAP

DDHD2

441

O94830
SPAVPKLSMAKCRRN

LRCH1

631

Q9Y2L9
KRPSNMKRESPTCNL

PSRC1

166

Q6PGN9
MQSPRTKPRKSTVGA

KLHL4

416

Q9C0H6
FCNRRQKEKRMTPPG

POU3F4

326

P49335
MAKPAACKTPRNAEN

RIMS1

61

Q86UR5
PGCRRPSSNKMLRSM

FAM157B

126

P0CG42
RKSMSVYCTPNKPSR

ATP2A2

491

P16615
PQIAKTYRCGMKPNT

KDM1B

161

Q8NB78
GKRSMQQLDPSPARK

DSN1

321

Q9H410
PGKTRNRSGMACKTT

REXO1L1P

246

Q8IX06
RKDSQSCRDKPQPMR

CEP350

2406

Q5VT06
TKQDCGRRPAARMNK

CORIN

786

Q9Y5Q5
VPKGRSQRKVSKSPC

DGKD

671

Q16760
VSATSPNKCKRPMNA

HBP1

426

O60381
SNKRTMTQPPEGCRD

GPATCH2

176

Q9NW75
REAMPNPKTSSSKRQ

KIF23

176

Q02241
KMAPKPQSRCTSTRS

PWWP2A

501

Q96N64
EMSKCKTSIRRGQPN

SYT14

466

Q8NB59
QTGNKRSKPLMRSEP

RIF1

1296

Q5UIP0
KAQTGPPRVDKMTQC

OPLAH

651

O14841
RPKTEAQAMSGARPK

GPRASP2

61

Q96D09
QMCKDKRTGPEAPRN

SOCS2

131

O14508
PNNMPGSTRIKARKR

SLCO6A1

336

Q86UG4
SSPCSRKKPRMGQQV

MUTYH

511

Q9UIF7
KRNKTPVQDCPRMRG

PRAMEF27

131

A3QJZ7
GKRNPKSPLACTNKR

POLH

681

Q9Y253
MSTLRSGRKKQPASP

RERE

581

Q9P2R6
MSKCKISIRRGRPNP

SYT14P1

101

Q58G82
GPAAKRTMRPTQKDS

PDCD11

996

Q14690
PRTNPDKIAQRKSSM

PLEKHA6

301

Q9Y2H5
PGKQRSPEIMCQSSR

SLC16A5

446

O15375
RCSQPLVGMSGKRNK

MTM1

241

Q13496
PKMLRGNDSSVPRNK

SCFD1

571

Q8WVM8
RAVMQSQKPPKNCRE

SMC6

621

Q96SB8
SDSPGVMCRPSRVKQ

PMS2

791

P54278
RRTSVKQKPMGSPVS

PRSS55

311

Q6UWB4
MADGPRCKRRKQANP

ZEB1

1

P37275
PPKLMLKFNRQCGST

VN1R5

341

Q7Z5H4
TKSSIKPRRMQQAAP

VPS13B

116

Q7Z7G8
MADGPRCKRRKQANP

ZEB2

6

O60315
IQCTPQKAKPMRAAA

TUT7

1411

Q5VYS8
TRCREMPQNLSTKPQ

MYT1L

741

Q9UL68