Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine kinase activity	CDK8 SMG1 STK36 CAMK1D RPS6KA3 CDK19 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 MAP4K1 UHMK1 TAOK1 MAP4K2 NLK CDK2 CDK3 DYRK3	3.24e-11	363	168	20	GO:0106310
GeneOntologyMolecularFunction	protein kinase activity	CDK8 EPHB4 SMG1 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	4.09e-11	600	168	25	GO:0004672
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK8 EPHB4 SMG1 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 DGKD PFKP NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	4.81e-11	709	168	27	GO:0016773
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK8 SMG1 STK36 CAMK1D RPS6KA3 CDK19 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 MAP4K1 UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	1.87e-10	446	168	21	GO:0004674
GeneOntologyMolecularFunction	kinase activity	CDK8 EPHB4 SMG1 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 DGKD PFKP NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	2.55e-10	764	168	27	GO:0016301
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	CDK8 EPHB4 MED20 SMG1 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 DGKD PFKP NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	4.97e-09	938	168	28	GO:0016772
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDK8 CDK19 CDKL4 CDKL1 CDK2 CDK3	1.63e-07	30	168	6	GO:0004693
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDK8 CDK19 CDKL4 CDKL1 CDK2 CDK3	1.63e-07	30	168	6	GO:0097472
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNHD1 DNAH3 DNAH17 DYNC1H1	1.35e-05	18	168	4	GO:0008569
GeneOntologyMolecularFunction	tau-protein kinase activity	GSK3A GSK3B TAOK2 TAOK1	3.14e-05	22	168	4	GO:0050321
GeneOntologyMolecularFunction	estrogen binding	PDE3A ESR2	7.04e-05	2	168	2	GO:0099130
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNG3 KCNC4 KCNG1 KCNS3	8.45e-05	28	168	4	GO:0005251
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNHD1 DNAH3 DNAH17 DYNC1H1	8.45e-05	28	168	4	GO:0051959
GeneOntologyMolecularFunction	gated channel activity	HTR1B GRID2 KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 SCNN1B SCNN1D KCNS3 NALF2	1.27e-04	334	168	11	GO:0022836
GeneOntologyMolecularFunction	voltage-gated potassium channel activity	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	2.24e-04	102	168	6	GO:0005249
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNHD1 DNAH3 DNAH17 DYNC1H1	2.57e-04	37	168	4	GO:0045505
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	ERCC6L CHD3 CHD4 CHD5	2.57e-04	37	168	4	GO:0140658
GeneOntologyMolecularFunction	voltage-gated monoatomic cation channel activity	HTR1B KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	3.06e-04	152	168	7	GO:0022843
GeneOntologyMolecularFunction	nuclear estrogen receptor activity	PDE3A ESR2	4.18e-04	4	168	2	GO:0030284
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	HTR1B KCNG3 SLC13A2 KCNV1 KCNC4 KCNF1 KCNG1 SCNN1B SCNN1D KCNS3 NALF2 SLC4A9	5.89e-04	465	168	12	GO:0046873
GeneOntologyMolecularFunction	tau protein binding	GSK3A GSK3B TAOK2 TAOK1	5.99e-04	46	168	4	GO:0048156
GeneOntologyMolecularFunction	monoatomic cation channel activity	HTR1B KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 SCNN1B SCNN1D KCNS3 NALF2	6.72e-04	343	168	10	GO:0005261
GeneOntologyMolecularFunction	potassium channel activity	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	7.55e-04	128	168	6	GO:0005267
GeneOntologyMolecularFunction	G protein-coupled serotonin receptor activity	HTR1B HTR1D CHRM4	8.01e-04	22	168	3	GO:0004993
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity	HTR1B KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	8.97e-04	182	168	7	GO:0005244
GeneOntologyMolecularFunction	voltage-gated channel activity	HTR1B KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	9.57e-04	184	168	7	GO:0022832
GeneOntologyMolecularFunction	MAP kinase kinase kinase kinase activity	MAP4K1 MAP4K2	1.03e-03	6	168	2	GO:0008349
GeneOntologyMolecularFunction	ATP hydrolysis activity	DNAH3 ERCC6L ABCA12 ABCB5 SRPRA CHD3 CHD4 MDN1 CHD5 ASCC3 DYNC1H1	1.31e-03	441	168	11	GO:0016887
GeneOntologyMolecularFunction	monoatomic ion channel activity	HTR1B GRID2 KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 SCNN1B SCNN1D KCNS3 NALF2	1.79e-03	459	168	11	GO:0005216
GeneOntologyMolecularFunction	aspartic endopeptidase activity, intramembrane cleaving	SPPL2A SPPL2C	1.91e-03	8	168	2	GO:0042500
GeneOntologyMolecularFunction	ATP-dependent activity	DNHD1 DNAH3 ERCC6L ABCA12 ABCB5 SRPRA CHD3 CHD4 MDN1 CHD5 DNAH17 ASCC3 DYNC1H1	2.12e-03	614	168	13	GO:0140657
GeneOntologyMolecularFunction	microtubule motor activity	DNHD1 DNAH3 DNAH17 DYNC1H1	2.88e-03	70	168	4	GO:0003777
GeneOntologyMolecularFunction	potassium ion transmembrane transporter activity	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	2.93e-03	167	168	6	GO:0015079
GeneOntologyCellularComponent	voltage-gated potassium channel complex	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.06e-04	91	172	6	GO:0008076
GeneOntologyCellularComponent	potassium channel complex	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	2.22e-04	104	172	6	GO:0034705
GeneOntologyCellularComponent	CHD-type complex	CHD3 CHD4 CHD5	3.42e-04	17	172	3	GO:0090545
GeneOntologyCellularComponent	NuRD complex	CHD3 CHD4 CHD5	3.42e-04	17	172	3	GO:0016581
GeneOntologyCellularComponent	calpain complex	CAPN1 CAPN2	4.00e-04	4	172	2	GO:0110158
GeneOntologyCellularComponent	CKM complex	CDK8 CDK19	6.62e-04	5	172	2	GO:1990508
GeneOntologyCellularComponent	cation channel complex	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 SCNN1B SCNN1D KCNS3	7.52e-04	235	172	8	GO:0034703
GeneOntologyCellularComponent	dynein complex	DNHD1 DNAH3 DNAH17 DYNC1H1	1.02e-03	54	172	4	GO:0030286
GeneOntologyCellularComponent	axonemal dynein complex	DNHD1 DNAH3 DNAH17	1.10e-03	25	172	3	GO:0005858
Domain	Prot_kinase_dom	CDK8 EPHB4 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	1.06e-11	489	166	24	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK8 EPHB4 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	1.26e-11	493	166	24	PS50011
Domain	Kinase-like_dom	CDK8 EPHB4 SMG1 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	1.45e-11	542	166	25	IPR011009
Domain	PROTEIN_KINASE_ATP	CDK8 EPHB4 STK36 CAMK1D RPS6KA3 CDK19 STYK1 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	1.96e-11	459	166	23	PS00107
Domain	Pkinase	CDK8 STK36 CAMK1D RPS6KA3 CDK19 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 MAP4K1 TBCK UHMK1 TAOK1 STKLD1 MAP4K2 NLK CDK2 CDK3 DYRK3	2.70e-11	381	166	21	PF00069
Domain	Ser/Thr_kinase_AS	CDK8 STK36 CAMK1D RPS6KA3 CDK19 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 MAP4K1 UHMK1 TAOK1 MAP4K2 NLK CDK2 CDK3 DYRK3	4.59e-10	357	166	19	IPR008271
Domain	S_TKc	CDK8 STK36 CAMK1D RPS6KA3 CDK19 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 MAP4K1 UHMK1 TAOK1 MAP4K2 NLK CDK2 CDK3 DYRK3	5.04e-10	359	166	19	SM00220
Domain	PROTEIN_KINASE_ST	CDK8 STK36 CAMK1D RPS6KA3 CDK19 CDKL4 NEK9 CDKL1 GSK3A GSK3B TAOK2 MAP4K1 UHMK1 TAOK1 MAP4K2 NLK CDK2 CDK3 DYRK3	5.79e-10	362	166	19	PS00108
Domain	Protein_kinase_ATP_BS	CDK8 EPHB4 STK36 CAMK1D RPS6KA3 CDK19 CDKL1 GSK3A GSK3B TAOK2 TIE1 MAP4K1 TAOK1 MAP4K2 NLK CDK2 CDK3 DYRK3	8.12e-09	379	166	18	IPR017441
Domain	K_chnl_volt-dep_Kv	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.14e-07	27	166	6	IPR003968
Domain	VG_K_chnl	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	4.09e-07	33	166	6	IPR028325
Domain	CHD_N	CHD3 CHD4 CHD5	6.90e-07	3	166	3	IPR012958
Domain	CHD_C2	CHD3 CHD4 CHD5	6.90e-07	3	166	3	IPR012957
Domain	CHDCT2	CHD3 CHD4 CHD5	6.90e-07	3	166	3	PF08074
Domain	CHDNT	CHD3 CHD4 CHD5	6.90e-07	3	166	3	PF08073
Domain	DUF1086	CHD3 CHD4 CHD5	6.90e-07	3	166	3	IPR009462
Domain	DUF1087	CHD3 CHD4 CHD5	6.90e-07	3	166	3	IPR009463
Domain	DUF1087	CHD3 CHD4 CHD5	6.90e-07	3	166	3	PF06465
Domain	DUF1086	CHD3 CHD4 CHD5	6.90e-07	3	166	3	PF06461
Domain	DUF1087	CHD3 CHD4 CHD5	6.90e-07	3	166	3	SM01147
Domain	DUF1086	CHD3 CHD4 CHD5	6.90e-07	3	166	3	SM01146
Domain	BTB_2	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	7.32e-06	53	166	6	PF02214
Domain	T1-type_BTB	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	7.32e-06	53	166	6	IPR003131
Domain	Channel_four-helix_dom	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.12e-05	57	166	6	IPR027359
Domain	-	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.12e-05	57	166	6	1.20.120.350
Domain	K_chnl_volt-dep_Kv9	KCNG3 KCNF1 KCNS3	2.35e-05	7	166	3	IPR003971
Domain	SNF2_N	ERCC6L CHD3 CHD4 CHD5	1.78e-04	32	166	4	IPR000330
Domain	SNF2_N	ERCC6L CHD3 CHD4 CHD5	1.78e-04	32	166	4	PF00176
Domain	Dynein_HC_stalk	DNHD1 DNAH3 DYNC1H1	2.34e-04	14	166	3	IPR024743
Domain	Dynein_heavy_dom-2	DNHD1 DNAH3 DYNC1H1	2.34e-04	14	166	3	IPR013602
Domain	DHC_N2	DNHD1 DNAH3 DYNC1H1	2.34e-04	14	166	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH3 MDN1 DYNC1H1	2.34e-04	14	166	3	IPR011704
Domain	MT	DNHD1 DNAH3 DYNC1H1	2.34e-04	14	166	3	PF12777
Domain	AAA_5	DNAH3 MDN1 DYNC1H1	2.34e-04	14	166	3	PF07728
Domain	DHC_fam	DNHD1 DNAH3 DYNC1H1	2.90e-04	15	166	3	IPR026983
Domain	Dynein_heavy	DNHD1 DNAH3 DYNC1H1	2.90e-04	15	166	3	PF03028
Domain	Dynein_heavy_dom	DNHD1 DNAH3 DYNC1H1	2.90e-04	15	166	3	IPR004273
Domain	AAA	DNAH3 ABCA12 ABCB5 SRPRA MDN1 ASCC3 DYNC1H1	3.06e-04	144	166	7	SM00382
Domain	AAA+_ATPase	DNAH3 ABCA12 ABCB5 SRPRA MDN1 ASCC3 DYNC1H1	3.06e-04	144	166	7	IPR003593
Domain	WD40_repeat_dom	AAMP NWD1 DPH7 WDR18 ARHGEF17 WDR93 SCAP WDR11 RPTOR CFAP57	3.33e-04	297	166	10	IPR017986
Domain	MAPKKKK	MAP4K1 MAP4K2	4.66e-04	4	166	2	IPR021160
Domain	Ion_trans_dom	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	5.44e-04	114	166	6	IPR005821
Domain	Ion_trans	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	5.44e-04	114	166	6	PF00520
Domain	PA	ZNRF4 SPPL2A SPPL2C	6.02e-04	19	166	3	PF02225
Domain	PA_domain	ZNRF4 SPPL2A SPPL2C	6.02e-04	19	166	3	IPR003137
Domain	ARM-like	KPNA5 SMG1 STK36 HUWE1 RPTOR UTP20 STKLD1 BRAT1 KPNA1	7.10e-04	270	166	9	IPR011989
Domain	TMEM132D_N	TMEM132C TMEM132D	7.72e-04	5	166	2	PF15705
Domain	TMEM132D_C	TMEM132C TMEM132D	7.72e-04	5	166	2	PF15706
Domain	Peptidase_A22B_SPP	SPPL2A SPPL2C	7.72e-04	5	166	2	IPR007369
Domain	TMEM132_M	TMEM132C TMEM132D	7.72e-04	5	166	2	IPR031437
Domain	TMEM132_C	TMEM132C TMEM132D	7.72e-04	5	166	2	IPR031436
Domain	TMEM132_N	TMEM132C TMEM132D	7.72e-04	5	166	2	IPR031435
Domain	TMEM132	TMEM132C TMEM132D	7.72e-04	5	166	2	IPR026307
Domain	TMEM132	TMEM132C TMEM132D	7.72e-04	5	166	2	PF16070
Domain	Peptidase_A22B	SPPL2A SPPL2C	7.72e-04	5	166	2	PF04258
Domain	-	AAMP NWD1 DPH7 WDR18 ARHGEF17 WDR93 SCAP WDR11 RPTOR CFAP57	8.11e-04	333	166	10	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	AAMP NWD1 DPH7 WDR18 ARHGEF17 WDR93 SCAP WDR11 RPTOR CFAP57	8.49e-04	335	166	10	IPR015943
Domain	HEAT	STK36 RPTOR UTP20 BRAT1	8.64e-04	48	166	4	PF02985
Domain	WD_REPEATS_1	AAMP NWD1 DPH7 WDR18 WDR93 SCAP WDR11 RPTOR CFAP57	8.73e-04	278	166	9	PS00678
Domain	WD_REPEATS_2	AAMP NWD1 DPH7 WDR18 WDR93 SCAP WDR11 RPTOR CFAP57	8.95e-04	279	166	9	PS50082
Domain	WD_REPEATS_REGION	AAMP NWD1 DPH7 WDR18 WDR93 SCAP WDR11 RPTOR CFAP57	8.95e-04	279	166	9	PS50294
Domain	ARM-type_fold	KPNA5 SMG1 STK36 GBF1 HUWE1 RPTOR UTP20 STKLD1 BRAT1 KPNA1	9.29e-04	339	166	10	IPR016024
Domain	BTB	ANKFY1 KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.15e-03	180	166	7	SM00225
Domain	Chromo_domain	CHD3 CHD4 CHD5	1.22e-03	24	166	3	IPR023780
Domain	BTB/POZ_dom	ANKFY1 KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.35e-03	185	166	7	IPR000210
Domain	SKP1/BTB/POZ	ANKFY1 KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.53e-03	189	166	7	IPR011333
Domain	Chromo	CHD3 CHD4 CHD5	1.54e-03	26	166	3	PF00385
Domain	ENaC	SCNN1B SCNN1D	1.60e-03	7	166	2	IPR004724
Domain	Arm_3	KPNA5 KPNA1	1.60e-03	7	166	2	PF16186
Domain	PSN	SPPL2A SPPL2C	1.60e-03	7	166	2	SM00730
Domain	Importing_su_alpha	KPNA5 KPNA1	1.60e-03	7	166	2	IPR024931
Domain	IBB	KPNA5 KPNA1	1.60e-03	7	166	2	PF01749
Domain	Arm_3	KPNA5 KPNA1	1.60e-03	7	166	2	IPR032413
Domain	Preselin/SPP	SPPL2A SPPL2C	1.60e-03	7	166	2	IPR006639
Domain	HEAT	STK36 RPTOR UTP20 BRAT1	1.76e-03	58	166	4	IPR000357
Domain	CHROMO_1	CHD3 CHD4 CHD5	1.92e-03	28	166	3	PS00598
Domain	CHROMO_2	CHD3 CHD4 CHD5	1.92e-03	28	166	3	PS50013
Domain	-	NADSYN1 NIT1	2.12e-03	8	166	2	3.60.110.10
Domain	IBB	KPNA5 KPNA1	2.12e-03	8	166	2	PS51214
Domain	C-N_Hydrolase	NADSYN1 NIT1	2.12e-03	8	166	2	IPR003010
Domain	CN_hydrolase	NADSYN1 NIT1	2.12e-03	8	166	2	PF00795
Domain	CN_HYDROLASE	NADSYN1 NIT1	2.12e-03	8	166	2	PS50263
Domain	Na+channel_ASC_CS	SCNN1B SCNN1D	2.12e-03	8	166	2	IPR020903
Domain	WD40	AAMP NWD1 DPH7 WDR18 SCAP WDR11 RPTOR CFAP57	2.25e-03	259	166	8	PF00400
Domain	HMG_box_dom	CHD3 CHD4 KMT2C CHD5	2.67e-03	65	166	4	IPR009071
Domain	Helicase_C	ERCC6L CHD3 CHD4 CHD5 ASCC3	2.68e-03	107	166	5	PF00271
Domain	HELICc	ERCC6L CHD3 CHD4 CHD5 ASCC3	2.68e-03	107	166	5	SM00490
Domain	ASC	SCNN1B SCNN1D	2.71e-03	9	166	2	PF00858
Domain	ASC	SCNN1B SCNN1D	2.71e-03	9	166	2	PS01206
Domain	Na+channel_ASC	SCNN1B SCNN1D	2.71e-03	9	166	2	IPR001873
Domain	Importin-a_IBB	KPNA5 KPNA1	2.71e-03	9	166	2	IPR002652
Domain	5HT_rcpt	HTR1B HTR1D	2.71e-03	9	166	2	IPR002231
Domain	WD40	AAMP NWD1 DPH7 WDR18 SCAP WDR11 RPTOR CFAP57	2.78e-03	268	166	8	SM00320
Domain	Helicase_C	ERCC6L CHD3 CHD4 CHD5 ASCC3	2.79e-03	108	166	5	IPR001650
Domain	Chromodomain-like	CHD3 CHD4 CHD5	2.83e-03	32	166	3	IPR016197
Domain	HELICASE_CTER	ERCC6L CHD3 CHD4 CHD5 ASCC3	2.90e-03	109	166	5	PS51194
Domain	HELICASE_ATP_BIND_1	ERCC6L CHD3 CHD4 CHD5 ASCC3	2.90e-03	109	166	5	PS51192
Domain	DEXDc	ERCC6L CHD3 CHD4 CHD5 ASCC3	2.90e-03	109	166	5	SM00487
Domain	Helicase_ATP-bd	ERCC6L CHD3 CHD4 CHD5 ASCC3	3.02e-03	110	166	5	IPR014001
Domain	WD40_repeat	AAMP NWD1 DPH7 WDR18 SCAP WDR11 RPTOR CFAP57	3.05e-03	272	166	8	IPR001680
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.73e-06	41	128	6	MM14546
Pathway	REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	2.31e-06	43	128	6	M1056
Pubmed	Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.	RPS6KA3 NEK9 GSK3A GSK3B MAP4K1 MAP4K2 CDK2 CDK3	5.31e-09	78	172	8	17192257
Pubmed	The protein interaction landscape of the human CMGC kinase group.	CDK8 MED20 ICE2 RPS6KA3 CDK19 WDR18 SDR42E1 HUWE1 MED13L PFKP CDKL1 GSK3A GSK3B NLK CDK2 CDK3 DYRK3 KPNA1	1.28e-08	695	172	18	23602568
Pubmed	International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels.	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	4.48e-08	40	172	6	16382104
Pubmed	Mediator cyclin-dependent kinases upregulate transcription of inflammatory genes in cooperation with NF-κB and C/EBPβ on stimulation of Toll-like receptor 9.	CDK8 CDK19 TLR9	1.19e-07	3	172	3	28151579
Pubmed	N-terminal cleavage of GSK-3 by calpain: a new form of GSK-3 regulation.	CAPN1 GSK3A GSK3B	1.19e-07	3	172	3	17569662
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EPHB4 TBC1D9B ERCC6L CAPN2 SRPRA HUWE1 PFKP GSK3A GSK3B TAOK2 JAG2 SCAP RPTOR TVP23C UTP20 ASCC3 BRAT1 DYNC1H1 CDK2	2.48e-07	942	172	19	31073040
Pubmed	17-Beta-estradiol increases neuronal excitability through MAP kinase-induced calpain activation.	ESR2 CAPN1 CAPN2	4.74e-07	4	172	3	19995977
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPHB4 STK36 TBC1D9B GBF1 CTC1 HUWE1 MED13L CHRM4 SLC52A3 TAOK2 JAG2 KMT2C NADSYN1 SCAP MDN1 KCNG1 RPTOR CHD5 BRAT1 DYNC1H1	6.45e-07	1105	172	20	35748872
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	EPHB4 CAMK1D RPS6KA3 CAPN1 CAPN2 KCNG3 PLA2G4E GSK3A GSK3B KCNV1 KCNC4 KCNG1 MAP4K1 DNAH17 CDK2 CDK3	7.94e-07	730	172	16	34857952
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	DNAH3 TBC1D2 SRPRA HUWE1 MAGEB6 PFKP CSMD2 ARHGEF17 KMT2C RNF123 MDN1 KCNG1 UGCG UTP20 CFAP57 DYNC1H1	8.83e-07	736	172	16	29676528
Pubmed	Molecular analysis of spontaneous somatic mutants.	IGHV3-48 IGHV3-13 IGHV3-7	1.18e-06	5	172	3	401950
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	GBF1 ERCC6L TBC1D2 CHD3 CHD4 POGZ HUWE1 PFKP GSK3A GSK3B MDN1 MAP4K1 RPTOR UTP20 TAOK1 CDK2	1.69e-06	774	172	16	15302935
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	NR2C2 RPS6KA3 STYK1 NEK9 GSK3A TIE1 KCNG1 MAP4K1 KCNS3 MAP4K2 CDK3	2.75e-06	372	172	11	22939624
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	CAPN1 CAPN2 GSK3B	4.10e-06	7	172	3	20962236
Pubmed	mTORC1 is necessary but mTORC2 and GSK3β are inhibitory for AKT3-induced axon regeneration in the central nervous system.	GSK3A GSK3B RPTOR	4.10e-06	7	172	3	27026523
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	TREX1 NR2C2 ZDHHC18 GBF1 ANXA4 SRPRA VPS16 HUWE1 PFKP NEK9 GSK3A GGH SCAP MDN1 CD38 UGCG TVP23C ADGRE5	5.92e-06	1061	172	18	33845483
Pubmed	Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.	PSMD10 VPS16 HUWE1 RPTOR DYNC1H1	8.69e-06	56	172	5	27103069
Pubmed	Association of cyclin-dependent kinase 5 and its activator p35 with apoptotic cell death.	CDK8 CDK2 CDK3	9.77e-06	9	172	3	9438340
Pubmed	Proteolysis of the exodomain of recombinant protease-activated receptors: prediction of receptor activation or inactivation by MALDI mass spectrometry.	CAPN1 CAPN2 F2R	9.77e-06	9	172	3	10978167
Pubmed	DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA.	TLR9 GSK3A GSK3B	9.77e-06	9	172	3	15678105
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	SMG1 ANKFY1 GBF1 CDK19 MED13L KMT2C SCAP CHD5	1.76e-05	225	172	8	12168954
Pubmed	The AAA-ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle.	CAPN1 CAPN2 HUWE1 RNF123	1.86e-05	32	172	4	36278411
Pubmed	Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia.	HTR1B HTR1D GSK3B	1.90e-05	11	172	3	18855532
Pubmed	Decreased store operated Ca2+ entry in dendritic cells isolated from mice expressing PKB/SGK-resistant GSK3.	GSK3A GSK3B	2.43e-05	2	172	2	24523925
Pubmed	Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.	CHD3 CHD4	2.43e-05	2	172	2	7560064
Pubmed	The phe-124-Cys and A-161T variants of the human 5-HT1B receptor gene are not major determinants of the clinical response to sumatriptan.	HTR1B HTR1D	2.43e-05	2	172	2	17501853
Pubmed	Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.	HTR1B HTR1D	2.43e-05	2	172	2	1557407
Pubmed	[Expression of calpain 1 and calpain 2 during the skin incised wound healing in mice].	CAPN1 CAPN2	2.43e-05	2	172	2	17619446
Pubmed	Differential roles of glycogen synthase kinase-3 isoforms in the regulation of transcriptional activation.	GSK3A GSK3B	2.43e-05	2	172	2	16912034
Pubmed	Calpain 1 and 2 are required for RNA replication of echovirus 1.	CAPN1 CAPN2	2.43e-05	2	172	2	18032503
Pubmed	Are genetic variations in OXTR, AVPR1A, and CD38 genes important to social integration? Results from two large U.S. cohorts.	OXTR CD38	2.43e-05	2	172	2	24209975
Pubmed	Loss of glycogen synthase kinase 3 isoforms during murine oocyte growth induces offspring cardiac dysfunction.	GSK3A GSK3B	2.43e-05	2	172	2	25833158
Pubmed	Calpain-2 participates in the process of calpain-1 inactivation.	CAPN1 CAPN2	2.43e-05	2	172	2	33078830
Pubmed	Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation.	GSK3A GSK3B	2.43e-05	2	172	2	22065737
Pubmed	Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.	CDK8 CDK19	2.43e-05	2	172	2	35181333
Pubmed	Tissue-specific expression and regulation of GSK-3 in human skeletal muscle and adipose tissue.	GSK3A GSK3B	2.43e-05	2	172	2	16757548
Pubmed	Regulatory functions of the Mediator kinases CDK8 and CDK19.	CDK8 CDK19	2.43e-05	2	172	2	30585107
Pubmed	Unique and overlapping functions of GSK-3 isoforms in cell differentiation and proliferation and cardiovascular development.	GSK3A GSK3B	2.43e-05	2	172	2	19064989
Pubmed	Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.	HTR1B HTR1D	2.43e-05	2	172	2	25170871
Pubmed	Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.	HTR1B HTR1D	2.43e-05	2	172	2	1652050
Pubmed	The role of glycogen synthase kinase 3 in the early stages of Alzheimers' disease.	GSK3A GSK3B	2.43e-05	2	172	2	18955053
Pubmed	Cloning of m-calpain 80 kD subunit from the axonal degeneration-resistant WLD(S) mouse mutant.	CAPN1 CAPN2	2.43e-05	2	172	2	9669314
Pubmed	Association study of GSK3 gene polymorphisms with schizophrenia and clozapine response.	GSK3A GSK3B	2.43e-05	2	172	2	18500637
Pubmed	A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene.	CDK2 CDK3	2.43e-05	2	172	2	11172011
Pubmed	The retroviral cyclin of walleye dermal sarcoma virus binds cyclin-dependent kinases 3 and 8.	CDK8 CDK3	2.43e-05	2	172	2	21067790
Pubmed	Glycogen synthase kinase-3 (Gsk-3) plays a fundamental role in maintaining DNA methylation at imprinted loci in mouse embryonic stem cells.	GSK3A GSK3B	2.43e-05	2	172	2	25833708
Pubmed	Vitamin D₃ regulation of body fat, cytokines, and calpain gene expression.	CAPN1 CAPN2	2.43e-05	2	172	2	25520983
Pubmed	Regulation of persistent sodium currents by glycogen synthase kinase 3 encodes daily rhythms of neuronal excitability.	GSK3A GSK3B	2.43e-05	2	172	2	27841351
Pubmed	P-glycoprotein is implicated in the inhibition of ceramide-induced apoptosis in TF-1 acute myeloid leukemia cells by modulation of the glucosylceramide synthase pathway.	UGCG PGP	2.43e-05	2	172	2	15661399
Pubmed	HIV Transcription Is Independent of Mediator Kinases.	CDK8 CDK19	2.43e-05	2	172	2	31044597
Pubmed	Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone induces phosphorylation of mu- and m-calpain in association with increased secretion, cell migration, and invasion.	CAPN1 CAPN2	2.43e-05	2	172	2	15471877
Pubmed	m-Calpain is required for preimplantation embryonic development in mice.	CAPN1 CAPN2	2.43e-05	2	172	2	16433929
Pubmed	Role of PKB/SGK-dependent phosphorylation of GSK-3α/β in vascular calcification during cholecalciferol overload in mice.	GSK3A GSK3B	2.43e-05	2	172	2	30119888
Pubmed	Regulation of Th1 cells and experimental autoimmune encephalomyelitis by glycogen synthase kinase-3.	GSK3A GSK3B	2.43e-05	2	172	2	23606540
Pubmed	Circadian rhythmicity of active GSK3 isoforms modulates molecular clock gene rhythms in the suprachiasmatic nucleus.	GSK3A GSK3B	2.43e-05	2	172	2	25724980
Pubmed	Neural precursor cells are protected from apoptosis induced by trophic factor withdrawal or genotoxic stress by inhibitors of glycogen synthase kinase 3.	GSK3A GSK3B	2.43e-05	2	172	2	17548347
Pubmed	Distinct roles of glycogen synthase kinase (GSK)-3alpha and GSK-3beta in mediating cardiomyocyte differentiation in murine bone marrow-derived mesenchymal stem cells.	GSK3A GSK3B	2.43e-05	2	172	2	19858210
Pubmed	Cyclic AMP and glycogen synthase kinase 3 form a regulatory loop in spermatozoa.	GSK3A GSK3B	2.43e-05	2	172	2	29574946
Pubmed	Glycogen synthase kinase 3: more than a namesake.	GSK3A GSK3B	2.43e-05	2	172	2	19366350
Pubmed	Inhibition of glycogen synthase kinase-3 is necessary for the rapid antidepressant effect of ketamine in mice.	GSK3A GSK3B	2.43e-05	2	172	2	21502951
Pubmed	Deficiency in the inhibitory serine-phosphorylation of glycogen synthase kinase-3 increases sensitivity to mood disturbances.	GSK3A GSK3B	2.43e-05	2	172	2	20357757
Pubmed	The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.	CHD3 CHD4	2.43e-05	2	172	2	7575689
Pubmed	Differential regulation of STAT family members by glycogen synthase kinase-3.	GSK3A GSK3B	2.43e-05	2	172	2	18550525
Pubmed	Glycogen synthase kinase 3 in chronic rhinosinusitis: two faces of a single enzyme in one disease.	GSK3A GSK3B	2.43e-05	2	172	2	23352529
Pubmed	Delay discounting, genetic sensitivity, and leukocyte telomere length.	ESR2 OXTR	2.43e-05	2	172	2	26903639
Pubmed	Phosphorylations of Serines 21/9 in Glycogen Synthase Kinase 3α/β Are Not Required for Cell Lineage Commitment or WNT Signaling in the Normal Mouse Intestine.	GSK3A GSK3B	2.43e-05	2	172	2	27284979
Pubmed	Glycogen synthase kinase-3 regulates the phosphorylation of severe acute respiratory syndrome coronavirus nucleocapsid protein and viral replication.	GSK3A GSK3B	2.43e-05	2	172	2	19106108
Pubmed	Calpains are required for invasive and metastatic potentials of human HCC cells.	CAPN1 CAPN2	2.43e-05	2	172	2	23733271
Pubmed	Glycogen synthase kinase-3 regulates inflammatory tolerance in astrocytes.	GSK3A GSK3B	2.43e-05	2	172	2	20553816
Pubmed	Involvement of calpains in growth factor-mediated migration.	CAPN1 CAPN2	2.43e-05	2	172	2	16971167
Pubmed	Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory.	CAPN1 CAPN2	2.43e-05	2	172	2	29258546
Pubmed	Protection against TBI-Induced Neuronal Death with Post-Treatment with a Selective Calpain-2 Inhibitor in Mice.	CAPN1 CAPN2	2.43e-05	2	172	2	28594313
Pubmed	Glycogen synthase kinase 3 regulates acrosomal exocytosis in mouse spermatozoa via dynamin phosphorylation.	GSK3A GSK3B	2.43e-05	2	172	2	25808536
Pubmed	Boosting CNS axon regeneration by harnessing antagonistic effects of GSK3 activity.	GSK3A GSK3B	2.43e-05	2	172	2	28630333
Pubmed	Regulation of glycogen synthase kinase 3 in human platelets: a possible role in platelet function?	GSK3A GSK3B	2.43e-05	2	172	2	14550568
Pubmed	Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.	CDK8 CDK19	2.43e-05	2	172	2	32560467
Pubmed	GSK3 inhibitor-BIO regulates proliferation of immortalized pancreatic mesenchymal stem cells (iPMSCs).	GSK3A GSK3B	2.43e-05	2	172	2	22384031
Pubmed	Isolation and chromosomal mapping of human glycogen synthase kinase-3 alpha and -3 beta encoding genes.	GSK3A GSK3B	2.43e-05	2	172	2	9809441
Pubmed	Immunhistochemical analysis for expression of calpain 1, calpain 2 and calpastatin in ovarian cancer.	CAPN1 CAPN2	2.43e-05	2	172	2	22335024
Pubmed	Distinct roles of GSK-3alpha and GSK-3beta phosphorylation in the heart under pressure overload.	GSK3A GSK3B	2.43e-05	2	172	2	19106302
Pubmed	Glycogen synthase kinase 3 regulates photic signaling in the suprachiasmatic nucleus.	GSK3A GSK3B	2.43e-05	2	172	2	28244152
Pubmed	Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.	HTR1B HTR1D	2.43e-05	2	172	2	25268648
Pubmed	Analysis of hepatic gene transcription in mice expressing insulin-insensitive GSK3.	GSK3A GSK3B	2.43e-05	2	172	2	16176184
Pubmed	Disruption of circadian rhythmicity and suprachiasmatic action potential frequency in a mouse model with constitutive activation of glycogen synthase kinase 3.	GSK3A GSK3B	2.43e-05	2	172	2	22986169
Pubmed	Varicella-zoster virus requires a functional PI3K/Akt/GSK-3alpha/beta signaling cascade for efficient replication.	GSK3A GSK3B	2.43e-05	2	172	2	16934436
Pubmed	Myocardial stress remodelling after regional infarction is independent of glycogen synthase kinase-3 inactivation.	GSK3A GSK3B	2.43e-05	2	172	2	20696171
Pubmed	Calcium-dependent plasma membrane repair requires m- or mu-calpain, but not calpain-3, the proteasome, or caspases.	CAPN1 CAPN2	2.43e-05	2	172	2	19781581
Pubmed	Calpain-1 and calpain-2 play opposite roles in retinal ganglion cell degeneration induced by retinal ischemia/reperfusion injury.	CAPN1 CAPN2	2.43e-05	2	172	2	27185592
Pubmed	Distinct regulatory functions of calpain 1 and 2 during neural stem cell self-renewal and differentiation.	CAPN1 CAPN2	2.43e-05	2	172	2	22432027
Pubmed	Regulation of basal gastric acid secretion by the glycogen synthase kinase GSK3.	GSK3A GSK3B	2.43e-05	2	172	2	20552232
Pubmed	GSK-3 parameters in lymphocytes of schizophrenic patients.	GSK3A GSK3B	2.43e-05	2	172	2	12379450
Pubmed	Cerebral calpain in fatal falciparum malaria.	CAPN1 CAPN2	2.43e-05	2	172	2	17359359
Pubmed	Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma.	GSK3A GSK3B	2.43e-05	2	172	2	28619606
Pubmed	Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis.	GSK3A GSK3B	2.43e-05	2	172	2	31607568
Pubmed	Glycogen synthase kinase-3 overexpression replicates electroretinogram anomalies of offspring at high genetic risk for schizophrenia and bipolar disorder.	GSK3A GSK3B	2.43e-05	2	172	2	24138923
Pubmed	GSK3β, but not GSK3α, inhibits the neuronal differentiation of neural progenitor cells as a downstream target of mammalian target of rapamycin complex1.	GSK3A GSK3B	2.43e-05	2	172	2	24397546
Pubmed	Impairments in cognition and neural precursor cell proliferation in mice expressing constitutively active glycogen synthase kinase-3.	GSK3A GSK3B	2.43e-05	2	172	2	25788881
Pubmed	Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity.	HTR1B HTR1D	2.43e-05	2	172	2	1315531
Pubmed	Isoform-specific hyperactivation of calpain-2 occurs presymptomatically at the synapse in Alzheimer's disease mice and correlates with memory deficits in human subjects.	CAPN1 CAPN2	2.43e-05	2	172	2	30177812
Pubmed	PKB/SGK-dependent GSK3-phosphorylation in the regulation of LPS-induced Ca2+ increase in mouse dendritic cells.	GSK3A GSK3B	2.43e-05	2	172	2	23817039
Interaction	KCNG1 interactions	TLR9 ZNRF4 DCST1 RNF123 KCNG1	6.53e-07	21	166	5	int:KCNG1
Interaction	STAT2 interactions	EPHB4 ESR2 CAPN2 DCST1 GSK3A GSK3B KPNA1	4.72e-06	81	166	7	int:STAT2
Interaction	PPP1R15B interactions	PDE3A GBF1 PTCHD3 ABCB5 ZNRF4 DCST1 CHRM4	5.13e-06	82	166	7	int:PPP1R15B
Interaction	KCNB2 interactions	KCNG3 TAOK2 KCNV1 KCNF1 KCNG1 KCNS3	1.72e-05	66	166	6	int:KCNB2
Interaction	SGK3 interactions	RPS6KA3 CHD3 CHD4 GSK3A GSK3B DYNC1H1	2.23e-05	69	166	6	int:SGK3
Interaction	KCNG3 interactions	KCNG3 KCNV1 KCNF1	4.45e-05	9	166	3	int:KCNG3
Interaction	STON1 interactions	ESR2 GSK3A GSK3B	4.45e-05	9	166	3	int:STON1
Interaction	PDE3B interactions	PDE3A TLR9 ZNRF4 RNF123 SCAP KCNC4 KCNS3	4.71e-05	115	166	7	int:PDE3B
Interaction	BCCIP interactions	CDK8 NR2C2 ESR2 CAPN1 CAPN2 GSK3A GSK3B CDK2	4.83e-05	157	166	8	int:BCCIP
GeneFamily	Cyclin dependent kinases	CDK8 CDK19 CDKL4 CDKL1 CDK2 CDK3	1.27e-08	26	116	6	496
GeneFamily	Potassium voltage-gated channels	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 KCNS3	1.97e-07	40	116	6	274
GeneFamily	WD repeat domain containing	AAMP NWD1 DPH7 WDR18 WDR93 SCAP WDR11 RPTOR CFAP57	4.85e-05	262	116	9	362
GeneFamily	PHD finger proteins\|NuRD complex	CHD3 CHD4 CHD5	5.43e-05	12	116	3	1305
GeneFamily	Cyclins\|Mediator complex	CDK8 MED20 CDK19 MED13L	5.70e-05	33	116	4	1061
GeneFamily	Sodium channels epithelial	SCNN1B SCNN1D	2.43e-04	4	116	2	185
GeneFamily	Mitogen-activated protein kinase kinase kinase kinases	MAP4K1 MAP4K2	4.03e-04	5	116	2	655
GeneFamily	PHD finger proteins	CHD3 CHD4 KMT2C CHD5	2.69e-03	90	116	4	88
GeneFamily	5-hydroxytryptamine receptors, G protein-coupled	HTR1B HTR1D	3.04e-03	13	116	2	170
GeneFamily	C2 domain containing\|Calpains	CAPN1 CAPN2	4.06e-03	15	116	2	975
GeneFamily	Dyneins, axonemal	DNAH3 DNAH17	5.21e-03	17	116	2	536
GeneFamily	Armadillo repeat containing\|Importins	KPNA5 KPNA1	5.84e-03	18	116	2	596
Coexpression	GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP	AAMP TP53INP1 ICE2 PHYHD1 MDN1 CD37 UGCG TAOK1 MAP4K2	7.07e-06	199	172	9	M3677
Coexpression	GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN	TREX1 CAMK1D TP53INP1 ESR2 CDK19 CHD3 MED13L RNF123 CD38	7.37e-06	200	172	9	M309
Coexpression	SOBOLEV_PBMC_PANDEMRIX_AGE_18_64YO_RESPONDERS_VS_NONRESPONDERS_7DY_UP	IGHV3-48 GGH GLDC CD38	1.19e-05	22	172	4	M41032
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A CDK19 STYK1 TM6SF1 F2R JAG2 TIE1 GPRC5B	7.79e-07	190	172	8	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 TP53INP1 IGHV3-13 IGHV3-7 SRPRA GGH GLDC CD38	1.02e-06	197	172	8	1e63879633f20646e44873ae6b662f6faf4806fd
ToppCell	facs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L ACRBP TBC1D2 RNF123 DNAH17 MAP4K2 DYRK3	3.84e-06	166	172	7	a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCell	facs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMS22L ACRBP TBC1D2 RNF123 DNAH17 MAP4K2 DYRK3	3.84e-06	166	172	7	0f641302a6b71c4badaaf20f51162bfc2386b167
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK36 MMS22L ERCC6L CTC1 JAG2 GPRC5B FCHSD1	4.85e-06	172	172	7	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR3 PDE3A ESPNL DGKD GRID2 ARHGEF17 CHD5	5.44e-06	175	172	7	d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	GPR3 PDE3A ESPNL DGKD GRID2 ARHGEF17 CHD5	5.44e-06	175	172	7	454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCell	10x5'-Liver-Lymphocytic_B_plasma\|Liver / Manually curated celltypes from each tissue	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.10e-06	186	172	7	a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCell	Control-Endothelial-Endothelial-Artery\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A STYK1 TM6SF1 F2R JAG2 MCTP1 TIE1	8.10e-06	186	172	7	2d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	SMG1 HUWE1 MED13L EPG5 KMT2C TAOK1 DYNC1H1	8.69e-06	188	172	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.99e-06	189	172	7	73ee4cfb1057832f700be59b6917dedde3e89880
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.99e-06	189	172	7	a1bda6ed5c52a5d33d229018cb5982cae6305533
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.99e-06	189	172	7	31594cc59eb1c5b01407dfd72b1487ecca8bf5ec
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.99e-06	189	172	7	c296660061b46e3abae1e7cf29df20274e5a8add
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A CDK19 STYK1 F2R JAG2 MCTP1 TIE1	8.99e-06	189	172	7	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.99e-06	189	172	7	f2daf4889ef98bbefe3e44832618ac102a75b4d9
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 TP53INP1 IGHV3-7 GGH GLDC CD38 SCNN1B	8.99e-06	189	172	7	9de17ade3cc3e9cd1394338bd048fb1ce64ac50f
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A CDK19 STYK1 JAG2 MCTP1 TIE1 GPRC5B	9.63e-06	191	172	7	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TM6SF1 JAG2 MCTP1 TIE1 TMEM178A TM4SF18 GPRC5B	9.96e-06	192	172	7	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	COVID_non-vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 IGHV3-13 IGHV3-7 SRPRA GGH GLDC CD38	1.03e-05	193	172	7	7b4b0271e4fbece703876acb053ae236afb7cdba
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TM6SF1 JAG2 MCTP1 TIE1 TMEM178A TM4SF18 GPRC5B	1.10e-05	195	172	7	b0979c1b5e4576468b8fe4e9027650859e598b34
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgM_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 TP53INP1 IGHV3-13 IGHV3-7 SRPRA GLDC CD38	1.14e-05	196	172	7	026a06d8d2089806823e6f6453d3ede84ae93bc6
ToppCell	COVID_vent-Lymphocytic-Plasma_cell-IgA_Plasmablast\|COVID_vent / Disease condition, Lineage, Cell class and subclass	IGHV3-48 TP53INP1 IGHV3-7 SRPRA GGH GLDC CD38	1.18e-05	197	172	7	99fe44ef42c65d24fe64947fd5bf6d91b9a4b2c3
ToppCell	Control_saline-Endothelial-Endothelial-Artery\|Control_saline / Treatment groups by lineage, cell group, cell type	PDE3A CDK19 TM6SF1 JAG2 OXTR TIE1 GPRC5B	1.30e-05	200	172	7	65b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDE3A CDK19 STYK1 JAG2 OXTR TIE1 GPRC5B	1.30e-05	200	172	7	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CDKL4 KCNG3 KCNG1 NALF2 NLK DYRK3	1.98e-05	143	172	6	5fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CAPN1 CSMD2 KCNV1 KCNF1 KCNG1 KPNA1	2.32e-05	147	172	6	8f725ff8fb4ced5db2643e80669d3f7945b820ab
ToppCell	Nasal_Brush-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	ZDHHC18 DPH7 DGKD MAP4K1 STRC FCHSD1	2.59e-05	150	172	6	d39d73a1de6a873292d48e469d9403f513045be3
ToppCell	10x5'-blood-Lymphocytic_B_plasma\|blood / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-13 IGHV3-7 GGH CD38 SCNN1B	2.59e-05	150	172	6	6bab0a8bf78ed7de9e1b67ede7496488f80f4863
ToppCell	Nasal_Brush-Epithelial-Club\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	ZDHHC18 DPH7 DGKD MAP4K1 STRC FCHSD1	2.59e-05	150	172	6	c68645ffcffe524cf1d9736cf72a15b37ed8dc3d
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	CDKL4 KCNF1 KCNG1 NALF2 NLK DYRK3	3.86e-05	161	172	6	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	3'_v3-blood-Lymphocytic_B_plasma-Plasma_cells\|blood / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-7 GGH GLDC CD38 SCNN1B	4.43e-05	165	172	6	1c0c24fe252b761cf879b83562e23c02f0b6489f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCB5 POPDC2 ARHGEF17 F2R UGCG	4.73e-05	167	172	6	b4ef07117d14da3d5fbced949e4dfcb01c392295
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCB5 POPDC2 ARHGEF17 F2R UGCG	4.73e-05	167	172	6	94fc7df7ca55cd722a8dbd153201a29891217473
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE3A ABCB5 POPDC2 ARHGEF17 F2R UGCG	4.73e-05	167	172	6	eff3723fe60755272eca237459165e436e919ece
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF473 DCST1 SEZ6L2 SLC52A3 TIE1 TMEM178A	5.23e-05	170	172	6	50c6c571591aa4b218caefe5778c570c809f567e
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF473 DCST1 SEZ6L2 SLC52A3 TIE1 TMEM178A	5.23e-05	170	172	6	8fe32dcf924d5f6665f7febbc9647d96b1e96f06
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF473 DCST1 SEZ6L2 SLC52A3 TIE1 TMEM178A	5.23e-05	170	172	6	3232db50b1a40f861e981a1b9c9073b81af9f832
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK8 PDE3A CAPN2 GGH TMEM270 NIT1	5.23e-05	170	172	6	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Deuterosomal\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PRSS54 DNAH3 TTC16 ANKUB1 DNAH17 CFAP57	5.58e-05	172	172	6	08ad76412c9cc3504141797b44b88478ced87476
ToppCell	TCGA-Ovary-Primary_Tumor\|TCGA-Ovary / Sample_Type by Project: Shred V9	GBF1 SRPRA CHD4 GSK3A GSK3B	5.71e-05	106	172	5	14f548be39cec604fbdae0382cbf434fa4049840
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	GBF1 SRPRA CHD4 GSK3A GSK3B	5.71e-05	106	172	5	939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma\|TCGA-Ovary / Sample_Type by Project: Shred V9	GBF1 SRPRA CHD4 GSK3A GSK3B	5.71e-05	106	172	5	e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Mme_Fam114a1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TM6SF1 F2R TMEM132C KCNS3 GPRC5B	6.25e-05	108	172	5	4536cbe1748aee37f0a13648c5679fd592af6322
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150A TP53INP1 ZNF473 SDR42E1 PHYHD1 GOLGA8A	6.33e-05	176	172	6	2e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCell	Control-Lymphoid_P-Plasmablast\|Control / Disease group, lineage and cell class	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.33e-05	176	172	6	4b4416f342b732d2cc60133838728880326257d8
ToppCell	Control-Lymphoid_P\|Control / Disease group, lineage and cell class	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.33e-05	176	172	6	d895a6b295cd649273ff80ad7785a3e0ae4c728a
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 TP53INP1 IGHV3-13 IGHV3-7 NOXRED1 CD38	6.54e-05	177	172	6	c2b0fb5921eea24d248d6e6ccb57c29b0832602c
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.54e-05	177	172	6	4c434a7b7cc54cf4dac996bbc3f5124d9ef9a9cd
ToppCell	(2)_Plasma_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.54e-05	177	172	6	ed3c936bb69f9bc7291b4f6cde1d204078117c48
ToppCell	VE-plasma\|VE / Condition, Cell_class and T cell subcluster	IGHV3-48 IGHV3-7 GGH GLDC CD38 SCNN1B	6.54e-05	177	172	6	0c1cc0834de55717cb4f69d020339060ce2c9a03
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.54e-05	177	172	6	d746122bf8d208c3aa4d156e8c12d0a0e555c6e5
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TP53INP1 IGHV3-7 ESR2 F2R GLDC DYRK3	6.54e-05	177	172	6	b326376e879afef579b1b7094d756aaff0de270b
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TP53INP1 IGHV3-7 ESR2 F2R GLDC DYRK3	6.54e-05	177	172	6	393882f1bf7658a17e10a771b803339f16fb2e69
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.54e-05	177	172	6	fc40918825b7e1eb6861df59dfca944778a64b98
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	IGHV3-48 TP53INP1 IGHV3-13 IGHV3-7 NOXRED1 CD38	6.54e-05	177	172	6	111fb0707ff37ca631d85bb5a09e067ffe568eb8
ToppCell	VE-plasma-\|VE / Condition, Cell_class and T cell subcluster	IGHV3-48 IGHV3-7 GGH GLDC CD38 SCNN1B	6.54e-05	177	172	6	3a3c94cf30012e2aa266bc4d7fe772e45fa90f6d
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 TM4SF18 MAP4K2	6.74e-05	178	172	6	4ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 TM4SF18 MAP4K2	6.74e-05	178	172	6	c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.95e-05	179	172	6	837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 TM4SF18 MAP4K2	6.95e-05	179	172	6	abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 TM4SF18 MAP4K2	6.95e-05	179	172	6	0b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSPEAR MCTP1 TIE1 SCNN1B TM4SF18 MAP4K2	6.95e-05	179	172	6	ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCell	Healthy_Control-Lymphoid-T-NK\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	STYK1 SPNS3 F2R TMEM132C GPR68 SCART1	6.95e-05	179	172	6	4cd0bb3a99f85ff599b4b79a6a9ace3e51f8b296
ToppCell	PCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TSPEAR MCTP1 TIE1 SCNN1B TM4SF18 MAP4K2	6.95e-05	179	172	6	35fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCell	CD8+_Memory_T_cell-FLU-5\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	SDR42E1 PFKP DGAT2 GPR68 DENND6B GOLGA8A	6.95e-05	179	172	6	7f18dffa85285599662edbcd3f32ab42672bffb8
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.95e-05	179	172	6	494febe77c6d4e6a2c6f0928bbf4c84b0301f188
ToppCell	PBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	6.95e-05	179	172	6	b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 PTCHD3 TIE1 SCNN1B TM4SF18 GPRC5B	7.39e-05	181	172	6	b244ecaa442bbef51289d8ec574ef08fa9e96318
ToppCell	367C-Endothelial_cells-Endothelial-F_(Lymphatics)\|367C / Donor, Lineage, Cell class and subclass (all cells)	EPHB4 PTCHD3 TIE1 SCNN1B TM4SF18 GPRC5B	7.39e-05	181	172	6	dd79de8098edb385a0f85d0e9621503cdf76ec43
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	7.39e-05	181	172	6	f7b08f662eb77ee7a777c6525ddc3195046aaf65
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR1B CAMK1D CHRM4 KCNV1 MCTP1 KCNG1	7.62e-05	182	172	6	d41ff834b8fc1d0e23cac7ae261de5f72874e462
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLA2G4E CDKL1 TMEM178A SCNN1B SLC4A9 GPRC5B	7.62e-05	182	172	6	2ef6889321fd0104d277518d130e19143b3af41c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTR1B CAMK1D CHRM4 KCNV1 MCTP1 KCNG1	7.62e-05	182	172	6	6cde859edfe7607bd7ada89d20258413d06f4207
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-13 IGHV3-7 GGH CD38 SCNN1B	7.86e-05	183	172	6	a6866951866373a1029e04818f4a4a31278c409d
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDE3A ESR2 SLC52A3 NADSYN1 MCTP1 TIE1	7.86e-05	183	172	6	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 SCNN1B MAP4K2	7.86e-05	183	172	6	a90ffd9c50caa65f537a2e441e37655e1b622327
ToppCell	cellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGHV3-48 TP53INP1 IGHV3-13 IGHV3-7 GLDC CD38	7.86e-05	183	172	6	5ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B_plasma\|lymph-node_spleen / Manually curated celltypes from each tissue	IGHV3-48 IGHV3-13 IGHV3-7 GGH CD38 SCNN1B	7.86e-05	183	172	6	beadc69f511cf183e493cb445135f0748ab8b20e
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 SCNN1B MAP4K2	7.86e-05	183	172	6	13ad20ec140ef5b96fdace3369b5befc0f40bb76
ToppCell	367C-Lymphocytic-Plasma_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 TP53INP1 IGHV3-7 GGH CD38 SCNN1B	8.10e-05	184	172	6	14a5288d861260f63fbe0cbea3569cf643e7597e
ToppCell	10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells\|Liver / Manually curated celltypes from each tissue	IGHV3-48 TP53INP1 IGHV3-7 GGH CD38 SCNN1B	8.10e-05	184	172	6	6f70d8f8ab8362d51f8a58735d42223e06566397
ToppCell	367C-Lymphocytic-Plasma_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	IGHV3-48 TP53INP1 IGHV3-7 GGH CD38 SCNN1B	8.10e-05	184	172	6	fc708a5c8a7b19fab973c72dc4383a7d30f8b59a
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 NWD1 ANKUB1 WDR93 CC2D2A CFAP57	8.34e-05	185	172	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PDE3A ACRBP F2R CDKL1 OXTR BBS12	8.34e-05	185	172	6	709236097cbfc254796fcc69b5f5178b73dad9bd
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PDE3A ACRBP F2R CDKL1 OXTR BBS12	8.34e-05	185	172	6	af078a6c4a3e0b54b7d8ab7b30dcd06053ebfd28
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSPEAR MCTP1 TIE1 CD38 TM4SF18 MAP4K2	8.59e-05	186	172	6	5d94e6dd2c92e0c46badeb1e6eb54b69af855a66
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSPEAR TIE1 PTX3 CD38 TM4SF18 MAP4K2	8.59e-05	186	172	6	9d250d5ae7cf9129be05b41d70cb6c3a046c5f1e
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NOXRED1 SDR42E1 ARHGEF17 WDR93 TIE1 MAMDC2	8.59e-05	186	172	6	ffd4510b4435d9bf94c2ef14c629f73ab78c5d93
ToppCell	PCW_07-8.5-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TSPEAR MCTP1 TIE1 CD38 TM4SF18 MAP4K2	8.59e-05	186	172	6	1da52e13096dfe4eb08bd0e7461cb3809b3b3deb
ToppCell	Ciliated_cells-B-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	DNAH3 NWD1 TTC16 ANKUB1 WDR93 CFAP57	8.85e-05	187	172	6	bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SLC52A3 KCNC4 GLDC TMEM178A SCNN1B GPRC5B	8.85e-05	187	172	6	b7689e7f6511920cd2beff27389555fddf685f61
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PDE3A ESR2 CDK19 MCTP1 TIE1 ADGRE5	9.11e-05	188	172	6	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	systemic_lupus_erythematosus-flare-Hematopoietic-progenitor_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	NOXRED1 SDR42E1 ARHGEF17 WDR93 TIE1 MAMDC2	9.11e-05	188	172	6	c613c6c7b6de8ed514253c9f9b8622c56fcc1452
ToppCell	cellseq2-Immune-Lymphocytic_B-Lymphocytic_B-Plasma\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	IGHV3-48 TP53INP1 IGHV3-7 GLDC CD38 SCNN1B	9.11e-05	188	172	6	33360f1c30315d9772731c9067834dc059172b79
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PDE3A CDK19 TM6SF1 JAG2 MCTP1 TIE1	9.38e-05	189	172	6	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|normal_Lung / Location, Cell class and cell subclass	EPHB4 TIE1 PTX3 SCNN1B TM4SF18 GPRC5B	9.66e-05	190	172	6	2185db6007404a2b22325f91460dd17635be9bba
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ZSWIM8 MMS22L MCTP1 WDR11 TBCK FCHSD1	9.66e-05	190	172	6	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLR9 CDKL1 GGH MAP4K1 CD37 CD38	9.94e-05	191	172	6	10644258b97f9c99eb0e199b64b970f6b986aa41
ToppCell	P07-Endothelial-large_vessel_endothelial_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EPHB4 PDE3A ESR2 TM6SF1 MCTP1 TIE1	9.94e-05	191	172	6	d162917816dd2e4767c97447c1cddae9397713ab
Drug	W-A-Y	HTR1B HTR1D ESR2 F2R OXTR UHMK1	3.53e-06	56	168	6	CID000004368
Drug	carbamazepine	HTR1B HTR1D TSPEAR SLC13A2 GSK3A GSK3B SCNN1B SCNN1D ADGRE5	7.59e-06	179	168	9	CID000002554
Drug	NSC105327	CDK8 CDK19 GSK3A GSK3B CDK2 CDK3	1.31e-05	70	168	6	CID005318433
Drug	pyraclofos	KCNG3 KCNV1 KCNC4 KCNF1 KCNG1 SCNN1B KCNS3	1.39e-05	106	168	7	CID000093460
Drug	AC1L8MIY	TP53INP1 KCNF1 KCNG1	2.15e-05	8	168	3	CID000428933
Drug	BW 737C	HTR1B HTR1D UHMK1	2.15e-05	8	168	3	CID000132241
Drug	5-fluoro-alpha-methyltryptamine	HTR1B HTR1D F2R	2.15e-05	8	168	3	CID000012834
Drug	melantonin	AANAT HTR1B HTR1D	3.21e-05	9	168	3	CID000077899
Drug	6,7-DHT	HTR1B HTR1D	5.41e-05	2	168	2	CID000039719
Drug	JMC-181	HTR1B HTR1D	5.41e-05	2	168	2	CID000134385
Drug	(-)-Ircinol A	GSK3A GSK3B	5.41e-05	2	168	2	CID005276610
Drug	AC1O6ZTU	GSK3A CDK2	5.41e-05	2	168	2	CID006539561
Drug	AC1O6ZTW	GSK3A CDK2	5.41e-05	2	168	2	CID006539562
Drug	AC1O6ZTY	GSK3A CDK2	5.41e-05	2	168	2	CID006539563
Drug	AC1O6ZU0	GSK3A CDK2	5.41e-05	2	168	2	CID006539564
Drug	AC1L8KDY	GSK3A GSK3B	5.41e-05	2	168	2	CID000382949
Drug	N,N-dipropyl-6,7-ADTN	HTR1B HTR1D	5.41e-05	2	168	2	CID000125246
Drug	manzamine A N-oxide	GSK3A GSK3B	5.41e-05	2	168	2	CID006480355
Drug	Frovatriptan	HTR1B HTR1D	5.41e-05	2	168	2	DB00998
Drug	Almotriptan	HTR1B HTR1D	5.41e-05	2	168	2	DB00918
Drug	Me-6-BIO	GSK3A GSK3B	5.41e-05	2	168	2	CID006538821
Drug	xestomanzamine A	GSK3A GSK3B	5.41e-05	2	168	2	CID006481130
Drug	PD 128483	HTR1B HTR1D	5.41e-05	2	168	2	CID000130792
Drug	naratriptan	HTR1B HTR1D	5.41e-05	2	168	2	ctd:C106783
Drug	3-phenethyl-PP	HTR1B HTR1D	5.41e-05	2	168	2	CID000167838
Drug	DS121	HTR1B HTR1D	5.41e-05	2	168	2	CID000005119
Drug	ircinal	GSK3A GSK3B	5.41e-05	2	168	2	CID005270588
Drug	BRL 15572	HTR1B HTR1D	5.41e-05	2	168	2	ctd:C108532
Drug	N-(3-(2-dimethylamino)ethoxy-4-methoxyphenyl)-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-(1,1'-biphenyl)-4-carboxamide	HTR1B HTR1D	5.41e-05	2	168	2	ctd:C108531
Drug	PD 120697	HTR1B HTR1D	5.41e-05	2	168	2	CID000194776
Drug	R-E 244	HTR1B HTR1D	5.41e-05	2	168	2	CID000168237
Drug	L 694247	HTR1B HTR1D	5.41e-05	2	168	2	ctd:C085632
Drug	tramazoline	AANAT HTR1B HTR1D	6.23e-05	11	168	3	CID000005524
Drug	alniditan	HTR1B HTR1D UHMK1	6.23e-05	11	168	3	CID000066004
Drug	MPEP	HTR1B HTR1D GRID2 GSK3A GSK3B	7.48e-05	59	168	5	CID003025961
Drug	Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; PC3; HT_HG-U133A	HTR1D CDK19 VPS16 ARHGEF17 TAOK2 PTX3 UGCG GPRC5B	8.65e-05	190	168	8	6697_UP
Drug	thapsigargin; Down 200; 0.1uM; MCF7; HT_HG-U133A	MED20 GPR19 ERCC6L JAG2 KCNS3 ADGRE5 GPRC5B CDK2	8.65e-05	190	168	8	7053_DN
Drug	trimethoprim	ARHGEF17 TAOK2 KCNG1 SCNN1B SCNN1D TAOK1	9.38e-05	99	168	6	CID000005578
Drug	AC1L1E22	GSK3A GSK3B TMEM132D CDK2 CDK3	9.49e-05	62	168	5	CID000002607
Drug	trimetrexate	STK36 ABCB5 GGH TMEM132D	9.90e-05	33	168	4	CID000005582
Drug	aloisine A	GSK3A GSK3B CDK2	1.07e-04	13	168	3	CID005326843
Drug	5-methoxyindole	AANAT GSK3A GSK3B	1.07e-04	13	168	3	CID000013872
Drug	CT-5	HTR1B HTR1D UHMK1	1.07e-04	13	168	3	CID003034918
Drug	clozapine; Down 200; 10uM; MCF7; HT_HG-U133A	DNAH3 ZNF473 RNF123 OXTR KCNG1 PGP GPRC5B CDK3	1.07e-04	196	168	8	6988_DN
Drug	Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; HL60; HT_HG-U133A	ANKFY1 ZNF473 CTC1 GSK3A KCNG1 DNAH17 PGP MAP4K2	1.11e-04	197	168	8	2532_DN
Drug	ICI 182,780; Up 200; 0.01uM; MCF7; HG-U133A	GPR3 ZSWIM8 DNAH3 WDR18 CHD3 GSK3A PGP ASCC3	1.15e-04	198	168	8	310_UP
Drug	zolmitriptan	HTR1B HTR1D	1.62e-04	3	168	2	ctd:C089750
Drug	Iskedyl	HTR1B HTR1D	1.62e-04	3	168	2	CID000196331
Drug	5-benzyloxyindole	GSK3A GSK3B	1.62e-04	3	168	2	CID000014624
Drug	Thiethylperazine Malate	HTR1B HTR1D	1.62e-04	3	168	2	CID003085006
Drug	rizatriptan	HTR1B HTR1D	1.62e-04	3	168	2	ctd:C093622
Drug	piperazine-1-carboxamide	HTR1B HTR1D	1.62e-04	3	168	2	CID000258192
Drug	Rizatriptan	HTR1B HTR1D	1.62e-04	3	168	2	DB00953
Drug	nitroguanil	GSK3A GSK3B	1.62e-04	3	168	2	CID000005822
Drug	N-propylpiperidine	HTR1B HTR1D	1.62e-04	3	168	2	CID000021644
Drug	diinosine tetraphosphate	HTR1B HTR1D	1.62e-04	3	168	2	CID006324650
Drug	AC1OCF7F	HTR1B HTR1D	1.62e-04	3	168	2	CID003035836
Drug	AC1LA61L	TAOK2 TMEM132D	1.62e-04	3	168	2	CID000482116
Drug	PD 118440	HTR1B HTR1D	1.62e-04	3	168	2	CID000194775
Drug	ORG 20091	HTR1B HTR1D	1.62e-04	3	168	2	CID000132371
Drug	Emd-23448	HTR1B HTR1D	1.62e-04	3	168	2	CID006917760
Drug	spirilene	HTR1B HTR1D	1.62e-04	3	168	2	CID006436870
Drug	L-646,462	HTR1B HTR1D	1.62e-04	3	168	2	CID000145990
Drug	8-((4-chlorophenyl)thio)cyclic-3',5'-GMP	ARHGEF17 SCNN1B SCNN1D	1.68e-04	15	168	3	ctd:C055656
Disease	Glioblastoma Multiforme	RPS6KA3 STYK1 JAG2 STKLD1 NLK CDK2 CDK3	3.40e-06	111	167	7	C1621958
Disease	developmental and epileptic encephalopathy 87 (implicated_via_orthology)	CDK8 CDK19	3.18e-05	2	167	2	DOID:0112221 (implicated_via_orthology)
Disease	ciliopathy (implicated_via_orthology)	WDR11 MAP4K1 CC2D2A MAP4K2	7.72e-05	40	167	4	DOID:0060340 (implicated_via_orthology)
Disease	Ischemic stroke, coronary artery disease	EPG5 TMEM132D RPTOR CRLF3 KCNS3	1.81e-04	92	167	5	EFO_0001645, HP_0002140
Disease	Intellectual Disability	CDK8 TREX1 CHD3 POGZ MED13L KMT2C AGMO TAOK1 ASCC3 DYNC1H1	2.46e-04	447	167	10	C3714756
Disease	Depressive disorder	AANAT HTR1B HTR1D CSMD2 GSK3A GSK3B RNF123 OXTR	2.54e-04	289	167	8	C0011581
Disease	hereditary spastic paraplegia 76 (implicated_via_orthology)	CAPN1 CAPN2	3.15e-04	5	167	2	DOID:0110821 (implicated_via_orthology)
Disease	depressive symptom measurement, herpes virus seropositivity	HTR1B TMEM132C	3.15e-04	5	167	2	EFO_0007006, EFO_0007036
Disease	Colorectal Carcinoma	DNAH3 ABCA12 ESR2 ABCB5 TSPEAR GRID2 SPNS3 TLR9 GGH KMT2C CHD5 SCNN1B	6.88e-04	702	167	12	C0009402
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	ZDHHC18 HTR1B CSMD2 TMEM132D	7.16e-04	71	167	4	EFO_0004735, EFO_0007965
Disease	hypokalemic periodic paralysis (implicated_via_orthology)	SCNN1B SCNN1D	8.72e-04	8	167	2	DOID:14452 (implicated_via_orthology)
Disease	generalized anxiety disorder (implicated_via_orthology)	HTR1B HTR1D	8.72e-04	8	167	2	DOID:14320 (implicated_via_orthology)
Disease	ribose-5-phosphate measurement, ribulose-5-phosphate measurement	GRID2 TMEM132C	8.72e-04	8	167	2	EFO_0010529, EFO_0010530
Disease	corticobasal degeneration disorder	TSPEAR SPPL2C	1.12e-03	9	167	2	MONDO_0022308
Disease	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 measurement	CD38 CC2D2A	1.12e-03	9	167	2	EFO_0008014
Disease	Carcinoma, Transitional Cell	ESR2 GGH KMT2C	1.62e-03	41	167	3	C0007138
Disease	Pancreatic Ductal Adenocarcinoma	ABCA12 ABCB5	1.69e-03	11	167	2	C1335302
Disease	osteosarcoma, overall survival	GLDC AGMO	2.02e-03	12	167	2	EFO_0000637, EFO_0000638
Disease	Parkinson disease	GBF1 CTC1 CD38 DNAH17 KCNS3 SPPL2C KPNA1	2.43e-03	321	167	7	MONDO_0005180
Disease	calcium measurement	PDE3A CAMK1D ICE2 ESR2 DGKD F2R GGH SPPL2A ASCC3 KPNA1	3.18e-03	628	167	10	EFO_0004838
Disease	Mental Depression	AANAT HTR1B CSMD2 GSK3B RNF123 OXTR	3.34e-03	254	167	6	C0011570
Disease	Ciliopathies	USH1G SCNN1B CC2D2A BBS12	3.59e-03	110	167	4	C4277690
Disease	central nervous system disease (implicated_via_orthology)	TAOK2 TAOK1	3.63e-03	16	167	2	DOID:331 (implicated_via_orthology)
Disease	Unipolar Depression	HTR1B ESR2 GSK3A GSK3B OXTR PTX3	3.67e-03	259	167	6	C0041696
Disease	Multiple congenital anomalies	GSK3B NADSYN1	4.10e-03	17	167	2	C0000772
Disease	ischemia (implicated_via_orthology)	SCNN1B SCNN1D	4.10e-03	17	167	2	DOID:326 (implicated_via_orthology)
Disease	spinal stenosis	PDE3A AGMO	4.10e-03	17	167	2	EFO_0007490
Disease	Schizophrenia	ESR2 CHD4 CSMD2 CHRM4 GSK3A GSK3B JAG2 OXTR WDR11 UHMK1 KCNS3 KPNA1	4.59e-03	883	167	12	C0036341
Disease	systemic lupus erythematosus (is_implicated_in)	TREX1 ESR2 TLR9	5.27e-03	62	167	3	DOID:9074 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LSFLVSFGANIWCLD	USH1G	81	Q495M9
GAVVCDLWLALDYVV	CHRM4	101	P08173
LFLGSVLCEVNWVSV	EPG5	2086	Q9HCE0
DGSLWETVARALSCL	BRAT1	276	Q6PJG6
GIWVATFCLVLVATE	SLC4A9	501	Q96Q91
TLGQVVCDFWLSSDI	HTR1B	116	P28222
DIWAIGCIFAELLTS	CDK19	216	Q9BWU1
ADCTWTILAELGDTI	CSMD2	226	Q7Z408
VLSCELIDLDLSWLG	CTC1	141	Q2NKJ3
IDQAILGSIEWACLV	CHD5	831	Q8TDI0
AFVWRLSDGELLFEC	AAMP	116	Q13685
EIVFSICIAFWGVRS	AGMO	421	Q6ZNB7
SVLAQDIGWFDSCDI	ABCB5	146	Q2M3G0
DTTSFGWLCCLILAD	ABCA12	1246	Q86UK0
AACLCLAEVGITFWV	ALG3	46	Q92685
CEDVRVSGWLQTEFL	ACRBP	451	Q8NEB7
SVDIWAIGCVFAELL	CDKL4	181	Q5MAI5
WLFSIFGNSLVCLVI	GPR19	76	Q15760
TAIAQLFLLGCTWVF	ADGRE5	741	P48960
NGAWLDSITCLLSEL	DNHD1	2091	Q96M86
WGTDEVKFLTVLCSR	ANXA4	186	P09525
ALGDCWLLAAIASLT	CAPN1	111	P07384
WLECVCVVTFDLELG	DENND6B	41	Q8NEG7
LVGAWSSAVEECLHL	BBS12	91	Q6ZW61
EDTLLGYLADDLTWC	CD38	146	P28907
VLADVCWALSYLSDG	KPNA5	271	O15131
QLVVSGSEDALLCLW	NWD1	1401	Q149M9
TSLVRACWNELFTLG	NR2C2	416	P49116
SGIIEAICIGWFTAE	KCNG3	221	Q8TAE7
KSFWDCGLVALDDIT	MAMDC2	476	Q7Z304
YNELCDVWALGITAI	MAP4K2	191	Q12851
ALLVCEELLWVGTSA	ARHGEF17	1926	Q96PE2
LAASWGLEETVQCLL	ANKFY1	776	Q9P2R3
DAAATGSLAELCWLV	ESPNL	76	Q6ZVH7
FELCDALVLLWVQSS	MDN1	2691	Q9NU22
AIDIQALFDSTGTCW	KMT2C	236	Q8NEZ4
LSWLAIVALCVFTAI	MCTP1	916	Q6DN14
DWSILLGECSLQTIS	MED13L	1911	Q71F56
CATEEEVWEFLGLLG	MAGEB6	301	Q8N7X4
ELSLFDQVRLLESCW	ESR2	321	Q92731
KSDIWAVGCVIFELL	NEK9	231	Q8TD19
LLCWASLAAALEETL	EPHB4	6	P54760
SWVFLVAILEGVQCE	IGHV3-7	6	P01780
VISIIQLFGWDDIIC	MMS22L	766	Q6ZRQ5
VLCGAFSVLWLACVV	JAG2	1086	Q9Y219
DAACDIWSLGVLLYT	RPS6KA3	596	P51812
AASAELVIGWCIFGL	LMBRD1	6	Q9NUN5
QFLLTAAEDGCLFTW	CFAP57	651	Q96MR6
SWVFLVAILEGVQCE	IGHV3-13	6	P01766
CWVFLVAILEGVQCE	IGHV3-48	6	P01763
LLEILEYVCISWFTG	KCNV1	241	Q6PIU1
DLSLWACIAGTVLLV	GRID2	566	O43424
AGVVLSCLAAATWLV	PDE3A	191	Q14432
ADVDTLLFDCDGVLW	PGP	26	A6NDG6
LLFDCDGVLWRGETA	PGP	31	A6NDG6
LVSALACGADWVFLP	PFKP	226	Q01813
REVVFDWLLDQSCGS	CRLF3	411	Q8IUI8
NDSWIFALAVLLCST	GBP6	111	Q6ZN66
VLEGVEIACIAWFTG	KCNS3	221	Q9BQ31
EIACIAWFTGELAVR	KCNS3	226	Q9BQ31
VESVCVGWFSLEFLL	KCNG1	271	Q9UIX4
LSFCDTYTVWDLLLG	NALF2	196	O75949
VETDLLQWCLESGSI	NAGS	241	Q8N159
AIDIWSVGCIFAELL	NLK	321	Q9UBE8
EFILLGLSSDWCTQI	OR2F2	11	O95006
SLREVADGVFDCWAV	OXTR	176	P30559
CILSEFWVLSIASAI	PRSS54	71	Q6PEW0
SSGICTDFWDLLVKL	HUWE1	3381	Q7Z6Z7
IATLAVVLGAFAACW	GPR3	246	P46089
FTCLAIWALAIAGVV	F2R	221	P25116
VSLCDLDAIWGIVVE	GPRC5B	46	Q9NZH0
TDFWGLLIETCLGDE	PLA2G4E	476	Q3MJ16
TVFGAWRCLLDATVA	FCHSD1	81	Q86WN1
TTAVDIWSIGCIFAE	CDK3	181	Q00526
YGVEALTESELCRLW	ICE2	781	Q659A1
IDVWSAGCVLAELLL	GSK3A	301	P49840
GICDLWSTSDQFLDL	CC2D2A	1346	Q9P2K1
SRDSECFVWDGLLVF	SDR42E1	361	Q8WUS8
LIYGCAVTAEDLDTW	DNAH17	1006	Q9UFH2
DGCWELIRDSFLEII	DNAH3	506	Q8TD57
LALEEQCLALSLDWS	DPH7	136	Q9BTV6
WGTCLGFEELSLLIS	GGH	131	Q92820
VWAIGCVFAELLSGV	CDKL1	186	Q00532
VVLCGLDWALYSIFD	DCST1	471	Q5T197
ALGSIRWACLVVDEA	CHD3	871	Q12873
SSIDVWSAGCVLAEL	GSK3B	236	P49841
FGQILCDIWLSSDIT	HTR1D	106	P28221
EPISECFVASLIIGW	UGCG	291	Q16739
GTEEVAAWLEHLSLC	DGKD	1146	Q16760
LESICLLLGESTTDW	DYNC1H1	3321	Q14204
DDWATLFTLLECIGS	GBF1	1261	Q92538
STAVDIWSLGCIFAE	CDK2	181	P24941
EILESECVLYTGWIE	BLID	16	Q8IZY5
ALGDCWLLAAIASLT	CAPN2	101	P17655
DIWAIGCIFAELLTS	CDK8	216	P49336
ILGSIDWACLIVDEA	CHD4	861	Q14839
ALFWCTEALPLAVTA	SLC13A2	46	Q13183
SCVISSGLDDLISIW	SCAP	1171	Q12770
CLIEFGEIIIDFVWI	SCNN1B	536	P51168
CSLWFGASVLSLLEL	SCNN1D	696	P51172
EEYTQLARECGLWLS	NIT1	111	Q86X76
DIWSFGCILAELLTG	DYRK3	391	O43781
AVEDATLENGCLWFI	PHYHD1	176	Q5SRE7
CFGIWILIDKTSFVS	CD37	31	P11049
WVLSFLVLGVACSAI	DGAT2	76	Q96PD7
TDCLEGLLSRTFQWL	PTCHD3	116	Q3KNS1
ELWSLFDFACQGSLL	ERCC6L	266	Q2NKX8
ILFCALWSAVLAENS	PTX3	6	P26022
WACSAGHTEIVEFLL	PSMD10	46	O75832
PCVVASDCWSLLLEF	MED20	146	Q9H944
ADLVSWADVIFLCCL	NOXRED1	131	Q6NXP6
VLLLVRSVWEASCDF	GPR68	246	Q15743
CDIWSLGITAIELAE	MAP4K1	196	Q92918
RIGELEWSLCAVAAT	GOLGA8A	196	A7E2F4
CWETLLDVISALILG	UTP20	361	O75691
EVLIVASWVLFSGCL	SLC52A3	396	Q9NQ40
SLGWFEEGCLVAFII	AANAT	81	Q16613
EEGCLVAFIIGSLWD	AANAT	86	Q16613
LGLCVAELELLSSWF	TMEM132C	191	Q8N3T6
LCVAELELLSSWFSP	TMEM132D	191	Q14C87
GAALCEWVCVIDILI	TMEM150A	206	Q86TG1
GCIVATVSFFWEESL	TMEM178A	191	Q8NBL3
WLLFVSDTDVLADAC	KPNA1	261	P52294
WCDVVLAILADGTVL	POGZ	1156	Q7Z3K3
LTSRDGAWFLEELCS	SMG1	2796	Q96Q15
LLASLCATVIIFWVA	SPPL2C	326	Q8IUH8
VDVWSLGITCIELAE	TAOK1	206	Q7L7X3
VDVWSLGITCIELAE	TAOK2	206	Q9UL54
VAGWNLSFSLFIICI	OR5M8	201	Q8NGP6
WEVSSGELLLSVLFD	WDR18	201	Q9BV38
YELLGSDILTCQWDL	SEZ6L2	676	Q6UXD5
AVDCWSIGVIAYILL	CAMK1D	201	Q8IU85
CLGETFATELGWLLL	STRC	1356	Q7RTU9
LVFIWAKILAVDSSC	RPTOR	491	Q8N122
ADLWSVGCILYELAV	STK36	181	Q9NRP7
YGSEEEAFWLLVALC	TBC1D9B	606	Q66K14
LKDSWSLADVGISFC	ANKUB1	56	A6NFN9
AVSDRWLGAEAVCII	ASCC3	1271	Q8N3C0
GLSVAIWTDLFLSCL	TMEM270	121	Q6UE05
DVAQGDLLSFLWTCR	STYK1	196	Q6J9G0
EAESRIFWLGLIACS	TVP23C	121	Q96ET8
FYDGQLVLTSDIWLC	USP45	71	Q70EL2
LGELLLSCNWAVVAD	SPNS3	376	Q6ZMD2
GRFLTDSSIWIQCLE	TM4SF18	136	Q96CE8
DEALSWDCFALSLLA	TLR9	811	Q9NR96
AEASCGVFWLLSLLG	STKLD1	521	Q8NE28
LVLADSGFWECRVST	TIE1	416	P35590
AWAAGDIVSCLIDLD	RNF123	191	Q5XPI4
VLSLCSEQDIEGWLE	SNX18	26	Q96RF0
WILVDFIDTCTGFSA	TP53INP1	31	Q96A56
AQDCSWFLAVLLATL	SERINC4	216	A6NH21
FLSGLCIAVAVVWAV	SPPL2A	291	Q8TCT8
VVSLGWSAEEELLCV	VPS16	86	Q9H269
AGERLVAVDFSATWC	TXNDC2	466	Q86VQ3
WVLGCTLALVVSAFF	ZNRF4	256	Q8WWF5
WLLENGFSVLIAACD	SRPRA	441	P08240
WVVVALCSNGTFREL	SCART1	121	Q4G0T1
EVTWGTVCDAALDLA	SCART1	246	Q4G0T1
SACGLDIVLWSFLLA	POPDC2	71	Q9HBU9
DVWSLGIILFELCVG	TBCK	186	Q8TEA7
AALTILVECWDGHLT	ZSWIM8	1321	A7E2V4
YLVLACEDGVLTLWD	WDR93	426	Q6P2C0
CLEQADWETAVLLFS	TTC16	71	Q8NEE8
ILTCSALDWEFFSVG	TSPEAR	581	Q8WU66
CEVKGIEWTSLTSFL	WDR11	516	Q9BZH6
TAEGDVLALLSICQW	TREX1	196	Q9NSU2
DTECTSAVDLWSLGI	UHMK1	216	Q8TAS1
CRTLEEVTASLGWDL	SNRNP48	26	Q6IEG0
ELVICFFSIWSILGL	ZDHHC18	281	Q9NUE0
IALLVLEEEESAFWC	TBC1D2	721	Q9BYX2
DSWTIVGVAALILFL	TM6SF1	31	Q9BZW5
NFGEACIEDTWLDSL	ZNF473	111	Q8WTR7
LDDLLWIFGCESSAE	GLDC	481	P23378
WIFGCESSAELVAES	GLDC	486	P23378
LTYIEGVCVLWFTLE	KCNC4	281	Q03721
TLENVETACIGWFTL	KCNF1	221	Q9H3M0
VPFGDAVLVTWDTCI	NADSYN1	156	Q6IA69