Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	methyl-CpG binding	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	4.59e-06	31	161	5	GO:0008327
GeneOntologyBiologicalProcess	branchiomotor neuron axon guidance	MYCBP2 NRP2 SEMA3A	1.54e-05	7	159	3	GO:0021785
GeneOntologyBiologicalProcess	DNA methylation-dependent constitutive heterochromatin formation	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	2.18e-05	44	159	5	GO:0006346
GeneOntologyBiologicalProcess	notochord regression	GLI1 GLI2	5.91e-05	2	159	2	GO:0060032
GeneOntologyBiologicalProcess	facultative heterochromatin formation	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	6.51e-05	55	159	5	GO:0140718
Domain	MeCpG-bd_2/3_C_dom	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.74e-07	7	159	4	IPR025884
Domain	MBD2/MBD3_p55-bd	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.74e-07	7	159	4	IPR032343
Domain	MBDa	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.74e-07	7	159	4	PF16564
Domain	MBD_C	MBD3L5 MBD3L2 MBD3L3 MBD3L4	1.74e-07	7	159	4	PF14048
Domain	-	MANBA MYCBP2 LAMC3 SSPOP NRP2 GLB1	3.68e-05	73	159	6	2.60.120.260
Domain	CUB	CSMD2 NRP2 MEGF8 DMBT1 CSMD1	5.92e-05	49	159	5	PF00431
Domain	CUB	CSMD2 NRP2 MEGF8 DMBT1 CSMD1	6.53e-05	50	159	5	SM00042
Domain	VIT_2	VWA5B2 VWA5B1	7.20e-05	2	159	2	PF13757
Domain	-	CSMD2 NRP2 MEGF8 DMBT1 CSMD1	7.90e-05	52	159	5	2.60.120.290
Domain	CUB	CSMD2 NRP2 MEGF8 DMBT1 CSMD1	8.66e-05	53	159	5	PS01180
Domain	-	MARS1 DALRD3 IARS2	9.50e-05	11	159	3	1.10.730.10
Domain	CUB_dom	CSMD2 NRP2 MEGF8 DMBT1 CSMD1	1.23e-04	57	159	5	IPR000859
Domain	Galactose-bd-like	MANBA MYCBP2 LAMC3 SSPOP NRP2 GLB1	1.52e-04	94	159	6	IPR008979
Domain	Prot-tyrosine_phosphatase-like	MTMR8 TNS2 DUSP15 PTPN21 MTMR7 PTPRB	2.02e-04	99	159	6	IPR029021
Domain	tRNAsynth_Ia_anticodon-bd	MARS1 DALRD3 IARS2	2.56e-04	15	159	3	IPR009080
Domain	Tyr_Pase_AS	MTMR8 DUSP15 PTPN21 MTMR7 PTPRB	3.96e-04	73	159	5	IPR016130
Domain	ZF_ZZ_2	DTNB MIB2 EP300	4.50e-04	18	159	3	PS50135
Domain	ZF_ZZ_1	DTNB MIB2 EP300	4.50e-04	18	159	3	PS01357
Domain	ZZ	DTNB MIB2 EP300	4.50e-04	18	159	3	PF00569
Domain	Znf_ZZ	DTNB MIB2 EP300	5.31e-04	19	159	3	IPR000433
Domain	ZnF_ZZ	DTNB MIB2 EP300	5.31e-04	19	159	3	SM00291
Domain	-	MTMR8 PSD3 TNS2 PTPN21 ARHGEF10L MTMR7 OSBPL10 FGD1 PLEKHA7 PHLDB2 ANKS1A	5.35e-04	391	159	11	2.30.29.30
Domain	NFAT	NFATC1 NFATC2	7.08e-04	5	159	2	IPR008366
Domain	TYR_PHOSPHATASE_1	MTMR8 DUSP15 PTPN21 MTMR7 PTPRB	8.39e-04	86	159	5	PS00383
Domain	PH_dom-like	MTMR8 PSD3 TNS2 PTPN21 ARHGEF10L MTMR7 OSBPL10 FGD1 PLEKHA7 PHLDB2 ANKS1A	1.08e-03	426	159	11	IPR011993
Domain	-	TNS2 DUSP15 PTPN21 MTMR7 PTPRB	1.14e-03	92	159	5	3.90.190.10
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	VWA5B2 MYCBP2 PHF12 PIEZO1 MTMR8 LAMC3 MIB2 ITGA5 ZNF236 NPHP4 PRAG1 ARHGEF10L KMT2C CELSR1 INTS5 PSME4 RPAP1 MEGF8 NFATC1 GLI1 NEK8 PAXIP1 LRRC56 NLRC5 FLCN BAMBI PCNX1 DISP2 TNKS1BP1 ULK2 EP300 ELL PRRC2B ZNF687	3.52e-18	1105	166	34	35748872
Pubmed	MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	1.39e-11	6	166	5	12504854
Pubmed	Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	1.39e-11	6	166	5	18942147
Pubmed	MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.	MBD3L5 MBD3L2 MBD3L3 MBD3L4 MBD3L2B	6.74e-09	15	166	5	15701600
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PHYKPL MYCBP2 MARS1 DTNB SAMD4B E2F3 IQCN ZNF236 UBN2 SSPOP MAP3K12 KMT2C PTPRB NFATC1 MICAL2 GLI2 TBCK NLRC5 AFF1 TNFRSF19 LIMCH1 CSMD1 CFAP69 EP300 ANKS1A	4.64e-08	1489	166	25	28611215
Pubmed	Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.	FAT4 ITGA9 NRP2 CELSR1	6.19e-08	9	166	4	28705793
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CASP8AP2 PHF12 PIEZO1 RNF44 E2F3 ARHGEF10L KMT2C INTS5 PSME4 CPNE1 PCNX1 TNKS1BP1 ZNF687 ANKS1A	2.86e-07	529	166	14	14621295
Pubmed	Hepatitis C virus core protein regulates p300/CBP co-activation function. Possible role in the regulation of NF-AT1 transcriptional activity.	NFATC1 NFATC2 EP300	4.26e-07	4	166	3	15380363
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	ILK MYCBP2 SAMD4B PSD3 PTPN21 PRAG1 E2F8 MEGF8 OSBPL10 NHS TNKS1BP1 NR3C2 LIMCH1 USP54 PLEKHA7 PHLDB2 ANKS1A	8.97e-07	861	166	17	36931259
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MYCBP2 PHF12 SAMD4B IQCN RIF1 INTS5 RPAP1 AFF1 TNKS1BP1 LIMCH1 TACC3 CTPS1 MRTFA PHLDB2 ZNF687 ANKS1A	1.06e-06	774	166	16	15302935
Pubmed	Regulation of T cell activation by HIV-1 accessory proteins: Vpr acts via distinct mechanisms to cooperate with Nef in NFAT-directed gene expression and to promote transactivation by CREB.	NFATC1 NFATC2 EP300	2.11e-06	6	166	3	12788643
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	FAT4 GALNT3 PHF12 ADAM30 ITGA5 CSMD2 LMOD2 MEGF8 PAXIP1 TRIM8 FLCN EP300 PRRC2B ZNF687	2.59e-06	638	166	14	31182584
Pubmed	Mechanically activated ion channel PIEZO1 is required for lymphatic valve formation.	PIEZO1 ITGA9 NFATC2	5.88e-06	8	166	3	30482854
Pubmed	Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis.	SOX5 RELN GLI1 GLI2	6.89e-06	26	166	4	26387942
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	FAT4 MANBA GALNT3 MYCBP2 PIEZO1 LAMC3 ITGA5 NRP2 DHX15 SEMA3A CELSR1 GLB1 MEGF8 MICAL2 FLCN TNKS1BP1 SLC37A4 PIGO	1.91e-05	1201	166	18	35696571
Pubmed	Relative Levels of Gli1 and Gli2 Determine the Response of Ventral Neural Stem Cells to Demyelination.	GLI1 GLI2	2.26e-05	2	166	2	33125874
Pubmed	Nuclear Factor of Activated T Cells-dependent Down-regulation of the Transcription Factor Glioma-associated Protein 1 (GLI1) Underlies the Growth Inhibitory Properties of Arachidonic Acid.	NFATC1 GLI1	2.26e-05	2	166	2	26601952
Pubmed	NFAT2 Isoforms Differentially Regulate Gene Expression, Cell Death, and Transformation through Alternative N-Terminal Domains.	NFATC1 NFATC2	2.26e-05	2	166	2	26483414
Pubmed	Activin-βC modulates gonadal, but not adrenal tumorigenesis in the inhibin deficient mice.	INHA INHBC	2.26e-05	2	166	2	25869398
Pubmed	Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells.	NFATC1 NFATC2	2.26e-05	2	166	2	17438271
Pubmed	Maintenance of Taste Organs Is Strictly Dependent on Epithelial Hedgehog/GLI Signaling.	GLI1 GLI2	2.26e-05	2	166	2	27893742
Pubmed	NFAT1 and NFAT2 Differentially Regulate CTL Differentiation Upon Acute Viral Infection.	NFATC1 NFATC2	2.26e-05	2	166	2	30828328
Pubmed	Expression of Hedgehog Pathway Mediator GLI Represents a Negative Prognostic Marker in Human Acute Myeloid Leukemia and Its Inhibition Exerts Antileukemic Effects.	GLI1 GLI2	2.26e-05	2	166	2	25745035
Pubmed	Unique and overlapping GLI1 and GLI2 transcriptional targets in neoplastic chondrocytes.	GLI1 GLI2	2.26e-05	2	166	2	30695055
Pubmed	Prostacyclin signaling boosts NADPH oxidase 4 in the endothelium promoting cytoprotection and angiogenesis.	NOX4 PTGIR	2.26e-05	2	166	2	24450852
Pubmed	Membrane microdomain organization, calcium signal, and NFAT activation as an important axis in polarized Th cell function.	NFATC1 NFATC2	2.26e-05	2	166	2	23184643
Pubmed	Human GLI2 and GLI1 are part of a positive feedback mechanism in Basal Cell Carcinoma.	GLI1 GLI2	2.26e-05	2	166	2	12165851
Pubmed	Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes.	NFATC1 EP300	2.26e-05	2	166	2	15117818
Pubmed	The GLI gene is a member of the Kruppel family of zinc finger proteins.	GLI1 GLI2	2.26e-05	2	166	2	2832761
Pubmed	GLI1/GLI2 functional interplay is required to control Hedgehog/GLI targets gene expression.	GLI1 GLI2	2.26e-05	2	166	2	32766732
Pubmed	Nuclear factor of activated T cells 1 and 2 are required for vertebral homeostasis.	NFATC1 NFATC2	2.26e-05	2	166	2	32329053
Pubmed	Loss of CSMD1 or 2 may contribute to the poor prognosis of colorectal cancer patients.	CSMD2 CSMD1	2.26e-05	2	166	2	24408017
Pubmed	NFAT1 and NFAT2 are positive regulators of IL-4 gene transcription.	NFATC1 NFATC2	2.26e-05	2	166	2	12355451
Pubmed	A Critical Function for the Transcription Factors GLI1 and GLI2 in the Proliferation and Survival of Human Mast Cells.	GLI1 GLI2	2.26e-05	2	166	2	35251038
Pubmed	GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter.	GLI1 GLI2	2.26e-05	2	166	2	15175043
Pubmed	RANK- NFATc1 signaling forms positive feedback loop on rank gene expression via functional NFATc1 responsive element in rank gene promoter.	TNFRSF11A NFATC1	2.26e-05	2	166	2	34358968
Pubmed	[Expression and clinical significances of hedgehog signaling pathway in non-Hodgkin's lymphoma].	GLI1 GLI2	2.26e-05	2	166	2	22040957
Pubmed	Regulation of the murine Nfatc1 gene by NFATc2.	NFATC1 NFATC2	2.26e-05	2	166	2	11786533
Pubmed	PIEZO1 Promotes Odontoblast-Mediated Reactionary Dentinogenesis via SEMA3A.	PIEZO1 SEMA3A	2.26e-05	2	166	2	38910430
Pubmed	NFATc1 and NFATc2 together control both T and B cell activation and differentiation.	NFATC1 NFATC2	2.26e-05	2	166	2	11163226
Pubmed	An enhanced immune response in mice lacking the transcription factor NFAT1.	NFATC1 NFATC2	2.26e-05	2	166	2	8629027
Pubmed	Host control of HIV-1 parasitism in T cells by the nuclear factor of activated T cells.	NFATC1 NFATC2	2.26e-05	2	166	2	9845362
Pubmed	The transcription factor NFAT promotes exhaustion of activated CD8⁺ T cells.	NFATC1 NFATC2	2.26e-05	2	166	2	25680272
Pubmed	The oncogenic GLI transcription factors facilitate keratinocyte survival and transformation upon exposure to genotoxic agents.	GLI1 GLI2	2.26e-05	2	166	2	23792444
Pubmed	Activin-β(c) reduces reproductive tumour progression and abolishes cancer-associated cachexia in inhibin-deficient mice.	INHA INHBC	2.26e-05	2	166	2	23180294
Pubmed	Selective NFAT targeting in T cells ameliorates GvHD while maintaining antitumor activity.	NFATC1 NFATC2	2.26e-05	2	166	2	25583478
Pubmed	Interaction of E2F3a and CASP8AP2 Regulates Histone Expression and Chemosensitivity of Leukemic Cells.	CASP8AP2 E2F3	2.26e-05	2	166	2	36162009
Pubmed	NFATc1 and NFATc2 repress spontaneous osteoarthritis.	NFATC1 NFATC2	2.26e-05	2	166	2	24248346
Pubmed	Genetic deficiency of the transcription factor NFAT1 confers protection against fibrogenic responses independent of immune influx.	NFATC1 NFATC2	2.26e-05	2	166	2	37933452
Pubmed	Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells.	GLI1 GLI2	2.26e-05	2	166	2	24418624
Pubmed	RANK Deficiency Ameliorates Podocyte Injury by Suppressing Calcium/Calcineurin/ NFATc1 Signaling.	TNFRSF11A NFATC1	2.26e-05	2	166	2	30036881
Pubmed	Cloning and chromosomal localization of the human and murine genes for the T-cell transcription factors NFATc and NFATp.	NFATC1 NFATC2	2.26e-05	2	166	2	7842733
Pubmed	NF-AT components define a family of transcription factors targeted in T-cell activation.	NFATC1 NFATC2	2.26e-05	2	166	2	8202141
Pubmed	A genetic association study of CSMD1 and CSMD2 with cognitive function.	CSMD2 CSMD1	2.26e-05	2	166	2	27890662
Pubmed	Retinoic acid-induced CCR9 expression requires transient TCR stimulation and cooperativity between NFATc2 and the retinoic acid receptor/retinoid X receptor complex.	NFATC1 NFATC2	2.26e-05	2	166	2	21148038
Pubmed	Deficiency of the tensin2 gene in the ICGN mouse: an animal model for congenital nephrotic syndrome.	TNS2 ITGA5	2.26e-05	2	166	2	16688531
Pubmed	The complement control-related genes CSMD1 and CSMD2 associate to schizophrenia.	CSMD2 CSMD1	2.26e-05	2	166	2	21439553
Pubmed	Overlapping and distinct transcriptional regulator properties of the GLI1 and GLI2 oncogenes.	GLI1 GLI2	2.26e-05	2	166	2	16434164
Pubmed	Cutting Edge: NFAT Transcription Factors Promote the Generation of Follicular Helper T Cells in Response to Acute Viral Infection.	NFATC1 NFATC2	2.26e-05	2	166	2	26851216
Pubmed	Dual roles for NFAT transcription factor genes as oncogenes and tumor suppressors.	NFATC1 NFATC2	2.26e-05	2	166	2	18809576
Pubmed	The Tax oncogene enhances ELL incorporation into p300 and P-TEFb containing protein complexes to activate transcription.	EP300 ELL	2.26e-05	2	166	2	26188510
Pubmed	Neuropilin-2 acts as a modulator of Sema3A-dependent glioma cell migration.	NRP2 SEMA3A	2.26e-05	2	166	2	19855168
Pubmed	Reciprocal NFAT1 and NFAT2 nuclear localization in CD8+ anergic T cells is regulated by suboptimal calcium signaling.	NFATC1 NFATC2	2.26e-05	2	166	2	17785810
Pubmed	Transcriptional factors p300 and MRTF-A synergistically enhance the expression of migration-related genes in MCF-7 breast cancer cells.	EP300 MRTFA	2.26e-05	2	166	2	26476216
Pubmed	Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells).	NFATC1 NFATC2	2.26e-05	2	166	2	20631193
Pubmed	Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels.	ITGA9 NRP2 NFATC1	2.28e-05	12	166	3	33934370
Pubmed	The Gli3 hypomorphic mutation Pdn causes selective impairment in the growth, patterning, and axon guidance capability of the lateral ganglionic eminence.	SOX5 RELN NRP2 GLI1	2.33e-05	35	166	4	20943929
Pubmed	Semaphorin3A, Neuropilin-1, and PlexinA1 are required for lymphatic valve formation.	ITGA9 NRP2 SEMA3A	2.95e-05	13	166	3	22723296
Pubmed	A role for smoothened during murine lens and cornea development.	NRP2 GLI1 GLI2	4.66e-05	15	166	3	25268479
Pubmed	Gene expression in the developing mouse retina by EST sequencing and microarray analysis.	CASP8AP2 E2F3 DUSP15 FAM156A NHS AFF1	6.47e-05	142	166	6	11812828
Pubmed	Direct repression of anoctamin 1 (ANO1) gene transcription by Gli proteins.	GLI1 GLI2	6.77e-05	3	166	2	30802137
Pubmed	Identification of two new members of the CSMD gene family.	CSMD2 CSMD1	6.77e-05	3	166	2	12906867
Pubmed	Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.	GLI1 GLI2	6.77e-05	3	166	2	26010061
Pubmed	GLI-mediated Keratin 17 expression promotes tumor cell growth through the anti-apoptotic function in oral squamous cell carcinomas.	GLI1 GLI2	6.77e-05	3	166	2	28342001
Pubmed	NFAT transcription factors are essential and redundant actors for leukemia initiating potential in T-cell acute lymphoblastic leukemia.	NFATC1 NFATC2	6.77e-05	3	166	2	34234374
Pubmed	Identification of evidence suggestive of an association with peripheral arterial disease at the OSBPL10 locus by genome-wide investigation in the Japanese population.	OSBPL10 CSMD1	6.77e-05	3	166	2	20610895
Pubmed	The role of GLI-SOX2 signaling axis for gemcitabine resistance in pancreatic cancer.	GLI1 GLI2	6.77e-05	3	166	2	30382189
Pubmed	Selective activation of NFAT by promyelocytic leukemia protein.	NFATC1 NFATC2	6.77e-05	3	166	2	18246125
Pubmed	Semaphorin3A elevates vascular permeability and contributes to cerebral ischemia-induced brain damage.	SEMA3A MICAL2	6.77e-05	3	166	2	25601765
Pubmed	Effect of Rab23 on the proliferation and apoptosis in breast cancer.	GLI1 GLI2	6.77e-05	3	166	2	26238143
Pubmed	20-αHydroxycholesterol, an oxysterol in human breast milk, reverses mouse neonatal white matter injury through Gli-dependent oligodendrogenesis.	GLI1 GLI2	6.77e-05	3	166	2	37541211
Pubmed	Autoamplification of NFATc1 expression determines its essential role in bone homeostasis.	NFATC1 NFATC2	6.77e-05	3	166	2	16275763
Pubmed	Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis.	GLI1 GLI2	6.77e-05	3	166	2	26193634
Pubmed	A critical role of integrin-linked kinase, ch-TOG and TACC3 in centrosome clustering in cancer cells.	ILK TACC3	6.77e-05	3	166	2	20838383
Pubmed	The mechanism of epithelial-mesenchymal transition induced by TGF-β1 in neuroblastoma cells.	GLI1 GLI2	6.77e-05	3	166	2	28393230
Pubmed	The ubiquitin ligase Phr1 regulates axon outgrowth through modulation of microtubule dynamics.	MYCBP2 MAP3K12	6.77e-05	3	166	2	18031680
Pubmed	Role of TCR-induced extracellular signal-regulated kinase activation in the regulation of early IL-4 expression in naive CD4+ T cells.	NFATC1 NFATC2	6.77e-05	3	166	2	12594266
Pubmed	Histone acetyltransferase p300 promotes MRTF-A-mediates transactivation of VE-cadherin gene in human umbilical vein endothelial cells.	EP300 MRTFA	6.77e-05	3	166	2	25746323
Pubmed	Age-dependent effects of secreted Semaphorins 3A, 3F, and 3E on developing hippocampal axons: in vitro effects and phenotype of Semaphorin 3A (-/-) mice.	NRP2 SEMA3A	6.77e-05	3	166	2	11461151
Pubmed	Cloning and characterization of mouse E2F8, a novel mammalian E2F family member capable of blocking cellular proliferation.	E2F3 E2F8	6.77e-05	3	166	2	15722552
Pubmed	Histone acetyltransferase p300 promotes MKL1-mediated transactivation of catechol-O-methyltransferase gene.	EP300 MRTFA	6.77e-05	3	166	2	24096006
Pubmed	NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells.	NFATC1 NFATC2	6.77e-05	3	166	2	19900447
Pubmed	Defective Th1 cytokine gene transcription in CD4+ and CD8+ T cells from Wiskott-Aldrich syndrome patients.	NFATC1 NFATC2	6.77e-05	3	166	2	17082665
Pubmed	Specific and redundant roles for NFAT transcription factors in the expression of mast cell-derived cytokines.	NFATC1 NFATC2	6.77e-05	3	166	2	17082579
Pubmed	NFATc1 controls the cytotoxicity of CD8+ T cells.	NFATC1 NFATC2	6.77e-05	3	166	2	28894104
Pubmed	An innate cell-mediated, murine ulcerative colitis-like syndrome in the absence of nuclear factor of activated T cells.	NFATC1 NFATC2	6.77e-05	3	166	2	15057750
Pubmed	Expression and function of the nuclear factor of activated T cells in colon carcinoma cells: involvement in the regulation of cyclooxygenase-2.	NFATC1 NFATC2	6.77e-05	3	166	2	15632146
Pubmed	Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci.	GLI1 GLI2	6.77e-05	3	166	2	24217340
Pubmed	Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.	TNFRSF11A NFATC1	6.77e-05	3	166	2	20881962
Pubmed	Rapid and Efficient Gene Editing for Direct Transplantation of Naive Murine Cas9+ T Cells.	NFATC1 NFATC2	6.77e-05	3	166	2	34367143
Interaction	TOP3B interactions	VWA5B2 MYCBP2 PHF12 PIEZO1 SAMD4B MTMR8 LAMC3 MIB2 ITGA5 ZNF236 NPHP4 PRAG1 ARHGEF10L STAU1 KMT2C CELSR1 INTS5 PSME4 RPAP1 MEGF8 NFATC1 GLI1 NEK8 PAXIP1 LRRC56 NLRC5 FLCN BAMBI PCNX1 DISP2 TNKS1BP1 ULK2 EP300 ELL PRRC2B ZNF687	1.28e-09	1470	162	36	int:TOP3B
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	DTNB MIB2 EP300	1.15e-04	18	97	3	91
GeneFamily	Nuclear factors of activated T-cells	NFATC1 NFATC2	2.82e-04	5	97	2	665
GeneFamily	E2F transcription factors	E2F3 E2F8	7.81e-04	8	97	2	982
GeneFamily	AF4/FMR2 family\|Super elongation complex	AFF1 ELL	1.00e-03	9	97	2	1280
GeneFamily	Non-clustered protocadherins	PCDH19 PCDH18	1.82e-03	12	97	2	21
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR8 MTMR7	2.86e-03	15	97	2	903
GeneFamily	CD molecules\|Integrin alpha subunits	ITGA5 ITGA9	4.12e-03	18	97	2	1160
GeneFamily	Aminoacyl tRNA synthetases, Class I	MARS1 IARS2	4.59e-03	19	97	2	131
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PSD3 OSBPL10 FGD1 PLEKHA7 PHLDB2	5.05e-03	206	97	5	682
Coexpression	WIERENGA_STAT5A_TARGETS_DN	ILK ACRBP SERPINF1 NDUFAF3 PTGIR USP20 DNAAF3 TRIM8 BAMBI CTSG	4.31e-07	193	165	10	M2213
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 MAMLD1 LAMC3 PTGIR NFATC1 NFATC2 MICAL2 GLI2 KIAA1755	5.76e-08	197	166	9	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 MAMLD1 LAMC3 PTGIR NFATC1 NFATC2 MICAL2 GLI2 KIAA1755	5.76e-08	197	166	9	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 FAT4 MAMLD1 LAMC3 PTGIR NFATC1 NFATC2 MICAL2 GLI2	5.76e-08	197	166	9	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	Club-club-2\|World / Class top	MBD3L2 REG3G OAS2 ADAM30 FCGBP CLCA1 GADD45G DMBT1	2.13e-07	166	166	8	56f11efb6b686b3ee2c34a051f626e3d761b5112
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	RELN TNFRSF11A ITGA9 NRP2 SEMA3A PTPRB NFATC1 MICAL2	2.23e-07	167	166	8	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	Control\|World / group, cell type (main and fine annotations)	SOX5 IQCN MICAL2 ROS1 NR3C2 LIMCH1 USP54 DMBT1	2.33e-07	168	166	8	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWA5B2 NOX4 LAMC3 PTGIR PCDH19 NAV3 KIAA1755 PCDH18	2.79e-07	172	166	8	de4961f4037c439d3e0ec706a257b0ec17f4d5be
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGA9 FIGN PTGIR MICAL2 GLI2 NAV3 KIAA1755 PCDH18	3.19e-07	175	166	8	795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN PIEZO1 TNFRSF11A ITGA9 NRP2 SEMA3A NAV3 PHLDB2	3.63e-07	178	166	8	ad3de3e03a401dac64431a541899445262246347
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN PDK4 PIEZO1 ITGA9 NRP2 SEMA3A NAV3 PHLDB2	4.12e-07	181	166	8	e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PIEZO1 TNFRSF11A ITGA9 NRP2 SEMA3A PTPRB MICAL2	4.30e-07	182	166	8	41b070085edba7a58b81c20aa4942d06f745acf8
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PIEZO1 TNFRSF11A ITGA9 NRP2 SEMA3A PTPRB MICAL2	4.30e-07	182	166	8	5e9a67b2de0daa4fdc344b10a857d8a901ad810e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PIEZO1 TNFRSF11A ITGA9 NRP2 SEMA3A PTPRB MICAL2	4.30e-07	182	166	8	b0fe042c71d6ab8c75abd7ba9d2de00b72d01c0c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 RELN FIGN SSPOP PKHD1 NAV3 ROS1 CSMD1	4.67e-07	184	166	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA9 CELSR1 PKHD1 TNKS1BP1 LIMCH1 USP54 PLEKHA7 PHLDB2	4.67e-07	184	166	8	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 RELN FIGN SSPOP PKHD1 NAV3 ROS1 CSMD1	4.67e-07	184	166	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 RELN FIGN SSPOP PKHD1 NAV3 ROS1 CSMD1	4.67e-07	184	166	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN PDK4 PIEZO1 ITGA9 NRP2 SEMA3A NAV3 PHLDB2	5.07e-07	186	166	8	20340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GALNT3 E2F8 PPP1R3A MICAL2 PKHD1 ROS1 NR3C2 CDH16	5.28e-07	187	166	8	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA9 CELSR1 PKHD1 TNKS1BP1 LIMCH1 USP54 PLEKHA7 PHLDB2	5.28e-07	187	166	8	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 MAMLD1 LAMC3 PTGIR NFATC1 NFATC2 MICAL2 GLI2	5.95e-07	190	166	8	1121eb607a984c59fbffe7220837fc178745aa55
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 MAMLD1 LAMC3 PTGIR NFATC1 NFATC2 MICAL2 GLI2	5.95e-07	190	166	8	048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MAMLD1 PSD3 LAMC3 FIGN PTGIR GLI2 PCDH18	6.19e-07	191	166	8	a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 LAMC3 ITGA9 FIGN PTGIR MICAL2 GLI2 PCDH18	6.19e-07	191	166	8	39092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 DTNB PRAG1 PKHD1 ROS1 NR3C2 LIMCH1 USP54	6.19e-07	191	166	8	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 LAMC3 ITGA9 FIGN PTGIR MICAL2 GLI2 PCDH18	6.19e-07	191	166	8	ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 DTNB CELSR1 PKHD1 ROS1 NR3C2 LIMCH1 USP54	6.70e-07	193	166	8	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	RELN ITGA9 PRAG1 NRP2 PTPRB OSBPL10 LIMCH1 ANKS1A	7.53e-07	196	166	8	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RELN TNFRSF11A ITGA9 UBN2 NRP2 SEMA3A CELSR1 MICAL2	7.53e-07	196	166	8	b04ca69b0ed44e09c989b575f747e1e819cd8008
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	RELN TNFRSF11A ITGA9 UBN2 NRP2 SEMA3A CELSR1 MICAL2	7.53e-07	196	166	8	a31e227de2dc077b81881295b012d22fedbd65ed
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FAT4 MAMLD1 LAMC3 PTGIR NFATC1 NFATC2 MICAL2 GLI2	8.12e-07	198	166	8	a860246bcea847249a78fd2e86ed8e04371060db
ToppCell	5'-Adult-Appendix-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN TNS2 ITGA5 NRP2 SEMA3A PTPRB LIMCH1 PHLDB2	8.12e-07	198	166	8	90e85fe7a0ab376a41666dfff6c0e95b7f1c9475
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SERPINF1 NOX4 ITGA5 GLI2 NAV3 KIAA1755 CFAP69 PHLDB2	8.76e-07	200	166	8	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUSP15 TNFRSF11A CBFA2T3 NRP2 CELSR1 UPK2 LIMCH1	2.69e-06	163	166	7	f4fcac0af9967ec34a43c9674aa17b0aa5344cf6
ToppCell	Club-club-12\|World / Class top	SERPINF1 REG3G OAS2 ADAM30 FCGBP CLCA1 DMBT1	2.92e-06	165	166	7	9b7a31cbdcd2f96b8bd08a4cd4141b92bd5e9062
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A ITGA9 NRP2 SEMA3A NFATC1 MICAL2	3.56e-06	170	166	7	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A ITGA9 NRP2 SEMA3A NFATC1 MICAL2	3.56e-06	170	166	7	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A ITGA9 NRP2 SEMA3A NFATC1 MICAL2	3.56e-06	170	166	7	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	5'-Adult-LargeIntestine-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IQCN FCGBP CLCA1 GADD45G NLRC5 BAMBI DISP2	3.70e-06	171	166	7	48125d825ca2d7ef34564250f5b47d2a579e03c9
ToppCell	Club-club-3\|World / Class top	SERPINF1 REG3G ADAM30 FCGBP CLCA1 GADD45G DMBT1	3.84e-06	172	166	7	34fbb82a2ec77dd183cf26b38edeb7e936b707bc
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	RELN TNFRSF11A ITGA9 NRP2 SEMA3A CLCA1 NR3C2	3.84e-06	172	166	7	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	facs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN TNFRSF11A ITGA9 NRP2 SEMA3A CELSR1 NAV3	4.47e-06	176	166	7	057d2759fdc67176c25802b57a78064d8cc93205
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN TNFRSF11A ITGA9 NRP2 SEMA3A CELSR1 NAV3	4.47e-06	176	166	7	b81e5d23b31cefc8d374ef403e21acc390c14a80
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A ITGA9 NRP2 SEMA3A MICAL2 NAV3	4.64e-06	177	166	7	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PIEZO1 CBFA2T3 ITGA9 NRP2 SEMA3A DNAAF3	4.64e-06	177	166	7	227d4f423b00be2e0c5797e2c5275d342e69a0f4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A ITGA9 NRP2 SEMA3A MICAL2 NAV3	4.64e-06	177	166	7	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PIEZO1 CBFA2T3 ITGA9 NRP2 SEMA3A DNAAF3	4.64e-06	177	166	7	66ffa279147961080c104242a08b176e301d80e3
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NOX4 OAS2 ITGA5 ITGA9 PTPRB NFATC2 AFF1	4.64e-06	177	166	7	1921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A ITGA9 NRP2 SEMA3A MICAL2 NAV3	4.64e-06	177	166	7	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	RELN PIEZO1 CBFA2T3 ITGA9 NRP2 SEMA3A DNAAF3	4.64e-06	177	166	7	0cbf54608d2ba0a0500af142f2029fe5e118c3c2
ToppCell	droplet-Bladder-BLADDER-1m-Endothelial-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HDX LAMC3 CBFA2T3 PPP1R3A PTPRB NFATC2 GIMAP6	4.82e-06	178	166	7	6bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDK4 CBFA2T3 FIGN NRP2 PTPRB LIMCH1 PHLDB2	5.37e-06	181	166	7	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SEMA3A CELSR1 CLCA1 PTPRB DISP2 LIMCH1	5.37e-06	181	166	7	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN TNFRSF11A ITGA9 NRP2 SEMA3A CELSR1 NAV3	5.57e-06	182	166	7	2cc434e46985c66fc36de05344a67aa96d90abc9
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN TNFRSF11A ITGA9 NRP2 SEMA3A CELSR1 NAV3	5.57e-06	182	166	7	0cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCell	facs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN TNFRSF11A ITGA9 NRP2 SEMA3A CELSR1 NAV3	5.57e-06	182	166	7	3e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCell	droplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAMLD1 CBFA2T3 FIGN NRP2 PTPRB GIMAP6 PHLDB2	5.78e-06	183	166	7	709a486154b3157427deb3b8886b63ac39ea42dd
ToppCell	droplet-Liver-nan-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAMLD1 CBFA2T3 FIGN NRP2 PTPRB GIMAP6 PHLDB2	5.78e-06	183	166	7	dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAMLD1 FIGN PTGIR MICAL2 GLI2 NAV3 PCDH18	5.99e-06	184	166	7	e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	PSD3 NOX4 PRAG1 NFATC2 MICAL2 OSBPL10 NHS	5.99e-06	184	166	7	d2bf0135eb56bb410997dccea39c5ede88a0617f
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RELN TNFRSF11A ITGA9 NRP2 SEMA3A NAV3 PHLDB2	6.42e-06	186	166	7	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA9 CELSR1 PKHD1 LIMCH1 USP54 PLEKHA7 PHLDB2	6.42e-06	186	166	7	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA9 CELSR1 PKHD1 LIMCH1 USP54 PLEKHA7 PHLDB2	6.42e-06	186	166	7	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GALNT3 E2F8 FCGBP MICAL2 PKHD1 ROS1 NR3C2	6.42e-06	186	166	7	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA9 CELSR1 MICAL2 OSBPL10 ROS1 USP54 PLEKHA7	6.42e-06	186	166	7	e83718fabb057100835d3357df407f283d23fe16
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A CBFA2T3 ITGA9 NRP2 SEMA3A MICAL2	6.65e-06	187	166	7	65d406122dffe18279f14a1ed35ba091730b97be
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A CBFA2T3 ITGA9 NRP2 SEMA3A MICAL2	6.65e-06	187	166	7	4c15c0ed41a55271fc793cb76fee97fa64190369
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RELN TNFRSF11A CBFA2T3 ITGA9 NRP2 SEMA3A MICAL2	6.65e-06	187	166	7	5274f2b302bbf7fed30c480af4f35058d2cf61e0
ToppCell	droplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	6.89e-06	188	166	7	a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCell	droplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	6.89e-06	188	166	7	54550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RELN TNFRSF11A ITGA9 NRP2 SEMA3A PTPRB PHLDB2	6.89e-06	188	166	7	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	SOX5 FAT4 ITGA9 GLI2 NHS TNFRSF19 PCDH18	7.13e-06	189	166	7	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 PDK4 DTNB ARHGEF10L AFF1 NR3C2 LIMCH1	7.13e-06	189	166	7	c9565e962a13a7713056ec3dbb1b67d24f9889c7
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	RELN TNFRSF11A ITGA9 NRP2 SEMA3A PTPRB NFATC1	7.13e-06	189	166	7	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 PRAG1 PKHD1 ROS1 NR3C2 LIMCH1 USP54	7.38e-06	190	166	7	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	7.38e-06	190	166	7	e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	7.38e-06	190	166	7	f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCell	droplet-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	7.38e-06	190	166	7	b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SOX5 PSD3 PTGIR GLI2 KIAA1755 NHS CFAP69	7.38e-06	190	166	7	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	7.64e-06	191	166	7	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN ITGA9 NRP2 SEMA3A CELSR1 CLCA1 NAV3	7.64e-06	191	166	7	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MAMLD1 PSD3 LAMC3 PTGIR GLI2 PCDH18	7.90e-06	192	166	7	9093a9e94a25682d109a7f6edc256a25a61103a0
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	SOX5 CELSR1 MICAL2 ROS1 NR3C2 LIMCH1 USP54	7.90e-06	192	166	7	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 LAMC3 FIGN PTGIR MICAL2 GLI2 NAV3	7.90e-06	192	166	7	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MAMLD1 PSD3 LAMC3 PTGIR GLI2 PCDH18	7.90e-06	192	166	7	9ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	MAMLD1 PSD3 PRAG1 NFATC1 NFATC2 MICAL2 MRTFA	7.90e-06	192	166	7	8b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN TNFRSF11A ITGA9 NRP2 PTPRB MICAL2 GIMAP6	7.90e-06	192	166	7	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 NOX4 LAMC3 PTGIR NFATC2 GLI2 PCDH18	7.90e-06	192	166	7	9333aba0d04203ccccad78d82bf6359922f810a7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SOX5 MICAL2 PKHD1 ROS1 NR3C2 LIMCH1 DMBT1	7.90e-06	192	166	7	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SOX5 MAMLD1 LAMC3 FIGN PTGIR GLI2 PCDH18	8.18e-06	193	166	7	f1199518c3626fd29bfce65070dd21a660671213
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	SOX5 FAT4 NOX4 NAV3 NHS TNFRSF19 LIMCH1	8.18e-06	193	166	7	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^medium_distal_(2)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GALNT3 E2F8 PPP1R3A MICAL2 PKHD1 ROS1 CDH16	8.74e-06	195	166	7	f08e41706680881ebd0afcd08a02f8ac0089f04e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	OAS2 ITGA5 ITGA9 NRP2 PTPRB NAV3 GIMAP6	9.04e-06	196	166	7	023312af38f816a44b407e0daa32590d953caf99
ToppCell	Control-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	RELN TNFRSF11A ITGA9 NRP2 SEMA3A PLEKHA7 PHLDB2	9.04e-06	196	166	7	e0cf617b0f5d9c3c19574f587a3d0ccbf93d8ca4
ToppCell	Transverse-(5)_Dendritic_cell-(53)_Lymphoid_DC\|Transverse / shred on region, Cell_type, and subtype	PDK4 SERPINF1 PSD3 PTGIR NRP2 PLEKHA7 ANKS1A	9.35e-06	197	166	7	15b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCell	Transverse-Dendritic_cell-Lymphoid_DC\|Transverse / Region, Cell class and subclass	PDK4 SERPINF1 PSD3 PTGIR NRP2 PLEKHA7 ANKS1A	9.35e-06	197	166	7	a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ILK PIEZO1 ITGA5 CBFA2T3 NRP2 CLCA1 TNKS1BP1	9.98e-06	199	166	7	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	SOX5 DTNB KMT2C OSBPL10 AFF1 NR3C2 LIMCH1	9.98e-06	199	166	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SOX5 TNS2 LAMC3 CBFA2T3 FIGN PTGIR PCDH18	1.03e-05	200	166	7	0c648941447c738caf62f2d71e296d6cca492c8b
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	DTNB PSD3 FCGBP GLI2 OSBPL10 NHS TNFRSF19	1.03e-05	200	166	7	682960e28542a3d6c119047cd0131941932cfdea
Drug	Diazoxide [364-98-7]; Up 200; 17.4uM; MCF7; HT_HG-U133A	GALNT3 INHA PSD3 RIF1 FGD1 PCNX1 DMBT1 CFAP69 GIMAP6 MRTFA	1.71e-06	198	163	10	2214_UP
Drug	Convolamine hydrochloride [500-56-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SERPINF1 PSD3 TNS2 PTPN21 MAP3K12 USP20 RPAP1 FGD1 ULK2 ELL	1.71e-06	198	163	10	2771_DN
Drug	ethyl levulinate	CLCA1 CPNE1 UPK2 CTSG EP300	6.41e-06	37	163	5	CID000010883
Disease	cortical thickness	VWA5B2 SOX5 RELN MYCBP2 LAMC3 NRP2 STAU1 SEMA3A DNAAF3 CELSR1 GADD45G PKHD1 NAV3 KIAA1755 AFF1 TACC3 PLEKHA7 ULK2 ELL ANKS1A	1.52e-06	1113	154	20	EFO_0004840
Disease	Ciliopathies	NPHP4 DNAAF3 NEK8 PKHD1 LRRC56 CPLANE1	2.51e-05	110	154	6	C4277690
Disease	physical activity	SAMD4B E2F3 PKHD1 GRIN3A CSMD1	1.00e-04	88	154	5	EFO_0003940
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	RELN TRIM65 E2F3 MIB2 IQCN PPP1R3A GADD45G PKHD1 SLC37A4	1.32e-04	364	154	9	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	neuroimaging measurement	VWA5B2 SOX5 RELN PTPN21 NRP2 SEMA3A DNAAF3 CELSR1 GADD45G PKHD1 NAV3 KIAA1755 AFF1 TACC3 PLEKHA7 ANKS1A	1.56e-04	1069	154	16	EFO_0004346
Disease	prostate cancer (is_marker_for)	ILK INHA E2F3 KMT2C FGD1 EP300	1.75e-04	156	154	6	DOID:10283 (is_marker_for)
Disease	body fat percentage	RELN TRIM65 E2F3 MIB2 IQCN PPP1R3A GADD45G PKHD1 SLC37A4 PRRC2B	2.57e-04	488	154	10	EFO_0007800
Disease	Charcot-Marie-Tooth disease (implicated_via_orthology)	MTMR8 MTMR7 FGD1	2.60e-04	24	154	3	DOID:10595 (implicated_via_orthology)
Disease	suberic acid measurement	TCERG1L PSD3	5.59e-04	7	154	2	EFO_0010534
Disease	level of oxylipin in blood plasma	ITGA9 KIAA1755	5.59e-04	7	154	2	OBA_2050338
Disease	hereditary lymphedema (is_implicated_in)	PIEZO1 CELSR1	5.59e-04	7	154	2	DOID:0050580 (is_implicated_in)
Disease	centronuclear myopathy (implicated_via_orthology)	MTMR8 MTMR7	5.59e-04	7	154	2	DOID:14717 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	SOX5 RELN DTNB MAMLD1 PSD3 SEMA3A DNAAF3 GLI2 CSMD1	5.94e-04	447	154	9	EFO_0000694, MONDO_0100096
Disease	pneumococcal meningitis	CELSR1 ROS1	7.42e-04	8	154	2	EFO_1001114
Disease	coronary aneurysm	CSMD2 GRIN3A CSMD1	8.07e-04	35	154	3	EFO_1000881
Disease	aspartate aminotransferase measurement	INHBC PIEZO1 NOX4 ITGA9 PRAG1 STAU1 DHX15 GLB1 GLI1 NLRC5 CPNE1 CSMD1 ELL	9.50e-04	904	154	13	EFO_0004736
Disease	visceral heterotaxy (implicated_via_orthology)	DNAAF3 PSME4 MEGF8	9.51e-04	37	154	3	DOID:0050545 (implicated_via_orthology)
Disease	Nephronophthisis	NPHP4 NEK8	9.51e-04	9	154	2	cv:C0687120
Disease	centronuclear myopathy X-linked (implicated_via_orthology)	MTMR8 MTMR7	9.51e-04	9	154	2	DOID:0111225 (implicated_via_orthology)
Disease	Osteitis Deformans	TNFRSF11A ZNF687	9.51e-04	9	154	2	C0029401
Disease	primary bacterial infectious disease (implicated_via_orthology)	GLI1 GLI2	9.51e-04	9	154	2	DOID:0050338 (implicated_via_orthology)
Disease	response to lamotrigine	GRIN3A CSMD1	9.51e-04	9	154	2	EFO_0007661
Disease	Colorectal Carcinoma	TCERG1L CBFA2T3 ARHGEF10L KMT2C RPAP1 NFATC1 PKHD1 FLCN NR3C2 EP300 PIGO	1.19e-03	702	154	11	C0009402
Disease	PR interval	MYCBP2 ITGA9 FIGN SEMA3A DNAAF3 MICAL2 KIAA1755 AFF1 PHLDB2	1.21e-03	495	154	9	EFO_0004462
Disease	Carcinoma, Transitional Cell	KMT2C TACC3 EP300	1.28e-03	41	154	3	C0007138
Disease	aortic valve stenosis (is_marker_for)	NFATC1 BAMBI	1.44e-03	11	154	2	DOID:1712 (is_marker_for)
Disease	osteoarthritis, knee	SOX5 PIEZO1 PRAG1 TACC3 EP300	1.47e-03	158	154	5	EFO_0004616
Disease	age at diagnosis, osteonecrosis	RELN LAMC3 NAV3	1.58e-03	44	154	3	EFO_0004259, EFO_0004918
Disease	Adenocarcinoma of large intestine	TBCK FLCN ROS1 EP300	1.63e-03	96	154	4	C1319315
Disease	cortical surface area measurement	SOX5 RELN MYCBP2 LAMC3 DNAAF3 CELSR1 GADD45G TRIM8 PKHD1 NAV3 KIAA1755 AFF1 NR3C2 TACC3 PLEKHA7 ANKS1A	1.84e-03	1345	154	16	EFO_0010736
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	PKHD1 CSMD1	2.03e-03	13	154	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	illegal drug consumption	ITGA9 CSMD1	2.03e-03	13	154	2	EFO_0005431
Disease	Nephronophthisis	NPHP4 NEK8	2.03e-03	13	154	2	C0687120
Disease	1-methylurate measurement	PSD3 SEMA3A	2.36e-03	14	154	2	EFO_0021173
Disease	triacylglycerol 52:1 measurement	NFATC1 CSMD1	2.36e-03	14	154	2	EFO_0010413
Disease	brain measurement, neuroimaging measurement	VWA5B2 SOX5 SEMA3A DNAAF3 GADD45G NAV3 KIAA1755 TACC3 ANKS1A	2.48e-03	550	154	9	EFO_0004346, EFO_0004464
Disease	fibrinogen measurement	PTGIR GADD45G NR3C2 GIMAP6	2.60e-03	109	154	4	EFO_0004623
Disease	S-7-hydroxywarfarin measurement	CSMD2 SEMA3A OSBPL10 CSMD1	2.68e-03	110	154	4	EFO_0803329
Disease	response to cisplatin, platinum measurement	SPATA31E1 FIGN CSMD1	2.70e-03	53	154	3	EFO_0010154, GO_0072718
Disease	Heschl's gyrus morphology measurement	DTNB PCNX1 DISP2	2.70e-03	53	154	3	EFO_0005852
Disease	serum selenium measurement	MTMR7 PKHD1 CSMD1	2.70e-03	53	154	3	EFO_0005266
Disease	response to peritoneal dialysis, peritoneal solute transfer rate	NFATC1 GIMAP6	2.72e-03	15	154	2	EFO_0600089, EFO_0600090
Disease	amino acid measurement	FAT4 PSD3 NRP2 PTPRB GLI2 NAV3 TNFRSF19 NR3C2 CSMD1 MRTFA	3.06e-03	678	154	10	EFO_0005134
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	NEK8 PKHD1	3.10e-03	16	154	2	DOID:0110861 (implicated_via_orthology)
Disease	serum gamma-glutamyl transferase measurement	ARMC7 GALNT3 HDX PSD3 ADAM30 ITGA9 GADD45G APRG1 PKHD1 CPNE1 AFF1 CSMD1	3.14e-03	914	154	12	EFO_0004532
Disease	triglycerides to total lipids in medium HDL percentage	INHBC NLRC5 AFF1	3.16e-03	56	154	3	EFO_0022333
Disease	cholesteryl esters to total lipids in medium HDL percentage	INHBC NLRC5 AFF1	3.16e-03	56	154	3	EFO_0022251
Disease	lymphocyte measurement	MANBA PIEZO1 LINC02908 NLRC5	3.35e-03	117	154	4	EFO_0803546
Disease	creatine kinase measurement	CPNE1 ROS1 MRTFA	3.66e-03	59	154	3	EFO_0004534
Disease	cholesteryl esters to total lipids in large HDL percentage	INHBC PSD3 AFF1	3.66e-03	59	154	3	EFO_0022248
Disease	triglycerides to total lipids in large HDL percentage	INHBC NLRC5 AFF1	3.84e-03	60	154	3	EFO_0022330
Disease	cholesterol to total lipids in medium HDL percentage	INHBC NLRC5 AFF1	3.84e-03	60	154	3	EFO_0022237
Disease	bone density	GALNT3 PSD3 TNFRSF11A TNFRSF19 DMBT1 CTPS1 ANKS1A	4.39e-03	388	154	7	EFO_0003923
Disease	triacylglycerol 46:1 measurement	NFATC1 CSMD1	4.83e-03	20	154	2	EFO_0010401
Disease	hair colour measurement	SOX5 PIEZO1 NOX4 CBFA2T3 ARL17A NFATC1 PKHD1 PCNX1 ELL	5.14e-03	615	154	9	EFO_0007822

Protein segments in the cluster

Peptide	Gene	Start	Entry
GCTQPSTLGQGVHSP	nan	6	Q6ZRP5
GSQGSHIHCPQLPQP	EP300	811	Q09472
SLQLGALVHSPVNCP	ARHGEF10L	796	Q9HCE6
FQGSQGHISIPQPDC	ELL	56	P55199
PHPPSTCGSSALQGQ	CCDC116	46	Q8IYX3
NPELCGSLHLNGSPS	ANKRD10	341	Q9NXR5
AISCGHPGVPANAVL	CSMD1	2856	Q96PZ7
CTFQLHGPNGTVESP	CSMD2	26	Q7Z408
SHTCGNPGRLPNGIQ	CSMD2	136	Q7Z408
TTLNQGSCLHNPPRL	ADAM21	386	Q9UKJ8
NHGLVPDGAVCSNLP	ACRBP	81	Q8NEB7
AGSPAGHVCVLSQGP	FAT4	4481	Q6V0I7
SGTANQPSIAPHRCL	APRG1	96	Q8IVJ8
CAGSGGQLDSILPHQ	ARL17A	131	Q8IVW1
PFQLLCTAGQSHPDG	ANKS1A	516	Q92625
PGGCAAAQHSALAAP	CELSR1	136	Q9NYQ6
AGHTSLPQCINPFTN	DHX15	106	O43143
PGSNCDNSELPGTLH	CASP8AP2	1816	Q9UKL3
HSGALVPSCLGPGQN	DISP2	376	A7MBM2
GNGHPVACVAATQPV	PHYKPL	281	Q8IUZ5
SSALHPLLCVGPEGQ	AIRE	411	O43918
SNHACQRLGGLSAPP	IQCN	781	Q9H0B3
HFQNPTTNCGPPLGT	PCDH18	1061	Q9HCL0
TTNCGPPLGTHSSVQ	PCDH18	1066	Q9HCL0
GNPSHIGSIDPNCDV	PDK4	186	Q16654
GLPGSNASLCLQAAP	OVOS1	506	Q6IE37
PGGKPCSQHIISVTG	PAXIP1	701	Q6ZW49
GNGCEAISPVTSPLH	PCDH19	1056	Q8TAB3
PTLICSPTHGGLGSQ	NFATC2	691	Q13469
QGHGLTPIAPSALTN	FIGN	296	Q5HY92
INRSPGAGPTVVHCS	PTPRB	1891	P23467
QLPTPLLGHSVCTAG	KLHL34	351	Q8N239
CQSHRPNLSGIPGES	FAM156A	131	Q8NDB6
PGLIPGQSTVNHSLG	KMT2C	2991	Q8NEZ4
TGPALHNLCGQKPTI	HDX	236	Q7Z353
GNGHRPSTLSCVNTP	NR3C2	146	P08235
HSPITQGTPLTCSPN	NR3C2	226	P08235
CTEVLHAPLPQGDGN	FLCN	21	Q8NFG4
LGCSPANGNSTVPSL	NUDT4B	146	A0A024RBG1
SVGPGACSQHPGTLD	GPR179	1766	Q6PRD1
QTQGTLHLPTTPCNF	MTMR7	481	Q9Y216
CSQLGNILSQHLGSP	MTMR8	551	Q96EF0
PLHNCLVASENGIAP	KIAA1755	161	Q5JYT7
PLGPEAQAACSQGHL	INHBC	181	P55103
GRNTESPAAIHPCGN	LMOD2	181	Q6P5Q4
CSNPAPLSSPLNGVH	GLB1	426	P16278
PSGHNDSPQLSTCGP	FAM90A27P	181	A6NNH2
LQPCSSQGEGSSPLH	MBD3L5	96	A6NJ08
EPSGQSGLACVQHGL	PCNX1	2176	Q96RV3
QGHLPSSGLCSIPNP	MINDY4B	71	A8MYZ0
HTALPIPNLGTTGSQ	NAV3	21	Q8IVL0
LQPCSSQGEGSSPLH	MBD3L2B	96	A0A1B0GVZ6
PAPCHNLQTSTPGII	NFATC1	66	O95644
LGKHCGNIAPPTIIS	NRP2	101	O60462
PHAPNGACLGSALVT	MEGF8	2791	Q7Z7M0
GLGTRESHSCPQQVP	NEK8	476	Q86SG6
SPGCQGPSVATLHKA	LMLN2	681	A0A1B0GTW7
STHLGSGIPCAQPFN	MMAA	31	Q8IVH4
SGIPCAQPFNSLGLH	MMAA	36	Q8IVH4
STGLAPCLNAHPSEG	GLI1	826	P08151
PASPLALTQGQVSGH	GLI2	386	P10070
HAGGVPLIINCLSSP	ARMC7	96	Q9H6L4
STQHLPPACGARQLS	CBFA2T3	161	O75081
QTPGSCGARIHPIVN	OAS2	686	P29728
PGPVLTLFSHLCNGT	NLRC5	321	Q86WI3
LQPCSSQGEGSSPLH	MBD3L3	96	A6NE82
TLPLQGGIQPNPSHC	NPHP4	406	O75161
QTNLDTHPPGCISLN	NOX4	216	Q9NPH5
INLGCGTHQPGNSVS	RELN	576	P78509
AGVPSSSSHPQPCQI	GRIN3A	26	Q8TCU5
NPPLLVHCSAGVGRT	PTPN21	1101	Q16825
HGNGTVQIPCPSSDQ	PPP1R3A	446	Q16821
LPGSINITAPQCHDG	ITGA9	471	Q13797
GLNCTTNHPINPKGL	ITGA5	866	P08648
SAPPNLCGTSHAIVG	SLC37A4	356	O43826
HISSGATCLNNIPGL	ADAM30	381	Q9UKF2
TTPHGPSSRAGLLQQ	E2F3	101	O00716
HQSVTPPQGLSPTVC	E2F8	531	A0AVK6
EGLTQPLQGGTPHCE	DNAAF3	491	Q8N9W5
LDPQNSNSPLTHGCL	BAMBI	56	Q13145
PHCHEGTIPSGQNST	CPLANE1	2136	Q9H799
LLPSGQHGCQPVSTA	FCGBP	2056	Q9Y6R7
GLLPSGQHGCQPVST	FCGBP	3256	Q9Y6R7
CGLLPSGQHGCQPVS	FCGBP	4456	Q9Y6R7
GGPISLFTQPRCHSA	LINC02908	21	Q6ZV77
LSANGEHPSLVSCNP	GALNT3	606	Q14435
AGAPGDLHCILISNP	GADD45G	111	O95257
PTEHPSTCGQGTLLQ	GGT6	456	Q6P531
SSTPGNPDGITHLQC	DUSP15	266	Q9H1R2
SHPNVLPVLGACQSP	ILK	246	Q13418
TPTHCPQDSLSGVGG	DTNB	556	O60941
PGAVPGCVHSALFQQ	MANBA	41	O00462
GVGSNSLHLPVPSSC	MAP3K12	321	Q12852
GPGAHPSTACAELQV	MAMLD1	96	Q13495
LTPQGGHSCQGLELA	INHA	11	P05111
SRSGHCAALLQTPGP	KLHDC9	186	Q8NEP7
SGGPLLCNNVAHGIV	CTSG	201	P08311
LHALACLQGPGVAPV	DALRD3	61	Q5D0E6
GITGSSCPQRTLHVP	CCDC168	5576	Q8NDH2
SGICTHLNDPDPSGQ	CFAP69	241	A5D8W1
AGVICSGNHLSTPAP	DMBT1	1981	Q9UGM3
CTPRQDHGLIVSGPS	CDH16	676	O75309
VQHFCGGNPSTPIQV	CPNE1	196	Q99829
LDTEAGAPHCGTNPQ	LIMCH1	921	Q9UPQ0
LQPCSSQGEGSSPLH	MBD3L4	96	A6NDZ8
CQPAEAPLGDIGSNH	MICAL2	1376	O94851
NPSTILNPGHCGSLS	REG3G	136	Q6UW15
LQPCSSQGEGSSPLH	MBD3L2	96	Q8NHZ7
GTPNTVTNLHVGAAP	MIB2	811	Q96AX9
IPHSIPLEQGSSCNG	FAN1	351	Q9Y2M0
PGPCLSQQLHSASAE	TACC3	456	Q9Y6A5
PLCTGQHIPACSTQQ	RNF38	211	Q9H0F5
LGQLSQDGLCVPPAH	SSPOP	3571	A2VEC9
GQLLHNGTCVPPTAC	SSPOP	4861	A2VEC9
AICQAIVLSAPGPHA	GIMAP6	111	Q6P9H5
SLTHGAGQVLCGNPT	LRRC56	321	Q8IYG6
PSPVVTSGGNVTLHC	LILRA1	131	O75019
SPSAQDHQPTLGLAC	NHS	551	Q6T4R5
SPQGNSCHVATSPGL	RIF1	376	Q5UIP0
VPAGTHTPGSRLQCT	SCRN2	46	Q96FV2
GVPGSSPACSQHTPQ	FGD1	791	P98174
VQPSPGSVGTHQLAS	PHF12	766	Q96QT6
QFRHGSPTAPICLGS	PLEKHA7	531	Q6IQ23
CNIHVSLVPQPSSTG	CTPS1	176	P17812
GRNAIHQEQSCGPPS	SPATA31E1	631	Q6ZUB1
TGPSGHNIRSCPNLR	MYCBP2	2596	O75592
SGNHTVLQCVVPSLP	PKHD1	1696	P08F94
TSHGHICAPGAPAQQ	PKHD1	3976	P08F94
GVDLENGTCSHPLIP	IARS2	356	Q9NSE4
LICSVPGPNGIDTHF	SEMA3A	291	Q14563
LHGPPGVASACQLLT	INTS5	661	Q6P9B9
HLPLGQSNSCGSVLP	PHLDB2	926	Q86SQ0
FSSCQLSQQPLGPAH	MRTFA	581	Q969V6
LLPHGTPNSASPCSQ	OSBPL10	191	Q9BXB5
SPCSQRHLSVGAPGV	OSBPL10	201	Q9BXB5
IHTPASGPLSVGNIS	AFF1	116	P51825
SAPCPNIHINSTIPG	CLCA1	881	A8K7I4
PIPGGCHNSLKVTSS	TCERG1L	221	Q5VWI1
HPGTGAPLCLSQQLR	TAS1R3	16	Q7RTX0
NGSQGSHPLVSRTVP	UBN2	991	Q6ZU65
GALLGHSSCQNPASP	SERPINF1	11	P36955
NGNRVLGPCALLPHS	NDUFAF3	71	Q9BU61
INCSSQPPLISHGIG	STAU1	521	O95793
IGSNANTGLPCQIHP	SAMD4B	216	Q5PRF9
PLTAAIQHISQGSPG	UBA7	176	P41226
CLGPAHGDSQTPLSQ	PTGIR	311	P43119
LPTGQHIPGCSAQQL	RNF44	121	Q7L0R7
SQCPEPGLRHNGSLS	TNKS1BP1	1371	Q9C0C2
GAPGGHTQNLRCSPL	PRRC2B	841	Q5JSZ5
DLGTPHNLSEPCIQG	ROS1	46	P08922
GPVQCKNGLLVSSPH	SNHG28	101	P0DPA3
QLPGSSHSFQGPNLV	RPAP1	196	Q9BWH6
ASALPHDVCGSNGLP	TBCK	16	Q8TEA7
HDVCGSNGLPLTPNS	TBCK	21	Q8TEA7
LLLVHCTLQAGPGPA	PRAG1	1151	Q86YV5
IVHNCLIGSGNLLPP	PSME4	816	Q14997
PGPITNQTFLCSHGG	USP20	726	Q9Y2K6
FLVCGGQCQPTVSPH	ULK2	381	Q8IYT8
VALPPCHLTGGNATL	UPK2	46	O00526
GPTCHQLLQGLSALS	VWA5B2	481	Q8N398
LGSHPGVCPNQLSPN	WFIKKN1	26	Q96NZ8
SAQGPHCLSAVPTPA	ZXDA	136	P98168
SPNPATLGCGVHSAA	TNFRSF19	261	Q9NS68
DLPATSCLLQHQGPQ	ZNF548	161	Q8NEK5
PSGGPHEITLTINNS	ZNF236	1486	Q9UL36
CSPHHPQVLAQQGSG	ZNF687	226	Q8N1G0
TNHSSCQEPPGPGSL	PIGO	36	Q8TEQ8
PQGNLGAAVSPTSIH	SOX5	361	P35711
VGPTNCSSPHALVLN	PIEZO1	291	Q92508
SAGITGVSHRTQPPC	ZNF701	26	Q9NV72
QSGQPLGPCSSTQHL	TRIM8	411	Q9BZR9
LGPCSSTQHLVALPG	TRIM8	416	Q9BZR9
TLTLCHQPGAVFPLG	TRIM65	496	Q6PJ69
QQGVQPLTGCHSGLD	PSD3	91	Q9NYI0
LCTLPAGHQIGTVSP	MARS1	786	P56192
HIAGPGPQQLCISLE	TNS2	341	Q63HR2
TECAPGLGAQHPLQL	TNFRSF11A	131	Q9Y6Q6
LQDGVSIAPHSCTPG	VWA5B1	101	Q5TIE3
HIGTRFLTTPGCNPQ	USP54	1551	Q70EL1
VDPNAVGNCDPLSGH	LAMC3	816	Q9Y6N6