Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxysterol binding

OSBP INSIG1 INSIG2

3.73e-0516833GO:0008142
GeneOntologyMolecularFunctionbenzoate-CoA ligase activity

ACSM2A ACSM2B

5.11e-053832GO:0018858
GeneOntologyMolecularFunctiondecanoate-CoA ligase activity

ACSM2A ACSM2B

1.02e-044832GO:0102391
GeneOntologyMolecularFunctionfatty-acyl-CoA synthase activity

ACSM2A ACSM2B

4.70e-048832GO:0004321
GeneOntologyMolecularFunctionmedium-chain fatty acid-CoA ligase activity

ACSM2A ACSM2B

9.16e-0411832GO:0031956
GeneOntologyMolecularFunctionbenzodiazepine receptor activity

GABRG2 GABRA3

9.16e-0411832GO:0008503
GeneOntologyBiologicalProcessSREBP-SCAP complex retention in endoplasmic reticulum

INSIG1 INSIG2

1.56e-052822GO:0036316
GeneOntologyBiologicalProcessnegative regulation of SREBP signaling pathway

INSIG1 INSIG2

4.67e-053822GO:2000639
GeneOntologyCellularComponentSREBP-SCAP-Insig complex

INSIG1 INSIG2

4.55e-053822GO:0032937
GeneOntologyCellularComponentinner acrosomal membrane

TMEM190 TMEM225

2.26e-046822GO:0002079
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

CFAP54 DNAH10 MAP2 SPACA9 WLS DNAH8 HYDIN

2.48e-04317827GO:0032838
GeneOntologyCellularComponentcytoplasmic region

CFAP54 DNAH10 MAP2 SPACA9 WLS DNAH8 HYDIN

5.32e-04360827GO:0099568
GeneOntologyCellularComponentcytosolic small ribosomal subunit

RPS4Y2 RPS4X RPS4Y1

7.82e-0446823GO:0022627
GeneOntologyCellularComponentaxoneme

CFAP54 DNAH10 SPACA9 DNAH8 HYDIN

1.33e-03207825GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP54 DNAH10 SPACA9 DNAH8 HYDIN

1.36e-03208825GO:0097014
GeneOntologyCellularComponentdendrite membrane

GABRG2 WLS GABRA3

1.39e-0356823GO:0032590
HumanPhenoThyrotoxicosis with toxic multinodular goiter

CACNA1S GABRA3

4.38e-053202HP:0011785
HumanPhenoThyrotoxicosis with toxic single thyroid nodule

CACNA1S GABRA3

4.38e-053202HP:0011786
HumanPhenoTransient hypophosphatemia

CACNA1S GABRA3

8.75e-054202HP:0008285
HumanPhenoMildly elevated creatine kinase

CACNA1S NEB YME1L1 GABRA3

9.44e-0564204HP:0008180
HumanPhenoMale infertility

RPS4Y2 DNAAF3 DNAH10 DNAH8 HYDIN SYCE1

1.06e-04209206HP:0003251
HumanPhenoGraves disease

CACNA1S GABRA3

1.45e-045202HP:0100647
HumanPhenoDecreased fertility in males

RPS4Y2 DNAAF3 DNAH10 DNAH8 HYDIN SYCE1

2.08e-04236206HP:0012041
HumanPhenoThyrotoxicosis with diffuse goiter

CACNA1S GABRA3

2.18e-046202HP:0011784
HumanPhenoEpisodic hypokalemia

CACNA1S GABRA3

2.18e-046202HP:0012726
HumanPhenoDecreased urinary potassium

CACNA1S GABRA3

2.18e-046202HP:0012364
HumanPhenoEpisodic flaccid weakness

CACNA1S GABRA3

3.04e-047202HP:0003752
DomainRIBOSOMAL_S4E

RPS4Y2 RPS4X RPS4Y1

8.46e-083833PS00528
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

8.46e-083833IPR032277
DomainRibosomal_S4e_N_CS

RPS4Y2 RPS4X RPS4Y1

8.46e-083833IPR018199
DomainRS4NT

RPS4Y2 RPS4X RPS4Y1

8.46e-083833PF08071
DomainRibosomal_S4e_central_region

RPS4Y2 RPS4X RPS4Y1

8.46e-083833IPR013845
DomainRibosomal_S4e_N

RPS4Y2 RPS4X RPS4Y1

8.46e-083833IPR013843
DomainRibosomal_S4e_central

RPS4Y2 RPS4X RPS4Y1

8.46e-083833PD002667
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

8.46e-083833IPR000876
DomainRibosomal_S4e

RPS4Y2 RPS4X RPS4Y1

8.46e-083833PF00900
Domain40S_S4_C

RPS4Y2 RPS4X RPS4Y1

8.46e-083833PF16121
DomainS4

RPS4Y2 RPS4X RPS4Y1

8.41e-075833PS50889
DomainS4

RPS4Y2 RPS4X RPS4Y1

8.41e-075833SM00363
DomainS4_RNA-bd

RPS4Y2 RPS4X RPS4Y1

1.68e-066833IPR002942
DomainKOW

RPS4Y2 RPS4X RPS4Y1

1.36e-0511833IPR005824
DomainKOW

RPS4Y2 RPS4X RPS4Y1

1.36e-0511833PF00467
DomainINSIG_fam

INSIG1 INSIG2

1.95e-052832IPR025929
DomainINSIG

INSIG1 INSIG2

1.95e-052832PF07281
DomainINSIG-1

INSIG1 INSIG2

1.95e-052832IPR009904
DomainS4

RPS4X RPS4Y1

1.16e-044832PF01479
DomainDHC_N1

DNAH10 DNAH8

5.37e-048832PF08385
Domain-

MOSPD2 HYDIN

5.37e-0488322.60.40.360
DomainDynein_heavy_dom-1

DNAH10 DNAH8

5.37e-048832IPR013594
DomainPapD-like

MOSPD2 HYDIN

6.88e-049832IPR008962
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH8

1.72e-0314832IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH8

1.72e-0314832IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH8

1.72e-0314832IPR013602
DomainDHC_N2

DNAH10 DNAH8

1.72e-0314832PF08393
DomainMT

DNAH10 DNAH8

1.72e-0314832PF12777
DomainAAA_8

DNAH10 DNAH8

1.72e-0314832PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH8

1.72e-0314832IPR011704
DomainAAA_5

DNAH10 DNAH8

1.72e-0314832PF07728
DomainDHC_fam

DNAH10 DNAH8

1.97e-0315832IPR026983
DomainDynein_heavy_dom

DNAH10 DNAH8

1.97e-0315832IPR004273
DomainDynein_heavy

DNAH10 DNAH8

1.97e-0315832PF03028
DomainAMP-bd_C

ACSM2A ACSM2B

2.54e-0317832IPR025110
DomainAMP-binding_C

ACSM2A ACSM2B

2.54e-0317832PF13193
DomainCH

NAV2 ACTN4 UTRN

3.03e-0365833SM00033
DomainCH

NAV2 ACTN4 UTRN

3.74e-0370833PF00307
DomainAAA+_ATPase

DNAH10 NAV2 DNAH8 YME1L1

3.89e-03144834IPR003593
DomainAAA

DNAH10 NAV2 DNAH8 YME1L1

3.89e-03144834SM00382
Domain-

NAV2 ACTN4 UTRN

3.89e-03718331.10.418.10
DomainCH

NAV2 ACTN4 UTRN

4.21e-0373833PS50021
DomainCH-domain

NAV2 ACTN4 UTRN

4.54e-0375833IPR001715
DomainActinin_actin-bd_CS

ACTN4 UTRN

4.65e-0323832IPR001589
DomainGABAA/Glycine_rcpt

GABRG2 GABRA3

4.65e-0323832IPR006028
DomainSpectrin

ACTN4 UTRN

4.65e-0323832PF00435
DomainACTININ_2

ACTN4 UTRN

4.65e-0323832PS00020
DomainACTININ_1

ACTN4 UTRN

4.65e-0323832PS00019
DomainAMP-binding_CS

ACSM2A ACSM2B

5.92e-0326832IPR020845
Pubmed

Inactivation of the Rps4 gene on the mouse X chromosome.

RPS4Y2 RPS4X RPS4Y1

1.41e-0838531783379
Pubmed

Homologous ribosomal protein genes on the human X and Y chromosomes: escape from X inactivation and possible implications for Turner syndrome.

RPS4Y2 RPS4X RPS4Y1

1.41e-0838532124517
Pubmed

Expression level of Rps4 mRNA in 39,X mice and 40,XX mice.

RPS4Y2 RPS4X RPS4Y1

1.41e-0838538187552
Pubmed

Relationship between the monosomy X phenotype and Y-linked ribosomal protein S4 (Rps4) in several species of mammals: a molecular evolutionary analysis of Rps4 homologs.

RPS4Y2 RPS4X RPS4Y1

1.41e-0838538808278
Pubmed

Structure and function of ribosomal protein S4 genes on the human and mouse sex chromosomes.

RPS4Y2 RPS4X RPS4Y1

5.63e-0848538139551
Pubmed

Use of a reverse transcriptase-polymerase chain reaction assay to analyze allele-specific expression in individual hippocampal neurons.

RPS4Y2 RPS4X RPS4Y1

1.40e-0758539562962
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

RPS4Y2 RPS4X RPS4Y1

1.40e-0758537681608
Pubmed

An evaluation of the inactive mouse X chromosome in somatic cell hybrids.

RPS4Y2 RPS4X RPS4Y1

4.90e-0778538460399
Pubmed

Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.

RPS4Y2 RPS4X RPS4Y1

4.90e-0778537928394
Pubmed

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.

RPS4Y2 RPS4X RPS4Y1

7.82e-0788538468051
Pubmed

Cloning and localization of the murine Xpct gene: evidence for complex rearrangements during the evolution of the region around the Xist gene.

RPS4Y2 RPS4X RPS4Y1

1.17e-0698539545634
Pubmed

Rps4 maps near the inactivation center on the mouse X chromosome.

RPS4Y2 RPS4X RPS4Y1

3.96e-06138531740345
Pubmed

XIST and the mapping of the X chromosome inactivation centre.

RPS4Y2 RPS4X RPS4Y1

3.96e-06138531772416
Pubmed

The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.

ACSM2A ACSM2B

5.90e-06285216521160
Pubmed

Hair growth defects in Insig-deficient mice caused by cholesterol precursor accumulation and reversed by simvastatin.

INSIG1 INSIG2

5.90e-06285220090767
Pubmed

Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.

INSIG1 INSIG2

5.90e-06285219638338
Pubmed

Severe facial clefting in Insig-deficient mouse embryos caused by sterol accumulation and reversed by lovastatin.

INSIG1 INSIG2

5.90e-06285216955138
Pubmed

Silibinin attenuates adipogenesis in 3T3-L1 preadipocytes through a potential upregulation of the insig pathway.

INSIG1 INSIG2

5.90e-06285219360322
Pubmed

The INSIG1 gene, not the INSIG2 gene, associated with coronary heart disease: tagSNPs and haplotype-based association study. The Beijing Atherosclerosis Study.

INSIG1 INSIG2

5.90e-06285218989534
Pubmed

Golgi phosphoprotein 3 determines cell binding properties under dynamic flow by controlling Golgi localization of core 2 N-acetylglucosaminyltransferase 1.

GOLPH3 GCNT1

5.90e-06285223027862
Pubmed

Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.

ACSM2A ACSM2B

5.90e-06285219634011
Pubmed

Intramembrane glycine mediates multimerization of Insig-2, a requirement for sterol regulation in Chinese hamster ovary cells.

INSIG1 INSIG2

5.90e-06285219617589
Pubmed

Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.

ACSM2A ACSM2B

5.90e-06285229948332
Pubmed

Gene-gene interactions of the INSIG1 and INSIG2 in metabolic syndrome in schizophrenic patients treated with atypical antipsychotics.

INSIG1 INSIG2

5.90e-06285220877301
Pubmed

Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis.

INSIG1 INSIG2

5.90e-06285212624180
Pubmed

Each actin subunit has three nebulin binding sites: implications for steric blocking.

ACTN4 NEB

5.90e-06285211882289
Pubmed

Functional equivalence of human X- and Y-encoded isoforms of ribosomal protein S4 consistent with a role in Turner syndrome.

RPS4X RPS4Y1

5.90e-0628528358435
Pubmed

Insig proteins mediate feedback inhibition of cholesterol synthesis in the intestine.

INSIG1 INSIG2

5.90e-06285224337570
Pubmed

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.

RPS4Y2 RPS4X RPS4Y1

1.56e-052085316635246
Pubmed

Golgi Phosphoprotein 3 Promotes Wls Recycling and Wnt Secretion in Glioma Progression.

GOLPH3 WLS

1.77e-05385229990993
Pubmed

Competitive oxidation and ubiquitylation on the evolutionarily conserved cysteine confer tissue-specific stabilization of Insig-2.

INSIG1 INSIG2

1.77e-05385231953408
Pubmed

Differential localization of GABAA receptor subunits within the substantia nigra of the human brain: an immunohistochemical study.

GABRG2 GABRA3

1.77e-05385218085588
Pubmed

Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis.

INSIG1 INSIG2

1.77e-05385234298014
Pubmed

Three mutations in sterol-sensing domain of SCAP block interaction with insig and render SREBP cleavage insensitive to sterols.

INSIG1 INSIG2

1.77e-05385212482938
Pubmed

Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction.

RPS4Y2 RPS4Y1

1.77e-05385222708584
Pubmed

GABAA receptor subunits in the human amygdala and hippocampus: Immunohistochemical distribution of 7 subunits.

GABRG2 GABRA3

1.77e-05385229023704
Pubmed

Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation.

INSIG1 INSIG2

1.77e-05385224806461
Pubmed

Proteasomal degradation of ubiquitinated Insig proteins is determined by serine residues flanking ubiquitinated lysines.

INSIG1 INSIG2

1.77e-05385216549805
Pubmed

Cholesterol metabolism plays a crucial role in the regulation of autophagy for cell differentiation of granular convoluted tubules in male mouse submandibular glands.

INSIG1 INSIG2

1.77e-05385231558435
Pubmed

Association study between GABA receptor genes and anxiety spectrum disorders.

GABRG2 GABRA3

3.53e-05485219842164
Pubmed

Interactions among genetic variants from SREBP2 activating-related pathway on risk of coronary heart disease in Chinese Han population.

INSIG1 INSIG2

3.53e-05485219740467
Pubmed

Reconstitution of sterol-regulated endoplasmic reticulum-to-Golgi transport of SREBP-2 in insect cells by co-expression of mammalian SCAP and Insigs.

INSIG1 INSIG2

3.53e-05485212842885
Pubmed

Juxtamembranous aspartic acid in Insig-1 and Insig-2 is required for cholesterol homeostasis.

INSIG1 INSIG2

3.53e-05485216606821
Pubmed

Molecular and functional diversity of GABA-A receptors in the enteric nervous system of the mouse colon.

GABRG2 GABRA3

3.53e-05485225080596
Pubmed

Insig required for sterol-mediated inhibition of Scap/SREBP binding to COPII proteins in vitro.

INSIG1 INSIG2

3.53e-05485215899885
Pubmed

The α1, α2, α3, and γ2 subunits of GABAA receptors show characteristic spatial and temporal expression patterns in rhombencephalic structures during normal human brain development.

GABRG2 GABRA3

3.53e-05485226518133
Pubmed

Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.

ACSM2A ACSM2B

3.53e-05485232830538
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RPS4Y2 GABRG2 KNTC1 SMG1 ZC3H7A C6orf118 RPS4X RPS4Y1 NAV2 ACTN4 NEB KLF4 DNAH8

4.65e-051442851335575683
Pubmed

Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase.

INSIG1 INSIG2

5.87e-05585229374057
Pubmed

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.

INSIG1 INSIG2

5.87e-05585222143767
Pubmed

Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?

INSIG1 INSIG2

5.87e-05585218195716
Pubmed

Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins.

INSIG1 INSIG2

5.87e-05585216100574
Pubmed

Insig-2, a second endoplasmic reticulum protein that binds SCAP and blocks export of sterol regulatory element-binding proteins.

INSIG1 INSIG2

5.87e-05585212242332
Pubmed

Post-translational regulation of lipogenesis via AMPK-dependent phosphorylation of insulin-induced gene.

INSIG1 INSIG2

5.87e-05585230733434
Pubmed

The gene-gene interaction of INSIG-SCAP-SREBP pathway on the risk of obesity in Chinese children.

INSIG1 INSIG2

5.87e-05585225028659
Pubmed

Primary Ciliary Dyskinesia

DNAAF3 DNAH8 HYDIN

6.64e-053285320301301
Pubmed

Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.

RPS4Y2 RPS4X RPS4Y1

8.71e-053585315031101
Pubmed

Gene structure, chromosomal localization, and expression pattern of Capn12, a new member of the calpain large subunit gene family.

CAPN12 ACTN4

8.80e-05685210964513
Pubmed

Modelling extracellular domains of GABA-A receptors: subtypes 1, 2, 3, and 5.

GABRG2 GABRA3

8.80e-05685215033447
Pubmed

Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex.

GABRG2 GABRA3

1.23e-0478527560270
Pubmed

An 8-gene signature, including methylated and down-regulated glutathione peroxidase 3, of gastric cancer.

GPX3 KLF4

1.64e-04885220043075
Pubmed

Scavenger receptor CD36 mediates inhibition of cholesterol synthesis via activation of the PPARγ/PGC-1α pathway and Insig1/2 expression in hepatocytes.

INSIG1 INSIG2

1.64e-04885224371122
Pubmed

GABA influences the development of the ventromedial nucleus of the hypothalamus.

GABRG2 GABRA3

1.64e-04885211745664
Pubmed

A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.

LCTL CORO2A ACTN4

1.86e-044585322114352
Pubmed

Genetic association study of putative functional single nucleotide polymorphisms of genes in folate metabolism and spina bifida.

MAT2B BHMT

2.10e-04985219683694
Pubmed

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

GABRG2 GABRA3

2.62e-041085221789198
Pubmed

Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology.

ACTN4 NEB

2.62e-041085220368620
Pubmed

The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation.

RPS4Y2 RPS4X RPS4Y1

3.19e-045485318495661
Pubmed

γ1 GABAA Receptors in Spinal Nociceptive Circuits.

GABRG2 GABRA3

3.20e-041185239137998
Pubmed

Region and layer-specific expression of GABAA receptor isoforms and KCC2 in developing cortex.

GABRG2 GABRA3

3.20e-041185238894703
Pubmed

Kruppel-like factor 4-dependent Staufen1-mediated mRNA decay regulates cortical neurogenesis.

MAP2 KLF4

3.83e-041285229374155
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK2 SRRT ARHGAP40 PLEKHG6 MAT2B ARHGAP17 ARHGEF11 UTRN YME1L1

4.04e-0491685932203420
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

KNTC1 ZC3H7A MOSPD2 THYN1 MASTL PEX5 ARHGAP17 WLS

4.33e-0473385834672954
Pubmed

Sex differences in structure and expression of the sex chromosome genes CHD1Z and CHD1W in zebra finches.

RPS4X RPS4Y1

4.52e-041385214660691
Pubmed

Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.

CER1 WLS

4.52e-041385219841259
Pubmed

Genomic analysis of synaptotagmin genes.

SYT15 SYT13

4.52e-041385211543631
Pubmed

The biochemical anatomy of cortical inhibitory synapses.

GABRG2 GABRA3

5.27e-041485222768092
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH8

5.27e-04148529373155
Pubmed

Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.

MAT2B BHMT

5.27e-041485230753104
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

RPS4Y2 GABRG2 SRRT MAP2 CORO2A RPS4X RPS4Y1 ACTN4 PFKL ARHGEF11 UTRN

7.20e-041431851137142655
Pubmed

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.

RPS4Y2 RPS4X RPS4Y1 ACTN4

7.50e-0416685427160897
Pubmed

Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.

RPS4Y2 RPS4X RPS4Y1

8.06e-047485329795351
Pubmed

AP-SWATH Reveals Direct Involvement of VCP/p97 in Integrated Stress Response Signaling Through Facilitating CReP/PPP1R15B Degradation.

CHEK2 NEB WLS

8.71e-047685329599191
Pubmed

Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.

GABRG2 GABRA3

8.80e-041885219078961
Pubmed

Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis.

INSIG1 INSIG2

8.80e-041885229899135
Pubmed

Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain.

PLEKHG6 ARHGEF11

8.80e-041885212799088
Pubmed

GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality.

GABRG2 GABRA3

8.80e-041885218985723
Pubmed

Structure of the human 80S ribosome.

RPS4Y2 RPS4X RPS4Y1

1.09e-038285325901680
Pubmed

Porcn-dependent Wnt signaling is not required prior to mouse gastrulation.

CER1 WLS

1.09e-032085223760955
Pubmed

Molecular networks involved in mouse cerebral corticogenesis and spatio-temporal regulation of Sox4 and Sox11 novel antisense transcripts revealed by transcriptome profiling.

RPS4Y2 RPS4X RPS4Y1

1.12e-038385319799774
Pubmed

A male germ-cell-specific ribosome controls male fertility.

RPS4Y2 RPS4X RPS4Y1

1.20e-038585336517592
Pubmed

An atlas of genetic influences on human blood metabolites.

ETFDH ARHGAP17 ACSM2A BHMT

1.24e-0319085424816252
Pubmed

A human MAP kinase interactome.

ZC3H7A NAV2 ARHGAP17 ACTN4 NEB ARHGEF11

1.24e-0348685620936779
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

MAP2 GABRA3

1.32e-032285235245678
Pubmed

RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.

RPS4Y2 RPS4X RPS4Y1 PFKL YME1L1

1.58e-0334485536282215
Pubmed

Neural tube defects by NUAK1 and NUAK2 double mutation.

CER1 MAP2

1.71e-032585222689267
Pubmed

Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.

ACSM2A ACSM2B

1.71e-032585219372376
Pubmed

Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition.

MAP2 KLF4

1.71e-032585217130451
Pubmed

Ribosome-mediated specificity in Hox mRNA translation and vertebrate tissue patterning.

RPS4Y2 RPS4X RPS4Y1

1.71e-039685321529712
Pubmed

Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles.

RPS4Y2 RPS4X RPS4Y1

1.81e-03988539507200
InteractionZNF772 interactions

INSIG1 INSIG2 PEX5

5.16e-069813int:ZNF772
Cytoband16p12.3

SMG1 ACSM2A ACSM2B

3.52e-053485316p12.3
CytobandEnsembl 112 genes in cytogenetic band chr16p12

SMG1 ARHGAP17 ACSM2A ACSM2B

3.04e-04172854chr16p12
Cytoband12q24.31

KNTC1 DNAH10 SPPL3

4.54e-048085312q24.31
GeneFamilyS ribosomal proteins

RPS4Y2 RPS4X RPS4Y1

1.12e-0434503728
GeneFamilyDyneins, axonemal

DNAH10 DNAH8

9.93e-0417502536
GeneFamilySynaptotagmins

SYT15 SYT13

9.93e-0417502765
GeneFamilyGamma-aminobutyric acid type A receptor subunits

GABRG2 GABRA3

1.24e-0319502563
GeneFamilyAcyl-CoA synthetase family

ACSM2A ACSM2B

2.33e-032650240
CoexpressionTABULA_MURIS_SENIS_PANCREAS_PANCREATIC_STELLATE_CELL_AGEING

RPS4Y2 RPS4X RPS4Y1

2.63e-069843MM3821
CoexpressionDESCARTES_FETAL_STOMACH_CILIATED_EPITHELIAL_CELLS

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 CDC20B SPACA9 HYDIN

8.23e-06317848M40298
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 TMEM190 DNAH10 C19orf67 SPACA9 HYDIN

3.59e-081698578bca402e144819cb9a8d431d6bf9429be2fff6d6
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

6.93e-0818685776033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

9.90e-08196857de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.14e-07200857cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.14e-0720085779e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.14e-07200857873def69bf55ccbfc944bc10c5afc06be019c312
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PLEKHG6 GPR39 MEIOSIN TMC3 SYCE1

6.99e-0787855aaca22b97a42a1c4a10c5da708d1462101814386
ToppCellCiliated_cells-B-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 HYDIN SYT13

7.38e-07164856fd30c55d0d75ef8b9396435d836187168095152b
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.27e-06180856bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 TMEM190 DNAH10 SPACA9 HYDIN

1.27e-0618085692fb01b91261b3103454924cde56add337b41844
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DNAAF3 C6orf118 DNAH10 CDC20B SPACA9 HYDIN

1.35e-06182856000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.49e-06185856f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.54e-06186856f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellNS-moderate-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAAF3 CFAP54 C6orf118 DNAH10 SPACA9 HYDIN

1.54e-0618685685787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.58e-06187856e61992de4f98eeea08b43213850769d923f8db48
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

DNAAF3 C6orf118 TMEM190 DNAH10 CDC20B SPACA9

1.63e-061888566833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.63e-06188856803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellMulticiliated|World / shred by cell class for nasal brushing

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.69e-0618985634b110aef839376228c5a403a6b5047a945f472b
ToppCellCiliated|World / shred by cell class for parenchyma

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.69e-06189856711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.74e-061908569ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.74e-06190856833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.74e-061908567031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.74e-06190856a90a38fccdbf75a286b4d258fc54920c02b282f7
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.74e-06190856426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.85e-06192856097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAAF3 C6orf118 TMEM190 DNAH10 WLS HYDIN

1.85e-0619285603acd4a26b986e34eee608747347791122f1aa52
ToppCellmulticiliated|World / shred by cell class for turbinate

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.85e-061928560f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAAF3 C6orf118 TMEM190 DNAH10 WLS HYDIN

1.85e-0619285631c6046589e2fbb0486fd044c5b128099d37872f
ToppCellBronchial_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.90e-061938563e693ac4c92576e3f2c9efdd3f1d96d3d336e260
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.90e-06193856e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

1.90e-06193856aa3acc7571405169efb656d214f3a8cbf988362e
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 TMEM190 DNAH10 SPACA9 HYDIN

1.90e-06193856bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell3'-Distal_airway|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 CYP2J2 HYDIN

1.96e-06194856e9ff4398e880d13894e52c0ba9cf19a7662c248b
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAAF3 CFAP54 C6orf118 DNAH10 SPACA9 HYDIN

1.96e-061948561ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.96e-06194856a46238514bca920c3e3713d23c18ba24a09e2a29
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

1.96e-0619485643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-06195856d8bf15aa7cdbc5f29b58e1e6cff76c257f0ea12e
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-061958562d19148df56e99f66b596af2d7f9d0f10f9a9087
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-061958560e763f36786515698b593e5c93f6a56619c1242d
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 DNAH10 MROH2A CDC20B HYDIN

2.02e-06195856e525b69145059b66417589601f7109af63730f3a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-0619585643f0c257e4bb5c627afbdfc695c1199c672842d3
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPS4X INSIG1 GPX3 NAV2 INSIG2 ACTN4

2.02e-061958565ed995717bd3d35cd66442e6e84fe18fe0f7cf96
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-06195856cd6cfe3ef150a4a4575e04fc8a8213cdceefa1c4
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.02e-061958563486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-06195856e22ca35bea06aa95ff2cc771632969f5e7229ffc
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.02e-06195856e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.02e-06195856e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCell3'-Distal_airway-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 CYP2J2 HYDIN

2.02e-0619585672fa2ba064055e2fee2b2cb8633c8f9a3c4373da
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.08e-06196856a37ba02446eef5d1fab703204583f6550a8ec3e1
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAAF3 CFAP54 C6orf118 DNAH10 SPACA9 HYDIN

2.08e-0619685627b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.08e-06196856a156840330630e518bc85633dded6f2c3ead3b30
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.08e-06196856009e83c7251cf300be78b263634d233a8d972a68
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.08e-0619685689ea4d2086e1c769c5a87f1471a6cd4acabcfe33
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.08e-06196856d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.14e-06197856e453d085182364ca347cbcc9dc995c62c3353016
ToppCellwk_20-22-Epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.14e-06197856468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.14e-06197856d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellwk_20-22-Epithelial-Proximal_epithelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.21e-0619885616c54b884500066ade05a406915f9569ca8abdfc
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAAF3 CFAP54 C6orf118 DNAH10 SPACA9 HYDIN

2.21e-06198856ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Ciliated|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.27e-06199856b974b495cabbcc3934936cec846c0e2442a70ac3
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAAF3 CFAP54 C6orf118 DNAH10 SPACA9 HYDIN

2.27e-0619985615f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell(10)_Ciliated|World / shred by cell type by condition

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.34e-062008561b6a8025bd2746b626040058c122b1be3ab2fa61
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-062008569ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-0620085652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-0620085655c148238d5c80c1faa3428a917ae8075be2c145
ToppCellBiopsy_Other_PF-Epithelial-Differentiating_Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856f7b4581d958afbd68f9045af619aaca0ab463439
ToppCellBiopsy_IPF-Epithelial-Differentiating_Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAAF3 C6orf118 TMEM190 DNAH10 CDC20B HYDIN

2.34e-062008568dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-0620085631d75c26055177d656df1fbb10b764cebd61e122
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856721371698bce8890853fb6b6b01a2c20293b39e9
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-0620085685c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9 HYDIN

2.34e-062008564992dbf0514d674017315dbd20d91dfec0c608e9
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856f1a49bc818054fb0734d3b84725ee6487b034567
ToppCellParenchyma_COVID-19-Epithelial-TX-Ciliated|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-0620085612bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856a521cf837cadf280505ff9d7e641a205af7d6513
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellLung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

DNAAF3 CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.34e-06200856cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCellCiliated_cells-A-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 CFAP54 C6orf118 TMEM190 HYDIN

1.05e-051518559d03ce73af15ef40c592d19b36aff46bebc14c40
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|356C / Donor, Lineage, Cell class and subclass (all cells)

MOSPD2 SPACA9 XKR6 WLS ARHGEF11

1.35e-0515985524f87c666eff10c1844c900ffd7ad49fa9f80481
ToppCellnormal-na-Lymphocytic_NK-NK_bright-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

CAPN12 RPS4Y1 CDC20B CCL8 UTRN

1.57e-05164855b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MROH2A GPX3 ACSM2A BHMT ACSM2B

1.92e-05171855f5014e3c387fe3118944af392abe10d6b9b0abab
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Deuterosomal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

DNAAF3 DNAH10 MROH2A CDC20B SPACA9

1.92e-0517185552aec5f6677fe2f7a36fb5b18117a4cffaeff58f
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAAF3 C6orf118 TMEM190 DNAH10 SPACA9

2.26e-05177855aef050784abbba45c4ab4e8328339c8739c5c453
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 CFAP54 DNAH10 SPACA9 HYDIN

2.26e-051778553cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DNAAF3 CFAP54 DNAH10 SPACA9 HYDIN

2.26e-0517785512a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellCiliated_cells-A-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 C6orf118 TMEM190 DNAH10 HYDIN

2.33e-05178855255473ee6df8a13079fb3bb61038162a40cb4c2c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CACNA1S CFAP54 DNAH10 HYDIN

2.33e-05178855b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell15-Airway-Epithelial-Multiciliated_precursor|Airway / Age, Tissue, Lineage and Cell class

DNAAF3 C6orf118 DNAH10 CDC20B SPACA9

2.33e-05178855d8e0a696bdd6af6422d72af0413f9dbd6bc02afa
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAAF3 CACNA1S CFAP54 DNAH10 HYDIN

2.33e-05178855579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP54 C6orf118 TMEM190 DNAH10 SPACA9

2.39e-051798555e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|368C / Donor, Lineage, Cell class and subclass (all cells)

DNAAF3 C6orf118 TMEM190 DNAH10 HYDIN

2.52e-051818555a4574f1bfd0b4ca78da7effda43420857e17296
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|368C / Donor, Lineage, Cell class and subclass (all cells)

DNAAF3 C6orf118 TMEM190 DNAH10 HYDIN

2.52e-05181855a4e891603645f694687e68e585744ddc1a3c8697
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN12 GPX3 ACSM2A BHMT ACSM2B

2.59e-05182855e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.59e-051828557ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

CFAP54 C6orf118 TMEM190 DNAH10 HYDIN

2.59e-05182855fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN12 GPX3 ACSM2A BHMT ACSM2B

2.59e-051828554a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DNAAF3 C6orf118 TMEM190 DNAH10 HYDIN

2.59e-05182855e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
DiseaseX-21319 measurement

ACSM2A ACSM2B

7.44e-062812EFO_0800807
DiseaseX-11478 measurement

ACSM2A ACSM2B

2.23e-053812EFO_0021242
DiseaseThyrotoxic periodic paralysis

CACNA1S GABRA3

2.23e-053812C0268446
Diseasegalectin-4 measurement

CAPN12 ACTN4

4.45e-054812EFO_0020398
Disease3-hydroxyhexanoate measurement

ACSM2A ACSM2B

7.40e-055812EFO_0800378
Diseaseindoleacetoylcarnitine measurement

ACSM2A ACSM2B

1.11e-046812EFO_0800106
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CAPN12 CACNA1S UTRN

1.33e-0436813DOID:11723 (implicated_via_orthology)
Diseaseinterferon gamma measurement

DNAAF3 INSIG2 KLF4

3.77e-0451813EFO_0008165
Diseasephenylacetate measurement

KLF4 ACSM2B

4.83e-0412812EFO_0021012
DiseaseCongenital myopathy (disorder)

CACNA1S NEB

4.83e-0412812C0270960
Diseaseleptin measurement

DOCK2 ARHGAP40 DNAH8

1.46e-0381813EFO_0005000
DiseaseLow Grade Lymphoma (neoplasm)

CHEK2 BHMT

1.51e-0321812C0079747
DiseaseLymphoma, Intermediate-Grade

CHEK2 BHMT

1.51e-0321812C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

CHEK2 BHMT

1.51e-0321812C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

CHEK2 BHMT

1.51e-0321812C0079757
DiseaseLymphoma, Undifferentiated

CHEK2 BHMT

1.51e-0321812C0024306
DiseaseReticulosarcoma

CHEK2 BHMT

1.51e-0321812C0024302
DiseaseLymphoma, Mixed-Cell

CHEK2 BHMT

1.51e-0321812C0024304
DiseaseLymphoma, Diffuse

CHEK2 BHMT

1.51e-0321812C3714542
DiseaseLymphoma, Non-Hodgkin, Familial

CHEK2 BHMT

1.66e-0322812C4721532
DiseaseLymphoma, Small Noncleaved-Cell

CHEK2 BHMT

1.66e-0322812C0079770

Protein segments in the cluster

PeptideGeneStartEntry
GSERSHWEEMLKNPR

SYT13

401

Q7L8C5
DMHTKPWVRARARKE

BHMT

336

Q93088
KRKRFHRLSLEEMPW

CFAP54

1466

Q96N23
VRDPMRSWIGKEHKK

C2orf69

336

Q8N8R5
MIDKHRKDWNPAETR

CYP2J2

261

P51589
LDHWADMEKAGKRLP

ACSM2A

51

Q08AH3
SDRLFWEPMKVHDIR

GPX3

166

P22352
MKELKRHPLFSDVDW

MASTL

826

Q96GX5
EAWTDGKEAMLKHRD

ACTN4

426

O43707
MIHEGPLTWRISKDK

ARHGEF11

966

O15085
SRFGRFWKKPEREMH

CER1

81

O95813
MEKSPLREEAKKFWH

CER1

121

O95813
LRHPWLQDEDMKRKF

CHEK2

481

O96017
DGTWHRAMPRCKIKD

C1R

361

P00736
NNRWREELSHMKRLP

KLF4

41

O43474
IRRIMAAAKPKHDWT

GPR39

301

O43194
EKRMLDPSIKGTFHW

MAT2B

236

Q9NZL9
DRVKHWITFSDPRAM

LCTL

191

Q6UWM7
KKDTDFEHRMPREQW

PFKL

726

P17858
EEMAKRDAEAHPWLS

PEX5

296

P50542
GPLTELEHWKRMSAK

DNAH8

171

Q96JB1
LGEPHKFKREWASVM

INSIG1

151

O15503
EPDHSKEGKAWRMSV

KNTC1

941

P50748
TWHDERLKFDGPMKI

GABRA3

121

P34903
PRMWVEKHPEKESEA

PARP4

841

Q9UKK3
GEPHKFKREWSSVMR

INSIG2

96

Q9Y5U4
SEPHGLRMEEKWLLK

MEIOSIN

41

C9JSJ3
HEAEESRVMLWKRNP

OSBP

671

P22059
IEKSWRELVPGHKEM

PLEKHG6

141

Q3KR16
MEPWTLKHKGSDFER

ETFDH

481

Q16134
DSEKAKGVKWMRPHE

CAPN12

66

Q6ZSI9
DDRMHTVKWVDVPRN

HYDIN

3746

Q4G0P3
MAPWRKADKERHGVA

DOCK2

1

Q92608
RGVSDWDLRMKLHDR

DNAAF3

206

Q8N9W5
KDGDPMQIELRHREW

CACNA1S

976

Q13698
EEKMPRWAAEHRLEE

CORO2A

446

Q92828
KKADAHWITTPNRML

GABRG2

156

P18507
MAEEREPELYLKWKH

C6orf118

1

Q5T5N4
ADPKERWVRDSMKHL

CCL8

76

P80075
LYKKMRWHLEATPEA

C19orf67

231

A6NJJ6
VLDKWVNDPHRMDRR

GOLPH3

221

Q9H4A6
PHAMDRDWKESVASK

CDC20B

146

Q86Y33
DDTAKTMFRIPWKHA

IRF9

31

Q00978
RMPSHKEERWKKRYE

GCNT1

246

Q02742
EALRDRHWKELMEKT

DNAH10

1341

Q8IVF4
NDRSPLVGKIHWEKM

RNF103

126

O00237
DLMKEWIAHSEKLPR

SPACA9

146

Q96E40
KDHRPRMVWDSQASE

CHID1

326

Q9BWS9
WSMSKRDVLDLVPRH

NUP210L

1216

Q5VU65
KDHPWRRETVKSALM

MROH2A

766

A6NES4
FWKEVPRNKVMEHRL

MOSPD2

426

Q8NHP6
RHKPDLFSWDKVVKM

UTRN

191

P46939
RGRELEHWDEMLSKP

SYT15

391

Q9BQS2
IPWEMRIKKIESHFG

TMC3

121

Q7Z5M5
EKTLPEMRAHQDKWA

ARHGAP17

231

Q68EM7
SRRDWPLHVMKAVLE

SMG1

2271

Q96Q15
EMKWKEDSRPHLFLI

NAV2

2026

Q8IVL1
RVAAPKHWMLDKLTG

RPS4Y1

11

P22090
RVAAPKHWMLDKLTG

RPS4Y2

11

Q8TD47
RVAAPKHWMLDKLTG

RPS4X

11

P62701
DHLRPADAIMQKAWR

ST7

181

Q9NRC1
PQKRMRRDWDEHSSD

SRRT

76

Q9BXP5
LDHWADMEKAGKRLP

ACSM2B

51

Q68CK6
QWKARMEFILRHLPD

CDKN2AIPNL

36

Q96HQ2
RAKAWDVTGPMLLHK

TIGD3

91

Q6B0B8
KIDMPRKRYPAWDAH

XKR6

586

Q5GH73
RPDENVRRKHMWALV

TMEM190

71

Q8WZ59
PENHMEKDSWKTLRT

RASGEF1A

461

Q8N9B8
GLKTWLRRMHADRDK

ARHGAP40

496

Q5TG30
KLVEWTSPGHMEERK

SERPINB13

266

Q9UIV8
DLWDFHMPERLAKEI

SYCE1

171

Q8N0S2
KGDLRRMWSEPFHSK

SPPL3

361

Q8TCT6
DLKRMISNPWERTHF

RNF175

281

Q8N4F7
RELEHWDEMLSKPKE

SYT15B

446

X6R8R1
AKEPDSWHVKDNRVM

SLFN12

316

Q8IYM2
MIDPETRHKAFLKAW

TTTY12

1

Q9BZ98
MADERKDEAKAPHWT

MAP2

1

P11137
MKKSLDTTDNWHIRP

YME1L1

91

Q96TA2
HWLMKSEPESRLEKG

THYN1

56

Q9P016
LISEDERAKMNHSPW

TMEM225

36

Q6GV28
HEWEERRDALKMKLN

ZC3H7A

931

Q8IWR0
LEQEKEPWTRKRHRM

ZNF681

56

Q96N22
AEWTEMAHERVPRKL

WLS

146

Q5T9L3
DKKDVPEEQEHMRRW

AGPAT5

266

Q9NUQ2
AHSDDWRLDIMLKRK

PLD2

376

O14939
REAWDKDKTQIHIMP

NEB

2481

P20929