Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

TIMM23 MPEG1 SLC7A4 SLC25A20 ROMO1 SLC44A1 SLC16A5 SLC18A1 SLC39A11 TIMM23B

1.78e-0511803410GO:0022857
GeneOntologyMolecularFunctiontransporter activity

TIMM23 MPEG1 SLC7A4 SLC25A20 ROMO1 SLC44A1 SLC16A5 SLC18A1 SLC39A11 TIMM23B

3.81e-0512893410GO:0005215
GeneOntologyBiologicalProcessprotein import into mitochondrial matrix

TIMM23 ROMO1 TIMM23B

4.58e-0620343GO:0030150
GeneOntologyBiologicalProcessmitochondrial transmembrane transport

TIMM23 SLC25A20 ROMO1 TIMM23B

2.71e-05106344GO:1990542
GeneOntologyBiologicalProcessprotein transmembrane import into intracellular organelle

TIMM23 ROMO1 TIMM23B

3.88e-0540343GO:0044743
GeneOntologyBiologicalProcessimport into the mitochondrion

TIMM23 ROMO1 TIMM23B

9.58e-0554343GO:0170036
GeneOntologyBiologicalProcessresponse to glycoprotein

TSHR MAN1A2

1.72e-0412342GO:1904587
GeneOntologyBiologicalProcessprotein transmembrane transport

TIMM23 ROMO1 TIMM23B

2.65e-0476343GO:0071806
GeneOntologyBiologicalProcessmitochondrial transport

TIMM23 SLC25A20 ROMO1 TIMM23B

3.48e-04205344GO:0006839
GeneOntologyCellularComponentTIM23 mitochondrial import inner membrane translocase complex

TIMM23 ROMO1 TIMM23B

2.17e-0616343GO:0005744
GeneOntologyCellularComponentmigrasome

TIMM23 TIMM23B

9.18e-059342GO:0140494
GeneOntologyCellularComponentinner mitochondrial membrane protein complex

TIMM23 ROMO1 TIMM23B

9.69e-04120343GO:0098800
DomainMFS

SLC16A5 SLC18A1

7.22e-0377312IPR011701
DomainMFS_1

SLC16A5 SLC18A1

7.22e-0377312PF07690
DomainMFS

SLC16A5 SLC18A1

1.38e-02108312PS50850
DomainMFS_dom

SLC16A5 SLC18A1

2.07e-02134312IPR020846
Pubmed

Genetic and structural characterization of the human mitochondrial inner membrane translocase.

TIMM23 ROMO1 TIMM23B

3.08e-071434310339406
Pubmed

Hormonal regulation of mitochondrial Tim23 gene expression in the mouse mammary gland.

TIMM23 TIMM23B

9.28e-07234211165051
Pubmed

Effect of Tim23 knockdown in vivo on mitochondrial protein import and retrograde signaling to the UPRmt in muscle.

TIMM23 TIMM23B

9.28e-07234229949403
Pubmed

Evi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger protein.

ZNF521 ZNF423

9.28e-07234212393497
Pubmed

Direct transcriptional repression of Zfp423 by Zfp521 mediates a bone morphogenic protein-dependent osteoblast versus adipocyte lineage commitment switch.

ZNF521 ZNF423

2.78e-06334224891617
Pubmed

Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes.

TIMM23 TIMM23B

2.78e-06334212437925
Pubmed

ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies.

ZNF521 ZNF423

2.78e-06334226788497
Pubmed

Mutant huntingtin does not cross the mitochondrial outer membrane.

TIMM23 TIMM23B

2.78e-06334232821928
Pubmed

Development of renal failure in PargParp-1 null and Timm23 hypomorphic mice.

TIMM23 TIMM23B

2.78e-06334231326434
Pubmed

Defective mitochondrial protein import contributes to complex I-induced mitochondrial dysfunction and neurodegeneration in Parkinson's disease.

TIMM23 TIMM23B

2.78e-06334230405116
Pubmed

NOX4-TIM23 interaction regulates NOX4 mitochondrial import and metabolic reprogramming.

TIMM23 TIMM23B

2.78e-06334237044213
Pubmed

Neurological phenotype and reduced lifespan in heterozygous Tim23 knockout mice, the first mouse model of defective mitochondrial import.

TIMM23 TIMM23B

5.56e-06434219111522
Pubmed

The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix.

TIMM23 TIMM23B

5.56e-06434210393182
Pubmed

De novo triiodothyronine formation from thyrocytes activated by thyroid-stimulating hormone.

DIO1 TSHR

9.26e-06534228743746
Pubmed

Early hematopoietic zinc finger protein (EHZF), the human homolog to mouse Evi3, is highly expressed in primitive human hematopoietic cells.

ZNF521 ZNF423

9.26e-06534214630787
Pubmed

Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice.

TIMM23 TIMM23B

1.39e-05634215282315
Pubmed

A mouse model demonstrates a multigenic origin of congenital hypothyroidism.

DIO1 TSHR

1.39e-05634216150900
Pubmed

A spastic paraplegia mouse model reveals REEP1-dependent ER shaping.

TIMM23 TIMM23B

1.39e-05634224051375
Pubmed

Alterations in expression levels of deafness dystonia protein 1 affect mitochondrial morphology.

TIMM23 TIMM23B

1.94e-05734221984432
Pubmed

Role of Bax and Bak in mitochondrial morphogenesis.

TIMM23 TIMM23B

1.94e-05734217035996
Pubmed

Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death.

TIMM23 TIMM23B

2.59e-05834215044455
Pubmed

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.

TIMM23 ROMO1

2.59e-05834230598479
Pubmed

The dynamin-related GTPase Drp1 is required for embryonic and brain development in mice.

TIMM23 TIMM23B

3.33e-05934219752021
Pubmed

Mitocytosis, a migrasome-mediated mitochondrial quality-control process.

TIMM23 TIMM23B

4.15e-051034234048705
Pubmed

Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation.

TIMM23 TIMM23B

7.19e-051334210920231
Pubmed

The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta.

ALDH1A1 SLC18A1

1.10e-041634215584907
Pubmed

Zfp423/OAZ participates in a developmental switch during olfactory neurogenesis.

ZNF521 ZNF423

1.10e-041634217521568
Pubmed

Rapid and Integrative Discovery of Retina Regulatory Molecules.

SLC44A1 APH1A

1.10e-041634230157441
Pubmed

Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification.

TIMM23 TIMM23B

1.25e-041734211709546
Pubmed

HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention.

KAT2B NUP54

1.57e-041934221489275
Pubmed

PDGFRα controls the balance of stromal and adipogenic cells during adipose tissue organogenesis.

ZNF521 ZNF423

1.57e-041934228049691
Pubmed

Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.

ALDH1A1 SLC18A1

1.74e-042034223637192
Pubmed

The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.

DIO1 TSHR

1.74e-042034224265449
Pubmed

Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.

TIMM23 TIMM23B

2.12e-042234211431695
Pubmed

Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells.

KAT2B ALDH1A1

2.32e-042334219737349
Pubmed

Interaction network of human early embryonic transcription factors.

ZNF521 KAT2B ZNF423 NUP54

3.72e-0435134438297188
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

TSHR ALDH1A1 ZNF423

3.94e-0414634329688375
Pubmed

γ-Linolenic acid in maternal milk drives cardiac metabolic maturation.

SLC25A20 MMP9

3.97e-043034237225978
Pubmed

Specification of dopaminergic subsets involves interplay of En1 and Pitx3.

ALDH1A1 SLC18A1

4.24e-043134223863478
Pubmed

Altered expression of genes involved in regulation of vitamin A metabolism, solute transportation, and cytoskeletal function in the androgen-insensitive tfm mouse testis.

SLC7A4 ALDH1A1

4.52e-043234217332066
Pubmed

The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development.

TIMM23 TIMM23B

6.38e-043834233913477
Pubmed

Proteomic analysis of the mouse liver mitochondrial inner membrane.

TIMM23 SLC25A20 TIMM23B

6.68e-0417534312865426
GeneFamilySolute carriers

SLC7A4 SLC25A20 SLC44A1 SLC16A5 SLC18A1 SLC39A11

7.71e-06395236752
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac|lymph-node_spleen / Manually curated celltypes from each tissue

MPEG1 ALDH1A1 MMP9 VMO1

1.55e-05199344c051cc3e42cfa2ec09fd8dae1172af350bb2dfcb
ToppCellcontrol-Epithelial-Secretory-diff|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MPEG1 ALDH1A1 VMO1

2.37e-0573343dded04580ac197d3471a8ed43e1e61c56ee09f78
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

TSHR SLC18A1 NOBOX

3.60e-05843439417fffe0ba79f5851920258dcd0f6c09218be13
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPEG1 VMO1 UNC79

8.49e-051123439801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF521 ALDH1A1 MMP9

1.02e-04119343aa3860c8d25c85baa79a0b6637bce2e269adfcc2
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZFHX2 ALDH1A1 TRO

1.98e-04149343e99b7cd3728ce76b365526734c2e7f845b2e62c8
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-hematopoietic_progenitor|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZFHX2 ALDH1A1 TRO

1.98e-041493436a28dd4530ed411747fdfe743db138a1b5547ed7
ToppCellLPS-IL1RA-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPEG1 ZFHX2 SLC16A5

2.18e-0415434343735f7c58cac51855ded486ee8d8729a1b9909e
ToppCellLPS-IL1RA-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MPEG1 ZFHX2 SLC16A5

2.18e-04154343d55fb73461885e1e02061a344ff89624ef4de487
ToppCellfacs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l8|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MPEG1 MMP9 SLC18A1

2.30e-041573435098675f64342c41c5ca3551b24962d10c83e64d
ToppCell18-Distal-Epithelial-Basal_cell|Distal / Age, Tissue, Lineage and Cell class

SLC7A4 SLC25A20 SLC39A11

2.35e-04158343183f445967e09e871c93d8e94781ed9fec894169
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ALDH1A1 MMP9 SLC18A1

2.53e-0416234308ee7ae56e4927874515c47adc86dd845bf29a26
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 SLC7A4 ZNF423

2.57e-0416334373c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MPEG1 CMAHP VMO1

2.62e-0416434343045879505774ac0d9b7f760557955564f06d00
ToppCelllung-Club_Cells|lung / shred on tissue and cell subclass

ALDH1A1 CMAHP VMO1

2.62e-04164343b12cacd499b18b96120ca6d14646aebeaed41d10
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MPEG1 UNC79 SLC39A11

2.62e-04164343cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MPEG1 UNC79 SLC39A11

2.62e-041643436d331e74efecb4733d87653f86cd67247be05025
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC7A4 SLC18A1 UNC79

2.62e-04164343be49af6335f2505065cde2cb9800e4a5516811b1
ToppCellcritical-Myeloid-Mast_cell|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ZNF521 SLC44A1 TRO

2.67e-0416534334a1cc6ccd46c059354e8fbde1ac69f202695a4e
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF521 SLC44A1 SLC39A11

2.67e-0416534337615622c736e43260c38016e7c9e565ac97a3e8
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 SLC25A20 ALDH1A1

2.67e-04165343ce79d217df88035457cd58f679e72dd98722ae22
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF521 SLC44A1 SLC39A11

2.67e-04165343640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ZNF521 SLC44A1 SLC39A11

2.67e-04165343f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 SLC25A20 ALDH1A1

2.71e-0416634322b31acbbef1936ce19b393cf880c63ea2fa0f1b
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OXCT2 MPEG1 MMP9

2.76e-041673432dc3de562a26077cb76855b725cf278a272d3276
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC16A5 CMAHP SLC39A11

2.76e-041673438ec7a98b542b134f48df8fbec351693cc5cfe55c
ToppCellfacs-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC16A5 CMAHP SLC39A11

2.76e-04167343a9f28c4649ce344ae3ba3a3acb58da9c7efad901
ToppCellNS-critical-d_07-13-Myeloid-Mast_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZNF521 SLC44A1 TRO

2.76e-041673438a14fd980d8ebe8ef0216221f619d31aaa27ff15
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MPEG1 ZFHX2 SMG7

2.81e-0416834327cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

OXCT2 MMP9 VMO1

2.86e-04169343a0681317867e31319210a23e56660a53f4529efe
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A5 CMAHP SLC39A11

2.86e-04169343e348d9877a1bcad4f33dd7b2ce6cb0049583c4d2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF521 ZNF423 NOBOX

2.86e-041693437c994653b0d629dfb046755d6b678452de0a15d2
ToppCellfacs-Lung-EPCAM-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC16A5 CMAHP SLC39A11

2.86e-041693433167ca0c826244280e0e07d1e02656cf5e4e75a5
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

ZNF521 SLC44A1 SLC39A11

2.86e-04169343fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC16A5 SLC18A1 UNC79

2.91e-04170343941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

ZNF521 SLC44A1 SLC39A11

2.91e-04170343c80f6d29096c372da95a8407f402349ff1bb7018
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 SLC25A20 ALDH1A1

2.96e-041713435d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 SLC25A20 ALDH1A1

2.96e-04171343b0d616699e2110ffd6cf1868ed1f1a29f824e1fc
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 SLC25A20 ALDH1A1

2.96e-04171343e7dbee63cc39230aa12e7868ec78a129160c0d22
ToppCell3'_v3-blood-Mast|blood / Manually curated celltypes from each tissue

ZNF521 ALDH1A1 VMO1

3.01e-04172343e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

OXCT2 MMP9 VMO1

3.01e-04172343ac20766d1fd43eab8c3ff5e7418a6b38bebf0bd5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-conventional_dendritic_cell-DC_c2-CD1C|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

OXCT2 MMP9 VMO1

3.01e-041723433fd1bc4a8ced0bf9e26ca4ce6d83b5b97bbc2556
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MPEG1 ALDH1A1 SLC18A1

3.01e-041723430b247fe57163af08132db8df42e6757699885295
ToppCellBL-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

OXCT2 TSHR TIMM23B

3.06e-0417334390700a876d997f7c0f7b3899dffcda7fdafee547
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A1 SLC16A5 CMAHP

3.11e-04174343cdfc50e5383c8670ce5109736aff36406f46c03d
ToppCell3'_v3-blood-Mast-Mast_cell_granulo-myelo|blood / Manually curated celltypes from each tissue

ZNF521 ALDH1A1 VMO1

3.22e-04176343d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

MPEG1 VMO1 ZNF423

3.22e-04176343195393b38f1335f2cb96125616d75c164a6026c2
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC25A20 ALDH1A1 SLC16A5

3.22e-041763437622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

MMP9 VMO1 SLC18A1

3.33e-04178343e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MMP9 APH1A NPM3

3.38e-04179343252328c9ce9bf61f741a4ebe170c93733c8747b6
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ZNF521 ALDH1A1 KRT73

3.38e-04179343810972561d1ae5a68389b54ceeac7a49890513a4
ToppCellBLOOD--(5)_Plasma| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

OXCT2 TSHR SLC44A1

3.44e-041803431ac0a0a715f4a36df0762bb0de44802d6ffa284c
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

MPEG1 VMO1 ZNF423

3.44e-04180343a0b35067b6f2dbd8145da8bab760e9f650f045b0
ToppCellBLOOD--(5)_Plasmablasts| / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

OXCT2 TSHR SLC44A1

3.44e-041803434b9be1b19d4ecd0a3b924e4557a1ecfbcff2d705
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Mesenchymal-skeletal_muscle_satellite_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TIMM23 SLC39A11 NPM3

3.44e-041803436111aefb7b00047a5a265838353dc163036ad95a
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

MMP9 APH1A NPM3

3.50e-041813431168164994d5e2072c80d058e42aab72a0cf9867
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A1 SLC16A5 CMAHP

3.50e-0418134397022416d0f5a5ba9c9bd5e70ce95cf4cb19af89
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ALDH1A1 VMO1 TRO

3.55e-04182343818b5155ec81f0059048d6070a108116ecd72e3c
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DIO1 SLC7A4 TSHR

3.67e-0418434361caaa31975e05c9a6512079c791fed5a9e2d39f
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DIO1 SLC7A4 TSHR

3.67e-0418434303da0f0f89f1ca5a3ccca1e22972f3129464e68e
ToppCellfacs-Trachea-24m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DIO1 SLC7A4 TSHR

3.67e-041843439ed2a65a4ca0ebbbb89ace61027522f93369843d
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MPEG1 REV3L MMP9

3.67e-04184343b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A1 SLC16A5 CMAHP

3.67e-041843431da7936a2616986efd5de601ad525f1f2355128a
ToppCellfacs-Trachea-nan-24m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 ZFHX2 SLC7A4

3.73e-04185343e502ec54971f518d0cf1b619b745607a8ab5ddf3
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-CD1c-positive_myeloid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SLC44A1 MMP9 VMO1

3.79e-041863430dce13e15c3bf32610bf2dad31253b52a39cff87
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC44A1 TRO ZNF423

3.85e-04187343ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell3'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPEG1 MMP9 VMO1

3.97e-04189343b491204cf38dc80a2583e3082a82dda8d77b3fc4
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

ZNF521 ALDH1A1 TRO

3.97e-041893432157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellnormal-na-Lymphocytic_B-B_plasma|normal / PBMC cell types (v2) per disease, treatment status, and sex

OXCT2 TSHR SLC44A1

3.97e-04189343659deb617a560bcde67c75f477d30ce85aaec3c6
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

OXCT2 TSHR SLC44A1

3.97e-0418934359e6fec454de621119571d4a8ec48be3bf02a32e
ToppCellnormal-na-Lymphocytic_B-B_plasma-female|normal / PBMC cell types (v2) per disease, treatment status, and sex

OXCT2 TSHR SLC44A1

3.97e-0418934367f9a9861d2dcc128b7a69432c6b31da185e2249
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Erythrophagocytic_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

MPEG1 MMP9 VMO1

4.03e-0419034396c6078619e85f630c9754aca5d6066433e22836
ToppCellwk_20-22-Hematologic-Myeloid-APOE+_Mac1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MPEG1 MMP9 SLC39A11

4.09e-04191343c204ec71b7755b46a18d3a6aa84d0f407145ce9d
ToppCellfacs-Lung-EPCAM-24m-Epithelial-Neuroendocrine|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A4 SLC18A1 TRO

4.09e-04191343501d4f6ad389d9ac5051d4247b9bd3da96f713f9
ToppCellfacs-Lung-EPCAM-24m-Epithelial-lung_neuroendocrine_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC7A4 SLC18A1 TRO

4.09e-041913438e06cc61eaff1796c2ce014074029408ba88d561
ToppCellfacs-Aorta-Heart-3m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC44A1 ALDH1A1 CMAHP

4.15e-041923430dc1f46e40346ed0b286e53b106a812441575100
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZNF521 ALDH1A1 TRO

4.15e-0419234361677831b096b36f6325e9cb047483dd72aa71c2
ToppCellfacs-Trachea-nan-3m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DIO1 SLC7A4 TSHR

4.22e-041933433038ed3e53d3367136fac5c9773cd5b7414f49d3
ToppCellerythropoietic-CD34+_Pro-erythroblast|World / Lineage and Cell class

ZNF521 ALDH1A1 NPM3

4.28e-04194343cd12d01f6f2f12bbc33ed523bc678d3965074974
ToppCellMonocytes-C1QA+_Monocytes|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

MPEG1 ALDH1A1 VMO1

4.28e-041943433e104e85574894c04791252d466d438fc809dde3
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-HSC-MPP|bone_marrow / Manually curated celltypes from each tissue

ZNF521 ROMO1 NPM3

4.28e-041943433a7e7acbddc63da44d9a04a5b52adf6934fc83dd
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPEG1 MMP9 VMO1

4.35e-04195343028622b234551b185977fbee10c06851a45456a5
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors|bone_marrow / Manually curated celltypes from each tissue

ZNF521 ROMO1 SLC44A1

4.41e-041963434143dab6dce3c88c9b002c64699ab453149990e7
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC7A4 ALDH1A1 SLC39A11

4.48e-041973437619924615a43011b4a86efbe6e7e5445f96722b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MPEG1 MMP9 VMO1

4.48e-04197343dc56bb758c7c5bd151be66f8f3b7078d085f72c7
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MPEG1 MMP9 VMO1

4.48e-041973432efb5acd56b96e5afd8d72b927f1d53cc443766f
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPEG1 MMP9 VMO1

4.48e-04197343e698a0bbb20bd4868ff4348f2ac9f609942b55fa
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_2|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MPEG1 MMP9 SLC18A1

4.54e-041983432e07e62ed230763a6859a8ce19429b5ca8b365a6
ToppCell3'_v3-GI_small-bowel-Mast-Mast_cells|GI_small-bowel / Manually curated celltypes from each tissue

ZNF521 SLC44A1 ALDH1A1

4.54e-04198343920d2e6603a06c2e8dcb6be127202d222c662bca
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_2|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MPEG1 MMP9 SLC18A1

4.54e-041983433b0143efc33486c1e340ca57981c83cf7e2cad29
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPEG1 MMP9 VMO1

4.54e-04198343acb84681569651447d684aa3960f0510d7ff17e8
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_2-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MPEG1 MMP9 SLC18A1

4.54e-04198343f254287e13328a8f3b14bf4e44736041ad35593e
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MPEG1 ALDH1A1 MMP9

4.54e-04198343641e7be258303bb9782d19fcf8693f317581d3b8
ToppCell3'_v3-GI_small-bowel-Mast|GI_small-bowel / Manually curated celltypes from each tissue

ZNF521 SLC44A1 ALDH1A1

4.54e-04198343807e3ed34739eca159dd0970f884b073e588c649
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MPEG1 MMP9 VMO1

4.54e-04198343af682919a874d60f579e854c274dc47063015ea9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ALDH1A1 MMP9 VMO1

4.54e-04198343455d55cfdeb8b6b13c289b53e1a5184a574e2e35
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_MHC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MPEG1 ALDH1A1 VMO1

4.61e-04199343928a3dbef54a2c292a71edb398d64dd54c259164
ToppCellIPF-Myeloid-Macrophage|Myeloid / Disease state, Lineage and Cell class

SLC44A1 MMP9 SLC39A11

4.61e-041993433c2b362d5e824e1a04830e70352f8818de984174
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MPEG1 MMP9 VMO1

4.61e-04199343ca0f6526ba0dcf8789dd3b583291519626427f2f
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KAT2B UNC79 TRO

4.61e-0419934319a97e27a4758e794ce7246d295e112b47931a48
ComputationalBlood cells and cancer expression clusters.

KAT2B REV3L MMP9 SMG7 UNC79 NUP54

1.66e-04407236MODULE_532
ComputationalGenes in the cancer module 459.

KAT2B REV3L MMP9 SMG7 UNC79 NUP54

2.26e-04431236MODULE_459
ComputationalGenes in the cancer module 378.

KAT2B REV3L MMP9 SMG7 UNC79 NUP54

2.38e-04435236MODULE_378
ComputationalGenes in the cancer module 317.

KAT2B REV3L MMP9 SMG7 UNC79 NUP54

2.53e-04440236MODULE_317
ComputationalGenes in the cancer module 255.

KAT2B REV3L MMP9 SMG7 UNC79 NUP54

2.86e-04450236MODULE_255
ComputationalBlood cells and cancer expression cancer.

KAT2B REV3L MMP9 SMG7 UNC79 NUP54

3.54e-04468236MODULE_179
ComputationalNeighborhood of MSH3

REV3L SLC16A5 UBE4B SLC18A1

1.61e-03243234MORF_MSH3
DiseaseCreutzfeldt-Jakob Disease, Familial

ALDH1A1 KRT73

8.82e-0513322C0751254
DiseaseThyroid Diseases

DIO1 TSHR

8.82e-0513322C0040128
DiseaseNew Variant Creutzfeldt-Jakob Disease

ALDH1A1 KRT73

8.82e-0513322C0376329
DiseaseCreutzfeldt-Jakob disease

ALDH1A1 KRT73

8.82e-0513322C0022336
Diseasemuscular atrophy (biomarker_via_orthology)

TIMM23 TIMM23B

4.54e-0429322DOID:767 (biomarker_via_orthology)
Diseasepresubiculum volume

REV3L ZNF423

5.20e-0431322EFO_0009400
Diseaserheumatoid arthritis (is_marker_for)

KAT2B MMP9

2.55e-0369322DOID:7148 (is_marker_for)
Diseaseesophagus squamous cell carcinoma (is_marker_for)

KAT2B MMP9

2.93e-0374322DOID:3748 (is_marker_for)
Diseaseresponse to anticonvulsant

ZNF521 SLC39A11

3.85e-0385322GO_0036277

Protein segments in the cluster

PeptideGeneStartEntry
SAQCPFGGFKMSGNG

ALDH1A1

461

P00352
PFGFSGVMAGTASCF

SLC7A4

231

O43246
GSRFAVPFGGFFSCT

MPEG1

521

Q2M385
DSLFMFPCGPSGGTS

NOBOX

556

O60393
FGFCPTRADSTVMGG

MMP9

326

P14780
TGCGTQMFFFVFLGG

OR10V1

96

Q8NGI7
FAGSMFGSVALGSVC

KRT73

81

Q86Y46
GGICFRMFPSQGFTE

KAT2B

556

Q92831
PVTMDSFFFGCELSG

NPM3

31

O75607
MGAAVFFGCTFVAFG

APH1A

1

Q96BI3
GVTPMFAVCFFGFGL

SLC25A20

81

O43772
MAFNFGAPSGTSGTA

NUP54

1

Q7Z3B4
FGSCTUPSFMFKFDQ

DIO1

121

P49895
ACFAGGMFALGADGS

MAN1A2

461

O60476
GMGFICGFSIATGAA

SLC44A1

41

Q8WWI5
MATSSGGFGAFAFFP

SLC39A11

66

Q8N1S5
AYTAGTFSMPFCGSS

OR14A2

156

Q96R54
GCAVGMAAGALFGTF

ROMO1

26

P60602
AFSMGSGYTFPAGVS

SMG7

676

Q92540
EMCPDGFFASGFSLK

VMO1

51

Q7Z5L0
LPGGCFFASDDSFAM

OXCT2

371

Q9BYC2
SDFAGGASGFPMTFS

CMAHP

201

Q9Y471
GASGFPMTFSGGKFT

CMAHP

206

Q9Y471
GYSGFVPFLSCQGMS

C10orf82

16

Q8WW14
RSFCFFGRGSGGSMP

ZFHX2

2471

Q9C0A1
GFITGLGMCFSFQSS

SLC16A5

111

O15375
TFGYTSANFSGRMPC

REV3L

2731

O60673
ISFGGMPCTSASFSG

TRO

811

Q12816
PGTSPMFCSVASFGA

UBE4B

251

O95155
GMGGTFKCPVCFTVF

ZNF521

1251

Q96K83
AFFTIGGCCMTGAAF

TIMM23B

76

Q5SRD1
SFEGMGGTFKCPVCF

ZNF423

1221

Q2M1K9
AFFTIGGCCMTGAAF

TIMM23

76

O14925
GPGCNTAGFFTVFAS

TSHR

491

P16473
AFCMGFAIGPSTGGA

SLC18A1

436

P54219
MFGFISCRFTGYPSS

UNC79

666

Q9P2D8