Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	chromatin binding	NCOA3 CHD7 MED1 AKAP8 ARID1A FOXA1 FOXA2 CREBBP SUPT5H MYOD1 MEIS1 FOXC1 FOXC2	2.08e-09	739	42	13	GO:0003682
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	NCOA3 MED1 AKAP8 ARID1A FOXA1 CREBBP MYOD1 ADD1 FOXC1	1.68e-07	417	42	9	GO:0061629
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	NCOA3 PLAGL2 CDX4 FOXA1 FOXA2 MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	1.82e-07	560	42	10	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	NCOA3 PLAGL2 CDX4 FOXA1 FOXA2 MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	2.01e-07	566	42	10	GO:0001216
GeneOntologyMolecularFunction	transcription factor binding	NCOA3 MED1 AKAP8 ARID1A FOXA1 FOXA2 CREBBP MYOD1 ADD1 FOXF2 FOXC1	3.00e-07	753	42	11	GO:0008134
GeneOntologyMolecularFunction	promoter-specific chromatin binding	CHD7 MED1 MYOD1 FOXC1 FOXC2	8.28e-07	83	42	5	GO:1990841
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXS1 NCOA3 CHD7 CDX4 MED1 GTF2IRD1 FOXA1 FOXA2 CREBBP MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	8.76e-07	1459	42	14	GO:0000977
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	NCOA3 MED1 AKAP8 ARID1A FOXA1 CREBBP MYOD1 ADD1 FOXC1	2.70e-06	582	42	9	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	FOXS1 CHD7 CDX4 MED1 GTF2IRD1 FOXA1 FOXA2 MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	6.24e-06	1244	42	12	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	FOXS1 CHD7 CDX4 MED1 GTF2IRD1 FOXA1 FOXA2 MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	7.77e-06	1271	42	12	GO:0000987
GeneOntologyMolecularFunction	protein domain specific binding	CACNA1D NCOA3 IRS1 IRS2 MED1 FOXA1 FOXA2 DNAJC6 ADAM12 CREBBP	1.02e-05	875	42	10	GO:0019904
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	NCOA3 MED1 CREBBP	1.12e-05	21	42	3	GO:0042975
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	FOXS1 NCOA3 PLAGL2 CDX4 GTF2IRD1 FOXA1 FOXA2 MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	2.25e-05	1412	42	12	GO:0000981
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD7 RAD54L2 ARID1A	6.40e-05	37	42	3	GO:0140658
GeneOntologyMolecularFunction	TFIIB-class transcription factor binding	CREBBP FOXF2	6.44e-05	6	42	2	GO:0001093
GeneOntologyMolecularFunction	metalloendopeptidase activity	MMP7 ADAMTS3 ADAMTS2 ADAM12	1.16e-04	120	42	4	GO:0004222
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase activator activity	IRS1 IRS2	1.54e-04	9	42	2	GO:0141038
GeneOntologyMolecularFunction	general transcription initiation factor binding	MED1 CREBBP FOXF2	3.30e-04	64	42	3	GO:0140296
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	NCOA3 CREBBP FOXF2	3.61e-04	66	42	3	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	NCOA3 CREBBP FOXF2	3.61e-04	66	42	3	GO:0001098
GeneOntologyMolecularFunction	chromatin DNA binding	MED1 CREBBP MYOD1 FOXC2	4.12e-04	167	42	4	GO:0031490
GeneOntologyMolecularFunction	transcription coactivator activity	BCL9L NCOA3 MED1 ARID1A CREBBP	4.18e-04	303	42	5	GO:0003713
GeneOntologyMolecularFunction	nuclear receptor binding	NCOA3 MED1 ARID1A MYOD1	6.31e-04	187	42	4	GO:0016922
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase regulator activity	IRS1 IRS2	6.47e-04	18	42	2	GO:0035014
GeneOntologyMolecularFunction	transmembrane receptor protein tyrosine kinase adaptor activity	IRS1 IRS2	6.47e-04	18	42	2	GO:0005068
GeneOntologyMolecularFunction	metallopeptidase activity	MMP7 ADAMTS3 ADAMTS2 ADAM12	8.12e-04	200	42	4	GO:0008237
GeneOntologyMolecularFunction	transcription coregulator activity	BCL9L NCOA3 RAD54L2 MED1 ARID1A CREBBP	1.07e-03	562	42	6	GO:0003712
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	CREBBP FOXF2	1.47e-03	27	42	2	GO:0001091
GeneOntologyMolecularFunction	insulin receptor binding	IRS1 IRS2	1.81e-03	30	42	2	GO:0005158
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	NCOA3 MED1	2.32e-03	34	42	2	GO:0046966
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	CHD7 RAD54L2 ARID1A	2.41e-03	127	42	3	GO:0008094
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	BCL9L NCOA3 IRS1 IRS2 RAD54L2 MED1 ARID1A CREBBP	2.55e-03	1160	42	8	GO:0030674
GeneOntologyMolecularFunction	bHLH transcription factor binding	CREBBP MYOD1	2.75e-03	37	42	2	GO:0043425
GeneOntologyMolecularFunction	disordered domain specific binding	NCOA3 CREBBP	3.05e-03	39	42	2	GO:0097718
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase binding	IRS1 IRS2	3.69e-03	43	42	2	GO:0043548
GeneOntologyMolecularFunction	histone acetyltransferase activity	NCOA3 CREBBP	5.16e-03	51	42	2	GO:0004402
GeneOntologyMolecularFunction	nuclear estrogen receptor binding	NCOA3 MED1	5.56e-03	53	42	2	GO:0030331
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	IRS1 IRS2	5.77e-03	54	42	2	GO:0030159
GeneOntologyMolecularFunction	transcription coactivator binding	MED1 CREBBP	5.77e-03	54	42	2	GO:0001223
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	NCOA3 CREBBP	5.98e-03	55	42	2	GO:0061733
GeneOntologyMolecularFunction	molecular adaptor activity	BCL9L NCOA3 IRS1 IRS2 RAD54L2 MED1 ARID1A CREBBP	6.58e-03	1356	42	8	GO:0060090
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	NCOA3 CREBBP	7.08e-03	60	42	2	GO:0034212
GeneOntologyMolecularFunction	nuclear receptor coactivator activity	NCOA3 MED1	7.31e-03	61	42	2	GO:0030374
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	BCL9L NCOA3 PLAGL2 CHD7 CDX4 RAD54L2 SSBP4 MED1 FOXA1 FOXA2 CREBBP SUPT5H MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	5.60e-10	1390	42	17	GO:0045944
GeneOntologyBiologicalProcess	embryo development	NCOA3 CHD7 CDX4 MED1 GTF2IRD1 ARID1A FOXA1 FOXA2 ADAMTS3 CREBBP MEIS1 ADD1 FOXF2 FOXC1 FOXC2	6.74e-08	1437	42	15	GO:0009790
GeneOntologyBiologicalProcess	striated muscle tissue development	BOC CHD7 MED1 ARID1A MYOD1 MEIS1 FOXC1 FOXC2	4.43e-07	349	42	8	GO:0014706
GeneOntologyBiologicalProcess	chordate embryonic development	NCOA3 CHD7 CDX4 MED1 ARID1A FOXA1 FOXA2 ADAMTS3 ADD1 FOXC1 FOXC2	1.35e-06	906	42	11	GO:0043009
GeneOntologyBiologicalProcess	muscle tissue development	BOC BCL9L CHD7 MED1 ARID1A MYOD1 MEIS1 FOXC1 FOXC2	1.46e-06	558	42	9	GO:0060537
GeneOntologyBiologicalProcess	cellular response to hormone stimulus	NCOA3 IRS1 IRS2 MED1 AKAP8 ARID1A FOXA1 GCLC MYOD1 FOXC2	1.47e-06	727	42	10	GO:0032870
GeneOntologyBiologicalProcess	positive regulation of intracellular estrogen receptor signaling pathway	NCOA3 MED1 FOXA1	1.71e-06	12	42	3	GO:0033148
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	NCOA3 CHD7 CDX4 MED1 ARID1A FOXA1 FOXA2 ADAMTS3 ADD1 FOXC1 FOXC2	1.73e-06	929	42	11	GO:0009792
GeneOntologyBiologicalProcess	tube development	NCOA3 CHD7 MED1 ARID1A FOXA1 FOXA2 ADAMTS2 ADAM12 MEIS1 ADD1 FOXF2 FOXC1 FOXC2	2.48e-06	1402	42	13	GO:0035295
GeneOntologyBiologicalProcess	cardiac muscle tissue development	CHD7 MED1 ARID1A MYOD1 MEIS1 FOXC1 FOXC2	3.95e-06	327	42	7	GO:0048738
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in outflow tract morphogenesis	FOXC1 FOXC2	4.05e-06	2	42	2	GO:1902257
GeneOntologyBiologicalProcess	estrogen receptor signaling pathway	NCOA3 MED1 ARID1A FOXA1	5.42e-06	57	42	4	GO:0030520
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue morphogenesis	CHD7 MED1 FOXC1 FOXC2	6.23e-06	59	42	4	GO:0055010
GeneOntologyBiologicalProcess	positive regulation of intracellular steroid hormone receptor signaling pathway	NCOA3 MED1 FOXA1	6.27e-06	18	42	3	GO:0033145
GeneOntologyBiologicalProcess	muscle structure development	BOC BCL9L CHD7 MED1 ARID1A ADAM12 MYOD1 MEIS1 FOXC1 FOXC2	6.45e-06	858	42	10	GO:0061061
GeneOntologyBiologicalProcess	cellular response to hepatocyte growth factor stimulus	MED1 GCLC CREBBP	7.44e-06	19	42	3	GO:0035729
GeneOntologyBiologicalProcess	positive regulation of keratinocyte differentiation	NCOA3 MED1 FOXC1	7.44e-06	19	42	3	GO:0045618
GeneOntologyBiologicalProcess	response to hepatocyte growth factor	MED1 GCLC CREBBP	1.02e-05	21	42	3	GO:0035728
GeneOntologyBiologicalProcess	embryonic morphogenesis	NCOA3 CHD7 MED1 ARID1A FOXA2 CREBBP FOXF2 FOXC1 FOXC2	1.07e-05	713	42	9	GO:0048598
GeneOntologyBiologicalProcess	tube morphogenesis	NCOA3 CHD7 MED1 ARID1A FOXA1 FOXA2 ADAM12 MEIS1 ADD1 FOXC1 FOXC2	1.08e-05	1125	42	11	GO:0035239
GeneOntologyBiologicalProcess	apoptotic process involved in outflow tract morphogenesis	FOXC1 FOXC2	1.21e-05	3	42	2	GO:0003275
GeneOntologyBiologicalProcess	regulation of apoptotic process involved in outflow tract morphogenesis	FOXC1 FOXC2	1.21e-05	3	42	2	GO:1902256
GeneOntologyBiologicalProcess	blood vessel development	FOXS1 CHD7 CDX4 MED1 ARID1A ADAM12 MEIS1 ADD1 FOXC1 FOXC2	1.29e-05	929	42	10	GO:0001568
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	FOXS1 CDX4 MED1 GTF2IRD1 ARID1A FOXA1 GCLC CREBBP SUPT5H FOXF2 FOXC1 FOXC2	1.48e-05	1399	42	12	GO:0045892
GeneOntologyBiologicalProcess	embryonic organ development	NCOA3 CHD7 CDX4 MED1 ARID1A FOXF2 FOXC1 FOXC2	1.49e-05	561	42	8	GO:0048568
GeneOntologyBiologicalProcess	tissue morphogenesis	NCOA3 CHD7 MED1 ARID1A FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.61e-05	750	42	9	GO:0048729
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	FOXS1 CDX4 MED1 GTF2IRD1 ARID1A FOXA1 GCLC CREBBP SUPT5H FOXF2 FOXC1 FOXC2	1.64e-05	1413	42	12	GO:1902679
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue development	CHD7 MED1 FOXC1 FOXC2	1.71e-05	76	42	4	GO:0003229
GeneOntologyBiologicalProcess	collagen fibril organization	ADAMTS3 ADAMTS2 FOXC1 FOXC2	1.71e-05	76	42	4	GO:0030199
GeneOntologyBiologicalProcess	cardiac muscle tissue morphogenesis	CHD7 MED1 FOXC1 FOXC2	1.80e-05	77	42	4	GO:0055008
GeneOntologyBiologicalProcess	vasculature development	FOXS1 CHD7 CDX4 MED1 ARID1A ADAM12 MEIS1 ADD1 FOXC1 FOXC2	1.86e-05	969	42	10	GO:0001944
GeneOntologyBiologicalProcess	cellular response to oxygen-containing compound	CACNA1D NCOA3 IRS1 IRS2 MED1 AKAP8 FOXA1 FOXA2 GCLC MYOD1 ADD1 FOXC2	2.12e-05	1450	42	12	GO:1901701
GeneOntologyBiologicalProcess	camera-type eye development	CHD7 MED1 ARID1A MEIS1 FOXF2 FOXC1 FOXC2	2.20e-05	426	42	7	GO:0043010
GeneOntologyBiologicalProcess	in utero embryonic development	NCOA3 CHD7 CDX4 MED1 FOXA2 ADAMTS3 ADD1 FOXC1	2.30e-05	596	42	8	GO:0001701
GeneOntologyBiologicalProcess	positive regulation of dopaminergic neuron differentiation	FOXA1 FOXA2	2.42e-05	4	42	2	GO:1904340
GeneOntologyBiologicalProcess	protein-DNA complex organization	NCOA3 CHD7 SETD1B RAD54L2 MED1 ARID1A FOXA1 FOXA2 CREBBP SUPT5H	2.42e-05	999	42	10	GO:0071824
GeneOntologyBiologicalProcess	positive regulation of epidermal cell differentiation	NCOA3 MED1 FOXC1	2.48e-05	28	42	3	GO:0045606
GeneOntologyBiologicalProcess	muscle organ development	BOC BCL9L CHD7 MED1 MYOD1 FOXC1 FOXC2	2.56e-05	436	42	7	GO:0007517
GeneOntologyBiologicalProcess	mesenchymal cell differentiation	BCL9L FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	2.82e-05	296	42	6	GO:0048762
GeneOntologyBiologicalProcess	cardiac ventricle morphogenesis	CHD7 MED1 FOXC1 FOXC2	3.06e-05	88	42	4	GO:0003208
GeneOntologyBiologicalProcess	animal organ morphogenesis	NCOA3 CHD7 CDX4 MED1 ARID1A FOXA1 FOXA2 MEIS1 FOXF2 FOXC1 FOXC2	3.34e-05	1269	42	11	GO:0009887
GeneOntologyBiologicalProcess	response to hormone	NCOA3 IRS1 IRS2 MED1 AKAP8 ARID1A FOXA1 GCLC MYOD1 FOXC2	3.48e-05	1042	42	10	GO:0009725
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	FOXS1 CDX4 MED1 GTF2IRD1 ARID1A FOXA1 CREBBP SUPT5H FOXC1 FOXC2	3.80e-05	1053	42	10	GO:0000122
GeneOntologyBiologicalProcess	muscle tissue morphogenesis	CHD7 MED1 FOXC1 FOXC2	3.80e-05	93	42	4	GO:0060415
GeneOntologyBiologicalProcess	positive regulation of epidermis development	NCOA3 MED1 FOXC1	4.10e-05	33	42	3	GO:0045684
GeneOntologyBiologicalProcess	eye development	CHD7 MED1 ARID1A MEIS1 FOXF2 FOXC1 FOXC2	4.72e-05	480	42	7	GO:0001654
GeneOntologyBiologicalProcess	visual system development	CHD7 MED1 ARID1A MEIS1 FOXF2 FOXC1 FOXC2	4.90e-05	483	42	7	GO:0150063
GeneOntologyBiologicalProcess	branching morphogenesis of an epithelial tube	NCOA3 MED1 FOXA1 FOXA2 FOXC2	4.94e-05	198	42	5	GO:0048754
GeneOntologyBiologicalProcess	regulation of intracellular estrogen receptor signaling pathway	NCOA3 MED1 FOXA1	5.35e-05	36	42	3	GO:0033146
GeneOntologyBiologicalProcess	sensory system development	CHD7 MED1 ARID1A MEIS1 FOXF2 FOXC1 FOXC2	5.44e-05	491	42	7	GO:0048880
GeneOntologyBiologicalProcess	muscle organ morphogenesis	CHD7 MED1 FOXC1 FOXC2	5.46e-05	102	42	4	GO:0048644
GeneOntologyBiologicalProcess	epithelial to mesenchymal transition	BCL9L FOXA1 FOXA2 FOXF2 FOXC1	5.56e-05	203	42	5	GO:0001837
GeneOntologyBiologicalProcess	glucose homeostasis	CACNA1D IRS1 IRS2 FOXA1 FOXA2 GCLC	5.91e-05	338	42	6	GO:0042593
GeneOntologyBiologicalProcess	carbohydrate homeostasis	CACNA1D IRS1 IRS2 FOXA1 FOXA2 GCLC	6.01e-05	339	42	6	GO:0033500
GeneOntologyBiologicalProcess	thelarche	NCOA3 MED1	6.04e-05	6	42	2	GO:0042695
GeneOntologyBiologicalProcess	mammary gland branching involved in thelarche	NCOA3 MED1	6.04e-05	6	42	2	GO:0060744
GeneOntologyBiologicalProcess	peptide secretion	CACNA1D IRS1 IRS2 CHD7 MMP7 FOXA2	6.41e-05	343	42	6	GO:0002790
GeneOntologyBiologicalProcess	chromatin organization	NCOA3 CHD7 SETD1B RAD54L2 ARID1A FOXA1 FOXA2 CREBBP SUPT5H	6.47e-05	896	42	9	GO:0006325
GeneOntologyBiologicalProcess	cardiac chamber development	CHD7 MED1 ARID1A FOXC1 FOXC2	6.83e-05	212	42	5	GO:0003205
GeneOntologyBiologicalProcess	developmental growth	FOXS1 NCOA3 CHD7 MED1 MYOD1 MEIS1 ADD1 FOXC1 FOXC2	7.36e-05	911	42	9	GO:0048589
GeneOntologyBiologicalProcess	regulation of keratinocyte differentiation	NCOA3 MED1 FOXC1	7.36e-05	40	42	3	GO:0045616
GeneOntologyBiologicalProcess	positive regulation of cell differentiation	BOC BCL9L NCOA3 MED1 ARID1A FOXA1 FOXA2 MYOD1 ADD1 FOXC1	7.48e-05	1141	42	10	GO:0045597
GeneOntologyBiologicalProcess	peptide transport	CACNA1D IRS1 IRS2 CHD7 MMP7 FOXA2	7.75e-05	355	42	6	GO:0015833
GeneOntologyBiologicalProcess	apoptotic process involved in heart morphogenesis	FOXC1 FOXC2	8.45e-05	7	42	2	GO:0003278
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in morphogenesis	FOXC1 FOXC2	8.45e-05	7	42	2	GO:1902338
GeneOntologyBiologicalProcess	mesenchyme development	BCL9L FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.00e-04	372	42	6	GO:0060485
GeneOntologyBiologicalProcess	circulatory system development	FOXS1 CHD7 CDX4 MED1 ARID1A ADAM12 MYOD1 MEIS1 ADD1 FOXC1 FOXC2	1.07e-04	1442	42	11	GO:0072359
GeneOntologyBiologicalProcess	chromatin remodeling	NCOA3 CHD7 SETD1B RAD54L2 ARID1A FOXA1 CREBBP SUPT5H	1.07e-04	741	42	8	GO:0006338
GeneOntologyBiologicalProcess	extracellular matrix organization	MMP7 ADAMTS3 ADAMTS2 FOXF2 FOXC1 FOXC2	1.08e-04	377	42	6	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	MMP7 ADAMTS3 ADAMTS2 FOXF2 FOXC1 FOXC2	1.09e-04	378	42	6	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	MMP7 ADAMTS3 ADAMTS2 FOXF2 FOXC1 FOXC2	1.11e-04	379	42	6	GO:0045229
GeneOntologyBiologicalProcess	negative regulation of apoptotic process involved in development	FOXC1 FOXC2	1.12e-04	8	42	2	GO:1904746
GeneOntologyBiologicalProcess	morphogenesis of a branching epithelium	NCOA3 MED1 FOXA1 FOXA2 FOXC2	1.13e-04	236	42	5	GO:0061138
GeneOntologyBiologicalProcess	cellular response to lipid	NCOA3 IRS1 MED1 AKAP8 ARID1A FOXA1 MYOD1 ADD1	1.14e-04	748	42	8	GO:0071396
GeneOntologyBiologicalProcess	formation of primary germ layer	ARID1A FOXA2 FOXC1 FOXC2	1.17e-04	124	42	4	GO:0001704
GeneOntologyBiologicalProcess	apoptotic process involved in development	XKR6 FOXC1 FOXC2	1.20e-04	47	42	3	GO:1902742
GeneOntologyBiologicalProcess	cellular response to steroid hormone stimulus	NCOA3 MED1 ARID1A FOXA1 MYOD1	1.20e-04	239	42	5	GO:0071383
GeneOntologyBiologicalProcess	regulation of epithelial to mesenchymal transition	BCL9L FOXA1 FOXA2 FOXC1	1.40e-04	130	42	4	GO:0010717
GeneOntologyBiologicalProcess	cellular response to thyroid hormone stimulus	MED1 GCLC	1.44e-04	9	42	2	GO:0097067
GeneOntologyBiologicalProcess	paraxial mesoderm formation	FOXC1 FOXC2	1.44e-04	9	42	2	GO:0048341
GeneOntologyBiologicalProcess	myoblast differentiation	BOC BCL9L ARID1A MYOD1	1.67e-04	136	42	4	GO:0045445
GeneOntologyBiologicalProcess	nuclear receptor-mediated steroid hormone signaling pathway	NCOA3 MED1 ARID1A FOXA1	1.67e-04	136	42	4	GO:0030518
GeneOntologyBiologicalProcess	collagen catabolic process	MMP7 ADAMTS3 ADAMTS2	1.71e-04	53	42	3	GO:0030574
GeneOntologyBiologicalProcess	morphogenesis of a branching structure	NCOA3 MED1 FOXA1 FOXA2 FOXC2	1.72e-04	258	42	5	GO:0001763
GeneOntologyBiologicalProcess	development of secondary female sexual characteristics	NCOA3 MED1	1.80e-04	10	42	2	GO:0046543
GeneOntologyBiologicalProcess	positive regulation of myoblast differentiation	BOC ARID1A MYOD1	1.81e-04	54	42	3	GO:0045663
GeneOntologyBiologicalProcess	amide transport	CACNA1D IRS1 IRS2 CHD7 MMP7 FOXA2	1.94e-04	420	42	6	GO:0042886
GeneOntologyBiologicalProcess	epithelial tube morphogenesis	NCOA3 MED1 ARID1A FOXA1 FOXA2 FOXC2	1.96e-04	421	42	6	GO:0060562
GeneOntologyBiologicalProcess	positive regulation of cell-cell adhesion mediated by cadherin	FOXA1 FOXA2	2.20e-04	11	42	2	GO:2000049
GeneOntologyBiologicalProcess	morphogenesis of an epithelium	NCOA3 MED1 ARID1A FOXA1 FOXA2 FOXF2 FOXC2	2.29e-04	619	42	7	GO:0002009
GeneOntologyBiologicalProcess	regulation of peptide hormone secretion	CACNA1D IRS1 IRS2 CHD7 FOXA2	2.39e-04	277	42	5	GO:0090276
GeneOntologyBiologicalProcess	regulation of peptide transport	CACNA1D IRS1 IRS2 CHD7 FOXA2	2.59e-04	282	42	5	GO:0090087
GeneOntologyBiologicalProcess	regulation of peptide secretion	CACNA1D IRS1 IRS2 CHD7 FOXA2	2.59e-04	282	42	5	GO:0002791
GeneOntologyBiologicalProcess	regulation of dopaminergic neuron differentiation	FOXA1 FOXA2	2.64e-04	12	42	2	GO:1904338
GeneOntologyBiologicalProcess	steroid hormone receptor signaling pathway	NCOA3 MED1 ARID1A FOXA1	2.75e-04	155	42	4	GO:0043401
GeneOntologyBiologicalProcess	regulation of epidermal cell differentiation	NCOA3 MED1 FOXC1	2.86e-04	63	42	3	GO:0045604
GeneOntologyBiologicalProcess	positive regulation of fatty acid beta-oxidation	IRS1 IRS2	3.11e-04	13	42	2	GO:0032000
GeneOntologyBiologicalProcess	development of secondary sexual characteristics	NCOA3 MED1	3.11e-04	13	42	2	GO:0045136
GeneOntologyBiologicalProcess	paraxial mesoderm morphogenesis	FOXC1 FOXC2	3.11e-04	13	42	2	GO:0048340
GeneOntologyBiologicalProcess	cardiac chamber morphogenesis	CHD7 MED1 FOXC1 FOXC2	3.18e-04	161	42	4	GO:0003206
GeneOntologyCellularComponent	chromatin	FOXS1 NCOA3 CHD7 CDX4 MED1 AKAP8 ARID1A FOXA1 FOXA2 CREBBP MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	1.20e-07	1480	43	15	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	BCL9L NCOA3 MED1 FOXA2 CREBBP MYOD1 MEIS1 FOXF2	2.50e-05	596	43	8	GO:0005667
HumanPheno	Square face	CHD7 SETD1B CREBBP	2.39e-05	16	19	3	HP:0000321
MousePheno	aorta coarctation	CHD7 ADAMTS3 FOXC1 FOXC2	2.60e-08	13	36	4	MP:0003387
MousePheno	aortic arch coarctation	CHD7 FOXC1 FOXC2	1.56e-07	5	36	3	MP:0010526
MousePheno	decreased circulating glucagon level	NCOA3 FOXA1 FOXA2 CREBBP	1.74e-07	20	36	4	MP:0002696
MousePheno	abnormal canal of Schlemm morphology	FOXF2 FOXC1 FOXC2	1.30e-06	9	36	3	MP:0005204
MousePheno	abnormal gland development	CACNA1D NCOA3 CHD7 MED1 FOXA1 ADAMTS3 FOXC1	1.81e-06	233	36	7	MP:0020973
MousePheno	abnormal muscle morphology	NCOA3 IRS2 CHD7 NDRG1 MED1 GTF2IRD1 ARID1A ADAMTS2 ADAM12 CREBBP MYOD1 FOXF2 FOXC2	1.83e-06	1106	36	13	MP:0002108
MousePheno	abnormal iris stroma morphology	FOXF2 FOXC1 FOXC2	1.86e-06	10	36	3	MP:0005208
MousePheno	abnormal trabecular meshwork morphology	FOXF2 FOXC1 FOXC2	1.86e-06	10	36	3	MP:0005203
MousePheno	abnormal periorbital region morphology	CHD7 GTF2IRD1 FOXC2	1.86e-06	10	36	3	MP:0030038
MousePheno	abnormal circulating glucagon level	NCOA3 FOXA1 FOXA2 CREBBP	3.17e-06	40	36	4	MP:0002695
MousePheno	ventricular septal defect	CHD7 ARID1A ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	3.83e-06	261	36	7	MP:0010402
MousePheno	abnormal neurocranium morphology	CHD7 GTF2IRD1 ADAMTS3 CREBBP FOXF2 FOXC1 FOXC2	4.68e-06	269	36	7	MP:0000074
MousePheno	absent soft palate	FOXF2 FOXC2	6.45e-06	2	36	2	MP:0030290
MousePheno	abnormal vascular development	CHD7 MED1 GTF2IRD1 ARID1A ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	6.83e-06	542	36	9	MP:0000259
MousePheno	embryonic lethality during organogenesis, complete penetrance	BCL9L CHD7 SETD1B RAD54L2 MED1 GTF2IRD1 ARID1A FOXA2 CREBBP MEIS1	7.22e-06	700	36	10	MP:0011098
MousePheno	embryonic lethality during organogenesis	BCL9L CHD7 SETD1B RAD54L2 MED1 GTF2IRD1 ARID1A FOXA2 CREBBP MEIS1 FOXC2	7.74e-06	876	36	11	MP:0006207
MousePheno	pale yolk sac	BCL9L MED1 GTF2IRD1 ARID1A CREBBP	8.55e-06	110	36	5	MP:0001722
MousePheno	abnormal fourth pharyngeal arch artery morphology	CHD7 FOXC1 FOXC2	1.04e-05	17	36	3	MP:0006354
MousePheno	abnormal pancreatic beta cell morphology	CACNA1D IRS1 IRS2 FOXA2 CREBBP	1.06e-05	115	36	5	MP:0005217
MousePheno	abnormal circulating free fatty acids level	NCOA3 IRS1 IRS2 CHD7 FOXA2 CREBBP	1.96e-05	222	36	6	MP:0001553
MousePheno	abnormal iridocorneal angle	FOXF2 FOXC1 FOXC2	2.02e-05	21	36	3	MP:0004221
MousePheno	abnormal interventricular septum morphology	CHD7 ARID1A ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	2.24e-05	342	36	7	MP:0000281
MousePheno	abnormal aqueous drainage system morphology	FOXF2 FOXC1 FOXC2	2.34e-05	22	36	3	MP:0005198
MousePheno	abnormal cardiovascular development	CHD7 MED1 GTF2IRD1 ARID1A FOXA2 ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	2.37e-05	802	36	10	MP:0002925
MousePheno	abnormal eye development	NCOA3 IRS2 CHD7 MED1 ARID1A FOXA2 COX5B FOXF2	2.43e-05	482	36	8	MP:0001286
MousePheno	abnormal triglyceride level	BOC NCOA3 PLAGL2 IRS1 IRS2 CHD7 FOXA1 FOXA2 CREBBP	2.55e-05	639	36	9	MP:0000187
MousePheno	abnormal free fatty acids level	NCOA3 IRS1 IRS2 CHD7 FOXA2 CREBBP	2.58e-05	233	36	6	MP:0010358
MousePheno	abnormal cranium morphology	NCOA3 CHD7 GTF2IRD1 FOXA2 ADAMTS3 ADAMTS2 CREBBP FOXF2 FOXC1 FOXC2	2.67e-05	813	36	10	MP:0000438
MousePheno	abnormal fourth pharyngeal arch morphology	CHD7 FOXC1 FOXC2	2.68e-05	23	36	3	MP:0006340
MousePheno	pallor	MED1 GTF2IRD1 ADAMTS3 CREBBP COX5B MEIS1	2.97e-05	239	36	6	MP:0003717
MousePheno	abnormal craniofacial bone morphology	NCOA3 CHD7 GTF2IRD1 FOXA2 ADAMTS3 ADAMTS2 CREBBP FOXF2 FOXC1 FOXC2	3.09e-05	827	36	10	MP:0002116
MousePheno	abnormal endocrine gland physiology	CACNA1D IRS1 IRS2 CHD7 MED1 FOXA1 FOXA2	3.28e-05	363	36	7	MP:0013561
MousePheno	abnormal circulating insulin level	CACNA1D NCOA3 IRS1 IRS2 CHD7 FOXA1 FOXA2 CREBBP	3.40e-05	505	36	8	MP:0001560
MousePheno	hemorrhage	FOXS1 CHD7 GTF2IRD1 ARID1A ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	3.46e-05	664	36	9	MP:0001914
MousePheno	abnormal mouth morphology	NCOA3 CHD7 GTF2IRD1 FOXA2 ADAMTS3 ADAMTS2 CREBBP FOXF2 FOXC2	3.71e-05	670	36	9	MP:0000452
MousePheno	abnormal axial skeleton morphology	NCOA3 CHD7 CDX4 RAD54L2 GTF2IRD1 FOXA2 ADAMTS3 ADAMTS2 CREBBP SUPT5H FOXF2 FOXC1 FOXC2	3.78e-05	1458	36	13	MP:0002114
MousePheno	abnormal angiogenesis	CHD7 MED1 ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	3.83e-05	372	36	7	MP:0000260
MousePheno	iris stroma hypoplasia	FOXC1 FOXC2	3.86e-05	4	36	2	MP:0006230
MousePheno	abnormal circulating triglyceride level	BOC NCOA3 PLAGL2 IRS1 IRS2 CHD7 FOXA1 FOXA2	3.96e-05	516	36	8	MP:0011969
MousePheno	abnormal gland physiology	FOXS1 CACNA1D IRS1 IRS2 CHD7 MED1 FOXA1 FOXA2 FOXC1	4.72e-05	691	36	9	MP:0002164
MousePheno	abnormal jaw morphology	NCOA3 GTF2IRD1 FOXA2 ADAMTS2 CREBBP FOXF2 FOXC1 FOXC2	4.79e-05	530	36	8	MP:0000454
MousePheno	abnormal prenatal growth/weight/body size	BCL9L NCOA3 IRS1 CHD7 SETD1B RAD54L2 MED1 GTF2IRD1 ARID1A FOXA2 GCLC CREBBP FOXC1	4.86e-05	1493	36	13	MP:0004196
MousePheno	abnormal heart septum morphology	CHD7 ARID1A ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	5.00e-05	388	36	7	MP:0006113
MousePheno	postnatal growth retardation	NCOA3 PLAGL2 IRS1 CHD7 MED1 GTF2IRD1 FOXA1 FOXA2 CREBBP FOXF2	5.30e-05	881	36	10	MP:0001732
MousePheno	decreased circulating hormone level	CACNA1D NCOA3 IRS2 CHD7 MED1 FOXA1 FOXA2 CREBBP	6.31e-05	551	36	8	MP:0014457
MousePheno	absent megakaryocytes	MED1 MEIS1	6.42e-05	5	36	2	MP:0008253
MousePheno	abnormal postnatal growth	NCOA3 PLAGL2 IRS1 CHD7 MED1 GTF2IRD1 FOXA1 FOXA2 CREBBP FOXF2	6.78e-05	907	36	10	MP:0001731
MousePheno	abnormal facial morphology	NCOA3 CHD7 GTF2IRD1 FOXA2 ADAMTS3 ADAMTS2 CREBBP FOXF2 FOXC1 FOXC2	6.97e-05	910	36	10	MP:0003743
MousePheno	abnormal insulin secretion	CACNA1D IRS1 IRS2 FOXA1 FOXA2	7.16e-05	171	36	5	MP:0003564
MousePheno	abnormal embryonic tissue morphology	CHD7 RAD54L2 MED1 GTF2IRD1 ARID1A FOXA2 ADAMTS3 GCLC CREBBP FOXC1 FOXC2	7.43e-05	1116	36	11	MP:0002085
MousePheno	abnormal head morphology	NCOA3 CHD7 MED1 GTF2IRD1 FOXA2 ADAMTS3 ADAMTS2 CREBBP FOXF2 FOXC1 FOXC2	7.68e-05	1120	36	11	MP:0000432
MousePheno	abnormal cranial foramen morphology	CHD7 FOXF2 FOXC1	8.12e-05	33	36	3	MP:0030310
MousePheno	abnormal endocrine pancreas secretion	CACNA1D IRS1 IRS2 FOXA1 FOXA2	8.21e-05	176	36	5	MP:0014195
MousePheno	abnormal fatty acids level	NCOA3 IRS1 IRS2 CHD7 FOXA2 CREBBP	8.57e-05	289	36	6	MP:0005280
MousePheno	abnormal adenohypophysis morphology	IRS2 CHD7 ADAMTS3 FOXC1	8.81e-05	92	36	4	MP:0004163
MousePheno	absent Schlemm's canal	FOXF2 FOXC1	9.61e-05	6	36	2	MP:0004226
MousePheno	hypoplastic trabecular meshwork	FOXF2 FOXC1	9.61e-05	6	36	2	MP:0004223
MousePheno	abnormal iris pigment epithelium	FOXC1 FOXC2	9.61e-05	6	36	2	MP:0005199
MousePheno	ciliary body hypoplasia	FOXF2 FOXC1	9.61e-05	6	36	2	MP:0013743
MousePheno	abnormal pancreas secretion	CACNA1D IRS1 IRS2 FOXA1 FOXA2	9.87e-05	183	36	5	MP:0002694
MousePheno	abnormal occipital bone morphology	GTF2IRD1 CREBBP FOXC1 FOXC2	9.98e-05	95	36	4	MP:0005269
MousePheno	abnormal sphenoid bone morphology	ADAMTS3 FOXF2 FOXC1 FOXC2	9.98e-05	95	36	4	MP:0000104
MousePheno	abnormal neural tube morphology	CHD7 RAD54L2 MED1 ARID1A FOXA2 CREBBP FOXC1 FOXC2	1.03e-04	591	36	8	MP:0002151
MousePheno	abnormal circulating hormone level	CACNA1D NCOA3 IRS1 IRS2 CHD7 MED1 GTF2IRD1 FOXA1 FOXA2 CREBBP	1.04e-04	954	36	10	MP:0005418
MousePheno	abnormal viscerocranium morphology	NCOA3 GTF2IRD1 FOXA2 ADAMTS2 CREBBP FOXF2 FOXC1 FOXC2	1.06e-04	593	36	8	MP:0005274
MousePheno	abnormal pituitary diverticulum morphology	CHD7 ADAMTS3 FOXC1	1.06e-04	36	36	3	MP:0003817
MousePheno	abnormal pancreatic islet morphology	CACNA1D IRS1 IRS2 FOXA2 CREBBP	1.18e-04	190	36	5	MP:0005215
MousePheno	abnormal endocrine pancreas morphology	CACNA1D IRS1 IRS2 FOXA2 CREBBP	1.21e-04	191	36	5	MP:0009165
MousePheno	abnormal adenohypophysis development	CHD7 ADAMTS3 FOXC1	1.24e-04	38	36	3	MP:0013337
MousePheno	increased carbon dioxide production	NCOA3 CHD7 FOXA2	1.24e-04	38	36	3	MP:0008963
MousePheno	absent frontal bone	GTF2IRD1 FOXC1	1.34e-04	7	36	2	MP:0004376
MousePheno	abnormal pancreatic beta cell physiology	CACNA1D IRS1 IRS2 FOXA1 FOXA2	1.36e-04	196	36	5	MP:0003562
MousePheno	abnormal thoracic cage morphology	CDX4 RAD54L2 ADAMTS3 ADAMTS2 CREBBP FOXC1 FOXC2	1.52e-04	463	36	7	MP:0004624
MousePheno	interrupted aortic arch	CHD7 FOXC1 FOXC2	1.56e-04	41	36	3	MP:0004157
MousePheno	abnormal endocrine pancreas physiology	CACNA1D IRS1 IRS2 FOXA1 FOXA2	1.57e-04	202	36	5	MP:0010147
MousePheno	abnormal pituitary gland development	CHD7 ADAMTS3 FOXC1	1.68e-04	42	36	3	MP:0003816
MousePheno	abnormal branching of the mammary ductal tree	NCOA3 MED1 FOXA1	1.68e-04	42	36	3	MP:0000662
MousePheno	decreased hormone level	CACNA1D NCOA3 IRS2 CHD7 MED1 FOXA1 FOXA2 CREBBP	1.70e-04	635	36	8	MP:0014455
MousePheno	periorbital edema	CHD7 FOXC2	1.79e-04	8	36	2	MP:0001788
MousePheno	interrupted aorta	CHD7 FOXC1 FOXC2	1.80e-04	43	36	3	MP:0010544
MousePheno	abnormal xiphoid process morphology	ADAMTS2 CREBBP FOXC1	2.07e-04	45	36	3	MP:0000159
MousePheno	decreased embryo size	BCL9L NCOA3 RAD54L2 MED1 GTF2IRD1 ARID1A FOXA2 CREBBP	2.19e-04	659	36	8	MP:0001698
MousePheno	abnormal blood circulation	FOXS1 CHD7 GTF2IRD1 ARID1A ADAMTS3 CREBBP MEIS1 FOXC1 FOXC2	2.21e-04	845	36	9	MP:0002128
MousePheno	abnormal ciliary process morphology	FOXF2 FOXC1	2.30e-04	9	36	2	MP:0014164
MousePheno	non-obstructive hydrocephaly	ADD1 FOXC1	2.30e-04	9	36	2	MP:0001893
MousePheno	abnormal glycogen level	NCOA3 IRS2 FOXA2 CREBBP	2.31e-04	118	36	4	MP:0005437
MousePheno	abnormal pharyngeal arch artery morphology	CHD7 FOXC1 FOXC2	2.35e-04	47	36	3	MP:0002672
MousePheno	abnormal estrous cycle	NCOA3 IRS2 CHD7 FOXA2	2.46e-04	120	36	4	MP:0001927
MousePheno	increased oxygen consumption	NCOA3 CHD7 FOXA2 CREBBP	2.54e-04	121	36	4	MP:0005289
MousePheno	increased triglyceride level	BOC NCOA3 PLAGL2 IRS1 IRS2 FOXA2	2.59e-04	354	36	6	MP:0005317
MousePheno	absent facial bone	GTF2IRD1 FOXC1 FOXC2	2.66e-04	49	36	3	MP:0030385
MousePheno	abnormal basicranium morphology	CHD7 ADAMTS3 FOXC1 FOXC2	2.70e-04	123	36	4	MP:0010029
MousePheno	abnormal hormone level	CACNA1D NCOA3 IRS1 IRS2 CHD7 MED1 GTF2IRD1 FOXA1 FOXA2 CREBBP	2.73e-04	1073	36	10	MP:0003953
MousePheno	abnormal embryonic growth/weight/body size	BCL9L NCOA3 CHD7 SETD1B RAD54L2 MED1 GTF2IRD1 ARID1A FOXA2 GCLC CREBBP	2.81e-04	1295	36	11	MP:0002088
MousePheno	absent supraoccipital bone	GTF2IRD1 FOXC2	2.86e-04	10	36	2	MP:0004443
MousePheno	abnormal soft palate morphology	FOXF2 FOXC2	2.86e-04	10	36	2	MP:0003154
MousePheno	polyovular ovarian follicle	IRS2 FOXC1	2.86e-04	10	36	2	MP:0009433
MousePheno	abnormal ovulation cycle	NCOA3 IRS2 CHD7 FOXA2	2.96e-04	126	36	4	MP:0009344
MousePheno	cleft secondary palate	CHD7 CREBBP FOXF2 FOXC2	3.06e-04	127	36	4	MP:0009890
MousePheno	abnormal visceral yolk sac morphology	BCL9L MED1 GTF2IRD1 ARID1A CREBBP	3.23e-04	236	36	5	MP:0001718
Domain	TF_fork_head_CS_2	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	7.81e-10	46	42	6	IPR030456
Domain	TF_fork_head_CS_1	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	8.94e-10	47	42	6	IPR018122
Domain	FORK_HEAD_3	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.16e-09	49	42	6	PS50039
Domain	FH	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.16e-09	49	42	6	SM00339
Domain	FORK_HEAD_1	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.16e-09	49	42	6	PS00657
Domain	FORK_HEAD_2	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.16e-09	49	42	6	PS00658
Domain	Forkhead	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.16e-09	49	42	6	PF00250
Domain	Fork_head_dom	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.16e-09	49	42	6	IPR001766
Domain	WHTH_DNA-bd_dom	FOXS1 GTF2IRD1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.03e-06	242	42	7	IPR011991
Domain	-	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	8.72e-06	218	42	6	1.10.10.10
Domain	Fork-head_N	FOXA1 FOXA2	1.48e-05	3	42	2	IPR013638
Domain	Forkhead_N	FOXA1 FOXA2	1.48e-05	3	42	2	PF08430
Domain	Forkhead_box_C	FOXA1 FOXA2	1.48e-05	3	42	2	IPR018533
Domain	HNF_C	FOXA1 FOXA2	1.48e-05	3	42	2	PF09354
Domain	MetalloPept_cat_dom	MMP7 ADAMTS3 ADAMTS2 ADAM12	3.24e-05	81	42	4	IPR024079
Domain	-	MMP7 ADAMTS3 ADAMTS2 ADAM12	3.24e-05	81	42	4	3.40.390.10
Domain	ZINC_PROTEASE	MMP7 ADAMTS3 ADAMTS2 ADAM12	6.85e-05	98	42	4	PS00142
Domain	Nuc_rcpt_coact	NCOA3 CREBBP	7.36e-05	6	42	2	IPR009110
Domain	Peptidase_M12B_N	ADAMTS3 ADAMTS2 ADAM12	9.13e-05	39	42	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS3 ADAMTS2 ADAM12	9.13e-05	39	42	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS3 ADAMTS2 ADAM12	9.86e-05	40	42	3	PS00427
Domain	ADAM_MEPRO	ADAMTS3 ADAMTS2 ADAM12	9.86e-05	40	42	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS3 ADAMTS2 ADAM12	9.86e-05	40	42	3	PS50214
Domain	Reprolysin	ADAMTS3 ADAMTS2 ADAM12	9.86e-05	40	42	3	PF01421
Domain	Peptidase_M12B	ADAMTS3 ADAMTS2 ADAM12	9.86e-05	40	42	3	IPR001590
Domain	Disintegrin_dom	ADAMTS3 ADAMTS2 ADAM12	1.06e-04	41	42	3	IPR001762
Domain	PTBI	IRS1 IRS2	2.68e-04	11	42	2	SM00310
Domain	IRS_PTB	IRS1 IRS2	3.21e-04	12	42	2	PS51064
Domain	IRS_PTB	IRS1 IRS2	4.42e-04	14	42	2	IPR002404
Domain	IRS	IRS1 IRS2	4.42e-04	14	42	2	PF02174
Domain	PLAC	ADAMTS3 ADAMTS2	8.24e-04	19	42	2	IPR010909
Domain	PLAC	ADAMTS3 ADAMTS2	8.24e-04	19	42	2	PS50900
Domain	ADAM_spacer1	ADAMTS3 ADAMTS2	1.21e-03	23	42	2	IPR010294
Domain	ADAM_spacer1	ADAMTS3 ADAMTS2	1.21e-03	23	42	2	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS3 ADAMTS2	1.32e-03	24	42	2	IPR013273
Domain	SNF2_N	CHD7 RAD54L2	2.35e-03	32	42	2	PF00176
Domain	SNF2_N	CHD7 RAD54L2	2.35e-03	32	42	2	IPR000330
Pathway	WP_FOXA2_PATHWAY	IRS1 IRS2 FOXA1 FOXA2	1.45e-07	21	33	4	M42579
Pathway	BIOCARTA_VDR_PATHWAY	NCOA3 MED1 ARID1A CREBBP	1.77e-07	22	33	4	MM1370
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	BOC CACNA1D NCOA3 KRTAP24-1 IRS2 MED1 ARID1A FOXA1 FOXA2 CREBBP MYOD1 MEIS1 FOXC1 FOXC2	1.49e-06	1432	33	14	M509
Pathway	PID_HNF3A_PATHWAY	NCOA3 FOXA1 FOXA2 CREBBP	3.16e-06	44	33	4	M285
Pathway	REACTOME_GASTRULATION	FOXA1 FOXA2 CREBBP FOXC1 FOXC2	1.15e-05	129	33	5	M46433
Pathway	BIOCARTA_VDR_PATHWAY	MED1 ARID1A CREBBP	2.29e-05	24	33	3	M13404
Pathway	WP_MESODERMAL_COMMITMENT_PATHWAY	FOXA1 FOXA2 MEIS1 FOXC1 FOXC2	2.62e-05	153	33	5	M39546
Pathway	REACTOME_IRS_ACTIVATION	IRS1 IRS2	5.29e-05	5	33	2	M27707
Pathway	BIOCARTA_PPARG_PATHWAY	MED1 CREBBP	1.11e-04	7	33	2	MM1573
Pathway	REACTOME_SOS_MEDIATED_SIGNALLING	IRS1 IRS2	1.11e-04	7	33	2	M19489
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	NCOA3 MMP7 MED1 FOXA1 CREBBP	1.47e-04	220	33	5	M27794
Pathway	BIOCARTA_PPARG_PATHWAY	MED1 CREBBP	1.47e-04	8	33	2	M22058
Pathway	REACTOME_FORMATION_OF_INTERMEDIATE_MESODERM	FOXC1 FOXC2	1.47e-04	8	33	2	M48014
Pathway	WP_HEART_DEVELOPMENT	FOXA2 FOXC1 FOXC2	1.66e-04	46	33	3	MM15884
Pathway	KEGG_TYPE_II_DIABETES_MELLITUS	CACNA1D IRS1 IRS2	1.77e-04	47	33	3	M19708
Pathway	WP_HEART_DEVELOPMENT	FOXA2 FOXC1 FOXC2	1.77e-04	47	33	3	M39610
Pathway	REACTOME_PI3K_AKT_ACTIVATION	IRS1 IRS2	1.89e-04	9	33	2	M714
Pathway	REACTOME_SIGNAL_ATTENUATION	IRS1 IRS2	2.36e-04	10	33	2	M14236
Pathway	REACTOME_SIGNALING_BY_LEPTIN	IRS1 IRS2	2.88e-04	11	33	2	M27195
Pathway	REACTOME_CYTOPROTECTION_BY_HMOX1	MED1 CREBBP COX5B	3.65e-04	60	33	3	M41830
Pathway	REACTOME_ESTROGEN_DEPENDENT_GENE_EXPRESSION	NCOA3 MED1 FOXA1 CREBBP	3.86e-04	149	33	4	M27888
Pathway	REACTOME_FORMATION_OF_AXIAL_MESODERM	FOXA1 FOXA2	4.75e-04	14	33	2	M46441
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	IRS1 IRS2 MMP7	4.84e-04	66	33	3	MM15925
Pathway	BIOCARTA_PITX2_PATHWAY	MED1 CREBBP	5.47e-04	15	33	2	MM1439
Pathway	WP_RUBINSTEINTAYBI_SYNDROME_1	NCOA3 CREBBP	5.47e-04	15	33	2	M48323
Pathway	REACTOME_SIGNALING_BY_NUCLEAR_RECEPTORS	NCOA3 MMP7 MED1 FOXA1 CREBBP	5.78e-04	296	33	5	M27869
Pathway	BIOCARTA_PITX2_PATHWAY	MED1 CREBBP	6.25e-04	16	33	2	M8516
Pathway	WP_LEPTININSULIN_SIGNALING_OVERLAP	IRS1 IRS2	7.07e-04	17	33	2	M39517
Pathway	REACTOME_COLLAGEN_FORMATION	MMP7 ADAMTS3 ADAMTS2	7.31e-04	76	33	3	MM14573
Pathway	REACTOME_RORA_ACTIVATES_GENE_EXPRESSION	MED1 CREBBP	7.94e-04	18	33	2	M26942
Pathway	REACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES	GCLC CREBBP	8.86e-04	19	33	2	M46442
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION	NCOA3 MED1 CREBBP	9.79e-04	84	33	3	M1008
Pathway	WP_BMP_SIGNALING_PATHWAY_IN_EYELID_DEVELOPMENT	FOXC1 FOXC2	9.83e-04	20	33	2	MM15907
Pathway	WP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT	FOXC1 FOXC2	9.83e-04	20	33	2	M39624
Pathway	WP_LEPTININSULIN_SIGNALING_OVERLAP	IRS1 IRS2	9.83e-04	20	33	2	MM15867
Pathway	REACTOME_FORMATION_OF_THE_URETERIC_BUD	FOXC1 FOXC2	1.09e-03	21	33	2	M48244
Pathway	WP_TRANSCRIPTION_FACTOR_REGULATION_IN_ADIPOGENESIS	IRS1 IRS2	1.19e-03	22	33	2	M39414
Pathway	WP_GDNFRET_SIGNALING_AXIS	FOXC1 FOXC2	1.19e-03	22	33	2	MM15887
Pathway	REACTOME_COLLAGEN_FORMATION	MMP7 ADAMTS3 ADAMTS2	1.20e-03	90	33	3	M631
Pathway	WP_GDNFRET_SIGNALING_AXIS	FOXC1 FOXC2	1.30e-03	23	33	2	M39814
Pathway	WP_ROLES_OF_CERAMIDES_IN_DEVELOPMENT_OF_INSULIN_RESISTANCE	IRS1 IRS2	1.30e-03	23	33	2	M45533
Pathway	REACTOME_CELLULAR_RESPONSE_TO_CHEMICAL_STRESS	MED1 GCLC CREBBP COX5B	1.40e-03	210	33	4	M41836
Pathway	REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING	IRS1 IRS2	1.42e-03	24	33	2	M519
Pathway	WP_EPO_RECEPTOR_SIGNALING	IRS1 IRS2	1.67e-03	26	33	2	M39687
Pathway	BIOCARTA_CARM_ER_PATHWAY	MED1 CREBBP	1.67e-03	26	33	2	M2499
Pathway	PID_HDAC_CLASSIII_PATHWAY	CREBBP MYOD1	1.67e-03	26	33	2	M32
Pathway	WP_EPO_RECEPTOR_SIGNALING	IRS1 IRS2	1.67e-03	26	33	2	MM15896
Pathway	SIG_IL4RECEPTOR_IN_B_LYPHOCYTES	IRS1 IRS2	1.80e-03	27	33	2	M1718
Pathway	REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_GENE_EXPRESSION	MED1 CREBBP	1.80e-03	27	33	2	M26943
Pathway	PID_IGF1_PATHWAY	IRS1 IRS2	2.07e-03	29	33	2	M125
Pathway	REACTOME_MYOGENESIS	BOC MYOD1	2.07e-03	29	33	2	M853
Pathway	WP_ANDROGEN_RECEPTOR_NETWORK_IN_PROSTATE_CANCER	NDRG1 ARID1A FOXA1	2.13e-03	110	33	3	M48043
Pathway	REACTOME_ADIPOGENESIS	NCOA3 MED1 CREBBP	2.13e-03	110	33	3	M48259
Pathway	PID_RETINOIC_ACID_PATHWAY	NCOA3 CREBBP	2.22e-03	30	33	2	M207
Pathway	WP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR	CREBBP SUPT5H	2.52e-03	32	33	2	M39521
Pathway	REACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA	NCOA3 MED1 CREBBP	2.60e-03	118	33	3	M27316
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	IRS1 IRS2	2.68e-03	33	33	2	M39503
Pathway	REACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS	NCOA3 CREBBP MEIS1	2.85e-03	122	33	3	M29689
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MMP7 ADAMTS3 ADAMTS2 ADAM12	2.95e-03	258	33	4	MM14572
Pathway	REACTOME_INTERLEUKIN_7_SIGNALING	IRS1 IRS2	3.19e-03	36	33	2	M542
Pathway	WP_22Q112_COPY_NUMBER_VARIATION_SYNDROME	FOXA2 FOXC1 FOXC2	3.42e-03	130	33	3	M39787
Pathway	WP_ADIPOGENESIS	IRS1 IRS2 FOXC2	3.49e-03	131	33	3	M39505
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	MMP7 MED1 FOXA1	3.64e-03	133	33	3	MM15529
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS3 ADAMTS2	3.73e-03	39	33	2	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS3 ADAMTS2	3.73e-03	39	33	2	MM15165
Pathway	PID_RET_PATHWAY	IRS1 IRS2	3.73e-03	39	33	2	M82
Pathway	PID_P53_DOWNSTREAM_PATHWAY	NDRG1 FOXA1 CREBBP	3.96e-03	137	33	3	M145
Pathway	WP_ADIPOGENESIS_GENES	IRS1 IRS2 FOXC2	3.96e-03	137	33	3	MM15970
Pathway	REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT	FOXA2 CREBBP	4.32e-03	42	33	2	M17541
Pathway	KEGG_ALDOSTERONE_REGULATED_SODIUM_REABSORPTION	IRS1 IRS2	4.32e-03	42	33	2	M16473
Pathway	REACTOME_ACTIVATION_OF_GENE_EXPRESSION_BY_SREBF_SREBP	MED1 CREBBP	4.32e-03	42	33	2	M27172
Pathway	WP_IL7_SIGNALING_PATHWAY	IRS1 IRS2	4.52e-03	43	33	2	MM15864
Pathway	WP_GENES_CONTROLLING_NEPHROGENESIS	FOXC1 FOXC2	4.73e-03	44	33	2	M39891
Pathway	REACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_DEATH_GENES	NDRG1 CREBBP	4.73e-03	44	33	2	M27499
Pathway	PID_HNF3B_PATHWAY	FOXA1 FOXA2	4.94e-03	45	33	2	M106
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MMP7 ADAMTS3 ADAMTS2 ADAM12	5.06e-03	300	33	4	M610
Pathway	REACTOME_KIDNEY_DEVELOPMENT	FOXC1 FOXC2	5.16e-03	46	33	2	M48243
Pathway	WP_NONALCOHOLIC_FATTY_LIVER_DISEASE	IRS1 IRS2 COX5B	5.59e-03	155	33	3	M39806
Pathway	PID_HEDGEHOG_GLI_PATHWAY	FOXA2 CREBBP	5.60e-03	48	33	2	M219
Pathway	PID_HES_HEY_PATHWAY	CREBBP MYOD1	5.60e-03	48	33	2	M288
Pathway	PID_AJDISS_2PATHWAY	MMP7 CREBBP	5.60e-03	48	33	2	M142
Pathway	REACTOME_IRS_MEDIATED_SIGNALLING	IRS1 IRS2	5.60e-03	48	33	2	M26916
Pathway	REACTOME_HEME_SIGNALING	MED1 CREBBP	5.83e-03	49	33	2	M41832
Pathway	WP_ID_SIGNALING_PATHWAY	IRS1 MYOD1	6.07e-03	50	33	2	MM15817
Pathway	SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES	IRS1 IRS2	6.31e-03	51	33	2	M7955
Pathway	REACTOME_CYTOPROTECTION_BY_HMOX1	MED1 COX5B	6.55e-03	52	33	2	MM15684
Pathway	BIOCARTA_PPARA_PATHWAY	MED1 CREBBP	6.55e-03	52	33	2	M2404
Pathway	WP_INTERFERON_TYPE_I_SIGNALING	IRS1 IRS2	7.05e-03	54	33	2	M39435
Pathway	WP_IL4_SIGNALING	IRS1 IRS2	7.05e-03	54	33	2	M39720
Pathway	REACTOME_SIGNALING_BY_TYPE_1_INSULIN_LIKE_GROWTH_FACTOR_1_RECEPTOR_IGF1R	IRS1 IRS2	7.05e-03	54	33	2	M27168
Pathway	REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE	IRS1 IRS2	7.05e-03	54	33	2	M620
Pathway	PID_IL2_1PATHWAY	IRS1 IRS2	7.30e-03	55	33	2	M122
Pathway	REACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS	MED1 CREBBP	7.30e-03	55	33	2	M27145
Pathway	REACTOME_REGULATION_OF_CHOLESTEROL_BIOSYNTHESIS_BY_SREBP_SREBF	MED1 CREBBP	7.30e-03	55	33	2	M27001
Pubmed	Six members of the mouse forkhead gene family are developmentally regulated.	FOXS1 FOXA1 FOXA2 FOXC1 FOXC2	6.76e-12	15	43	5	7689224
Pubmed	Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.	FOXA1 FOXA2 FOXC1 FOXC2	3.03e-11	6	43	4	8375339
Pubmed	Sonic hedgehog regulation of Foxf2 promotes cranial neural crest mesenchyme proliferation and is disrupted in cleft lip morphogenesis.	FOXA2 FOXF2 FOXC1 FOXC2	6.64e-10	11	43	4	28506991
Pubmed	Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.	FOXS1 FOXA1 FOXA2 FOXC1	3.65e-09	16	43	4	10208738
Pubmed	Screening and association testing of common coding variation in steroid hormone receptor co-activator and co-repressor genes in relation to breast cancer risk: the Multiethnic Cohort.	NCOA3 MED1 FOXA1 CREBBP	4.76e-09	17	43	4	19183483
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	FOXS1 NCOA3 PLAGL2 CDX4 SSBP4 MED1 FOXA1 CREBBP SUPT5H MYOD1 MEIS1	6.78e-09	877	43	11	20211142
Pubmed	Association between hepatocyte nuclear factor 6 (HNF-6) and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding.	FOXA1 FOXA2 CREBBP	7.04e-09	4	43	3	12509444
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXS1 NCOA3 PLAGL2 CDX4 FOXA1 FOXA2 MYOD1 MEIS1 FOXF2 FOXC1 FOXC2	9.70e-09	908	43	11	19274049
Pubmed	Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer.	FOXA2 FOXC1 FOXC2	1.76e-08	5	43	3	12533514
Pubmed	Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.	NCOA3 IRS1 IRS2 MED1 CREBBP ADD1 FOXC2	2.36e-08	250	43	7	18660489
Pubmed	Genetic determinants of insulin action in polycystic ovary syndrome.	IRS1 IRS2 FOXC2	3.51e-08	6	43	3	15926113
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	BCL9L NCOA3 CHD7 MED1 ARID1A FOXA1 CREBBP	3.79e-08	268	43	7	33640491
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA3 CHD7 MED1 ARID1A FOXC1	6.14e-08	83	43	5	28794006
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	FOXS1 AKAP8 MAP7D3 FOXA1 FOXA2 CREBBP MEIS1 FOXF2 FOXC1 FOXC2	7.19e-08	857	43	10	25609649
Pubmed	The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo.	MYOD1 FOXC1 FOXC2	9.82e-08	8	43	3	9106663
Pubmed	Human transcription factor protein interaction networks.	BCL9L NCOA3 CHD7 RAD54L2 SSBP4 AKAP8 ARID1A FOXA1 CREBBP MYOD1 COX5B FOXC1	1.04e-07	1429	43	12	35140242
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	PLAGL2 CDX4 NDRG1 GTF2IRD1 ARID1A FOXA1 CREBBP MEIS1 FOXC2	1.75e-07	709	43	9	22988430
Pubmed	Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program.	NCOA3 ARID1A CREBBP	2.88e-07	11	43	3	18003620
Pubmed	Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis.	MYOD1 FOXC1 FOXC2	2.88e-07	11	43	3	26839363
Pubmed	Requirement for Shh and Fox family genes at different stages in sweat gland development.	FOXA1 FOXA2 FOXC1	4.99e-07	13	43	3	19270025
Pubmed	Regulation of glucocorticoid receptor activity by 14--3-3-dependent intracellular relocalization of the corepressor RIP140.	NCOA3 MED1 CREBBP	4.99e-07	13	43	3	11266503
Pubmed	Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors.	MYOD1 FOXC1 FOXC2	7.93e-07	15	43	3	20059958
Pubmed	Deterministic and stochastic allele specific gene expression in single mouse blastomeres.	NCOA3 NDRG1 FOXA1 FOXA2 MYOD1 MEIS1 FOXC1	8.41e-07	424	43	7	21731673
Pubmed	PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development.	ADAMTS3 ADAMTS2 FOXC1 FOXC2	8.77e-07	59	43	4	38374152
Pubmed	Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules.	FOXA1 FOXA2 CREBBP	9.75e-07	16	43	3	22780989
Pubmed	Redundant roles of Tead1 and Tead2 in notochord development and the regulation of cell proliferation and survival.	FOXA1 FOXA2 FOXC1	9.75e-07	16	43	3	18332127
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA3 IRS2 CHD7 MED1 MAP7D3 ARID1A CREBBP COX5B	1.01e-06	638	43	8	31182584
Pubmed	Winged-helix, Hedgehog and Bmp genes are differentially expressed in distinct cell layers of the murine yolk sac.	FOXS1 FOXA1 FOXA2	1.42e-06	18	43	3	9152011
Pubmed	Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2.	IRS1 IRS2	1.49e-06	2	43	2	17222321
Pubmed	Insulin receptor substrate-1/2 mediates IL-4-induced migration of human airway epithelial cells.	IRS1 IRS2	1.49e-06	2	43	2	19447894
Pubmed	Divergent roles for IRS-1 and IRS-2 in breast cancer metastasis.	IRS1 IRS2	1.49e-06	2	43	2	17361103
Pubmed	Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.	FOXA1 FOXA2	1.49e-06	2	43	2	16467259
Pubmed	Super-Enhancer-Associated Transcription Factors Maintain Transcriptional Regulation in Mature Podocytes.	FOXC1 FOXC2	1.49e-06	2	43	2	33771836
Pubmed	Disruption of IRS-2 causes type 2 diabetes in mice.	IRS1 IRS2	1.49e-06	2	43	2	9495343
Pubmed	Phosphorylation of insulin receptor substrates (IRS-1 and IRS-2) is attenuated following cecal ligation and puncture in mice.	IRS1 IRS2	1.49e-06	2	43	2	37550630
Pubmed	Quantifying Protection in Disordered Proteins Using Millisecond Hydrogen Exchange-Mass Spectrometry and Peptic Reference Peptides.	NCOA3 CREBBP	1.49e-06	2	43	2	28675294
Pubmed	Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration.	FOXC1 FOXC2	1.49e-06	2	43	2	18187037
Pubmed	Insulin receptor substrate 1, but not IRS2, plays a dominant role in regulating pancreatic alpha cell function in mice.	IRS1 IRS2	1.49e-06	2	43	2	33839150
Pubmed	Roles of Insulin Receptor Substrates (IRS) in renal function and renal hemodynamics.	IRS1 IRS2	1.49e-06	2	43	2	33270683
Pubmed	Roles of insulin receptor substrates in insulin-induced stimulation of renal proximal bicarbonate absorption.	IRS1 IRS2	1.49e-06	2	43	2	15975995
Pubmed	The multifunctional role of the co-activator CBP in transcriptional regulation.	CREBBP MYOD1	1.49e-06	2	43	2	9238849
Pubmed	Systematic modeling for the insulin signaling network mediated by IRS(1) and IRS(2).	IRS1 IRS2	1.49e-06	2	43	2	24703981
Pubmed	Mouse forkhead (winged helix) gene LUN encodes a transactivator that acts in the lung.	FOXF2 FOXC2	1.49e-06	2	43	2	9676429
Pubmed	The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.	FOXA1 FOXA2	1.49e-06	2	43	2	34323272
Pubmed	Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.	IRS1 IRS2	1.49e-06	2	43	2	27708333
Pubmed	Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.	FOXA1 FOXA2	1.49e-06	2	43	2	26283356
Pubmed	Generation of conditional alleles for Foxc1 and Foxc2 in mice.	FOXC1 FOXC2	1.49e-06	2	43	2	22522965
Pubmed	Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.	FOXA1 FOXA2	1.49e-06	2	43	2	28938408
Pubmed	FOXC1 haploinsufficiency due to 6p25 deletion in a patient with rapidly progressing aortic valve disease.	FOXC1 FOXC2	1.49e-06	2	43	2	28657660
Pubmed	Impairment of bone healing by insulin receptor substrate-1 deficiency.	IRS1 IRS2	1.49e-06	2	43	2	14736890
Pubmed	Differential induction of HNF-3 transcription factors during neuronal differentiation.	FOXA1 FOXA2	1.49e-06	2	43	2	9260895
Pubmed	Foxf2: a novel locus for anterior segment dysgenesis adjacent to the Foxc1 gene.	FOXF2 FOXC1	1.49e-06	2	43	2	22022403
Pubmed	Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice.	IRS1 IRS2	1.49e-06	2	43	2	17928362
Pubmed	Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle.	IRS1 IRS2	1.49e-06	2	43	2	21356519
Pubmed	Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation.	FOXA1 FOXA2	1.49e-06	2	43	2	28235042
Pubmed	The study on the relationship between IRS-1 Gly972Arg and IRS-2 Gly1057Asp polymorphisms and type 2 diabetes in the Kurdish ethnic group in West Iran.	IRS1 IRS2	1.49e-06	2	43	2	22994406
Pubmed	Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis.	MMP7 FOXA2	1.49e-06	2	43	2	22268124
Pubmed	Caspase-mediated Cleavage of Insulin Receptor Substrate.	IRS1 IRS2	1.49e-06	2	43	2	15069074
Pubmed	Foxc1 and Foxc2 are necessary to maintain glomerular podocytes.	FOXC1 FOXC2	1.49e-06	2	43	2	28223138
Pubmed	The Irs1 branch of the insulin signaling cascade plays a dominant role in hepatic nutrient homeostasis.	IRS1 IRS2	1.49e-06	2	43	2	19596788
Pubmed	Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.	FOXA1 FOXA2	1.49e-06	2	43	2	34789735
Pubmed	Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.	FOXA1 FOXA2	1.49e-06	2	43	2	25249938
Pubmed	Insulin receptor substrate (IRS)-2, not IRS-1, protects human neuroblastoma cells against apoptosis.	IRS1 IRS2	1.49e-06	2	43	2	19259821
Pubmed	Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury.	IRS1 IRS2	1.49e-06	2	43	2	12810606
Pubmed	Overexpression of insulin receptor substrate-1, but not insulin receptor substrate-2, protects a T cell hybridoma from activation-induced cell death.	IRS1 IRS2	1.49e-06	2	43	2	12055235
Pubmed	Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome.	IRS1 IRS2	1.49e-06	2	43	2	11522686
Pubmed	Association of IRS1 (Gly972Arg) and IRS2 (Gly1057Asp) genes polymorphisms with OSA and NAFLD in Asian Indians.	IRS1 IRS2	1.49e-06	2	43	2	34449768
Pubmed	Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy.	MMP7 ADAM12	1.49e-06	2	43	2	19398663
Pubmed	Irs1 serine 307 promotes insulin sensitivity in mice.	IRS1 IRS2	1.49e-06	2	43	2	20074531
Pubmed	Role of IRS-2 in insulin and cytokine signalling.	IRS1 IRS2	1.49e-06	2	43	2	7675087
Pubmed	Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2.	FOXC1 FOXC2	1.49e-06	2	43	2	22493429
Pubmed	Selective insulin resistance with differential expressions of IRS-1 and IRS-2 in human NAFLD livers.	IRS1 IRS2	1.49e-06	2	43	2	29717275
Pubmed	Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver.	IRS1 IRS2	1.49e-06	2	43	2	11546755
Pubmed	Increased insulin resistance in obese children who have both 972 IRS-1 and 1057 IRS-2 polymorphisms.	IRS1 IRS2	1.49e-06	2	43	2	12475767
Pubmed	Variations in insulin secretion in carriers of gene variants in IRS-1 and -2.	IRS1 IRS2	1.49e-06	2	43	2	11872698
Pubmed	Essential role of insulin receptor substrate 1 (IRS-1) and IRS-2 in adipocyte differentiation.	IRS1 IRS2	1.49e-06	2	43	2	11259600
Pubmed	Relationship of insulin receptor substrate-1 and -2 genotypes to phenotypic features of polycystic ovary syndrome.	IRS1 IRS2	1.49e-06	2	43	2	12213887
Pubmed	Association of IRS-1 and IRS-2 genes polymorphisms with polycystic ovary syndrome: a meta-analysis.	IRS1 IRS2	1.49e-06	2	43	2	22523112
Pubmed	Selective Insulin Resistance in the Kidney.	IRS1 IRS2	1.49e-06	2	43	2	27247938
Pubmed	Decreased lactation capacity and altered milk composition in insulin receptor substrate null mice is associated with decreased maternal body mass and reduced insulin-dependent phosphorylation of mammary Akt.	IRS1 IRS2	1.49e-06	2	43	2	17641282
Pubmed	Night-Shift Work Duration and Risk of Colorectal Cancer According to IRS1 and IRS2 Expression.	IRS1 IRS2	1.49e-06	2	43	2	31666286
Pubmed	Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer.	FOXA1 FOXA2	1.49e-06	2	43	2	22265403
Pubmed	Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.	FOXA1 FOXA2	1.49e-06	2	43	2	15567715
Pubmed	Differential involvement of insulin receptor substrate (IRS)-1 and IRS-2 in brain insulin signaling is associated with the effects on amyloid pathology in a mouse model of Alzheimer's disease.	IRS1 IRS2	1.49e-06	2	43	2	34537327
Pubmed	Association of Gly972Arg variant of insulin receptor subtrate-1 and Gly1057Asp variant of insulin receptor subtrate-2 with polycystic ovary syndrome in the Chinese population.	IRS1 IRS2	1.49e-06	2	43	2	25310961
Pubmed	Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.	IRS1 IRS2	1.49e-06	2	43	2	26991655
Pubmed	Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.	IRS1 IRS2	1.49e-06	2	43	2	15572028
Pubmed	Association of IRS-1 and IRS-2 polymorphisms with predisposition to type-2 diabetes (T2D): a meta-analysis and trial sequential analysis.	IRS1 IRS2	1.49e-06	2	43	2	37173295
Pubmed	Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.	IRS1 IRS2	1.49e-06	2	43	2	25002528
Pubmed	Methylation specifies distinct estrogen-induced binding site repertoires of CBP to chromatin.	NCOA3 CREBBP	1.49e-06	2	43	2	21632823
Pubmed	The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.	FOXA1 FOXA2	1.49e-06	2	43	2	38821056
Pubmed	Targeting type 2 diabetes: lessons from a knockout model of insulin receptor substrate 2.	IRS1 IRS2	1.49e-06	2	43	2	24977713
Pubmed	Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation.	IRS1 IRS2	1.49e-06	2	43	2	28003360
Pubmed	FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells.	FOXA1 FOXA2	1.49e-06	2	43	2	36515690
Pubmed	Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice.	FOXA1 FOXA2	1.49e-06	2	43	2	19737569
Pubmed	Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.	FOXA1 FOXA2	1.49e-06	2	43	2	25211022
Pubmed	Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model.	CDX4 MEIS1	1.49e-06	2	43	2	17068127
Pubmed	Overexpression of Foxf2 in adipose tissue is associated with lower levels of IRS1 and decreased glucose uptake in vivo.	IRS1 FOXF2	1.49e-06	2	43	2	20009030
Pubmed	Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.	IRS1 IRS2	1.49e-06	2	43	2	11078455
Pubmed	PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates.	IRS1 IRS2	1.49e-06	2	43	2	21325637
Interaction	TLE3 interactions	BCL9L NCOA3 RAD54L2 NDRG1 SSBP4 AKAP8 ARID1A FOXA1 CREBBP MYOD1 FOXC1	1.58e-10	376	41	11	int:TLE3
Interaction	HOXD13 interactions	FOXS1 FOXA1 FOXA2 CREBBP MEIS1 FOXC1 FOXC2	2.86e-10	82	41	7	int:HOXD13
Interaction	GATA3 interactions	NCOA3 CHD7 MED1 AKAP8 ARID1A FOXA1 CREBBP FOXC1	3.48e-09	187	41	8	int:GATA3
Interaction	PAX7 interactions	NCOA3 CHD7 SSBP4 ARID1A CREBBP MYOD1 FOXC1	5.32e-09	124	41	7	int:PAX7
Interaction	PPP2R2D interactions	FOXS1 GTF2IRD1 SUPT5H COX5B FOXF2 FOXC1 FOXC2	4.37e-08	168	41	7	int:PPP2R2D
Interaction	HNF4A interactions	NCOA3 CHD7 RAD54L2 MED1 ARID1A FOXA2 CREBBP FOXC1	7.02e-08	275	41	8	int:HNF4A
Interaction	NFIA interactions	NCOA3 ARID1A FOXA1 CREBBP MYOD1 FOXC1 FOXC2	9.45e-08	188	41	7	int:NFIA
Interaction	SP7 interactions	BCL9L NCOA3 CHD7 AKAP8 ARID1A CREBBP COX5B FOXC1	1.52e-07	304	41	8	int:SP7
Interaction	HOXC13 interactions	FOXS1 MEIS1 FOXC1 FOXC2	1.52e-07	24	41	4	int:HOXC13
Interaction	HOXB13 interactions	FOXS1 FOXA2 MEIS1 FOXC2	1.81e-07	25	41	4	int:HOXB13
Interaction	PAX9 interactions	BCL9L NCOA3 PLAGL2 CHD7 ARID1A FOXC1	2.40e-07	130	41	6	int:PAX9
Interaction	PBX1 interactions	FOXA1 CREBBP MYOD1 MEIS1 FOXC1	7.88e-07	85	41	5	int:PBX1
Interaction	ONECUT1 interactions	FOXA1 FOXA2 CREBBP	9.29e-07	10	41	3	int:ONECUT1
Interaction	EGR2 interactions	BCL9L NCOA3 CHD7 RAD54L2 ARID1A CREBBP	1.20e-06	171	41	6	int:EGR2
Interaction	TLX1 interactions	NCOA3 CHD7 ARID1A CREBBP MEIS1 FOXC1	1.37e-06	175	41	6	int:TLX1
Interaction	TFF1 interactions	NCOA3 MED1 FOXA1 CREBBP	1.41e-06	41	41	4	int:TFF1
Interaction	GATA2 interactions	NCOA3 CHD7 MED1 ARID1A CREBBP FOXC1	2.90e-06	199	41	6	int:GATA2
Interaction	FEV interactions	NCOA3 CHD7 RAD54L2 ARID1A CREBBP FOXC1	3.25e-06	203	41	6	int:FEV
Interaction	RUNX1 interactions	MED1 ARID1A PLEKHB1 CREBBP MYOD1 FOXF2 FOXC1	3.66e-06	324	41	7	int:RUNX1
Interaction	TBXT interactions	NCOA3 CHD7 ARID1A CREBBP FOXC1	3.68e-06	116	41	5	int:TBXT
Interaction	HOXB9 interactions	FOXS1 FOXA1 CREBBP FOXC1 FOXC2	5.10e-06	124	41	5	int:HOXB9
Interaction	SMARCC2 interactions	NCOA3 CHD7 ARID1A FOXA1 CREBBP MYOD1 FOXC1	6.42e-06	353	41	7	int:SMARCC2
Interaction	NFIB interactions	NCOA3 ARID1A FOXA1 CREBBP FOXC1	9.89e-06	142	41	5	int:NFIB
Interaction	NCOA1 interactions	NCOA3 ARID1A FOXA2 CREBBP MYOD1	1.13e-05	146	41	5	int:NCOA1
Interaction	CREB1 interactions	FOXA1 CREBBP MYOD1 MEIS1 FOXC1 FOXC2	1.17e-05	254	41	6	int:CREB1
Interaction	SATB2 interactions	FOXS1 FOXA1 FOXA2 FOXC1 FOXC2	1.71e-05	159	41	5	int:SATB2
Interaction	ARID1A interactions	CHD7 ARID1A CREBBP SUPT5H MYOD1 FOXC1	1.88e-05	276	41	6	int:ARID1A
Interaction	AR interactions	BCL9L NCOA3 CHD7 RAD54L2 NDRG1 MED1 ARID1A FOXA1 CREBBP COX5B	2.22e-05	992	41	10	int:AR
Interaction	RXRA interactions	NCOA3 RAD54L2 MED1 CREBBP MYOD1	2.29e-05	169	41	5	int:RXRA
Interaction	SOX7 interactions	NCOA3 CHD7 ARID1A CREBBP	2.30e-05	82	41	4	int:SOX7
Interaction	TLX3 interactions	BCL9L NCOA3 CHD7 ARID1A MEIS1 FOXC1	2.53e-05	291	41	6	int:TLX3
Interaction	DLX5 interactions	FOXA1 FOXC1 FOXC2	2.75e-05	29	41	3	int:DLX5
Interaction	ARID1B interactions	NCOA3 ARID1A CREBBP SUPT5H MYOD1	2.86e-05	177	41	5	int:ARID1B
Interaction	GSC interactions	BCL9L NCOA3 FOXA2 CREBBP	2.90e-05	87	41	4	int:GSC
Interaction	NKX2-1 interactions	NCOA3 CHD7 FOXA1 FOXA2 CREBBP	3.10e-05	180	41	5	int:NKX2-1
Interaction	POU1F1 interactions	RAD54L2 MED1 CREBBP	3.38e-05	31	41	3	int:POU1F1
Interaction	FOXI1 interactions	NCOA3 ARID1A CREBBP FOXC1	3.62e-05	92	41	4	int:FOXI1
Interaction	HNF1B interactions	NCOA3 CHD7 ARID1A CREBBP FOXC1	4.02e-05	190	41	5	int:HNF1B
Interaction	SOX17 interactions	NCOA3 CHD7 ARID1A FOXC1	4.11e-05	95	41	4	int:SOX17
Interaction	SOX9 interactions	NCOA3 CHD7 ARID1A CREBBP	4.45e-05	97	41	4	int:SOX9
Interaction	LHX1 interactions	CHD7 SSBP4 ARID1A FOXA2	5.63e-05	103	41	4	int:LHX1
Interaction	DACH1 interactions	FOXA2 CREBBP FOXC1 FOXC2	5.85e-05	104	41	4	int:DACH1
Interaction	NFIC interactions	NCOA3 ARID1A FOXA1 CREBBP FOXC1	6.47e-05	210	41	5	int:NFIC
Interaction	RORA interactions	MED1 CREBBP MYOD1	6.79e-05	39	41	3	int:RORA
Interaction	PIAS1 interactions	NCOA3 PLAGL2 RAD54L2 GTF2IRD1 FOXA1 CREBBP	7.42e-05	353	41	6	int:PIAS1
Interaction	PAX8 interactions	NCOA3 CHD7 ARID1A CREBBP	7.54e-05	111	41	4	int:PAX8
Interaction	NR5A2 interactions	NCOA3 RAD54L2 FOXA1	7.90e-05	41	41	3	int:NR5A2
Interaction	TBR1 interactions	BCL9L NCOA3 CHD7 ARID1A	8.09e-05	113	41	4	int:TBR1
Interaction	FOXC2 interactions	AKAP8 FOXC1 FOXC2	8.49e-05	42	41	3	int:FOXC2
Interaction	ERG interactions	NCOA3 CHD7 RAD54L2 ARID1A CREBBP	8.59e-05	223	41	5	int:ERG
Interaction	LDB1 interactions	BCL9L SSBP4 FOXA1 FOXC1	8.66e-05	115	41	4	int:LDB1
Interaction	SATB1 interactions	FOXS1 FOXA1 FOXC1 FOXC2	8.95e-05	116	41	4	int:SATB1
Interaction	TP53BP1 interactions	NCOA3 RAD54L2 MED1 GTF2IRD1 ARID1A CREBBP ANXA11	8.96e-05	533	41	7	int:TP53BP1
Interaction	FOXC1 interactions	FOXS1 ARID1A MEIS1 FOXC1 FOXC2	9.54e-05	228	41	5	int:FOXC1
Interaction	ETS1 interactions	NCOA3 ARID1A CREBBP MEIS1	1.05e-04	121	41	4	int:ETS1
Interaction	NR3C1 interactions	NCOA3 IRS2 CHD7 RAD54L2 MED1 MAP7D3 ARID1A CREBBP COX5B	1.20e-04	974	41	9	int:NR3C1
Interaction	C5orf24 interactions	MEIS1 FOXC1 FOXC2	1.27e-04	48	41	3	int:C5orf24
Interaction	CRX interactions	BCL9L NCOA3 CHD7 ARID1A CREBBP	1.58e-04	254	41	5	int:CRX
Interaction	MEIS1 interactions	CREBBP MEIS1 FOXC1	1.61e-04	52	41	3	int:MEIS1
Interaction	ESRRB interactions	NCOA3 RAD54L2 MED1 AKAP8 ARID1A	1.83e-04	262	41	5	int:ESRRB
Interaction	GTF2B interactions	NCOA3 MED1 CREBBP FOXF2	1.90e-04	141	41	4	int:GTF2B
Interaction	LDB2 interactions	SSBP4 FOXA1 CREBBP	2.01e-04	56	41	3	int:LDB2
Interaction	NUP35 interactions	BCL9L NCOA3 AKAP8 ARID1A FOXA2 CREBBP	2.02e-04	424	41	6	int:NUP35
Interaction	NCOA6 interactions	SETD1B MED1 FOXA1 CREBBP	2.12e-04	145	41	4	int:NCOA6
Interaction	NR2F1 interactions	FOXS1 NCOA3 FOXC2	2.23e-04	58	41	3	int:NR2F1
Interaction	ETS2 interactions	NCOA3 NDRG1 CREBBP	2.59e-04	61	41	3	int:ETS2
Interaction	SMAD3 interactions	NCOA3 IRS1 GTF2IRD1 ARID1A CREBBP MYOD1	2.68e-04	447	41	6	int:SMAD3
Interaction	HOXA10 interactions	CREBBP MEIS1 FOXC1	2.72e-04	62	41	3	int:HOXA10
Interaction	SMARCE1 interactions	NCOA3 CHD7 ARID1A MYOD1 FOXC1	2.79e-04	287	41	5	int:SMARCE1
Interaction	RBBP5 interactions	CHD7 SETD1B ARID1A CREBBP MYOD1	2.79e-04	287	41	5	int:RBBP5
Interaction	TRIM33 interactions	NCOA3 SSBP4 FOXA1 CREBBP MYOD1 FOXF2	2.88e-04	453	41	6	int:TRIM33
Interaction	YAP1 interactions	BCL9L NDRG1 MED1 MAP7D3 ARID1A FOXA1 CREBBP ADD1 FOXC1	2.89e-04	1095	41	9	int:YAP1
Interaction	KDM6A interactions	SETD1B FOXA1 CREBBP MYOD1	3.23e-04	162	41	4	int:KDM6A
Interaction	PPP2R2A interactions	FOXS1 NDRG1 CREBBP FOXC1 FOXC2	3.47e-04	301	41	5	int:PPP2R2A
Interaction	LHX4 interactions	BCL9L CHD7 SSBP4 ARID1A	3.55e-04	166	41	4	int:LHX4
Interaction	GCM1 interactions	NCOA3 ARID1A CREBBP	3.57e-04	68	41	3	int:GCM1
Interaction	ETV4 interactions	NCOA3 ARID1A CREBBP	3.73e-04	69	41	3	int:ETV4
Interaction	KMT2D interactions	SETD1B CREBBP SUPT5H MYOD1	3.79e-04	169	41	4	int:KMT2D
Interaction	EP300 interactions	NCOA3 SSBP4 MED1 AKAP8 TMC5 ARID1A CREBBP SUPT5H MYOD1 FOXC1	3.91e-04	1401	41	10	int:EP300
Interaction	GATA1 interactions	MED1 AKAP8 ARID1A CREBBP	3.97e-04	171	41	4	int:GATA1
Interaction	EWSR1 interactions	BCL9L NCOA3 NDRG1 AKAP8 ARID1A CREBBP ANXA11 FOXC1	4.12e-04	906	41	8	int:EWSR1
Interaction	TEAD1 interactions	CHD7 ARID1A CREBBP FOXC1	4.42e-04	176	41	4	int:TEAD1
Interaction	PTEN interactions	NCOA3 IRS1 AKAP8 ARID1A GCLC CREBBP COX5B ANXA11	4.87e-04	929	41	8	int:PTEN
Interaction	CARM1 interactions	NCOA3 ARID1A CREBBP SUPT5H MYOD1	4.92e-04	325	41	5	int:CARM1
Interaction	LHX2 interactions	BCL9L CHD7 SSBP4 ARID1A	5.12e-04	183	41	4	int:LHX2
Interaction	LHX3 interactions	CHD7 SSBP4 ARID1A CREBBP	5.34e-04	185	41	4	int:LHX3
Interaction	ADAM2 interactions	ADAMTS2 ADAM12	5.39e-04	17	41	2	int:ADAM2
Interaction	UBP1 interactions	FOXA1 FOXC1 FOXC2	5.55e-04	79	41	3	int:UBP1
Interaction	FOXJ2 interactions	AKAP8 FOXF2 FOXC1	5.97e-04	81	41	3	int:FOXJ2
Interaction	DLX1 interactions	CDX4 FOXA1	6.05e-04	18	41	2	int:DLX1
Interaction	PPARGC1A interactions	MED1 CREBBP MYOD1	6.19e-04	82	41	3	int:PPARGC1A
Interaction	MYOD1 interactions	NCOA3 ARID1A CREBBP MYOD1	6.38e-04	194	41	4	int:MYOD1
Interaction	IRF4 interactions	NCOA3 CHD7 ARID1A	6.88e-04	85	41	3	int:IRF4
Interaction	NIPBL interactions	AKAP8 MAP7D3 SUPT5H MYOD1	7.02e-04	199	41	4	int:NIPBL
Interaction	BCL9 interactions	BCL9L SSBP4 MYOD1	7.11e-04	86	41	3	int:BCL9
Interaction	FOXS1 interactions	FOXS1 AKAP8 FOXC1	7.11e-04	86	41	3	int:FOXS1
Interaction	TFAP2D interactions	RAD54L2 ADAM12 CREBBP	7.86e-04	89	41	3	int:TFAP2D
Interaction	NCOR1 interactions	NCOA3 CREBBP SUPT5H MYOD1 FOXC1	8.11e-04	363	41	5	int:NCOR1
Interaction	TERF2IP interactions	CHD7 MED1 ARID1A CREBBP SUPT5H FOXC1	8.18e-04	552	41	6	int:TERF2IP
Interaction	HOXB4 interactions	CREBBP MEIS1	8.27e-04	21	41	2	int:HOXB4
Cytoband	20q11.21	FOXS1 PLAGL2	9.02e-04	47	43	2	20q11.21
Cytoband	19p13.1	SSBP4 AKAP8	9.40e-04	48	43	2	19p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr6p25	FOXF2 FOXC1	3.40e-03	92	43	2	chr6p25
GeneFamily	Forkhead boxes	FOXS1 FOXA1 FOXA2 FOXF2 FOXC1 FOXC2	1.09e-10	43	32	6	508
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	NCOA3 CREBBP	4.06e-04	17	32	2	486
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS3 ADAMTS2	5.09e-04	19	32	2	50
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	IRS1 IRS2 PLEKHB1	5.67e-03	206	32	3	682
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#3_top-relative-expression-ranked_1000	BOC IRS1 CHD7 MEIS1	2.59e-05	89	41	4	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k3_1000
CoexpressionAtlas	e10.5_Nasal_Pit_top-relative-expression-ranked_500_3	IRS2 CHD7	5.43e-05	6	41	2	Facebase_ST1_e10.5_Nasal_Pit_500_3
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#3_top-relative-expression-ranked_200	CHD7 FOXC1 FOXC2	8.96e-05	45	41	3	gudmap_developingKidney_e13.5_podocyte cells_200_k3
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500	BOC MED1 FOXA1 ADAMTS2 MYOD1 MEIS1	9.38e-05	388	41	6	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	NCOA3 CHD7 ARID1A CREBBP MEIS1 ADD1 FOXC1 FOXC2	1.41e-04	815	41	8	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000	BOC IRS1 ADAMTS3 ADAMTS2 MEIS1	1.51e-04	265	41	5	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	XKR6 ADAMTS2 ANXA11 FOXC1 FOXC2	7.81e-07	178	43	5	9fc5688cf705a74398d24e10e0aab4758612e72b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC1 FOXC2	8.25e-07	180	43	5	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC1 FOXC2	8.71e-07	182	43	5	fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell	(5)_Epithelial_cells-(5)_Glands_duct\|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MMP7 TMC5 PLEKHB1 FOXC1 FOXC2	9.70e-07	186	43	5	219b1aeca17503244fabbb780bca58f22c7c0f27
ToppCell	(5)_Glands_duct\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MMP7 TMC5 PLEKHB1 FOXC1 FOXC2	9.70e-07	186	43	5	ad8d5010e5095508f4995e0c6c016a44e8ffb8dd
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC1 FOXC2	1.13e-06	192	43	5	09cb5b89a164ac7444774ccc8c90323c8ea2026b
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Club\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	MMP7 NDRG1 TMC5 FOXA1 FOXA2	1.13e-06	192	43	5	044c7ae56da17cacf2705efa8ac2c8aeba6cfeee
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	BOC ADAMTS3 LINC00477 FOXC1 FOXC2	1.13e-06	192	43	5	3a6f2c255da46a0b0f5b657b0f56f3d7798ae85a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC1 FOXC2	1.16e-06	193	43	5	dd4bac8a93a5b9dcf7301f1d7d6e3eb6670f5c68
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC1 FOXC2	1.16e-06	193	43	5	2ddf9b2770a0be9689e01d1a3d19e4a6d42c7a50
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC1 FOXC2	1.25e-06	196	43	5	7acd782a587b7d331517f60daa8b5c2177bedfc7
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 MMP7 ADAMTS2 FOXF2 FOXC2	1.32e-06	198	43	5	eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 MMP7 ADAMTS2 FOXF2 FOXC2	1.32e-06	198	43	5	8b9e8eaeffda40912a0163fdf39b93bc5e64751c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 FOXF2 FOXC1 FOXC2	1.66e-05	159	43	4	7a5c94c87b73f928d4daee507f32cbe7d90e4478
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 FOXF2 FOXC1 FOXC2	1.79e-05	162	43	4	c5eee02836efde2108534679850c28d2b2cfce3f
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC MMP7 FOXC1 FOXC2	1.84e-05	163	43	4	f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC MMP7 FOXC1 FOXC2	1.84e-05	163	43	4	a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell	5'-Airway_Nasal_SMG\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC MMP7 FOXC1 FOXC2	1.84e-05	163	43	4	d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell	5'-Airway_Nasal_SMG-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC MMP7 FOXC1 FOXC2	1.84e-05	163	43	4	454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC MMP7 FOXC1 FOXC2	1.84e-05	163	43	4	be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	BOC MMP7 FOXC1 FOXC2	1.84e-05	163	43	4	d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	CACNA1D TMC5 FOXA2 PLEKHB1	2.16e-05	170	43	4	d682178d11d67eb5a02d0c6b3967645e37bcc62a
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma\|TCGA-Cervix / Sample_Type by Project: Shred V9	CACNA1D TMC5 FOXA2 PLEKHB1	2.21e-05	171	43	4	1af575809b3334bfaa019ff26c56e6cb03c82ee8
ToppCell	COVID-19-kidney-REN+Pericyte\|kidney / Disease (COVID-19 only), tissue and cell type	FOXS1 ADAM12 MEIS1 FOXC2	2.65e-05	179	43	4	342c1cc4444f51b8dcb30d3adc98285a25669c6e
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP7 MEIS1 FOXC1 FOXC2	2.65e-05	179	43	4	ec331b1132f965581f851a3b29e62873c4140e6c
ToppCell	15-Airway-Epithelial-Submucosal_gland\|Airway / Age, Tissue, Lineage and Cell class	MMP7 FOXA1 PLEKHB1 FOXC1	2.71e-05	180	43	4	283bb0d58811947bfda4e286b9ec87d869c8e29e
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXA1 FOXA2 PLEKHB1 GCLC	2.71e-05	180	43	4	d553aba594f5304f1c09ff9c6d49b64cd7ee7850
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP7 COX5B MEIS1 FOXC1	2.83e-05	182	43	4	9b556e44ed6aaa50ec572224f5751fb02ce63438
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MMP7 COX5B MEIS1 FOXC1	2.83e-05	182	43	4	2f7d9c0bf7155ac376e63fc9d9542b5c3ab89f04
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXS1 ADAMTS2 FOXC1 FOXC2	2.89e-05	183	43	4	b4f29dd3994009bb5eb769d36d95886664e7f87d
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BOC CACNA1D MEIS1 FOXC2	2.89e-05	183	43	4	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Serous\|World / shred by cell class for bronchial biopsy	IRS2 MMP7 PLEKHB1 FOXC1	2.95e-05	184	43	4	09d0d1525c11dd326efd942684c03f79d992cf3b
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLEKHB1 COX5B MEIS1 FOXC1	2.95e-05	184	43	4	00db9eaaffe9c598222e14b2f9638cbcce1602d7
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXS1 BOC ADAMTS2 MEIS1	3.01e-05	185	43	4	eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXS1 BOC ADAMTS2 MEIS1	3.01e-05	185	43	4	f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCell	facs-Thymus-Epithelium-24m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXS1 BOC ADAMTS2 MEIS1	3.01e-05	185	43	4	ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	BOC ADAMTS2 MEIS1 FOXC2	3.01e-05	185	43	4	c85bba1210f1d389add3e40be9b96abac40cf8c1
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	BOC CACNA1D ADAMTS2 MEIS1	3.01e-05	185	43	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	XKR6 NDRG1 TMC5 FOXA1	3.08e-05	186	43	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FOXA1 FOXA2 MYADML2 PLEKHB1	3.08e-05	186	43	4	dfd67d67c103c942de6c8acef8d81e57a9886154
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CHD7 FOXA1 FOXA2 PLEKHB1	3.14e-05	187	43	4	ab6f4d387218b4651fdadbf269806c1ddc96a1d2
ToppCell	E12.5-Epithelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CHD7 FOXA1 FOXA2 PLEKHB1	3.14e-05	187	43	4	29ea5e14dac3321df76f6aa4f053068b49c4a4bf
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)\|368C / Donor, Lineage, Cell class and subclass (all cells)	PLAGL2 TMC5 FOXA1 FOXA2	3.14e-05	187	43	4	b827d9da7032bf051756ddf88352af922eb0f87b
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1D NDRG1 MEIS1 FOXF2	3.14e-05	187	43	4	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	368C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PLAGL2 TMC5 FOXA1 FOXA2	3.14e-05	187	43	4	61c00604dda8b36a5c3eea6554e5601aa1b884f7
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	BOC IRS1 MEIS1 FOXC1	3.21e-05	188	43	4	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	BOC CACNA1D MEIS1 FOXF2	3.21e-05	188	43	4	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	P07-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FOXS1 ADAMTS2 FOXC1 FOXC2	3.21e-05	188	43	4	6ec22b79b19d57ea187f312907819dc2d01f3efe
ToppCell	Striatum-Endothelial\|Striatum / BrainAtlas - Mouse McCarroll V32	FOXS1 FOXF2 FOXC1 FOXC2	3.27e-05	189	43	4	95ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CHD7 NDRG1 PLEKHB1 MEIS1	3.27e-05	189	43	4	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	P03-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FOXS1 ADAMTS2 FOXC1 FOXC2	3.27e-05	189	43	4	b5439ef221106f6d54434f268485e9bb17b39102
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXS1 MEIS1 FOXC1 FOXC2	3.34e-05	190	43	4	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC5 FOXA1 FOXA2 PLEKHB1	3.34e-05	190	43	4	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC ADAMTS3 ADAMTS2 FOXC1	3.34e-05	190	43	4	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ADAMTS2 ADAM12 MEIS1	3.34e-05	190	43	4	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXS1 ADAMTS2 FOXC1 FOXC2	3.41e-05	191	43	4	9431ffd6b758f756609d9057de2023596e22b5d4
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	BOC CACNA1D ADAM12 MEIS1	3.41e-05	191	43	4	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	367C-Epithelial_cells\|367C / Donor, Lineage, Cell class and subclass (all cells)	MMP7 TMC5 FOXA1 FOXA2	3.41e-05	191	43	4	d31975fc33779b0b3ff1a50d7c64fec8d08be4d4
ToppCell	facs-Lung-EPCAM-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXA1 FOXA2 PLEKHB1 GCLC	3.41e-05	191	43	4	629007189034ee8451411428f1c6cc57daee2d91
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRS1 MEIS1 FOXF2 FOXC2	3.41e-05	191	43	4	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXA1 FOXA2 PLEKHB1 GCLC	3.48e-05	192	43	4	13e4b17d7a592604140777aca235f795df6b3f91
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ADAMTS3 ADAMTS2 MEIS1	3.48e-05	192	43	4	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC CACNA1D ADAMTS2 MEIS1	3.48e-05	192	43	4	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXA1 FOXA2 PLEKHB1 GCLC	3.48e-05	192	43	4	f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCell	Hippocampus-Endothelial\|Hippocampus / BrainAtlas - Mouse McCarroll V32	FOXS1 FOXF2 FOXC1 FOXC2	3.48e-05	192	43	4	36deadab892d3e639a71f33697bb2d3cbbaa5372
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC ADAMTS2 ADAM12 MEIS1	3.48e-05	192	43	4	d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCell	facs-Lung-24m-Epithelial\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXA1 FOXA2 PLEKHB1 GCLC	3.48e-05	192	43	4	ebfd8209a7353fbccb8ca7ade14b4f25822cebd2
ToppCell	droplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXA1 FOXA2 PLEKHB1 GCLC	3.48e-05	192	43	4	6244541688f85917018a057aa0b3e5972934dfbc
ToppCell	facs-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXA1 FOXA2 PLEKHB1 GCLC	3.48e-05	192	43	4	cca2d0fedfbd946c54d6f4fc45887117c8dae58a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ADAMTS3 ADAMTS2 MEIS1	3.48e-05	192	43	4	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ADAMTS3 ADAMTS2 MEIS1	3.55e-05	193	43	4	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	facs-Lung-3m-Epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXA1 FOXA2 PLEKHB1 GCLC	3.55e-05	193	43	4	db5e43e0b571737e7006365bdf0575340b8b900b
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ADAMTS3 ADAMTS2 MEIS1	3.63e-05	194	43	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAM12 FOXF2 FOXC1 FOXC2	3.63e-05	194	43	4	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	BOC ADAMTS2 ADAM12 MEIS1	3.63e-05	194	43	4	02b8102be9414d6964cd71019613edff6d88b893
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CACNA1D IRS2 ADAMTS2 MEIS1	3.63e-05	194	43	4	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1D ADAMTS3 ADAMTS2 MEIS1	3.63e-05	194	43	4	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	18-Airway-Epithelial-Secretory_progenitor\|Airway / Age, Tissue, Lineage and Cell class	MMP7 NDRG1 TMC5 FOXA1	3.63e-05	194	43	4	9a2efa50731135a178141aae55fa8b3e022c9904
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 FOXF2 FOXC1 FOXC2	3.63e-05	194	43	4	a7731378f44ca1a229311686caf5740c742d21ba
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXS1 ADAMTS2 FOXC1 FOXC2	3.70e-05	195	43	4	c51b1bee79e77aa2ac444a4883ef533c0095eaad
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FOXS1 ADAMTS2 FOXC1 FOXC2	3.70e-05	195	43	4	43d372373367b71243c6ea958aedccde4478618f
ToppCell	COVID-19-kidney-Fibroblast-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BOC ADAMTS2 ADAM12 MEIS1	3.70e-05	195	43	4	3d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCell	15-Airway-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	NDRG1 TMC5 FOXA1 FOXA2	3.70e-05	195	43	4	cd0af7e260e4f0c5a9ecdfa93619f37b2a9308a5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAM12 FOXF2 FOXC1 FOXC2	3.70e-05	195	43	4	d760d1423f9a8a373fe7b250ea9b1d67a0c0059f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAM12 FOXF2 FOXC1 FOXC2	3.77e-05	196	43	4	cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BOC CACNA1D ADAMTS2 MEIS1	3.77e-05	196	43	4	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Club\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	MMP7 NDRG1 FOXA1 FOXA2	3.77e-05	196	43	4	4e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 FOXF2 FOXC1 FOXC2	3.77e-05	196	43	4	73f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAM12 FOXF2 FOXC1 FOXC2	3.77e-05	196	43	4	44e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXS1 BOC ADAM12 MEIS1	3.85e-05	197	43	4	6668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 FOXF2 FOXC1 FOXC2	3.85e-05	197	43	4	12370ee857fddf1cf26196b23c21b68dcea48eb3
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FOXS1 BOC ADAM12 MEIS1	3.85e-05	197	43	4	7c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FOXS1 ADAM12 FOXF2 FOXC2	3.85e-05	197	43	4	983502a99e6d59bb36225b0246a9990604de1a01
ToppCell	COVID-19-lung-Fibroblast\|lung / Disease (COVID-19 only), tissue and cell type	CACNA1D ADAMTS2 ADAM12 MEIS1	3.93e-05	198	43	4	df3de77216f5c5d6141ec44d01c56b942f611838
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1D ADAMTS2 ADAM12 MEIS1	3.93e-05	198	43	4	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BOC IRS1 MEIS1 FOXF2	3.93e-05	198	43	4	300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MMP7 NDRG1 TMC5 FOXA2	3.93e-05	198	43	4	6712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	BOC CACNA1D ADAMTS2 MEIS1	3.93e-05	198	43	4	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BOC CACNA1D ADAMTS2 MEIS1	3.93e-05	198	43	4	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	MMP7 TMC5 FOXA1 FOXA2	4.00e-05	199	43	4	a8bfc0b93ad9968cf52a25be86995ffe436bd636
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	IRS1 CHD7 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	1.25e-09	176	43	8	981_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	2.39e-08	165	43	7	2835_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	2.71e-08	168	43	7	3395_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	2.82e-08	169	43	7	5572_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.18e-08	172	43	7	3428_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.18e-08	172	43	7	1072_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.31e-08	173	43	7	5336_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.45e-08	174	43	7	1659_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.59e-08	175	43	7	1014_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.59e-08	175	43	7	1058_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.59e-08	175	43	7	7236_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.88e-08	177	43	7	873_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	3.88e-08	177	43	7	1645_DN
Drug	scriptaid; Down 200; 10uM; PC3; HT_HG-U133A	IRS1 MED1 GTF2IRD1 ARID1A FOXA2 CREBBP FOXC1	4.70e-08	182	43	7	6896_DN
Drug	monomethyl phthalate	NCOA3 CHD7 NDRG1 MED1 GTF2IRD1 ARID1A ADAMTS2 CREBBP SUPT5H MYOD1 COX5B FOXC1	1.30e-07	957	43	12	ctd:C517284
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	6.01e-07	163	43	6	5594_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP	6.01e-07	163	43	6	7453_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B AKAP8 GTF2IRD1 ARID1A FOXA2 CREBBP	6.01e-07	163	43	6	7285_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	6.46e-07	165	43	6	5625_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	7.18e-07	168	43	6	6820_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	7.69e-07	170	43	6	7043_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	7.96e-07	171	43	6	1000_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP	7.96e-07	171	43	6	6879_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP FOXC1	8.24e-07	172	43	6	2330_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP FOXC1	8.52e-07	173	43	6	4665_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 MAP7D3 GTF2IRD1 ARID1A CREBBP	8.52e-07	173	43	6	5987_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP	8.81e-07	174	43	6	3462_DN
Drug	HC toxin from Helminthosporium carbonum; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	8.81e-07	174	43	6	909_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	9.11e-07	175	43	6	6891_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	9.42e-07	176	43	6	3312_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP FOXC1	9.42e-07	176	43	6	7499_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A FOXA2 CREBBP	9.42e-07	176	43	6	6546_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A CREBBP FOXC1	9.42e-07	176	43	6	1535_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A FOXC1	9.74e-07	177	43	6	6551_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP	9.74e-07	177	43	6	6434_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	SETD1B MED1 AKAP8 GTF2IRD1 ARID1A CREBBP	9.74e-07	177	43	6	7047_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B GTF2IRD1 ARID1A CREBBP FOXC1	1.01e-06	178	43	6	992_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP FOXC1	1.11e-06	181	43	6	7005_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	IRS1 SETD1B GTF2IRD1 ARID1A CREBBP FOXC1	1.22e-06	184	43	6	6939_DN
Drug	glycyl-dl-alanine	BOC ADAMTS3 ADAMTS2 GCLC	2.02e-06	48	43	4	CID000098153
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A FOXC1	1.29e-05	161	43	5	4768_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CACNA1D IRS1 SETD1B AKAP8 ARID1A	1.45e-05	165	43	5	6085_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.49e-05	166	43	5	7324_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	IRS1 SETD1B GTF2IRD1 ARID1A FOXC1	1.54e-05	167	43	5	5217_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A FOXC1	1.54e-05	167	43	5	3979_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A FOXC1	1.58e-05	168	43	5	3868_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A FOXC1	1.63e-05	169	43	5	5231_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 ARID1A CREBBP FOXC1	1.63e-05	169	43	5	6064_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B AKAP8 ARID1A FOXA2 CREBBP	1.67e-05	170	43	5	3791_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	IRS1 SETD1B AKAP8 ARID1A CREBBP	1.67e-05	170	43	5	1050_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A FOXC1	1.67e-05	170	43	5	5260_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	SETD1B AKAP8 TMC5 ARID1A CREBBP	1.72e-05	171	43	5	1234_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	1.72e-05	171	43	5	4954_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	1.77e-05	172	43	5	7073_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	MED1 AKAP8 ARID1A FOXA2 CREBBP	1.77e-05	172	43	5	6439_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 ARID1A CREBBP FOXC1	1.77e-05	172	43	5	1637_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	1.77e-05	172	43	5	2794_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.77e-05	172	43	5	5903_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A CREBBP	1.82e-05	173	43	5	3243_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP	1.82e-05	173	43	5	4458_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.87e-05	174	43	5	6579_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B AKAP8 TMC5 ARID1A CREBBP	1.87e-05	174	43	5	3993_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A FOXC1	1.87e-05	174	43	5	5945_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A CREBBP	1.87e-05	174	43	5	5693_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.87e-05	174	43	5	5580_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.92e-05	175	43	5	5935_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	IRS1 SETD1B AKAP8 TMC5 FOXC1	1.92e-05	175	43	5	5908_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	1.98e-05	176	43	5	4632_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.98e-05	176	43	5	5976_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	1.98e-05	176	43	5	6980_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B AKAP8 ARID1A FOXA2 CREBBP	2.03e-05	177	43	5	6340_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	2.03e-05	177	43	5	5308_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	2.03e-05	177	43	5	3227_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B GTF2IRD1 ARID1A FOXC1	2.09e-05	178	43	5	1471_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A FOXC1	2.09e-05	178	43	5	4710_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	IRS1 AKAP8 GTF2IRD1 ARID1A CREBBP	2.09e-05	178	43	5	1112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B GTF2IRD1 ARID1A FOXC1	2.09e-05	178	43	5	1672_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	IRS1 SETD1B AKAP8 GTF2IRD1 ARID1A	2.09e-05	178	43	5	6276_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A FOXC1	2.15e-05	179	43	5	6910_DN
Drug	scriptaid; Down 200; 10uM; MCF7; HT_HG-U133A	IRS1 AKAP8 GTF2IRD1 ARID1A FOXC1	2.15e-05	179	43	5	6901_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	CACNA1D IRS1 GTF2IRD1 ARID1A CREBBP	2.20e-05	180	43	5	6454_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B AKAP8 TMC5 ARID1A CREBBP	2.20e-05	180	43	5	3688_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	SETD1B AKAP8 GTF2IRD1 ARID1A CREBBP	2.20e-05	180	43	5	1793_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	IRS1 SETD1B AKAP8 ARID1A CREBBP	2.26e-05	181	43	5	7077_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	IRS1 SETD1B ARID1A CREBBP FOXC1	2.26e-05	181	43	5	6951_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	PLAGL2 IRS1 CHD7 ARID1A CREBBP	2.45e-05	184	43	5	2321_DN
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT_HG-U133A	PLAGL2 IRS2 SETD1B ARID1A FOXA2	2.45e-05	184	43	5	4610_DN
Drug	Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; MCF7; HT_HG-U133A	PLAGL2 IRS1 CHD7 SETD1B ARID1A	2.45e-05	184	43	5	5671_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	SETD1B AKAP8 GTF2IRD1 ARID1A FOXA2	2.45e-05	184	43	5	7555_DN
Drug	1-methyl-4-phenyl-2,3-dihydropyridinium	IRS1 IRS2 COX5B	3.29e-05	33	43	3	ctd:C044755
Drug	Oxolinic acid [14698-29-4]; Up 200; 15.4uM; PC3; HT_HG-U133A	NCOA3 ARID1A FOXA2 ADAM12 MEIS1	3.40e-05	197	43	5	2103_UP
Drug	Tubocurarine chloride pentahydrate (+) [6989-98-6]; Down 200; 5.2uM; PC3; HT_HG-U133A	NCOA3 RAD54L2 ADAM12 MEIS1 ADD1	3.56e-05	199	43	5	6351_DN
Drug	Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT_HG-U133A	NDRG1 TMC5 PLEKHB1 MEIS1 FOXC1	3.56e-05	199	43	5	5302_DN
Drug	hexafluorophosphate	BOC ADAMTS3 ADAMTS2	3.60e-05	34	43	3	CID000009886
Drug	glyphosate	BOC FOXA1 FOXA2 MYOD1 FOXF2	5.15e-05	215	43	5	CID000003496
Drug	butamben	NCOA3 MED1	5.20e-05	6	43	2	ctd:C004605
Drug	Dihydrotestosterone	NCOA3 MMP7 FOXA1 FOXA2 CREBBP MYOD1	5.58e-05	360	43	6	ctd:D013196
Drug	dn B	BOC NCOA3 GCLC	5.90e-05	40	43	3	CID000008331
Drug	Oi-1	ADAMTS3 ADAMTS2	7.27e-05	7	43	2	CID000448053
Drug	glycylvaline	BOC MMP7 MYOD1	9.00e-05	46	43	3	CID000097417
Disease	Prostatic Neoplasms	NCOA3 IRS1 CHD7 NDRG1 ARID1A FOXA1 CREBBP FOXC1	1.79e-06	616	41	8	C0033578
Disease	Malignant neoplasm of prostate	NCOA3 IRS1 CHD7 NDRG1 ARID1A FOXA1 CREBBP FOXC1	1.79e-06	616	41	8	C0376358
Disease	type 2 diabetes mellitus (is_implicated_in)	CACNA1D IRS1 IRS2 FOXA2 FOXC2	3.90e-06	171	41	5	DOID:9352 (is_implicated_in)
Disease	Malignant neoplasm of breast	BOC NCOA3 NDRG1 AKAP8 ARID1A FOXA1 ADAM12 MYOD1 MEIS1	1.33e-05	1074	41	9	C0006142
Disease	Embryonal Rhabdomyosarcoma	ARID1A MYOD1	5.25e-05	8	41	2	C0206656
Disease	nasopharyngeal neoplasm	IRS1 MED1 ADAM12 FOXC1	5.76e-05	151	41	4	EFO_0004252
Disease	amnestic disorder (implicated_via_orthology)	IRS1 IRS2	6.74e-05	9	41	2	DOID:10914 (implicated_via_orthology)
Disease	Liver carcinoma	IRS1 IRS2 MED1 ARID1A DNAJC6 ADD1	6.74e-05	507	41	6	C2239176
Disease	pre-eclampsia (is_marker_for)	ARID1A CREBBP ADD1	7.29e-05	58	41	3	DOID:10591 (is_marker_for)
Disease	lung non-small cell carcinoma (is_marker_for)	MMP7 ARID1A FOXA1 FOXA2	8.91e-05	169	41	4	DOID:3908 (is_marker_for)
Disease	esophagus adenocarcinoma (is_marker_for)	ARID1A FOXA1	1.23e-04	12	41	2	DOID:4914 (is_marker_for)
Disease	free androgen index	CACNA1D CHD7 GTF2IRD1 ARID1A FOXC1	1.64e-04	374	41	5	EFO_0007005
Disease	Tetralogy of Fallot	FOXC1 FOXC2	2.23e-04	16	41	2	C0039685
Disease	neutrophil count, basophil count	CHD7 XKR6 NDRG1 SSBP4	2.63e-04	224	41	4	EFO_0004833, EFO_0005090
Disease	Ischemic stroke, coronary artery disease	BCL9L MMP7 ADAMTS3	2.87e-04	92	41	3	EFO_0001645, HP_0002140
Disease	Congenital hernia of foramen of Morgagni	MYOD1 FOXC2	3.17e-04	19	41	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	MYOD1 FOXC2	3.17e-04	19	41	2	C0265700
Disease	Congenital diaphragmatic hernia	MYOD1 FOXC2	3.89e-04	21	41	2	C0235833
Disease	osteoporosis (biomarker_via_orthology)	IRS1 IRS2	4.28e-04	22	41	2	DOID:11476 (biomarker_via_orthology)
Disease	neutrophil count	CHD7 XKR6 NDRG1 SSBP4 ARID1A LINC00477 CREBBP SUPT5H	5.44e-04	1382	41	8	EFO_0004833
Disease	Cerebral Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0750935
Disease	Intracranial Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0750936
Disease	Pilocytic Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0334583
Disease	Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0004114
Disease	Juvenile Pilocytic Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0280783
Disease	Diffuse Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0280785
Disease	Grade I Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C1704230
Disease	Subependymal Giant Cell Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0205768
Disease	Mixed oligoastrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0547065
Disease	Childhood Cerebral Astrocytoma	NCOA3 NDRG1	5.54e-04	25	41	2	C0338070
Disease	Gemistocytic astrocytoma	NCOA3 NDRG1	5.99e-04	26	41	2	C0334581
Disease	Protoplasmic astrocytoma	NCOA3 NDRG1	5.99e-04	26	41	2	C0334580
Disease	Fibrillary Astrocytoma	NCOA3 NDRG1	5.99e-04	26	41	2	C0334582
Disease	Sezary Syndrome	ARID1A CREBBP	6.47e-04	27	41	2	C0036920
Disease	Anaplastic astrocytoma	NCOA3 NDRG1	6.47e-04	27	41	2	C0334579
Disease	TYPE 2 DIABETES MELLITUS	IRS1 IRS2	6.96e-04	28	41	2	125853
Disease	Type 2 diabetes mellitus	IRS1 IRS2	6.96e-04	28	41	2	cv:C0011860
Disease	glucose metabolism disease (implicated_via_orthology)	IRS1 IRS2	6.96e-04	28	41	2	DOID:4194 (implicated_via_orthology)
Disease	Hyperinsulinism	IRS1 FOXA2	6.96e-04	28	41	2	C0020459
Disease	glycocholate measurement	ADAM12 GCLC	7.99e-04	30	41	2	EFO_0010491
Disease	Breast Carcinoma	NCOA3 NDRG1 ARID1A FOXA1 MEIS1	8.62e-04	538	41	5	C0678222
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	CACNA1D MYOD1	1.15e-03	36	41	2	DOID:11723 (implicated_via_orthology)
Disease	Non-Small Cell Lung Carcinoma	NCOA3 NDRG1 GCLC	1.33e-03	156	41	3	C0007131
Disease	colorectal cancer (is_marker_for)	ARID1A FOXA1 GCLC	1.36e-03	157	41	3	DOID:9256 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AGMYPGTLMSPGGDG	CDX4	11	O14627
MSGTFGGANMPNLYP	ANXA11	61	P50995
GGLAAGAPAMHMASY	AKAP8	66	O43823
GAPAMHMASYGPEPC	AKAP8	71	O43823
GAGMPYPTPAMQGAS	CREBBP	221	Q92793
GGCIMNASTGYPFPM	ADAM12	376	O43184
RGMSIYPGYMSPHAG	RAD54L2	1411	Q9Y4B4
GSAGIPMEVGSYPNM	CHD7	416	Q9P2D1
FGPSGMQGYAPVTGM	ADAMTS2	371	O95450
YGGMDGVGIPSTMYG	MEIS1	11	O00470
ANYPSAGMAGGINPM	ARID1A	821	O14497
PPYSMGGTMANNSAG	ARID1A	946	O14497
GMGHSSDPNAVMYPT	MMP7	221	P09237
MGSTMEPPGGAYLHL	MYADML2	1	A6NDP7
CSDGMMDYSGPPSGA	MYOD1	206	P15172
DGAASFPAGYMYPSM	NDRG1	101	Q92597
GPSGAAAMRSMASGG	COX5B	21	P10606
MIEGTPGQPYGGTMS	GCLC	101	P48506
RAAGSYGGMASPMGV	FOXC2	26	Q99958
YGGMASPMGVYSGHP	FOXC2	31	Q99958
YTEMMPAYPPGGGSG	IRS1	551	P35568
AVAGMPGGSAGAMNS	FOXA1	81	P55317
PGGSAGAMNSMTAAG	FOXA1	86	P55317
GLGPYAAAMNPCMSP	FOXA1	126	P55317
NLGADDGYMPMTPGA	IRS2	646	Q9Y4H2
DGYMPMTPGAALAGS	IRS2	651	Q9Y4H2
FGPAGMQGYAPVTGM	ADAMTS3	361	O15072
MNRGCPSAAVGYPGM	BOC	936	Q9BWV1
AAAGGGYTAMPAPMS	FOXC1	31	Q12948
SPDMEPSYGGGLFDM	DNAJC6	11	O75061
LDSQMGYLPAPGGMA	BCL9L	1481	Q86UU0
MMADGAAAGAGGSPS	MAP7D3	1	Q8IWC1
FGGLVGAMPASMCPA	FOXS1	166	O43638
MPAGSMSTTGYPGVC	KRTAP24-1	1	Q3LI83
SMPGHLPSEDSGYGM	GTF2IRD1	521	Q9UHL9
MYDGIMAYGGPSSSG	CACNA1D	711	Q01668
PGYGMTTGNNPMSGT	MED1	546	Q15648
LDMMPAGYDAGAGAP	FOXF2	246	Q12947
YPGYGSPMPGSLAMG	FOXA2	411	Q9Y261
EPMNSNSMGRPGGDY	NCOA3	931	Q9Y6Q9
MTGQGACPYPPFMAA	SETD1B	786	Q9UPS6
PMYGSGSRTPMYGSQ	SUPT5H	776	O00267
GMYGAHIPTMPSTGV	PLAGL2	296	Q9UPG8
YPAAPQGGMAALNMS	ADD1	106	P35611
AGVLGPSPMGMYSGA	LINC00477	56	Q96M19
PSPMGMYSGASTLTG	LINC00477	61	Q96M19
SRGPPMMGAGYVHGA	XKR6	201	Q5GH73
PCYSAGAPLAMGMLA	PLEKHB1	211	Q9UF11
MASVGPQSYGGGMRP	SSBP4	206	Q9BWG4
MEMANSYGHSLPGAP	TMC5	301	Q6UXY8