Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

SCN10A KCNN3 CATSPER1 CLCN1

3.87e-04182384GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

SCN10A KCNN3 CATSPER1 CLCN1

4.03e-04184384GO:0022832
DomainAdipoR/HlyIII-related

PAQR8 PAQR7

2.08e-0411372IPR004254
DomainHlyIII

PAQR8 PAQR7

2.08e-0411372PF03006
DomainPept_M10A_Zn_BS

MMP8 MMP10

3.95e-0415372IPR021158
DomainHemopexin_CS

MMP8 MMP10

5.10e-0417372IPR018486
DomainPept_M10A_stromelysin-type

MMP8 MMP10

5.73e-0418372IPR016293
DomainPG_binding_1

MMP8 MMP10

7.09e-0420372PF01471
DomainPeptidoglycan-bd-like

MMP8 MMP10

7.09e-0420372IPR002477
DomainHemopexin-like_dom

MMP8 MMP10

9.41e-0423372IPR000585
DomainHemopexin

MMP8 MMP10

9.41e-0423372PF00045
DomainHEMOPEXIN

MMP8 MMP10

9.41e-0423372PS00024
Domain-

MMP8 MMP10

9.41e-04233722.110.10.10
DomainHEMOPEXIN_2

MMP8 MMP10

9.41e-0423372PS51642
DomainHemopexin-like_repeat

MMP8 MMP10

9.41e-0423372IPR018487
DomainHX

MMP8 MMP10

9.41e-0423372SM00120
DomainPept_M10A

MMP8 MMP10

9.41e-0423372IPR021190
DomainM10A_MMP

MMP8 MMP10

9.41e-0423372IPR033739
DomainPeptidase_M10

MMP8 MMP10

1.03e-0324372PF00413
DomainZnMc

MMP8 MMP10

1.50e-0329372SM00235
DomainPeptidase_Metallo

MMP8 MMP10

1.50e-0329372IPR006026
DomainCYSTEINE_SWITCH

MMP8 MMP10

2.98e-0341372PS00546
DomainPept_M10_metallopeptidase

MMP8 MMP10

3.28e-0343372IPR001818
DomainChannel_four-helix_dom

SCN10A CATSPER1

5.69e-0357372IPR027359
Domain-

SCN10A CATSPER1

5.69e-03573721.20.120.350
Domain-

ACAD10 ATP8B4

7.13e-03643723.40.50.1000
DomainIg_2

IGSF9B IL18RAP

9.19e-0373372PF13895
DomainHAD-like_dom

ACAD10 ATP8B4

1.07e-0279372IPR023214
DomainMetalloPept_cat_dom

MMP8 MMP10

1.12e-0281372IPR024079
Domain-

MMP8 MMP10

1.12e-02813723.40.390.10
PathwayWP_CHRONIC_HYPERGLYCEMIA_IMPAIRMENT_OF_NEURON_FUNCTION

SCN10A MMP8 MMP10

1.12e-0446293M46450
PathwayKEGG_MEDICUS_REFERENCE_MEMBRANE_INITIATED_PROGESTERONE_SIGNALING_PATHWAY

PAQR8 PAQR7

1.46e-049292M47802
Pubmed

Progesterone-facilitated lordosis of estradiol-primed mice is attenuated by knocking down expression of membrane progestin receptors in the midbrain.

PAQR8 PAQR7

1.16e-06238224269738
Pubmed

The roles of MMP8/MMP10 polymorphisms in ischemic stroke susceptibility.

MMP8 MMP10

1.16e-06238236282475
Pubmed

The further redefining of steroid-mediated signaling.

PAQR8 PAQR7

1.16e-06238212606724
Pubmed

Matrix metalloproteinases, tumor necrosis factor and multiple sclerosis: an overview.

MMP8 MMP10

1.16e-0623829042108
Pubmed

Expression of membrane progesterone receptors (mPR/PAQR) in ovarian cancer cells: implications for progesterone-induced signaling events.

PAQR8 PAQR7

3.48e-06338221761364
Pubmed

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes.

PAQR8 PAQR7

3.48e-06338212574519
Pubmed

Identification, classification, and partial characterization of genes in humans and other vertebrates homologous to a fish membrane progestin receptor.

PAQR8 PAQR7

3.48e-06338212601167
Pubmed

Genetic variations in matrix metalloproteinases may be associated with increased risk of ulcerative colitis.

MMP8 MMP10

6.96e-06438221925226
Pubmed

Activation of the precursor of human stromelysin 2 and its interactions with other matrix metalloproteinases.

MMP8 MMP10

6.96e-0643829578462
Pubmed

Heterologous expression of human mPRalpha, mPRbeta and mPRgamma in yeast confirms their ability to function as membrane progesterone receptors.

PAQR8 PAQR7

1.16e-05538218603275
Pubmed

Fine physical mapping of the human matrix metalloproteinase genes clustered on chromosome 11q22.3.

MMP8 MMP10

2.43e-0573828921407
Pubmed

Identification and enzymatic characterization of two diverging murine counterparts of human interstitial collagenase (MMP-1) expressed at sites of embryo implantation.

MMP8 MMP10

2.43e-05738211113146
Pubmed

BRCA2 mediates centrosome cohesion via an interaction with cytoplasmic dynein.

MMP10 MFSD13A F8

3.38e-055738327433848
Pubmed

Discovering human diabetes-risk gene function with genetics and physiological assays.

DGKB ADRA2A

4.16e-05938230242153
Pubmed

Brevican is degraded by matrix metalloproteinases and aggrecanase-1 (ADAMTS4) at different sites.

MMP8 MMP10

4.16e-05938210986281
Pubmed

PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif.

PAQR8 PAQR7

6.35e-051138216044242
Pubmed

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

KCNN3 MMP8 MMP10 MFSD13A

6.85e-0520138423535732
Pubmed

Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.

DGKB ADRA2A

7.62e-051238220419449
Pubmed

Metalloproteinases promote plaque rupture and myocardial infarction: A persuasive concept waiting for clinical translation.

MMP8 MMP10

1.05e-041438225636537
Pubmed

Association of matrix metalloproteinase gene polymorphisms with refractive error in Amish and Ashkenazi families.

MMP8 MMP10

1.38e-041638220484597
Pubmed

Matrix metalloproteinases in tumor invasion.

MMP8 MMP10

1.38e-041638210949577
Pubmed

Expression dynamics of metalloproteinases during mandibular bone formation: association with Myb transcription factor.

MMP8 MMP10

1.38e-041638237701782
Pubmed

Expression analysis of the entire MMP and TIMP gene families during mouse tissue development.

MMP8 MMP10

1.96e-041938215063736
Pubmed

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.

DGKB ADRA2A

2.18e-042038220081858
Pubmed

Matrix metalloproteinases.

MMP8 MMP10

2.65e-042238210419448
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP8 MMP10

2.65e-042238223421805
Pubmed

Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.

MMP8 MMP10

3.16e-042438215734845
Pubmed

Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.

KCNN3 KIF3B IL18RAP USP6NL

3.38e-0430538421244100
Pubmed

Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing.

MMP8 IL18RAP

3.43e-042538219180518
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

SCN10A KCNN3 CLCN1

4.76e-0413938316985003
Pubmed

Analysis of mouse embryonic patterning and morphogenesis by forward genetics.

NUP133 SMO

6.01e-043338215755804
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

MMP8 MMP10

7.15e-043638220587546
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

SCN10A BLMH MAL2 SMO KIF3B CPVL

7.60e-04101638619056867
Pubmed

EpCAM Is Essential to Maintaining the Immune Homeostasis of Intestines via Keeping the Expression of pIgR in the Intestinal Epithelium of Mice.

MMP8 MMP10

1.07e-034438235493520
Cytoband11q22.3

MMP8 MMP10

6.17e-044438211q22.3
CytobandEnsembl 112 genes in cytogenetic band chr11q22

MMP8 MMP10

3.58e-03107382chr11q22
GeneFamilyProgestin and adipoQ receptor family

PAQR8 PAQR7

1.09e-0411262930
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP8 MMP10

5.38e-0424262891
ToppCellcontrol-immature_Neutrophil|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC4A10 IGSF9B VIPAS39 TMEM186 CPVL

5.56e-07189385bdfd120900ba58d5e54765f7b576e1f8cc2401bf
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAQR8 MMP8 IL18RAP PAQR7

8.67e-061533846a2a2379238133ce0ad714af130ffe02dd317247
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAQR8 MMP8 IL18RAP PAQR7

8.67e-06153384faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-NK_CD56bright|Multiple_Sclerosis / Disease, Lineage and Cell Type

FMN2 ATP8B4 PPP1R36 IL18RAP

1.11e-0516338482c4b25f05bd404fdee9aa90f23efd6dffc04e7b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF9B ADRA2A F8 GPR151

1.44e-05174384f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell3'-GW_trimst-1-LargeIntestine-Hematopoietic-T_cells-ILCP|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC4A10 IGSF9B ATP8B4 IL18RAP

1.61e-05179384dd3cf8fd10dc257d933a7f45860dc2e244c158b7
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAQR8 MAL2 ADRA2A CLCN1

1.64e-051803847c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAQR8 ADRA2A CLCN1 MMP10

1.83e-05185384c3d1a312569f3d619f7295812741cbf068ec6c1f
ToppCellLPS-IL1RA-Myeloid-Myeloid_granulocytic-Neutrophils|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF9B MMP8 MMP10

1.39e-041183836053e19d040fb394f9c270361af07b0c5a4d47db
ToppCellLPS-IL1RA-Myeloid-Myeloid_granulocytic|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IGSF9B MMP8 MMP10

1.39e-04118383811e8521129914eef46785a4227c1860e77d9096
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Crh|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SCN10A KCNN3 ADRA2A

2.11e-0413638344f03e4f55fb2c5f8b9397142c89f7194b009cc6
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC4A10 DGKB FMN2

2.25e-04139383a1945b07f177cde40e7eea03a19236ce76165857
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC4A10 DGKB FMN2

2.70e-04148383d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCell3'_v3-blood-Lymphocytic_Invariant-Inducer-like|blood / Manually curated celltypes from each tissue

SLC4A10 DGKB LYPD6B

2.76e-0414938375422e1a22736375e9ef439db0b2a5efa3f653a3
ToppCellChildren_(3_yrs)-Immune-mast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC4A10 CATSPER1 IL18RAP

2.98e-04153383d3fb83ca984c7583b1e51c364be6c7c17f67b048
ToppCellDendritic_Cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SCN10A ATP8B4 CPVL

3.04e-0415438365013f696da623d37f1e3447a294dfb3c31ae93b
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LYPD6B ADRA2A ATP8B4

3.10e-041553838dab23aad905cc35a35643baa0554acb3f6fe6c8
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 IL18RAP PAQR7

3.10e-041553831fb49b48e34e740118908951e079ea2a9994ae4f
ToppCell367C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LYPD6B ADRA2A ATP8B4

3.10e-0415538342533beaded07068f00540de704de07e4f19abcf
ToppCellE16.5-Immune-Immune_Myeloid-Granulocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAQR8 MMP8 IL18RAP

3.10e-04155383c648512305166d2a2f0e284c127bc802af908071
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 IL18RAP PAQR7

3.10e-041553834ae91bc7dbb9f713a1f110c17834b1d89f1b28db
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ATP8B4 IL18RAP PAQR7

3.10e-04155383fdcc8a475156329b3594d5ed22ba03538305327c
ToppCellfacs-Lung-Endomucin_-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6B ATP8B4 MMP8

3.21e-041573832b60de520edf167f5ca790b478557a778435b3d9
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAQR8 ZSWIM9 TMEM186

3.21e-04157383bd45590da540a557dc8096980a45220fccb99505
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Mes-Epi-like-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAQR8 ZSWIM9 TMEM186

3.21e-0415738300c9a58b033b8b95b0d838f233dd077b62d8b02a
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAL2 LYPD6B PPP1R36

3.21e-0415738310989c7046fc859f137c7cef3296508d4476f11f
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Myeloid-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6B MMP8 IL18RAP

3.34e-04159383a6093b230afdd4d91870d289c6ac91d1856666a3
ToppCellcontrol-NK_CD56bright|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

ZSWIM9 ATP8B4 IL18RAP

3.40e-04160383f49c810072604c4dee51025073c9e088c00daf4a
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 ATP8B4 IL18RAP

3.40e-04160383398f162e8a75c6cb5c3e4d1832e98d386e1f222b
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-CD45____NK_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAQR8 ATP8B4 IL18RAP

3.40e-0416038312aaab0291035f578e2433efd169ae72f393a5a5
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6B ATP8B4 MMP8

3.46e-04161383e227f7b711475624cf80e77f235b1783d88d57b4
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6B ATP8B4 MMP8

3.46e-041613838280a029026c272cae9649b27575831b0dd4e242
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

ADRA2A CATSPER1 IL18RAP

3.52e-04162383e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCellCOVID-CD8-memory_CD4|COVID / Condition, Cell_class and T cell subcluster

SLC4A10 KIF3B IL18RAP

3.52e-0416238322b2a32217d357146c117e618813d451510a1801
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LYPD6B ATP8B4 MMP8

3.65e-041643838e6dbddacd56a07769163813e3ebfad13302bb62
ToppCell10x5'-blood-Lymphocytic_NK-NK_CD56bright_CD16-|blood / Manually curated celltypes from each tissue

SMO ATP8B4 IL18RAP

3.78e-04166383ba42349a68b22e91a0340bda1ccecd6c7592392f
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

SMO CLCN1 CPVL

3.78e-041663839f14e3ef19d5903278c040be1c477501237173fa
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC4A10 DGKB FMN2

3.85e-04167383c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DGKB MAL2 CPVL

3.85e-041673839f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LYPD6B ADRA2A CLCN1

3.85e-041673837cb5b52aaa5b595fe2e97d9e175294ea8d63b165
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c07-TYROBP|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

BLMH CATSPER1 IL18RAP

3.85e-04167383ded4d6cccd3660662f12cf5a512de31d26325f1b
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 USP6NL GPR151

3.85e-04167383961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 USP6NL GPR151

3.85e-041673833760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DGKB MAL2 CPVL

3.85e-04167383bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

DGKB SMO IGSF9B

3.85e-04167383c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellfacs-Tongue-nan-3m-Epithelial-basal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IGSF9B MMP8 MMP10

3.92e-04168383ca0c4a819f9047fc40d224f7656fec60f6fa05d8
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADRA2A ATP8B4 IL18RAP

3.92e-0416838393b7138f17aa14a6398c9b4ea7237781a0e19a66
ToppCellE18.5-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADRA2A ATP8B4 IL18RAP

3.92e-04168383e393553208617a023f1646169c892a87c95db3f5
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC-DC1|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PAQR8 SMO CPVL

3.99e-04169383319511ea57bbd72c2d95e8516d093689df67a912
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

SMO CLCN1 CPVL

3.99e-04169383a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 MAL2 IGSF9B

4.06e-04170383833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 MFSD13A PAQR7

4.13e-04171383fea6ef6bbfebea2dd0f0360c7db7a5e858f15958
ToppCellCOVID-19_Severe-NK_CD56bright|COVID-19_Severe / Disease condition and Cell class

ATP8B4 CATSPER1 IL18RAP

4.13e-041713835810f790012a0750ca3378595514f66a99f123be
ToppCellHealthy/Control-NK_CD56bright|World / Disease group and Cell class

SLC4A10 ATP8B4 IL18RAP

4.13e-0417138379d7efefdae267905af05f3001514b8b6934d86e
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 MFSD13A PAQR7

4.13e-04171383f15594fd4d709920733de9376a391dedc62b65de
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LYPD6B ADRA2A CLCN1

4.27e-04173383b75353fcbc9f8cdb21d4f10ddbc93a83fd797a3c
ToppCellCOVID-19_Moderate-NK_CD56bright|COVID-19_Moderate / disease group, cell group and cell class

ATP8B4 CATSPER1 IL18RAP

4.27e-04173383a07dcb1e555caaa2235aec219334fcbf2d07f10c
ToppCellHealthy/Control-NK_CD56bright|Healthy/Control / Disease group and Cell class

SLC4A10 ATP8B4 IL18RAP

4.34e-04174383f53f675c8cb14294ac526dcc3dca4f08288f8473
ToppCellInt-URO-Lymphocyte-T_NK-MAIT|Int-URO / Disease, Lineage and Cell Type

SLC4A10 IGSF9B IL18RAP

4.34e-041743835227ed29f5f0d3e0aaa7f3cfd362f96d3e2660f7
ToppCell3'_v3-bone_marrow-Lymphocytic_B_plasma-Plasma_cells|bone_marrow / Manually curated celltypes from each tissue

KCNN3 CLPTM1L LYPD6B

4.41e-0417538351301f3f44d3e88397f367cedd1e2abaa2be4c6f
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Dendritic-conventional_dendritic_cell-DC_c1-CLEC9A|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SMO CLCN1 CPVL

4.56e-04177383e68ad19963a3d8917dfdb81127a41c4fcbe61dd5
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAL2 ZSWIM9 PPP1R36

4.56e-04177383092a345cb802f183322aa5542341ba2d96d4f06a
ToppCelldroplet-Lung-LUNG-30m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAL2 ZSWIM9 PPP1R36

4.56e-041773837ac99ff16df94b4e08d361e3d98a7b3af8d6ee3b
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADRA2A F8 GPR151

4.64e-04178383fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellfacs-Diaphragm-Limb_Muscle-18m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 MMP8 MFSD13A

4.64e-0417838340bd605b801d9ae76cffc8f62836092fc2b06812
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

KCNN3 LYPD6B F8

4.72e-041793831ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCellCOVID-19_Mild-NK_CD56bright|COVID-19_Mild / Disease condition and Cell class

ATP8B4 CATSPER1 IL18RAP

4.72e-0417938390e7a4af195aa2332b07a9f06cde63e72ff49255
ToppCellmild_COVID-19-NK_CD56bright|mild_COVID-19 / disease group, cell group and cell class (v2)

DGKB ATP8B4 IL18RAP

4.79e-04180383d8b418edd807a51c0b5f4018b8b478dcc65892a7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LYPD6B ADRA2A CLCN1

4.87e-041813831d3d1b5a6efe9cedd03b7e0b5684df97f0246729
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LYPD6B ADRA2A CLCN1

4.87e-041813830069e8308de932df43660bbe926637c57b8bf7f6
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNN3 F8 GPR151

4.95e-041823830cde2775bdaaa2172499925bd59b0ac2d545eb27
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNN3 F8 GPR151

4.95e-041823832cc434e46985c66fc36de05344a67aa96d90abc9
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 ADRA2A USP6NL

4.95e-04182383be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B4 CATSPER1 IL18RAP

4.95e-04182383feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCellfacs-Lung-Endomucin-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 ADRA2A USP6NL

4.95e-0418238374dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCellfacs-Lung-24m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNN3 F8 GPR151

4.95e-041823833e7457b2a70b45735fb75d6617b7f34cef28758e
ToppCellcellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic-cDC2|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATP8B4 CATSPER1 CPVL

5.03e-041833839840706f972387241bf1d4ba8af25efc3214a91b
ToppCellcellseq2-Immune-Immune_Myeloid-Myeloid_Dendritic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ATP8B4 CATSPER1 CPVL

5.03e-04183383409cb52cf4c967e52bf75a6680bcbe87f638c75d
ToppCellmild_COVID-19-NK_CD56bright|World / disease group, cell group and cell class (v2)

DGKB ATP8B4 IL18RAP

5.03e-041833839a4899afac0f91203209392c5f67b3d0aa356b86
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 PPP1R36 F8

5.03e-04183383919c9861073d12fd12aecd7469b1478b13838c43
ToppCellB_cell_maturation-plasma|World / Lineage and Cell class

KCNN3 CLPTM1L LYPD6B

5.03e-041833830c3cb61912df05f1beba1004540770ef1a4de786
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAL2 ADRA2A CLCN1

5.03e-04183383263937906ddabc798bbe60f0da28ba859a5c72e2
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SLC4A10 ATP8B4 IL18RAP

5.11e-041843833e9d75af578297950e469f23fb2d28393a2feef8
ToppCelllymphoid-NK_cell-TNFRSF18+IL7R-_NK_cell|lymphoid / Lineage, cell class and subclass

ATP8B4 CATSPER1 IL18RAP

5.11e-0418438362a3918705a3fcf3ef25c9ceb80f575a2e56ef76
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

SMO CLCN1 CPVL

5.11e-04184383ee295f6fa898da53883e1358b17f2c2dd177e9a7
ToppCell3'_v3-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

SMO CLCN1 CPVL

5.11e-041843838e393eea7240584a3cef718bee094e2705ec1891
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 MFSD13A PAQR7

5.11e-04184383185b49630da61cbf45c0926d1b992943296d2a54
ToppCell10x5'-GI_small-bowel-Myeloid_Dendritic-DC1|GI_small-bowel / Manually curated celltypes from each tissue

SMO LYPD6B CPVL

5.19e-0418538323ffba9216729b5bdb30b35742ba2627bb1200bf
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNN3 ACAD10 F8

5.19e-04185383bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MAL2 LYPD6B ADRA2A

5.27e-041863836d8dd6d0403d149cb6edb346581fe6c248036785
ToppCellmild-unassigned|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NUP133 GTF2H1 TMEM186

5.27e-041863835b2e1a58916f392fa1156bf9210df528775248ff
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-innate_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ATP8B4 CATSPER1 IL18RAP

5.27e-04186383c984e5729958237b101df96d1c89a236faacded6
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKB SMO VIPAS39

5.36e-04187383f1e9877d859369b862d4a559ec9ab9be74a67a96
ToppCellfacs-Heart-LA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DGKB SMO VIPAS39

5.36e-041873833ffbd50b49059dcd3e23c5ac01901e4352142446
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 MFSD13A PAQR7

5.36e-04187383e53471c3e146a6f54788d81ecc469aba55b051bb
ToppCell18-Airway-Epithelial-Club-like_secretory|Airway / Age, Tissue, Lineage and Cell class

MAL2 LYPD6B MMP10

5.36e-04187383d1e301afcc39054ae1f867d80e564e30a137e3f8
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Lymphocytic-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B4 MFSD13A PAQR7

5.36e-041873833d7d51fbadb20dc884d0b3c0d61b80f022b19d09
ToppCellHealthy_donor-NK_CD56bright|World / disease group, cell group and cell class (v2)

SLC4A10 ATP8B4 IL18RAP

5.44e-041883838ee359199c61c3b5b498ac35148390db5cc1a836
ToppCellHealthy_donor-NK_CD56bright|Healthy_donor / disease group, cell group and cell class (v2)

SLC4A10 ATP8B4 IL18RAP

5.52e-041893839eac380a3bb4b685effb52d816e1960972660646
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KCNN3 CLPTM1L LYPD6B

5.52e-041893835a42be62552d912d0abf68f00d75ac80bbd69f2c
Diseasestromelysin-2 measurement

MMP8 MMP10

2.41e-056382EFO_0802095
Diseasematrix metalloproteinase 10 measurement

MMP8 MMP10

3.38e-057382EFO_0010589
Diseaselongitudinal alcohol consumption measurement

IGSF9B ADRA2A

5.78e-059382EFO_0007645
Diseasesusceptibility to plantar warts measurement

DGKB CLPTM1L USP6NL

2.14e-0490383EFO_0008406
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

DGKB ADRA2A

4.75e-0425382EFO_0004465, EFO_0004466, EFO_0004469
DiseasePigmented Basal Cell Carcinoma

CLPTM1L SMO

5.98e-0428382C1368275
DiseaseCarcinoma, Basal Cell

CLPTM1L SMO

6.41e-0429382C4721806
DiseaseParoxysmal atrial fibrillation

SCN10A KCNN3 DGKB

1.07e-03156383C0235480
DiseasePersistent atrial fibrillation

SCN10A KCNN3 DGKB

1.07e-03156383C2585653
Diseasefamilial atrial fibrillation

SCN10A KCNN3 DGKB

1.07e-03156383C3468561
DiseaseAtrial Fibrillation

SCN10A KCNN3 DGKB

1.15e-03160383C0004238
Diseaseatrial fibrillation

SCN10A KCNN3 DGKB ACAD10

1.30e-03371384EFO_0000275
Diseasehuman papilloma virus infection, oral cavity cancer

CLPTM1L ATP8B4

1.35e-0342382EFO_0001668, EFO_0005570
Diseasechronic obstructive pulmonary disease

PAQR8 DGKB ACAD10 ATP8B4 KIF3B

1.80e-03688385EFO_0000341
Diseasefish consumption measurement

DGKB ACAD10

3.10e-0364382EFO_0010139
DiseaseAlzheimer disease

KCNN3 FMN2 ATP8B4 CATSPER1

3.42e-03485384MONDO_0004975
DiseaseContact hypersensitivity

MMP8 MMP10

3.79e-0371382C0162351

Protein segments in the cluster

PeptideGeneStartEntry
YFFDFWNNLDFFIMA

CATSPER1

506

Q8NEC5
NWNFYMAFSFFRVAA

ACAD10

546

Q6JQN1
FFYKNFAFTLVHFWF

ATP8B4

876

Q8TF62
WSFICYFFFQNLDFS

AADACL3

246

Q5VUY0
YFFFQNLDFSSSWQE

AADACL3

251

Q5VUY0
KTYFFVNDQFWRYDN

MMP8

386

P22894
FFAADKYWRFDENSQ

MMP10

401

P09238
QFADQNFSDFLFRWY

NUP133

891

Q8WUM0
LLQAKSEFWHYSFFF

PAQR7

126

Q86WK9
KDFDAFVSYAKWSSF

IL18RAP

406

O95256
NKTYNSNLFFWFFPA

CPVL

81

Q9H3G5
EYKFFWTARLAFSYT

KCNN3

381

Q9UGI6
ALFFTIFDETKSWYF

F8

1896

P00451
FFASFYFWRAYDQCK

GPR151

216

Q8TDV0
WANKFRFSTDYEFLD

METTL21C

221

Q5VZV1
AHFFYSSDQAWYDRF

PAQR8

161

Q8TEZ7
NKFWYFEFGTSETFS

DGKB

616

Q9Y6T7
NIEEFEFSQSYLFFW

BLMH

91

Q13867
ANWNFLDFAYHFTVF

MAL2

96

Q969L2
EFVQWFKKFFDANYD

MAPRE1

106

Q15691
FFSIWHEFSSDFKDF

FMN2

1661

Q9NZ56
SVFASYAFWNKEDFS

MFSD13A

176

Q14CX5
YAFWNKEDFSSFRAF

MFSD13A

181

Q14CX5
TLFKFFFWFGYCNSS

ADRA2A

421

P08913
WKAFTYKAFNTFIDD

CLPTM1L

466

Q96KA5
NYWRGFFAATFSAFV

CLCN1

301

P35523
TEKEFWTRFFQSHYF

GTF2H1

216

P32780
SFYTMKWFFQCFLDR

USP6NL

261

Q92738
ERAFFSWAEFSRFFD

ZSWIM9

21

Q86XI8
FFAKDLSQDTWYEFR

IGSF9B

671

Q9UPX0
FDSFTSNWQDALFAY

SLC35B2

281

Q8TB61
TFTFDAVYDWNAKQF

KIF3B

56

O15066
YTSFDSFAWAFLSLF

SCN10A

336

Q9Y5Y9
YFWSDFRDAFSLQCL

SLC4A10

496

Q6U841
FNIQDKNSSYFADWF

TUBB8B

331

A6NNZ2
FWMFYRFDAIRTFGF

TMEM186

56

Q96B77
KDWKFFESFYTFCTY

PPP1R36

231

Q96LQ0
YWNSSKFKAFTFDDE

VIPAS39

11

Q9H9C1
FYDFFNQAEWERSFR

SMO

471

Q99835
IFSESWAFAKNINFY

LYPD6B

31

Q8NI32