Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	KIF26B KIF21A KIF4A KIF3A KIF4B DNAH8 DNAH9	4.20e-07	70	133	7	GO:0003777
GeneOntologyMolecularFunction	cytoskeletal motor activity	KIF26B MYO1H KIF21A KIF4A KIF3A KIF4B DNAH8 DNAH9	1.24e-06	118	133	8	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	PMS2P1 DDX12P HYOU1 ABCA13 KIF26B MYO1H KIF21A KIF4A KIF3A KIF4B ASCC3 DNAH8 DNAH9 HSPA14 DDX11L8	1.49e-05	614	133	15	GO:0140657
GeneOntologyMolecularFunction	SUMO binding	SIMC1 HERC2 USPL1	2.59e-04	19	133	3	GO:0032183
GeneOntologyMolecularFunction	triplex DNA binding	DDX12P DDX11L8	2.62e-04	4	133	2	GO:0045142
GeneOntologyMolecularFunction	histone H3K36 trimethyltransferase activity	NSD2 PRDM9	4.35e-04	5	133	2	GO:0140955
GeneOntologyMolecularFunction	ATP hydrolysis activity	PMS2P1 DDX12P ABCA13 KIF21A KIF3A ASCC3 DNAH8 DNAH9 HSPA14 DDX11L8	7.51e-04	441	133	10	GO:0016887
GeneOntologyCellularComponent	septin complex	SEPTIN2 SEPTIN1 SEPTIN7	9.30e-05	14	136	3	GO:0031105
GeneOntologyCellularComponent	septin ring	SEPTIN2 SEPTIN1 SEPTIN7	9.30e-05	14	136	3	GO:0005940
GeneOntologyCellularComponent	midbody	DDX12P KIF4A SEPTIN2 ANLN SEPTIN1 KIF4B SEPTIN7 DDX11L8	1.05e-04	222	136	8	GO:0030496
GeneOntologyCellularComponent	septin cytoskeleton	SEPTIN2 SEPTIN1 SEPTIN7	1.42e-04	16	136	3	GO:0032156
GeneOntologyCellularComponent	microtubule associated complex	KIF21A KIF4A KIF3A KIF4B DNAH8 DNAH9	6.55e-04	161	136	6	GO:0005875
Domain	Kinesin-like_fam	KIF26B KIF21A KIF4A KIF3A KIF4B	9.73e-06	43	125	5	IPR027640
Domain	-	KIF26B KIF21A KIF4A KIF3A KIF4B	1.09e-05	44	125	5	3.40.850.10
Domain	Kinesin	KIF26B KIF21A KIF4A KIF3A KIF4B	1.09e-05	44	125	5	PF00225
Domain	KISc	KIF26B KIF21A KIF4A KIF3A KIF4B	1.09e-05	44	125	5	SM00129
Domain	KINESIN_MOTOR_1	KIF26B KIF21A KIF4A KIF3A KIF4B	1.09e-05	44	125	5	PS00411
Domain	Kinesin_motor_dom	KIF26B KIF21A KIF4A KIF3A KIF4B	1.09e-05	44	125	5	IPR001752
Domain	KINESIN_MOTOR_2	KIF26B KIF21A KIF4A KIF3A KIF4B	1.09e-05	44	125	5	PS50067
Domain	BEACH	WDR81 LYST WDFY3	2.39e-05	9	125	3	PS50197
Domain	Beach	WDR81 LYST WDFY3	2.39e-05	9	125	3	PF02138
Domain	-	WDR81 LYST WDFY3	2.39e-05	9	125	3	1.10.1540.10
Domain	Beach	WDR81 LYST WDFY3	2.39e-05	9	125	3	SM01026
Domain	BEACH_dom	WDR81 LYST WDFY3	2.39e-05	9	125	3	IPR000409
Domain	Asp/Glu/Uridylate_kinase	NAGS ALDH18A1	4.44e-05	2	125	2	IPR001048
Domain	-	NAGS ALDH18A1	4.44e-05	2	125	2	3.40.1160.10
Domain	G_SEPTIN_dom	SEPTIN2 SEPTIN1 SEPTIN7	7.97e-05	13	125	3	IPR030379
Domain	Septin	SEPTIN2 SEPTIN1 SEPTIN7	7.97e-05	13	125	3	PF00735
Domain	G_SEPTIN	SEPTIN2 SEPTIN1 SEPTIN7	7.97e-05	13	125	3	PS51719
Domain	Septin	SEPTIN2 SEPTIN1 SEPTIN7	1.01e-04	14	125	3	IPR016491
Domain	Lsm14_N	EDC3 LSM14A	1.33e-04	3	125	2	IPR025609
Domain	LSM14	EDC3 LSM14A	1.33e-04	3	125	2	SM01271
Domain	DFDF	EDC3 LSM14A	1.33e-04	3	125	2	IPR025762
Domain	LSM14	EDC3 LSM14A	1.33e-04	3	125	2	PF12701
Domain	FDF	EDC3 LSM14A	1.33e-04	3	125	2	PF09532
Domain	FDF_dom	EDC3 LSM14A	1.33e-04	3	125	2	IPR019050
Domain	FDF	EDC3 LSM14A	1.33e-04	3	125	2	SM01199
Domain	DFDF	EDC3 LSM14A	1.33e-04	3	125	2	PS51512
Domain	Kinesin_motor_CS	KIF21A KIF4A KIF3A KIF4B	1.60e-04	41	125	4	IPR019821
Domain	SHR-BD	VPS13C VPS13B	2.64e-04	4	125	2	IPR009543
Domain	VPS13_C	VPS13C VPS13B	2.64e-04	4	125	2	PF16909
Domain	VPS13_C	VPS13C VPS13B	2.64e-04	4	125	2	IPR031645
Domain	SHR-BD	VPS13C VPS13B	2.64e-04	4	125	2	PF06650
Domain	Autophagy-rel_C	VPS13C VPS13B	4.39e-04	5	125	2	IPR015412
Domain	ATG_C	VPS13C VPS13B	4.39e-04	5	125	2	PF09333
Domain	-	LAMA2 ADGRV1 NRXN3 WDFY3 ADGRD1	4.44e-04	95	125	5	2.60.120.200
Domain	ZF_PHD_2	NSD2 ZMYND8 KMT2A ASXL2 KAT6B	4.44e-04	95	125	5	PS50016
Domain	ARM-type_fold	DOCK8 APOB ECPAS LYST EIF4G2 TTI1 WDFY3 NIPBL GPRASP2	4.65e-04	339	125	9	IPR016024
Domain	ZF_PHD_1	NSD2 ZMYND8 KMT2A ASXL2 KAT6B	4.66e-04	96	125	5	PS01359
Domain	Znf_FYVE_PHD	ZFYVE16 NSD2 ZMYND8 KMT2A WDFY3 KAT6B	4.67e-04	147	125	6	IPR011011
Domain	PH_BEACH	LYST WDFY3	6.55e-04	6	125	2	PF14844
Domain	Chorein_N	VPS13C VPS13B	1.21e-03	8	125	2	PF12624
Domain	DHC_N1	DNAH8 DNAH9	1.21e-03	8	125	2	PF08385
Domain	PH-BEACH_dom	LYST WDFY3	1.21e-03	8	125	2	IPR023362
Domain	VPS13_N	VPS13C VPS13B	1.21e-03	8	125	2	IPR026854
Domain	-	LYST WDFY3	1.21e-03	8	125	2	2.30.29.40
Domain	PH_BEACH	LYST WDFY3	1.21e-03	8	125	2	PS51783
Domain	Dynein_heavy_dom-1	DNAH8 DNAH9	1.21e-03	8	125	2	IPR013594
Domain	GPS	ADGRV1 PKDREJ ADGRD1	1.50e-03	34	125	3	SM00303
Domain	PHD	NSD2 ZMYND8 KMT2A KAT6B	1.61e-03	75	125	4	PF00628
Domain	P-loop_NTPase	ABCA13 KIF26B NOA1 KIF21A KIF4A KIF3A SEPTIN2 SEPTIN1 KIF4B ASCC3 SEPTIN7 DNAH8 DNAH9 NLRP13	1.62e-03	848	125	14	IPR027417
Domain	GPS	ADGRV1 PKDREJ ADGRD1	1.93e-03	37	125	3	IPR000203
Domain	Znf_PHD-finger	NSD2 ZMYND8 KMT2A KAT6B	1.95e-03	79	125	4	IPR019787
Domain	SET	NSD2 PRDM9 KMT2A	2.59e-03	41	125	3	PF00856
Domain	-	HYOU1 HSPA14	2.81e-03	12	125	2	2.60.34.10
Domain	HSP70_peptide-bd	HYOU1 HSPA14	2.81e-03	12	125	2	IPR029047
Domain	PHD	NSD2 ZMYND8 KMT2A KAT6B	3.01e-03	89	125	4	SM00249
Domain	-	ZFYVE16 RBBP6 NSD2 RC3H1 ZMYND8 TRIM69 KMT2A WDFY3 KAT6B	3.24e-03	449	125	9	3.30.40.10
Domain	Znf_PHD	NSD2 ZMYND8 KMT2A KAT6B	3.26e-03	91	125	4	IPR001965
Domain	Heat_shock_70_CS	HYOU1 HSPA14	3.30e-03	13	125	2	IPR018181
Domain	ConA-like_dom	LAMA2 ADGRV1 TRIM69 NRXN3 WDFY3 ADGRD1	3.58e-03	219	125	6	IPR013320
Domain	SET	NSD2 PRDM9 KMT2A	3.60e-03	46	125	3	SM00317
Domain	Znf_RING/FYVE/PHD	ZFYVE16 RBBP6 NSD2 RC3H1 ZMYND8 TRIM69 KMT2A WDFY3 KAT6B	3.75e-03	459	125	9	IPR013083
Domain	Dynein_heavy_chain_D4_dom	DNAH8 DNAH9	3.84e-03	14	125	2	IPR024317
Domain	Dynein_HC_stalk	DNAH8 DNAH9	3.84e-03	14	125	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH8 DNAH9	3.84e-03	14	125	2	IPR013602
Domain	DHC_N2	DNAH8 DNAH9	3.84e-03	14	125	2	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH8 DNAH9	3.84e-03	14	125	2	IPR011704
Domain	MT	DNAH8 DNAH9	3.84e-03	14	125	2	PF12777
Domain	AAA_8	DNAH8 DNAH9	3.84e-03	14	125	2	PF12780
Domain	AAA_5	DNAH8 DNAH9	3.84e-03	14	125	2	PF07728
Domain	DHC_fam	DNAH8 DNAH9	4.41e-03	15	125	2	IPR026983
Domain	Dynein_heavy	DNAH8 DNAH9	4.41e-03	15	125	2	PF03028
Domain	Dynein_heavy_dom	DNAH8 DNAH9	4.41e-03	15	125	2	IPR004273
Domain	SET_dom	NSD2 PRDM9 KMT2A	4.56e-03	50	125	3	IPR001214
Domain	SET	NSD2 PRDM9 KMT2A	4.56e-03	50	125	3	PS50280
Domain	Post-SET_dom	NSD2 KMT2A	5.01e-03	16	125	2	IPR003616
Domain	PostSET	NSD2 KMT2A	5.01e-03	16	125	2	SM00508
Domain	HSP70	HYOU1 HSPA14	5.01e-03	16	125	2	PF00012
Domain	AcylCo_DH/oxidase_C	ACADL FANCG	5.01e-03	16	125	2	IPR009075
Domain	POST_SET	NSD2 KMT2A	5.01e-03	16	125	2	PS50868
Domain	HSP70_2	HYOU1 HSPA14	5.66e-03	17	125	2	PS00329
Domain	A/G_cyclase_CS	ADCY8 GUCY1A1	5.66e-03	17	125	2	IPR018297
Domain	HSP70_1	HYOU1 HSPA14	5.66e-03	17	125	2	PS00297
Domain	HSP70_3	HYOU1 HSPA14	5.66e-03	17	125	2	PS01036
Domain	-	ADCY8 GUCY1A1	6.34e-03	18	125	2	3.30.70.1230
Domain	Nucleotide_cyclase	ADCY8 GUCY1A1	6.34e-03	18	125	2	IPR029787
Domain	Hsp_70_fam	HYOU1 HSPA14	6.34e-03	18	125	2	IPR013126
Pathway	REACTOME_KINESINS	KIF26B KIF21A KIF4A KIF3A KIF4B	3.22e-05	57	91	5	MM15714
Pathway	REACTOME_KINESINS	KIF26B KIF21A KIF4A KIF3A KIF4B	4.49e-05	61	91	5	M977
Pathway	REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION	DOCK8 KIF26B KIF21A KIF4A KIF3A KIF4B	1.03e-04	116	91	6	MM15715
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NRIP1 ERCC1 PPFIBP1 KIF21A ZMYND8 PNISR ZKSCAN5 STAT3 KIF3A SEPTIN2 FRY SLF2 PDE4DIP EIF4G2 LRRCC1 WDFY3 HERC2 SEPTIN7 USPL1 QARS1 NIPBL GPRASP2	6.80e-09	1285	137	22	35914814
Pubmed	Functional proteomics mapping of a human signaling pathway.	ZFYVE16 DOCK8 RBBP6 ZMYND8 HIPK3 TRIM69 KANSL1 MCM3AP PDE4DIP EIF4G2 ASXL2 HERC2 ASCC3 QARS1 TP53BP2	1.38e-08	591	137	15	15231748
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF26B KIF21A KIF4A KIF3A KIF4B	3.47e-07	37	137	5	11416179
Pubmed	A draft of the human septin interactome.	SEPTIN2 SEPTIN1 SEPTIN7	5.95e-07	5	137	3	21082023
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NSD2 VPS13C KIF21A ZNF280C CHSY1 ADGRV1 ECPAS SEPTIN2 KANSL3 NRXN3 OSBPL5 KAT6B	1.35e-06	529	137	12	14621295
Pubmed	Kinesin family in murine central nervous system.	KIF4A KIF3A KIF4B	2.07e-06	7	137	3	1447303
Pubmed	Crosstalk between NSL histone acetyltransferase and MLL/SET complexes: NSL complex functions in promoting histone H3K4 di-methylation activity by MLL/SET complexes.	KANSL3 KANSL1 KMT2A	7.03e-06	10	137	3	24244196
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	RGPD2 EDC3 KIF4A PROSER1 KANSL3 TRIM69 KANSL1 ANLN ALDH18A1 KIF4B LSM14A ASXL2 HERC2 NIPBL IQGAP3 VPS13B	1.35e-05	1155	137	16	20360068
Pubmed	KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway.	KIF4A KIF4B	1.54e-05	2	137	2	36482480
Pubmed	A novel MLL-SEPT2 fusion variant in therapy-related myelodysplastic syndrome.	SEPTIN2 KMT2A	1.54e-05	2	137	2	18656699
Pubmed	Dedicator of cytokinesis 8 regulates signal transducer and activator of transcription 3 activation and promotes TH17 cell differentiation.	DOCK8 STAT3	1.54e-05	2	137	2	27350570
Pubmed	The multiple functions of kinesin-4 family motor protein KIF4 and its clinical potential.	KIF4A KIF4B	1.54e-05	2	137	2	30081192
Pubmed	Chromokinesin Kif4 promotes proper anaphase in mouse oocyte meiosis.	KIF4A KIF4B	1.54e-05	2	137	2	31067151
Pubmed	Cellular motor protein KIF-4 associates with retroviral Gag.	KIF4A KIF4B	1.54e-05	2	137	2	10559369
Pubmed	An epigenetic regulator emerges as microtubule minus-end binding and stabilizing factor in mitosis.	KANSL3 KANSL1	1.54e-05	2	137	2	26243146
Pubmed	Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis.	ANLN SEPTIN7	1.54e-05	2	137	2	10931866
Pubmed	STAT3 Activation Impairs the Stability of Th9 Cells.	STAT3 IL9	1.54e-05	2	137	2	28137893
Pubmed	KIF4 regulates midzone length during cytokinesis.	KIF4A KIF4B	1.54e-05	2	137	2	21565503
Pubmed	Identification of septins in neurofibrillary tangles in Alzheimer's disease.	SEPTIN2 SEPTIN1	1.54e-05	2	137	2	9811347
Pubmed	The requirement of SEPT2 and SEPT7 for migration and invasion in human breast cancer via MEK/ERK activation.	SEPTIN2 SEPTIN7	1.54e-05	2	137	2	27557506
Pubmed	Recurrent KAT6B/A::KANSL1 Fusions Characterize a Potentially Aggressive Uterine Sarcoma Morphologically Overlapping With Low-grade Endometrial Stromal Sarcoma.	KANSL1 KAT6B	1.54e-05	2	137	2	35575789
Pubmed	Key findings to expedite the diagnosis of hyper-IgE syndromes in infants and young children.	DOCK8 STAT3	1.54e-05	2	137	2	26592211
Pubmed	A novel microtubule-based motor protein (KIF4) for organelle transports, whose expression is regulated developmentally.	KIF4A KIF4B	1.54e-05	2	137	2	7929562
Pubmed	NSD2 promotes tumor angiogenesis through methylating and activating STAT3 protein.	NSD2 STAT3	1.54e-05	2	137	2	33742125
Pubmed	IL-9/STAT3/fatty acid oxidation-mediated lipid peroxidation contributes to Tc9 cell longevity and enhanced antitumor activity.	STAT3 IL9	1.54e-05	2	137	2	35192544
Pubmed	Whole genome expression microarray reveals novel roles for Kif4 in monocyte/macrophage cells.	KIF4A KIF4B	1.54e-05	2	137	2	31486502
Pubmed	Identification of novel loci for bipolar I disorder in a multi-stage genome-wide association study.	NRXN3 KAT6B	1.54e-05	2	137	2	24444492
Pubmed	Alternative Splicing of STAT3 Is Affected by RNA Editing.	ADAR STAT3	1.54e-05	2	137	2	28278381
Pubmed	Assignment of the kinesin family member 4 genes (KIF4A and KIF4B) to human chromosome bands Xq13.1 and 5q33.1 by in situ hybridization.	KIF4A KIF4B	1.54e-05	2	137	2	10773663
Pubmed	Missense Pathogenic variants in KIF4A Affect Dental Morphogenesis Resulting in X-linked Taurodontism, Microdontia and Dens-Invaginatus.	KIF4A KIF4B	1.54e-05	2	137	2	31616463
Pubmed	Kif4 regulates the expression of VEGFR1 through the PI3K/Akt signaling pathway in RAW264.7 monocytes/macrophages.	KIF4A KIF4B	1.54e-05	2	137	2	28350061
Pubmed	Successful long-term correction of autosomal recessive hyper-IgE syndrome due to DOCK8 deficiency by hematopoietic stem cell transplantation.	DOCK8 STAT3	1.54e-05	2	137	2	21058221
Pubmed	Kif4 interacts with EB1 and stabilizes microtubules downstream of Rho-mDia in migrating fibroblasts.	KIF4A KIF4B	1.54e-05	2	137	2	24658398
Pubmed	Protein-protein interaction analysis highlights the role of septins in membrane enclosed lumen and mRNA processing.	SEPTIN2 SEPTIN7	1.54e-05	2	137	2	31420262
Pubmed	Structural basis for the ATP-induced isomerization of kinesin.	KIF4A KIF4B	1.54e-05	2	137	2	23500491
Pubmed	Atopic dermatitis, STAT3- and DOCK8-hyper-IgE syndromes differ in IgE-based sensitization pattern.	DOCK8 STAT3	1.54e-05	2	137	2	24898675
Pubmed	Binding of murine leukemia virus Gag polyproteins to KIF4, a microtubule-based motor protein.	KIF4A KIF4B	1.54e-05	2	137	2	9658142
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	HYOU1 ACADL WDR81 ALDH1L1 COG3 ECPAS SEPTIN2 CLEC4F ALDH18A1 KMT2A QARS1 PGM2 IQGAP3	1.96e-05	807	137	13	30575818
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	EDC3 ITIH3 KIF3A SEPTIN2 FRY KANSL1 LSM14A HERC2 MAST3 PMCH	2.01e-05	475	137	10	31040226
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	EDC3 ZFYVE16 RBBP6 ZNF280C ZMYND8 KIF4A ADAR STAT3 SEPTIN2 EIF4G2 KMT2A LSM14A NIPBL TP53BP2	2.05e-05	934	137	14	33916271
Pubmed	A human MAP kinase interactome.	RBBP6 KIF26B NCKAP5L PNISR KIF3A HIPK3 KANSL1 MCM3AP SIMC1 HERC2	2.44e-05	486	137	10	20936779
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	EDC3 PCNX3 RBBP6 NSD2 PPFIBP1 NOA1 ZMYND8 KIF4A PNISR ANLN EIF4G2 ALDH18A1 KMT2A LSM14A HERC2 ASCC3 NIPBL IQGAP3	2.53e-05	1497	137	18	31527615
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EDC3 HYOU1 ZFYVE16 PPFIBP1 ECPAS STAT3 SEPTIN2 EIF4G2 ALDH18A1 ASCC3 SEPTIN7 QARS1	2.53e-05	708	137	12	39231216
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBBP6 NSD2 ZNF280C ZMYND8 KIF4A ADAR SLF2 ANLN SIMC1 EIF4G2 KMT2A SEPTIN7 NIPBL NPAT	2.59e-05	954	137	14	36373674
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RGPD2 KIF21A WDR81 KIF4A KIF3A SEPTIN2 FRY PDE4DIP KIF4B WDFY3 HERC2 SEPTIN7 NIPBL TP53BP2	2.87e-05	963	137	14	28671696
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN2 SEPTIN1 SEPTIN7	3.23e-05	16	137	3	22575789
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	EDC3 HYOU1 PPFIBP1 VPS13C ECPAS NCKAP5L STAT3 SIMC1 EIF4G2 LRRCC1 HERC2 SEPTIN7 TP53BP2	3.47e-05	853	137	13	28718761
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RGPD2 NRIP1 ZFYVE16 ZMYND8 ECPAS ASCC3 GPRASP2 TP53BP2 NPAT	4.44e-05	418	137	9	34709266
Pubmed	Structural analysis of septin 2, 6, and 7 complexes.	SEPTIN2 SEPTIN7	4.61e-05	3	137	2	16914550
Pubmed	[Replicative association analysis of genetic markers of cognitive traits with Alzheimer's disease in a Russian population].	NRIP1 CSMD1	4.61e-05	3	137	2	25845235
Pubmed	IL-9 promotes the pathogenesis of ulcerative colitis through STAT3/SOCS3 signaling.	STAT3 IL9	4.61e-05	3	137	2	30369485
Pubmed	Tumor formation via loss of a molecular motor protein.	KIF4A KIF4B	4.61e-05	3	137	2	16890532
Pubmed	A transgenic insertion causing cryptorchidism in mice.	FRY RXFP2	4.61e-05	3	137	2	11353515
Pubmed	KIF4 mediates anterograde translocation and positioning of ribosomal constituents to axons.	KIF4A KIF4B	4.61e-05	3	137	2	19158085
Pubmed	MiR-301a is activated by the Wnt/β-catenin pathway and promotes glioma cell invasion by suppressing SEPT7.	WNT1 SEPTIN7	4.61e-05	3	137	2	27006177
Pubmed	IL-9 is important for T-cell activation and differentiation in autoimmune inflammation of the central nervous system.	STAT3 IL9	4.61e-05	3	137	2	21674475
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX12P DDX11L8	4.61e-05	3	137	2	17611414
Pubmed	Identification of the human homologue of mouse KIF4, a kinesin superfamily motor protein.	KIF4A KIF4B	4.61e-05	3	137	2	10978527
Pubmed	IL6R-STAT3-ADAR1 (P150) interplay promotes oncogenicity in multiple myeloma with 1q21 amplification.	ADAR STAT3	4.61e-05	3	137	2	31413087
Pubmed	Structural insight into filament formation by mammalian septins.	SEPTIN2 SEPTIN7	4.61e-05	3	137	2	17637674
Pubmed	Mammalian ChlR1 has a role in heterochromatin organization.	DDX12P DDX11L8	4.61e-05	3	137	2	21854770
Pubmed	Characterization of human septin interactions.	SEPTIN2 SEPTIN7	4.61e-05	3	137	2	21767235
Pubmed	Clinical manifestations of hyper IgE syndromes.	DOCK8 STAT3	4.61e-05	3	137	2	21178271
Pubmed	STAT6-dependent regulation of Th9 development.	STAT3 IL9	4.61e-05	3	137	2	22180613
Pubmed	Self- and actin-templated assembly of Mammalian septins.	SEPTIN2 ANLN	4.61e-05	3	137	2	12479805
Pubmed	The Fanconi anemia protein, FANCG, binds to the ERCC1-XPF endonuclease via its tetratricopeptide repeats and the central domain of ERCC1.	ERCC1 FANCG	4.61e-05	3	137	2	20518486
Pubmed	An atomic model for the human septin hexamer by cryo-EM.	SEPTIN2 SEPTIN7	4.61e-05	3	137	2	34116125
Pubmed	Septin GTPases spatially guide microtubule organization and plus end dynamics in polarizing epithelia.	SEPTIN2 SEPTIN7	4.61e-05	3	137	2	21788367
Pubmed	ASCC3 promotes the immunosuppression and progression of non-small cell lung cancer by impairing the type I interferon response via CAND1-mediated ubiquitination inhibition of STAT3.	STAT3 ASCC3	4.61e-05	3	137	2	38148115
Pubmed	KIF4 motor regulates activity-dependent neuronal survival by suppressing PARP-1 enzymatic activity.	KIF4A KIF4B	4.61e-05	3	137	2	16630823
Pubmed	Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis.	SEPTIN2 SEPTIN7	4.61e-05	3	137	2	31865373
Pubmed	MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.	KANSL3 KANSL1	4.61e-05	3	137	2	27768893
Pubmed	CircKIF4A enhances osteosarcoma proliferation and metastasis by sponging MiR-515-5p and upregulating SLC7A11.	KIF4A KIF4B	4.61e-05	3	137	2	35579738
Pubmed	A physical interaction network of dengue virus and human proteins.	APOB EIF4G2 DDX11L8	4.67e-05	18	137	3	21911577
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	HYOU1 ZFYVE16 RBBP6 PPFIBP1 NOA1 KIF21A APOB ADAR STAT3 GLB1 ANLN ALDH18A1 SEPTIN7 QARS1 NIPBL PGM2	5.46e-05	1297	137	16	33545068
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	NRIP1 ZDHHC18 STAT3 HIPK3 KANSL1 GLB1 TTI1 WDFY3 KAT6B NIPBL	5.56e-05	536	137	10	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	NRIP1 ZDHHC18 STAT3 HIPK3 KANSL1 GLB1 TTI1 WDFY3 KAT6B NIPBL	5.73e-05	538	137	10	10512203
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZFYVE16 ECPAS HERC2 KAT6B DNAH9	5.93e-05	104	137	5	9205841
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NRIP1 CPAMD8 NSD2 VPS13C ADGRV1 COG3 ECPAS HIPK3 KANSL3 GUCY1A1 LPCAT3 OSBPL5 LSM14A CSMD1 KAT6B VPS13B ADGRD1	8.16e-05	1489	137	17	28611215
Pubmed	The mammalian septin MSF localizes with microtubules and is required for completion of cytokinesis.	SEPTIN2 SEPTIN7	9.19e-05	4	137	2	12388755
Pubmed	The long non-coding RNA LINC00473 contributes to cell proliferation via JAK-STAT3 signaling pathway by regulating miR-195-5p/SEPT2 axis in prostate cancer.	STAT3 SEPTIN2	9.19e-05	4	137	2	32440687
Pubmed	Kinesin KIF4 regulates intracellular trafficking and stability of the human immunodeficiency virus type 1 Gag polyprotein.	KIF4A KIF4B	9.19e-05	4	137	2	18684836
Pubmed	Molecular Recognition at Septin Interfaces: The Switches Hold the Key.	SEPTIN2 SEPTIN7	9.19e-05	4	137	2	32910969
Pubmed	Kif4 Is Essential for Mouse Oocyte Meiosis.	KIF4A KIF4B	9.19e-05	4	137	2	28125646
Pubmed	Males absent on the first (MOF): from flies to humans.	KANSL3 KANSL1	9.19e-05	4	137	2	17694080
Pubmed	Sept12 is a component of the mammalian sperm tail annulus.	SEPTIN2 SEPTIN7	9.19e-05	4	137	2	17685441
Pubmed	Analysis of the human VPS13 gene family.	VPS13C VPS13B	9.19e-05	4	137	2	15498460
Pubmed	Tubular STAT3 Limits Renal Inflammation in Autosomal Dominant Polycystic Kidney Disease.	STAT3 KIF3A	9.19e-05	4	137	2	32238474
Pubmed	Expression profiling the human septin gene family.	SEPTIN2 SEPTIN1	9.19e-05	4	137	2	15915442
Pubmed	Septins 2, 7 and 9 and MAP4 colocalize along the axoneme in the primary cilium and control ciliary length.	SEPTIN2 SEPTIN7	9.19e-05	4	137	2	23572511
Pubmed	A single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9.	STAT3 IL9	9.19e-05	4	137	2	8756628
Pubmed	Biochemical and cell biological analyses of a mammalian septin complex, Sept7/9b/11.	SEPTIN2 SEPTIN7	9.19e-05	4	137	2	15485874
Pubmed	Interaction of the S100A4 (Mts1) protein with septins Sept2, Sept6, and Sept7 in vitro.	SEPTIN2 SEPTIN7	9.19e-05	4	137	2	14531065
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ZFYVE16 ZNF280C ZMYND8 ECPAS ADAR KANSL3 ANLN ALDH18A1 TP53BP2	1.12e-04	472	137	9	38943005
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	HYOU1 DOCK8 ZMYND8 KIF4A ECPAS ADAR SEPTIN2 KANSL3 ANLN EIF4G2 KMT2A LSM14A ASXL2 NIPBL	1.22e-04	1103	137	14	34189442
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	RBBP6 ZNF280C ZMYND8 KIF4A ADAR SEPTIN2 SEPTIN7	1.37e-04	283	137	7	30585729
Pubmed	Replication of signals from recent studies of Crohn's disease identifies previously unknown disease loci for ulcerative colitis.	STAT3 HERC2	1.53e-04	5	137	2	18438405
Pubmed	Septins regulate bacterial entry into host cells.	SEPTIN2 SEPTIN7	1.53e-04	5	137	2	19145258
Pubmed	Novel Sm-like proteins with long C-terminal tails and associated methyltransferases.	EDC3 LSM14A	1.53e-04	5	137	2	15225602
Pubmed	Artesunate inhibits adipogeneis in 3T3-L1 preadipocytes by reducing the expression and/or phosphorylation levels of C/EBP-α, PPAR-γ, FAS, perilipin A, and STAT-3.	STAT3 PLIN2	1.53e-04	5	137	2	27109481
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF26B KIF21A KIF4A KIF3A KIF4B	2.70e-06	46	87	5	622
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 LYST WDFY3	8.85e-06	9	87	3	1230
GeneFamily	Septins	SEPTIN2 SEPTIN1 SEPTIN7	2.97e-05	13	87	3	732
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	NSD2 PRDM9 KMT2A	5.78e-04	34	87	3	487
GeneFamily	PHD finger proteins	NSD2 ZMYND8 KMT2A KAT6B	9.33e-04	90	87	4	88
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ZFYVE16 WDR81 AATK CSMD1 TP53BP2	1.81e-03	181	87	5	694
GeneFamily	Dyneins, axonemal	DNAH8 DNAH9	2.97e-03	17	87	2	536
GeneFamily	Heat shock 70kDa proteins	HYOU1 HSPA14	2.97e-03	17	87	2	583
GeneFamily	Aldehyde dehydrogenases	ALDH1L1 ALDH18A1	3.71e-03	19	87	2	398
GeneFamily	PWWP domain containing	NSD2 ZMYND8	4.97e-03	22	87	2	1147
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	ZDHHC18 DOCK8 RBBP6 VPS13C CHSY1 PNISR ADAR LYST STAT3 SEPTIN2 KANSL1 GVINP1 SLF2 PDE4DIP EIF4G2 SEPTIN1 KMT2A LSM14A ASXL2 ASCC3 SEPTIN7 KAT6B NIPBL VPS13B MAST3 NPAT	4.62e-08	1492	136	26	M40023
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN	CLCA4 EDC3 PLVAP CHSY1 PPBP ADCY8 PDE4DIP EIF4G2 IQGAP3 MAST3	2.08e-05	363	136	10	M6315
Coexpression	IWANAGA_CARCINOGENESIS_BY_KRAS_PTEN_DN	CLCA4 EDC3 PLVAP CHSY1 PPBP ADCY8 PDE4DIP EIF4G2 IQGAP3 MAST3	2.56e-05	372	136	10	MM1043
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 KIF26B APOB ADGRV1 XIRP2 CSMD1 DNAH9	1.68e-06	184	137	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK8 VPS13C LYST SLF2 KMT2A ASCC3 NIPBL	1.68e-06	184	137	7	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 KIF26B APOB ADGRV1 XIRP2 CSMD1 DNAH9	1.68e-06	184	137	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 KIF26B APOB ADGRV1 XIRP2 CSMD1 DNAH9	1.68e-06	184	137	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ACADL KIF21A RFX6 ADGRV1 BMP3 FRY NRXN3	2.38e-06	194	137	7	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	DOCK8 VPS13C PNISR ADAR KANSL1 KMT2A NIPBL	2.91e-06	200	137	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	RBBP6 VPS13C PPBP ADAR STAT3 KMT2A NIPBL	2.91e-06	200	137	7	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHSY1 LYST SIMC1 OSBPL5 SEPTIN1 DNAH8	1.19e-05	164	137	6	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHSY1 LYST SIMC1 OSBPL5 SEPTIN1 DNAH8	1.19e-05	164	137	6	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHSY1 LYST SIMC1 OSBPL5 SEPTIN1 DNAH8	1.19e-05	164	137	6	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C RFX6 CDCP1 ADAR PDE4DIP TTI1	1.66e-05	174	137	6	f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	KIF26B NSD2 ZMYND8 NRXN3 KANSL1 SLF2	2.42e-05	186	137	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	KIF26B NSD2 ZMYND8 NRXN3 KANSL1 SLF2	2.42e-05	186	137	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	PROSER1 KANSL3 KANSL1 SLC22A16 ANLN IQGAP3	2.72e-05	190	137	6	3f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ACADL KIF4A ADGRV1 BMP3 ANLN IQGAP3	2.80e-05	191	137	6	39220f4a345e328f7fa4fd462a0abeea821b3e02
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ACADL KIF4A RFX6 ADGRV1 NRXN3 IQGAP3	2.89e-05	192	137	6	25378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell	PBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PROSER1 KANSL3 KANSL1 SLC22A16 ANLN IQGAP3	2.89e-05	192	137	6	c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	ZFYVE16 KIF21A ADGRV1 ASXL2 WDFY3 VPS13B	2.97e-05	193	137	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	PCW_13-14-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ACADL KIF4A ADGRV1 BMP3 ANLN IQGAP3	3.06e-05	194	137	6	c197e4acbff42a9f0410b6801c2bfcf6160aefc1
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZDHHC18 ABCA13 ADGRV1 WDFY3 CSMD1 DNAH9	3.15e-05	195	137	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ACADL KIF21A ADGRV1 ADCY8 BMP3 FRY	3.15e-05	195	137	6	ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZDHHC18 ABCA13 ADGRV1 WDFY3 CSMD1 DNAH9	3.15e-05	195	137	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF21A ADGRV1 KIF3A PLIN2 BMP3 NRXN3	3.33e-05	197	137	6	1a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KIF21A ADGRV1 CDCP1 BMP3 NRXN3 TP53BP2	3.43e-05	198	137	6	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	PCW_13-14-Epithelial\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ACADL KIF21A ADGRV1 ADCY8 BMP3 FRY	3.43e-05	198	137	6	48eb6f69a464a34ab32e8d425a22b9d45ec20428
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	PPFIBP1 BMP3 NRXN3 GUCY1A1 PDE4DIP EIF4G2	3.63e-05	200	137	6	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	COVID-19-kidney-Mito-rich_Int\|kidney / Disease (COVID-19 only), tissue and cell type	LAMA2 PRDM9 NRXN3 CSMD1 DNAH9	4.95e-05	129	137	5	57b705106aec7bbfc587de1ccd4f2335fc44dd6f
Disease	Bipolar I disorder	NRXN3 SLC22A16 KAT6B	1.41e-05	11	132	3	C0853193
Disease	Hyper-Immunoglobulin E Syndrome, Autosomal Recessive	DOCK8 STAT3	5.94e-05	3	132	2	C1968689
Disease	electrodermal activity measurement	RBBP6 NRXN3	5.94e-05	3	132	2	EFO_0006866
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	5.94e-05	3	132	2	DOID:0111590 (implicated_via_orthology)
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX12P DDX11L8	5.94e-05	3	132	2	DOID:0060535 (implicated_via_orthology)
Disease	Hyper-Immunoglobulin E Syndrome, Autosomal Dominant	DOCK8 STAT3	5.94e-05	3	132	2	C2936739
Disease	Malignant neoplasm of breast	NRIP1 NSD2 NOA1 LAMA2 COG3 PKDREJ ADAR STAT3 HERC2 KAT6B DNAH9 NIPBL HSPA14 VPS13B TP53BP2	9.58e-05	1074	132	15	C0006142
Disease	Job Syndrome	DOCK8 STAT3	1.18e-04	4	132	2	C3887645
Disease	Chediak-Higashi syndrome (implicated_via_orthology)	LYST WDFY3	1.18e-04	4	132	2	DOID:2935 (implicated_via_orthology)
Disease	eosinophil percentage of leukocytes	NRIP1 ZMYND8 ENTHD1 RFX6 KIF3A SEPTIN2 KANSL3 KANSL1 GLB1 LPCAT3 MAST3 IL9	1.37e-04	746	132	12	EFO_0007991
Disease	Bone Diseases, Developmental	KIF3A GLB1 NIPBL	2.37e-04	27	132	3	C0005941
Disease	pack-years measurement, systolic blood pressure	FRY NRXN3 ZSWIM7	4.73e-04	34	132	3	EFO_0006335, EFO_0006526
Disease	chylomicron measurement, triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	APOB RXFP2 MAST3	4.73e-04	34	132	3	EFO_0008317, EFO_0008596, EFO_0020947
Disease	retinal detachment, retinal break	CPAMD8 LAMA2 BMP3	5.16e-04	35	132	3	EFO_0005773, EFO_0010698
Disease	Cornelia De Lange Syndrome	KMT2A NIPBL	5.46e-04	8	132	2	C0270972
Disease	neutrophil percentage of granulocytes	ZDHHC18 RFX6 SEPTIN2 KANSL3 KANSL1 GLB1	5.81e-04	228	132	6	EFO_0007994
Disease	autism spectrum disorder	ZNF354A DOCK8 ADCY8 ITIH3 KANSL1	6.98e-04	156	132	5	EFO_0003756
Disease	response to angiotensin-converting enzyme inhibitor, Cough	ASXL2 CSMD1 VPS13B	1.15e-03	46	132	3	EFO_0005325, HP_0012735
Disease	Mouth Diseases	FANCG HSPA14	1.27e-03	12	132	2	C0026636
Disease	systolic blood pressure, cigarettes per day measurement	FRY NRXN3	1.50e-03	13	132	2	EFO_0006335, EFO_0006525
Disease	Drug habituation	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0013170
Disease	Drug abuse	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0013146
Disease	Prescription Drug Abuse	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C4316881
Disease	Substance-Related Disorders	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0236969
Disease	Drug Use Disorders	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0013222
Disease	Drug Dependence	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C1510472
Disease	Substance Dependence	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0038580
Disease	Substance Use Disorders	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CDCP1 NRXN3 CSMD1 DNAH8	1.80e-03	115	132	4	C0029231
Disease	Substance abuse problem	CDCP1 NRXN3 CSMD1 DNAH8	1.86e-03	116	132	4	C0740858
Disease	leukemia	STAT3 FANCG KMT2A	1.94e-03	55	132	3	C0023418
Disease	Germ Cell Cancer	ERCC1 DPPA3	2.01e-03	15	132	2	C0740345
Disease	Embryonal Neoplasm	ERCC1 DPPA3	2.01e-03	15	132	2	C0027654
Disease	Neoplasms, Germ Cell and Embryonal	ERCC1 DPPA3	2.01e-03	15	132	2	C0027658
Disease	Germ cell tumor	ERCC1 DPPA3	2.01e-03	15	132	2	C0205851
Disease	Neoplasms, Embryonal and Mixed	ERCC1 DPPA3	2.01e-03	15	132	2	C0205852
Disease	Cancer, Embryonal	ERCC1 DPPA3	2.01e-03	15	132	2	C0751364
Disease	Cancer, Embryonal and Mixed	ERCC1 DPPA3	2.01e-03	15	132	2	C0751365
Disease	amenorrhea, response to antineoplastic agent	APOB ADCY8	2.01e-03	15	132	2	EFO_0010269, GO_0097327
Disease	Liver carcinoma	PLVAP KIF4A ITIH3 ANLN KMT2A MTBP CSMD1 IQGAP3	2.07e-03	507	132	8	C2239176
Disease	colorectal health	ADGRV1 ADCY8 NRXN3 HERC2 CSMD1	2.15e-03	201	132	5	EFO_0008460
Disease	Chromosome Aberrations	ERCC1 KMT2A	2.29e-03	16	132	2	C0008625
Disease	response to triptolide, cytotoxicity measurement	CSMD1 TP53BP2	2.29e-03	16	132	2	EFO_0006952, EFO_0007662
Disease	Autosome Abnormalities	ERCC1 KMT2A	2.29e-03	16	132	2	C0004403
Disease	puberty onset measurement	ECPAS KANSL1 SLF2 HERC2	2.44e-03	125	132	4	EFO_0005677
Disease	Muscle hypotonia	NSD2 KANSL1	2.58e-03	17	132	2	C0026827
Disease	phosphatidylcholine 40:6 measurement	CSMD1 DNAH9	2.58e-03	17	132	2	EFO_0010389
Disease	Astigmatism	ABCA13 CHSY1 BMP3 HERC2	2.74e-03	129	132	4	HP_0000483
Disease	obsolete_red blood cell distribution width	PMS2P1 NRIP1 DOCK8 RC3H1 APOB PLIN2 KANSL1 SLC22A16 ANLN LPCAT3 SIMC1 LSM14A ASXL2 MAST3	2.89e-03	1347	132	14	EFO_0005192
Disease	response to methotrexate, juvenile idiopathic arthritis	ENTHD1 CSMD1	3.23e-03	19	132	2	EFO_0002609, GO_0031427
Disease	renovascular hypertension (biomarker_via_orthology)	LAMA2 EIF4G2	3.23e-03	19	132	2	DOID:1591 (biomarker_via_orthology)
Disease	glycine measurement	ALDH1L1 ADGRV1 GVINP1 MAST3	3.40e-03	137	132	4	EFO_0009767
Disease	Profound Mental Retardation	DOCK8 FRY KANSL1 ASCC3	3.58e-03	139	132	4	C0020796
Disease	Mental Retardation, Psychosocial	DOCK8 FRY KANSL1 ASCC3	3.58e-03	139	132	4	C0025363
Disease	Mental deficiency	DOCK8 FRY KANSL1 ASCC3	3.58e-03	139	132	4	C0917816
Disease	citrulline measurement	KIF26B ALDH18A1	3.58e-03	20	132	2	EFO_0009777
Disease	Intellectual Disability	DOCK8 NSD2 KIF4A FRY KANSL1 ASCC3 ZMYM6	4.07e-03	447	132	7	C3714756
Disease	progression free survival, ovarian serous carcinoma	ABCA13 IQGAP3	4.33e-03	22	132	2	EFO_0004920, EFO_1001516

Protein segments in the cluster

Peptide	Gene	Start	Entry
TSLELGKSLFTNTAL	ZNF354C	161	Q86Y25
GKSLFTNTALVTQQS	ZNF354C	166	Q86Y25
KGFTNLSTTLSAQEL	ADCY8	421	P40145
FNLTSLTKSENILSA	BMP3	116	P12645
NLSTNIFSNLTSLGK	CPN2	111	P22792
IFSNLTSLGKLTLNF	CPN2	116	P22792
ATSNQILLRFSAKSG	CSMD1	1706	Q96PZ7
ILNGSKVFISNGSLS	ACADL	196	P28330
SLSEQTALNLTKTFL	ADGRD1	311	Q6QNK2
TSGKQLDLLFSVTLT	CDCP1	646	Q9H5V8
SSNTGDTQRLKIASL	CCDC171	6	Q6TFL3
QSSGKSTVLNALFGL	GVINP1	1491	Q7Z2Y8
SLSVKGQSSQLLTND	ADGRV1	5821	Q8WXG9
NSSETSVLNKLLGSV	ABCA13	536	Q86UQ4
SFGTLRKNQSSEDIL	TP53BP2	471	Q13625
SFSSSVKVENTLLGL	ASXL2	231	Q76L83
GLFSAASLKLSALTQ	ARIH2OS	131	Q8N7S6
NISLLSNKTSSLNLS	RC3H1	1096	Q5TC82
LNILDDSGRKQTSSF	RFX6	841	Q8HWS3
LSSLTTNSQLKALFD	KAT6B	531	Q8WYB5
QLSALKTLSLSGNQL	LRRC57	106	Q8N9N7
NNRITSLSGLQKSFT	LRRC9	986	Q6ZRR7
NENLILSGKSSQLLS	NPAT	521	Q14207
LSGKSSQLLSQDTSL	NPAT	526	Q14207
GELSSTLDLANTLQK	MBD3L1	81	Q8WWY6
LFSKRQLGSSNSLTA	ENTHD1	156	Q8IYW4
IGFQRSILLSKSENS	DAOA	26	P59103
DTSLLEFLKISNSGL	OR4D2	191	P58180
TLVSKLNLTNDGNLS	MAGEB1	176	P43366
SALFQQKLQLTTGSL	NCKAP5L	101	Q9HCH0
LLTSSLQKSSSLGNL	PPFIBP1	456	Q86W92
KDFQTQSLTGNSILA	HERC2	1236	O95714
TLSLSSVGNTKFVLD	ANLN	946	Q9NQW6
SAKLEQLASRSNSLG	KIF26B	1656	Q2KJY2
IQTLSLFNSLSSKGD	MCM3AP	1406	O60318
DFKGLVSNLTLSSNI	GLB1	491	P16278
GLFGTNTNSKLRTLS	ECPAS	361	Q5VYK3
NKTDSQTLLTTFGSL	ERCC1	246	P07992
LKGSLSQELSKSFLT	PCNX3	241	Q9H6A9
GLTASQSNLTKELNF	PLVAP	76	Q9BX97
KETSSNTAFLLISGL	IGLV11-55	91	A0A075B6I3
SSFGKILSSQQALQL	DNAH8	446	Q96JB1
VFLSKAQLSSSLQEG	NSD2	46	O96028
TLSVSGSNLLQSFKE	NIPBL	2456	Q6KC79
LSFQFKTNVSTGLLL	NRXN3	51	Q9Y4C0
ASFLATKNLSLSQQL	PGM2	451	Q96G03
GLSNFLKSNSISEEL	KANSL1	366	Q7Z3B3
SGFQELSLNKLATSL	LPCAT3	21	Q6P1A2
LSLNKLATSLGASEQ	LPCAT3	26	Q6P1A2
GKQDSTLLASLLQSF	NRIP1	126	P48552
FTQDTRSLKTQLSQG	LSM14A	166	Q8ND56
NLSFSTKNESGIILL	LAMA2	2551	P24043
TLLTELFSNKGSGTL	NAGS	356	Q8N159
ESITNELSLFSKTQG	EDC3	376	Q96F86
ELSLFSKTQGQQVSS	EDC3	381	Q96F86
LLLETLNGSQSGASK	FANCG	161	O15287
ATTSLLTLLLAFGKN	PMS2P1	111	A4D2B8
TKINLSLSTLGNVIS	KIF3A	271	Q9Y496
NFTKIGTLRSQALTT	HIPK3	581	Q9H422
SSLISLLKQEGIATS	EIF4G2	601	P78344
TTAGNALTFLKSLLE	IL9	116	P15248
KLQATLQGLSTKTTF	IQGAP3	1486	Q86VI3
KSLQSLDLSFNGILQ	LRRC66	171	Q68CR7
LSLSTSKLNSLAIGL	ALDH18A1	426	P54886
SASISLAQLTKTANL	RBBP6	106	Q7Z6E9
ALKGFLTSNDTNLIN	PROSER1	471	Q86XN7
KELSRTANLLNASGS	PRDM9	131	Q9NQV7
FLSKINGGLTSISDL	ANP32C	46	O43423
SLNIAGLSLDFSSKL	APOB	1756	P04114
ESTLTKLGNTISSLF	HYOU1	571	Q9Y4L1
NNFNLKTSGIVLSSL	DOCK8	1266	Q8NF50
SDSSALNLAKNIGLT	ADAR	311	P55265
SLLGASESISKNKTQ	COG3	591	Q96JB2
LSFSDLGLNNITAKA	CPAMD8	876	Q8IZJ3
LSRQGSLSESTLKFL	DDX11L8	586	A8MPP1
QGSLSQSTLKFLLLN	DDX12P	606	Q92771
TSSLLTQSQKLTGSL	LYST	2111	Q99698
SGNKISLRTTALENT	MAST3	1026	O60307
SKLTRLLQDSLGGNS	KIF4A	291	O95239
SKLTRLLQDSLGGNS	KIF4B	291	Q2VIQ3
LQGLSFSLQDISSKT	KANSL3	751	Q9P2N6
GSISNLLIKASQQSL	KMT2A	3376	Q03164
TLNKTNLTELKSFGS	DNAH9	3166	Q9NYC9
QQLLLKGFTSLTTTD	FRY	2101	Q5TBA9
KGFTSLTTTDLTLQL	FRY	2106	Q5TBA9
TDKTSTTGSILNLNL	ZMYND8	506	Q9ULU4
TTGSILNLNLDRSKA	ZMYND8	511	Q9ULU4
ESVSSGFKLQNNSLL	CFAP74	1361	Q9C0B2
LSLLLTALASSTKGQ	PPBP	26	P02775
TLIKNLSNLTINASS	DPPA3	36	Q6W0C5
SLFSQGILLSASKSI	PMCH	16	P20382
ATNAGKSTLFNTLLE	NOA1	346	Q8NC60
NSLKSELGLQSITFS	FPGT	386	O14772
LGLTNSTKQNSVLLL	MTBP	326	Q96DY7
SNILVFKLGGTSLSL	HSPA14	191	Q0VDF9
LSALLDGKATLTFLN	OSBPL5	511	Q9H0X9
QTSASQFILLGLSEK	OR1M1	6	Q8NGA1
SLSLFTSLGLSEQKA	QARS1	6	P47897
ETRLSTSLSGLNEKN	AATK	976	Q6ZMQ8
LSSTTKSADQLNGLL	RGPD2	1651	P0DJD1
SKLLLTTNNSGLEKT	SLC22A16	551	Q86VW1
ASFITNDLLGSALTK	ITIH3	201	Q06033
RGSINTFLLTTKSDL	PKDREJ	1276	Q9NTG1
SGFLSLLTTANARTK	GPRASP2	721	Q96D09
TFTGNLSFLASLQLS	SIMC1	146	Q8NDZ2
FSSLKNLGELDLSSN	RXFP2	301	Q8WXD0
KFSLESLGISSLQTS	TGM4	621	P49221
KTDQIFLTTQGFLTS	SLF2	781	Q8IX21
KLTFFNSTLNTSGLV	ALDH1L1	241	O75891
LTGALRSFSNVTKQD	ASCC3	6	Q8N3C0
SGSLSFLSNSLKKLV	CHSY1	501	Q86X52
QTLNFLKSSLENTSI	CLEC4F	196	Q8N1N0
LTSGNTDLSQKSLQL	CLCA4	476	Q14CN2
LSANQKTRLFALGSS	PRDM10-DT	31	Q96N53
LGKSTLINSLFLTNL	SEPTIN1	41	Q8WYJ6
SFSLTLTNNLDKVGI	TRIM69	431	Q86WT6
IIKGDLTSTLNSLSQ	XIRP2	1661	A4UGR9
NTGILKTNTLLSQES	USPL1	616	Q5W0Q7
LLTTINLLASSGQKT	WDFY3	126	Q8IZQ1
LLSLKFLFGSSATQA	ZSWIM7	31	Q19AV6
SKLTRLLQDSLGGNS	KIF21A	326	Q7Z4S6
LGKSTLINSLFLTDL	SEPTIN7	61	Q16181
QFSSTTKRGLSIEQL	STAT3	511	P40763
NLSSKDLLTNSQGIS	SPATA31D1	1231	Q6ZQQ2
GLDSSLSLQSRKQSL	VPS13C	1111	Q709C8
VSLSSSRQTLKGDLQ	UBQLNL	401	Q8IYU4
ENFTLLASLGLASSK	ZNF773	46	Q6PK81
TELSSDLGLQALFKS	ZMYM6	1236	O95789
ASSTNLLTDSKSLQL	WNT1	41	P04628
LLASLSNLNGSLSVK	VPS13B	2156	Q7Z7G8
GSSFLLSINDFLLKT	VPS13B	2181	Q7Z7G8
KGTLTSITNLATSLA	VPS13B	3706	Q7Z7G8
VSDSLLTSSKGQLQK	PLIN2	366	Q99541
KQLAQSSALASLTGL	PNISR	371	Q8TF01
SGLGKSTLINSLFLT	SEPTIN2	46	Q15019
KNSQVGSDNSSILLF	ZNF280C	131	Q8ND82
STQTQDSSFQGLILK	ZNF354A	96	O60765
KLSSENFRGTLTSLA	WDR81	1906	Q562E7
LRAQGSNFLSTLKET	ZDHHC18	261	Q9NUE0
LKDSQELTASLLSTG	ZKSCAN5	196	Q9Y2L8
ELTASLLSTGSQKLV	ZKSCAN5	201	Q9Y2L8
NESSLNEKTLKGLTS	ZFYVE16	76	Q7Z3T8
SQDDQGKFSTLSLLL	TTI1	391	O43156
GGTLKDFLNSFSTLL	GUCY1A1	156	Q02108
KGLQSISELSLDSTL	LRRCC1	31	Q9C099
FSVLSSSKSLVNLNL	NLRP13	1001	Q86W25
GTQFKNSLSSLLETL	MYO1H	571	Q8N1T3
QGSQLTERLTSKLST	PDE4DIP	1536	Q5VU43