Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionN,N-dimethylaniline monooxygenase activity

FMO2 FMO3 FMO6P

1.85e-076433GO:0004499
GeneOntologyMolecularFunctionhypotaurine monooxygenase activity

FMO2 FMO3

4.51e-055432GO:0047822
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

FMO2 FMO3 FMO6P

8.69e-0540433GO:0016709
DomainFMO-like

FMO2 FMO3

4.92e-055422PF00743
DomainFlavin_mOase

FMO2 FMO3

4.92e-055422IPR000960
DomainFlavin_mOase-like

FMO2 FMO3

4.92e-055422IPR020946
DomainDiMe-aniline_mOase

FMO2 FMO3

4.92e-055422IPR012143
DomainPROTEIN_KINASE_TYR

FGFR1 PEAK1 EPHA3

1.35e-0397423PS00109
DomainTyr_kinase_AS

FGFR1 PEAK1 EPHA3

1.35e-0397423IPR008266
Domain-

FMO2 FMO3

7.04e-03564223.50.50.60
DomainFAD/NAD-binding_dom

FMO2 FMO3

7.29e-0357422IPR023753
PathwayWP_CATALYTIC_CYCLE_OF_MAMMALIAN_FLAVINCONTAINING_MONOOXYGENASES_FMOS

FMO2 FMO3

5.29e-055332M39449
Pubmed

Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.

FMO2 FMO3 FMO6P

3.51e-08643312527699
Pubmed

Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.

FMO2 FMO3

1.49e-0624321542660
Pubmed

Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American.

FMO3 FMO6P

4.48e-06343228413702
Pubmed

Co-administration of RANKL and CTLA4 Antibodies Enhances Lymphocyte-Mediated Antitumor Immunity in Mice.

CTLA4 TNFRSF11A

4.48e-06343228634284
Pubmed

Nicotine-N'-Oxidation by Flavin Monooxygenase Enzymes.

FMO2 FMO3

4.48e-06343230381441
Pubmed

TAX1BP1 Restrains Virus-Induced Apoptosis by Facilitating Itch-Mediated Degradation of the Mitochondrial Adaptor MAVS.

MAVS TAX1BP1

4.48e-06343227736772
Pubmed

Quantitative analysis of FMO gene mRNA levels in human tissues.

FMO2 FMO3

8.94e-06443216183778
Pubmed

The mammalian flavin-containing monooxygenases: molecular characterization and regulation of expression.

FMO2 FMO3

1.49e-0554328128486
Pubmed

Flavin-Containing Monooxygenase 1 Catalyzes the Production of Taurine from Hypotaurine.

FMO2 FMO3

1.49e-05543232156684
Pubmed

A nomenclature for the mammalian flavin-containing monooxygenase gene family based on amino acid sequence identities.

FMO2 FMO3

1.49e-0554328311461
Pubmed

Isolation of LERK-5: a ligand of the eph-related receptor tyrosine kinases.

FGFR1 EPHA3

2.23e-0564328559144
Pubmed

Human-mouse comparative mapping of the genomic region containing CDK6: localization of an evolutionary breakpoint.

SAMD9L FGL2

5.35e-05943210384057
Pubmed

Genome-wide association identifies genetic variants associated with lentiform nucleus volume in Nā€‰=ā€‰1345 young and elderly subjects.

FMO3 FMO6P

5.35e-05943222903471
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

FMO2 FMO3 FMO6P

7.63e-056643319898482
Pubmed

TAX1BP1 protects against myocardial infarction-associated cardiac anomalies through inhibition of inflammasomes in a RNF34/MAVS/NLRP3-dependent manner.

MAVS TAX1BP1

8.15e-051143236654301
Pubmed

Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS.

FASTKD5 MAVS MYO19

8.34e-056843336966392
Pubmed

An Eph-related receptor protein tyrosine kinase gene segmentally expressed in the developing mouse hindbrain.

FGFR1 EPHA3

9.78e-05124321281307
Pubmed

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.

UBA5 FMO2 TRAPPC8

9.89e-057243333726789
Pubmed

Genomic characterisation of a Fgf-regulated gradient-based neocortical protomap.

FGFR1 EPHA3

1.15e-041343216079153
Pubmed

ES cell neural differentiation reveals a substantial number of novel ESTs.

PEG3 EPHA3

1.35e-041443211793228
Pubmed

Mouse Twist is required for fibroblast growth factor-mediated epithelial-mesenchymal signalling and cell survival during limb morphogenesis.

FGFR1 TBX4

1.35e-041443212175489
Pubmed

Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart.

TBX4 EPHA3

1.55e-041543216380715
Pubmed

Spatial and temporal expression of molecular markers and cell signals during normal development of the mouse patellar tendon.

FGFR1 FMOD

1.77e-041643221939397
Pubmed

Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities.

TBX4 EPHA3

2.01e-041743219168674
Pubmed

Fgf21 regulates T-cell development in the neonatal and juvenile thymus.

FGFR1 TNFRSF11A

2.26e-041843228336912
Pubmed

Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.

PALS2 KCNJ4

2.52e-041943215024025
Pubmed

Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy.

MAVS MYO19 TAX1BP1

2.54e-049943331723608
Pubmed

Genome-wide association analysis of red blood cell traits in African Americans: the COGENT Network.

LMF1 F8

2.80e-042043223446634
Pubmed

FGF9 suppresses meiosis and promotes male germ cell fate in mice.

FGFR1 TDRD1

3.40e-042243220833365
Pubmed

HuR controls lung branching morphogenesis and mesenchymal FGF networks.

FGFR1 TBX4

3.72e-042343221515253
Pubmed

Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver.

FMO2 FMO3

4.05e-042443234215813
Pubmed

Gene expression profiles of mouse submandibular gland development: FGFR1 regulates branching morphogenesis in vitro through BMP- and FGF-dependent mechanisms.

FZD6 FGFR1

4.05e-042443212421715
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD6 FGFR1

4.05e-04244329096311
Pubmed

Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung.

FGFR1 TBX4

4.05e-042443219097117
Pubmed

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

FZD6 CTLA4

4.05e-04244328626800
Pubmed

Global gene expression analysis of murine limb development.

KMT2C TBX4 PEG3

4.15e-0411743322174793
Pubmed

Identification of tyrosine kinases expressed in the male mouse gubernaculum during development.

FGFR1 EPHA3

4.40e-042543215254900
Pubmed

A set of anonymous DNA clones as markers for mouse gene mapping.

FGFR1 CTLA4

4.40e-04254321351769
Pubmed

Human chromosome 7: DNA sequence and biology.

SPAM1 SAMD9L PALS2 TAX1BP1 FGL2

5.07e-0453643512690205
Pubmed

Genetic variation in metabolizing enzyme and transporter genes: comprehensive assessment in 3 major East Asian subpopulations with comparison to Caucasians and Africans.

FMO2 FMO3

5.14e-042743220173083
Pubmed

Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.

FGFR1 EPHA3

5.53e-042843224427155
Pubmed

Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.

FMO2 FMO3

6.35e-043043220529763
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

FGFR1 SPAM1 FOXN3 TBX4

7.42e-0433143420634891
Pubmed

DR3 signaling modulates the function of Foxp3+ regulatory T cells and the severity of acute graft-versus-host disease.

CTLA4 FGL2

7.69e-043343227760760
Pubmed

GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.

FGFR1 EPHA3

9.67e-043743222465667
Pubmed

Targeting promiscuous heterodimerization overcomes innate resistance to ERBB2 dimerization inhibitors in breast cancer.

FGFR1 EPHA3

1.13e-034043230898150
Pubmed

The apical ectodermal ridge of the mouse model of ectrodactyly Dlx5;Dlx6-/- shows altered stratification and cell polarity, which are restored by exogenous Wnt5a ligand.

FZD6 FGFR1

1.19e-034143226685160
Cytoband1q24.3

FMO2 FMO3 FMO6P

8.63e-07204331q24.3
Cytoband7p15

PALS2 TAX1BP1

7.74e-05144327p15
CytobandEnsembl 112 genes in cytogenetic band chr1q24

FMO2 FMO3 FMO6P

2.46e-04129433chr1q24
Cytoband3q22.1

UBA5 COL6A6

7.20e-04424323q22.1
Cytoband17q12

MYO19 HEATR9

3.92e-039943217q12
CytobandEnsembl 112 genes in cytogenetic band chr7p15

PALS2 TAX1BP1

4.08e-03101432chr7p15
Cytoband20p13

FASTKD5 MAVS

4.16e-0310243220p13
CytobandEnsembl 112 genes in cytogenetic band chr20p13

FASTKD5 MAVS

5.98e-03123432chr20p13
CytobandEnsembl 112 genes in cytogenetic band chr3q22

UBA5 COL6A6

7.16e-03135432chr3q22
CytobandEnsembl 112 genes in cytogenetic band chr7q31

ZNF800 SPAM1

7.68e-03140432chr7q31
CytobandEnsembl 112 genes in cytogenetic band chr17q12

MYO19 HEATR9

8.66e-03149432chr17q12
GeneFamilyADAM metallopeptidase domain containing|CD molecules

FGFR1 CTLA4 TNFRSF11A CXCR1

3.01e-03394284471
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#4_top-relative-expression-ranked_1000

ZNF800 PANK3 PEG3 FGL2

2.99e-0590424gudmap_developingGonad_P2_epididymis_1000_k4
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_200

SAMD9L FMO2

5.70e-056422gudmap_kidney_adult_JuxtaGlom_Ren1_k4_200
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FGFR1 FMO2 TBX4 PEAK1 PEG3 EPHA3

3.37e-0819643654f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMOD COL6A6 SCG2 EPHA3

7.59e-07177435cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell356C-Fibroblasts-Fibroblast-C_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMOD COL6A6 SCG2 EPHA3

7.59e-07177435db222faaecbe5600da39277243c4e7e764eb63c9
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FGFR1 TBX4 LRCH2 PEG3 EPHA3

8.95e-0718343512daaea821e49bc94a01e2496331e92a80d27339
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FMO2 TBX4 PEAK1 PEG3 EPHA3

1.22e-06195435cbe518b465b4ef32797ae6b608219207c08493df
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 TBX4 PEAK1 PEG3

1.22e-061954356bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellPND03-Mesenchymal-Mesenchymal_structural|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FMO2 TBX4 PEAK1 PEG3 EPHA3

1.22e-06195435136b06b0931a69b1241101f68c01c44c70365fd9
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 TBX4 PEAK1 PEG3

1.22e-06195435a3b468125e48f072255cede7645f6692298ecf54
ToppCellE17.5-Mesenchymal|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FMO2 TBX4 PEAK1 PEG3 EPHA3

1.25e-06196435b4ee991445b612506372b9361ebfe72cb59b811e
ToppCellPND01-Mesenchymal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 TBX4 PEAK1 PEG3

1.29e-06197435292b8cc3dafddf5d323fe4e3d3ea5ac61e6ce027
ToppCellASK440-Epithelial-Type_1|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

FZD6 FMO2 PEAK1 GPRC5A SCG2

1.29e-061974351eda2c2504451a3d626dda5c2b2b12eeaa6bca54
ToppCellASK440-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

FZD6 FMO2 PEAK1 GPRC5A SCG2

1.29e-06197435782449c522c9e16e72bf999a73090688a3aefe06
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

FGFR1 TNFRSF11A FOXN3 FGL2

1.32e-0684434013cf97d08d0adb3697cf2a146ff5ca13c676f64
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

FMO2 FMO3 FMOD SCG2 EPHA3

1.35e-0619943512133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

FMO2 FMO3 TBX4 FMOD COL6A6

1.35e-061994357a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

FMO2 FMO3 TBX4 COL6A6 EPHA3

1.39e-06200435aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FMO2 FMO3 TBX4 COL6A6 EPHA3

1.39e-06200435a510deaada669e690329183e18df02870bd204b3
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 FMO3 TBX4 FMOD COL6A6

1.39e-06200435cb31cfcfa8e6d6cc610c4c22e97bc009dd8a9e7c
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FMO2 FMO3 TBX4 COL6A6 EPHA3

1.39e-06200435dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

SAMD9L LRCH2 EPHA3 FGL2

1.88e-05164434362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCellfacs-Trachea-nan-24m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC5B FMO3 FMO6P SCG2

2.21e-05171434d2a10e94b0490120d1420b944302eb841f902c64
ToppCell(03)_Secretory-(0)_uninjured|(03)_Secretory / shred by cell type and Timepoint

MUC5B FMO2 FMO3 FMO6P

2.37e-05174434ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMO3 FMOD COL6A6

2.53e-051774348220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMO3 FMOD COL6A6

2.53e-051774347617270f49cd6b7ba66db72d20560cee985012b2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF800 SAMD9L FMO2 TAX1BP1

2.59e-0517843401dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TNFRSF11A PEAK1 LRCH2 F8

2.59e-05178434ad3de3e03a401dac64431a541899445262246347
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FGFR1 FMO2 FMOD FGL2

2.83e-05182434e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TBX4 PEAK1 EPHA3

2.83e-05182434c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FGFR1 FMO2 FMO3 FMO6P

2.83e-051824348a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell(00)_Basal-(0)_uninjured|(00)_Basal / shred by cell type and Timepoint

MUC5B FMO2 FMO3 FMO6P

2.83e-05182434c02c9cab4389d80f318f4bb8d703c1e719672624
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO2 TBX4 PEAK1 EPHA3

2.83e-05182434dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FGFR1 FMO2 FMO3 FMO6P

2.83e-05182434e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX4 FMOD COL6A6 EPHA3

2.95e-05184434102b6f621a5b551e622f97b12d787c080b052a72
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

MUC5B FMO2 FMOD GPRC5A

3.14e-05187434be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

FZD6 FMO2 PEAK1 GPRC5A

3.14e-0518743477f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

FMO2 TBX4 PEAK1 EPHA3

3.21e-051884343f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FMO2 TBX4 FMOD COL6A6

3.41e-051914345271198116343c07202649889057e5774d7fdde3
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

FMO2 TBX4 PEAK1 PEG3

3.41e-05191434e7c605b56934d1383237c1f946dbccef25d91368
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEG3 EPHA3

3.41e-051914349f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell5'-Adult-LymphNode-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGFR1 FMO2 FMO3 COL6A6

3.41e-05191434054e9a79bd1486fd812bc7418fb091664fe3a646
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGFR1 FMO2 FMO3 COL6A6

3.48e-051924349479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCellPND14-Mesenchymal-Mesenchymal_structural|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.48e-0519243425492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell5'-Adult-LymphNode-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGFR1 FMO2 FMO3 COL6A6

3.48e-05192434d7faa993f68e530ad55185505384ae155d36c222
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.48e-05192434de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCellCOPD-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FMO2 FMO3 PEAK1 COL6A6

3.48e-0519243462904f94dfce430456f05066522cbf9bd29f4d7e
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TBX4 FMOD COL6A6 EPHA3

3.55e-051934343d85c28f6ebdcb15e875ad01d52d6c138fbf8525
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

FMO2 FMO3 TBX4 COL6A6

3.55e-051934345896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEG3 EPHA3

3.55e-05193434051f61156b0e2e95292b2d8377faf3190b50f264
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FMO2 PEAK1 PEG3 EPHA3

3.63e-05194434f15e81ff12525523c62d13105cf264ea72205e2e
ToppCelldroplet-Limb_Muscle-MUSCLE|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SAMD9L FOXN3 TAX1BP1 PEG3

3.63e-05194434e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell(5)_Fibroblast-C_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FMO2 FMO3 FMOD COL6A6

3.63e-0519443429a72e565c19407bbd198cfbc2a78106fe830d05
ToppCellControl-Stromal-Myofibroblast|Control / Disease state, Lineage and Cell class

FMO2 FMO3 TBX4 COL6A6

3.70e-05195434ffcf76cd72e43d8cf1058a49c76e0956065038bc
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-05195434b616ee6f1d878935d293c8e0a8bbc5b4385301f0
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-051954341c1135be421af98cd0077bec1ff2c4158d42aa21
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-051954343a0cad69cfc150a27a0666f612f5294c817197d7
ToppCellPND10-Mesenchymal-Mesenchymal_structural|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-0519543411d421bbbb71425d59cbdd673e052e00d5f0a768
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-051954342b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMO2 TBX4 FMOD COL6A6

3.70e-05195434df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMO2 TBX4 FMOD COL6A6

3.70e-051954344243190ad291d56694e2155954dbaa879c9d3844
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FGFR1 FMO2 FMO3 GPRC5A

3.70e-05195434fc43cd295f2cc3f6e9442232e028944f011c82cc
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C COL6A6 SCG2 PEG3

3.70e-051954343e519cffa6144a62b06124642a14c9ff39b76554
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-051954341f005ee1da66b539bd200aaa98f46edbbc7f12e4
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-0519543410f307aef8f4d9e71c501d5bcedb84d3be7a4d1b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C COL6A6 SCG2 PEG3

3.70e-051954347796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellPND07-Mesenchymal-Mesenchymal_structural|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 PEAK1 PEG3

3.70e-051954342f9a274b26fc528a85f50933ec2f4db1dc9da0ca
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FMO2 TBX4 PEG3 EPHA3

3.77e-05196434028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMO2 FMOD COL6A6 EPHA3

3.77e-051964349737a5f006d37b549f281e1863aca558e1e4dc99
ToppCellPND10-Mesenchymal|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FGFR1 FMO2 TBX4 PEAK1

3.77e-05196434ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FMO2 TBX4 PEAK1 EPHA3

3.77e-051964342a885eed52f9b002c7995e11e450c7e8d7ae69e6
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMO2 TBX4 FMOD COL6A6

3.77e-0519643442e9828222a9663525d571633e8a454c30bfa7f8
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FMO2 TBX4 PEAK1 EPHA3

3.77e-0519643414246f00c90741a5f8683f377e22e3a7c99661b9
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FMO2 TBX4 COL6A6 EPHA3

3.85e-0519743494a9603cbd3516fbcce871909693b88f20d41713
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGFR1 FOXN3 PEAK1 FGL2

3.85e-05197434e3349a381723393cd255f202afedd0c99037939b
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

FMO2 FMO3 FMOD COL6A6

3.85e-051974346c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCellSmart-seq2-thymus_(Smart-seq2)-myeloid-myeloid_macrophage-macrophage|thymus_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FGFR1 FOXN3 PEAK1 FGL2

3.85e-05197434e567886d69c6ea8dec87019c2ebc593793cb3107
ToppCellMild_COVID-19-Epithelial-Basal/Club|Mild_COVID-19 / Disease group,lineage and cell class ļ¼ˆ2021.01.30ļ¼‰

MUC5B FMO2 FMO3 GPRC5A

3.85e-051974344cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

KMT2C SAMD9L FOXN3 FGL2

3.93e-0519843461ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 FMO3 FMOD EPHA3

3.93e-05198434300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCelldistal-mesenchymal-Myofibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMOD SCG2 CHD5

3.93e-05198434beef5075ba6dcd4d0a447bc4e57efcaf2e93c546
ToppCellBronchus_Control_(B.)-Stromal-TX-Mesothelial-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FMO3 F8 PEG3 EPHA3

3.93e-051984349b1a58fcf818f9c4ae57bbe99655f0a64fe87df7
ToppCellE18.5-Mesenchymal|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FMO2 TBX4 PEAK1 PEG3

3.93e-05198434a16aa41eab2e297e56de43c22c355df0f79315da
ToppCellTracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 FMO3 TBX4 LRCH2

3.93e-0519843408d393853e195a7eacace454153e425a273e2d23
ToppCellCOPD-Stromal-Fibroblast|COPD / Disease state, Lineage and Cell class

FGFR1 FMO2 FMOD GPRC5A

3.93e-051984347904af61473cb20064f7a3a1e1bfe8d5913cf317
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.00e-0519943428c1722deef3b8347371c7359be7c64b95780de3
ToppCelldistal-mesenchymal-Alveolar_Fibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.00e-05199434fb23ecce41e31e2cc01814e3c0add756f489561f
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMO3 FMOD COL6A6

4.00e-05199434f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCelldistal-mesenchymal-Alveolar_Fibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.00e-05199434655d07cf9a2fd9b945a2ed4f824cba0297de72a8
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMO3 FMOD COL6A6

4.00e-051994349c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMO3 PEAK1 COL6A6

4.00e-05199434212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FMO2 FMO3 PEAK1 COL6A6

4.00e-0519943414b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellmedial-mesenchymal-Alveolar_Fibroblast|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.08e-05200434c22cbfecee00183dd4be678f116ab9fd9ad0a4dd
ToppCelldistal-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.08e-0520043412b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FGFR1 FMOD COL6A6 EPHA3

4.08e-05200434fee22a6a6c7b93af204b5b56f2c34f1411500e18
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 FMO3 FMOD COL6A6

4.08e-052004348c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TBX4 PEAK1 COL6A6 EPHA3

4.08e-052004348ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellmedial-2-mesenchymal-Alveolar_Fibroblast|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.08e-05200434cc6062dac07916c29091fc6bee2b864d29e6525b
ToppCellmedial-mesenchymal-Alveolar_Fibroblast-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.08e-052004345c0716bf375c8158f7dc2c82bf5eaf37af594dd0
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FMO2 FMO3 TBX4 COL6A6

4.08e-052004343dd022e974fec7013ba18f333da63f58fbf2dd7c
ToppCellBiopsy_IPF-Mesenchymal-Myofibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

TBX4 FMOD COL6A6 EPHA3

4.08e-05200434c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCelldistal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FMO2 FMO3 FMOD COL6A6

4.08e-0520043420112be28f80baffad92641c9cfd7c3718967dbb
DrugN,N-dimethylaniline-N-oxide

FMO2 FMO3 FMO6P

1.02e-0611433CID000000950
Drugmethyl p-tolyl sulfide

FMO2 FMO3 FMO6P

2.25e-0614433CID000069334
DrugS-benzyl-L-cysteine

FMO2 FMO3 FMO6P

1.24e-0524433CID000076454
Drugthiobenzamide

FMO2 FMO3 FMO6P

1.58e-0526433CID000683563
DrugBenzydamine

FMO2 FMO3

2.09e-054432ctd:D001591
DrugMoxisylyte hydrochoride [964-52-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A

FGFR1 CTLA4 SPAM1 FMOD SENP5

3.32e-051964357015_UP
Drugpioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A

FGFR1 FOXN3 PEAK1 TDRD1 EDRF1

3.40e-051974355925_UP
DrugCcris 2188

FMO2 FMO3

3.47e-055432CID000146896
Drug3-Acetamidocoumarin [779-30-6]; Down 200; 19.6uM; PC3; HT_HG-U133A

LMF1 FGFR1 KCNJ4 PEG3 SENP5

3.48e-051984354601_DN
DrugTroleandomycin [2751-09-9]; Down 200; 5uM; HL60; HG-U133A

FASTKD5 FOXN3 PANK3 MYO19 ANGEL1

3.56e-051994351965_DN
Drugn-octylamine

FMO2 FMO3 FMO6P

5.47e-0539433CID000008143
DrugN,N-dimethylaniline

FMO2 FMO3 FMO6P

6.84e-0542433CID000000949
DiseaseS-methylcysteine measurement

FMO3 FMO6P

1.98e-062422EFO_0800054
DiseaseLiver Diseases, Parasitic

KMT2C PEG3

7.08e-059422C0023897
DiseaseMyasthenia gravis

CTLA4 TNFRSF11A

1.53e-0413422EFO_0004991
Diseaselentiform nucleus measurement

FMO3 FMO6P

1.78e-0414422EFO_0004913
Diseasesquamous cell carcinoma (is_implicated_in)

KMT2C CTLA4

2.98e-0418422DOID:1749 (is_implicated_in)
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C PEG3

5.35e-0424422C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C PEG3

5.35e-0424422C3805278
Diseasepseudotumor cerebri

FOXN3 CXCR1

6.29e-0426422EFO_1001132
DiseaseCholangiocarcinoma

KMT2C PEG3

6.29e-0426422C0206698
DiseaseSezary Syndrome

KMT2C CTLA4

6.79e-0427422C0036920
DiseaseLarge cell carcinoma of lung

FGFR1 EPHA3

9.55e-0432422C0345958
DiseaseSquamous cell carcinoma of lung

FGFR1 EPHA3

9.55e-0432422C0149782

Protein segments in the cluster

PeptideGeneStartEntry
EAPPCKMTEPFNFEK

TDRD1

16

Q9BXT4
NYQRKNDMDEPPPFD

CHD5

541

Q8TDI0
PPSQPFFNEDQMKCV

MUC5B

1201

Q9HC84
QRNPMDYPVEDAFCK

GPRC5A

271

Q8NFJ5
PPPSAFCYENELALM

KCNJ4

366

P48050
DCPPNFPTAMYCDNR

FMOD

81

Q06828
NSSKEMMCFPDFPFP

FMO3

61

P31513
IPFYSSDLPCDFMQP

KMT2C

3451

Q8NEZ4
NSCREKEPSYPMPVQ

MAVS

131

Q7Z434
DEAQPCQPMDDAKYS

MYO19

316

Q96H55
CEETEDKYQNPFTMP

EDRF1

441

Q3B7T1
DPMDPNPCSATYSNL

PEAK1

1096

Q9H792
PCNIQMEDPTFKENY

F8

1921

P00451
NSSKEMMCFPDFPYP

FMO6P

61

O60774
KNQECEEAFMPSPTF

PEG3

536

Q9GZU2
RCQKMPFNLDDPYPL

PANK3

171

Q9H999
SKCYDSPPSSPEMNN

PALS2

101

Q9NZW5
CAPPCPNMYFKSDEL

FZD6

181

O60353
KMPEFNQYPEHLPTC

FASTKD5

461

Q7L8L6
SNVEFMCKVYSDPQP

FGFR1

271

P11362
SDMPYDARQNPNCKP

FOXN3

101

O00409
NFTGMPPADEDYSPC

CXCR1

16

P25024
CENNYFRADKDPPSM

EPHA3

306

P29320
PDPKNSSFEVYCDME

FGL2

231

Q14314
MSCFSDFPMPEDFPN

FMO2

66

Q99518
YVKMPPTEPECEKQF

CTLA4

201

P16410
PPMETEEPQIFYNAS

SPAM1

471

P38567
SCDQARPPPVQSYMD

COL6A6

1951

A6NMZ7
PSQPLTDSMEDFYPN

LRCH2

326

Q5VUJ6
PLCELMFPPNYDQSK

TAX1BP1

731

Q86VP1
VCPMCSEQFPPDYDQ

TAX1BP1

756

Q86VP1
LKPEQLTCMPYPFDQ

SAMD9L

156

Q8IVG5
FPPMYEENSRDNPFK

SCG2

166

P13521
PMQSEPQYADCAALP

ANGEL1

151

Q9UNK9
PKDPSCRHQPYFPDM

SENP5

296

Q96HI0
EMEFDPNSNPPCYKT

POLR2G

116

P62487
PNSNPPCYKTMDEDI

POLR2G

121

P62487
FFPTMSMKPNPQCDD

UBA5

291

Q9GZZ9
PLSCYQMPKEEFPPS

HEATR9

41

A2RTY3
EAFSYPQKQEPPEME

TRAPPC8

1271

Q9Y2L5
YCPPSLQMDDNLPDV

ZNF800

91

Q2TB10
PPYDQQMLSPSYCSE

TBX4

371

P57082
EEKTFPEDMCYPDQG

TNFRSF11A

291

Q9Y6Q6
TCPPMEVYESPFSEQ

GLDC

1001

P23378
TCMDFHYETQPMPNP

LMF1

236

Q96S06