Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	microtubule motor activity	DNAH14 KIF15 DNAH8 DYNC1H1 DNAH10 DNAH17 KIF13A KIF1C	6.34e-07	70	207	8	GO:0003777
GeneOntologyMolecularFunction	actin filament binding	SPTAN1 SPTBN1 GAS2 CLASP2 SPTBN5 EPS8L3 PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1 MYH15	7.54e-07	227	207	13	GO:0051015
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH14 DNAH8 DYNC1H1 DNAH10 DNAH17	8.76e-07	18	207	5	GO:0008569
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH14 SPTBN5 DNAH8 DYNC1H1 DNAH10 DNAH17	2.05e-06	37	207	6	GO:0045505
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH14 KIF15 DNAH8 DYNC1H1 DNAH10 DNAH17 MYH15 KIF13A KIF1C	3.92e-06	118	207	9	GO:0003774
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH14 DNAH8 DYNC1H1 DNAH10 DNAH17	9.23e-06	28	207	5	GO:0051959
GeneOntologyMolecularFunction	actin binding	MAP1A SPTAN1 SPTBN1 GAS2 CLASP2 SPTBN5 SYNE2 EPS8L3 DMD UTRN PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1 MYH15	1.11e-05	479	207	17	GO:0003779
GeneOntologyMolecularFunction	cytoskeletal protein binding	MAP1A SPTAN1 SPTBN1 HSPH1 GAS2 CLASP2 SPTBN5 EML5 KIF15 SYNE2 EPS8L3 DMD DNM1 UTRN PLS3 FLNB GAS2L3 SYNE1 CAPN3 EML3 SPTBN4 MACF1 MYH15 AATF KIF13A UNC13A KIF1C	2.78e-05	1099	207	27	GO:0008092
GeneOntologyMolecularFunction	ATP-dependent activity	HSPH1 DNAH14 MDN1 KIF15 SMPDL3A DNAH8 DYNC1H1 ABCC10 DNAH10 ATP13A5 BTAF1 NUBPL ATP8B2 DNAH17 MACF1 MYH15 KIF13A KIF1C	7.59e-05	614	207	18	GO:0140657
GeneOntologyMolecularFunction	cytoskeletal anchor activity	MAP1A GAS2 GAS2L3 SPTBN4	1.01e-04	24	207	4	GO:0008093
GeneOntologyMolecularFunction	superoxide-generating NADPH oxidase activator activity	NOXA1 NCF2 NCF4	1.25e-04	10	207	3	GO:0016176
GeneOntologyMolecularFunction	cell adhesion molecule binding	PDXDC1 SPTAN1 SPTBN1 SCYL1 ITGB4 TENM2 EPS15L1 FCER2 TJP2 DMD GCN1 UTRN FLNB GRIN2A GRIN2B PKP3 MACF1	1.77e-04	599	207	17	GO:0050839
GeneOntologyMolecularFunction	polyprenyltransferase activity	DHDDS COQ2	3.19e-04	3	207	2	GO:0002094
GeneOntologyMolecularFunction	microtubule binding	MAP1A GAS2 CLASP2 EML5 KIF15 DNM1 GAS2L3 EML3 MACF1 KIF13A KIF1C	3.88e-04	308	207	11	GO:0008017
GeneOntologyMolecularFunction	spectrin binding	SPTAN1 SPTBN5 SPTBN4 UNC13A	4.08e-04	34	207	4	GO:0030507
GeneOntologyMolecularFunction	stalled ribosome sensor activity	MAP3K20 GCN1	6.33e-04	4	207	2	GO:0170011
GeneOntologyMolecularFunction	ATP hydrolysis activity	MDN1 KIF15 SMPDL3A DNAH8 DYNC1H1 ABCC10 DNAH10 ATP13A5 BTAF1 ATP8B2 MACF1 KIF13A KIF1C	7.27e-04	441	207	13	GO:0016887
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE2 SYNE1	1.05e-03	5	207	2	GO:0140444
GeneOntologyMolecularFunction	protein-membrane adaptor activity	SYNE2 SYNE1 ATG2B SPTBN4	1.20e-03	45	207	4	GO:0043495
GeneOntologyMolecularFunction	phosphatidylcholine-sterol O-acyltransferase activator activity	APOA5 APOA1	1.56e-03	6	207	2	GO:0060228
GeneOntologyBiologicalProcess	negative regulation of protein depolymerization	MAP1A SPTAN1 SPTBN1 CLASP2 SPTBN5 CARMIL2 SPTBN4	2.90e-05	89	204	7	GO:1901880
GeneOntologyBiologicalProcess	regulation of short-term neuronal synaptic plasticity	UNC13B SLC8A2 RAB3GAP1 UNC13A	5.91e-05	22	204	4	GO:0048172
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	MAP1A SPTAN1 SPTBN1 CLASP2 SPTBN5 CARMIL2 SPTBN4	6.15e-05	100	204	7	GO:0043242
GeneOntologyBiologicalProcess	nucleus localization	SYNE2 DMD DYNC1H1 SYNE1 MTOR	7.15e-05	44	204	5	GO:0051647
GeneOntologyBiologicalProcess	regulation of protein depolymerization	MAP1A SPTAN1 SPTBN1 CLASP2 SPTBN5 CARMIL2 SPTBN4	8.38e-05	105	204	7	GO:1901879
GeneOntologyBiologicalProcess	actin filament capping	SPTAN1 SPTBN1 SPTBN5 CARMIL2 SPTBN4	8.88e-05	46	204	5	GO:0051693
GeneOntologyBiologicalProcess	regulation of cellular component size	SPTAN1 SPTBN1 FSTL4 CLASP2 SPTBN5 SLC12A9 DNM1 CARMIL2 SPTBN4 MTOR FSHR C1QTNF9 MACF1 RAB21	9.30e-05	426	204	14	GO:0032535
GeneOntologyBiologicalProcess	dense core granule docking	UNC13B UNC13A	9.73e-05	2	204	2	GO:0061790
GeneOntologyBiologicalProcess	positive regulation of inhibitory postsynaptic potential	UNC13B GRIN2A GRIN2B	1.09e-04	10	204	3	GO:0097151
GeneOntologyBiologicalProcess	dense core granule localization	BAIAP3 UNC13B UNC13A KIF1C	1.58e-04	28	204	4	GO:0032253
GeneOntologyBiologicalProcess	negative regulation of actin filament depolymerization	SPTAN1 SPTBN1 SPTBN5 CARMIL2 SPTBN4	1.61e-04	52	204	5	GO:0030835
GeneOntologyBiologicalProcess	regulation of neuronal synaptic plasticity	UNC13B GRIN2A GRIN2B SLC8A2 RAB3GAP1 UNC13A	1.74e-04	83	204	6	GO:0048168
GeneOntologyCellularComponent	supramolecular fiber	MAP1A SPTAN1 SPTBN1 HSPH1 GAS2 CLASP2 DNAH14 EML5 KIF15 SYNE2 SLMAP DMD DNM1 DNAH8 PLS3 DYNC1H1 FLNB DNAH10 GAS2L3 SYNE1 COL27A1 CAPN3 MYOM3 GRIN2B CCDC57 EML3 SPTBN4 SLC8A2 KRT75 RTL1 DNAH17 MACF1 MYH15 KIF13A KIF1C	6.76e-09	1179	209	35	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	MAP1A SPTAN1 SPTBN1 HSPH1 GAS2 CLASP2 DNAH14 EML5 KIF15 SYNE2 SLMAP DMD DNM1 DNAH8 PLS3 DYNC1H1 FLNB DNAH10 GAS2L3 SYNE1 COL27A1 CAPN3 MYOM3 GRIN2B CCDC57 EML3 SPTBN4 SLC8A2 KRT75 RTL1 DNAH17 MACF1 MYH15 KIF13A KIF1C	8.03e-09	1187	209	35	GO:0099081
GeneOntologyCellularComponent	spectrin	SPTAN1 SPTBN1 SPTBN5 SPTBN4	1.18e-06	9	209	4	GO:0008091
GeneOntologyCellularComponent	microtubule associated complex	MAP1A DNAH14 SPTBN5 KIF15 DNAH8 DYNC1H1 DNAH10 DNAH17 KIF13A KIF1C	5.26e-06	161	209	10	GO:0005875
GeneOntologyCellularComponent	microtubule	MAP1A HSPH1 CLASP2 DNAH14 EML5 KIF15 DNM1 DNAH8 DYNC1H1 DNAH10 GAS2L3 CCDC57 EML3 SLC8A2 DNAH17 MACF1 KIF13A KIF1C	7.39e-06	533	209	18	GO:0005874
GeneOntologyCellularComponent	myofibril	SPTAN1 SPTBN1 SYNE2 SLMAP DMD FLNB SYNE1 CAPN3 MYOM3 GRIN2B RTL1 MYH15	2.08e-05	273	209	12	GO:0030016
GeneOntologyCellularComponent	polymeric cytoskeletal fiber	MAP1A HSPH1 GAS2 CLASP2 DNAH14 EML5 KIF15 DMD DNM1 DNAH8 PLS3 DYNC1H1 DNAH10 GAS2L3 CCDC57 EML3 SPTBN4 SLC8A2 KRT75 DNAH17 MACF1 KIF13A KIF1C	3.61e-05	899	209	23	GO:0099513
GeneOntologyCellularComponent	contractile muscle fiber	SPTAN1 SPTBN1 SYNE2 SLMAP DMD FLNB SYNE1 CAPN3 MYOM3 GRIN2B RTL1 MYH15	3.76e-05	290	209	12	GO:0043292
GeneOntologyCellularComponent	sarcomere	SPTAN1 SPTBN1 SYNE2 SLMAP DMD FLNB SYNE1 CAPN3 MYOM3 GRIN2B RTL1	4.41e-05	249	209	11	GO:0030017
GeneOntologyCellularComponent	Z disc	SPTAN1 SYNE2 SLMAP DMD FLNB CAPN3 GRIN2B RTL1	1.43e-04	151	209	8	GO:0030018
GeneOntologyCellularComponent	dynein complex	DNAH14 DNAH8 DYNC1H1 DNAH10 DNAH17	2.02e-04	54	209	5	GO:0030286
GeneOntologyCellularComponent	filopodium	RIPOR2 TENM2 SYNE2 DMD UTRN DYNC1H1 OSBPL3	2.41e-04	123	209	7	GO:0030175
GeneOntologyCellularComponent	synaptic membrane	GRIPAP1 HTR3C ITGB4 TENM2 DMD DNM1 UTRN UNC13B COL13A1 SYNE1 CNKSR2 GRIN2A GRIN2B SLC8A2 UNC13A GABRA6	2.69e-04	583	209	16	GO:0097060
GeneOntologyCellularComponent	I band	SPTAN1 SYNE2 SLMAP DMD FLNB CAPN3 GRIN2B RTL1	2.73e-04	166	209	8	GO:0031674
GeneOntologyCellularComponent	leading edge membrane	RIPOR2 SPTBN1 CLASP2 BMX SYNE2 EPS8L3 GRIN2A MACF1 GABRA6	2.74e-04	210	209	9	GO:0031256
GeneOntologyCellularComponent	cell leading edge	RIPOR2 SPTBN1 CLASP2 ITGB4 BMX SYNE2 EPS8L3 PLD1 DMD CARMIL2 APBB2 GRIN2A MACF1 GABRA6	5.34e-04	500	209	14	GO:0031252
GeneOntologyCellularComponent	axon	GRIPAP1 MAP1A SPTAN1 SPTBN1 CLASP2 TENM2 RXRA DMD DNM1 DYNC1H1 UNC13B APBB2 GRIN2A GRIN2B SPTBN4 SLC8A2 RAB21 UNC13A UNC80 KIF1C	6.46e-04	891	209	20	GO:0030424
GeneOntologyCellularComponent	NADPH oxidase complex	NOXA1 NCF2 NCF4	7.20e-04	18	209	3	GO:0043020
GeneOntologyCellularComponent	postsynaptic membrane	HTR3C ITGB4 TENM2 DMD UTRN COL13A1 SYNE1 CNKSR2 GRIN2A GRIN2B SLC8A2 GABRA6	8.16e-04	405	209	12	GO:0045211
GeneOntologyCellularComponent	cytoplasmic region	MAP1A CLASP2 SPTBN5 DNAH8 DYNC1H1 UNC13B DNAH10 DNAH17 RAB21 UNC13A KIF1C	1.05e-03	360	209	11	GO:0099568
GeneOntologyCellularComponent	cell cortex region	CLASP2 SPTBN5 UNC13B UNC13A	1.05e-03	45	209	4	GO:0099738
GeneOntologyCellularComponent	filopodium membrane	SYNE2 DMD UTRN	1.15e-03	21	209	3	GO:0031527
GeneOntologyCellularComponent	cell cortex	SPTAN1 SPTBN1 CLASP2 ITGB4 SPTBN5 DYNC1H1 UNC13B FLNB SPTBN4 MACF1 UNC13A	1.33e-03	371	209	11	GO:0005938
GeneOntologyCellularComponent	postsynapse	GRIPAP1 MAP1A SPTAN1 SPTBN1 HTR3C ITGB4 TENM2 CASKIN1 DMD CPSF2 UTRN COL13A1 SYNE1 CNKSR2 GRIN2A GRIN2B SLC8A2 RAB3GAP1 MTOR MACF1 GABRA6	1.37e-03	1018	209	21	GO:0098794
GeneOntologyCellularComponent	cell projection membrane	RIPOR2 SPTBN1 CLASP2 BBS9 BMX SYNE2 EPS8L3 DMD UTRN GRIN2A MACF1 GABRA6	1.39e-03	431	209	12	GO:0031253
GeneOntologyCellularComponent	axonemal dynein complex	DNAH8 DNAH10 DNAH17	1.93e-03	25	209	3	GO:0005858
GeneOntologyCellularComponent	main axon	MAP1A SPTAN1 SPTBN1 DNM1 SPTBN4	2.00e-03	89	209	5	GO:0044304
GeneOntologyCellularComponent	dendritic branch	MAP1A GRIN2B	2.02e-03	7	209	2	GO:0044307
GeneOntologyCellularComponent	actin cytoskeleton	SPTAN1 RGS22 SPTBN1 GAS2 SPTBN5 PLS3 CCDC102A FLNB CARMIL2 GAS2L3 SPTBN4 MACF1 MYH15 EPHA3	2.05e-03	576	209	14	GO:0015629
GeneOntologyCellularComponent	late endosome membrane	SLC9A9 VPS13C WDR81 PLD1 BAIAP3 ATP13A5 AP5M1	2.20e-03	179	209	7	GO:0031902
GeneOntologyCellularComponent	phagolysosome	NCF2 NCF4	2.68e-03	8	209	2	GO:0032010
HumanPheno	Hyperlordosis	MAP3K20 SYNE2 TONSL GTF2IRD2 DMD FLNB SYNE1 COL27A1 GNPTAB CAPN3 RAB3GAP1 GTF2I FUCA1 VPS13B	8.01e-06	222	81	14	HP:0003307
HumanPheno	Lordosis	MAP3K20 SYNE2 TONSL GTF2IRD2 DMD FLNB SYNE1 COL27A1 GNPTAB CAPN3 RAB3GAP1 GTF2I FUCA1 VPS13B	8.01e-06	222	81	14	HP:0002939
HumanPheno	Tip-toe gait	SPTBN1 SYNE2 DMD DYNC1H1 COL13A1 SYNE1 GNPTAB CAPN3 KIF1C	1.13e-05	91	81	9	HP:0030051
MousePheno	abnormal synapse morphology	MNX1 SCYL1 EPS15L1 SYNE2 DMD DNM1 UTRN DYNC1H1 UNC13B COL13A1 SYNE1 THOC2 UNC13A	3.29e-06	224	169	13	MP:0009538
Domain	ACTININ_2	SPTBN1 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB SYNE1 SPTBN4 MACF1	2.16e-14	23	206	10	PS00020
Domain	ACTININ_1	SPTBN1 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB SYNE1 SPTBN4 MACF1	2.16e-14	23	206	10	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB SYNE1 SPTBN4 MACF1	2.16e-14	23	206	10	IPR001589
Domain	Spectrin	SPTAN1 SPTBN1 SPTBN5 SYNE2 DMD UTRN SYNE1 SPTBN4 MACF1	1.45e-12	23	206	9	PF00435
Domain	CH	SPTBN1 GAS2 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1	5.67e-12	65	206	12	SM00033
Domain	CH	SPTBN1 GAS2 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1	1.43e-11	70	206	12	PF00307
Domain	Spectrin_repeat	SPTAN1 SPTBN1 SPTBN5 SYNE2 DMD UTRN SYNE1 SPTBN4 MACF1	1.68e-11	29	206	9	IPR002017
Domain	-	SPTBN1 GAS2 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1	1.70e-11	71	206	12	1.10.418.10
Domain	CH	SPTBN1 GAS2 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1	2.40e-11	73	206	12	PS50021
Domain	CH-domain	SPTBN1 GAS2 SPTBN5 SYNE2 DMD UTRN PLS3 FLNB GAS2L3 SYNE1 SPTBN4 MACF1	3.34e-11	75	206	12	IPR001715
Domain	SPEC	SPTAN1 SPTBN1 SPTBN5 SYNE2 DMD UTRN SYNE1 SPTBN4 MACF1	4.57e-11	32	206	9	SM00150
Domain	Spectrin/alpha-actinin	SPTAN1 SPTBN1 SPTBN5 SYNE2 DMD UTRN SYNE1 SPTBN4 MACF1	4.57e-11	32	206	9	IPR018159
Domain	-	RIPOR2 SCYL1 CLASP2 NCAPG TELO2 GCN1 RTTN BTAF1 HEATR1 MROH6 MTOR PKP3 PRKDC AP4B1 STAG3 SYMPK	3.48e-09	222	206	16	1.25.10.10
Domain	HEAT	SCYL1 CLASP2 NCAPG GCN1 BTAF1 HEATR1 MTOR PRKDC SYMPK	1.35e-08	58	206	9	IPR000357
Domain	HEAT	SCYL1 CLASP2 NCAPG GCN1 BTAF1 HEATR1 PRKDC SYMPK	4.94e-08	48	206	8	PF02985
Domain	ARM-like	RIPOR2 SCYL1 CLASP2 NCAPG TELO2 GCN1 RTTN BTAF1 HEATR1 MROH6 MTOR PKP3 PRKDC AP4B1 STAG3 SYMPK	5.55e-08	270	206	16	IPR011989
Domain	HEAT_REPEAT	SCYL1 CLASP2 NCAPG GCN1 BTAF1 HEATR1 MTOR PRKDC	1.00e-06	70	206	8	PS50077
Domain	ARM-type_fold	RIPOR2 SCYL1 CLASP2 NCAPG TELO2 GCN1 RTTN BTAF1 HEATR1 MROH6 MTOR PKP3 PRKDC AP4B1 STAG3 SYMPK	1.19e-06	339	206	16	IPR016024
Domain	-	GTF2IRD2 GTF2IRD2B GTF2I	5.25e-06	4	206	3	3.90.1460.10
Domain	GTF2I	GTF2IRD2 GTF2IRD2B GTF2I	5.25e-06	4	206	3	PS51139
Domain	GTF2I	GTF2IRD2 GTF2IRD2B GTF2I	5.25e-06	4	206	3	PF02946
Domain	GTF2I	GTF2IRD2 GTF2IRD2B GTF2I	5.25e-06	4	206	3	IPR004212
Domain	Munc13_dom-2	BAIAP3 UNC13B UNC13A	1.30e-05	5	206	3	IPR014772
Domain	MHD2	BAIAP3 UNC13B UNC13A	1.30e-05	5	206	3	PS51259
Domain	Munc13_subgr_dom-2	BAIAP3 UNC13B UNC13A	1.30e-05	5	206	3	IPR019558
Domain	Autophagy-rel_C	VPS13C ATG2B VPS13B	1.30e-05	5	206	3	IPR015412
Domain	ATG_C	VPS13C ATG2B VPS13B	1.30e-05	5	206	3	PF09333
Domain	Membr_traf_MHD	BAIAP3 UNC13B UNC13A	1.30e-05	5	206	3	PF10540
Domain	Dynein_heavy_chain_D4_dom	DNAH14 DNAH8 DYNC1H1 DNAH10	1.32e-05	14	206	4	IPR024317
Domain	Dynein_HC_stalk	DNAH14 DNAH8 DYNC1H1 DNAH10	1.32e-05	14	206	4	IPR024743
Domain	ATPase_dyneun-rel_AAA	MDN1 DNAH8 DYNC1H1 DNAH10	1.32e-05	14	206	4	IPR011704
Domain	MT	DNAH14 DNAH8 DYNC1H1 DNAH10	1.32e-05	14	206	4	PF12777
Domain	AAA_8	DNAH14 DNAH8 DYNC1H1 DNAH10	1.32e-05	14	206	4	PF12780
Domain	AAA_5	MDN1 DNAH8 DYNC1H1 DNAH10	1.32e-05	14	206	4	PF07728
Domain	DHC_fam	DNAH14 DNAH8 DYNC1H1 DNAH10	1.78e-05	15	206	4	IPR026983
Domain	Dynein_heavy	DNAH14 DNAH8 DYNC1H1 DNAH10	1.78e-05	15	206	4	PF03028
Domain	Dynein_heavy_dom	DNAH14 DNAH8 DYNC1H1 DNAH10	1.78e-05	15	206	4	IPR004273
Domain	EF-hand-dom_pair	FSTL5 SPTAN1 FSTL4 TBC1D9 EPS15L1 DMD UTRN PLS3 GNPTAB CAPN3 CAPNS2 MACF1 KCNIP4	1.90e-05	287	206	13	IPR011992
Domain	GAR	GAS2 GAS2L3 MACF1	2.58e-05	6	206	3	PS51460
Domain	GAS2	GAS2 GAS2L3 MACF1	2.58e-05	6	206	3	PF02187
Domain	-	GAS2 GAS2L3 MACF1	2.58e-05	6	206	3	3.30.920.20
Domain	GAS_dom	GAS2 GAS2L3 MACF1	2.58e-05	6	206	3	IPR003108
Domain	GAS2	GAS2 GAS2L3 MACF1	2.58e-05	6	206	3	SM00243
Domain	-	FSTL5 SPTAN1 FSTL4 TBC1D9 EPS15L1 DMD UTRN PLS3 CAPN3 CAPNS2 MACF1 KCNIP4	3.45e-05	261	206	12	1.10.238.10
Domain	Munc13_1	BAIAP3 UNC13B UNC13A	4.48e-05	7	206	3	IPR014770
Domain	MHD1	BAIAP3 UNC13B UNC13A	4.48e-05	7	206	3	PS51258
Domain	DUF1041	BAIAP3 UNC13B UNC13A	4.48e-05	7	206	3	PF06292
Domain	CAPS_dom	BAIAP3 UNC13B UNC13A	4.48e-05	7	206	3	IPR010439
Domain	EF-hand_1	FSTL5 SPTAN1 FSTL4 EPS15L1 PLS3 GNPTAB CAPNS2 MACF1 KCNIP4	4.88e-05	152	206	9	PF00036
Domain	EF_HAND_2	FSTL5 SPTAN1 FSTL4 TBC1D9 EPS15L1 PLS3 GNPTAB CAPN3 CAPNS2 MACF1 KCNIP4	5.35e-05	231	206	11	PS50222
Domain	EF_hand_dom	FSTL5 SPTAN1 FSTL4 TBC1D9 EPS15L1 PLS3 GNPTAB CAPN3 CAPNS2 MACF1 KCNIP4	5.56e-05	232	206	11	IPR002048
Domain	Chorein_N	VPS13C ATG2B VPS13B	7.11e-05	8	206	3	PF12624
Domain	DHC_N1	DNAH8 DYNC1H1 DNAH10	7.11e-05	8	206	3	PF08385
Domain	VPS13_N	VPS13C ATG2B VPS13B	7.11e-05	8	206	3	IPR026854
Domain	Dynein_heavy_dom-1	DNAH8 DYNC1H1 DNAH10	7.11e-05	8	206	3	IPR013594
Domain	Quino_amine_DH_bsu	FSTL5 FSTL4 TENM2 LRRK1	9.00e-05	22	206	4	IPR011044
Domain	EF_HAND_1	FSTL5 SPTAN1 FSTL4 EPS15L1 PLS3 GNPTAB CAPN3 CAPNS2 MACF1 KCNIP4	9.22e-05	204	206	10	PS00018
Domain	PH_dom-spectrin-type	SPTBN1 SPTBN5 SPTBN4	1.06e-04	9	206	3	IPR001605
Domain	Dystrophin	DMD UTRN	1.21e-04	2	206	2	IPR016344
Domain	EF_Hand_1_Ca_BS	FSTL5 SPTAN1 FSTL4 EPS15L1 PLS3 GNPTAB CAPN3 MACF1 KCNIP4	1.44e-04	175	206	9	IPR018247
Domain	PH	SPTBN1 SPTBN5 BMX AFAP1L2 OSBPL7 PLD1 DNM1 CNKSR2 SPTBN4 OSBPL3	2.37e-04	229	206	10	PF00169
Domain	SMAD_FHA_domain	IRF3 IRF4 SLMAP KIF13A KIF1C	2.65e-04	52	206	5	IPR008984
Domain	PH_dom-like	SPTBN1 RGPD1 SPTBN5 BMX AFAP1L2 OSBPL7 EPS8L3 PLD1 DNM1 ANKS1A APBB2 CNKSR2 SPTBN4 OSBPL3	2.84e-04	426	206	14	IPR011993
Domain	LRR_6	FBXL5 TONSL NLRC5 CARMIL2 NLRP14	3.46e-04	55	206	5	PF13516
Domain	NMDAR2_C	GRIN2A GRIN2B	3.61e-04	3	206	2	PF10565
Domain	Apolipoprotein	APOA5 APOA1	3.61e-04	3	206	2	PF01442
Domain	Unc-13	UNC13B UNC13A	3.61e-04	3	206	2	IPR027080
Domain	NMDAR2_C	GRIN2A GRIN2B	3.61e-04	3	206	2	IPR018884
Domain	ApoA_E	APOA5 APOA1	3.61e-04	3	206	2	IPR000074
Domain	-	SPTBN1 RGPD1 SPTBN5 BMX AFAP1L2 OSBPL7 PLD1 DNM1 ANKS1A APBB2 CNKSR2 SPTBN4 OSBPL3	4.19e-04	391	206	13	2.30.29.30
Domain	Dynein_heavy_dom-2	DNAH8 DYNC1H1 DNAH10	4.40e-04	14	206	3	IPR013602
Domain	DHC_N2	DNAH8 DYNC1H1 DNAH10	4.40e-04	14	206	3	PF08393
Domain	PB1	NOXA1 NCF2 NCF4	4.40e-04	14	206	3	SM00666
Domain	PB1	NOXA1 NCF2 NCF4	4.40e-04	14	206	3	PF00564
Domain	PB1	NOXA1 NCF2 NCF4	4.40e-04	14	206	3	PS51745
Domain	PB1_dom	NOXA1 NCF2 NCF4	4.40e-04	14	206	3	IPR000270
Domain	KASH	SYNE2 SYNE1	7.16e-04	4	206	2	IPR012315
Domain	SHR-BD	VPS13C VPS13B	7.16e-04	4	206	2	IPR009543
Domain	KASH	SYNE2 SYNE1	7.16e-04	4	206	2	PS51049
Domain	Spectrin_bsu	SPTBN1 SPTBN4	7.16e-04	4	206	2	IPR016343
Domain	KASH	SYNE2 SYNE1	7.16e-04	4	206	2	SM01249
Domain	KASH	SYNE2 SYNE1	7.16e-04	4	206	2	PF10541
Domain	VPS13_C	VPS13C VPS13B	7.16e-04	4	206	2	PF16909
Domain	VPS13_C	VPS13C VPS13B	7.16e-04	4	206	2	IPR031645
Domain	SHR-BD	VPS13C VPS13B	7.16e-04	4	206	2	PF06650
Domain	PH	SPTBN1 SPTBN5 BMX AFAP1L2 OSBPL7 PLD1 DNM1 CNKSR2 SPTBN4 OSBPL3	1.07e-03	278	206	10	SM00233
Domain	PH_DOMAIN	SPTBN1 SPTBN5 BMX AFAP1L2 OSBPL7 PLD1 DNM1 CNKSR2 SPTBN4 OSBPL3	1.10e-03	279	206	10	PS50003
Domain	PH_domain	SPTBN1 SPTBN5 BMX AFAP1L2 OSBPL7 PLD1 DNM1 CNKSR2 SPTBN4 OSBPL3	1.13e-03	280	206	10	IPR001849
Domain	P-loop_NTPase	DNAH14 MDN1 KIF15 TJP2 NLRC5 DNM1 DNAH8 DYNC1H1 ABCC10 DNAH10 BTAF1 LRRK1 NUBPL PAPSS2 TRIM23 NLRP14 MYH15 RAB21 KIF13A KIF1C	1.16e-03	848	206	20	IPR027417
Domain	FATC	MTOR PRKDC	1.18e-03	5	206	2	PF02260
Domain	DUF1041	UNC13B UNC13A	1.18e-03	5	206	2	SM01145
Domain	TPR-contain_dom	NOXA1 RGPD1 NCF2 PRPF6 TOMM70 TONSL PRKDC	1.40e-03	150	206	7	IPR013026
Domain	DUF3669_Znf	ZNF398 ZNF783	1.76e-03	6	206	2	IPR022137
Domain	Kinesin_assoc	KIF13A KIF1C	1.76e-03	6	206	2	PF16183
Domain	DUF3669	ZNF398 ZNF783	1.76e-03	6	206	2	PF12417
Domain	HELP	EML5 EML3	1.76e-03	6	206	2	PF03451
Domain	FAT	MTOR PRKDC	1.76e-03	6	206	2	PS51189
Domain	FATC	MTOR PRKDC	1.76e-03	6	206	2	PS51190
Domain	Kinesin_assoc	KIF13A KIF1C	1.76e-03	6	206	2	IPR032405
Domain	FAT	MTOR PRKDC	1.76e-03	6	206	2	PF02259
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTAN1 SPTBN1 SPTBN5 SPTBN4	2.73e-06	10	154	4	MM15112
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTAN1 SPTBN1 ITGB4 SPTBN5 PLS3 FLNB SPTBN4	7.96e-12	18	210	7	12119179
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDXDC1 DENND4A USP11 PSMD8 CLASP2 PRPF6 NCAPG TELO2 TONSL SLMAP TJP2 CPSF2 GCN1 PLS3 DYNC1H1 ANKS1A CUL1 POLE CNKSR2 HEATR1 LRRK1 PAPSS2 EML3 STK16 IBTK GTF2I OSBPL3 KCNIP4 AKAP11 AP4B1	2.50e-10	1284	210	30	17353931
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	PDXDC1 SPTAN1 SPTBN1 HSPH1 PSMD8 CLASP2 PRPF6 NCAPG MDN1 TELO2 GCN1 PLS3 DYNC1H1 CUL1 FLNB HEATR1 THOC2 GTF2I MTOR PRKDC SYMPK	3.98e-10	638	210	21	33239621
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP11 SPTAN1 SPTBN1 PRPF6 MDN1 PRMT5 SYNE2 TJP2 GCN1 UTRN DYNC1H1 FLNB POLE HEATR1 THOC2 GTF2I MTOR MACF1 AATF PRKDC SYMPK	6.04e-10	653	210	21	22586326
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DENND4A SPTAN1 SPTBN1 MAP3K20 CLASP2 CDCA2 BMX MDN1 PRMT5 SYNE2 TJP2 UTRN CCDC102A ANKS1A CARMIL2 MTOR OSBPL3 MACF1 AKAP11 CRYBG3 RAB21 KIF13A KIF1C	3.09e-09	861	210	23	36931259
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PDXDC1 GRIPAP1 USP11 SPTAN1 SPTBN1 HSPH1 SCYL1 PSMD8 EPS15L1 NCAPG KIF15 TELO2 PRMT5 TJP2 DNM1 GCN1 PLS3 DYNC1H1 ANKS1A CUL1 FLNB PAPSS2 RAB3GAP1 TRNT1 GTF2I OXCT1 MTOR MACF1 PRKDC KIF13A	4.57e-09	1455	210	30	22863883
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SPTAN1 SPTBN1 RGPD1 WDR81 CLASP2 TENM2 EPS15L1 MDN1 KIF15 CASKIN1 SYNE2 CPSF2 DNM1 DYNC1H1 ANKS1A SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 MTOR OSBPL3 MACF1 UNC13A	5.27e-09	963	210	24	28671696
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	GRIPAP1 SPTAN1 SPTBN1 SCYL1 PSMD8 EPS15L1 SLMAP TJP2 UTRN MAP4K2 DYNC1H1 FLNB BTAF1 MACF1 PRKDC	6.33e-09	360	210	15	33111431
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	RIPOR2 ERCC5 SPTBN1 HSPH1 DHDDS CLASP2 ITGB4 EML5 TJP2 PLD1 CPSF2 BAIAP3 UTRN FLNB GAS2L3 HEATR1 THOC2 TRNT1 OSBPL3 ITPRIP MACF1 AATF KLHDC10 KIF13A VPS13B	1.15e-08	1084	210	25	11544199
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	DENND4A ERCC5 SPTAN1 SPTBN1 HSPH1 RGPD1 PSMD8 PRPF6 CDCA2 SPCS3 MDN1 SYNE2 GTF2IRD2 DMD DNAH8 FLNB SYNE1 HEATR1 TEX14 CCDC57 SPTBN4 GTF2IRD2B TRNT1 KRT75 MACF1 MYH15 AATF PRKDC RAB21	1.47e-08	1442	210	29	35575683
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CLASP2 ITGB4 TBC1D9 EPS15L1 MDN1 CASKIN1 ZNF398 NLRC5 GCN1 DYNC1H1 ABCC10 UNC13B MRPL21 POLE RTTN MYOM3 BTAF1 LRRK1 NUBPL EML3 MROH6 MTOR FURIN PRKDC SYMPK	1.67e-08	1105	210	25	35748872
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MAP1A SPTAN1 SPTBN1 RGPD1 CLASP2 EPS15L1 CASKIN1 TJP2 CNKSR2 GRIN2A GRIN2B MACF1	1.94e-08	231	210	12	16452087
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	SPTAN1 PGM3 SPTBN5 PRMT5 SYNE2 DMD DNAH8 DNAH10 SYNE1 RTTN APBB2	2.15e-08	187	210	11	26460568
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	SPTAN1 SPTBN1 MRC2 DMD UTRN DYNC1H1 SYNE1 GNPTAB CNKSR2 MACF1	3.11e-08	151	210	10	17043677
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PDXDC1 USP11 VPS13C SCYL1 SPTBN5 TOMM70 SPCS3 MDN1 TELO2 SYNE2 SLMAP ALAS1 CUL1 MRPL21 SYNE1 POLE ATG2B HEATR1 TARS2 NUBPL IBTK RAB3GAP1 OXCT1 OSBPL3 AATF AKAP11 WDR41 CRYBG3 VPS13B	3.25e-08	1496	210	29	32877691
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DENND4A VPS13C SPTAN1 RGS22 SPTBN1 HSPH1 PSMD8 CLASP2 PRPF6 CDCA2 TOMM70 NCAPG MDN1 PRMT5 GCN1 PLS3 DYNC1H1 CUL1 FLNB DNAH10 SYNE1 POLE HEATR1 TARS2 THOC2 GTF2I MTOR PRKDC	4.34e-08	1425	210	28	30948266
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	SPTAN1 SPTBN1 CASKIN1 DNM1 DYNC1H1 ANKS1A SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 MACF1	4.85e-08	251	210	12	27507650
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	CENPB SPTAN1 SPTBN1 HSPH1 PRPF6 PGM3 TOMM70 NCAPG MDN1 TELO2 PRMT5 SYNE2 TJP2 GCN1 PLS3 DYNC1H1 CUL1 COG2 FLNB BTAF1 HEATR1 NUBPL THOC2 RAB3GAP1 GTF2I OXCT1 MTOR PRKDC	5.40e-08	1440	210	28	30833792
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	SPTAN1 HSPH1 CDCA2 EPS15L1 KIF15 GCN1 DYNC1H1 FLNB ATG2B HEATR1 GTF2I PRKDC	6.02e-08	256	210	12	33397691
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DENND4A MAP1A RGPD1 CLASP2 UTRN ANKS1A ATG2B IBTK MACF1 AKAP11 CRYBG3	6.72e-08	209	210	11	36779422
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	SPTAN1 SPTBN1 PRPF6 MDN1 PRMT5 GCN1 DYNC1H1 BTAF1 GTF2I PKP3 PRKDC STAG3	1.16e-07	272	210	12	31010829
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SPTAN1 SPTBN1 PRPF6 NCAPG MDN1 CPSF2 GCN1 DYNC1H1 FLNB EML3 GTF2I PRKDC SYMPK	1.36e-07	332	210	13	32786267
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	MAP1A SPTAN1 SPTBN1 DNM1 DYNC1H1 SYNE1 CNKSR2 GRIN2A GRIN2B MTOR MACF1 AKAP11	1.65e-07	281	210	12	28706196
Pubmed	Expanding the Interactome of TES by Exploiting TES Modules with Different Subcellular Localizations.	SPTAN1 SPTBN1 SCYL1 GCN1 UTRN DYNC1H1 FLNB RAB3GAP1 ITPRIP MACF1 PRKDC	2.19e-07	235	210	11	28378594
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 GRIPAP1 VPS13C SCYL1 CLASP2 CDCA2 EPS15L1 TJP2 PLD1 GCN1 DYNC1H1 APBB2 CNKSR2 TRIM23 GTF2I FURIN WDR41 PRKDC RAB21	3.02e-07	777	210	19	35844135
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	SPTAN1 SPTBN1 HSPH1 PRPF6 ITGB4 TJP2 DMD GCN1 PLS3 DYNC1H1 FLNB GTF2I KRT75 MACF1 PRKDC	3.34e-07	488	210	15	31324722
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	GRIPAP1 HSPH1 TBC1D9 PDZRN4 COL27A1 GNPTAB ATP8B2 RAB3GAP1 OSBPL3 DNAH17 MACF1 KLHDC10 RAB21 UNC80 KIF1C	3.80e-07	493	210	15	15368895
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MAP1A USP11 MDN1 UTRN DYNC1H1 MACF1 PRKDC	4.07e-07	76	210	7	27542412
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	CENPB VPS13C WDR81 EPS15L1 AFAP1L2 TELO2 PLD1 UTRN MAP4K2 CUL1 SYNE1 RTTN CNKSR2 BTAF1 OSBPL3 ITPRIP MACF1 KIF13A	4.48e-07	719	210	18	35337019
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	GRIPAP1 KCNH7 MAP1A SPTAN1 SPTBN1 RGPD1 PLPPR3 TENM2 EPS15L1 CASKIN1 TJP2 GCN1 FLNB ATG2B CNKSR2 GRIN2A GRIN2B RAB3GAP1 OXCT1 MACF1 CRYBG3 RAB21 UNC13A	4.81e-07	1139	210	23	36417873
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	DENND4A SPTBN1 MAP3K20 PRMT5 TJP2 DYNC1H1 ANKS1A CAPN3 EML3 OSBPL3 PRKDC	4.94e-07	255	210	11	15324660
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	PDXDC1 SPTAN1 SPTBN1 HSPH1 WDR81 TOMM70 MDN1 PRMT5 TONSL GCN1 UTRN DYNC1H1 CUL1 FLNB COL13A1 SYNE1 PAPSS2 MACF1 PRKDC	5.34e-07	807	210	19	30575818
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	PDXDC1 USP11 PSMD8 PGM3 TOMM70 TELO2 TJP2 DMD GCN1 UTRN PLS3 FLNB POLE DUSP6 APOA1 HEATR1 GTF2I MTOR OSBPL3 PKP3 PRKDC	5.50e-07	974	210	21	28675297
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	PDXDC1 USP11 HSPH1 RGPD1 PSMD8 PRPF6 PGM3 TOMM70 SPCS3 MDN1 TELO2 YAE1 PRMT5 CPSF2 GCN1 DYNC1H1 CUL1 POLE BTAF1 TARS2 THOC2 GTF2I WDR41 PRKDC	7.22e-07	1257	210	24	37317656
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	GRIPAP1 SPTAN1 SPTBN1 DMD DYNC1H1 SYNE1 APBB2 MACF1	7.28e-07	120	210	8	31413325
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	PRPF6 TELO2 GCN1 BTAF1 HEATR1 GTF2I MTOR PRKDC	7.28e-07	120	210	8	27320910
Pubmed	Evolution of general transcription factors.	GTF2IRD2 GTF2IRD2B GTF2I	8.64e-07	4	210	3	23229069
Pubmed	GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.	GTF2IRD2 GTF2IRD2B GTF2I	8.64e-07	4	210	3	22899722
Pubmed	Proteins implicated in muscular dystrophy and cancer are functional constituents of the centrosome.	DMD UTRN CAPN3	8.64e-07	4	210	3	35790299
Pubmed	TFII-I gene family during tooth development: candidate genes for tooth anomalies in Williams syndrome.	GTF2IRD2 GTF2IRD2B GTF2I	8.64e-07	4	210	3	17823943
Pubmed	Haploinsufficiency of Gtf2i, a gene deleted in Williams Syndrome, leads to increases in social interactions.	GTF2IRD2 GTF2IRD2B GTF2I	8.64e-07	4	210	3	21328569
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTAN1 SPTBN1 SPTBN5 SPTBN4	8.85e-07	13	210	4	18796539
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH8 DYNC1H1 DNAH10 DNAH17	1.23e-06	14	210	4	9373155
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	USP11 SPTAN1 SPTBN1 HSPH1 PSMD8 CLASP2 PRPF6 SPCS3 NCAPG MDN1 TELO2 SYNE2 SLMAP ALAS1 PLS3 MRPL21 SYNE1 POLE HEATR1 TARS2 RAB3GAP1 MACF1 AKAP11 WDR41 CRYBG3 VPS13B	1.25e-06	1487	210	26	33957083
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	PDXDC1 HSPH1 SCYL1 PSMD8 PGM3 TOMM70 SPCS3 NCAPG SLC12A9 TELO2 GCN1 DYNC1H1 POLE BTAF1 HEATR1 TARS2 RAB3GAP1 MTOR PRKDC SYMPK	1.31e-06	942	210	20	31073040
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PDXDC1 USP11 HSPH1 PRPF6 PGM3 NCAPG TELO2 DYNC1H1 CUL1 COG2 TARS2 RAB3GAP1 GTF2I WDR41 SYMPK	1.85e-06	560	210	15	35241646
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAP1A SPTAN1 SPTBN1 HSPH1 CLASP2 TOMM70 EPS15L1 PRMT5 CASKIN1 TJP2 DMD DNM1 UTRN PLS3 DYNC1H1 FLNB CARMIL2 SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 SLC8A2 MACF1 UNC13A	2.06e-06	1431	210	25	37142655
Pubmed	The Ku70 autoantigen interacts with p40phox in B lymphocytes.	NCF2 NCF4 PRKDC	2.15e-06	5	210	3	9914162
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	BAIAP3 UNC13B UNC13A	2.15e-06	5	210	3	26575293
Pubmed	Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.	PDXDC1 VPS13C SPTAN1 SPTBN1 HSPH1 SCYL1 EPS15L1 SYNE2 SLMAP GCN1 FLNB ATG2B RAB3GAP1 WDR41 VPS13B	2.20e-06	568	210	15	37774976
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	DENND4A USP11 SPTBN1 CLASP2 TOMM70 SYNE2 SLMAP UTRN FLNB SYNE1 CAPN3 MYOM3 C1QTNF9 MACF1	2.31e-06	497	210	14	23414517
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	PDXDC1 GRIPAP1 DENND4A VPS13C WDR81 SYNE2 PLD1 COG2 ATG2B APBB2 FURIN AKAP11 WDR41 VPS13B	2.71e-06	504	210	14	34432599
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	SPTAN1 SPTBN1 PRPF6 NCAPG MDN1 CPSF2 GCN1 DYNC1H1 CUL1 POLE BTAF1 PKP3 MACF1 PRKDC SYMPK	2.96e-06	582	210	15	20467437
Pubmed	Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	CLASP2 TELO2 MRC2 ACOT11 OSBPL3 AKAP11 KIF1C	3.01e-06	102	210	7	9734811
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SPTAN1 SPTBN1 HSPH1 MAP3K20 CLASP2 PRPF6 SPCS3 TJP2 PLD1 CPSF2 GCN1 PLS3 DYNC1H1 UNC13B CUL1 GAS2L3 APOA1 NUBPL THOC2 IBTK GTF2I OSBPL3 AATF RAB21	3.24e-06	1371	210	24	36244648
Pubmed	Serum proteomic profiling reveals fragments of MYOM3 as potential biomarkers for monitoring the outcome of therapeutic interventions in muscular dystrophies.	DMD CAPN3 MYOM3	4.28e-06	6	210	3	26060189
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	PRPF6 MDN1 PRMT5 SYNE2 TJP2 CPSF2 GCN1 UTRN DYNC1H1 FLNB GAS2L3 SYNE1 BTAF1 HEATR1 THOC2 PKP3 MACF1 AATF PRKDC RAB21	4.60e-06	1024	210	20	24711643
Pubmed	Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.	ATRIP TELO2 MTOR PRKDC	4.66e-06	19	210	4	20801936
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	PRPF6 NCAPG MDN1 GCN1 CUL1 HEATR1 THOC2 OXCT1 PKP3 SYMPK	4.90e-06	262	210	10	36880596
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	SPTAN1 SPTBN1 HSPH1 PRPF6 NCAPG MDN1 TONSL CPSF2 UTRN GTF2I AATF PRKDC	5.64e-06	394	210	12	27248496
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GRIPAP1 DENND4A GALC CENPB SCYL1 PSMD8 CLASP2 PRPF6 BBS9 PGM3 EPS15L1 EML5 GCN1 PLS3 DYNC1H1 ATG2B HEATR1 GTF2I MTOR OSBPL3 FUCA1 RAB21 KIF1C	5.75e-06	1321	210	23	27173435
Pubmed	Brain spectrin binding to the NMDA receptor is regulated by phosphorylation, calcium and calmodulin.	SPTAN1 GRIN2A GRIN2B	7.46e-06	7	210	3	9670010
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	COQ2 TENM2 TBC1D9 AFAP1L2 NLRC5 EPS8L3 UTRN DUSP6 HEATR1 CCDC57 PLA2R1 ITPRIP AKAP11 UNC80	7.64e-06	552	210	14	10737800
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	PDXDC1 SPTAN1 SPTBN1 PRPF6 TOMM70 TJP2 CPSF2 GCN1 UTRN DYNC1H1 FLNB HEATR1 PKP3 MACF1 PRKDC RAB21	7.66e-06	711	210	16	33022573
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RIPOR2 FSTL5 TENM2 TOMM70 BAIAP3 DYNC1H1 UNC13B SYNE1 CNKSR2 ACOT11 MACF1 VPS13B	7.83e-06	407	210	12	12693553
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	USP11 SPTAN1 SPTBN1 HSPH1 MAP3K20 PRPF6 CDCA2 NCAPG MDN1 GCN1 UTRN DYNC1H1 CUL1 FLNB POLE HEATR1 PAPSS2 RAB3GAP1 GTF2I OXCT1 MACF1 AATF PRKDC	8.47e-06	1353	210	23	29467282
Pubmed	Defining the membrane proteome of NK cells.	SCYL1 IRF4 CLASP2 PRPF6 TOMM70 EPS15L1 NCAPG MDN1 KIF15 PLD1 CPSF2 GCN1 DYNC1H1 CARMIL2 HEATR1 GTF2I MTOR OSBPL3 FURIN ITPRIP PRKDC	9.29e-06	1168	210	21	19946888
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	PDXDC1 SPTAN1 SPTBN1 HSPH1 RGPD1 PSMD8 ITGB4 NCAPG MDN1 DYNC1H1 FLNB TARS2 MTOR PRKDC KLHDC10	1.05e-05	647	210	15	26618866
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	BAIAP3 UNC13B UNC13A	1.19e-05	8	210	3	25609709
Pubmed	A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability.	TELO2 MTOR PRKDC	1.19e-05	8	210	3	20810650
Pubmed	Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.	MAP1A GRIN2A GRIN2B	1.19e-05	8	210	3	26609151
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	MAP1A SPTAN1 SPTBN1 SCYL1 IRF3 NCF2 CA14 PSMD8 PRPF6 BMX MDN1 PLS3 UNC13B GNPTAB CNKSR2 TARS2 NUBPL STK16 PLA2R1 MTOR FURIN WDR41	1.33e-05	1293	210	22	15342556
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MDN1 DMD FLNB SYNE1 THOC2 GTF2I MACF1 KIF13A VPS13B	1.38e-05	234	210	9	36243803
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTAN1 SPTBN1 SPTBN5 SPTBN4	1.48e-05	25	210	4	8493579
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	USP11 PSMD8 CLASP2 NCAPG CPSF2 DYNC1H1 UNC13B FLNB CARMIL2 SOX30 ZNF251 RAB3GAP1 MTOR FUCA1 FAHD1	1.57e-05	670	210	15	22990118
Pubmed	Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.	PDXDC1 GRIPAP1 PGM3 TELO2 EML3 MTOR PKP3 AKAP11	1.67e-05	183	210	8	31932471
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	GRIPAP1 SPTAN1 SPTBN1 HSPH1 PSMD8 PRPF6 NCAPG MDN1 UTRN PLS3 DYNC1H1 CUL1 FLNB THOC2 GTF2I MACF1 PRKDC	1.74e-05	847	210	17	35235311
Pubmed	Genome-wide association study of smoking initiation and current smoking.	SLC9A9 GRIN2A GRIN2B	1.77e-05	9	210	3	19268276
Pubmed	SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma.	TELO2 CUL1 MTOR	1.77e-05	9	210	3	23263282
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	CENPB USP11 IRF3 PSMD8 RXRA TOMM70 NCAPG MDN1 SLMAP CPSF2 DYNC1H1 CUL1 MRPL21 POLE BTAF1 HEATR1 SYMPK	2.01e-05	857	210	17	25609649
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	SPTAN1 SPTBN1 PSMD8 CLASP2 CDCA2 TOMM70 NCAPG KIF15 TELO2 SYNE2 DMD CPSF2 GCN1 UTRN DUSP6 TARS2 AATF CRYBG3 SYMPK	2.28e-05	1049	210	19	27880917
Pubmed	Evidence that the transcriptional repressor ICER is regulated via the N-end rule for ubiquitination.	USP11 GCN1 DYNC1H1 PRKDC	2.36e-05	28	210	4	35227662
Pubmed	Tel2 regulates the stability of PI3K-related protein kinases.	TELO2 MTOR PRKDC	2.52e-05	10	210	3	18160036
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	GRIPAP1 SPTAN1 SPTBN1 HSPH1 PSMD8 MDN1 DMD UTRN DYNC1H1 CUL1 FLNB MTOR MACF1	2.69e-05	538	210	13	28524877
Pubmed	USP7 controls NGN3 stability and pancreatic endocrine lineage development.	SPTAN1 SPTBN1 GCN1 GRIN2B MACF1	2.70e-05	58	210	5	37117185
Pubmed	The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.	SPTAN1 SPTBN1 HSPH1 CLASP2 NCAPG PRMT5 GCN1 FLNB PRKDC SYMPK	2.76e-05	320	210	10	28685749
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MAP1A PRPF6 PGM3 SPCS3 NCAPG GCN1 DNAH8 DYNC1H1 POLE HEATR1 RAB3GAP1 OXCT1 MTOR PRKDC RAB21	2.79e-05	704	210	15	29955894
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MAP1A SPTAN1 SPTBN1 HSPH1 TOMM70 EPS15L1 DNM1 DYNC1H1 GRIN2A GRIN2B BLZF1 TRIM23 MTOR ACOT11	2.82e-05	621	210	14	22794259
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	SPTAN1 HSPH1 PRMT5 SYNE2 DMD UTRN SYNE1 MACF1	2.84e-05	197	210	8	20811636
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	SPTAN1 SPTBN1 PLPPR3 TENM2 GRIN2A GRIN2B TRNT1 MACF1	2.84e-05	197	210	8	36604605
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	RIPOR2 HSPH1 PSMD8 ITGB4 SYNE2 DMD DNM1 DYNC1H1 MACF1 PRKDC	2.91e-05	322	210	10	26514267
Pubmed	UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target.	GCN1 TARS2 MTOR PRKDC	3.13e-05	30	210	4	32867711
Pubmed	Biological, clinical and population relevance of 95 loci for blood lipids.	LIPG OSBPL7 APOA5 CAPN3 APOA1 RAB3GAP1 MACF1	3.16e-05	146	210	7	20686565
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SPTAN1 EPS15L1 NCAPG TJP2 GCN1 PLS3 DYNC1H1 ATG2B HEATR1 THOC2 GTF2I PRKDC SYMPK	3.31e-05	549	210	13	38280479
Pubmed	OTUD4-mediated GSDME deubiquitination enhances radiosensitivity in nasopharyngeal carcinoma by inducing pyroptosis.	SPTAN1 SPTBN1 PRMT5	3.46e-05	11	210	3	36411454
Pubmed	Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.	TELO2 MTOR PRKDC	3.46e-05	11	210	3	20427287
Pubmed	Brain proteins interacting with the tetramerization region of non-erythroid alpha spectrin.	SPTAN1 SPTBN1 SPTBN4	3.46e-05	11	210	3	17607528
Pubmed	Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.	DMD UTRN	3.63e-05	2	210	2	10525423
Pubmed	In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.	DMD UTRN	3.63e-05	2	210	2	28790199
Pubmed	Structure and interfacial properties of human apolipoprotein A-V.	APOA5 APOA1	3.63e-05	2	210	2	12810715
Interaction	EEF1AKMT3 interactions	PDXDC1 GRIPAP1 VPS13C WDR81 NCAPG MDN1 TELO2 TONSL GCN1 ANKS1A POLE GTF2I OSBPL3 VPS13B SYMPK	6.13e-06	364	208	15	int:EEF1AKMT3
Interaction	ITGB2 interactions	SPTAN1 SPTBN1 NCF4 MDN1 FCER2 GCN1 DYNC1H1 FLNB APOA1	9.48e-06	132	208	9	int:ITGB2
Interaction	SIRT7 interactions	USP11 SPTAN1 SPTBN1 PRPF6 MDN1 PRMT5 SYNE2 TJP2 GCN1 UTRN DYNC1H1 FLNB POLE HEATR1 THOC2 GTF2I MTOR MACF1 AATF ELK4 PRKDC SYMPK	9.64e-06	744	208	22	int:SIRT7
Interaction	DISC1 interactions	GRIPAP1 MAP1A SPTAN1 SPTBN1 PGM3 SPCS3 TJP2 DMD UTRN DYNC1H1 SYNE1 GNPTAB CCDC57 SPTBN4 MACF1 AP4B1	1.05e-05	429	208	16	int:DISC1
Interaction	C2CD6 interactions	MAP1A SCYL1 UNC13B CCDC57 TRIM23 KRT75 ACOT11	1.24e-05	75	208	7	int:C2CD6
Interaction	GAN interactions	SPTAN1 PGM3 SPTBN5 PRMT5 SYNE2 DMD DNAH8 DNAH10 SYNE1 RTTN APBB2 KRT75	1.33e-05	253	208	12	int:GAN
Interaction	ATOH1 interactions	MAP1A USP11 MDN1 UTRN DYNC1H1 MACF1 PRKDC	1.89e-05	80	208	7	int:ATOH1
Interaction	FPR1 interactions	PDXDC1 PGM3 TELO2 GCN1 COG2 BTAF1 MTOR ITPRIP PRKDC	2.25e-05	147	208	9	int:FPR1
Interaction	NFKBIB interactions	PDXDC1 RXRA TONSL ANKS1A CUL1 GTF2I SYMPK	3.04e-05	86	208	7	int:NFKBIB
Interaction	STXBP1 interactions	SPTBN1 HSPH1 TBC1D9 CASKIN1 PLD1 DNM1 GRIN2B OXCT1 MACF1 UNC13A	3.06e-05	191	208	10	int:STXBP1
Interaction	FOXL1 interactions	CENPB TOMM70 NCAPG MDN1 CPSF2 DYNC1H1 POLE BTAF1 HEATR1 SYMPK	3.82e-05	196	208	10	int:FOXL1
Interaction	GPR17 interactions	PDXDC1 PGM3 NCAPG MDN1 ATRIP SLC12A9 TONSL COG2 BTAF1 HEATR1 MTOR PRKDC	4.02e-05	283	208	12	int:GPR17
Interaction	TNIK interactions	SPTAN1 SPTBN1 PSMD8 SPCS3 SYNE2 SLMAP DNM1 DYNC1H1 SYNE1 CNKSR2 GRIN2A GRIN2B MACF1 UNC13A	4.45e-05	381	208	14	int:TNIK
Interaction	NPY2R interactions	TELO2 GCN1 COG2 BTAF1 MTOR PRKDC	6.10e-05	66	208	6	int:NPY2R
Interaction	KALRN interactions	SPTAN1 SPTBN1 CNKSR2 GRIN2B MACF1 AKAP11 KIF1C	6.18e-05	96	208	7	int:KALRN
Interaction	AGAP2 interactions	MAP1A SPTAN1 SPTBN1 DNM1 DYNC1H1 SYNE1 CNKSR2 GRIN2A GRIN2B MACF1	6.82e-05	210	208	10	int:AGAP2
Interaction	ITGB3 interactions	SPTAN1 SPTBN1 HSPH1 NCAPG MDN1 GCN1 DYNC1H1 FLNB PRKDC	7.03e-05	170	208	9	int:ITGB3
Interaction	GPR45 interactions	PDXDC1 PGM3 MDN1 TELO2 TONSL GCN1 COG2 BTAF1 HEATR1 TARS2 NUBPL MTOR	7.05e-05	300	208	12	int:GPR45
GeneFamily	EF-hand domain containing\|Spectrins	SPTAN1 SPTBN1 SPTBN5 SPTBN4	1.25e-07	7	142	4	1113
GeneFamily	EF-hand domain containing	FSTL5 SPTAN1 FSTL4 TBC1D9 EPS15L1 PLS3 GNPTAB CAPN3 CAPNS2 MACF1 KCNIP4	1.27e-06	219	142	11	863
GeneFamily	Dyneins, axonemal	DNAH14 DNAH8 DNAH10 DNAH17	8.02e-06	17	142	4	536
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN1 BMX AFAP1L2 OSBPL7 PLD1 DNM1 CNKSR2 SPTBN4 OSBPL3	3.67e-05	206	142	9	682
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE2 SYNE1	3.64e-04	4	142	2	1252
GeneFamily	UNC13 homologs	UNC13B UNC13A	3.64e-04	4	142	2	836
GeneFamily	C-type lectin domain family	FCER2 MRC2 KLRB1 PLA2R1	5.01e-04	47	142	4	494
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN2A GRIN2B	1.25e-03	7	142	2	1201
Coexpression	KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3	DENND4A VPS13C SPTBN1 WDR81 COQ2 AFAP1L2 SYNE2 OSBPL7 GTF2IRD2 TJP2 PLD1 SDR16C5 PLS3 DUSP6 RTTN BLZF1 GTF2I OSBPL3 FURIN ITPRIP AP4B1	4.34e-06	843	209	21	M2356
Coexpression	BILBAN_B_CLL_LPL_UP	WSB2 IRF4 FCER2 DMD FLNB HEATR1	1.22e-05	64	209	6	M19930
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SPTAN1 TENM2 DNM1 SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 KCNIP4 UNC13A UNC80	2.99e-09	198	211	11	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Control-Myeloid-DC1\|Control / Condition, Lineage and Cell class	SLC9A9 MRC2 DMD CCDC102A FLNB CAPN3 LRRK1 OXCT1 PIK3R6	2.16e-07	181	211	9	5a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SPTAN1 SPTBN1 SYNE2 UTRN KLRB1 HEATR1 LRRK1 FURIN MACF1	3.26e-07	190	211	9	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TENM2 DNM1 CARMIL2 GRIN2A GRIN2B SPTBN4 KCNIP4 UNC13A UNC80	3.26e-07	190	211	9	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	FSTL4 TENM2 DNM1 GRIN2A GRIN2B SPTBN4 KCNIP4 UNC13A UNC80	3.56e-07	192	211	9	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM2 DNM1 CNKSR2 GRIN2A GRIN2B RTL1 KCNIP4 UNC13A UNC80	4.06e-07	195	211	9	ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDXDC1 CENPB SPTAN1 SPTBN1 UTRN PLS3 DYNC1H1 IBTK MACF1	4.24e-07	196	211	9	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDXDC1 CENPB SPTAN1 SPTBN1 UTRN PLS3 DYNC1H1 IBTK MACF1	4.24e-07	196	211	9	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	Control-Control-Lymphocyte-T/NK-CD4+_T_activated\|Control / Disease, condition lineage and cell class	SPTBN1 CDCA2 MRC2 SYNE2 NLRC5 TEX14 PLA2R1 MACF1 AKAP11	4.61e-07	198	211	9	ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE2 NLRC5 UTRN SYNE1 GNPTAB RTTN BTAF1 MACF1 VPS13B	4.81e-07	199	211	9	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3C BMX AFAP1L2 LIPG COL27A1 CAPN3 GRIN2B FURIN	8.20e-07	156	211	8	58b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDZRN4 DNAH10 ATP13A5 GRIN2B FSHR CNTN3 MYH15 UNC80	9.93e-07	160	211	8	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDZRN4 DNAH10 ATP13A5 GRIN2B FSHR CNTN3 MYH15 UNC80	9.93e-07	160	211	8	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SLC9A9 FCER2 CNKSR2 GXYLT2 MALRD1 CNTN3 VPS13B UNC80	1.31e-06	166	211	8	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DENND4A HSPH1 SYNE2 NLRC5 UTRN SYNE1 BTAF1 MACF1	1.64e-06	171	211	8	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	IIH-CD8-naive_CD4\|IIH / Condition, Cell_class and T cell subcluster	WDR81 IRF4 ANKMY1 OSBPL7 ALAS1 POLE ZNF830 AP4B1	1.78e-06	173	211	8	4f2843371d18af766c1892529ce286f56c956fde
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 FSTL4 TENM2 TDO2 PAPSS2 MALRD1 FSHR EPHA3	2.03e-06	176	211	8	cd4b9211652596c42e7af318bcd464681daebb10
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 FSTL4 PDZRN4 TDO2 PAPSS2 MALRD1 FSHR EPHA3	2.40e-06	180	211	8	2ae39e26a8e7d5d4d3e1e71609a8ec36fd9855aa
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 FSTL4 PDZRN4 TDO2 LRRK1 PAPSS2 FSHR EPHA3	2.50e-06	181	211	8	6e8c5460021d3999daec58e3d6661a6fa998fd16
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RIPOR2 SPTAN1 SPTBN1 TOMM70 SYNE2 GCN1 CARMIL2 ATP8B2	2.60e-06	182	211	8	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RIPOR2 SPTAN1 SPTBN1 TOMM70 SYNE2 GCN1 CARMIL2 ATP8B2	2.60e-06	182	211	8	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 SPTAN1 SPTBN1 TOMM70 SYNE2 GCN1 CARMIL2 ATP8B2	2.60e-06	182	211	8	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 SPTAN1 SPTBN1 TOMM70 SYNE2 GCN1 CARMIL2 ATP8B2	2.60e-06	182	211	8	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	SLMAP DMD PLS3 PDZRN4 FLNB TNFRSF11B MYH15 KIF13A	2.71e-06	183	211	8	818fd886e0188091310825f9145fa53328f2c979
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	RIPOR2 SPTAN1 SPTBN1 TOMM70 SYNE2 GCN1 CARMIL2 ATP8B2	2.71e-06	183	211	8	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 FSTL4 TDO2 LRRK1 PAPSS2 MALRD1 FSHR EPHA3	2.71e-06	183	211	8	274076a0978bce2bd53a1732045f18ef0f2d9985
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 UTRN UNC13B FLNB APBB2 C1QTNF9	3.06e-06	186	211	8	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TENM2 TBC1D9 DNM1 GRIN2B SPTBN4 KCNIP4 UNC13A UNC80	3.06e-06	186	211	8	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CLASP2 DMD PLS3 PDZRN4 FLNB TNFRSF11B MACF1 KIF13A	3.31e-06	188	211	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DENND4A VPS13C HSPH1 SYNE2 UTRN DYNC1H1 BTAF1 MACF1	3.31e-06	188	211	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM2 EML5 FCER2 BAIAP3 PAPSS2 SPTBN4 ACOT11 UNC80	3.31e-06	188	211	8	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	SLC9A9 SMPDL3A PLAC9 COL13A1 CNKSR2 PLA2R1 CNTN3 MACF1	4.02e-06	193	211	8	9f69edc97b868d23998abc98928a2e89a885ef8a
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH7 TENM2 DNM1 GRIN2A GRIN2B RTL1 KCNIP4 UNC80	4.02e-06	193	211	8	461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH7 FSTL4 DNM1 GRIN2B SPTBN4 SLC8A2 UNC13A UNC80	4.02e-06	193	211	8	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH7 FSTL4 DNM1 GRIN2B SPTBN4 SLC8A2 UNC13A UNC80	4.02e-06	193	211	8	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH7 TENM2 DNM1 GRIN2A GRIN2B RTL1 KCNIP4 UNC80	4.02e-06	193	211	8	0dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH7 FSTL4 DNM1 GRIN2B SPTBN4 SLC8A2 UNC13A UNC80	4.02e-06	193	211	8	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HSPH1 FSTL4 TENM2 UNC13B CNKSR2 GRIN2A KCNIP4 UNC13A	4.34e-06	195	211	8	2e1df01bf6e4e98e6cd9fb50926e34c5077b8666
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	HSPH1 FSTL4 TENM2 COL13A1 CNKSR2 GRIN2A PAPSS2 KCNIP4	4.34e-06	195	211	8	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM2 DNM1 SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 UNC80	4.51e-06	196	211	8	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Striatum-Neuronal-Excitatory\|Striatum / BrainAtlas - Mouse McCarroll V32	GRIPAP1 WSB2 TOMM70 CNKSR2 GRIN2A GRIN2B SPTBN4 SLC8A2	4.51e-06	196	211	8	67400193ba469cf4d939e94f5ed94995e384bc07
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNH7 FSTL5 TENM2 BAIAP3 KCNIP4 UNC13A UNC80 EPHA3	4.85e-06	198	211	8	8f25e8dff42bad8e779ca618bdb1cb1610667962
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	FSTL5 ANKMY1 EML5 MRC2 COL27A1 CNKSR2 TDO2 MACF1	4.85e-06	198	211	8	0c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_neuro-secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KCNH7 FSTL5 TENM2 BAIAP3 KCNIP4 UNC13A UNC80 EPHA3	4.85e-06	198	211	8	e3e0aa3ef20b2370f5b133048510677aaa562dfa
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM2 DNM1 SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 UNC80	4.85e-06	198	211	8	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM2 DNM1 SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 UNC80	4.85e-06	198	211	8	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	SPTAN1 SPTBN1 MAP4K2 UNC13B APBB2 PAPSS2 GTF2I MACF1	5.04e-06	199	211	8	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SPTAN1 SPTBN1 SYNE2 NLRC5 KLRB1 SYNE1 ATP8B2 MACF1	5.04e-06	199	211	8	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ITGB4 TENM2 AFAP1L2 MRC2 CASKIN1 PLAC9 PDZRN4 CNKSR2	5.04e-06	199	211	8	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VPS13C NOXA1 EML5 SLC12A9 SYNE2 UTRN OSBPL3 PKP3	5.04e-06	199	211	8	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T\|COVID-19_Mild / Disease, condition lineage and cell class	SPTAN1 SPTBN1 IRF4 AFAP1L2 SYNE2 FLNB BLZF1 MACF1	5.04e-06	199	211	8	f307d4887b28cf60a591439e278fd668409cb104
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC9A9 SPTBN1 MRC2 COL13A1 SYNE1 TDO2 PAPSS2 MACF1	5.23e-06	200	211	8	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Neuronal\|World / cells hierarchy compared to all cells using T-Statistic	TENM2 DNM1 SYNE1 CNKSR2 GRIN2A GRIN2B SPTBN4 UNC80	5.23e-06	200	211	8	48d801219bc771d6c7e151dc88ca4c179988de85
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	VPS13C NOXA1 EML5 SYNE2 ALAS1 UTRN OSBPL3 PKP3	5.23e-06	200	211	8	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DENND4A DHDDS NCF2 NCF4 CDCA2 NCAPG KIF15	6.31e-06	146	211	7	45d7cb73776e60d22f335a651845e21e16948fcc
ToppCell	COVID-19-kidney-Technical/muscle_(Mes)\|kidney / Disease (COVID-19 only), tissue and cell type	KCNH7 FSTL5 TENM2 DMD DNAH8 PDZRN4 EPHA3	1.10e-05	159	211	7	5335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-AT1_Progenitor\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FSTL5 TINAG SLC12A9 C1QTNF2 GCN1 CCDC102A POLE	1.20e-05	161	211	7	357c060e4d2ea1257c73b346dcd4a27dbc5db813
ToppCell	5'-Adult-Appendix-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3C BMX AFAP1L2 LIPG COL27A1 GRIN2B TNFRSF11B	1.24e-05	162	211	7	ded08da888d8c481f0f96d1e0bfd03d617966910
ToppCell	facs-Thymus-Epithelium-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMUG1 GAS2 WSB2 EPS15L1 CARMIL2 PAPSS2	1.41e-05	110	211	6	3a641dced828ed97a8eea70d0a7b76f33630c9be
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA14 C1QTNF2 CARMIL2 TDO2 BLZF1 CCDC57 MUC6	1.70e-05	170	211	7	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CA14 C1QTNF2 CARMIL2 TDO2 BLZF1 CCDC57 MUC6	1.70e-05	170	211	7	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SPTBN5 SYNE2 OSBPL7 KLRB1 COL13A1 SYNE1 ITPRIP	1.77e-05	171	211	7	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC5 HSPH1 SCYL1 SPCS3 FCER2 DNAH8 PDZRN4	1.90e-05	173	211	7	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERCC5 HSPH1 SCYL1 SPCS3 FCER2 DNAH8 PDZRN4	1.90e-05	173	211	7	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SOX30 ATP13A5 TEX14 PLA2R1 PKP3	1.91e-05	69	211	5	cdd42abdd072aa438830d837ee857529269a81e0
ToppCell	Substantia_nigra-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3-MURAL_Mural.Rgs5Acta2.Rgs5_(Mural.Rgs5Acta2.Rgs5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SOX30 ATP13A5 TEX14 PLA2R1 PKP3	1.91e-05	69	211	5	a157b1582401cebd222343d94086dbea876140c2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	C1QTNF2 DMD DNAH8 UTRN PDZRN4 COL13A1 UNC13A	2.05e-05	175	211	7	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231\|Adult / Lineage, Cell type, age group and donor	KCNH7 GAS2 FSTL4 KCNIP4 UNC13A UNC80 EPHA3	2.05e-05	175	211	7	8d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCell	Adult-Epithelial-lung_neuroendocrine_cell_(PNEC)\|Adult / Lineage, Cell type, age group and donor	KCNH7 GAS2 FSTL4 KCNIP4 UNC13A UNC80 EPHA3	2.05e-05	175	211	7	4db1a3c284488b3f6de7568363f176d74e2a4587
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	C1QTNF2 DMD DNAH8 UTRN PDZRN4 COL13A1 UNC13A	2.05e-05	175	211	7	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FCER2 PDZRN4 PNLIP ATP13A5 GRIN2B MYH15 UNC80	2.05e-05	175	211	7	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C PRPF6 SLMAP DMD IBTK MACF1 ELK4	2.13e-05	176	211	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 LIPG MRC2 UTRN SYNE1 TDO2 DNAH17	2.13e-05	176	211	7	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EML5 CASKIN1 BAIAP3 DNAH10 CNKSR2 RTL1 UNC13A	2.21e-05	177	211	7	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	(3)_Chondrocytes-(32)_Chondro-prehyper-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	TENM2 FCER2 DNAH10 COL27A1 PAPSS2 TNFRSF11B GXYLT2	2.29e-05	178	211	7	c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FSTL5 FSTL4 TDO2 PAPSS2 MALRD1 FSHR EPHA3	2.29e-05	178	211	7	5522b179c2e7dd707de01e2df10556349d0382a6
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3C BMX AFAP1L2 COL27A1 GRIN2B ARSD FURIN	2.37e-05	179	211	7	906555ce2ca264a0215b120c7ff7c9b411de6a34
ToppCell	390C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SLC9A9 COQ2 TONSL CARMIL2 HEATR1 NUBPL GTF2IRD2B	2.37e-05	179	211	7	3edcd1356e49b1f5514c585861999e079ca5e579
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A9 CDCA2 NCAPG KIF15 DNM1 GAS2L3 POLE	2.64e-05	182	211	7	0fc45214f0b0766f69be6eff69cc4bec574023aa
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A9 CDCA2 NCAPG KIF15 DNAH8 GAS2L3 POLE	2.64e-05	182	211	7	bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FSTL4 AFAP1L2 PLS3 GRIN2B PAPSS2 CCDC42 KCNIP4	2.64e-05	182	211	7	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 PLAC9 UTRN FLNB C1QTNF9	2.64e-05	182	211	7	c7f2d24697affa530b748ab32b1d40bdc1bdc20a
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 PLAC9 UTRN FLNB C1QTNF9	2.64e-05	182	211	7	d95635b74e8cd8bc00bfe40340806b59fb9bee43
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS22 DMD DNAH10 CNKSR2 GRIN2B MYH15 UNC80	2.83e-05	184	211	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Control-Myeloid-DC1\|Myeloid / Condition, Lineage and Cell class	SLC9A9 MRC2 DMD CCDC102A FLNB OXCT1 PIK3R6	2.83e-05	184	211	7	b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS22 DMD DNAH10 CNKSR2 GRIN2B MYH15 UNC80	2.83e-05	184	211	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS22 DMD DNAH10 CNKSR2 GRIN2B MYH15 UNC80	2.83e-05	184	211	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	COVID-19_Severe-gd_T\|COVID-19_Severe / Disease condition and Cell class	RIPOR2 SYNE2 KLRB1 DNAH10 SYNE1 GNPTAB MACF1	2.83e-05	184	211	7	791f1bcb954aadc63d4117c400537d036f68734d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MRC2 C1QTNF2 PLAC9 DNM1 COL27A1 TDO2 EPHA3	2.93e-05	185	211	7	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	VPS13C RGS22 RXRA DNAH8 DUSP6 GRIN2B MYH15	3.03e-05	186	211	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 UTRN UNC13B FLNB APBB2	3.13e-05	187	211	7	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	TCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	TENM2 SDR16C5 MYOM3 CAPNS2 KRT75 PKP3 CYP4F22	3.13e-05	187	211	7	2ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 UTRN UNC13B FLNB APBB2	3.13e-05	187	211	7	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB4 BMX AFAP1L2 UTRN UNC13B FLNB APBB2	3.24e-05	188	211	7	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	DMD PLS3 PDZRN4 FLNB TNFRSF11B MACF1 KIF13A	3.35e-05	189	211	7	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KCNH7 FSTL5 BAIAP3 FLNB SPTBN4 UNC13A UNC80	3.47e-05	190	211	7	b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM2 COL13A1 CNKSR2 GRIN2A PAPSS2 FSHR KCNIP4	3.47e-05	190	211	7	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 UTRN UNC13B FLNB C1QTNF9	3.59e-05	191	211	7	6e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGB4 TENM2 FCGBP SYNE2 PDZRN4 CAPNS2 PKP3	3.59e-05	191	211	7	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGB4 BMX AFAP1L2 UTRN UNC13B FLNB C1QTNF9	3.59e-05	191	211	7	482db995930346be69072ace2fd78fd453e97fb5
Computational	Actin cytoskeleton binding.	SPTAN1 SPTBN1 PLS3 FLNB MACF1	2.05e-05	30	123	5	MODULE_524
Computational	Genes in the cancer module 419.	SPTAN1 SPTBN1 PLS3 FLNB MACF1	3.86e-05	34	123	5	MODULE_419
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SYNE2 UTRN DYNC1H1 SYNE1 MACF1	2.31e-04	49	123	5	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Drug	plakin	SPTAN1 SPTBN1 GAS2 DHDDS ITGB4 SPTBN5 SYNE2 DMD UTRN PLS3 DYNC1H1 SYNE1 SPTBN4 KRT75 MACF1	9.68e-16	82	209	15	CID000018752
Drug	dimyristoylphosphatidylcholine	SPTAN1 SPTBN1 SPTBN5 APOA5 APOA1 SPTBN4 MTOR	1.98e-06	64	209	7	CID000026197
Drug	Thalidomide [50-35-1]; Up 200; 15.4uM; PC3; HT_HG-U133A	PXMP4 MAP1A ANKMY1 TELO2 BAIAP3 COL13A1 CCDC57 ATP8B2 ARSD PKP3 KIF1C	2.44e-06	199	209	11	2095_UP
Drug	ADPribulose	SPTAN1 SPTBN1 SPTBN5 SPTBN4	4.62e-06	13	209	4	CID000197570
Drug	PRODAN	SPTAN1 SPTBN1 SPTBN5 SPTBN4	8.70e-06	15	209	4	CID000028127
Drug	Methocarbamol [532-03-6]; Down 200; 16.6uM; PC3; HT_HG-U133A	SPTAN1 UTRN MAP4K2 APBB2 EML3 TNFRSF11B STK16 IBTK FURIN KIF1C	1.30e-05	194	209	10	2111_DN
Drug	Hecogenin [467-55-0]; Down 200; 9.2uM; MCF7; HT_HG-U133A	SPTBN1 ABCC10 ATP8B2 EML3 RAB3GAP1 MTOR PKP3 ELK4 KLHDC10 KIF1C	1.36e-05	195	209	10	3457_DN
Drug	rosiglitazone; Up 200; 10uM; MCF7; HT_HG-U133A	SPTAN1 IRF4 EPS8L3 PLD1 APBB2 EML3 ACOT11 KIF13A MUC6 EPHA3	1.42e-05	196	209	10	5230_UP
Drug	Guaifenesin [93-14-1]; Up 200; 20.2uM; HL60; HT_HG-U133A	ANKMY1 RXRA SPTBN5 BAIAP3 APBB2 GRIN2B CCDC57 ELK4 STAG3 UNC13A	1.42e-05	196	209	10	2569_UP
Drug	Altretamine [654-05-6]; Down 200; 19uM; HL60; HT_HG-U133A	BBS9 EPS15L1 SLC12A9 MAP4K2 UNC13B PAPSS2 ATP8B2 TNFRSF11B FURIN SYMPK	1.49e-05	197	209	10	3090_DN
Drug	Hexetidine [141-94-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MAP3K20 BBS9 ITGB4 TELO2 UTRN COL13A1 APBB2 BLZF1 EML3 KIF13A	1.55e-05	198	209	10	5420_DN
Drug	Gabazine [105538-73-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A	MAP1A IRF4 ANKMY1 MRC2 PLD1 BAIAP3 MAP4K2 COL13A1 SOX30 CCDC57	1.69e-05	200	209	10	4820_UP
Drug	R4--a	DMD UTRN GRIN2A GRIN2B	2.98e-05	20	209	4	CID005289251
Disease	Duchenne muscular dystrophy (implicated_via_orthology)	DMD UTRN CAPN3 EML3	1.10e-04	36	204	4	DOID:11723 (implicated_via_orthology)
Disease	unipolar depression, bipolar disorder	FSTL5 TENM2 SPCS3 SYNE2 SYNE1 OSBPL3 MYH15	1.11e-04	156	204	7	EFO_0003761, MONDO_0004985
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	1.42e-04	3	204	2	DOID:0111590 (implicated_via_orthology)
Disease	Infantile Obesity	APOA5 APOA1	2.83e-04	4	204	2	C4553478
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN1 SPTBN4	2.83e-04	4	204	2	DOID:0050882 (implicated_via_orthology)
Disease	Childhood Overweight	APOA5 APOA1	2.83e-04	4	204	2	C4521075
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE2 SYNE1	2.83e-04	4	204	2	cv:CN293514
Disease	Pediatric Obesity	APOA5 APOA1	2.83e-04	4	204	2	C2362324
Disease	Adolescent Overweight	APOA5 APOA1	2.83e-04	4	204	2	C4704956
Disease	Infant Overweight	APOA5 APOA1	2.83e-04	4	204	2	C4704955
Disease	Adolescent Obesity	APOA5 APOA1	2.83e-04	4	204	2	C4317171
Disease	urate measurement, bone density	FSTL5 CLASP2 TENM2 DNAH14 CPSF2 DNAH8 UTRN SYNE1 TDO2 GXYLT2 C1QTNF9 PRKDC GABRA6	4.03e-04	619	204	13	EFO_0003923, EFO_0004531
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE2 SYNE1	4.69e-04	5	204	2	C1450051
Disease	Chronic granulomatous disease	NCF2 NCF4	4.69e-04	5	204	2	cv:C0018203
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE2 SYNE1	4.69e-04	5	204	2	C0410190
Disease	diacylglycerol 44:6 measurement	SYNE2 APOA5	4.69e-04	5	204	2	EFO_0020070
Disease	low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	PDXDC1 LIPG SYNE2 DNAH10 APOA5 CAPN3 MACF1	5.06e-04	200	204	7	EFO_0004611, EFO_0020945
Disease	QRS duration, response to sulfonylurea	COQ2 TINAG MDN1	5.21e-04	23	204	3	EFO_0005055, EFO_0007922
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	PDXDC1 LIPG SYNE2 NLRC5 DNAH10 APOA5 CAPN3 MACF1	5.30e-04	264	204	8	EFO_0008317, EFO_0020944
Disease	triglycerides:total lipids ratio, high density lipoprotein cholesterol measurement	PDXDC1 SYNE2 NLRC5 MAP4K2 DNAH10 APOA5 CAPN3	6.03e-04	206	204	7	EFO_0004612, EFO_0020947
Disease	Emery-Dreifuss muscular dystrophy	SYNE2 SYNE1	7.01e-04	6	204	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE2 SYNE1	7.01e-04	6	204	2	C0410189
Disease	sexual dimorphism measurement	PXMP4 PDXDC1 RGPD1 GALP SPTBN5 LIPG CASKIN1 NLRC5 SDR16C5 GCN1 ANKS1A DNAH10 APOA5 APOA1 GRIN2A ZNF557 MACF1 SMIM44	7.14e-04	1106	204	18	EFO_0021796
Disease	phosphatidylcholine measurement	PDXDC1 LIPG SYNE2 DYNC1H1 APOA5 APOA1 MALRD1 MACF1	8.52e-04	284	204	8	EFO_0010226
Disease	apolipoprotein A 1 measurement, apolipoprotein B measurement	LIPG NLRC5 ALAS1 DNAH10 APOA5	9.03e-04	107	204	5	EFO_0004614, EFO_0004615
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	PDXDC1 LIPG SYNE2 NLRC5 APOA5 CAPN3 MACF1	9.35e-04	222	204	7	EFO_0008317, EFO_0020943
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE2 SYNE1	9.76e-04	7	204	2	C0751337
Disease	epilepsy (implicated_via_orthology)	KCNH7 DYNC1H1 UNC13B GRIN2A GRIN2B UNC13A	9.80e-04	163	204	6	DOID:1826 (implicated_via_orthology)
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	PDXDC1 SYNE2 MAP4K2 DNAH10 APOA5 CAPN3 MACF1	9.85e-04	224	204	7	EFO_0004530, EFO_0008317
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	PDXDC1 LIPG SYNE2 NLRC5 DNAH10 APOA5 CAPN3 MACF1	9.97e-04	291	204	8	EFO_0008317, EFO_0020946
Disease	bipolar disorder (is_implicated_in)	SYNE1 GRIN2A GRIN2B	1.04e-03	29	204	3	DOID:3312 (is_implicated_in)
Disease	Epileptic encephalopathy	DNM1 GRIN2B MTOR	1.15e-03	30	204	3	C0543888
Disease	Colorectal Carcinoma	FSTL5 HTR3C NCAPG DMD DNAH8 PDZRN4 UNC13B SYNE1 POLE CNKSR2 GRIN2A EPHA3 GABRA6	1.28e-03	702	204	13	C0009402
Disease	placental insufficiency (biomarker_via_orthology)	GRIN2A GRIN2B	1.30e-03	8	204	2	DOID:3891 (biomarker_via_orthology)
Disease	cognitive disorder (biomarker_via_orthology)	GRIN2A GRIN2B	1.30e-03	8	204	2	DOID:1561 (biomarker_via_orthology)
Disease	acid sphingomyelinase-like phosphodiesterase 3a measurement	SMPDL3A GNPTAB	1.30e-03	8	204	2	EFO_0008013
Disease	susceptibility to mononucleosis measurement	MDN1 DMD DNAH8 CUL1	1.35e-03	69	204	4	EFO_0008403
Disease	Large cell carcinoma of lung	BMX MTOR EPHA3	1.39e-03	32	204	3	C0345958
Disease	age at first sexual intercourse measurement	PDXDC1 MAP3K20 IRF4 TENM2 UTRN PDZRN4 DUSP6 FURIN CNTN3	1.46e-03	383	204	9	EFO_0009749
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	PDXDC1 LIPG SYNE2 APOA5 MACF1	1.56e-03	121	204	5	EFO_0008595, EFO_0020943
Disease	cognitive disorder (is_implicated_in)	DMD APBB2	1.66e-03	9	204	2	DOID:1561 (is_implicated_in)
Disease	lifestyle measurement, systolic blood pressure	SLC9A9 CDCA2	1.66e-03	9	204	2	EFO_0006335, EFO_0010724
Disease	primary dental caries	FSTL4 GRIN2B OSBPL3	1.66e-03	34	204	3	EFO_0600095
Disease	heel bone mineral density, urate measurement	FSTL5 DNAH14 UTRN ATP13A5 OSBPL3 WDR41	1.72e-03	182	204	6	EFO_0004531, EFO_0009270
Disease	free cholesterol in small HDL measurement	LIPG NLRC5 APOA1	1.81e-03	35	204	3	EFO_0022270
Disease	Sarcomatoid Renal Cell Carcinoma	PDXDC1 SYNE2 SPTBN4 MTOR AP5M1	2.00e-03	128	204	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	PDXDC1 SYNE2 SPTBN4 MTOR AP5M1	2.00e-03	128	204	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	PDXDC1 SYNE2 SPTBN4 MTOR AP5M1	2.00e-03	128	204	5	C1266044
Disease	Papillary Renal Cell Carcinoma	PDXDC1 SYNE2 SPTBN4 MTOR AP5M1	2.00e-03	128	204	5	C1306837
Disease	Renal Cell Carcinoma	PDXDC1 SYNE2 SPTBN4 MTOR AP5M1	2.00e-03	128	204	5	C0007134
Disease	reaction time measurement	KCNH7 NCF2 COQ2 TENM2 RXRA SLMAP PDZRN4 DNAH10 GRIN2A GRIN2B NUBPL MYH15	2.21e-03	658	204	12	EFO_0008393
Disease	hyperhomocysteinemia (implicated_via_orthology)	GRIN2A GRIN2B	2.51e-03	11	204	2	DOID:9279 (implicated_via_orthology)
Disease	vascular dementia (is_marker_for)	GRIN2A GRIN2B	2.51e-03	11	204	2	DOID:8725 (is_marker_for)
Disease	quality of life during menstruation measurement, dysmenorrheic pain measurement	GRIN2A VPS13B	2.51e-03	11	204	2	EFO_0007889, EFO_0009366
Disease	Combined immunodeficiency	PGM3 CARMIL2 PRKDC	2.86e-03	41	204	3	C0494261
Disease	complex trait	SLC12A9 LIPG NLRC5 MAP4K2 APOA5 APOA1 MACF1	2.90e-03	271	204	7	EFO_0010578
Disease	thalamus volume	GALC RIPOR2 MACF1 EPHA3	2.90e-03	85	204	4	EFO_0006935
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE2 SYNE1	3.00e-03	12	204	2	DOID:11726 (implicated_via_orthology)
Disease	beta-endorphin measurement	APOA5 APOA1	3.00e-03	12	204	2	EFO_0008034
Disease	level of Phosphatidylinositol (16:0_18:1) in blood serum	PDXDC1 APOA5	3.00e-03	12	204	2	OBA_2045152
Disease	cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement	PDXDC1 LIPG NLRC5 DNAH10 APOA5 CAPN3 MACF1	3.20e-03	276	204	7	EFO_0004612, EFO_0020943
Disease	hereditary spastic paraplegia (implicated_via_orthology)	DNM1 CAPN3 ATP13A5	3.28e-03	43	204	3	DOID:2476 (implicated_via_orthology)
Disease	sphingomyelin measurement	PDXDC1 HTR3C LIPG SYNE2 DYNC1H1 APOA5 APOA1	3.33e-03	278	204	7	EFO_0010118
Disease	Malignant neoplasm of salivary gland	GAS2 ITGB4 STAG3L1	3.73e-03	45	204	3	C0220636
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	PDXDC1 SYNE2 SPTBN4 MTOR AP5M1	3.74e-03	148	204	5	C0279702
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	PDXDC1 SYNE2 APOA5 CAPN3 MACF1	3.96e-03	150	204	5	EFO_0004611, EFO_0020947
Disease	Malformations of Cortical Development	DYNC1H1 MTOR	4.10e-03	14	204	2	C1955869
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	PDXDC1 LIPG	4.10e-03	14	204	2	EFO_0022085
Disease	Cortical Dysplasia	DYNC1H1 MTOR	4.10e-03	14	204	2	C0431380
Disease	Salivary Gland Neoplasms	GAS2 ITGB4 STAG3L1	4.22e-03	47	204	3	C0036095
Disease	total cholesterol measurement, very low density lipoprotein cholesterol measurement	PDXDC1 MAP1A LIPG NLRC5 DNAH10 APOA5	4.80e-03	224	204	6	EFO_0004574, EFO_0008317
Disease	alkaline phosphatase measurement	RIPOR2 MAP1A SPTBN1 WDR81 DHDDS ATRIP SLC12A9 CASKIN1 TONSL UTRN MAP4K2 ABCC10 PDZRN4 TNFRSF11B MACF1	4.85e-03	1015	204	15	EFO_0004533
Disease	Adenoid Cystic Carcinoma	GAS2 ITGB4 STAG3L1 PRKDC	5.19e-03	100	204	4	C0010606
Disease	infantile hypertrophic pyloric stenosis	SLMAP APOA1	5.35e-03	16	204	2	EFO_0004707
Disease	idiopathic scoliosis (implicated_via_orthology)	PRMT5 DNAH10	5.35e-03	16	204	2	DOID:0060250 (implicated_via_orthology)
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	LIPG SYNE2 APOA5 MACF1	5.76e-03	103	204	4	EFO_0008595, EFO_0020944
Disease	HIV Infections	HSPH1 PSMD8 FCER2 APOA1	5.76e-03	103	204	4	C0019693
Disease	HIV Coinfection	HSPH1 PSMD8 FCER2 APOA1	5.76e-03	103	204	4	C4505456
Disease	non-alcoholic fatty liver disease, cirrhosis of liver	SLC9A9 COL13A1 SMIM44	5.92e-03	53	204	3	EFO_0001422, EFO_0003095
Disease	proprotein convertase subtilisin/kexin type 7 measurement	APOA5 APOA1	6.04e-03	17	204	2	EFO_0008270
Disease	muscular dystrophy (is_implicated_in)	SYNE1 CAPN3	6.04e-03	17	204	2	DOID:9884 (is_implicated_in)
Disease	respiratory symptom change measurement, response to placebo	BBS9 CDCA2	6.04e-03	17	204	2	EFO_0008344, EFO_0010068
Disease	triglyceride measurement, low density lipoprotein cholesterol measurement	SYNE2 MAP4K2 DNAH10 APOA5 CAPN3	6.06e-03	166	204	5	EFO_0004530, EFO_0004611
Disease	Metastatic melanoma	SCYL1 MTOR PRKDC	6.23e-03	54	204	3	C0278883
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement	PDXDC1 DNAH10 APOA5 CAPN3	6.37e-03	106	204	4	EFO_0008317, EFO_0008596
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	PDXDC1 LIPG NLRC5 APOA5 CAPN3 MACF1	6.53e-03	239	204	6	EFO_0008317, EFO_0020945
Disease	high density lipoprotein particle size measurement	PDXDC1 LIPG NLRC5 DNAH10 APOA5	6.69e-03	170	204	5	EFO_0008592
Disease	basophil count	GALC DHDDS NCF4 EPS15L1 CCDC102A CAPN3 TRNT1 AP5M1 PRKDC	6.71e-03	483	204	9	EFO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDLGLTVEVWNKGLI	UNC13A	56	Q9UPW8
SGLSDIILGKIWDLA	EPS15L1	46	Q9UBC2
IEAILALKGLTVQQW	PGM3	426	O95394
WLIGKVLNAIEDNGL	ARSD	331	P51689
WNDLEKRFQKVGLLE	ATP13A5	141	Q4VNC0
VLNGGKINSDIWKDL	APBB2	356	Q92870
LEEGEKVLNRDWILQ	CRYBG3	2351	Q68DQ2
LAQLLDQIWRTKDAG	CPSF2	246	Q9P2I0
KGNLSRVLEALWELL	BAIAP3	911	O94812
GNGIWELKREEITLL	BMX	406	P51813
HWQLGQKLEGLLRQV	CARMIL2	786	Q6F5E8
LGLQSKDQAEQWLRV	AFAP1L2	251	Q8N4X5
QDSEGKQALIWLLGV	AP4B1	431	Q9Y6B7
RGELSVGQLLKWIDT	ACOT11	61	Q8WXI4
RKVIQTQGEWELLGI	HTR3C	206	Q8WXA8
QEKGWKVGDLLQAVL	AKAP11	1861	Q9UKA4
ELVGWNLEGLRQQLK	APOA5	116	Q6Q788
ALGKQLNLKLLDNWD	APOA1	61	P02647
WELELVNVLKVQLLG	ANKS1A	806	Q92625
DGNHKLTLGLIWNII	DMD	101	P11532
LQEKLGSLNLRWQEV	DMD	2181	P11532
TLNLRWEELGVKEAQ	CCDC42	71	Q96M95
SLVQLVQGLKDLVWL	ATG2B	1896	Q96BY7
LLTLANIKIWVLTGD	ATP8B2	681	P98198
LVVWKELESLLENEG	DENND4A	1641	Q7Z401
LNIGGKRVNLAIWDT	RAB21	61	Q9UL25
EEVLNDWKLIGNSLG	RAB3GAP1	31	Q15042
EKALLAQLWALQGEV	PDZRN4	171	Q6ZMN7
TQLGLRFKLQAWEVL	NOXA1	111	Q86UR1
ARLGSVLVLWDINKE	SDR16C5	61	Q8N3Y7
LLLRQAADWKAGQLD	ITPRIP	441	Q8IWB1
WTLLGKEELSGSLLQ	MAP4K2	356	Q12851
LVAKQLELELEVVWG	MUC6	141	Q6W4X9
WVINGLLEAKVSLDR	ABCC10	556	Q5T3U5
LVGGDLQVLEKIRWN	PAPSS2	366	O95340
LQVLEKIRWNDGLDQ	PAPSS2	371	O95340
ITWEDLQEIGITKLG	CASKIN1	576	Q8WXD9
LIVFLGIVLGNLWKE	COQ2	341	Q96H96
AVKKGEWILLDEINL	MDN1	826	Q9NU22
LEGKAQWGENLQVTL	MAP1A	2741	P78559
LALNEGVNWLIKNVI	DOLPP1	66	Q86YN1
LESQQLIEKNWLLQG	KIF15	1206	Q9NS87
LIEKNWLLQGQLDDI	KIF15	1211	Q9NS87
WLLQGQLDDIKRQKE	KIF15	1216	Q9NS87
GDIILVLSKVNEEWL	NCF2	481	P19878
WVNGTDLELLKELQQ	GNPTAB	81	Q3T906
KLLEELLVSLQWGRE	BLZF1	266	Q9H2G9
NGKLRQWLIDQIDSG	IRF4	21	Q15306
FLENLLVTWKQVGLE	ALAS1	586	P13196
KNILSQIVDIDGIWE	PNLIP	256	P16233
ENATNWIGLRKLQEL	LRRK1	371	Q38SD2
WIGLRKLQELDISDN	LRRK1	376	Q38SD2
GVLDWLIQKGVDLLV	IBTK	66	Q9P2D0
LTDKIGWLDSLGQQI	KCNH7	581	Q9NS40
DEILVIRKGWLTINN	DNM1	516	Q05193
IKLGAGTFQLDQWLR	MNX1	201	P50219
NLTEANLKGESIWKL	SMPDL3A	356	Q92484
LPIEANLVWQLGKDL	HSPH1	596	Q92598
STILALKQGDEVWLQ	C1QTNF2	236	Q9BXJ5
AIVDGNLKLILGLVW	FLNB	101	O75369
LWQIIKIGLFADIEL	PLS3	231	P13797
GEVILGDIWKLNLQT	KLHDC10	336	Q6PID8
DALNRWLGEQLKQLV	PDXDC1	426	Q6P996
LIDGLSGEKIRWTQQ	DNAH8	3356	Q96JB1
QVRDGWLQLLDIETK	EPS8L3	71	Q8TE67
RLKSQDLELSWNLNG	FCER2	101	P06734
FQERLLAVGKWLSIN	FUCA1	351	P04066
KNAITWGDQDLLNII	GXYLT2	306	A0PJZ3
ILLRGTVQEKLNWAF	KCNIP4	151	Q6PIL6
VIFLLSRINKDWLEG	NCF4	196	Q15080
RDSVLTWLLKENLGG	KIF1C	301	O43896
LGDLLKIQLTWEGAS	LIPG	406	Q9Y5X9
EVEELWIGLNDLKLQ	MRC2	436	Q9UBG0
ILWLENALGKLEVEG	GABRA6	11	Q16445
LKLWLKVNGELRQEG	FAHD1	146	Q6P587
GDIWNKLVEVQCLLL	GCN1	136	Q92616
VNGQVLVQLLWALKG	MROH6	216	A6NGR9
GQLEVFREKSLLIWI	AP5M1	376	Q9H0R1
LETLEWLLQKNPQLG	POLE	2271	Q07864
GEAWKELQVKLLELQ	ITGB4	1051	P16144
KRLVVDWTLNIGEQA	BBS9	231	Q3SYG4
VDLEKNQITALGAWL	NLRC5	1801	Q86WI3
LQDLRAWVGNKNLIL	MACF1	3496	Q9UPN3
KTLANILWREEGLGI	FSTL5	436	Q8N475
GKQWLEATIQLGRLS	MALRD1	771	Q5VYJ5
IVLQLKLGDEVWLQV	C1QTNF9	291	P0C862
TALEILDLWKAIDGL	GALP	61	Q9UBC7
KLEGLLIAWFQQIRA	CENPB	76	P07199
KLLTQEQWEVRHGGL	BTAF1	396	O14981
AGQLKWSLELQERLE	DNAH17	586	Q9UFH2
GQFKLLQAEEVARLW	ELK4	31	P28324
LLWGLTQEASVDLKN	FCGBP	16	Q9Y6R7
GLKQIGLDQIWDDLR	CUL1	11	Q13616
QEDLSIWLSGLLGIK	GAS2L3	51	Q86XJ1
GIIALTLEANKNLTW	FURIN	376	P09958
IWKRNGLTLNFLDLE	FSTL4	281	Q6MZW2
KTLANILWREEGLSV	FSTL4	436	Q6MZW2
LSRNIEKLEGELSQW	CCDC102A	276	Q96A19
DGLIQVSIKEWLQLT	CAPNS2	231	Q96L46
NLKWTLERKLEELDG	CCDC57	151	Q2TAC2
SQDVGLWFREQLIKL	ANKMY1	91	Q9P2S6
LLLSGRDWNTLIVGK	PRMT5	71	O14744
VDILQRLGLSWTKAG	COL27A1	46	Q8IZC6
NLLDSKTIQGELGWI	EPHA3	31	P29320
IEGDLTLRKKLWEAQ	DNAH14	926	Q0VDD8
GLQVAWLVVEKNERL	MAP3K20	211	Q9NYL2
LQKDLENEGLVWISL	CDCA2	896	Q69YH5
RLGEDLNKWQALLVQ	DYNC1H1	1071	Q14204
LLRGWEEALENVIKS	HEATR1	636	Q9H583
QLVDTLGAEKFLWIL	HEATR1	1401	Q9H583
IWDSETLLKLQEIGL	EML3	341	Q32P44
IDWDIRGKLLQVNTG	EML5	1131	Q05BV3
QKDTAELLRGLSLWN	FBXL5	161	Q9UKA1
EQEVVWLLAKLGVQS	ATRIP	656	Q8WXE1
LKQAIIQQWLEGTLS	COG2	626	Q14746
TAILGRVNQLLDEKW	COL13A1	86	Q5TAT6
ESVILWLNKNGIQEI	FSHR	171	P23945
DLATLKWILENKAGI	GTF2IRD2	161	Q86UP8
DLATLKWILENKAGI	GTF2IRD2B	161	Q6EKJ0
DLATLKWILENKAGI	GTF2I	166	P78347
EEKRLLWEQLQGLES	GRIPAP1	201	Q4V328
KDGDGIIKLNVLEWL	CAPN3	801	P20807
LLLEVIWILAADGGQ	CA14	6	Q9ULX7
QGLQRVKIIASDNLW	GALC	216	P54803
QGFLQALELKRADWL	DHDDS	311	Q86SQ9
ISKTVAWLNEQLELG	DUSP6	16	Q16828
DKLISGLGSENIRWL	DNAH10	3321	Q8IVF4
DQVILLRAGWNELLI	RXRA	296	P19793
WLKNGAALVLEERTQ	CNTN3	351	Q9P232
ELILRTENGLWLKVE	CYP4F22	511	Q6NT55
EKLLRQVDWGQLDYL	NUBPL	166	Q8TB37
ISLWNILRNNIGKDL	OSBPL3	526	Q9H4L5
DVSLWNILRNNIGKD	OSBPL7	476	Q9BZF2
AEISQWKERGLGNLK	RGPD1	1056	P0DJD0
LDLGQLEGVAWVNKS	IRF3	16	Q14653
ILLGLTENLELWKIF	OR4C6	11	Q8NH72
VNNTAGDDLAKLLWL	MTOR	2291	P42345
DSVLTWLLKDNLGGN	KIF13A	306	Q9H1H9
ALWLTNLLGKEITAE	GAS2	41	O43903
SGLALEWAKALLQEN	RTL1	246	A6NKG5
ILWLKLLLNISSGED	RTTN	2076	Q86VV8
LGLFEELWAAQVKRL	TARS2	36	Q9BW92
TAILEDQLQKLGERW	UTRN	496	P46939
GKEIGALLQQLREQW	TRNT1	401	Q96Q11
NQWILSKLLDAGGDL	TEX14	101	Q8IWB6
LWNEIERLKDKGNFL	STK16	106	O75716
KGNFLTEDQILWLLL	STK16	116	O75716
WLQIRVGVDLDENLK	SLC9A9	486	Q8IVB4
TEKIQLLEGLLESWS	SYNE1	7011	Q8NF91
GQIAKLEEQWLSLNK	SYNE2	4916	Q8WXH0
NFWGKLEKNITRGLE	TDO2	221	P48775
GLKELEISWGLHQIV	SCYL1	111	Q96KG9
SILGQLKAELGNQWI	PLD1	856	Q13393
LKGDLLENGLLFWQE	RGS22	1041	Q8NE09
WLLLSRLEEKIGQLT	PRPF6	746	O94906
NISGWLEKNKDLLNE	MYH15	601	Q9Y2K3
TGEEQLWKELVLFLR	PIK3R6	291	Q5UE93
ALEGKILAVDISIWL	ERCC5	21	P28715
NQVVLWDKIVLRGDN	SPCS3	101	P61009
LLLQVLKELLETWGS	TELO2	331	Q9Y4R8
LILWEKRTALLQGFE	TENM2	1156	Q9NT68
LIELWEGLTVDDVQK	OXCT1	486	P55809
GTQLKDWEGLTSLLL	STAG3L1	171	P0CL83
RLLEWQDKGIFVIQS	PLA2R1	31	Q13018
INDLGTIKLNLEITW	RIPOR2	301	Q9Y4F9
GELQLWLEKQTVLLQ	SPTBN5	906	Q9NRC6
AWLREKNLVALEEGL	SPTBN5	2696	Q9NRC6
EISVQLGLEWNKLSE	SOX30	366	O94993
RLADLKQLWGLLIEE	SPTBN1	1566	Q01082
AVKNQIALWDQLLEG	AATF	226	Q9NY61
IALWDQLLEGRIKLQ	AATF	231	Q9NY61
QGWLRFSEGNILELL	NCAPG	271	Q9BPX3
NWSERKEGLLGLQNL	CLASP2	666	O75122
VGWQLKNLVNALRED	CNKSR2	271	Q8WXI2
DDELRKNVTGILWNL	PKP3	416	Q9Y446
LKLLSLWRIKNGDQD	TNFRSF11B	326	O00300
LWRIKNGDQDTLKGL	TNFRSF11B	331	O00300
KLGNWLAVRIGNELE	TJP2	641	Q9UDY2
LGLLEALLKIGDWQH	THOC2	346	Q8NI27
GLDTLQKSLWIQLLE	UNC80	2156	Q8N2C7
DWEGLTSLLLEKDQN	STAG3	511	Q9UJ98
EVKGLLGLLEELAWN	PLAC9	66	Q5JTB6
QLISEWKQKSLEGRG	PLPPR3	406	Q6T4P5
LRSGNVLEEAKTWLN	TONSL	381	Q96HA7
QGELEKLRKEWNALE	SLMAP	656	Q14BN4
DEVNAAWQRLKGLAL	SPTAN1	231	Q13813
QLEGKWAVLGTLLQE	ZNF398	91	Q8TD17
SWGLVQLVLLAGKLN	SLC12A9	401	Q9BXP2
RGELWLLLSGAINEK	TBC1D9	521	Q6ZT07
LNAISIWKNLLELDA	THUMPD2	106	Q9BTF0
EDLEGLDLQLALAWQ	SMIM44	91	A0A286YF18
REQEVLQGWKELLSA	SPTBN4	1916	Q9H254
KGLLQLQWKQDLDRG	TOMM70	516	O94826
LQWKQDLDRGLELIS	TOMM70	521	O94826
IWGGNVALDNLQIKE	VPS13C	31	Q709C8
LDLGLSVEVWNKGLI	UNC13B	56	O14795
WKVTSEDLILIGNEL	MRPL21	106	Q7Z2W9
ILQLEQGKELWQEGR	ZNF705EP	56	A8MWA4
WEAVAKERLNELGLL	SMUG1	251	Q53HV7
NVLWEEGKAALEQLL	SYMPK	226	Q92797
GLIEWLENTVTLKDL	PRKDC	3801	P78527
WILEQTASLVKQLGL	YAE1	201	Q9NRH1
QLEQGKELWVLNLLG	ZNF251	66	Q9BRH9
LQLSLWGGDVVLSKL	VPS13B	26	Q7Z7G8
ELQDLLSQDWRVKGA	ZNF830	356	Q96NB3
DILEIGAQWSILRKD	PSMD8	146	P48556
LATGLNDGQIKIWEV	WSB2	126	Q9NYS7
NDGQIKIWEVQTGLL	WSB2	131	Q9NYS7
KIWEVQTGLLLLNLS	WSB2	136	Q9NYS7
ESDIEKLIIAAWGQL	TINAG	456	Q9UJW2
VWGLKKNFALLELLE	TRIM23	86	P36406
GELVNELLKSWLKGL	ZNF557	21	Q8N988
RNGSLQEKLWAILQA	PXMP4	56	Q9Y6I8
QLLKDLASKGNLEWL	WDR87	2551	Q6ZQQ6
LFQDEINWRLKEGLV	USP11	136	P51784
VVVWNAQTGEKLLEL	WDR41	66	Q9HAD4
VLQRLDVWLSGGNDL	WDR41	141	Q9HAD4
HLIILWKNGERESGL	WDR41	426	Q9HAD4
LVFALWQQLGAVLKD	WDR81	901	Q562E7
QLEGKWAVLGTLLQE	ZNF783	91	Q6ZMS7
TQNLIRDKAILFWIG	KLRB1	141	Q12918
VLETKWALLQEQGSR	KRT75	176	O95678
DLGSNWLQDNGVKLL	NLRP14	906	Q86W24
WLKRGISALLLNQGD	SLC8A2	616	Q9UPR5
IKLISGWNIDILERG	MYOM3	1006	Q5VTT5
WKRQIDLALLQFVGD	GRIN2A	771	Q12879
GWKRQVDLAILQLFG	GRIN2B	771	Q13224