Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	NfI_DNAbd_pre-N	NFIA NFIX	4.90e-05	4	54	2	PF10524
Domain	CTF_NFI	NFIA NFIX	4.90e-05	4	54	2	PF00859
Domain	CTF_NFI_1	NFIA NFIX	4.90e-05	4	54	2	PS00349
Domain	N-RASSF	RASSF8 RASSF7	4.90e-05	4	54	2	IPR033593
Domain	CTF/NFI	NFIA NFIX	4.90e-05	4	54	2	IPR000647
Domain	CTF_NFI_2	NFIA NFIX	4.90e-05	4	54	2	PS51080
Domain	CTF/NFI_DNA-bd_N	NFIA NFIX	4.90e-05	4	54	2	IPR019548
Domain	CTF/NFI_DNA-bd_CS	NFIA NFIX	4.90e-05	4	54	2	IPR019739
Domain	CTF/NFI_DNA-bd-dom	NFIA NFIX	4.90e-05	4	54	2	IPR020604
Domain	RA	RASSF6 RASSF8 RASSF7	9.70e-05	31	54	3	SM00314
Domain	RA	RASSF6 RASSF8 RASSF7	1.52e-04	36	54	3	PF00788
Domain	RA	RASSF6 RASSF8 RASSF7	1.66e-04	37	54	3	PS50200
Domain	WASP_C	PAK4 PAK6	1.71e-04	7	54	2	IPR011026
Domain	RA_dom	RASSF6 RASSF8 RASSF7	2.09e-04	40	54	3	IPR000159
Domain	XK_rel	XKR6 XKR4	4.44e-04	11	54	2	IPR018629
Domain	XK-related	XKR6 XKR4	4.44e-04	11	54	2	PF09815
Domain	MAD_homology1_Dwarfin-type	NFIA NFIX	5.32e-04	12	54	2	IPR003619
Domain	DWA	NFIA NFIX	5.32e-04	12	54	2	SM00523
Domain	MH1	NFIA NFIX	5.32e-04	12	54	2	PF03165
Domain	PBD	PAK4 PAK6	9.59e-04	16	54	2	SM00285
Domain	PBD	PAK4 PAK6	1.09e-03	17	54	2	PF00786
Domain	CRIB	PAK4 PAK6	1.51e-03	20	54	2	PS50108
Domain	CRIB_dom	PAK4 PAK6	1.66e-03	21	54	2	IPR000095
Domain	Ubiquitin-rel_dom	RASSF6 RASSF8 RASSF7 USP47	1.96e-03	184	54	4	IPR029071
Domain	ATP_grasp_subdomain_2	ACACA TTL	3.62e-03	31	54	2	IPR013816
Domain	Ion_trans_dom	KCNQ5 NALCN CACNA1G	4.38e-03	114	54	3	IPR005821
Domain	Ion_trans	KCNQ5 NALCN CACNA1G	4.38e-03	114	54	3	PF00520
Pubmed	Endogenously nitrated proteins in mouse brain: links to neurodegenerative disease.	NFIA VPS16 CRMP1 CKMT1A	9.56e-08	27	55	4	16800626
Pubmed	Single-Cell RNA-Seq Analysis of Retinal Development Identifies NFI Factors as Regulating Mitotic Exit and Late-Born Cell Specification.	NFIA NFIX	7.36e-06	3	55	2	31128945
Pubmed	Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.	NALCN UNC79	7.36e-06	3	55	2	26708753
Pubmed	The RASSF gene family members RASSF5, RASSF6 and RASSF7 show frequent DNA methylation in neuroblastoma.	RASSF6 RASSF7	7.36e-06	3	55	2	22695170
Pubmed	Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).	NALCN UNC79	7.36e-06	3	55	2	30167850
Pubmed	Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.	NALCN UNC79	7.36e-06	3	55	2	21040849
Pubmed	Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.	NALCN UNC79	7.36e-06	3	55	2	32620897
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	KCNQ5 ACACA SYNJ1 MINK1 PAK4 MACF1 RASSF8 PAK6 RASSF7	7.68e-06	861	55	9	36931259
Pubmed	Transcription factor NF 1 expression in involuting mammary gland.	NFIA NFIX	1.47e-05	4	55	2	10959417
Pubmed	Chromosomal localization of the four genes (NFIA, B, C, and X) for the human transcription factor nuclear factor I by FISH.	NFIA NFIX	1.47e-05	4	55	2	7590749
Pubmed	Differential neuronal and glial expression of nuclear factor I proteins in the cerebral cortex of adult mice.	NFIA NFIX	1.47e-05	4	55	2	28295292
Pubmed	Gene regulatory networks controlling vertebrate retinal regeneration.	NFIA NFIX	1.47e-05	4	55	2	33004674
Pubmed	NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation.	NFIA NFIX	1.47e-05	4	55	2	29247144
Pubmed	Nuclear factor one transcription factors as epigenetic regulators in cancer.	NFIA NFIX	1.47e-05	4	55	2	28076901
Pubmed	Altered expression of the developmentally regulated NFI gene family during phorbol ester-induced differentiation of human leukemic cells.	NFIA NFIX	1.47e-05	4	55	2	9052991
Pubmed	Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development.	NFIA NFIX	1.47e-05	4	55	2	9056636
Pubmed	The emerging importance of group II PAKs.	PAK4 PAK6	1.47e-05	4	55	2	20070256
Pubmed	Genomic organization, splice products and mouse chromosomal localization of genes for transcription factor Nuclear Factor One.	NFIA NFIX	1.47e-05	4	55	2	12568726
Pubmed	The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.	NALCN UNC79	1.47e-05	4	55	2	32494638
Pubmed	Control of neurogenic competence in mammalian hypothalamic tanycytes.	NFIA NFIX	2.45e-05	5	55	2	34049878
Pubmed	Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family.	NFIA NFIX	2.45e-05	5	55	2	19706729
Pubmed	Targeted disruption of the gene for the PAK5 kinase in mice.	PAK4 PAK6	3.67e-05	6	55	2	14517284
Pubmed	Absence of the transcription factor Nfib delays the formation of the basilar pontine and other mossy fiber nuclei.	NFIA NFIX	3.67e-05	6	55	2	19107796
Pubmed	Temporal control of a dendritogenesis-linked gene via REST-dependent regulation of nuclear factor I occupancy.	NFIA NFIX	3.67e-05	6	55	2	21270437
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	EIF3B VPS16 RASSF8 USP47 CCDC93	4.88e-05	251	55	5	29778605
Pubmed	NFI in the development of the olfactory neuroepithelium and the regulation of olfactory marker protein gene expression.	NFIA NFIX	5.13e-05	7	55	2	10762365
Pubmed	TGF-β/NF1/Smad4-mediated suppression of ANT2 contributes to oxidative stress in cellular senescence.	NFIA NFIX	5.13e-05	7	55	2	25220407
Pubmed	Expansion of the lateral ventricles and ependymal deficits underlie the hydrocephalus evident in mice lacking the transcription factor NFIX.	NFIA NFIX	6.83e-05	8	55	2	25960350
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	MTMR3 EIF3B TEX10 NEURL4	7.11e-05	139	55	4	25476789
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RBM25 ACACA RRP1B MACF1 NCBP1 TEX10 USP47	7.40e-05	653	55	7	22586326
Pubmed	SKAR links pre-mRNA splicing to mTOR/S6K1-mediated enhanced translation efficiency of spliced mRNAs.	NCBP1 EIF3B	8.78e-05	9	55	2	18423201
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MAN2B2 KCNQ5 ACACA NFIA NFIX MINK1 STAP2 MACF1 SLC1A1 VPS13B	1.01e-04	1489	55	10	28611215
Pubmed	PAK4 kinase is essential for embryonic viability and for proper neuronal development.	PAK4 PAK6	1.10e-04	10	55	2	14517283
Pubmed	Exposure of phosphatidylserine by Xk-related protein family members during apoptosis.	XKR6 XKR4	1.10e-04	10	55	2	25231987
Pubmed	mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis.	NCBP1 EIF3B	1.10e-04	10	55	2	30232453
Pubmed	Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.	GOPC PAK4 SFXN2 MACF1	1.23e-04	160	55	4	31678930
Pubmed	Nfix regulates fetal-specific transcription in developing skeletal muscle.	NFIA NFIX	1.34e-04	11	55	2	20178747
Pubmed	A genome-wide association study of seasonal pattern mania identifies NF1A as a possible susceptibility gene for bipolar disorder.	NFIA NFIX	1.34e-04	11	55	2	22925353
Pubmed	Prognostic implications of genetic variants in advanced non-small cell lung cancer: a genome-wide association study.	LIPC NALCN	1.34e-04	11	55	2	23144319
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FAIM STAG1 SYNJ1 MTIF2 MTMR3 MACF1 NCBP1 USP47 CRMP1	1.71e-04	1285	55	9	35914814
Pubmed	Nuclear factor I coordinates multiple phases of cerebellar granule cell development via regulation of cell adhesion molecules.	NFIA NFIX	1.89e-04	13	55	2	17553984
Pubmed	Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord.	NFIA NFIX	1.89e-04	13	55	2	29106906
Pubmed	The intracellular domain of teneurin-1 induces the activity of microphthalmia-associated transcription factor (MITF) by binding to transcriptional repressor HINT1.	NUBP1 MACF1	1.89e-04	13	55	2	25648896
Pubmed	An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.	ACACA NFIA NFIX AIPL1	1.93e-04	180	55	4	35198878
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	RBM25 RRP1B NFIA VPS16 TEX10 NEURL4	1.93e-04	533	55	6	30554943
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM25 ACACA PAPOLA NFIA MINK1 EIF3B USP47	2.11e-04	774	55	7	15302935
Pubmed	Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.	STK35 DNAH9	2.21e-04	14	55	2	24811271
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	GOPC RRP1B MINK1 PAK4 MTMR3 NCBP1 TEX10 NEURL4	2.31e-04	1049	55	8	27880917
Pubmed	Investigation of variants identified in caucasian genome-wide association studies for plasma high-density lipoprotein cholesterol and triglycerides levels in Mexican dyslipidemic study samples.	LIPC XKR6	2.54e-04	15	55	2	20160193
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SYNJ1 MINK1 PAK4 MACF1 PAK6 CCS	2.64e-04	565	55	6	25468996
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ACACA NFIA MACF1 NCBP1 CACNA1G EIF3B UNC79	2.72e-04	807	55	7	30575818
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM25 RRP1B MACF1 NCBP1 EIF3B TEX10 MRPL49 CRMP1	2.85e-04	1082	55	8	38697112
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ESCO2 PAPOLA SYNJ1 PAK4 MACF1 VPS13B CRMP1 NCKAP1L	2.88e-04	1084	55	8	11544199
Pubmed	Exon structure of the nuclear factor I DNA-binding domain from C. elegans to mammals.	NFIA NFIX	2.90e-04	16	55	2	10087299
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	ACACA VPS16 NEURL4 USP47	3.59e-04	212	55	4	33853758
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	RBM25 RRP1B MACF1 EIF3B VPS16 CCDC93 CKMT1A	3.64e-04	847	55	7	35235311
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	ACACA SYNJ1 NUBP1 RASSF8 NEURL4 RASSF7 USP47	3.80e-04	853	55	7	28718761
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	ACACA GOPC PAPOLA NUBP1 MACF1 NCBP1 EIF3B USP47 CRMP1	4.28e-04	1455	55	9	22863883
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	GOPC RRP1B MTIF2 MINK1 PAK4 MACF1 MRPL49 NEURL4 VPS13B	5.02e-04	1487	55	9	33957083
Pubmed	Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.	RRP1B XKR6	5.06e-04	21	55	2	25017104
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	RBM25 PAK4 MTMR3 EIF3B CKMT1A	5.31e-04	420	55	5	28065597
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	GOPC RRP1B RASSF6 MINK1 PAK4 EIF3B TEX10	5.58e-04	910	55	7	36736316
Pubmed	Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts.	MTIF2 TTL	6.08e-04	23	55	2	20468071
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	PAK4 EIF3B USP47 CRMP1	6.28e-04	246	55	4	15345747
Pubmed	The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.	ACACA EIF3B	6.63e-04	24	55	2	24798327
Pubmed	Morphogenetic lung defects of JSAP1-deficient embryos proceeds via the disruptions of the normal expressions of cytoskeletal and chaperone proteins.	NFIA NFIX	7.20e-04	25	55	2	18324732
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SYNJ1 MINK1 MACF1 TEX10 UNC79 NEURL4 CRMP1	7.79e-04	963	55	7	28671696
Pubmed	SOX9 and SOX10 control fluid homeostasis in the inner ear for hearing through independent and cooperative mechanisms.	PHEX GJB2	8.40e-04	27	55	2	36343245
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	RRP1B RASSF6 RASSF8 RASSF7	8.88e-04	270	55	4	24366813
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	ESCO2 STAG1 PAK4 MACF1 CRMP1	8.97e-04	472	55	5	38943005
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	RBM25 RRP1B NCBP1 TEX10 MRPL49 CKMT1A	8.98e-04	713	55	6	29802200
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SYNJ1 MINK1 MACF1 CRMP1	1.03e-03	281	55	4	28706196
Pubmed	KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.	ACACA RRP1B NCBP1 MRPL49	1.03e-03	281	55	4	26725010
Pubmed	Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning.	NFIA NFIX	1.04e-03	30	55	2	23042737
Pubmed	Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.	LIPC STAG1	1.04e-03	30	55	2	19936222
Pubmed	The transcription factor gene Nfib is essential for both lung maturation and brain development.	NFIA NFIX	1.04e-03	30	55	2	15632069
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GOPC RRP1B PAK4 AIPL1 RASSF8 SLC1A1 NEURL4 CCDC93	1.06e-03	1321	55	8	27173435
Pubmed	HERC2 Facilitates BLM and WRN Helicase Complex Interaction with RPA to Suppress G-Quadruplex DNA.	EIF3B NEURL4	1.11e-03	31	55	2	30279242
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RBM25 RRP1B MACF1 NCBP1 EIF3B TEX10 NEURL4	1.11e-03	1024	55	7	24711643
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MAN2B2 MTIF2 MTMR3 EIF3B NEURL4 CCDC93	1.20e-03	754	55	6	33060197
Pubmed	The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor.	NFIA NFIX	1.26e-03	33	55	2	26071364
Cytoband	3q22.3	FAIM STAG1	4.15e-04	25	55	2	3q22.3
GeneFamily	Ras association domain family	RASSF6 RASSF8 RASSF7	4.91e-07	10	30	3	1198
GeneFamily	Blood group antigens\|XK related family	XKR6 XKR4	1.45e-04	11	30	2	955
GeneFamily	Phosphoinositide phosphatases	SYNJ1 MTMR3	1.28e-03	32	30	2	1079
ToppCell	Cerebellum-Neuronal\|Cerebellum / BrainAtlas - Mouse McCarroll V32	NALCN XKR4 UNC79 CRMP1 CKMT1A	3.46e-06	187	55	5	61b9d6eb131a674598aa8409d7fa909c8765442d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA STAG1 NFIA XKR6 VPS13B	4.68e-06	199	55	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA RASSF7 CCDC93 CKMT1A	5.26e-05	166	55	4	13027ae342994db4540e64eb910df1f42b160931
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACA RASSF7 CCDC93 CKMT1A	5.26e-05	166	55	4	b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	NFIA NFIX RASSF8 SLC1A1	5.77e-05	170	55	4	4cd3b7e43a061948084c01713ae141b5c2c07d89
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	NFIA NFIX RASSF8 SLC1A1	5.77e-05	170	55	4	36c9f7f98612a72dc511c8da4358d67444f6bcf4
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GIMAP1 PAK6 RASSF7 CRMP1	6.04e-05	172	55	4	30f4979abf0218618a56afb06aa6afc23ad838ec
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-secretory_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIPC TTL PAK6 CRMP1	6.18e-05	173	55	4	766e712e4db440468a32971459c1d3354add611f
ToppCell	facs-Large_Intestine-Proximal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIPC TTL PAK6 CRMP1	6.18e-05	173	55	4	40ef91afb366e87b5ba2951d2578ebfe04d042c0
ToppCell	facs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB2 RASSF6 RASSF7 CKMT1A	6.46e-05	175	55	4	eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCell	facs-Trachea-nan-18m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB2 RASSF6 RASSF7 CKMT1A	6.46e-05	175	55	4	3883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJB2 PAK6 RASSF7 CKMT1A	7.85e-05	184	55	4	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GJB2 PAK6 RASSF7 CKMT1A	7.85e-05	184	55	4	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	droplet-Spleen-nan-24m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB2 AIPL1 STK35 CRMP1	7.85e-05	184	55	4	b998803180322a5ea2b567928dea531c26816c3c
ToppCell	Substantia_nigra-Neuronal\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	SYNJ1 UNC79 CRMP1 CKMT1A	8.18e-05	186	55	4	3f889083fcffe516388e9b03a5e23af2010ced33
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASSF6 PAK6 RASSF7 CKMT1A	8.52e-05	188	55	4	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASSF6 PAK6 RASSF7 CKMT1A	8.52e-05	188	55	4	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	E16.5-samps-Mesenchymal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	NFIA NFIX MACF1 CACNA1G	8.52e-05	188	55	4	3f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	NALCN RASSF6 XKR4 CKMT1A	8.88e-05	190	55	4	2375e604eacd38f61f3e661ba2f76d286fcceca7
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NALCN RASSF6 XKR4 CKMT1A	8.88e-05	190	55	4	b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB2 STAP2 SLC1A1 CKMT1A	9.62e-05	194	55	4	550e61a40be2baa59520aaf5912bb99ad094ba15
ToppCell	Bronchial-NucSeq\|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA STAG1 XKR6 VPS13B	1.00e-04	196	55	4	ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA STAG1 XKR6 VPS13B	1.04e-04	198	55	4	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJB2 RASSF6 STAP2 CKMT1A	1.04e-04	198	55	4	89ec1e760a193441092571475cc66a3b425f232e
ToppCell	3'-Broncho-tracheal-Epithelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GJB2 RASSF6 STAP2 CKMT1A	1.04e-04	198	55	4	aa6e7218ee6230902854e66c444b544218b30c0e
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNQ5 XKR6 XKR4 UNC79	1.04e-04	198	55	4	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GJB2 RASSF6 STAP2 CKMT1A	1.06e-04	199	55	4	974f71b56f66243c78f2f297a1540e0e186df530
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	LIPC MINK1 MACF1 XKR6	9.42e-05	127	55	4	EFO_0008595, EFO_0020947
Disease	Abnormality of refraction	KCNQ5 RRP1B NFIA NFIX MTMR3 STK35 CRMP1	2.44e-04	673	55	7	HP_0000539
Disease	sphingomyelin 14:0 measurement	PAPOLA PAK6	4.56e-04	17	55	2	EFO_0010390
Disease	ischemia (biomarker_via_orthology)	GJB2 LIPC	5.12e-04	18	55	2	DOID:326 (biomarker_via_orthology)
Disease	sensorineural hearing loss (implicated_via_orthology)	DNAH9 CCS	5.72e-04	19	55	2	DOID:10003 (implicated_via_orthology)
Disease	cholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement	LIPC STAG1 MACF1 XKR6	1.10e-03	243	55	4	EFO_0004612, EFO_0020944
Disease	brain aneurysm	MINK1 MTMR3 XKR6	1.24e-03	113	55	3	EFO_0003870
Disease	Intellectual Disability	KCNQ5 STAG1 NFIA MACF1 CACNA1G	1.46e-03	447	55	5	C3714756
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	LIPC MACF1 XKR6	1.51e-03	121	55	3	EFO_0008595, EFO_0020943
Disease	sleep duration, high density lipoprotein cholesterol measurement	LIPC STAG1 MACF1	1.51e-03	121	55	3	EFO_0004612, EFO_0005271
Disease	heart conduction disease (implicated_via_orthology)	PHEX KCNQ5	1.63e-03	32	55	2	DOID:10273 (implicated_via_orthology)
Disease	C-reactive protein measurement, high density lipoprotein cholesterol measurement	LIPC STAG1	1.84e-03	34	55	2	EFO_0004458, EFO_0004612

Protein segments in the cluster

Peptide	Gene	Start	Entry
VDVVEMKETIIAFAW	EIF3B	556	P55884
IIIGNMFKLEVWEIL	AIPL1	61	Q9NZN9
AMLRRWFVEVEGTVK	ACACA	2246	Q13085
FRIMILVVAAKEVWG	GJB2	31	P29033
VWRLDLVMVILFKGI	NFIA	126	Q12857
AAMELKVWVDGIQRV	RASSF7	6	Q02833
MELKVWVDGVQRIVC	RASSF8	1	Q8NHQ8
DEEAEVFIVKMWRLL	RBM25	816	P49756
LIVEGMLDIFWGVKR	RASSF6	86	Q6ZTQ3
GGVSMFRWLEVLEKE	GOPC	26	Q9HD26
GMIKQFLRDVDWGEV	NUBP1	151	P53384
EVDIWSLGIMVIEMV	PAK6	581	Q9NQU5
VWRLDLVMVILFKGI	NFIX	126	Q14938
ISVWAARAKEEGIVM	MATN4	506	O95460
EGKLHVLRVMFEVWR	NCBP1	581	Q09161
VEVWIGMTIEELARA	MTIF2	91	P46199
VMIVVFGLEFIIRIW	KCNQ5	166	Q9NR82
LSVEVMERWIIIGFL	NCKAP1L	251	P55160
ILFKEWQDMPVDDVI	NIPA2	266	Q8N8Q9
LDVDIGELIMIKFKW	LIPC	406	P11150
VEEEWGKLIIEMLER	MACF1	401	Q9UPN3
EEFRTMWVIGLVFKK	PAPOLA	431	P51003
QWLVKRAIETKEEMG	CCDC93	121	Q567U6
RDMFGEDVLKWMVIV	GIMAP1	136	Q8WWP7
EDVLKWMVIVFTRKE	GIMAP1	141	Q8WWP7
AIFQVITLEGWVDIM	CACNA1G	346	O43497
VVYVDGKEEIRKEWM	FAIM	31	Q9NVQ4
FRMEDEQLKVWDVIG	CCS	181	O14618
ERVVAEFWDGKIVLV	ESCO2	426	Q56NI9
KAAVPAWEAVEMEIV	MAN2B2	641	Q9Y2E5
EPIKVFDGWMKIDIR	DNAH9	1076	Q9NYC9
IAGKIIEVEDWEIFR	SLC1A1	266	P43005
NGIEERMTVVWDKAV	CRMP1	356	Q14194
LFEIVIQKMVDRWSG	NEURL4	761	Q96JN8
KEVERLIQERGWEFM	CKMT1A	291	P12532
RTIEGFQVLVEMEWL	MTMR3	436	Q13615
VDIWSLGIMVIEMVD	PAK4	496	O96013
IMGWGEKAIEIRSVE	MINK1	1266	Q8N4C8
REMWKGFILTVVELR	STAP2	106	Q9UGK3
VVVVEDIKRWKTMLE	TCEANC2	36	Q96MN5
GWEESRIKVFLDVLM	RRP1B	136	Q14684
VFVSERELDWAKVMV	SFXN2	36	Q96NB2
GEVILIRFVEDKMWV	SYNJ1	926	O43426
IRFVEDKMWVTFLEG	SYNJ1	931	O43426
QMTVIRKVEGDIWAL	MRPL49	106	Q13405
SKWEEILFNMVVGIV	XKR6	411	Q5GH73
GIIIWAMIERITFID	STK35	441	Q8TDR2
VVVAWERRLMVVGDA	VPS16	281	Q9H269
WEVFLEVLDGVEKMK	USP47	1206	Q96K76
TKWEEIVFDMVVGII	XKR4	426	Q5GH76
EELVEGVRWAFIDML	PHEX	436	P78562
WIEMIRKFVTETLED	TEX10	456	Q9NXF1
EIRAICIEEIGVWMK	STAG1	306	Q8WVM7
ERMKEFIGIVWNAVK	VPS13B	1051	Q7Z7G8
GFDFMVDEELKVWLI	TTL	316	Q8NG68
DWKMRFEAVEKVAVI	UNC79	1056	Q9P2D8
VLFRIVTGEDWNKIM	NALCN	1381	Q8IZF0