Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMA3 LAMA5 FBN2 IGFBP6 EDIL3 LTBP4

1.38e-06188386GO:0005201
GeneOntologyMolecularFunctioncalcium ion binding

LRP1 CD93 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

8.59e-06749389GO:0005509
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP12

4.16e-0416382GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP12

7.24e-0421382GO:0030228
GeneOntologyMolecularFunctiontransforming growth factor beta binding

LTBP3 LTBP4

1.11e-0326382GO:0050431
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMA3 LAMA5 LTBP3 FBN2 MEGF6 IGFBP6 EDIL3 LTBP4

2.09e-06530358GO:0062023
GeneOntologyCellularComponentextracellular matrix

LAMA3 LAMA5 LTBP3 FBN2 MEGF6 IGFBP6 EDIL3 LTBP4

1.00e-05656358GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMA3 LAMA5 LTBP3 FBN2 MEGF6 IGFBP6 EDIL3 LTBP4

1.02e-05658358GO:0030312
GeneOntologyCellularComponentlaminin-5 complex

LAMA3 LAMA5

1.63e-054352GO:0005610
GeneOntologyCellularComponentlaminin complex

LAMA3 LAMA5

1.22e-0410352GO:0043256
GeneOntologyCellularComponentmicrofibril

FBN2 LTBP4

2.10e-0413352GO:0001527
HumanPhenoHoarse cry

LAMA3 DLK1 LTBP4

5.81e-0615133HP:0001615
HumanPhenoHoarse voice

LAMA3 LRP12 DLK1 LTBP3 LTBP4

2.92e-05159135HP:0001609
HumanPhenoHypoplastic acetabulae

LRP1 LAMA5

5.99e-055132HP:0003274
HumanPhenoAbnormal larynx morphology

LAMA3 LRP12 DLK1 LTBP3 LTBP4

9.04e-05201135HP:0025423
DomainGAGE

GAGE4 GAGE5 GAGE6 GAGE12H GAGE2A GAGE1 GAGE13 GAGE12F GAGE12I GAGE2E GAGE12J

3.21e-24244111PF05831
DomainGAGE_fam

GAGE4 GAGE5 GAGE6 GAGE12H GAGE2A GAGE1 GAGE13 GAGE12F GAGE12I GAGE2E GAGE12J

5.73e-24254111IPR008625
DomainEGF-like_dom

LRP1 PCSK5 LAMA3 CD93 LAMA5 ADAM29 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

3.89e-152494113IPR000742
DomainEGF

LRP1 PCSK5 LAMA3 CD93 LAMA5 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

6.80e-142354112SM00181
DomainEGF-like_CS

LRP1 LAMA3 CD93 LAMA5 ADAM29 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

2.37e-132614112IPR013032
DomainEGF_2

LRP1 LAMA3 CD93 LAMA5 ADAM29 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

2.84e-132654112PS01186
DomainASX_HYDROXYL

LRP1 CD93 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

7.61e-13100419PS00010
DomainGrowth_fac_rcpt_

LRP1 PCSK5 LAMA3 CD93 LAMA5 LTBP3 FBN2 MEGF6 IGFBP6 LTBP4

1.11e-121564110IPR009030
DomainEGF-type_Asp/Asn_hydroxyl_site

LRP1 CD93 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

1.30e-12106419IPR000152
DomainGAGE

GAGE4 GAGE6 GAGE12H GAGE2A GAGE1 GAGE12F

2.03e-1219416SM01379
DomainGAGE

GAGE4 GAGE6 GAGE12H GAGE2A GAGE1 GAGE12F

2.03e-1219416IPR031320
DomainEGF_1

LRP1 LAMA3 LAMA5 ADAM29 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

5.45e-122554111PS00022
DomainEGF_3

LRP1 CD93 ADAM29 DLK1 LTBP3 FBN2 MEGF6 NRXN1 EDIL3 LTBP4

6.54e-112354110PS50026
DomainEGF_CA

LRP1 CD93 DLK1 LTBP3 FBN2 MEGF6 EDIL3 LTBP4

2.10e-10122418SM00179
DomainEGF-like_Ca-bd_dom

LRP1 CD93 DLK1 LTBP3 FBN2 MEGF6 EDIL3 LTBP4

2.39e-10124418IPR001881
DomainEGF_Ca-bd_CS

LRP1 CD93 LTBP3 FBN2 MEGF6 EDIL3 LTBP4

1.59e-0997417IPR018097
DomainEGF_CA

LRP1 CD93 LTBP3 FBN2 MEGF6 EDIL3 LTBP4

1.84e-0999417PS01187
DomainEGF_CA

LRP1 CD93 LTBP3 FBN2 MEGF6 LTBP4

3.16e-0886416PF07645
DomaincEGF

LRP1 CD93 LTBP3 FBN2

2.88e-0726414IPR026823
DomaincEGF

LRP1 CD93 LTBP3 FBN2

2.88e-0726414PF12662
DomainEGF

LRP1 CD93 DLK1 MEGF6 NRXN1 EDIL3

3.10e-07126416PF00008
DomainTB

LTBP3 FBN2 LTBP4

3.42e-077413PF00683
DomainhEGF

LTBP3 FBN2 MEGF6 EDIL3

3.94e-0728414PF12661
Domain-

LTBP3 FBN2 LTBP4

5.46e-0784133.90.290.10
DomainTB

LTBP3 FBN2 LTBP4

8.17e-079413PS51364
DomainTB_dom

LTBP3 FBN2 LTBP4

8.17e-079413IPR017878
DomainLaminin_aI

LAMA3 LAMA5

4.68e-055412IPR009254
DomainLaminin_I

LAMA3 LAMA5

4.68e-055412PF06008
DomainLaminin_II

LAMA3 LAMA5

4.68e-055412PF06009
DomainLaminin_domII

LAMA3 LAMA5

4.68e-055412IPR010307
DomainLaminin_EGF

LAMA3 LAMA5 MEGF6

6.12e-0535413PF00053
DomainEGF_Lam

LAMA3 LAMA5 MEGF6

6.12e-0535413SM00180
DomainLAM_G_DOMAIN

LAMA3 LAMA5 NRXN1

7.85e-0538413PS50025
DomainLaminin_EGF

LAMA3 LAMA5 MEGF6

7.85e-0538413IPR002049
DomainLaminin_G_2

LAMA3 LAMA5 NRXN1

9.17e-0540413PF02210
DomainLamG

LAMA3 LAMA5 NRXN1

1.22e-0444413SM00282
DomainLAMININ_IVA

LAMA3 LAMA5

1.31e-048412PS51115
DomainLaminin_B

LAMA3 LAMA5

1.31e-048412PF00052
DomainLamB

LAMA3 LAMA5

1.31e-048412SM00281
DomainLaminin_IV

LAMA3 LAMA5

1.31e-048412IPR000034
DomainLdl_recept_a

LRP1 TMPRSS9 LRP12

1.31e-0445413PF00057
Domain-

LRP1 TMPRSS9 LRP12

1.40e-04464134.10.400.10
DomainLDLRA_1

LRP1 TMPRSS9 LRP12

1.59e-0448413PS01209
DomainLDrepeatLR_classA_rpt

LRP1 TMPRSS9 LRP12

1.69e-0449413IPR002172
DomainLDLa

LRP1 TMPRSS9 LRP12

1.69e-0449413SM00192
DomainLDLRA_2

LRP1 TMPRSS9 LRP12

1.69e-0449413PS50068
DomainLaminin_G

LAMA3 LAMA5 NRXN1

2.79e-0458413IPR001791
DomainEGF_extracell

DLK1 MEGF6 EDIL3

3.08e-0460413IPR013111
DomainEGF_2

DLK1 MEGF6 EDIL3

3.08e-0460413PF07974
DomainLAMININ_NTER

LAMA3 LAMA5

5.53e-0416412PS51117
DomainLaminin_N

LAMA3 LAMA5

5.53e-0416412PF00055
DomainLaminin_N

LAMA3 LAMA5

5.53e-0416412IPR008211
DomainLamNT

LAMA3 LAMA5

5.53e-0416412SM00136
DomainGalactose-bd-like

PCSK5 LAMA5 EDIL3

1.15e-0394413IPR008979
Domain-

LAMA3 LAMA5 NRXN1

1.18e-03954132.60.120.200
DomainEGF_LAM_2

LAMA3 LAMA5

1.97e-0330412PS50027
DomainEGF_LAM_1

LAMA3 LAMA5

1.97e-0330412PS01248
DomainLDLR_class-A_CS

LRP1 LRP12

3.48e-0340412IPR023415
Domain-

PCSK5 EDIL3

1.12e-02734122.60.120.260
DomainConA-like_dom

LAMA3 LAMA5 NRXN1

1.22e-02219413IPR013320
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMA3 LAMA5 LTBP3 FBN2 NRXN1 LTBP4

1.11e-05300256M610
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP3 FBN2 LTBP4

2.36e-0532253MM14854
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

LTBP3 FBN2 LTBP4

3.68e-0537253M27134
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP3 FBN2 LTBP4

4.32e-0539253MM14601
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

LTBP3 FBN2 LTBP4

6.22e-0544253M26969
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP3 LTBP4

8.40e-058252M47850
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMA3 LAMA5 NRXN1

1.50e-0459253M27218
PathwayPID_INTEGRIN4_PATHWAY

LAMA3 LAMA5

1.64e-0411252M158
PathwayWP_NRXN1_DELETION_SYNDROME

GRIN3B NRXN1

4.54e-0418252M48098
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LTBP3 FBN2 MEGF6 LTBP4

1.02e-03258254MM14572
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA3 LAMA5

1.27e-0330252M27772
PathwayREACTOME_LAMININ_INTERACTIONS

LAMA3 LAMA5

1.27e-0330252M27216
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA3 LAMA5

1.54e-0333252M39503
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

LAMA3 LAMA5 FBN2

1.88e-03140253M587
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP3 LTBP4

2.04e-0338252MM14874
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA3 LAMA5

2.37e-0341252M27778
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP12

2.85e-0345252MM15344
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

LAMA3 LAMA5

2.98e-0346252M239
PathwayREACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS

LTBP3 LTBP4

3.11e-0347252M646
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP12

3.24e-0348252M27642
Pubmed

An overview of the GAGE cancer/testis antigen family with the inclusion of newly identified members.

GAGE4 GAGE5 GAGE6 GAGE7 GAGE2B GAGE10 GAGE12H GAGE1 GAGE13 GAGE12F GAGE12I GAGE2E GAGE12J

3.22e-3420451318179644
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

GAGE5 GAGE6 GAGE7 GAGE12G GAGE2B GAGE10 GAGE1 GAGE13 GAGE12F GAGE12I GAGE2E GAGE12J

3.81e-20119451228625976
Pubmed

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

GAGE4 GAGE5 GAGE6 GAGE2B GAGE2A GAGE1 GAGE12I

1.34e-1994577544395
Pubmed

Isolation and characterization of PAGE-1 and GAGE-7. New genes expressed in the LNCaP prostate cancer progression model that share homology with melanoma-associated antigens.

GAGE4 GAGE5 GAGE6 GAGE7 GAGE1 GAGE12I GAGE2E

4.45e-19104579651357
Pubmed

Characterization of the GAGE genes that are expressed in various human cancers and in normal testis.

GAGE4 GAGE5 GAGE6 GAGE7 GAGE1 GAGE12I GAGE2E

1.22e-181145710397259
Pubmed

The DNA sequence of the human X chromosome.

GAGE7 GAGE2B GAGE10 GAGE12H GAGE2A GAGE13 GAGE12I GAGE2E GAGE12J

2.30e-0940745915772651
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP1 LRP12 LTBP3 FBN2 NRXN1

3.52e-087145533541421
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

LRP1 PCSK5 LTBP3 MEGF6 LTBP4

4.52e-0711845521078624
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

LAMA3 LAMA5 LTBP3 EDIL3 LTBP4

1.30e-0614645527068509
Pubmed

GAGE7B promotes tumor metastasis and growth via activating the p38δ/pMAPKAPK2/pHSP27 pathway in gastric cancer.

GAGE12F GAGE12I

1.64e-06245230871606
Pubmed

Control of lung development by latent TGF-β binding proteins.

LTBP3 LTBP4

1.64e-06245220945348
Pubmed

In situ-RT-PCR and immunohistochemistry for the localisation of the mRNA of the alpha 3 chain of laminin and laminin-5 during human organogenesis.

LAMA3 LAMA5

1.64e-06245212382139
Pubmed

Biological function of laminin-5 and pathogenic impact of its deficiency.

LAMA3 LAMA5

1.64e-06245217000025
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMA3 LAMA5 FBN2 MEGF6 LTBP4

3.16e-0617545528071719
Pubmed

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.

LAMA3 LAMA5

4.91e-06345215316072
Pubmed

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine.

LRP1 PLCE1

4.91e-06345227322543
Pubmed

Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.

PCSK5 LTBP3

4.91e-06345221700711
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

LAMA3 LAMA5 FBN2

5.15e-062645334189436
Pubmed

Localization of laminin-5, HD1/plectin, and BP230 in the submandibular glands of developing and adult mice.

LAMA3 LAMA5

9.81e-06445210651091
Pubmed

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.

FBN2 LTBP4

9.81e-06445212429738
Pubmed

Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via alpha3beta1 integrin.

LAMA3 LAMA5

9.81e-06445219752234
Pubmed

Latent transforming growth factor-beta (TGF-beta) binding proteins: orchestrators of TGF-beta availability.

LTBP3 LTBP4

9.81e-06445215611103
Pubmed

The latent transforming growth factor beta binding protein (LTBP) family.

LTBP3 LTBP4

9.81e-06445211104663
Pubmed

Sequential deposition of latent TGF-beta binding proteins (LTBPs) during formation of the extracellular matrix in human lung fibroblasts.

LTBP3 LTBP4

9.81e-06445216157329
Pubmed

Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach.

LAMA3 LAMA5

1.63e-05545211969289
Pubmed

Assessment of the association between genetic polymorphisms in transforming growth factor beta, and its binding protein (LTBP), and the presence, and expansion, of Abdominal Aortic Aneurysm.

LTBP3 LTBP4

1.63e-05545219897194
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA3 LAMA5

1.63e-05545211829758
Pubmed

TRIM28 Controls Genomic Imprinting through Distinct Mechanisms during and after Early Genome-wide Reprogramming.

DLK1 EDIL3

1.63e-05545226527006
Pubmed

Complement component C1q regulates macrophage expression of Mer tyrosine kinase to promote clearance of apoptotic cells.

LRP1 CD93

1.63e-05545222422887
Pubmed

Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney.

LAMA3 LAMA5

1.63e-0554529415429
Pubmed

Differential expression of laminin alpha chains during murine tooth development.

LAMA3 LAMA5

1.63e-0554529389447
Pubmed

HIV-protein-mediated alterations in T cell interactions with the extracellular matrix proteins and endothelium.

LAMA3 LAMA5

2.45e-0564529597096
Pubmed

Pcsk5 is required in the early cranio-cardiac mesoderm for heart development.

PCSK5 EDIL3

2.45e-05645228446132
Pubmed

Specific sequence motif of 8-Cys repeats of TGF-beta binding proteins, LTBPs, creates a hydrophobic interaction surface for binding of small latent TGF-beta.

LTBP3 LTBP4

3.42e-05745210930463
Pubmed

Functional consequence of fibulin-4 missense mutations associated with vascular and skeletal abnormalities and cutis laxa.

LTBP3 LTBP4

4.56e-05845227339457
Pubmed

Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain.

LAMA3 LAMA5

4.56e-0584529852162
Pubmed

Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage.

LAMA3 LAMA5

4.56e-0584528872465
Pubmed

Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis.

LAMA3 LAMA5

4.56e-05845223529140
Pubmed

Expression and localization of laminin-5 subunits during mouse tooth development.

LAMA3 LAMA5

4.56e-0584529489770
Pubmed

Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.

FBN2 MEGF6

5.86e-05945212122015
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMA3 LAMA5 IGFBP6 LTBP4

6.55e-0516745422159717
Pubmed

Human variation in alcohol response is influenced by variation in neuronal signaling genes.

CDK5RAP2 FBN2 NRXN1 PLCE1

7.18e-0517145420201926
Pubmed

Functional consequences of cell type-restricted expression of laminin α5 in mouse placental labyrinth and kidney glomerular capillaries.

LAMA5 EDIL3

7.32e-051045222911783
Pubmed

Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.

LAMA3 LAMA5

7.32e-05104529034910
Pubmed

Placental rescue reveals a sole requirement for c-Myc in embryonic erythroblast survival and hematopoietic stem cell function.

CD93 EDIL3

7.32e-051045218550708
Pubmed

Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung.

LAMA3 LAMA5

8.94e-051145212051813
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA3 LAMA5

8.94e-051145221524702
Pubmed

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival.

LAMA3 LAMA5

8.94e-05114528707838
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

LAMA3 LAMA5

1.07e-041245216750824
Pubmed

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.

LAMA3 LAMA5

1.07e-04124529396756
Pubmed

Fukutin-related protein alters the deposition of laminin in the eye and brain.

LAMA3 LAMA5

1.27e-041345221900571
Pubmed

CCG repeats in cDNAs from human brain.

LRP12 NRXN1

1.47e-04144529921901
Pubmed

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform.

LAMA3 LAMA5

1.47e-04144529151674
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

LAMA3 LAMA5 EDIL3

1.49e-047945318757743
Pubmed

Long form of latent TGF-beta binding protein 1 (Ltbp1L) is essential for cardiac outflow tract septation and remodeling.

LTBP3 LTBP4

1.70e-041545217804598
Pubmed

Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.

LAMA3 LAMA5

1.70e-04154529264260
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA3 LAMA5

1.70e-041545215895400
Pubmed

ADAMTS18 Deficiency Affects Neuronal Morphogenesis and Reduces the Levels of Depression-like Behaviors in Mice.

LAMA3 LAMA5

1.94e-041645230579834
Pubmed

Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.

LAMA3 LAMA5

1.94e-041645217601529
Pubmed

Laminin α1 is essential for mouse cerebellar development.

LAMA5 EDIL3

2.20e-041745221983115
Pubmed

A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.

FBN2 NRXN1

2.20e-041745222832960
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMA3 LAMA5

2.47e-041845211311202
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

LAMA5 FBN2

2.47e-041845239040056
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

LRP1 PCSK5 LAMA5

3.00e-0410045325807483
Pubmed

Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.

LAMA3 LAMA5

3.06e-042045222911573
Pubmed

Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.

PCSK5 LAMA3

3.38e-042145222959728
Pubmed

Schwann cell myelination requires integration of laminin activities.

LAMA5 EDIL3

3.38e-042145222767514
Pubmed

PDGFRβ regulates craniofacial development through homodimers and functional heterodimers with PDGFRα.

LAMA3 LAMA5

3.38e-042145227856617
Pubmed

Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: a yeast two-hybrid approach.

LAMA5 MEGF6 LTBP4

3.56e-0410645318654987
Pubmed

Non-EST-based prediction of novel alternatively spliced cassette exons with cell signaling function in Caenorhabditis elegans and human.

LRP1 RECQL5

4.44e-042445217452356
Pubmed

Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.

LAMA3 LAMA5

5.22e-042645224742657
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

LAMA3 LAMA5

6.50e-042945222613833
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

LAMA5 FBN2 LTBP4

7.20e-0413545328675934
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

LAMA5 LTBP3 MEGF6 IGFBP6 LTBP4

7.63e-0456045521653829
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

LRP1 LAMA5 LRP12 LTBP3 PIGG FBN2 EDIL3

8.29e-04120145735696571
Pubmed

Delayed Hair Follicle Morphogenesis and Hair Follicle Dystrophy in a Lipoatrophy Mouse Model of Pparg Total Deletion.

DLK1 EDIL3

8.43e-043345228964716
Pubmed

Interferon gamma receptor 2 gene variants are associated with liver fibrosis in patients with chronic hepatitis C infection.

LTBP3 LTBP4

1.00e-033645220587546
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

LAMA5 FBN2

1.06e-033745234323105
Pubmed

FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice.

FBN2 IGFBP6

1.12e-033845226134413
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

LRP1 LAMA5 LTBP3 FBN2 LTBP4

1.14e-0361345522268729
Pubmed

Association of gene polymorphisms with chronic kidney disease in Japanese individuals.

LAMA3 PIGG

1.18e-033945219724895
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

LAMA3 LAMA5

1.24e-034045227068110
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

LRP1 LAMA3 LAMA5

1.26e-0316445332409323
InteractionFLT3 interactions

GAGE5 GAGE6 GAGE7 GAGE12G GAGE2B GAGE10 GAGE1 GAGE13 GAGE12F GAGE12I GAGE2E GAGE12J

1.92e-123184312int:FLT3
InteractionGMCL1 interactions

GAGE5 GAGE12G GAGE10 GAGE2A GAGE1 GAGE12I GAGE2E GAGE12J

1.12e-09154438int:GMCL1
InteractionIGFL3 interactions

PCSK5 LAMA3 LAMA5 LRP12 FBN2

5.37e-0775435int:IGFL3
InteractionMFAP5 interactions

LAMA5 FBN2 MEGF6 LTBP4

4.51e-0652434int:MFAP5
InteractionCACNA1A interactions

LRP1 PCSK5 LTBP3 MEGF6 LTBP4

6.24e-06123435int:CACNA1A
InteractionZDHHC15 interactions

LRP1 LRP12 LTBP3 FBN2 NRXN1

6.75e-06125435int:ZDHHC15
InteractionGMCL2 interactions

GAGE5 GAGE12I GAGE2E

6.15e-0536433int:GMCL2
InteractionGAGE12G interactions

GAGE12G GAGE2E

9.28e-057432int:GAGE12G
InteractionFBXO2 interactions

PCSK5 LAMA3 LAMA5 FBN2 EDIL3 LTBP4

2.23e-04411436int:FBXO2
InteractionZFP41 interactions

LRP1 FBN2 LTBP4

2.44e-0457433int:ZFP41
InteractionSLURP1 interactions

PCSK5 LAMA3 LAMA5 PIGG

2.48e-04144434int:SLURP1
InteractionPRG2 interactions

PCSK5 LAMA5 LTBP3 FBN2 LTBP4

3.39e-04285435int:PRG2
InteractionEXOC3L2 interactions

GAGE12G GAGE2E

3.98e-0414432int:EXOC3L2
CytobandXp11.23

GAGE12G GAGE2B GAGE12H GAGE2A GAGE1 GAGE13 GAGE12F GAGE12I GAGE2E GAGE12J

2.65e-18954510Xp11.23
CytobandXp11.4-p11.2

GAGE4 GAGE5 GAGE6 GAGE7

1.21e-116454Xp11.4-p11.2
CytobandEnsembl 112 genes in cytogenetic band chrXp11

GAGE12G GAGE10 GAGE12H GAGE2A GAGE1 GAGE13 GAGE12F GAGE2E GAGE12J

1.05e-10377459chrXp11
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP3 LTBP4

6.97e-064202628
GeneFamilyLaminin subunits

LAMA3 LAMA5

7.62e-0512202626
GeneFamilyLow density lipoprotein receptors

LRP1 LRP12

9.00e-0513202634
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA3 LAMA5 LTBP3 FBN2 IGFBP6 EDIL3 LTBP4

6.82e-09191367MM17059
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMA3 LAMA5 LTBP3 FBN2 IGFBP6 EDIL3 LTBP4

8.16e-09196367M3008
CoexpressionNABA_CORE_MATRISOME

LAMA3 LAMA5 LTBP3 FBN2 IGFBP6 EDIL3 LTBP4

7.36e-08270367MM17057
CoexpressionNABA_CORE_MATRISOME

LAMA3 LAMA5 LTBP3 FBN2 IGFBP6 EDIL3 LTBP4

8.34e-08275367M5884
CoexpressionNABA_MATRISOME

PCSK5 LAMA3 LAMA5 ADAM29 LTBP3 FBN2 MEGF6 IGFBP6 EDIL3 LTBP4

6.91e-0710083610MM17056
CoexpressionNABA_MATRISOME

PCSK5 LAMA3 LAMA5 ADAM29 LTBP3 FBN2 MEGF6 IGFBP6 EDIL3 LTBP4

8.12e-0710263610M5889
CoexpressionDESCARTES_FETAL_THYMUS_STROMAL_CELLS

LRP1 DLK1 FBN2 LTBP4

3.69e-05137364M40313
CoexpressionSATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER

GAGE12G GAGE1 GAGE12F

3.70e-0547363M11213
CoexpressionTABULA_MURIS_SENIS_MAMMARY_GLAND_BASAL_CELL_AGEING

LRP1 IER5 LTBP3 IGFBP6 LTBP4

7.48e-05322365MM3786
CoexpressionGSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP

LTBP3 SNPH PTPRCAP LTBP4

1.51e-04197364M4504
CoexpressionGSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP

PCSK5 LAMA5 LTBP3 SNPH

1.54e-04198364M3104
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LRP1 LAMA3 FBN2 EDIL3

1.60e-04200364M5930
CoexpressionRAY_TARGETS_OF_P210_BCR_ABL_FUSION_UP

GAGE12G GAGE12F

2.17e-0416362M16309
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LAMA5 FBN2 IGFBP6 EDIL3 LTBP4

1.44e-08199376edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 MEGF6 IGFBP6 NRXN1 LTBP4

3.22e-071743759c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 MEGF6 IGFBP6 NRXN1 LTBP4

3.22e-07174375bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LAMA3 CD93 MEGF6 LTBP4

5.11e-07191375b9ae5af426e7a1f2652a47700bb168371bd2dec6
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 FBN2 IGFBP6 EDIL3 LTBP4

5.95e-071973752e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 FBN2 IGFBP6 EDIL3 LTBP4

5.95e-071973751da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCellfacs-Trachea-nan-3m-Mesenchymal-fibroblast|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LTBP3 IGFBP6 LTBP4

6.10e-071983750dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 DLK1 IGFBP6 EDIL3 LTBP4

6.10e-0719837575d104eead681f6bf47c4dd24913cc768c9a1717
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 LAMA5 LTBP3 IGFBP6 LTBP4

6.10e-07198375399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 FBN2 IGFBP6 EDIL3 LTBP4

6.10e-071983754a4566f86c9365a41b4cfd1609eac09bd73b3f34
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LTBP3 FBN2 IGFBP6

6.10e-07198375524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 FBN2 IGFBP6 EDIL3 LTBP4

6.25e-07199375e78f661b40da34768469549b6e755d330be6bbd8
ToppCellBiopsy_IPF-Epithelial-Basal|Biopsy_IPF / Sample group, Lineage and Cell type

LAMA3 LAMA5 IGFBP6 EDIL3 LTBP4

6.41e-072003755cea84581201cee7ba8141b96e65864f4fd67113
ToppCellE16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature|E16.5-samps / Age Group, Lineage, Cell class and subclass

CDK5RAP2 SNPH MEGF6 PLCE1

3.96e-061293745e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 LAMA5 EDIL3 PLCE1

8.83e-06158374e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 LAMA5 EDIL3 PLCE1

8.83e-06158374d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 PCSK5 IGFBP6 LTBP4

1.21e-051713745d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 IGFBP6 LTBP4 PLCE1

1.29e-05174374a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 IGFBP6 LTBP4 PLCE1

1.41e-05178374bcbdd45a2307f8aea14122fa0144b96b1f6eec48
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MEGF6 IGFBP6 LTBP4 PLCE1

1.41e-05178374c413861148129be1ee94f2ceb5999840217eebe5
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 PCSK5 IGFBP6 LTBP4

1.44e-0517937402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 FBN2 EDIL3 PLCE1

1.51e-051813745f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 FBN2 EDIL3 PLCE1

1.51e-05181374c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCellE18.5-samps|World / Age Group, Lineage, Cell class and subclass

LAMA3 LAMA5 DLK1 IGFBP6

1.54e-051823749649f15858d1ede73e068afc59df3ac367b49687
ToppCellBasal|World / shred by cell class for mouse tongue

LAMA3 LAMA5 MEGF6 LTBP4

1.57e-05183374c6729a207526ff4aa48176207b9353176f631fea
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FBN2 NRXN1 EDIL3 PLCE1

1.57e-051833748a799807fbf24456a9811e0c64068187940a2f71
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

LAMA3 LAMA5 EDIL3 PLCE1

1.57e-051833746821dca076318115d360ff426eb1218cfe104063
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 DLK1 IGFBP6 LTBP4

1.61e-0518437401257e5c12e38b849fd3d9496c43ded666249ba5
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 LAMA5 MEGF6 LTBP4

1.61e-05184374f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PCSK5 LAMA5 MEGF6 LTBP4

1.61e-051843748bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCellEndothelial-E|World / shred on cell class and cell subclass (v4)

PCSK5 CD93 MEGF6 LTBP4

1.61e-05184374b4c561924c508536fd2112e91e32176b95fdf63a
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN2 IGFBP6 LTBP4

1.64e-05185374785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN2 IGFBP6 LTBP4

1.64e-0518537497a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DLK1 FBN2 IGFBP6 LTBP4

1.68e-05186374c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN2 IGFBP6 LTBP4

1.68e-0518637494d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LRP1 PCSK5 IGFBP6 LTBP4

1.71e-051873744ea486991f66c29728d127171a07b81404ec0b78
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 CD93 MEGF6 LTBP4

1.71e-05187374e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 IGFBP6 NRXN1 LTBP4

1.75e-05188374c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 FBN2 EDIL3 PLCE1

1.75e-05188374b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 MEGF6 IGFBP6 LTBP4

1.75e-05188374ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 IGFBP6 NRXN1 LTBP4

1.75e-051883741cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA3 FBN2 EDIL3 PLCE1

1.75e-05188374874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellFibroblast-C|World / shred on cell class and cell subclass (v4)

DLK1 FBN2 IGFBP6 LTBP4

1.79e-0518937458e0400fbab5a0755504275aef5cf7986149abab
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 CD93 MEGF6 LTBP4

1.79e-05189374d17e8467699c7ca7694a313c26111f085df5204e
ToppCellMatrixFB-Fibroblast-C|MatrixFB / shred on cell class and cell subclass (v4)

DLK1 FBN2 IGFBP6 LTBP4

1.82e-05190374d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 MEGF6 IGFBP6 LTBP4

1.82e-05190374efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 CD93 MEGF6 LTBP4

1.82e-05190374d87b9e9ca863270a9c7f61674271a6440c97d1f4
ToppCellP03-Endothelial-large_vessel_endothelial_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PCSK5 CD93 MEGF6 LTBP4

1.86e-05191374b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 CD93 MEGF6 LTBP4

1.86e-05191374b270c3dd5952f56b9bdceabe13e298fe6757563b
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 CD93 MEGF6 LTBP4

1.86e-0519137427f23c2254b610abac1a88d0fecff305addde9da
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 DLK1 IGFBP6 LTBP4

1.86e-051913744e4488380379ed29d7898bae4e24221e7c67eb9d
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PCSK5 CD93 MEGF6 LTBP4

1.86e-05191374d162917816dd2e4767c97447c1cddae9397713ab
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 CD93 MEGF6 LTBP4

1.90e-05192374285a9d332a1e07b94f222d4b518dd56928b9e075
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 LTBP4

1.90e-05192374a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 EDIL3

1.90e-05192374b35f0e422070ba9c7c1d9ff3eace4edc10286cde
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 LTBP4

1.90e-05192374eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LTBP3 IGFBP6 LTBP4

1.90e-0519237432acd89617934016cd135d2cc797e8e79ae1b37f
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LTBP3 LTBP4

1.94e-05193374ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LTBP3 LTBP4

1.94e-0519337422c58032e58730715224d7934968ce92d150b0e8
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 IGFBP6 LTBP4

1.94e-05193374f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DLK1 IGFBP6 NRXN1 PLCE1

1.94e-05193374cd45118ced91b10baed3b1068d4673ec99824b86
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 LTBP4

1.94e-05193374d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellfacs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 IGFBP6 LTBP4

1.94e-0519337485faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCellP15-Endothelial-large_vessel_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PCSK5 CD93 MEGF6 LTBP4

1.94e-051933745f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PCSK5 CD93 MEGF6 LTBP4

1.94e-0519337458c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 DLK1 IGFBP6 LTBP4

1.94e-05193374051f61156b0e2e95292b2d8377faf3190b50f264
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LTBP3 LTBP4

1.94e-05193374573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellfacs-MAT-Fat-3m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 IGFBP6 LTBP4

1.94e-05193374110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 IGFBP6 LTBP4

1.98e-05194374da926441053b499cb5107ccb116fb1b3844d82b7
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 IGFBP6 LTBP4

1.98e-0519437454a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 IGFBP6 LTBP4

1.98e-05194374f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

LRP1 PCSK5 IGFBP6 LTBP4

1.98e-05194374234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LTBP3 IGFBP6 LTBP4

2.02e-0519537469a29d03e664b72f32d41876510c62345c3aed31
ToppCellCOVID-19-Heart-Low_count_Fib|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 DLK1 IGFBP6 LTBP4

2.02e-05195374e09590d1f51d5fa57fceb84c9f48f84b23d4d224
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 PCSK5 IGFBP6 LTBP4

2.02e-05195374f54bc4454270ff06e85596f98199372b50d0179f
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 LTBP4

2.02e-05195374613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

LRP1 PCSK5 IGFBP6 LTBP4

2.02e-05195374a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCelldroplet-Heart-nan-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 LTBP4

2.02e-051953749ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

LRP1 MEGF6 IGFBP6 EDIL3

2.02e-0519537478978d85273e5463a7f43e4c121e647fa6aba42b
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LTBP3 IGFBP6 LTBP4

2.02e-051953741cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 LTBP3 IGFBP6 LTBP4

2.02e-051953749cef6f18664518060af7c192310dddce6d70345a
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 IGFBP6 EDIL3

2.06e-05196374fcb275746bf51269ed8ba4cf93edb054a45f1ccd
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 LTBP4 PLCE1

2.06e-05196374b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DLK1 FBN2 IGFBP6 LTBP4

2.06e-05196374eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LTBP3 LTBP4 PLCE1

2.06e-05196374787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 FBN2 IGFBP6 LTBP4

2.10e-051973742cb1f557ce1400398975de94638126b4522567f3
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 IGFBP6 EDIL3 LTBP4

2.10e-05197374467e7cbf511d3bcc701923603032aaf0bba2736d
ToppCellBronchial_Brush-Epithelial-Basal_1|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MEGF6 IGFBP6 EDIL3 LTBP4

2.10e-05197374f5d87824c0020c95d89e069fd9f70b49e5d5fcea
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 IGFBP6 NRXN1 EDIL3

2.10e-05197374cfd4cc5fb8d7a60dd5c0d2a1a7bad7ba38c19d40
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

DLK1 FBN2 IGFBP6 LTBP4

2.10e-051973749a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 IGFBP6 EDIL3 LTBP4

2.14e-0519837409be07ebfc3e49c3858e9b74605b69cf4fc28b56
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 IGFBP6 EDIL3 LTBP4

2.14e-051983740f4052a59c6bd89dab637d6ef1214460d6cbcf55
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

LAMA3 LTBP3 FBN2 PLCE1

2.14e-0519837485f424cd9bb3117c9e322031024aabb87696ce47
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

DLK1 NRXN1 LTBP4 RECQL5

2.14e-051983740c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCellBronchial_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MEGF6 IGFBP6 EDIL3 LTBP4

2.14e-0519837410a17d7c116dcd6cf847fe6f5d7196d887cad1f9
ToppCellCOVID-19-Heart-Low_count_Fib|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 DLK1 IGFBP6 LTBP4

2.14e-05198374aee3d8757642cd6bbf6dc03e78b3912c6b8e510a
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PCSK5 DLK1 LTBP3 IGFBP6

2.14e-05198374b086af292a508a156266c2d899ba1caf820bf61c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 PCSK5 LTBP3 IGFBP6

2.14e-051983741b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

LAMA3 LTBP3 FBN2 PLCE1

2.14e-051983749b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellfacs-Trachea-3m-Mesenchymal|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 LTBP3 IGFBP6 LTBP4

2.14e-05198374e85ae846e293687fd193f4d565525d8d3bd1faea
ComputationalIntermediate filaments and MT.

LAMA3 LAMA5 SNPH

2.97e-0468213MODULE_438
Drugindene

CDK5RAP2 GAGE4 GAGE5 GAGE6 GAGE1 GAGE2E

6.27e-08120406CID000007219
Drug1ct8

PCSK5 GAGE7 GAGE1 GAGE12I GAGE2E

1.27e-05173405CID000444888
Drug2oym

LRP1 CD93 MCHR1

1.78e-0529403CID015959255
DrugN,N-dibenzylphenylethanolamine

LRP1 LRP12

1.80e-054402CID000048896
DrugAC1Q6AQ7

PCSK5 GAGE7 GAGE1 GAGE12I GAGE2E

1.89e-05188405CID000005515
Diseasecervical artery dissection

LRP1 PLCE1

1.44e-0417312EFO_1000059
Diseasetemperament and character inventory

FBN2 NRXN1

2.91e-0424312EFO_0004825
Diseasemigraine disorder, pulse pressure measurement

LRP1 PLCE1

3.42e-0426312EFO_0005763, MONDO_0005277
Diseasepersonality trait

NRXN1 PLCE1

7.73e-0439312EFO_0004365
Diseasesevere acute respiratory syndrome, COVID-19

LTBP3 MEGF6 NRXN1 EDIL3

1.18e-03447314EFO_0000694, MONDO_0100096
Diseaseoptic cup area measurement

LTBP3 PLCE1

1.59e-0356312EFO_0006940
Diseaseintraocular pressure measurement

PCSK5 LRP12 LTBP3 FBN2

1.90e-03509314EFO_0004695
Diseaseaortic measurement

LRP1 LTBP4 PLCE1

2.29e-03251313EFO_0020865
Diseasemigraine disorder, endometriosis

LRP12 PLCE1

2.68e-0373312EFO_0001065, MONDO_0005277
Diseaseresponse to alcohol

LRP12 PIGG

2.83e-0375312EFO_0005526
DiseaseLung diseases

PCSK5 LTBP4

3.05e-0378312C0024115

Protein segments in the cluster

PeptideGeneStartEntry
GNGVVEEGEECDCGP

ADAM29

401

Q9UKF5
GGPGEGACQDVDECA

CD93

376

Q9NPY3
DGTQCQDVDECVGPG

CD93

421

Q9NPY3
QDVDECVGPGGPLCD

CD93

426

Q9NPY3
PNPCENDGVCTDIGG

DLK1

176

P80370
PEDGQCPLHCEQIGE

CDK5RAP2

1806

Q96SN8
HPQTGCECEDGPDGQ

GAGE1

81

P0DTW1
CGDGSDEENCPVIVP

LRP12

476

Q9Y561
NCNRDGTEPGVCDPG

LAMA3

1406

Q16787
HPQTGCECEDGPDGQ

GAGE7

81

O76087
PPDKLCDGNDDCGDG

LRP1

1161

Q07954
NCGDGTDEEDCEPPT

LRP1

3721

Q07954
HPQTGCECEDGPDGQ

GAGE2E

81

Q4V326
SEVGCDGPGPDHCND

PCSK5

641

Q92824
ADGAQQERCCVPPGE

HHLA2

381

Q9UM44
PQTGCECEDGPDGQE

GAGE2D;

81

Q9UEU5
PQTGCECEDGPDGQE

GAGE2A

81

Q6NT46
PGVADDRCDPDTGQC

LAMA5

546

O15230
PCEAGEEGEGGVCLN

NRXN1

216

Q9ULB1
GKGDICDPNPCENGG

EDIL3

21

O43854
HPQTGCECEDGPDGQ

GAGE12B;

81

A1L429
HPQTGCECEDGPDGQ

GAGE12F

81

P0CL80
HPQTGCECEDGPDGQ

GAGE12G

81

P0CL81
HPQTGCECEDGPDGQ

GAGE12H

81

A6NDE8
HPQTGCECEDGPDGQ

GAGE12I

81

P0CL82
HPQTGCECEDGPDGQ

GAGE12J

81

A6NER3
DGCEPCGNDTFNREP

DNASE1

121

P24855
HPQTGCECEDGPDGQ

GAGE6

81

Q13070
PKTGCECGDGPDGQE

GAGE10

81

A6NGK3
DVNECEAEPCGPGRG

LTBP3

616

Q9NS15
GCQATEEDPLPNCGA

MCHR1

21

Q99705
PTPGGGCQDVDECRN

LTBP4

1041

Q8N2S1
HPQTGCECEDGPDGQ

GAGE13

81

Q4V321
PDICDGGQCTNIPGE

FBN2

1291

P35556
HPQTGCECEDGPDGQ

GAGE5

81

Q13069
VQAGCPGGCVEEEDG

IGFBP6

36

P24592
GFQGEDCGQECPVGT

MEGF6

721

O75095
RDPDEDGQCPAGQLC

GRIN3B

431

O60391
ESGPEAAEPGQICCD

IER5

296

Q5VY09
DDCGNCVPLPGGEEK

PLCE1

211

Q9P212
DPGEGEQQCGEASSP

PTPRCAP

126

Q14761
HPQTGCECEDGPDGQ

GAGE4

81

P0DSO3
PQTGCECEDGPDGQE

GAGE2B

81

Q13066
QVCGTDPESGDRCPE

SNPH

336

O15079
APEAEGACPSCEGVQ

RECQL5

781

O94762
GQEQAEPPQECVECG

ZSCAN10

661

Q96SZ4
DSCQGDSGGPLVCEE

TMPRSS9

381

Q7Z410
CSDPAPRNGGEECQG

UNC5A

266

Q6ZN44
DDGEPPCGLCVEQGH

PIGG

601

Q5H8A4
VDCDSFLCQNPGEPG

ZNF541

506

Q9H0D2