Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF3398

DOCK11 DOCK7 DOCK10 DOCK6

1.75e-096634PF11878
DomainDOCK_C/D_N

DOCK11 DOCK7 DOCK10 DOCK6

1.75e-096634IPR021816
DomainDOCK_C

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634IPR010703
DomainDHR-1_domain

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634IPR027007
DomainDHR_2

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634PS51651
DomainDHR_1

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634PS51650
DomainDOCK-C2

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634PF14429
DomainDHR-2

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634IPR027357
DomainDHR-2

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634PF06920
DomainDOCK

DOCK11 DOCK7 DOCK10 DOCK6

3.81e-0811634IPR026791
DomainSIM_C

SIM1 SIM2

1.12e-052632IPR010578
DomainANKS1

ANKS1B ANKS1A

1.12e-052632IPR033635
DomainSIM_C

SIM1 SIM2

1.12e-052632PF06621
DomainSIM_C

SIM1 SIM2

1.12e-052632PS51302
DomainFerritin-like_SF

FTHL17 MOB3C

9.93e-0414632IPR009078
DomainPAS_fold_3

SIM1 SIM2

2.71e-0323632IPR013655
DomainPAS_3

SIM1 SIM2

2.71e-0323632PF08447
DomainPAS-assoc_C

SIM1 SIM2

2.95e-0324632IPR000700
DomainPAS

SIM1 SIM2

3.20e-0325632PF00989
DomainPAS_fold

SIM1 SIM2

3.20e-0325632IPR013767
DomainPAC

SIM1 SIM2

3.45e-0326632IPR001610
DomainPAC

SIM1 SIM2

3.45e-0326632SM00086
DomainPAC

SIM1 SIM2

3.45e-0326632PS50113
DomainPID

ANKS1B ANKS1A

4.00e-0328632PF00640
DomainPID

ANKS1B ANKS1A

5.20e-0332632PS01179
DomainPAS

SIM1 SIM2

5.20e-0332632SM00091
DomainPAS

SIM1 SIM2

5.86e-0334632IPR000014
DomainPAS

SIM1 SIM2

5.86e-0334632PS50112
DomainSH3

DLG5 ARHGEF38 NEB MYO15A

6.08e-03216634SM00326
DomainSH3

DLG5 ARHGEF38 NEB MYO15A

6.08e-03216634PS50002
DomainSH3_domain

DLG5 ARHGEF38 NEB MYO15A

6.49e-03220634IPR001452
DomainPTB

ANKS1B ANKS1A

8.04e-0340632SM00462
DomainPTB/PI_dom

ANKS1B ANKS1A

8.44e-0341632IPR006020
DomainANK

ANKS1B POTEB2 POTEB ANKS1A

1.02e-02251634SM00248
DomainANK_REPEAT

ANKS1B POTEB2 POTEB ANKS1A

1.05e-02253634PS50088
DomainAnkyrin_rpt-contain_dom

ANKS1B POTEB2 POTEB ANKS1A

1.06e-02254634IPR020683
DomainANK_REP_REGION

ANKS1B POTEB2 POTEB ANKS1A

1.06e-02254634PS50297
PathwayREACTOME_CDC42_GTPASE_CYCLE

DOCK11 DOCK7 DOCK10 DOCK6 SYDE1

1.31e-0594465MM15598
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

DOCK11 DOCK7 DOCK10 DOCK6 ZFPM2

3.62e-05116465MM15715
PathwayPID_CDC42_REG_PATHWAY

DOCK11 DOCK10 DOCK6

1.24e-0430463M83
PathwayREACTOME_CDC42_GTPASE_CYCLE

DOCK11 DOCK7 DOCK10 DOCK6 SYDE1

1.44e-04155465M41808
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

DOCK11 DOCK7 DOCK10 DOCK6 ZFPM2

2.21e-04170465M941
PathwayREACTOME_BETA_OXIDATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS

ACOT8 ACOX1

5.62e-0411462M27298
PathwayREACTOME_BETA_OXIDATION_OF_VERY_LONG_CHAIN_FATTY_ACIDS

ACOT8 ACOX1

5.62e-0411462MM15002
PathwayREACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM

ACOT8 ACOX1

7.94e-0413462MM14821
PathwayREACTOME_ALPHA_LINOLENIC_OMEGA3_AND_LINOLEIC_OMEGA6_ACID_METABOLISM

ACOT8 ACOX1

7.94e-0413462M27114
PathwayREACTOME_PEROXISOMAL_PROTEIN_IMPORT

ACOT8 ACOX1 PEX1

1.13e-0363463M27915
PathwayREACTOME_PEROXISOMAL_PROTEIN_IMPORT

ACOT8 ACOX1 PEX1

1.23e-0365463MM15628
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK11 DOCK7 DOCK10 DOCK6

1.17e-081466412432077
Pubmed

A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.

SIM1 SIM2

3.55e-06266214697214
Pubmed

The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation.

DOCK11 DOCK10

3.55e-06266225729399
Pubmed

Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.

SIM1 SIM2

3.55e-0626629199934
Pubmed

Single-minded--two genes, three chromosomes.

SIM1 SIM2

3.55e-0626629199929
Pubmed

Involvement of Zizimin2/3 in the age-related defect of peritoneal B-1a cells as a source of anti-bacterial IgM.

DOCK11 DOCK10

3.55e-06266229099971
Pubmed

Overexpression of mSim2 gene in the zona limitans of the diencephalon of segmental trisomy 16 Ts1Cje fetuses, a mouse model for trisomy 21: a novel whole-mount based RNA hybridization study.

SIM1 SIM2

3.55e-06266210837894
Pubmed

Physical mapping of the holoprosencephaly critical region in 21q22.3, exclusion of SIM2 as a candidate gene for holoprosencephaly, and mapping of SIM2 to a region of chromosome 21 important for Down syndrome.

SIM1 SIM2

1.06e-0536627485157
Pubmed

cDNA cloning of a murine homologue of Drosophila single-minded, its mRNA expression in mouse development, and chromosome localization.

SIM1 SIM2

1.06e-0536628561800
Pubmed

ANKS1A regulates LDL receptor-related protein 1 (LRP1)-mediated cerebrovascular clearance in brain endothelial cells.

ANKS1B ANKS1A

1.06e-05366238123547
Pubmed

Identification of phosphotyrosine binding domain-containing proteins as novel downstream targets of the EphA8 signaling function.

ANKS1B ANKS1A

1.06e-05366217875921
Pubmed

Roles of the DOCK-D family proteins in a mouse model of neuroinflammation.

DOCK11 DOCK10

1.06e-05366232241915
Pubmed

Characterization of human variants in obesity-related SIM1 protein identifies a hot-spot for dimerization with the partner protein ARNT2.

SIM1 SIM2

1.06e-05366224814368
Pubmed

Characterization of msim, a murine homologue of the Drosophila sim transcription factor.

SIM1 SIM2

1.06e-0536628661115
Pubmed

Sim1 and Sim2 expression during chick and mouse limb development.

SIM1 SIM2

2.12e-05466219123137
Pubmed

Members of the bHLH-PAS family regulate Shh transcription in forebrain regions of the mouse CNS.

SIM1 SIM2

2.12e-05466211023872
Pubmed

Two murine homologs of the Drosophila single-minded protein that interact with the mouse aryl hydrocarbon receptor nuclear translocator protein.

SIM1 SIM2

3.53e-0556629020169
Pubmed

Zizimin2: a novel, DOCK180-related Cdc42 guanine nucleotide exchange factor expressed predominantly in lymphocytes.

DOCK11 DOCK10

3.53e-05566215710388
Pubmed

The RhoGEF DOCK10 is essential for dendritic spine morphogenesis.

DOCK11 DOCK10

5.29e-05666225851601
Pubmed

Two novel transcripts encoding two Ankyrin repeat containing proteins have preponderant expression during the mouse spermatogenesis.

POTEB2 POTEB

5.29e-05666217171436
Pubmed

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis.

SIM1 SIM2

5.29e-0566628927054
Pubmed

The SAM domains of Anks family proteins are critically involved in modulating the degradation of EphA receptors.

ANKS1B ANKS1A

5.29e-05666220100865
Pubmed

MAGED1 is a novel regulator of a select subset of bHLH PAS transcription factors.

SIM1 SIM2

7.40e-05766227472814
Pubmed

A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development.

RLF BAZ1B

7.40e-05766219099580
Pubmed

POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.

POTEB2 POTEB

9.86e-05866212475935
Pubmed

Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus.

SIM1 SIM2

9.86e-05866214988428
Pubmed

Differential activities of murine single minded 1 (SIM1) and SIM2 on a hypoxic response element. Cross-talk between basic helix-loop-helix/per-Arnt-Sim homology transcription factors.

SIM1 SIM2

9.86e-05866211782478
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

TTC8 DLG5 ANKS1B GPR141 DDX60L HEPHL1 MYO15A ANKS1A

1.51e-0481466823251661
Pubmed

Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants.

SIM1 SIM2

1.58e-041066212024028
Pubmed

Sim1 and Sim2 are required for the correct targeting of mammillary body axons.

SIM1 SIM2

2.31e-041266216291793
Pubmed

The Vertebrate Genome Annotation browser 10 years on.

CDKL3 MOB3C POTEB2 POTEB

2.67e-0416366424316575
Pubmed

Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.

SIM1 SIM2

2.73e-04136628812055
Pubmed

The murine Otp homeobox gene plays an essential role in the specification of neuronal cell lineages in the developing hypothalamus.

SIM1 SIM2

2.73e-041366211071765
Pubmed

Laminar organization of the early developing anterior hypothalamus.

SIM1 SIM2

4.18e-041666216860307
Pubmed

Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease.

ACOT8 PEX1

4.18e-041666214561759
Pubmed

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse.

RLF BAZ1B

5.32e-041866224025402
Pubmed

Biochemistry of mammalian peroxisomes revisited.

ACOT8 ACOX1

6.59e-042066216756494
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DLG5 ATG2B DOCK7 ANKS1A

6.82e-0420966436779422
Pubmed

Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.

DLG5 DOCK11 DOCK7 MOB3C DOCK6

9.76e-0439966537536630
Pubmed

Identification of Peroxisomal Protein Complexes with PTS Receptors, Pex5 and Pex7, in Mammalian Cells.

ACOT8 ACOX1

1.12e-032666230378028
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DLG5 DOCK11 DOCK7 INPP5F DOCK6 SYDE1 ANKS1A

1.22e-0386166736931259
Pubmed

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle.

TECR RNF157

1.30e-032866228655764
Pubmed

Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrix.

ACOT8 ACOX1

1.30e-032866222002062
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

DOCK11 DOCK7 INPP5F DOCK6 ANKS1A

1.59e-0344666524255178
InteractionISM2 interactions

DOCK7 PEX1 DOCK6

1.51e-0516623int:ISM2
InteractionDOCK6 interactions

DOCK11 DOCK7 MOB3C DOCK6

2.29e-0554624int:DOCK6
Cytoband19p13.12

OR10H5 TECR SYDE1

5.30e-055066319p13.12
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEB2 POTEB

4.44e-0413442685
CoexpressionGSE28237_FOLLICULAR_VS_LATE_GC_BCELL_UP

RLF DOCK10 SIM1 DOCK6 LLCFC1 ZFPM2

1.10e-05199666M4886
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TECR PEX1 TMEM143 CUBN RNF157

4.13e-061616655fba13f0aa5002f7eefe219e2c6a07e163f1a50d
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

6.73e-06178665ad3de3e03a401dac64431a541899445262246347
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

8.34e-0618666520340a5b5cc7f07386498a4ef937d6fbc9e347c4
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

8.55e-061876651e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

8.78e-06188665aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel|Adult / Lineage, Cell type, age group and donor

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

9.24e-0619066591bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCellIPF-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

9.24e-06190665ac029e73da5995221c9b9af551d85e4b835e21d6
ToppCellIPF-Endothelial-Lymphatic|IPF / Disease state, Lineage and Cell class

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

9.72e-061926652496edd8f3a41146d418879de9ee2ccc7857431f
ToppCellCOPD-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

9.97e-0619366525bdc557055b5bce6a21f8696b48e991c696b979
ToppCellControl-Endothelial-Lymphatic|Control / Disease state, Lineage and Cell class

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

9.97e-0619366564d19be73e5432d491436a01da5de5c926b615a9
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.02e-05194665f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCellnucseq-Endothelial-Endothelial_Lymphatic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.02e-051946655d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCellnucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.02e-051946653b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.13e-051986659ab0db78394e730f6866b2db80047149024ad5f6
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.13e-05198665b3a020522e064bb61949d38e442f24026e339364
ToppCellBronchial-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.13e-05198665fc4b7c3ad52bc5c8b40fa04a156bfbb58afa2872
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G DOCK6 ZFPM2

1.13e-05198665e47d0e2c6353315c85d7007742bb16b0f05795ed
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ANKS1B SIM1 HEPHL1 NEB

9.81e-05162664bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PIEZO2 GPR182 PARD6G NEB

1.10e-041676646a03d16165e0b003092c39972928981abd4a75aa
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

PIEZO2 PARD6G DOCK6 ZFPM2

1.26e-04173664dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Lymphatic_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

PIEZO2 GPR182 PARD6G SYDE1

1.29e-04174664d551bc29afef071adf4c9bb80345352ec33441d8
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 GPR182 PARD6G LBP

1.32e-04175664f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 GPR182 PARD6G ZFPM2

1.38e-04177664c274fbdc141855ff4581d437d4997c64cc193278
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PIEZO2 GPR182 PARD6G ZFPM2

1.38e-04177664326fde0734ef0d7272693966d346ca479b9d8147
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 GPR182 PARD6G ZFPM2

1.38e-04177664c8a51e480b978dc0ded85583261f2c892e085be8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PIEZO2 GPR182 PARD6G ZFPM2

1.38e-04177664f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D231|Adult / Lineage, Cell type, age group and donor

PIEZO2 GPR182 PARD6G ZFPM2

1.41e-04178664c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCellILEUM-non-inflamed-(7)_Lymphatics|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PIEZO2 GPR182 PARD6G ANKS1A

1.44e-0417966499777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 GPR182 PARD6G DOCK6

1.50e-04181664e898ecb8d8f2eb2204225b7b0d665cadcd241139
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-NK-NK-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SYTL3 GPR141 IPP ZNF445

1.50e-04181664a7f0a83e4f48eca8e753bda13c744cf41359fcc0
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

1.50e-04181664cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PIEZO2 GPR182 DOCK6 ZFPM2

1.57e-041836644d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 GPR182 PARD6G ZFPM2

1.63e-041856649de1db2ce9e44956b1214daf6e1e161334679c88
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CCNG2 ZNF14 DOCK7 PEX1

1.63e-041856644a5e70ac41e5f3b25a773304ffef3c2a3dd5549d
ToppCell3'-Child09-12-SmallIntestine-Endothelial-lymphatic_endothelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 GPR182 PARD6G ZFPM2

1.63e-0418566418f5d9438c76e37988a7d17aa2a080af6bedbfc4
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PIEZO2 PARD6G DOCK6 ZFPM2

1.63e-0418566436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

PIEZO2 PARD6G DOCK6 ZFPM2

1.63e-041856644a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellEndothelial-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

TTC8 PIEZO2 PARD6G DOCK6

1.74e-04188664ecb74d67314a43b5805b7f2a7bb9ff6c5a60200a
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

1.74e-0418866454550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCellEndothelial-endothelial_cell_of_lymph_vessel|World / Lineage, Cell type, age group and donor

GPR182 PARD6G DOCK6 ZFPM2

1.74e-0418866480910dcbb51990f2baed240f319456c0d3fa2065
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIEZO2 GPR182 PARD6G ZFPM2

1.74e-041886642db80767903703e7e0a1a37c598f7877a909ee94
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

1.74e-04188664a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIEZO2 PARD6G DOCK6 ZFPM2

1.74e-04188664c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYTL3 TECR DOCK10 RNF157

1.77e-041896649ab77c6fcb573854da5922412f53d2168bda6b58
ToppCellCOVID-19-lung-Lymphatic_EC|lung / Disease (COVID-19 only), tissue and cell type

PIEZO2 GPR182 PARD6G ZFPM2

1.77e-04189664c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

1.77e-041896641137583e21d874c201c20581ba1995e2bfa3de59
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Lymphatic|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

PIEZO2 GPR182 PARD6G DOCK6

1.81e-041906648d6ec2fc0af19a5cb16fff34f8b131b71b33d45f
ToppCelldroplet-Heart-nan-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

1.81e-041906647068754c29f63a331e2b6c54715f3b26f37ad32b
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PIEZO2 PARD6G DOCK6 ZFPM2

1.81e-041906646e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PIEZO2 GPR182 PARD6G ANKS1A

1.81e-041906649ce301841ce9486701fa28eb2a9929e35d476878
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CENPL ATG2B PEX1 ZNF850

1.81e-041906643f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCellControl-Endothelial-Lymphatic|World / Disease state, Lineage and Cell class

GPR182 PARD6G DOCK6 ZFPM2

1.88e-04192664f95fb188aa642f3d0618242a770e7c4b70544adb
ToppCellCOVID-19-lung-Lymphatic_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PIEZO2 GPR182 PARD6G ZFPM2

1.88e-04192664cbe57cda44232b183821ac633b60a2668265e616
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPL ATG2B PEX1 ZNF850

1.88e-04192664c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellCOPD-Endothelial-Lymphatic|COPD / Disease state, Lineage and Cell class

PIEZO2 GPR182 DOCK6 ZFPM2

1.92e-0419366418bcf08068a236c4575c7a07181ac893dfdcbeeb
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

1.96e-04194664c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 GPR182 PARD6G LBP

1.96e-04194664937ee85ffd50869b60f0f6e91017ab77e8b24c0b
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR182 PARD6G LBP DOCK6

2.00e-04195664df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PIEZO2 ANKS1B DOCK10 LRRTM3

2.00e-041956640e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF607 LRRTM3 NEB RNF157

2.04e-04196664ce13af36fc2932e8125013041742593ff3d07e86
ToppCellBronchial-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF607 LRRTM3 NEB RNF157

2.04e-0419666496e5c6d155273e82ebafa180df8bb589c3e3e54e
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 GPR182 PARD6G ANKS1A

2.12e-041986645d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCellmedial-Endothelial-Lymphatic-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 GPR182 PARD6G LBP

2.12e-0419866441983d405215b974044e2e9e6c212b134336a6fe
ToppCellmedial-2-Endothelial-Lymphatic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 GPR182 PARD6G LBP

2.12e-04198664e4274584512a72270087a1ab104fab449a2f83bc
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G DOCK6

2.12e-04198664306e28d31fd587409a12dcccc6b2abd7dc9c2e0a
ToppCell5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PIEZO2 GPR182 PARD6G ANKS1A

2.12e-0419866499d6a64f3410dae3019161feef20a8f06081a24b
ToppCellmedial-Endothelial-Lymphatic|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PIEZO2 GPR182 PARD6G LBP

2.12e-041986641760fede363544bc0fa2e22fe36aff522abd2525
ToppCellTracheal-10x5prime-Endothelial-Endothelia_lymphatic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G DOCK6

2.12e-0419866405429f18e1d74880c1835568c86177f661b3477a
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF14 SYTL3 CDIN1 CLK4

2.16e-0419966426bb93347e6722abd174dfa62cab692ce2b7eb23
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_activated|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

DZIP1L DOCK10 INPP5F NEB

2.16e-041996643b2bd3caf4d189a1726a737b0121860b265eec04
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G ANKS1A

2.20e-0420066476e90231aa94afc12e618da8ae314c51644acab4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

PIEZO2 ARSL SIM1 SIM2

2.20e-0420066407d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial|10w / Sample Type, Dataset, Time_group, and Cell type.

PIEZO2 ARSL SIM1 SIM2

2.20e-04200664ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PIEZO2 GPR182 PARD6G ANKS1A

2.20e-04200664e3e80cb16e0d2e24efc16b62316a6da91bf81ea5
ToppCell(05)_Ciliated-(1)_24hpi|(05)_Ciliated / shred by cell type and Timepoint

OVGP1 MSH3 ZFPM2

3.03e-048866376959e7e3f6fae07c9881a29c28ba847be406694
DrugEicosanoyl coenzyme A

ACOT8 ACOX1 TECR

3.60e-0611653CID000439636
Diseaselevel of Phosphatidylinositol (18:1_18:1) in blood serum

DOCK7 DOCK6

2.92e-0413582OBA_2045159
Diseaseresponse to olanzapine

ANKS1B ZFPM2

3.92e-0415582GO_0097333
Diseasestem Cell Growth Factor beta measurement

PIEZO2 TTC41P ANKS1B

4.40e-0475583EFO_0008292
Diseaselevel of Phosphatidylinositol (18:0_18:1) in blood serum

DOCK7 DOCK6

5.69e-0418582OBA_2045155
Diseaselevel of Phosphatidylinositol (18:0_18:2) in blood serum

DOCK7 DOCK6

7.78e-0421582OBA_2045156
Diseasecholesteryl ester measurement, intermediate density lipoprotein measurement

N4BP2L1 DOCK7 BAZ1B

8.51e-0494583EFO_0008595, EFO_0010351
Diseaselipid measurement, intermediate density lipoprotein measurement

N4BP2L1 DOCK7 BAZ1B

9.04e-0496583EFO_0004529, EFO_0008595
Diseaselevel of Phosphatidylinositol (18:0_20:4) in blood serum

DOCK7 DOCK6

9.36e-0423582OBA_2045158
Diseaseperiodontitis

RGMA GPR141 LBP ZFPM2

9.79e-04223584EFO_0000649
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

N4BP2L1 DOCK7 SIM1

9.89e-0499583EFO_0004611, EFO_0007878
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

N4BP2L1 DOCK7 SIM1

1.08e-03102583EFO_0004329, EFO_0004611
Diseasecholesterol to total lipids in very large HDL percentage

DOCK7 DOCK6

1.70e-0331582EFO_0022243
Diseaseapolipoprotein B measurement

ZNF14 N4BP2L1 DOCK7 BAZ1B SIM1 DOCK6

1.89e-03663586EFO_0004615

Protein segments in the cluster

PeptideGeneStartEntry
VSEDVHVHSLHCYFV

ACOT8

71

O14734
HLLALCDYFHHTFIR

C8orf74

106

Q6P047
QHSDHEFLMHYCERF

ARSL

446

P51690
KHAICAAEFYVTHEI

CXorf58

66

Q96LI9
CHFLESHYLHEQVKT

FTHL17

131

Q9BXU8
DSIDYRFNHHCKDHT

BAZ1B

931

Q9UIG0
IYCYHHDEAHSILES

ARHGEF38

186

Q9NXL2
FIDHTVLDELQHYCH

CDKL3

81

Q8IVW4
FLHLYHTIILCHTSE

CCNG2

161

Q16589
TKDLQTSHHYCHVFS

ANKS1A

1026

Q92625
HYICLHSSSFSLYHK

ATG2B

1106

Q96BY7
CHDLLEFSENYIHVH

IPP

151

Q9Y573
GIHEEYNEEHCFKFH

GPR141

156

Q7Z602
SHHHVICELLSDYKE

POTEB2

311

H3BUK9
KDLKSNHHYCHVFTA

ANKS1B

1151

Q7Z6G8
GTHSYHTCHLCDKTF

DZIP1L

161

Q8IYY4
EHYHSLCKAVHHLAT

MSH3

816

P20585
SAIFHLAFCGHKEIH

OR10H5

161

Q8NGA6
YEFHSLNIHSCELLH

LBP

76

P18428
TDHTFLQKCHYHHGA

MYO15A

1671

Q9UKN7
THKKFYCSSHAAEHV

ZFPM2

1136

Q8WW38
CSVKHDDVYFDHFHP

DDX60L

971

Q5H9U9
DVLFYHFLHHVTDLK

EFCAB9

46

A8MZ26
CEEVAKETDFYHTLH

DLG5

216

Q8TDM6
KFEDFYKLVVHTHHI

PARD6G

41

Q9BYG4
DHFVAVCHPLHYTAK

OR1F1

121

O43749
HLMFETFHLEFHYNC

CUBN

971

O60494
SAFELEFKDFHLEHH

CUBN

1201

O60494
ASEAHCHYVVVKLFS

ACOX1

526

Q15067
EKHHILFSFYHVTCD

DOCK10

756

Q96BY6
HHLLFTFYHVSCEIN

DOCK11

726

Q5JSL3
IYTQDLHVHKFFHHC

DOCK11

821

Q5JSL3
CVTENHHLLFTFYHV

DOCK6

626

Q96HP0
TDHHHLLFTFYHVSC

DOCK7

641

Q96N67
DLFMDCLYSHFHRHF

CENPL

281

Q8N0S6
CLYSHFHRHFKIHLS

CENPL

286

Q8N0S6
KASFGDECSHHAYLH

CDIN1

216

Q9Y2V0
EEEHITKIYHCSRTH

DDX12P

241

Q92771
DECHHTHKDTVYNVI

DHX58

131

Q96C10
DIHTIHYHAESFLFK

HEPHL1

1001

Q6MZM0
AAVHKHSFHLSFCFS

LLCFC1

81

Q96L11
HHQFKESDCHYLEAR

CLK4

46

Q9HAZ1
SHLTYVSFDFHEHCR

INPP5F

401

Q9Y2H2
SATSVFHKHCAIHVF

PEX1

301

O43933
VFVHVYIHHFDSILS

MOB3C

161

Q70IA8
SAIFHLAFCGHKEIH

OR10H1

161

Q9Y4A9
HHDGAAHKLVCYFTN

OVGP1

16

Q12889
HHKAFSTCAAHLAVF

OR6K6

261

Q8NGW6
ASAVDFKHHIEVLHY

SYDE1

581

Q6ZW31
EFAIHYCFKTHSLEI

SYTL3

311

Q4VX76
YFGHCHVLLGTFEKH

RNF157

211

Q96PX1
SYCGVHHELLSHKSF

LRRTM3

531

Q86VH5
SHHHVICELLSDYKE

POTEB

311

A0A0A6YYL3
HCHLVHLLYFFYDVI

GPR182

291

O15218
IEKTLYHHVHGCDVF

SIM2

261

Q14190
IEKTLYHHVHGCDTF

SIM1

261

P81133
SPEICHYEKSFHKHS

RGMA

141

Q96B86
FEYIFHHENDVKTIH

TTC8

196

Q8TAM2
HVDFCTLFHYHQILA

TMEM143

106

Q96AN5
SHEYVTFSKLEDCHL

RLF

651

Q13129
FHCASYLVRHESVHA

ZNF607

626

Q96SK3
SFLLVCILHLHYFHD

PIEZO2

796

Q9H5I5
HSFERFYHEEFTEKC

TTC41P

266

Q6P2S7
VVHLACICHSFHYIK

TECR

126

Q9NZ01
FHCKSYVLEHQRIHT

ZNF445

606

P59923
ECGKAFHHFSYLVKH

ZNF850

201

A8MQ14
VGKTFSYHHCFRKHE

ZNF14

146

P17017
YEHDVTFHSVLHAEK

N4BP2L1

176

Q5TBK1
RHISTVKYHEDFEKH

NEB

6431

P20929