Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3K36 trimethyltransferase activity

NSD2 ASH1L

3.33e-055372GO:0140955
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA3 PLXNA1

2.18e-0412372GO:0017154
GeneOntologyMolecularFunctionhistone H3K36 methyltransferase activity

NSD2 ASH1L

2.57e-0413372GO:0046975
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN4X NLGN4Y

3.94e-0416372GO:0042043
GeneOntologyMolecularFunctionchloride ion binding

NLGN4X NLGN4Y

3.94e-0416372GO:0031404
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

3.31e-062382GO:0021628
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

9.90e-063382GO:0021627
GeneOntologyBiologicalProcessterritorial aggressive behavior

NLGN4X NLGN4Y

9.90e-063382GO:0002124
GeneOntologyBiologicalProcessmale courtship behavior

NLGN4X NLGN4Y

1.98e-054382GO:0008049
GeneOntologyBiologicalProcessuterus development

GREB1L MYOCD ASH1L

2.26e-0530383GO:0060065
GeneOntologyBiologicalProcesscardiac chamber development

GREB1L MYOCD TEK NSD2 PRDM1

4.17e-05212385GO:0003205
GeneOntologyBiologicalProcessmiRNA metabolic process

MYOCD MRTFB AGO1 MRTFA

6.68e-05119384GO:0010586
GeneOntologyBiologicalProcessgonadotrophin-releasing hormone neuronal migration to the hypothalamus

PLXNA3 PLXNA1

6.90e-057382GO:0021828
GeneOntologyBiologicalProcesshypothalamic tangential migration using cell-axon interactions

PLXNA3 PLXNA1

6.90e-057382GO:0021856
GeneOntologyBiologicalProcesscourtship behavior

NLGN4X NLGN4Y

6.90e-057382GO:0007619
GeneOntologyBiologicalProcessbrainstem development

NLGN4X NLGN4Y

9.19e-058382GO:0003360
GeneOntologyBiologicalProcessolfactory nerve development

PLXNA3 PLXNA1

9.19e-058382GO:0021553
GeneOntologyBiologicalProcesshypothalamus cell migration

PLXNA3 PLXNA1

1.18e-049382GO:0021855
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron differentiation

PLXNA3 PLXNA1

1.18e-049382GO:0021886
GeneOntologyBiologicalProcesshypothalamus gonadotrophin-releasing hormone neuron development

PLXNA3 PLXNA1

1.18e-049382GO:0021888
GeneOntologyBiologicalProcesspresynaptic membrane assembly

NLGN4X NLGN4Y

1.47e-0410382GO:0097105
GeneOntologyBiologicalProcesscranial nerve formation

PLXNA3 PLXNA1

1.80e-0411382GO:0021603
GeneOntologyBiologicalProcesspostsynaptic membrane assembly

NLGN4X NLGN4Y

1.80e-0411382GO:0097104
GeneOntologyBiologicalProcesspositive regulation of miRNA transcription

MYOCD MRTFB MRTFA

1.93e-0461383GO:1902895
GeneOntologyBiologicalProcesscardiac ventricle development

GREB1L MYOCD NSD2 PRDM1

2.15e-04161384GO:0003231
GeneOntologyBiologicalProcessaggressive behavior

NLGN4X NLGN4Y

2.55e-0413382GO:0002118
GeneOntologyBiologicalProcesspresynaptic membrane organization

NLGN4X NLGN4Y

2.55e-0413382GO:0097090
GeneOntologyBiologicalProcesscentral nervous system development

SOX6 PLXNA3 ZIC4 MRTFB NLGN4X RNF103 NLGN4Y PLXNA1 MRTFA

2.56e-041197389GO:0007417
GeneOntologyBiologicalProcesshypothalamus cell differentiation

PLXNA3 PLXNA1

2.97e-0414382GO:0021979
GeneOntologyBiologicalProcesspositive regulation of miRNA metabolic process

MYOCD MRTFB MRTFA

3.28e-0473383GO:2000630
GeneOntologyBiologicalProcessmale mating behavior

NLGN4X NLGN4Y

3.42e-0415382GO:0060179
GeneOntologyBiologicalProcessneuron cell-cell adhesion

NLGN4X NLGN4Y

3.90e-0416382GO:0007158
GeneOntologyBiologicalProcessanimal organ morphogenesis

GREB1L SOX6 MUC19 MRTFB TEK NSD2 PLXNA1 ASH1L PRDM1

3.94e-041269389GO:0009887
GeneOntologyBiologicalProcessheart development

GREB1L SOX6 MYOCD MRTFB TEK NSD2 PRDM1

4.07e-04757387GO:0007507
GeneOntologyBiologicalProcessregulation of miRNA transcription

MYOCD MRTFB MRTFA

4.79e-0483383GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

MYOCD MRTFB MRTFA

4.96e-0484383GO:0061614
GeneOntologyBiologicalProcessneuron migration

PLXNA3 MRTFB PLXNA1 MRTFA

6.76e-04218384GO:0001764
GeneOntologyBiologicalProcesssynaptic vesicle endocytosis

NLGN4X NLGN4Y STON2

7.32e-0496383GO:0048488
GeneOntologyBiologicalProcesssmooth muscle cell differentiation

MYOCD MRTFB MRTFA

8.01e-0499383GO:0051145
GeneOntologyBiologicalProcessbrain development

SOX6 PLXNA3 MRTFB NLGN4X NLGN4Y PLXNA1 MRTFA

8.64e-04859387GO:0007420
GeneOntologyBiologicalProcesspresynaptic endocytosis

NLGN4X NLGN4Y STON2

8.73e-04102383GO:0140238
GeneOntologyBiologicalProcessvocalization behavior

NLGN4X NLGN4Y

8.89e-0424382GO:0071625
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

MYOCD MRTFB MRTFA

8.99e-04103383GO:2000628
GeneOntologyBiologicalProcessregulation of cardiac muscle cell differentiation

SOX6 MYOCD

9.65e-0425382GO:2000725
GeneOntologyBiologicalProcesscirculatory system development

GREB1L SOX6 MYOCD MRTFB GPNMB AGO1 TEK NSD2 PRDM1

9.95e-041442389GO:0072359
GeneOntologyBiologicalProcesssynaptic vesicle recycling

NLGN4X NLGN4Y STON2

1.12e-03111383GO:0036465
GeneOntologyBiologicalProcessdevelopmental growth

PLXNA3 MYOCD NLGN4X RAPH1 NLGN4Y PLXNA1 RAI1

1.22e-03911387GO:0048589
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

GREB1L TEK PLXNA1 PRDM1

1.26e-03258384GO:0001763
GeneOntologyBiologicalProcesshead development

SOX6 PLXNA3 MRTFB NLGN4X NLGN4Y PLXNA1 MRTFA

1.28e-03919387GO:0060322
GeneOntologyBiologicalProcessforebrain neuron development

PLXNA3 PLXNA1

1.39e-0330382GO:0021884
GeneOntologyBiologicalProcesshypothalamus development

PLXNA3 PLXNA1

1.49e-0331382GO:0021854
GeneOntologyBiologicalProcessgrowth

PLXNA3 MYOCD NLGN4X OSGIN2 RAPH1 NLGN4Y PLXNA1 RAI1

1.58e-031235388GO:0040007
GeneOntologyBiologicalProcesscranial nerve morphogenesis

PLXNA3 PLXNA1

1.58e-0332382GO:0021602
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN4X NLGN4Y

2.03e-054392GO:0098983
GeneOntologyCellularComponentsymmetric synapse

NLGN4X NLGN4Y

2.61e-0413392GO:0032280
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA3 PLXNA1

2.61e-0413392GO:0002116
GeneOntologyCellularComponentglycinergic synapse

NLGN4X NLGN4Y

6.31e-0420392GO:0098690
GeneOntologyCellularComponentasymmetric, glutamatergic, excitatory synapse

NLGN4X NLGN4Y

9.12e-0424392GO:0098985
GeneOntologyCellularComponentinhibitory synapse

NLGN4X NLGN4Y

1.52e-0331392GO:0060077
MousePhenoabnormal uterus physiology

GREB1 ASH1L PRDM1

4.24e-0530323MP:0009671
MousePhenoabnormal postimplantation uterine environment

GREB1 ASH1L

1.06e-047322MP:0009669
DomainRPEL_repeat

MYOCD MRTFB MRTFA

2.70e-077383IPR004018
DomainRPEL

MYOCD MRTFB MRTFA

2.70e-077383PS51073
DomainRPEL

MYOCD MRTFB MRTFA

2.70e-077383PF02755
DomainRPEL

MYOCD MRTFB MRTFA

2.70e-077383SM00707
DomainGREB1

GREB1L GREB1

4.03e-062382PF15782
DomainGREB1

GREB1L GREB1

4.03e-062382IPR028422
DomainNLGN4

NLGN4X NLGN4Y

4.03e-062382IPR030025
Domain-

MYOCD MRTFB MRTFA

1.01e-05213831.10.720.30
DomainSAP

MYOCD MRTFB MRTFA

1.17e-0522383PF02037
DomainSAP

MYOCD MRTFB MRTFA

1.34e-0523383SM00513
DomainSAP

MYOCD MRTFB MRTFA

1.73e-0525383PS50800
DomainSAP_dom

MYOCD MRTFB MRTFA

1.73e-0525383IPR003034
DomainPHD

SHPRH NSD2 RAI1 ASH1L

3.14e-0589384SM00249
DomainZnf_PHD

SHPRH NSD2 RAI1 ASH1L

3.43e-0591384IPR001965
DomainAWS

NSD2 ASH1L

4.02e-055382PS51215
DomainNlgn

NLGN4X NLGN4Y

4.02e-055382IPR000460
DomainAWS_dom

NSD2 ASH1L

4.02e-055382IPR006560
DomainAWS

NSD2 ASH1L

4.02e-055382SM00570
DomainZF_PHD_2

SHPRH NSD2 RAI1 ASH1L

4.06e-0595384PS50016
DomainZF_PHD_1

SHPRH NSD2 RAI1 ASH1L

4.23e-0596384PS01359
DomainSET

NSD2 ASH1L PRDM1

7.85e-0541383PF00856
DomainSET

NSD2 ASH1L PRDM1

1.11e-0446383SM00317
DomainSET_dom

NSD2 ASH1L PRDM1

1.43e-0450383IPR001214
DomainSET

NSD2 ASH1L PRDM1

1.43e-0450383PS50280
DomainPlexin_cytopl

PLXNA3 PLXNA1

1.44e-049382PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA1

1.44e-049382IPR013548
DomainPlexin

PLXNA3 PLXNA1

1.44e-049382IPR031148
DomainCarboxylesterase_B_CS

NLGN4X NLGN4Y

3.10e-0413382IPR019819
DomainZinc_finger_PHD-type_CS

SHPRH NSD2 ASH1L

3.11e-0465383IPR019786
DomainCOesterase

NLGN4X NLGN4Y

3.61e-0414382PF00135
DomainCARBOXYLESTERASE_B_2

NLGN4X NLGN4Y

3.61e-0414382PS00941
DomainCarbesteraseB

NLGN4X NLGN4Y

3.61e-0414382IPR002018
DomainPost-SET_dom

NSD2 ASH1L

4.75e-0416382IPR003616
DomainPostSET

NSD2 ASH1L

4.75e-0416382SM00508
DomainPOST_SET

NSD2 ASH1L

4.75e-0416382PS50868
DomainIPT

PLXNA3 PLXNA1

1.37e-0327382SM00429
DomainTIG

PLXNA3 PLXNA1

1.81e-0331382PF01833
DomainSEMA

PLXNA3 PLXNA1

1.81e-0331382PS51004
DomainSema

PLXNA3 PLXNA1

1.81e-0331382SM00630
DomainSemap_dom

PLXNA3 PLXNA1

1.81e-0331382IPR001627
DomainSema

PLXNA3 PLXNA1

1.81e-0331382PF01403
DomainPlexin_repeat

PLXNA3 PLXNA1

1.92e-0332382IPR002165
DomainPSI

PLXNA3 PLXNA1

1.92e-0332382PF01437
DomainIPT

PLXNA3 PLXNA1

1.92e-0332382IPR002909
DomainZnf_FYVE_PHD

SHPRH NSD2 ASH1L

3.29e-03147383IPR011011
DomainPSI

PLXNA3 PLXNA1

3.61e-0344382IPR016201
DomainPSI

PLXNA3 PLXNA1

3.94e-0346382SM00423
DomainHMG_box

SOX6 NSD2

5.20e-0353382PF00505
DomainHMG_BOX_2

SOX6 NSD2

5.40e-0354382PS50118
DomainHMG

SOX6 NSD2

5.40e-0354382SM00398
Domain-

SOX6 NSD2

5.59e-03553821.10.30.10
DomainHMG_box_dom

SOX6 NSD2

7.73e-0365382IPR009071
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA1

1.67e-049312MM15030
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA1

4.19e-0414312M7578
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA1

4.19e-0414312MM15029
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA1

4.83e-0415312MM15031
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA1

5.51e-0416312M8245
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA1

5.51e-0416312M16498
Pubmed

Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation.

MYOCD MRTFB MRTFA

1.30e-09339317363709
Pubmed

Myocardin-related transcription factor contributes to renal fibrosis through the regulation of extracellular microenvironment surrounding fibroblasts.

MYOCD MRTFB MRTFA

1.30e-09339337289107
Pubmed

The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression.

MYOCD MRTFB MRTFA

5.21e-09439317991879
Pubmed

Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

MYOCD MRTFB MRTFA

5.21e-09439312397177
Pubmed

Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation.

MYOCD MRTFB MRTFA

5.21e-09439316204380
Pubmed

Thymine DNA glycosylase represses myocardin-induced smooth muscle cell differentiation by competing with serum response factor for myocardin binding.

MYOCD MRTFB MRTFA

1.30e-08539318945672
Pubmed

Muscle-specific signaling mechanism that links actin dynamics to serum response factor.

MYOCD MRTFB MRTFA

1.30e-08539315798203
Pubmed

Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation.

MYOCD MRTFB MRTFA

1.30e-08539317360478
Pubmed

Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.

MYOCD MRTFB MRTFA

3.70e-071339329114040
Pubmed

Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells.

MRTFB MRTFA

1.23e-06239228623279
Pubmed

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

NLGN4X NLGN4Y

1.23e-06239229106499
Pubmed

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

NLGN4X NLGN4Y

1.23e-06239226456829
Pubmed

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.

NLGN4X NLGN4Y

1.23e-06239224104404
Pubmed

MRTF-A/B suppress the oncogenic properties of v-ras- and v-src-mediated transformants.

MRTFB MRTFA

1.23e-06239220338973
Pubmed

Depletion of the transcriptional coactivators megakaryoblastic leukaemia 1 and 2 abolishes hepatocellular carcinoma xenograft growth by inducing oncogene-induced senescence.

MRTFB MRTFA

1.23e-06239223853104
Pubmed

Synaptic localisation of SRF coactivators, MKL1 and MKL2, and their role in dendritic spine morphology.

MRTFB MRTFA

1.23e-06239229335431
Pubmed

Exome-wide Association Study Identifies GREB1L Mutations in Congenital Kidney Malformations.

GREB1L GREB1

1.23e-06239229100090
Pubmed

Myocardin and myocardin-related transcription factor-A synergistically mediate actin cytoskeletal-dependent inhibition of liver fibrogenesis.

MYOCD MRTFA

1.23e-06239231928221
Pubmed

The MRTF-A/B function as oncogenes in pancreatic cancer.

MRTFB MRTFA

1.23e-06239226498848
Pubmed

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

NLGN4X NLGN4Y

1.23e-06239232243781
Pubmed

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes.

MRTFB MRTFA

1.23e-06239212944485
Pubmed

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

NLGN4X NLGN4Y

1.23e-06239222989184
Pubmed

Unusually rapid evolution of Neuroligin-4 in mice.

NLGN4X NLGN4Y

1.23e-06239218434543
Pubmed

Myocardin-related transcription factors are required for skeletal muscle development.

MRTFB MRTFA

1.23e-06239227385017
Pubmed

Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells.

MYOCD MRTFA

1.23e-06239214970199
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4X NLGN4Y

1.23e-06239223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4X NLGN4Y

1.23e-06239224855039
Pubmed

Myocardin-related transcription factors are required for cardiac development and function.

MRTFB MRTFA

1.23e-06239226386146
Pubmed

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.

NLGN4X NLGN4Y

1.23e-06239237001827
Pubmed

Reorganization of the actin cytoskeleton via transcriptional regulation of cytoskeletal/focal adhesion genes by myocardin-related transcription factors (MRTFs/MAL/MKLs).

MRTFB MRTFA

1.23e-06239217714703
Pubmed

A Gene Implicated in Activation of Retinoic Acid Receptor Targets Is a Novel Renal Agenesis Gene in Humans.

GREB1L GREB1

1.23e-06239228739660
Pubmed

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.

NLGN4X NLGN4Y

1.23e-06239237080762
Pubmed

Myocardin related transcription factors are required for coordinated cell cycle progression.

MRTFB MRTFA

1.23e-06239223656782
Pubmed

Myocardin regulates BMP10 expression and is required for heart development.

MYOCD MRTFB MRTFA

1.47e-062039322996691
Pubmed

Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels.

MRTFB TEK MRTFA

1.98e-062239325516967
Pubmed

Hemodynamic force is required for vascular smooth muscle cell recruitment to blood vessels during mouse embryonic development.

MYOCD MRTFB MRTFA

2.60e-062439330796970
Pubmed

Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression.

MYOCD MRTFB MRTFA

2.95e-062539320019329
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN4X NLGN4Y

3.67e-06339218628683
Pubmed

The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.

MRTFB MRTFA

3.67e-06339222139079
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1

3.67e-0633928806646
Pubmed

Role of CRP2-MRTF interaction in functions of myofibroblasts.

MRTFB MRTFA

3.67e-06339237164693
Pubmed

A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells.

MRTFB MRTFA

3.67e-06339226024305
Pubmed

MKL1 and MKL2 play redundant and crucial roles in megakaryocyte maturation and platelet formation.

MRTFB MRTFA

3.67e-06339222806889
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN4X NLGN4Y

3.67e-06339232011705
Pubmed

Endothelial depletion of murine SRF/MRTF provokes intracerebral hemorrhagic stroke.

MRTFB MRTFA

3.67e-06339226221020
Pubmed

RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding.

MYOCD MRTFA

3.67e-06339218025109
Pubmed

Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice.

MYOCD MRTFA

3.67e-06339223103763
Pubmed

Myocardin-related transcription factors and SRF are required for cytoskeletal dynamics and experimental metastasis.

MRTFB MRTFA

3.67e-06339219198601
Pubmed

Megakaryoblastic leukemia-1/2, a transcriptional co-activator of serum response factor, is required for skeletal myogenic differentiation.

MRTFB MRTFA

3.67e-06339214565952
Pubmed

Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor.

MYOCD MRTFA

3.67e-06339211439182
Pubmed

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

NLGN4X NLGN4Y

3.67e-06339221282647
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1

3.67e-06339211241833
Pubmed

Myeloid translocation gene 16b is a dual A-kinase anchoring protein that interacts selectively with plexins in a phospho-regulated manner.

PLXNA3 PLXNA1

3.67e-06339220138877
Pubmed

Mechanosensitive Gene Regulation by Myocardin-Related Transcription Factors Is Required for Cardiomyocyte Integrity in Load-Induced Ventricular Hypertrophy.

MRTFB MRTFA

3.67e-06339229716942
Pubmed

Control of phenotypic plasticity of smooth muscle cells by bone morphogenetic protein signaling through the myocardin-related transcription factors.

MRTFB MRTFA

3.67e-06339217947237
Pubmed

Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling.

MRTFB MRTFA

3.67e-06339218056415
Pubmed

Recapitulating early development of mouse musculoskeletal precursors of the paraxial mesoderm in vitro.

GREB1L MYOCD GREB1

5.18e-063039329555813
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN4X NLGN4Y

7.34e-06439216077734
Pubmed

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.

NLGN4X NLGN4Y

7.34e-06439217292328
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN4X NLGN4Y

7.34e-06439212669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN4X NLGN4Y

7.34e-06439222671294
Pubmed

MKL1/2 and ELK4 co-regulate distinct serum response factor (SRF) transcription programs in macrophages.

MRTFB MRTFA

7.34e-06439224758171
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN4X NLGN4Y

7.34e-06439220579107
Pubmed

Determination of cell adhesion sites of neuropilin-1.

PLXNA3 PLXNA1

7.34e-06439210725340
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA1

7.34e-06439211306810
Pubmed

BRG1 (Brahma-Related Gene 1) Promotes Endothelial Mrtf Transcription to Establish Embryonic Capillary Integrity.

MRTFB MRTFA

7.34e-06439228729363
Pubmed

Nuclear RhoA signaling regulates MRTF-dependent SMC-specific transcription.

MRTFB MRTFA

7.34e-06439224906914
Pubmed

Oxidative Stress Enhances the TGF-β2-RhoA-MRTF-A/B Axis in Cells Entering Endothelial-Mesenchymal Transition.

MRTFB MRTFA

7.34e-06439235216178
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA1

7.34e-06439225518740
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA3 PLXNA1

7.34e-0643928570614
Pubmed

Loss of Rearranged L-Myc Fusion (RLF) results in defects in heart development in the mouse.

RLF MRTFB MRTFA

1.07e-053839327930960
Pubmed

Neuroligins and neurexins link synaptic function to cognitive disease.

NLGN4X NLGN4Y

1.22e-05539218923512
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN4X NLGN4Y

1.22e-05539210996085
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

PLXNA3 PLXNA1

1.22e-05539225313870
Pubmed

Differential regulation of hair cell actin cytoskeleton mediated by SRF and MRTFB.

MRTFB MRTFA

1.22e-05539237982489
Pubmed

MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation.

MRTFB MRTFA

1.22e-05539223764775
Pubmed

Systematic perturbations of SETD2, NSD1, NSD2, NSD3, and ASH1L reveal their distinct contributions to H3K36 methylation.

NSD2 ASH1L

1.22e-05539239390582
Pubmed

Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling.

MRTFB MRTFA

1.22e-05539233361330
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN4X NLGN4Y

1.22e-05539237865312
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN4X NLGN4Y

1.83e-05639221838267
Pubmed

Mutations in GREB1L Cause Bilateral Kidney Agenesis in Humans and Mice.

GREB1L GREB1

1.83e-05639229100091
Pubmed

Endothelial SRF/MRTF ablation causes vascular disease phenotypes in murine retinae.

MRTFB MRTFA

1.83e-05639223563308
Pubmed

MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development.

MRTFB MRTFA

1.83e-05639225573994
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN4X NLGN4Y

1.83e-05639229724786
Pubmed

Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression.

MRTFB MRTFA

1.83e-05639217183527
Pubmed

Histone H2A ubiquitination inhibits the enzymatic activity of H3 lysine 36 methyltransferases.

NSD2 ASH1L

1.83e-05639224019522
Pubmed

Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.

PLXNA3 PLXNA1

1.83e-05639219480842
Pubmed

Temporal control of PDGFRα regulates the fibroblast-to-myofibroblast transition in wound healing.

MRTFB MRTFA

2.56e-05739235977484
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA3 PLXNA1

2.56e-05739219063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA3 PLXNA1

2.56e-05739219655386
Pubmed

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

PLXNA3 PLXNA1

2.56e-05739210520994
Pubmed

The actin-binding protein CAP1 represses MRTF-SRF-dependent gene expression in mouse cerebral cortex.

MRTFB MRTFA

2.56e-05739238713765
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNA1

3.42e-05839215661641
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NLGN4X NLGN4Y

3.42e-05839230871858
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA3 PLXNA1

3.42e-05839222368082
Pubmed

PlexinA2 and semaphorin signaling during cardiac neural crest development.

PLXNA3 PLXNA1

4.39e-05939211688557
Pubmed

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.

NLGN4X NLGN4Y

4.39e-05939223010509
Pubmed

The role of neuropilins in cell signalling.

PLXNA3 PLXNA1

4.39e-05939219909241
Pubmed

Microglia ablation alleviates myelin-associated catatonic signs in mice.

NLGN4X NLGN4Y

4.39e-05939229252214
Pubmed

Plexin A3 and plexin A4 convey semaphorin signals during facial nerve development.

PLXNA3 PLXNA1

5.48e-051039218804103
InteractionRCOR1 interactions

SOX6 RLF MRTFB RAPH1 DNAJA1 MRTFA PRDM1

3.33e-05494387int:RCOR1
InteractionKDM1A interactions

GREB1L SOX6 RLF MRTFB RAPH1 DNAJA1 NSD2 MRTFA PRDM1

4.87e-05941389int:KDM1A
InteractionNCOA3 interactions

SOX6 MYOCD MRTFB NSD2 MRTFA

6.04e-05224385int:NCOA3
InteractionSEMA5A interactions

PLXNA3 PLXNA1

7.23e-057382int:SEMA5A
GeneFamilyPlexins

PLXNA3 PLXNA1

5.06e-059222683
GeneFamilyPHD finger proteins

SHPRH NSD2 ASH1L

1.72e-049022388
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

NSD2 ASH1L

7.74e-0434222487
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ADNP2 RLF ZIC4 PRDM1

1.02e-0271822428
GeneFamilyImmunoglobulin like domain containing

TEK ADAMTSL3

2.28e-02193222594
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 STON2 PRDM1

4.86e-07179395d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 STON2 PRDM1

5.42e-071833955a541a7f6c3514be8a13e988185dfe388c874f8b
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D GPNMB NLGN4X TEK

8.41e-072003954fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D GPNMB NLGN4X TEK

8.41e-07200395f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D GPNMB NLGN4X TEK

8.41e-07200395cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SOX6 PODN NLGN4X ADAMTSL3 GALNT8

8.41e-07200395a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D GPNMB NLGN4X TEK

8.41e-07200395310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D GPNMB NLGN4X TEK

8.41e-07200395c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D GPNMB NLGN4X TEK

8.41e-07200395961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D STON2 PRDM1

1.67e-05176394682a1dfcc507ec540f5fadf08e872533ea9f0291
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

1.71e-0517739491706bd0d4dda8d98843fb00b898d5aca4d66b64
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MUC19 CCDC88C NLGN4X TEK

1.75e-05178394c227da59dc7beb73f84405bf13356bdeb59d9338
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D STON2 PRDM1

1.91e-0518239408aff7112c9dac0ef5540300516a604782b21169
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L5-6_SST_KLHL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GREB1L SOX6 PODN PRDM1

1.95e-05183394439b1d1373b7cc73d65f3b59037a6def7cf8f4ba
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

1.99e-051843942ba98708dfd7f1b2a661578a334684094ff453ad
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

GREB1 MRTFB TEK ADAMTSL3

1.99e-0518439467164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

1.99e-051843947f6c8912677764d438ab0555faca344d74c2f483
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ZNF385D PODN MYOCD ADAMTSL3

2.03e-051853943b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellCOVID-19-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF385D TEK ADAMTSL3 STON2

2.03e-0518539436ce23893915f5c380cca39b2c33a516edf31c3a
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ZNF385D PODN GREB1 ADAMTSL3

2.03e-05185394fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCellCOVID-19-Neuronal_cells-Neuronal_cells|COVID-19 / group, cell type (main and fine annotations)

ZNF385D TEK ADAMTSL3 STON2

2.03e-051853944a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D STON2 PRDM1

2.03e-05185394f4ac62009c0ad3346e71b809e17727303c4df153
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L3-4_PVALB_HOMER3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

2.08e-05186394948815663c212c4311329d503b5991cbbbff9808
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

ZNF385D TEK ADAMTSL3 STON2

2.12e-051873941e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

ZNF385D PODN GREB1 ADAMTSL3

2.17e-05188394706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

2.17e-051883948de5a07301f9b5984680c873e5a92395b5ed3dd3
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

2.21e-0518939478cf414b98bcb19deb934409acddaad1cd51b67f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

2.26e-0519039426843ec1d19ac85a50990705353b802745d33e4d
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF385D PODN GREB1 ADAMTSL3

2.26e-051903947dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ZNF385D MYOCD GREB1 NLGN4Y

2.35e-0519239472881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

ZNF385D PODN GREB1 ADAMTSL3

2.35e-05192394d21f0f577156f17c899b08871046a26b88aea011
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D ADAMTSL3 PRDM1

2.40e-05193394d1445b8bf2bab36e1a326ddb2a528151db016c7d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

2.40e-051933944979862c0c16e6b4baa4c79894f1d237c861f5a5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D ADAMTSL3 PRDM1

2.40e-051933943ed46f5a7419ec4eddbd0df0d9b5f53aa486198b
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D ADAMTSL3 PRDM1

2.40e-05193394e74fdc8718fe0933e1f4dd3fe37e2134983b99b6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D ADAMTSL3 PRDM1

2.40e-05193394658c2b30a4d806c5ce78ea4392fe8eb86b8d1e99
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SOX6 PODN MYOCD ADAMTSL3

2.40e-05193394084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D GREB1 PRDM1

2.45e-05194394e5990880961d2469759ce4b3b20ae93ace3ebd1f
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D ADAMTSL3 PRDM1

2.45e-051943941bcb3fafd498614f7bac2b1c9b7de56e39110f65
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D ADAMTSL3 PRDM1

2.45e-0519439483863da11dfbe59b2d0a2c08db40b537c150588c
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPNMB PLXNA1 STON2 PRDM1

2.50e-05195394cad21edd90bf3e2fefdf5773a59cb1a664a69ddd
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GPNMB PLXNA1 STON2 PRDM1

2.50e-051953947e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellCOPD-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

ZNF385D PODN GREB1 GPNMB

2.55e-051963944930eeb303d174c28fd91021723e26fdf1af9170
ToppCelldistal-2-mesenchymal-Vascular_Smooth_Muscle|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SOX6 PODN MYOCD ADAMTSL3

2.65e-05198394ce05ede69c167b2294630709bb0c223483a6ef75
ToppCellILEUM-non-inflamed-(8)_Smooth_muscle_cells|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SOX6 PODN MYOCD ADAMTSL3

2.71e-051993943368c0a90a47c4dcdfe70be3192550df0744e508
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

AGO1 ADAMTSL3 RNF103 PLXNA1

2.71e-0519939433ffea12b8228e0b5bd8942531c3b21d24224725
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D STON2 PRDM1

2.76e-052003943cbb01039d1e7635ec4dcdf0223587f7ea3c7b34
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-GXYLT2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

GREB1L SOX6 PODN PRDM1

2.76e-05200394fe63aa1febd2bf650a7dd4e8b4420063580644ba
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385D PODN GREB1 ADAMTSL3

2.76e-05200394ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D ADAMTSL3 PRDM1

2.76e-052003948d51b4f7b7002ee51401ebe5eaca1e8f04bfadd5
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D STON2 PRDM1

2.76e-05200394107854f4855fc99c9f7e737eb246f0d868e6c5fd
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D ADAMTSL3 PRDM1

2.76e-052003946a44439e4a7ce3627271375b04cfcfb9467218f4
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-TH|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 GPNMB STON2 PRDM1

2.76e-052003943ece392f336547aea7dea625d9102819b04b4f7a
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D STON2 PRDM1

2.76e-0520039497a010a1b6d551239cf6ea5a43319fb413ff180e
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-GXYLT2|Neuronal / cells hierarchy compared to all cells using T-Statistic

GREB1L SOX6 PODN PRDM1

2.76e-0520039437728d83b246dd70933d1f52f938bc1c401df7b9
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-STK32A--L4-5|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D ADAMTSL3 PRDM1

2.76e-05200394cb1f4b0d66da5b0466ff17b29e7034d451d93e4f
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-TH--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 GPNMB STON2 PRDM1

2.76e-05200394e9b5105fff7845a98f962d609c2055528583b48e
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ZNF385D PODN GREB1 ADAMTSL3

2.76e-0520039474e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-GXYLT2--L4-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

GREB1L SOX6 PODN PRDM1

2.76e-05200394cafa1b46d0b052fca6191ad99d5862a07d0a1fd2
ToppCellNeuronal-Inhibitory-iB-iB_3(PVALB-SST)-MIR548F2|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 ZNF385D STON2 PRDM1

2.76e-052003948ccf2dbbe34b26fbf2bbef1e64b4ae636edd6672
ToppCellNeuronal-Inhibitory-iB-iB_4(SST)-TH-|Neuronal / cells hierarchy compared to all cells using T-Statistic

SOX6 GPNMB STON2 PRDM1

2.76e-05200394fa0d4a0c93b0b0ad0331e7b7013373be27958c4e
ToppCellLPS_only-Myeloid-Dendritic_cells-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GPNMB STON2 PRDM1

1.29e-041123939801227fe5a6f5ae1b6c5a9e7fa7f35c4c52efe1
ToppCell(05)_Ciliated-(2)_48hpi|(05)_Ciliated / shred by cell type and Timepoint

GREB1 GPNMB FMNL1

1.74e-04124393fc8cce8c1809edafbc4e69e501dd4f016f5dfc0b
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-9|TCGA-Brain / Sample_Type by Project: Shred V9

GREB1L OSGIN2 ADAMTSL3

2.18e-041343932647453f44b0e0a8f27ef9bba750e99eb40efc8b
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PLXNA3 MYOCD ADAMTSL3

2.81e-041463932ac9b487a7991fdc15444aeb93533030e09825bb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SOX6 NLGN4X ADAMTSL3

3.16e-04152393eee86b508b8f140ea44e21d8c04c409a7b689e39
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GREB1L MYOCD NLGN4Y

3.28e-0415439316fdafb5c64d2db321554f87129a962d113f1668
ToppCell-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

PODN GREB1 PRDM1

3.41e-04156393f0c4d9d58365b0ae8e10ba1aaf3847fb3f98c7ad
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L HKDC1 GPNMB

3.54e-04158393f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L HKDC1 GPNMB

3.54e-041583938c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HKDC1 GALNT8 PRDM1

3.60e-0415939308a1cd71eac4322fb313324f74fe8e37998f2d7d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg-Treg_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HKDC1 GALNT8 PRDM1

3.60e-041593939bdfa7f5aa7753fe25b787bd43d694b6093d77eb
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF385D OAS1 TEK

4.02e-041653936a621b300442c52adfc15b61d3a6d3a3cb00099f
ToppCellNS-critical-d_0-4-Myeloid-Monocyte-derived_DC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GREB1L GPNMB ADAMTSL3

4.31e-041693936fe82db874eff0f86e5c0d1cc81322eb9d7874eb
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

GPNMB RAPH1 NLGN4Y

4.31e-04169393e3100eb587005e160bd0b7990fa57ec49765133d
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCDC88C MYOCD PRDM1

4.31e-04169393f06118754fa62c580b4bcbecff6f9e5fdc2106a0
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D122|Adult / Lineage, Cell type, age group and donor

ZNF385D TEK NLGN4Y

4.38e-04170393a99cb3d21f8eb926886340ea99491e078e607648
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D MRTFB TEK

4.38e-041703931a568efcff9c39b3f709b55a05d24710450a2657
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ZNF385D MRTFB TEK

4.38e-0417039366d41d794790e621d72ac37af995510537103c9c
ToppCellmetastatic_Brain-B_lymphocytes-Undetermined|B_lymphocytes / Location, Cell class and cell subclass

OAS1 RAPH1 RNF103

4.46e-041713930d14bc9688c427ba2265984987dc3eea195b19eb
ToppCell390C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

OSGIN2 PLXNA1 GALNT8

4.46e-0417139370963f79711fe6088d6d01b29206b17ab89e5e73
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC19 NLGN4X TEK

4.53e-04172393de9b11ab109d04937186c09772cec9105a935f95
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

ZNF385D MRTFB TEK

4.53e-04172393a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCell390C-Lymphocytic-ILC-ILC-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

OSGIN2 PLXNA1 GALNT8

4.53e-0417239384d16cd7f618c94888920680bdc9e7130d73fd75
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel|Adult / Lineage, Cell type, age group and donor

ZNF385D TEK NLGN4Y

4.53e-04172393ad4ffdb3fc0c560a9cbaa2bc048476cbc43e8fd6
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MRTFB TEK PRDM1

4.69e-04174393cb0109661e8c9ca04d67d33f2d926f0e649bf67d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PODN NLGN4X NLGN4Y

4.69e-041743939c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PODN NLGN4X NLGN4Y

4.69e-04174393bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 MYOCD GPNMB

4.69e-04174393eb8012823b08729b462d1e5212f4873bb6b4eb1e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 MYOCD GPNMB

4.69e-0417439332fdeeebeeeca657eac6329caad4c28ca54e4d1c
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLXNA3 MYOCD ADAMTSL3

4.69e-04174393a7ade7372e83edd4e3983e77f8417b51f0b47340
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D PRDM1

4.77e-0417539329a4197ad4b2382257d7cc9ff237726bb60bc06d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L2-4_SST_AHR|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SOX6 ZNF385D PRDM1

4.85e-04176393322259a35f5c97d73ce7f75835dcdb5c954c91f8
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

ZNF385D NLGN4X STON2

4.85e-04176393c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

GPNMB FMNL1 STON2

4.85e-0417639398176bf3c961d5262593e2d5d002836adb010e13
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

ZNF385D NLGN4X STON2

4.85e-0417639398c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCellCOVID-19-Heart-Lymph_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ZNF385D ADAMTSL3 STON2

4.93e-04177393326fde0734ef0d7272693966d346ca479b9d8147
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MUC19 NLGN4X TEK

4.93e-041773935ff8dcfb030312126695d53a026d2e104a401b83
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

OAS1 DNAJA1 NLGN4Y

4.93e-04177393a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GPNMB RAPH1 PRDM1

5.01e-04178393a28683690ab8a60eb18f3ef87ea85da4e95b22df
Disease2-hydroxystearate measurement

MUC19 TEK

5.78e-059382EFO_0021059
Diseaseautism spectrum disorder (implicated_via_orthology)

NLGN4X NLGN4Y ASH1L

9.91e-04152383DOID:0060041 (implicated_via_orthology)
Diseaseretinitis pigmentosa (is_implicated_in)

HKDC1 PRPF8

1.28e-0341382DOID:10584 (is_implicated_in)
Diseasenon-high density lipoprotein cholesterol measurement

ADNP2 PLXNA3 ZIC4 RAI1 PRDM1

2.11e-03713385EFO_0005689
Diseaseuterine fibroid

MYOCD GREB1 MRTFA

2.14e-03199383EFO_0000731
Diseaseantisaccade response measurement

SOX6 GALNT8

2.38e-0356382EFO_0006874
DiseaseAlzheimer's disease (implicated_via_orthology)

SOX6 DNAJA1

2.46e-0357382DOID:10652 (implicated_via_orthology)
DiseaseIntellectual Disability

AGO1 NSD2 RAI1 ASH1L

2.55e-03447384C3714756
Diseasecreatine kinase measurement

GPNMB MRTFA

2.64e-0359382EFO_0004534
Diseasehypertension, white matter hyperintensity measurement

ZNF385D CCDC88C

2.91e-0362382EFO_0000537, EFO_0005665
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

GREB1 RAPH1

3.79e-0371382EFO_0004735, EFO_0007965

Protein segments in the cluster

PeptideGeneStartEntry
KPKYSPYNKLQKTAH

ZNF385D

301

Q9H6B1
KHNQLYKKPDVPLYK

ASH1L

2061

Q9NR48
LLNLPPKKKNADYYE

ASH1L

2471

Q9NR48
LLVYKKHKEYNPIEN

GPNMB

516

Q14956
KQKYNLQLKYPHLPC

AGO1

311

Q9UL18
AKPPKKSYVNYKVLQ

C1orf131

201

Q8NDD1
LQDHVKKSTAPYKYP

ACSM4

536

P0C7M7
YRKLALKYHPDKNPN

DNAJA1

26

P31689
QFLKDYFHKKPYPSK

ADNP2

1056

Q6IQ32
YYPEHCLPKKKPKLK

RAI1

1706

Q7Z5J4
KHPQIQKKSQYIKYL

RAPH1

471

Q70E73
YKLHLKNNKLEKIPP

PODN

241

Q7Z5L7
TQPKKQKHLKYYLVR

GREB1

181

Q4ZG55
VQPKYKHVYPKNSVV

NUDT19

356

A8MXV4
YQQKPDQAPKLLIKY

IGKV6D-41

56

A0A0C4DH26
QYKFYDPPPKKKNHW

CCDC88C

1391

Q9P219
PSNKLLYAKDIPNYK

PLXNA1

1796

Q9UIW2
PSNKLLYAKDIPNYK

PLXNA3

1771

P51805
QIPYNNKLIHIKKYG

MUC19

556

Q7Z5P9
YKHIKVNKPYGKVQI

NSD2

991

O96028
KPRVKKLKYHQYIPP

MRTFB

286

Q9ULH7
YQNCKKKLGKLPPQY

OAS1

216

P00973
TTQPKKQKHLKYYLV

GREB1L

206

Q9C091
PKPKVKKLKYHQYIP

MYOCD

256

Q8IZQ8
KKLKYHQYIPPDQKA

MYOCD

261

Q8IZQ8
KYNPKDQLYLHIGLK

NLGN4Y

561

Q8NFZ3
IFKQLPKKLYPEYHK

OSGIN2

341

Q9Y236
HLDEKIKLYNQKYPG

GALNT8

231

Q9NY28
VKNPPAAYIQKLKSY

FMNL1

76

O95466
SYKKKQPYAQHQPLS

RNF103

666

O00237
KYNPKDQLYLHIGLK

NLGN4X

561

Q8N0W4
LYKIHPQYPKRLHKV

HKDC1

416

Q2TB90
YDEKNLKIKPFYCPH

SHPRH

691

Q149N8
PNKKNSYPHYVKSIV

MT-ND5

26

P03915
TLPYPLKKQNGKIKY

PRDM1

561

O75626
PKVKKLKYHQYIPPD

MRTFA

231

Q969V6
YKEKKKYQPKPAVAH

STON2

506

Q8WXE9
HLEKYPNYKYKPRPK

SOX6

681

P35712
LKYYVLNALKHRPPK

PRPF8

451

Q6P2Q9
YHFKPKKIKTKDLFP

RLF

981

Q13129
IKSKKLLYKPVNHYE

TEK

476

Q02763
QGKPFKAKYKLVNHI

ZIC4

181

Q8N9L1
HYYPENVKPKPKLKE

ADAMTSL3

381

P82987